BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC139744.6 + phase: 1 /partial
(384 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_624161.1| PREDICTED: similar to CG4008-PA [Apis mellifera] 678 0.0
ref|XP_317113.2| ENSANGP00000019665 [Anopheles gambiae str. PEST... 649 0.0
gb|EAL33421.1| GA17851-PA [Drosophila pseudoobscura] 646 0.0
gb|AAF52807.1| CG4008-PA [Drosophila melanogaster] gi|17137568|r... 642 0.0
gb|AAC05144.1| methionine aminopeptidase [Drosophila melanogaster] 642 0.0
gb|AAH55563.1| Methionine aminopeptidase 2 [Danio rerio] gi|4105... 627 e-178
gb|AAH68393.1| Unknown (protein for IMAGE:6961702) [Danio rerio] 627 e-178
ref|NP_001006233.1| similar to initiation factor 2-associated 67... 614 e-174
ref|NP_001016115.1| hypothetical protein LOC548869 [Xenopus trop... 613 e-174
ref|NP_062622.1| methionine aminopeptidase 2 [Mus musculus] gi|6... 612 e-174
sp|P38062|AMPM2_RAT Methionine aminopeptidase 2 (MetAP 2) (Pepti... 612 e-174
gb|AAH91150.1| Initiation factor 2 associated 67 kDa protein [Ra... 612 e-174
gb|AAH70892.1| Metap2 protein [Rattus norvegicus] 612 e-174
ref|XP_509279.1| PREDICTED: methionyl aminopeptidase 2 [Pan trog... 610 e-173
pdb|1KQ9|A Chain A, Human Methionine Aminopeptidase Type Ii In C... 610 e-173
gb|AAH43889.1| Metap2-prov protein [Xenopus laevis] 609 e-173
gb|AAH73553.1| LOC443662 protein [Xenopus laevis] gi|67678468|gb... 604 e-171
ref|XP_574154.1| PREDICTED: similar to Methionine aminopeptidase... 601 e-170
emb|CAG04172.1| unnamed protein product [Tetraodon nigroviridis] 600 e-170
dbj|BAC03733.1| unnamed protein product [Homo sapiens] 595 e-169
>ref|XP_624161.1| PREDICTED: similar to CG4008-PA [Apis mellifera]
Length = 474
Score = 678 bits (1749), Expect = 0.0
Identities = 324/386 (83%), Positives = 355/386 (91%), Gaps = 4/386 (1%)
Query: 3 EAQKKKKNKKKKGK--KVQTDPPTIPICELFSDGVYPIGQIMDYPTVN--DSRTAKDRFT 58
+ +KKKK +K +GK K QTDPPTIP+ ELFSDG +PIGQIMD+P D RTAK+RF+
Sbjct: 88 DIKKKKKKRKSRGKGPKQQTDPPTIPVSELFSDGNFPIGQIMDHPPAAGIDDRTAKERFS 147
Query: 59 NEEKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKED 118
+EE RA DR +DIYNE R AAEAHRQTRKH+ +W+KPGMTMI+IC ELENTARKLI ED
Sbjct: 148 SEEARAFDRMHNDIYNEARQAAEAHRQTRKHIMKWVKPGMTMIEICNELENTARKLIGED 207
Query: 119 GLKAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNP 178
GLKAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTL+FNP
Sbjct: 208 GLKAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLAFNP 267
Query: 179 KYDKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGH 238
KYDKLIEAVRDATNTGIKAAGIDV LC++GAAIQEVMESYE+ELDGKTY VKSIRNLNGH
Sbjct: 268 KYDKLIEAVRDATNTGIKAAGIDVQLCDVGAAIQEVMESYEIELDGKTYPVKSIRNLNGH 327
Query: 239 SISPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGY 298
SI+PYRIHAGKTVPIVKGGEAT MEENE+YAIETFGSTGRG VHDD+DCSHYMK+FDAG+
Sbjct: 328 SIAPYRIHAGKTVPIVKGGEATRMEENEFYAIETFGSTGRGIVHDDLDCSHYMKSFDAGF 387
Query: 299 MPLRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVK 358
+PLRLQSSKSLL+VINK+F TLAFCKRWLDR GCTKYQMALKDLCDKG V+AYPPL DVK
Sbjct: 388 VPLRLQSSKSLLNVINKHFGTLAFCKRWLDRVGCTKYQMALKDLCDKGAVEAYPPLVDVK 447
Query: 359 GCYTAQFEHTIMLRPTCKEVVSRGDD 384
GCYTAQFEHT++LRPTCKEV+SRGDD
Sbjct: 448 GCYTAQFEHTLVLRPTCKEVISRGDD 473
>ref|XP_317113.2| ENSANGP00000019665 [Anopheles gambiae str. PEST]
gi|55237348|gb|EAA12286.2| ENSANGP00000019665 [Anopheles
gambiae str. PEST]
Length = 438
Score = 649 bits (1675), Expect = 0.0
Identities = 315/383 (82%), Positives = 345/383 (89%), Gaps = 3/383 (0%)
Query: 2 GEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEE 61
G+ ++KK+NKKK P++PI E FSDG +P GQIM YP DS TAKDRFT+EE
Sbjct: 58 GKKKRKKRNKKKGAAANTLVAPSVPIAEQFSDGKFPEGQIMQYP---DSTTAKDRFTSEE 114
Query: 62 KRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLK 121
KRALDR DIY+E+R AAEAHRQTR++MQ+WIKPGMTMI+ICEELENTAR+LI E+GL+
Sbjct: 115 KRALDRMHQDIYSELRQAAEAHRQTRQYMQKWIKPGMTMIEICEELENTARRLIGENGLE 174
Query: 122 AGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYD 181
AGLAFPTGCSRNHCAAHYTPNAGDPTVL YDDVTKIDFGTHI GRIIDCAFTLSFNPKYD
Sbjct: 175 AGLAFPTGCSRNHCAAHYTPNAGDPTVLLYDDVTKIDFGTHIKGRIIDCAFTLSFNPKYD 234
Query: 182 KLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSIS 241
KL+EAV++AT TGI+ AGIDV LC+IGAAIQEVMESYEVELDGKTYQVK+IRNLNGHSIS
Sbjct: 235 KLLEAVKEATETGIREAGIDVRLCDIGAAIQEVMESYEVELDGKTYQVKAIRNLNGHSIS 294
Query: 242 PYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMPL 301
PYRIHAGKTVPIVKGGE T MEENE+YAIETFGSTGRG VHDDMDCSHYMK+FDA +PL
Sbjct: 295 PYRIHAGKTVPIVKGGETTRMEENEFYAIETFGSTGRGLVHDDMDCSHYMKDFDAPKVPL 354
Query: 302 RLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGCY 361
RLQSSKSLL +IN+NF TLAFCKRWLDRAG TKYQMALKDLCDKGIV+AYPPLCDVKG Y
Sbjct: 355 RLQSSKSLLGLINRNFGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDVKGSY 414
Query: 362 TAQFEHTIMLRPTCKEVVSRGDD 384
TAQ+EHTIMLRPTCKEVVSRGDD
Sbjct: 415 TAQYEHTIMLRPTCKEVVSRGDD 437
>gb|EAL33421.1| GA17851-PA [Drosophila pseudoobscura]
Length = 461
Score = 646 bits (1666), Expect = 0.0
Identities = 310/384 (80%), Positives = 345/384 (89%), Gaps = 3/384 (0%)
Query: 4 AQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPT---VNDSRTAKDRFTNE 60
A KKK NK KK QT+PPTIPI +LF GV+P G+I+++PT + D RTAKDR T+E
Sbjct: 77 AAKKKNNKGKKAGNGQTEPPTIPIAKLFPSGVFPEGEIVEHPTPKDLPDDRTAKDRLTSE 136
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EKRALDR ++IY E+R AAEAHRQTR++MQ++IKPGMTMIQICEELENTAR+LI E+GL
Sbjct: 137 EKRALDRMNTEIYQELRQAAEAHRQTRQYMQRFIKPGMTMIQICEELENTARRLIGENGL 196
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS NHCAAHYTPNAGDPTVL+YDDV KIDFGTHI GRIIDCAFTL+FN KY
Sbjct: 197 DAGLAFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKY 256
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
DKL++AV++ATNTGIK AGIDV LC+IGAAIQEVMESYEVELDGKTY +K+IRNLNGHSI
Sbjct: 257 DKLLQAVKEATNTGIKEAGIDVRLCDIGAAIQEVMESYEVELDGKTYPIKAIRNLNGHSI 316
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
SPYRIHAGKTVPIVKGGE+T MEE+E+YAIETFGSTGRG VHDDMDCSHYMKNFD Y+P
Sbjct: 317 SPYRIHAGKTVPIVKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPYVP 376
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
LRLQSSK LL INKNF TLAFCKRWLDRAG TKYQMALKDLCDKGIV+AYPPLCD+KGC
Sbjct: 377 LRLQSSKQLLGTINKNFGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDIKGC 436
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQ+EHTIMLRPTCKE+VSRGDD
Sbjct: 437 YTAQYEHTIMLRPTCKEIVSRGDD 460
>gb|AAF52807.1| CG4008-PA [Drosophila melanogaster] gi|17137568|ref|NP_477373.1|
CG4008-PA [Drosophila melanogaster]
gi|15010418|gb|AAK77257.1| GH03119p [Drosophila
melanogaster]
Length = 448
Score = 642 bits (1657), Expect = 0.0
Identities = 308/384 (80%), Positives = 345/384 (89%), Gaps = 3/384 (0%)
Query: 4 AQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPT---VNDSRTAKDRFTNE 60
AQ KK K K QTDPPTIPI +L+ DG +P G+I+++PT + D RTAKDRFT+E
Sbjct: 64 AQPAKKKGNKGKKSGQTDPPTIPIAKLYPDGNFPEGEIVEHPTPKDMPDDRTAKDRFTSE 123
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EKRALDR +DIY E+R AAEAHRQTR++MQ++IKPGMTMIQICEELENTAR+LI E+GL
Sbjct: 124 EKRALDRINTDIYQELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGL 183
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
+AGLAFPTGCS NHCAAHYTPNAGDPTVL+YDDV KIDFGTHI GRIIDCAFTL+FN KY
Sbjct: 184 EAGLAFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKY 243
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
DKL++AV++ATNTGI+ AGIDV LC+IGAAIQEVMESYE+ELDGKTY +K+IRNLNGHSI
Sbjct: 244 DKLLQAVKEATNTGIREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSI 303
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
SPYRIHAGKTVPIVKGGE+T MEE+E+YAIETFGSTGRG VHDDMDCSHYMKNFD ++P
Sbjct: 304 SPYRIHAGKTVPIVKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVP 363
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
LRLQSSK LL INKNF TLAFCKRWLDRAG TKYQMALKDLCDKGIV+AYPPLCD+KGC
Sbjct: 364 LRLQSSKQLLGTINKNFGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDIKGC 423
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQ+EHTIMLRPTCKEVVSRGDD
Sbjct: 424 YTAQYEHTIMLRPTCKEVVSRGDD 447
>gb|AAC05144.1| methionine aminopeptidase [Drosophila melanogaster]
Length = 448
Score = 642 bits (1657), Expect = 0.0
Identities = 308/384 (80%), Positives = 345/384 (89%), Gaps = 3/384 (0%)
Query: 4 AQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPT---VNDSRTAKDRFTNE 60
AQ KK K K QTDPPTIPI +L+ DG +P G+I+++PT + D RTAKDRFT+E
Sbjct: 64 AQPAKKKGNKGKKSGQTDPPTIPIAKLYPDGNFPEGEIVEHPTPKDMPDDRTAKDRFTSE 123
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EKRALDR +DIY E+R AAEAHRQTR++MQ++IKPGMTMIQICEELENTAR+LI E+GL
Sbjct: 124 EKRALDRINTDIYQELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGL 183
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
+AGLAFPTGCS NHCAAHYTPNAGDPTVL+YDDV KIDFGTHI GRIIDCAFTL+FN KY
Sbjct: 184 EAGLAFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKY 243
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
DKL++AV++ATNTGI+ AGIDV LC+IGAAIQEVMESYE+ELDGKTY +K+IRNLNGHSI
Sbjct: 244 DKLLQAVKEATNTGIREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSI 303
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
SPYRIHAGKTVPIVKGGE+T MEE+E+YAIETFGSTGRG VHDDMDCSHYMKNFD ++P
Sbjct: 304 SPYRIHAGKTVPIVKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVP 363
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
LRLQSSK LL INKNF TLAFCKRWLDRAG TKYQMALKDLCDKGIV+AYPPLCD+KGC
Sbjct: 364 LRLQSSKQLLGTINKNFGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDIKGC 423
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQ+EHTIMLRPTCKEVVSRGDD
Sbjct: 424 YTAQYEHTIMLRPTCKEVVSRGDD 447
>gb|AAH55563.1| Methionine aminopeptidase 2 [Danio rerio]
gi|41054491|ref|NP_955934.1| methionine aminopeptidase 2
[Danio rerio]
Length = 476
Score = 627 bits (1616), Expect = e-178
Identities = 294/380 (77%), Positives = 334/380 (87%)
Query: 5 QKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEEKRA 64
+KKKK KKKKG KVQTDPP+IPICEL+ GVY GQ +YP V D RTA R +NEEK+
Sbjct: 96 KKKKKKKKKKGPKVQTDPPSIPICELYPSGVYAKGQECEYPPVQDGRTAASRTSNEEKKF 155
Query: 65 LDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLKAGL 124
LD++ D++N+ R AAEAHRQ RK++Q WIKPGMTMI+ICE+LE+ +RKLIKE+GL AGL
Sbjct: 156 LDQANEDMWNDFRQAAEAHRQVRKYVQSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGL 215
Query: 125 AFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYDKLI 184
AFPTGCS NHCAAHYTPNAGDPTVL+YDDV KIDFGTHINGRIIDCAFT++FNPKYDKL+
Sbjct: 216 AFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHINGRIIDCAFTVTFNPKYDKLL 275
Query: 185 EAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSISPYR 244
EAV+DATNTGIK AGIDV LC+IG +IQEVMESYEV+LDGKTYQVK IRNLNGHSI YR
Sbjct: 276 EAVKDATNTGIKCAGIDVRLCDIGESIQEVMESYEVDLDGKTYQVKPIRNLNGHSIGQYR 335
Query: 245 IHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMPLRLQ 304
IHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNF+ G++P+RL
Sbjct: 336 IHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGMVHDDMECSHYMKNFEVGHVPIRLP 395
Query: 305 SSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGCYTAQ 364
+K LL+V+N+NF TLAFC+RWLDR G TKY MALK+LCD GI+D YPPLCD KGCYTAQ
Sbjct: 396 RAKHLLNVVNENFGTLAFCRRWLDRLGETKYLMALKNLCDLGIIDPYPPLCDTKGCYTAQ 455
Query: 365 FEHTIMLRPTCKEVVSRGDD 384
FEHTI+LRPTCKEVVSRGDD
Sbjct: 456 FEHTILLRPTCKEVVSRGDD 475
>gb|AAH68393.1| Unknown (protein for IMAGE:6961702) [Danio rerio]
Length = 473
Score = 627 bits (1616), Expect = e-178
Identities = 294/380 (77%), Positives = 334/380 (87%)
Query: 5 QKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEEKRA 64
+KKKK KKKKG KVQTDPP+IPICEL+ GVY GQ +YP V D RTA R +NEEK+
Sbjct: 93 KKKKKKKKKKGPKVQTDPPSIPICELYPSGVYAKGQECEYPPVQDGRTAASRTSNEEKKF 152
Query: 65 LDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLKAGL 124
LD++ D++N+ R AAEAHRQ RK++Q WIKPGMTMI+ICE+LE+ +RKLIKE+GL AGL
Sbjct: 153 LDQANEDMWNDFRQAAEAHRQVRKYVQSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGL 212
Query: 125 AFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYDKLI 184
AFPTGCS NHCAAHYTPNAGDPTVL+YDDV KIDFGTHINGRIIDCAFT++FNPKYDKL+
Sbjct: 213 AFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHINGRIIDCAFTVTFNPKYDKLL 272
Query: 185 EAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSISPYR 244
EAV+DATNTGIK AGIDV LC+IG +IQEVMESYEV+LDGKTYQVK IRNLNGHSI YR
Sbjct: 273 EAVKDATNTGIKCAGIDVRLCDIGESIQEVMESYEVDLDGKTYQVKPIRNLNGHSIGQYR 332
Query: 245 IHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMPLRLQ 304
IHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNF+ G++P+RL
Sbjct: 333 IHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGMVHDDMECSHYMKNFEVGHVPIRLP 392
Query: 305 SSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGCYTAQ 364
+K LL+V+N+NF TLAFC+RWLDR G TKY MALK+LCD GI+D YPPLCD KGCYTAQ
Sbjct: 393 RAKHLLNVVNENFGTLAFCRRWLDRLGETKYLMALKNLCDLGIIDPYPPLCDTKGCYTAQ 452
Query: 365 FEHTIMLRPTCKEVVSRGDD 384
FEHTI+LRPTCKEVVSRGDD
Sbjct: 453 FEHTILLRPTCKEVVSRGDD 472
>ref|NP_001006233.1| similar to initiation factor 2-associated 67kDa protein [Gallus
gallus] gi|53135475|emb|CAG32428.1| hypothetical protein
[Gallus gallus]
Length = 479
Score = 614 bits (1584), Expect = e-174
Identities = 288/384 (75%), Positives = 332/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKKKG KVQTDPP+IPIC+LF +YP G+ YP D RTA R T+E
Sbjct: 95 GAAGKKKKKKKKKKGPKVQTDPPSIPICDLFPSNIYPKGEECQYPPTQDGRTAAWRITSE 154
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 155 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 214
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGDPTVL YDD+ KIDFGT+ +GRIIDCAFT++FNPKY
Sbjct: 215 NAGLAFPTGCSLNNCAAHYTPNAGDPTVLHYDDICKIDFGTYYSGRIIDCAFTVTFNPKY 274
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D+L+EAV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 275 DRLLEAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 334
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 335 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 394
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 395 IRLPRAKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 454
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 455 YTAQFEHTILLRPTCKEVVSRGDD 478
>ref|NP_001016115.1| hypothetical protein LOC548869 [Xenopus tropicalis]
Length = 483
Score = 613 bits (1580), Expect = e-174
Identities = 289/384 (75%), Positives = 333/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKKKG K QTDPP+IPI EL+ GV+P GQ +YP D R+A R T+E
Sbjct: 99 GAAGKKKKKKKKKKGSKSQTDPPSIPISELYPSGVFPKGQECEYPATQDGRSAAWRTTSE 158
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+A+D++ +I+ + R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 159 EKKAMDQASEEIWTDFRQAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 218
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGDPTVL+YDDV KIDFGTHINGRIIDCAFT++FNPKY
Sbjct: 219 YAGLAFPTGCSLNNCAAHYTPNAGDPTVLQYDDVCKIDFGTHINGRIIDCAFTVTFNPKY 278
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
DKL+EAV+DATNTGIK +GIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 279 DKLLEAVKDATNTGIKCSGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 338
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 339 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 398
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 399 IRLPRAKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDMKGS 458
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 459 YTAQFEHTILLRPTCKEVVSRGDD 482
>ref|NP_062622.1| methionine aminopeptidase 2 [Mus musculus]
gi|62027546|gb|AAH92052.1| Methionine aminopeptidase 2
[Mus musculus] gi|16903103|gb|AAL30407.1| methionine
aminopeptidase 2 [Mus musculus]
gi|12805475|gb|AAH02213.1| Methionine aminopeptidase 2
[Mus musculus] gi|3023282|sp|O08663|AMPM2_MOUSE
Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2)
(Initiation factor 2 associated 67 kDa glycoprotein)
(p67) (p67eIF2) gi|26345674|dbj|BAC36488.1| unnamed
protein product [Mus musculus]
gi|2055254|dbj|BAA19789.1| initiation factor
2-associated 67kDa protein [Mus musculus]
Length = 478
Score = 612 bits (1578), Expect = e-174
Identities = 287/384 (74%), Positives = 334/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G KVQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 94 GATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 153
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 154 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 213
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 214 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 273
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L+ AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 274 DILLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 333
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 334 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 393
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 394 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 453
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 454 YTAQFEHTILLRPTCKEVVSRGDD 477
>sp|P38062|AMPM2_RAT Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation
factor 2 associated 67 kDa glycoprotein) (p67) (p67eIF2)
Length = 478
Score = 612 bits (1577), Expect = e-174
Identities = 286/384 (74%), Positives = 335/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G +VQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 94 GAAGKKKKKKKKKRGPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 153
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 154 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 213
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 214 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 273
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 274 DILLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 333
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 334 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 393
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 394 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 453
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 454 YTAQFEHTILLRPTCKEVVSRGDD 477
>gb|AAH91150.1| Initiation factor 2 associated 67 kDa protein [Rattus norvegicus]
Length = 478
Score = 612 bits (1577), Expect = e-174
Identities = 286/384 (74%), Positives = 335/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G +VQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 94 GAAGKKKKKKKKKRGPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 153
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 154 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 213
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 214 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 273
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 274 DILLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 333
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 334 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 393
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 394 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 453
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 454 YTAQFEHTILLRPTCKEVVSRGDD 477
>gb|AAH70892.1| Metap2 protein [Rattus norvegicus]
Length = 442
Score = 612 bits (1577), Expect = e-174
Identities = 286/384 (74%), Positives = 335/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G +VQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 58 GAAGKKKKKKKKKRGPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 117
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 118 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 177
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 178 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 237
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 238 DILLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 297
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 298 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 357
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 358 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 417
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 418 YTAQFEHTILLRPTCKEVVSRGDD 441
>ref|XP_509279.1| PREDICTED: methionyl aminopeptidase 2 [Pan troglodytes]
gi|15489376|gb|AAH13782.1| Methionyl aminopeptidase 2
[Homo sapiens] gi|1703273|sp|P50579|AMPM2_HUMAN
Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2)
(Initiation factor 2 associated 67 kDa glycoprotein)
(p67) (p67eIF2) gi|687243|gb|AAC63402.1|
eIF-2-associated p67 homolog [Homo sapiens]
gi|903982|gb|AAA82930.1| methionine aminopeptidase
gi|6980777|pdb|1B6A| Human Methionine Aminopeptidase 2
Complexed With Tnp-470 gi|5803092|ref|NP_006829.1|
methionyl aminopeptidase 2 [Homo sapiens]
gi|1094399|prf||2106146A initiation factor 2-associated
protein
Length = 478
Score = 610 bits (1574), Expect = e-173
Identities = 286/384 (74%), Positives = 334/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G KVQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 94 GATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 153
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 154 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 213
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 214 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 273
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 274 DTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 333
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
YRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 334 GQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 393
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 394 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 453
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 454 YTAQFEHTILLRPTCKEVVSRGDD 477
>pdb|1KQ9|A Chain A, Human Methionine Aminopeptidase Type Ii In Complex With L-
Methionine gi|40889074|pdb|1KQ0|A Chain A, Human
Methionine Aminopeptidase Type Ii In Complex With D-
Methionine gi|39654787|pdb|1QZY|A Chain A, Human
Methionine Aminopeptidase In Complex With Bengamide
Inhibitor Laf153 And Cobalt gi|5821858|pdb|1BOA| Human
Methionine Aminopeptidase 2 Complexed With Angiogenesis
Inhibitor Fumagillin gi|5821855|pdb|1BN5| Human
Methionine Aminopeptidase 2
Length = 478
Score = 610 bits (1573), Expect = e-173
Identities = 285/384 (74%), Positives = 334/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKK+G KVQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+E
Sbjct: 94 GATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSE 153
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 154 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 213
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 214 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 273
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 274 DTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 333
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
YRIHAGKTVPI+KGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 334 GQYRIHAGKTVPIIKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVP 393
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 394 IRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 453
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 454 YTAQFEHTILLRPTCKEVVSRGDD 477
>gb|AAH43889.1| Metap2-prov protein [Xenopus laevis]
Length = 462
Score = 609 bits (1571), Expect = e-173
Identities = 287/384 (74%), Positives = 332/384 (85%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G +KKKK KKKKG K QTDPP+IPI EL+ GV+P GQ +YPT D R+A R T+E
Sbjct: 78 GAAGKKKKKKKKKKGAKSQTDPPSIPISELYPSGVFPKGQECEYPTTQDGRSAAWRTTSE 137
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ +D++ +I+ + R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 138 EKKVMDQANEEIWTDFRQAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGL 197
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGDPTVL+YDDV KIDFGTHING IIDCAFT++FNPKY
Sbjct: 198 YAGLAFPTGCSLNNCAAHYTPNAGDPTVLQYDDVCKIDFGTHINGHIIDCAFTVTFNPKY 257
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
DKL+EAV+DATNTGI+ +GIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 258 DKLLEAVKDATNTGIRCSGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 317
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P
Sbjct: 318 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDLGHVP 377
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 378 IRLPRAKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDMKGS 437
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 438 YTAQFEHTILLRPTCKEVVSRGDD 461
>gb|AAH73553.1| LOC443662 protein [Xenopus laevis] gi|67678468|gb|AAH97576.1|
Unknown (protein for IMAGE:4031008) [Xenopus laevis]
Length = 480
Score = 604 bits (1558), Expect = e-171
Identities = 285/383 (74%), Positives = 330/383 (85%)
Query: 2 GEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEE 61
G A KKKK KKKKG K QTDPP+I I EL+ G++P GQ +YP D R+A R T+EE
Sbjct: 97 GAAGKKKKKKKKKGSKSQTDPPSIAISELYPSGIFPKGQECEYPATQDGRSAAWRATSEE 156
Query: 62 KRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLK 121
K+A+D++ +I+ + R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL
Sbjct: 157 KKAMDQASEEIWTDFRQAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLY 216
Query: 122 AGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYD 181
AGLAFPTGCS N+CAAHYTPNAGDPTVL+YDDV KIDFGTHINGRIIDCAFT++FNPKYD
Sbjct: 217 AGLAFPTGCSLNNCAAHYTPNAGDPTVLQYDDVCKIDFGTHINGRIIDCAFTVTFNPKYD 276
Query: 182 KLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSIS 241
KL+EAV+DATNTGI+ +GIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 277 KLLEAVKDATNTGIRCSGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIG 336
Query: 242 PYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMPL 301
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P+
Sbjct: 337 PYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPI 396
Query: 302 RLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGCY 361
RL +K LL+VIN+ F TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG Y
Sbjct: 397 RLPRAKHLLNVINEKFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDMKGSY 456
Query: 362 TAQFEHTIMLRPTCKEVVSRGDD 384
TAQFEHTI+LRP CKEVVSRGDD
Sbjct: 457 TAQFEHTILLRPNCKEVVSRGDD 479
>ref|XP_574154.1| PREDICTED: similar to Methionine aminopeptidase 2 (MetAP 2)
(Peptidase M 2) (Initiation factor 2 associated 67 kDa
glycoprotein) (p67) (p67eIF2) [Rattus norvegicus]
Length = 908
Score = 601 bits (1550), Expect = e-170
Identities = 282/384 (73%), Positives = 332/384 (86%)
Query: 1 GGEAQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNE 60
G A KKK KKK+G +VQTDPP++PIC+L+ +GV+P GQ +YP D +TA R T+E
Sbjct: 524 GDGAAGKKKKKKKRGPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGQTAAWRTTSE 583
Query: 61 EKRALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGL 120
EK+ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RK IKE+GL
Sbjct: 584 EKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKPIKENGL 643
Query: 121 KAGLAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKY 180
AGLAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKY
Sbjct: 644 NAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKY 703
Query: 181 DKLIEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSI 240
D L++AV+DATNTGIK AGID+ LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI
Sbjct: 704 DILLKAVKDATNTGIKCAGIDIRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSI 763
Query: 241 SPYRIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMP 300
PYRIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD ++P
Sbjct: 764 GPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVEHVP 823
Query: 301 LRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGC 360
+RL +K LL+VIN+NF TLAFC+RWLDR G +KY MALK+LCD GIVD YPPLCD+KG
Sbjct: 824 IRLPRTKHLLNVINENFDTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGS 883
Query: 361 YTAQFEHTIMLRPTCKEVVSRGDD 384
YTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 884 YTAQFEHTILLRPTCKEVVSRGDD 907
>emb|CAG04172.1| unnamed protein product [Tetraodon nigroviridis]
Length = 486
Score = 600 bits (1548), Expect = e-170
Identities = 288/393 (73%), Positives = 329/393 (83%), Gaps = 13/393 (3%)
Query: 5 QKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEEKRA 64
+KKKK K KKG K QTDPP++PICEL++ G YP+GQ +YP + D R+A R TNEE+RA
Sbjct: 93 KKKKKKKNKKGAKSQTDPPSVPICELYTSGTYPVGQECEYPLLQDGRSAVWRMTNEERRA 152
Query: 65 LDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLKAGL 124
LDR+ +++N+ R AAEAHRQ R+H++ +IKPG+TMI ICE LE+ +RKLIKE+ L AGL
Sbjct: 153 LDRANEEMWNDFRQAAEAHRQVRQHVRSFIKPGLTMIDICERLEDCSRKLIKENKLNAGL 212
Query: 125 AFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYDKLI 184
AFPTGCS NHCAAHYTPNAGD TVL+YDDV KIDFGTHINGRIIDCAFT++FNPKYDKL+
Sbjct: 213 AFPTGCSLNHCAAHYTPNAGDTTVLQYDDVCKIDFGTHINGRIIDCAFTVTFNPKYDKLL 272
Query: 185 EAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSISPYR 244
EAVR+ATNTGIK AGIDV LC+IG AI EVMESYEVELDGKTYQVK IRNLNGHSI YR
Sbjct: 273 EAVREATNTGIKNAGIDVRLCDIGEAIHEVMESYEVELDGKTYQVKPIRNLNGHSIGQYR 332
Query: 245 IHAGKTVPIVKGGEATVME-------------ENEYYAIETFGSTGRGQVHDDMDCSHYM 291
IHAGKTVPIVKGGEAT ME E E YAIETFGSTG+G VHDDM+CSHYM
Sbjct: 333 IHAGKTVPIVKGGEATRMEATVCVRTSVCSSQEGEVYAIETFGSTGKGVVHDDMECSHYM 392
Query: 292 KNFDAGYMPLRLQSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAY 351
KNFD G++P+RL +K LL+VIN+ F TLAFC+RWLDR G +KY MALK+LCD GIVD Y
Sbjct: 393 KNFDVGHVPIRLPRAKHLLNVINEKFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPY 452
Query: 352 PPLCDVKGCYTAQFEHTIMLRPTCKEVVSRGDD 384
PPLCD KGCYTAQFEHTI+LRPTCKEVVSRGDD
Sbjct: 453 PPLCDSKGCYTAQFEHTILLRPTCKEVVSRGDD 485
>dbj|BAC03733.1| unnamed protein product [Homo sapiens]
Length = 455
Score = 595 bits (1534), Expect = e-169
Identities = 280/381 (73%), Positives = 328/381 (85%)
Query: 4 AQKKKKNKKKKGKKVQTDPPTIPICELFSDGVYPIGQIMDYPTVNDSRTAKDRFTNEEKR 63
A + K+ + KVQTDPP++PIC+L+ +GV+P GQ +YP D RTA R T+EEK+
Sbjct: 74 ALEDKERDEDDEAKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKK 133
Query: 64 ALDRSESDIYNEVRLAAEAHRQTRKHMQQWIKPGMTMIQICEELENTARKLIKEDGLKAG 123
ALD++ +I+N+ R AAEAHRQ RK++ WIKPGMTMI+ICE+LE+ +RKLIKE+GL AG
Sbjct: 134 ALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAG 193
Query: 124 LAFPTGCSRNHCAAHYTPNAGDPTVLEYDDVTKIDFGTHINGRIIDCAFTLSFNPKYDKL 183
LAFPTGCS N+CAAHYTPNAGD TVL+YDD+ KIDFGTHI+GRIIDCAFT++FNPKYD L
Sbjct: 194 LAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTL 253
Query: 184 IEAVRDATNTGIKAAGIDVPLCEIGAAIQEVMESYEVELDGKTYQVKSIRNLNGHSISPY 243
++AV+DATNTGIK AGIDV LC++G AIQEVMESYEVE+DGKTYQVK IRNLNGHSI Y
Sbjct: 254 LKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQY 313
Query: 244 RIHAGKTVPIVKGGEATVMEENEYYAIETFGSTGRGQVHDDMDCSHYMKNFDAGYMPLRL 303
RIHAGKTVPIVKGGEAT MEE E YAIETFGSTG+G VHDDM+CSHYMKNFD G++P+RL
Sbjct: 314 RIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRL 373
Query: 304 QSSKSLLSVINKNFSTLAFCKRWLDRAGCTKYQMALKDLCDKGIVDAYPPLCDVKGCYTA 363
+K LL+VIN+NF TLAFC+RWLDR G +KY MALKDLCD GIVD YPPLCD+KG YTA
Sbjct: 374 PRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKDLCDLGIVDPYPPLCDIKGSYTA 433
Query: 364 QFEHTIMLRPTCKEVVSRGDD 384
QFEHTI+LRPTCKEVVSRGDD
Sbjct: 434 QFEHTILLRPTCKEVVSRGDD 454
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.318 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 671,871,058
Number of Sequences: 2540612
Number of extensions: 27749184
Number of successful extensions: 80653
Number of sequences better than 10.0: 406
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 79920
Number of HSP's gapped (non-prelim): 544
length of query: 384
length of database: 863,360,394
effective HSP length: 130
effective length of query: 254
effective length of database: 533,080,834
effective search space: 135402531836
effective search space used: 135402531836
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 76 (33.9 bits)
Medicago: description of AC139744.6