BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC127429.13 - phase: 0 /pseudo
(1603 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
emb|CAB79987.1| putative protein [Arabidopsis thaliana] gi|30637... 1779 0.0
dbj|BAD93700.1| helicase and polymerase containing protein TEBIC... 1566 0.0
emb|CAG11187.1| unnamed protein product [Tetraodon nigroviridis] 499 e-139
gb|AAR08421.1| DNA polymerase theta [Homo sapiens] 490 e-136
ref|NP_955452.1| DNA polymerase theta isoform 2 [Homo sapiens] 490 e-136
ref|NP_006587.3| DNA polymerase theta isoform 1 [Homo sapiens] 490 e-136
gb|AAN39838.1| DNA polymerase Q [Mus musculus] 486 e-135
ref|NP_084253.1| DNA polymerase theta [Mus musculus] gi|29825886... 486 e-135
gb|AAK39635.1| DNA polymerase theta [Homo sapiens] 484 e-134
ref|XP_622734.1| PREDICTED: similar to DNA polymerase theta [Mus... 478 e-133
emb|CAE47762.1| novel protein similar to humna DNA-directed poly... 476 e-132
ref|XP_221423.3| PREDICTED: similar to DNA polymerase theta [Rat... 469 e-130
emb|CAI56770.1| hypothetical protein [Homo sapiens] 468 e-130
ref|XP_545125.1| PREDICTED: similar to DNA polymerase theta isof... 449 e-124
ref|XP_564726.1| ENSANGP00000027910 [Anopheles gambiae str. PEST... 446 e-123
ref|XP_308346.2| ENSANGP00000019077 [Anopheles gambiae str. PEST... 446 e-123
ref|XP_416549.1| PREDICTED: similar to DNA polymerase theta isof... 446 e-123
gb|EAL27595.1| GA19301-PA [Drosophila pseudoobscura] 431 e-119
gb|AAF54858.1| CG6019-PA [Drosophila melanogaster] gi|17933644|r... 422 e-116
gb|AAX33507.1| LP14642p [Drosophila melanogaster] 422 e-116
>emb|CAB79987.1| putative protein [Arabidopsis thaliana] gi|3063700|emb|CAA18591.1|
putative protein [Arabidopsis thaliana]
gi|15233883|ref|NP_194996.1| DNA-directed DNA polymerase
family protein [Arabidopsis thaliana]
gi|7486403|pir||T04456 hypothetical protein F4D11.100 -
Arabidopsis thaliana
Length = 1548
Score = 1779 bits (4607), Expect = 0.0
Identities = 977/1623 (60%), Positives = 1157/1623 (71%), Gaps = 171/1623 (10%)
Query: 1 MAILVLPYVSICTEK----------AEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAV 50
MA+LVLPYVSIC EK AEHLE LLEPLGKHVRSYYGNQGGG+LPKDTSVAV
Sbjct: 1 MALLVLPYVSICAEKVSVVSPSILHAEHLEVLLEPLGKHVRSYYGNQGGGTLPKDTSVAV 60
Query: 51 CTIEKANSLINRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKS 110
CTIEKANSLINRLLEEGRLSE+GIIVIDELHMVGD RGYLLELMLTKLRYAAGEG S+S
Sbjct: 61 CTIEKANSLINRLLEEGRLSELGIIVIDELHMVGDQHRGYLLELMLTKLRYAAGEGSSES 120
Query: 111 SDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQ-----------AALYQTEFRP 159
S GE SG SS K DPA GLQIVGMSATMPNV AVADWLQ AALYQTEFRP
Sbjct: 121 SSGESSGTSSGKADPAHGLQIVGMSATMPNVGAVADWLQVSKTNHNLCVYAALYQTEFRP 180
Query: 160 VPLEEYIKVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRK 219
VPLEEYIKVG++IYNK ME+ RTIPK AD+GGKDPDH+VELCNEVVQEG SVLIFCSSRK
Sbjct: 181 VPLEEYIKVGSTIYNKKMEVVRTIPKAADMGGKDPDHIVELCNEVVQEGNSVLIFCSSRK 240
Query: 220 GCESTARHVAKFLKSFTVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHH 279
GCESTARH++K +K+ V+++ N EF DI SAI++LR+ P+G+DPVLEET P+GVA+HH
Sbjct: 241 GCESTARHISKLIKNVPVNVDGENSEFMDIRSAIDALRRSPSGVDPVLEETLPSGVAYHH 300
Query: 280 AGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQM 339
AGLTVEEREIVETCYRKGL+RVLTATSTLAAGVNLPARRVIFRQP IG DFIDGTRY QM
Sbjct: 301 AGLTVEEREIVETCYRKGLVRVLTATSTLAAGVNLPARRVIFRQPMIGRDFIDGTRYKQM 360
Query: 340 AGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSEDLNGMTHAILEVVAGG 399
+GRAGRTGIDTKG+SVLICKP ELK++M LLNE+CPPL SCLSED NGMTHAILEVVAGG
Sbjct: 361 SGRAGRTGIDTKGDSVLICKPGELKRIMALLNETCPPLQSCLSEDKNGMTHAILEVVAGG 420
Query: 400 IVQTANDIH---RKFLEWNEDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVL 456
IVQTA DIH RKFLEWNE+TKLY+TTPLGR SFGSSLCPEESLIVL DL RAREG V+
Sbjct: 421 IVQTAKDIHRYVRKFLEWNEETKLYTTTPLGRGSFGSSLCPEESLIVLDDLLRAREGLVM 480
Query: 457 ASDLHLVYLVTPINVDVEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGS 516
ASDLHLVYLVTPINV VEP+WE YYERF++LSPL+QSVGNRVGV EPFLMRMAHG + +
Sbjct: 481 ASDLHLVYLVTPINVGVEPNWELYYERFMELSPLEQSVGNRVGVVEPFLMRMAHGATVRT 540
Query: 517 -----NKSRWSNNKRQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEA 571
+ + + ++HG +S + SD+Q LRVCKRF+VALILS LVQE V EVCEA
Sbjct: 541 LNRPQDVKKNLRGEYDSRHGSTSMKMLSDEQMLRVCKRFFVALILSKLVQEASVTEVCEA 600
Query: 572 FKVARGMVQGLQENAGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIP 631
FKVARGMVQ LQENAGRF+SMV+VFCERLGWHD EGLVAKFQNRVSFGVRAE+VELT+IP
Sbjct: 601 FKVARGMVQALQENAGRFSSMVSVFCERLGWHDLEGLVAKFQNRVSFGVRAEIVELTSIP 660
Query: 632 YVKGSRARALYKAGLRTPLAIAEASIPELVKALFESSSWGTEGSAQRSLQFGVAKKIKNG 691
Y+KGSRARALYKAGLRT AIAEASIPE+VKALFESS+W EG+ QR + G+AKKIKNG
Sbjct: 661 YIKGSRARALYKAGLRTSQAIAEASIPEIVKALFESSAWAAEGTGQRRIHLGLAKKIKNG 720
Query: 692 ARKIVLDKAEEARIAAFSAFKSLGYDVPQFAPPISTAVCNSIR----KEVGSSSGSDTAD 747
ARKIVL+KAEEAR AAFSAFKSLG DV + + P+ A +S+ E S GS D
Sbjct: 721 ARKIVLEKAEEARAAAFSAFKSLGLDVNELSKPLPLAPASSLNGQETTERDISRGSVGPD 780
Query: 748 TSHSFIDTNHIDNSNVPA---LEKEKDLIKSSDNGALVSVEGKSDSVMPHSLSTVPVVVP 804
I+ H++ N EK +++ + G VS E S +P+
Sbjct: 781 GLQQSIE-GHMECENFDMDNHREKPSEVLGDATLG--VSSEINLTSRLPN--------FR 829
Query: 805 SINELSMTSGPAKIPDVTTLSVHLQKQNDKSIMHNGCHAQGTGEQDHRGNLASGNMINSS 864
I T+GP+ + +++ + + +++ I Q DH S N +
Sbjct: 830 PIGTAVGTNGPSAVSILSSDTFPIPVYDNREIKPKDNVEQHLTRNDHIP--LSSNKDGTG 887
Query: 865 RKGPINAVSSPGGLDSFLDLWDTVAEFYFDIHYIKRLELHSAAPFEVHGIAICWENSPMY 924
KGP+ A + GG DSFL+LW + EF+FD+HY K +L+S +E+HGIAICW SP+Y
Sbjct: 888 EKGPVTAGNISGGFDSFLELWGSAGEFFFDLHYNKLQDLNSRISYEIHGIAICWNCSPVY 947
Query: 925 YINLPRDILLSGNRKDDGFSLTACSSKQKVSSSNSKQDLMNAMHRWSRISKIIEKKEVRK 984
Y+NL +D+ + A K +V +S++ D++ + RW++ISKI+
Sbjct: 948 YVNLNKDLPNLECVEKQKLIEDAVIGKSEVLASHNMLDVIKS--RWNKISKIMG------ 999
Query: 985 FTWNLKVQIQVLKKPSVSVQRFGSLDTIDKNMHLEVVDNSYILLPPIHVKDAIDMCIVAW 1044
VLK P++S+QR L+ + + + E+VD S++++PP+H IDM IV W
Sbjct: 1000 ---------NVLKSPAISIQRCTRLN-LPEGIRDELVDGSWLMMPPLHTSHTIDMSIVIW 1049
Query: 1045 ILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVAQTRALCS 1104
ILWPDEE S+PN+DKEVKKRLSPE A AAN+ GRWRNQ+R+ AHNGCCRRVAQTRALCS
Sbjct: 1050 ILWPDEERHSNPNIDKEVKKRLSPEAAEAANRSGRWRNQIRRVAHNGCCRRVAQTRALCS 1109
Query: 1105 VLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAY 1164
LWK+LVSE+L++AL IE+PLVNVLADMELWGIG+D+EGC++AR +L +L+ LEK+A+
Sbjct: 1110 ALWKILVSEELLQALTTIEMPLVNVLADMELWGIGIDIEGCLRARNILRDKLRSLEKKAF 1169
Query: 1165 KLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGKHCLDALRV---------- 1214
+LAGMTFSL PADIA VLF LKLPIP+ ++KGK HPST KHCLD LR
Sbjct: 1170 ELAGMTFSLHNPADIANVLFGQLKLPIPENQSKGKLHPSTDKHCLDLLRYSEWLIAFPYI 1229
Query: 1215 ------------------------------NARD--------------YFVPTQDNWLLL 1230
N RD +FVPTQ+NWLLL
Sbjct: 1230 AFCFFIIKDNRLFELLSASVEHEVEFKLDKNGRDVSSDADRYKINARDFFVPTQENWLLL 1289
Query: 1231 TADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMV 1290
TADYSQIELRLMAHFS+DS+LI L +P+GDVFTMIAA+W G E SV R+QTK+++
Sbjct: 1290 TADYSQIELRLMAHFSRDSSLISKLSQPEGDVFTMIAAKWTGKAEDSVSPHDRDQTKRLI 1349
Query: 1291 YGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG*G--DLVP 1348
YGILYGMG N LAEQ++CTSDEA E+I +FKS+FP V SWL+E ++FC+ KG G L P
Sbjct: 1350 YGILYGMGANRLAEQLECTSDEAKEKIRSFKSSFPAVTSWLNETISFCQEKGWGCYRLFP 1409
Query: 1349 FLHFVYAFL-LNLNYLWAVCNLIMCKYIHDPDM*RLSREGNDFCQK*NLAVVQKNQKLRG 1407
L + A L + LN+++ YI Q L+G
Sbjct: 1410 LLFVLNAVLCVPLNHIFI--------YI---------------------------QTLKG 1434
Query: 1408 KLSIPFVRCNTLFSFSSKSGYVSLQAVSIHVNIVFLPSTSQGSAADIIKIAMIKIYSEIF 1467
+ F + + QAV+ S QGSAADIIKIAMI IYS I
Sbjct: 1435 RRRF---LSKIKFGNAKEKSKAQRQAVN---------SMCQGSAADIIKIAMINIYSAIA 1482
Query: 1468 PGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLL 1527
VD SSSS +F ML+ RCRILLQVHDELVLEVDPS VK AA+LLQTSMENAVSLL
Sbjct: 1483 EDVDTAASSSSSETRFHMLKGRCRILLQVHDELVLEVDPSYVKLAAMLLQTSMENAVSLL 1542
Query: 1528 GLY 1530
G++
Sbjct: 1543 GMF 1545
>dbj|BAD93700.1| helicase and polymerase containing protein TEBICHI [Arabidopsis
thaliana]
Length = 2154
Score = 1566 bits (4056), Expect = 0.0
Identities = 821/1255 (65%), Positives = 963/1255 (76%), Gaps = 58/1255 (4%)
Query: 1 MAILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLI 60
MA+LVLPYVSIC EKAEHLE LLEPLGKHVRSYYGNQGGG+LPKDTSVAVCTIEKANSLI
Sbjct: 562 MALLVLPYVSICAEKAEHLEVLLEPLGKHVRSYYGNQGGGTLPKDTSVAVCTIEKANSLI 621
Query: 61 NRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSS 120
NRLLEEGRLSE+GIIVIDELHMVGD RGYLLELMLTKLRYAAGEG S+SS GE SG SS
Sbjct: 622 NRLLEEGRLSELGIIVIDELHMVGDQHRGYLLELMLTKLRYAAGEGSSESSSGESSGTSS 681
Query: 121 DKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELS 180
K DPA GLQIVGMSATMPNV AVADWLQAALYQTEFRPVPLEEYIKVG++IYNK ME+
Sbjct: 682 GKADPAHGLQIVGMSATMPNVGAVADWLQAALYQTEFRPVPLEEYIKVGSTIYNKKMEVV 741
Query: 181 RTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDIN 240
RTIPK AD+GGKDPDH+VELCNEVVQEG SVLIFCSSRKGCESTARH++K +K+ V+++
Sbjct: 742 RTIPKAADMGGKDPDHIVELCNEVVQEGNSVLIFCSSRKGCESTARHISKLIKNVPVNVD 801
Query: 241 ENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKGLLR 300
N EF DI SAI++LR+ P+G+DPVLEET P+GVA+HHAGLTVEEREIVETCYRKGL+R
Sbjct: 802 GENSEFMDIRSAIDALRRSPSGVDPVLEETLPSGVAYHHAGLTVEEREIVETCYRKGLVR 861
Query: 301 VLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLICKP 360
VLTATSTLAAGVNLPARRVIFRQP IG DFIDGTRY QM+GRAGRTGIDTKG+SVLICKP
Sbjct: 862 VLTATSTLAAGVNLPARRVIFRQPMIGRDFIDGTRYKQMSGRAGRTGIDTKGDSVLICKP 921
Query: 361 QELKKVMGLLNESCPPLHSCLSEDLNGMTHAILEVVAGGIVQTANDIHR----------- 409
ELK++M LLNE+CPPL SCLSED NGMTHAILEVVAGGIVQTA DIHR
Sbjct: 922 GELKRIMALLNETCPPLQSCLSEDKNGMTHAILEVVAGGIVQTAKDIHRYVRCTLLNSTK 981
Query: 410 -------------------KFLEWNEDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRA 450
KFLEWNE+TKLY+TTPLGR SFGSSLCPEESLIVL DL RA
Sbjct: 982 PFQDVVKSAQDSLRWLCHRKFLEWNEETKLYTTTPLGRGSFGSSLCPEESLIVLDDLLRA 1041
Query: 451 REGFVLASDLHLVYLVTPINVDVEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAH 510
REG V+ASDLHLVYLVTPINV VEP+WE YYERF++LSPL+QSVGNRVGV EPFLMRMAH
Sbjct: 1042 REGLVMASDLHLVYLVTPINVGVEPNWELYYERFMELSPLEQSVGNRVGVVEPFLMRMAH 1101
Query: 511 GVPMGSNKSRWSNNKR-----QNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPV 565
G + + K ++HG +S + SD+Q LRVCKRF+VALILS LVQE V
Sbjct: 1102 GATVRTLNRPQDVKKNLRGEYDSRHGSTSMKMLSDEQMLRVCKRFFVALILSKLVQEASV 1161
Query: 566 GEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVV 625
EVCEAFKVARGMVQ LQENAGRF+SMV+VFCERLGWHD EGLVAKFQNRVSFGVRAE+V
Sbjct: 1162 TEVCEAFKVARGMVQALQENAGRFSSMVSVFCERLGWHDLEGLVAKFQNRVSFGVRAEIV 1221
Query: 626 ELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKALFESSSWGTEGSAQRSLQFGVA 685
ELT+IPY+KGSRARALYKAGLRT AIAEASIPE+VKALFESS+W EG+ QR + G+A
Sbjct: 1222 ELTSIPYIKGSRARALYKAGLRTSQAIAEASIPEIVKALFESSAWAAEGTGQRRIHLGLA 1281
Query: 686 KKIKNGARKIVLDKAEEARIAAFSAFKSLGYDVPQFAPPISTAVCNSIR----KEVGSSS 741
KKIKNGARKIVL+KAEEAR AAFSAFKSLG DV + + P+ A +S+ E S
Sbjct: 1282 KKIKNGARKIVLEKAEEARAAAFSAFKSLGLDVNELSKPLPLAPASSLNGQETTERDISR 1341
Query: 742 GSDTADTSHSFIDTNHIDNSNVPA---LEKEKDLIKSSDNGALVSVEGKSDSVMPHSLST 798
GS D I+ H++ N EK +++ + G VS E S +P+
Sbjct: 1342 GSVGPDGLQQSIE-GHMECENFDMDNHREKPSEVLGDATLG--VSSEINLTSRLPN---- 1394
Query: 799 VPVVVPSINELSMTSGPAKIPDVTTLSVHLQKQNDKSIMHNGCHAQGTGEQDHRGNLASG 858
I T+GP+ + +++ + + +++ I Q DH S
Sbjct: 1395 ----FRPIGTAVGTNGPSAVSILSSDTFPIPVYDNREIKPKDNVEQHLTRNDHIP--LSS 1448
Query: 859 NMINSSRKGPINAVSSPGGLDSFLDLWDTVAEFYFDIHYIKRLELHSAAPFEVHGIAICW 918
N + KGP+ A + GG DSFL+LW + EF+FD+HY K +L+S +E+HGIAICW
Sbjct: 1449 NKDGTGEKGPVTAGNISGGFDSFLELWGSAGEFFFDLHYNKLQDLNSRISYEIHGIAICW 1508
Query: 919 ENSPMYYINLPRDILLSGNRKDDGFSLTACSSKQKVSSSNSKQDLMNAMHRWSRISKIIE 978
SP+YY+NL +D+ + A K +V +S++ D++ + RW++ISKI+
Sbjct: 1509 NCSPVYYVNLNKDLPNLECVEKQKLIEDAVIGKSEVLASHNMLDVIKS--RWNKISKIMG 1566
Query: 979 KKEVRKFTWNLKVQIQVLKKPSVSVQRFGSLDTIDKNMHLEVVDNSYILLPPIHVKDAID 1038
RKFTWNLKVQIQVLK P++S+QR L+ + + + E+VD S++++PP+H ID
Sbjct: 1567 NVNTRKFTWNLKVQIQVLKSPAISIQRCTRLN-LPEGIRDELVDGSWLMMPPLHTSHTID 1625
Query: 1039 MCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVAQ 1098
M IV WILWPDEE S+PN+DKEVKKRLSPE A AAN+ GRWRNQ+R+ AHNGCCRRVAQ
Sbjct: 1626 MSIVIWILWPDEERHSNPNIDKEVKKRLSPEAAEAANRSGRWRNQIRRVAHNGCCRRVAQ 1685
Query: 1099 TRALCSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQ 1158
TRALCS LWK+LVSE+L++AL IE+PLVNVLADMELWGIG+D+EGC++AR +L +L+
Sbjct: 1686 TRALCSALWKILVSEELLQALTTIEMPLVNVLADMELWGIGIDIEGCLRARNILRDKLRS 1745
Query: 1159 LEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGKHCLDALR 1213
LEK+A++LAGMTFSL PADIA VLF LKLPIP+ ++KGK HPST KHCLD LR
Sbjct: 1746 LEKKAFELAGMTFSLHNPADIANVLFGQLKLPIPENQSKGKLHPSTDKHCLDLLR 1800
Score = 198 bits (503), Expect = 1e-48
Identities = 90/133 (67%), Positives = 112/133 (83%)
Query: 1210 DALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAAR 1269
D ++NARD+FVPTQ+NWLLLTADYSQIELRLMAHFS+DS+LI L +P+GDVFTMIAA+
Sbjct: 1885 DRYKINARDFFVPTQENWLLLTADYSQIELRLMAHFSRDSSLISKLSQPEGDVFTMIAAK 1944
Query: 1270 WIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVAS 1329
W G E SV R+QTK+++YGILYGMG N LAEQ++CTSDEA E+I +FKS+FP V S
Sbjct: 1945 WTGKAEDSVSPHDRDQTKRLIYGILYGMGANRLAEQLECTSDEAKEKIRSFKSSFPAVTS 2004
Query: 1330 WLHEAVAFCRSKG 1342
WL+E ++FC+ KG
Sbjct: 2005 WLNETISFCQEKG 2017
Score = 129 bits (325), Expect = 6e-28
Identities = 81/149 (54%), Positives = 86/149 (57%), Gaps = 44/149 (29%)
Query: 1445 STSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEV 1504
S QGSAADIIKIAMI IYS I VD SSSS +F ML+ RCRILLQVHDELVLEV
Sbjct: 2050 SMCQGSAADIIKIAMINIYSAIAEDVDTAASSSSSETRFHMLKGRCRILLQVHDELVLEV 2109
Query: 1505 DPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIFT 1564
DPS VK AA+LLQTSMENAVSLL
Sbjct: 2110 DPSYVKLAAMLLQTSMENAVSLL------------------------------------- 2132
Query: 1565 VYAYASAVPLNVKLKVGRTWGSLEPFAPD 1593
VPL+VKLKVG+TWGSLEPF D
Sbjct: 2133 -------VPLHVKLKVGKTWGSLEPFQTD 2154
>emb|CAG11187.1| unnamed protein product [Tetraodon nigroviridis]
Length = 2382
Score = 499 bits (1284), Expect = e-139
Identities = 294/739 (39%), Positives = 412/739 (54%), Gaps = 110/739 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+L+LP+VS+ EK +L+ + E G V Y GN VAVCTIEKANSLIN
Sbjct: 79 ALLILPFVSVAKEKMHYLQSVFEEAGVRVEGYMGNVSAAGGFTSLDVAVCTIEKANSLIN 138
Query: 62 RLLEEGRLSEMG-----------------------IIVIDELHMVGDPKRGYLLELMLTK 98
RL+EE + +G ++V+DELHMVGD RGYLLEL+LTK
Sbjct: 139 RLIEEENMGLLGKNTWFFLTSWCHCDFKSPIFAPGMVVVDELHMVGDSGRGYLLELLLTK 198
Query: 99 LRYAAGEGISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFR 158
+ Y A + + + GS ++G+QI+GMSAT+PN++ +A WL A LYQT++R
Sbjct: 199 ICYIAQK--------QNTAGSL-----SEGIQIIGMSATLPNLSLLASWLCAELYQTDYR 245
Query: 159 PVPLEEYIKVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSR 218
PVPL+E++KVG +Y+K + + R ++ G D DH+V LC E V+EG SVL+FC S+
Sbjct: 246 PVPLQEHLKVGCKVYDKDLSVVRQFTPALNVQGDD-DHIVSLCYETVREGCSVLLFCPSK 304
Query: 219 KGCESTARHVAKFLKSFTVDINENNCEFADIT-------SAINSLRKCPAGLDPVLEETF 271
CE A +A+ + + N E ++ + L + PAGLD +L+ T
Sbjct: 305 NWCEKLADSIAREFYNLRNSEHSNEAELPPVSLDQQGLVDVVAQLGRTPAGLDSILQRTV 364
Query: 272 PAGVAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFI 331
P GVAFHHAGLT +ER+++E +R+GL+RVL ATSTL++GVNLPARRVI R P +
Sbjct: 365 PWGVAFHHAGLTFDERDVLEGAFRQGLVRVLAATSTLSSGVNLPARRVIVRTPTFNGHLL 424
Query: 332 DGTRYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSED-----LN 386
D Y QM+GRAGR G+DT GES+L+CK E K + LL S P+ SCL
Sbjct: 425 DPLTYKQMSGRAGRKGVDTIGESLLVCKEAERHKGISLLKGSLQPISSCLVRREGEGVTT 484
Query: 387 GMTHAILEVVAGGIVQTANDIH-----------------------------RKFLEW--- 414
M AILE++ GG+ T D+ +EW
Sbjct: 485 SMLRAILEIIVGGVASTPQDVRLYASCSLLAASLKLNMKKELDEETSKGAIEACVEWLMD 544
Query: 415 NE--------DTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLV 466
NE + +LY T LG A+ SSL P ESL V ADL RA +GFVL +DLH++YL+
Sbjct: 545 NEFISIQKEGEEELYCPTQLGAATLSSSLSPPESLAVFADLQRAMKGFVLENDLHILYLI 604
Query: 467 TPINVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNK 525
TP+ + DW ++ + +LS + V VGV E FL R G + + + +
Sbjct: 605 TPLYAEWTTIDWYQFFCLWEQLSSSMKRVAELVGVQEGFLARSVSGKIIAKTEKQ----R 660
Query: 526 RQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQEN 585
RQ + V KRF+ L+L LV E P+G V F RG +Q LQ++
Sbjct: 661 RQ----------------MAVHKRFFTTLVLHDLVNEVPLGTVASKFSCNRGQLQSLQQS 704
Query: 586 AGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAG 645
A +A MV VFC+RLGWH+ E L++++Q R+SFG++ E+V+L + +K +AR LY G
Sbjct: 705 ASTYAGMVTVFCKRLGWHNMELLLSQYQTRLSFGIQRELVDLVRVSLLKALQARTLYAQG 764
Query: 646 LRTPLAIAEASIPELVKAL 664
LRT +A A++ ++ KAL
Sbjct: 765 LRTVAELARATVADVEKAL 783
Score = 101 bits (251), Expect = 2e-19
Identities = 65/164 (39%), Positives = 87/164 (52%), Gaps = 13/164 (7%)
Query: 1190 PIPDGKN----KGKNHPST-------GKHCLDALRVNARDYFVPTQDNWLLLTADYSQIE 1238
P DG++ KGK S G A V+ R FVP ++L ADYSQ+E
Sbjct: 2070 PSQDGRHLAARKGKKRRSAVPSGAAAGSEQGPAFSVSMRHAFVPFSGG-MILAADYSQLE 2128
Query: 1239 LRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMG 1298
LR++AH SKD L+++L DVF IAA W SV R+Q K++ YGI+YGMG
Sbjct: 2129 LRVLAHLSKDQRLLQVLNG-GADVFRCIAAEWKSVDPDSVTDGLRQQAKQICYGIIYGMG 2187
Query: 1299 PNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I FKS + G+ ++L E V C G
Sbjct: 2188 AKSLGEQMGVEENDAACYIETFKSRYRGINAFLKETVKNCGKNG 2231
Score = 64.3 bits (155), Expect = 3e-08
Identities = 50/172 (29%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVA 1097
D + W+L P E + PN+ PE+ G ++H C R A
Sbjct: 1779 DPKVACWLLDPGSEERTLPNMVTVY----CPEELPLLGGLG--------SSHTHCPRVRA 1826
Query: 1098 QTRALCSV-----LWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLL 1152
T ++ + L LL + +++ +E+P LA +EL G+G C + + ++
Sbjct: 1827 STASVLTYAVMGRLTGLLREDGVLDHFRSVEMPSQVCLALLELNGVGFSAAECERQKHVM 1886
Query: 1153 VKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+L LE +AY+LAG +FSL+ D+A+VLF L LP P+G G T
Sbjct: 1887 QAKLAALEGQAYRLAGHSFSLTSVDDVAQVLFLELHLP-PNGDVNGSKSKKT 1937
>gb|AAR08421.1| DNA polymerase theta [Homo sapiens]
Length = 2592
Score = 490 bits (1262), Expect = e-136
Identities = 288/721 (39%), Positives = 410/721 (55%), Gaps = 91/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 140 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 199
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 200 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 258
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 259 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 311
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 312 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 370
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 371 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 430
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 431 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 490
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
GES+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 491 VGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 550
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 551 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 610
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 611 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 670
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 671 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 712
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 713 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 770
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 771 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 830
Query: 660 L 660
+
Sbjct: 831 V 831
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2280 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2339
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2340 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2398
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2399 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2440
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 1990 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2046
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2047 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2106
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2107 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2159
Score = 42.0 bits (97), Expect = 0.17
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2476 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDQTGLSRKRKLQGMFCPIRGGF 2535
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2536 FILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKL------------------------- 2570
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2571 -------------------SVKLKVKVKIGASWGELKDF 2590
>ref|NP_955452.1| DNA polymerase theta isoform 2 [Homo sapiens]
Length = 2592
Score = 490 bits (1262), Expect = e-136
Identities = 288/721 (39%), Positives = 410/721 (55%), Gaps = 91/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 140 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 199
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 200 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 258
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 259 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 311
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 312 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 370
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 371 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 430
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 431 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 490
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
GES+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 491 VGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 550
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 551 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 610
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 611 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 670
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 671 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 712
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 713 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 770
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 771 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 830
Query: 660 L 660
+
Sbjct: 831 V 831
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2280 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2339
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2340 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2398
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2399 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2440
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 1990 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2046
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2047 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2106
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2107 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2159
Score = 42.0 bits (97), Expect = 0.17
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2476 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDQTGLSRKRKLQGMFCPIRGGF 2535
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2536 FILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKL------------------------- 2570
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2571 -------------------SVKLKVKVKIGASWGELKDF 2590
>ref|NP_006587.3| DNA polymerase theta isoform 1 [Homo sapiens]
Length = 2725
Score = 490 bits (1262), Expect = e-136
Identities = 288/721 (39%), Positives = 410/721 (55%), Gaps = 91/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 273 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 332
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 333 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 391
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 392 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 444
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 445 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 503
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 504 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 563
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 564 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 623
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
GES+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 624 VGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 683
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 684 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 743
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 744 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 803
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 804 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 845
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 846 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 903
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 904 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 963
Query: 660 L 660
+
Sbjct: 964 V 964
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2413 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2472
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2473 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2531
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2532 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2573
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 2123 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2179
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2180 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2239
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2240 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2292
Score = 42.0 bits (97), Expect = 0.17
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2609 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDQTGLSRKRKLQGMFCPIRGGF 2668
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2669 FILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKL------------------------- 2703
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2704 -------------------SVKLKVKVKIGASWGELKDF 2723
>gb|AAN39838.1| DNA polymerase Q [Mus musculus]
Length = 2587
Score = 486 bits (1250), Expect = e-135
Identities = 287/724 (39%), Positives = 407/724 (55%), Gaps = 87/724 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN L+N
Sbjct: 182 ALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVN 241
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y KS+ + S+
Sbjct: 242 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVT----RKSASHQAESASTL 297
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
N +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E IK+GNSIY+ SM+L R
Sbjct: 298 SN----AVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVR 353
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DH+V LC E +Q+ SVLIFC S+K CE A +A+ +
Sbjct: 354 EFQPLLQVKG-DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEG 412
Query: 236 TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVET 292
V +E D + ++ L++ P+GLD VL+ T P GVAFHHAGLT EER+I+E
Sbjct: 413 LVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEG 472
Query: 293 CYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKG 352
+R+G +RVL ATSTL++GVNLPARRVI R P +D Y QM GRAGR G+DT G
Sbjct: 473 AFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMG 532
Query: 353 ESVLICKPQELKKVMGLLNESCPPLHSCL---SEDLNGMTHAILEVVAGGIVQTANDIH- 408
ES+L+CK E K + LL S P+HSCL E M AILE++ GG+ T+ D+
Sbjct: 533 ESILVCKNSEKSKGIALLQGSLEPVHSCLQRQGEVTASMIRAILEIIVGGVASTSQDMQT 592
Query: 409 --------------RKFLEWNEDT------------------------------KLYSTT 424
++ ++ N+D K+Y T
Sbjct: 593 YAACTFLAAAIQEGKQGMQRNQDDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPT 652
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYER 483
LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D + DW ++
Sbjct: 653 HLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWISIDWYRFFCL 712
Query: 484 FVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQT 543
+ KL + V VGV E FL R G + + + QH +
Sbjct: 713 WEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------RQ 752
Query: 544 LRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWH 603
+ + KRF+ +L+L L+ E P+ ++ + + RG +Q LQ++A +A M+ VF RLGWH
Sbjct: 753 MAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWH 812
Query: 604 DFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKA 663
+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+ A
Sbjct: 813 NMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVA 872
Query: 664 LFES 667
L S
Sbjct: 873 LKNS 876
Score = 101 bits (251), Expect = 2e-19
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W
Sbjct: 2309 VSMRHAFVPFPGG-LILAADYSQLELRILAHLSRDCRLIQVLNT-GADVFRSIAAEWKMI 2366
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+ K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ +
Sbjct: 2367 EPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRD 2426
Query: 1334 AVAFCRSKG 1342
V CR G
Sbjct: 2427 TVKNCRKNG 2435
Score = 61.6 bits (148), Expect = 2e-07
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2061 LLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAG 2120
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 2121 HSFSFTSADDIAQVLFLELKLP-PNGEMKTQGSKKT 2155
>ref|NP_084253.1| DNA polymerase theta [Mus musculus] gi|29825886|gb|AAL77225.1| DNA
polymerase theta [Mus musculus]
Length = 2544
Score = 486 bits (1250), Expect = e-135
Identities = 287/724 (39%), Positives = 407/724 (55%), Gaps = 87/724 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN L+N
Sbjct: 139 ALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVN 198
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y KS+ + S+
Sbjct: 199 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVT----RKSASHQAESASTL 254
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
N +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E IK+GNSIY+ SM+L R
Sbjct: 255 SN----AVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVR 310
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DH+V LC E +Q+ SVLIFC S+K CE A +A+ +
Sbjct: 311 EFQPLLQVKG-DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEG 369
Query: 236 TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVET 292
V +E D + ++ L++ P+GLD VL+ T P GVAFHHAGLT EER+I+E
Sbjct: 370 LVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEG 429
Query: 293 CYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKG 352
+R+G +RVL ATSTL++GVNLPARRVI R P +D Y QM GRAGR G+DT G
Sbjct: 430 AFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMG 489
Query: 353 ESVLICKPQELKKVMGLLNESCPPLHSCL---SEDLNGMTHAILEVVAGGIVQTANDIH- 408
ES+L+CK E K + LL S P+HSCL E M AILE++ GG+ T+ D+
Sbjct: 490 ESILVCKNSEKSKGIALLQGSLEPVHSCLQRQGEVTASMIRAILEIIVGGVASTSQDMQT 549
Query: 409 --------------RKFLEWNEDT------------------------------KLYSTT 424
++ ++ N+D K+Y T
Sbjct: 550 YAACTFLAAAIQEGKQGMQRNQDDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPT 609
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYER 483
LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D + DW ++
Sbjct: 610 HLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWISIDWYRFFCL 669
Query: 484 FVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQT 543
+ KL + V VGV E FL R G + + + QH +
Sbjct: 670 WEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------RQ 709
Query: 544 LRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWH 603
+ + KRF+ +L+L L+ E P+ ++ + + RG +Q LQ++A +A M+ VF RLGWH
Sbjct: 710 MAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWH 769
Query: 604 DFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKA 663
+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+ A
Sbjct: 770 NMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVA 829
Query: 664 LFES 667
L S
Sbjct: 830 LKNS 833
Score = 101 bits (251), Expect = 2e-19
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W
Sbjct: 2266 VSMRHAFVPFPGG-LILAADYSQLELRILAHLSRDCRLIQVLNT-GADVFRSIAAEWKMI 2323
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+ K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ +
Sbjct: 2324 EPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRD 2383
Query: 1334 AVAFCRSKG 1342
V CR G
Sbjct: 2384 TVKNCRKNG 2392
Score = 61.6 bits (148), Expect = 2e-07
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2018 LLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAG 2077
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 2078 HSFSFTSADDIAQVLFLELKLP-PNGEMKTQGSKKT 2112
>gb|AAK39635.1| DNA polymerase theta [Homo sapiens]
Length = 2724
Score = 484 bits (1245), Expect = e-134
Identities = 287/721 (39%), Positives = 409/721 (55%), Gaps = 92/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 273 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 332
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 333 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 391
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 392 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 444
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 445 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 503
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 504 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 563
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 564 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 623
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
G S+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 624 VG-SILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 682
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 683 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 742
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 743 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 802
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 803 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 844
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 845 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 902
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 903 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 962
Query: 660 L 660
+
Sbjct: 963 V 963
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2412 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2471
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2472 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2530
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2531 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2572
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 2122 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2178
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2179 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2238
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2239 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2291
Score = 41.2 bits (95), Expect = 0.29
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2608 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDRTGLSRKRKLQGMFCPIRGGF 2667
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2668 FILQLHDELLYEVVEEDVVQVAQIVKNEMESAVKL------------------------- 2702
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2703 -------------------SVKLKVKVKIGASWGELKDF 2722
>ref|XP_622734.1| PREDICTED: similar to DNA polymerase theta [Mus musculus]
Length = 2450
Score = 478 bits (1231), Expect = e-133
Identities = 286/724 (39%), Positives = 406/724 (55%), Gaps = 91/724 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+++ G V Y G+ +AVCTIE+AN L+N
Sbjct: 183 ALFILPFVSVAKEKKCYLQEV----GLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVN 238
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y KS+ + S+
Sbjct: 239 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVT----RKSASHQAESASTL 294
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
N +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E IK+GNSIY+ SM+L R
Sbjct: 295 SN----AVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVR 350
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DH+V LC E +Q+ SVLIFC S+K CE A +A+ +
Sbjct: 351 EFQPLLQVKG-DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEG 409
Query: 236 TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVET 292
V +E D + ++ L++ P+GLD VL+ T P GVAFHHAGLT EER+I+E
Sbjct: 410 LVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEG 469
Query: 293 CYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKG 352
+R+G +RVL ATSTL++GVNLPARRVI R P +D Y QM GRAGR G+DT G
Sbjct: 470 AFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMG 529
Query: 353 ESVLICKPQELKKVMGLLNESCPPLHSCL---SEDLNGMTHAILEVVAGGIVQTANDIH- 408
ES+L+CK E K + LL S P+HSCL E M AILE++ GG+ T+ D+
Sbjct: 530 ESILVCKNSEKSKGIALLQGSLEPVHSCLQRQGEVTASMIRAILEIIVGGVASTSQDMQT 589
Query: 409 --------------RKFLEWNEDT------------------------------KLYSTT 424
++ ++ N+D K+Y T
Sbjct: 590 YAACTFLAAAIQEGKQGMQRNQDDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPT 649
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYER 483
LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D + DW ++
Sbjct: 650 HLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWISIDWYRFFCL 709
Query: 484 FVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQT 543
+ KL + V VGV E FL R G + + + QH +
Sbjct: 710 WEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------RQ 749
Query: 544 LRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWH 603
+ + KRF+ +L+L L+ E P+ ++ + + RG +Q LQ++A +A M+ VF RLGWH
Sbjct: 750 MAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWH 809
Query: 604 DFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKA 663
+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+ A
Sbjct: 810 NMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVA 869
Query: 664 LFES 667
L S
Sbjct: 870 LKNS 873
Score = 101 bits (251), Expect = 2e-19
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W
Sbjct: 2172 VSMRHAFVPFPGG-LILAADYSQLELRILAHLSRDCRLIQVLNT-GADVFRSIAAEWKMI 2229
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+ K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ +
Sbjct: 2230 EPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRD 2289
Query: 1334 AVAFCRSKG 1342
V CR G
Sbjct: 2290 TVKNCRKNG 2298
Score = 61.6 bits (148), Expect = 2e-07
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 1924 LLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAG 1983
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 1984 HSFSFTSADDIAQVLFLELKLP-PNGEMKTQGSKKT 2018
>emb|CAE47762.1| novel protein similar to humna DNA-directed polymerase theta (POLQ)
[Danio rerio]
Length = 2254
Score = 476 bits (1224), Expect = e-132
Identities = 322/935 (34%), Positives = 467/935 (49%), Gaps = 153/935 (16%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ + + G V Y G+ VAVCTIEKAN L+N
Sbjct: 86 AMFILPFVSVAREKMFYLQNVFQEAGIRVEGYMGSTSAAGGFSALDVAVCTIEKANGLVN 145
Query: 62 RLLEEGRLSEMG---------------IIVIDELHMVGDPKRGYLLELMLTKLRYAAGEG 106
RL+EE +L +G +V+DELHMVGD RGYLLEL+LTK+RY A +
Sbjct: 146 RLIEEDKLDLLGKNNKKYLASYNVVTGTVVVDELHMVGDSGRGYLLELLLTKIRYIAQKT 205
Query: 107 ISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYI 166
+++S S G+QI+GMSAT+PN+ +A WL A LY T +RPVPL E++
Sbjct: 206 ATRNSGQSTS----------TGVQIIGMSATLPNLDLLARWLSAELYSTNYRPVPLMEWV 255
Query: 167 KVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTAR 226
K+G +IY+ S+ L D DH+V LC E VQ+G S L+FC S+ CE A
Sbjct: 256 KIGTNIYDGSLNLG------------DDDHIVSLCFETVQDGHSALLFCPSKNWCEKLAD 303
Query: 227 HVAKFLKSF------------TVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAG 274
+ + + ++ +N+ + + L++ PAGLD VL+ T P G
Sbjct: 304 SIGREFYNLHHKEMQSGSGGQSIFLNQEG-----LLDVLAQLKRTPAGLDHVLQRTVPWG 358
Query: 275 VAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGT 334
VAFHHAGLT +ER+I+E +R+G +RVL ATSTL++GVNLPARRVI R P +D
Sbjct: 359 VAFHHAGLTFDERDILEGAFRQGYIRVLAATSTLSSGVNLPARRVIIRTPVFNGHLLDIL 418
Query: 335 RYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSED-----LNGMT 389
Y QM GRAGR G+DT GESVL+CK E K M L+ S P+ SCL + M
Sbjct: 419 TYKQMVGRAGRKGVDTIGESVLVCKEAERAKGMSLIQGSLKPISSCLVKREGEGVTTSML 478
Query: 390 HAILEVVAGGIVQTANDIH--------------------------------RKFLEW--- 414
AILE++ GG+ + D+ +EW
Sbjct: 479 RAILEIIVGGVASSPQDVRMYAACTLLAASIAAEEAHQDGSESEARNKGAIEACIEWLMD 538
Query: 415 NE--------DTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLV 466
NE D + Y T LG A+ SSL P E+L + ADL RA +GFVL +DLH++Y +
Sbjct: 539 NEFIHIQKEGDVERYCPTHLGSATLSSSLSPPEALGIFADLQRAMKGFVLENDLHILYQI 598
Query: 467 TPINVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNK 525
TP+ VD DW ++ + +L + V VG+ E FL R G + + + +
Sbjct: 599 TPVYVDWTTIDWYQFFCLWEQLPSAMKRVAEMVGIQEGFLARSVGGKLIAKTEKQ----R 654
Query: 526 RQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQEN 585
RQ + + KRF+ L+L LV E P+G V + + +RG +Q LQ++
Sbjct: 655 RQ----------------MAIHKRFFTTLVLLDLVSEEPLGAVAKKYGCSRGQLQSLQQS 698
Query: 586 AGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAG 645
A +A MV VFC RLGWH+ E L+++FQ+R+SFGV+ E+ +L I + RAR LY +G
Sbjct: 699 ASTYAGMVTVFCNRLGWHNLELLLSQFQSRLSFGVQRELCDLVRISLLTAQRARTLYSSG 758
Query: 646 LRTPLAIAEASIPELVKAL-----FESSSWGTEGSAQRSLQFGVAKKIKNGARKIVLDK- 699
T +A A + E+ KAL F+SS + S + + + I +K + ++
Sbjct: 759 FVTVAELARADVSEVEKALRKAIPFKSSRQAVDESEVEAQERKSMRCIWVSGKKALTERE 818
Query: 700 -----AEEARIAAFSAFKSLGYDVPQFAPPISTAVCNSIRKEVGSSSGSDTADTSHS--- 751
EA++ LG + P T NS + + S + T H
Sbjct: 819 AAQQIVAEAQLLLQKDLALLGVEWSPACLPAKTQPDNSSTVKSNTEPRSMSGGTEHEGDQ 878
Query: 752 -----------FIDTNHIDNSNVP--ALEKEKDLIKSSD-NGALVSVEGKSDSVMPHSLS 797
++ N +NS+ P LE + K+ D + + S E + D S
Sbjct: 879 DLMSNVTEEKLLLENNSDNNSHPPLRPLESTTNSEKTMDVDSGVSSAECQPDKKCELQSS 938
Query: 798 TVPVVVPSINELSMTSGPAKIPDVTTLSVHLQKQN 832
+ V+ SIN + G V + S LQ++N
Sbjct: 939 VLHKVLKSIN--TKDKGCDNNHTVESSSETLQRRN 971
Score = 100 bits (248), Expect = 5e-19
Identities = 55/129 (42%), Positives = 74/129 (56%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L DYSQ+ELR++AH S+D L+ +L DVF IAA W
Sbjct: 1984 VSMRHAFVPFSGG-LILAVDYSQLELRILAHLSRDRRLLHVLNS-GADVFKSIAAEWKMV 2041
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
SV R+Q K++ YGI+YGMG SL EQM ++A+ I FKS + G+ ++L E
Sbjct: 2042 DPASVDDNMRQQAKQICYGIIYGMGAKSLGEQMGIEENDAACYIETFKSRYNGIQNFLRE 2101
Query: 1334 AVAFCRSKG 1342
V C G
Sbjct: 2102 TVQKCGKNG 2110
Score = 69.7 bits (169), Expect = 8e-10
Identities = 43/118 (36%), Positives = 65/118 (54%), Gaps = 2/118 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL + ++ ++E+P LA +EL GIG + C + ++ +L LE +AY+LAG
Sbjct: 1743 LLEKDGFLDVFKKVEMPTQYCLALLELNGIGFSIAECEAQKHVMQAKLSALESQAYQLAG 1802
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKG-KNHPSTGKHCLDALRVNARDYFVPTQD 1225
+FSL+ P D+A+VLF LKLP P+G G KN + G R+ F T+D
Sbjct: 1803 HSFSLTSPEDVAEVLFLELKLP-PNGDLNGLKNKKTLGYTRRAGARIKLSKQFSTTKD 1859
Score = 49.3 bits (116), Expect = 0.001
Identities = 36/102 (35%), Positives = 51/102 (49%), Gaps = 10/102 (9%)
Query: 1434 VSIHVNIVFLPSTSQGSAADIIKIAMIKIY---SEIFPGVDKLDSSSSVTA------KFE 1484
+ H + +T QGSAADI+K+A I I E FPGV S+ +F
Sbjct: 2132 IKSHAERQAVNTTVQGSAADIVKLATINIQRRIEEAFPGVPTSHQHPSIRLGGRHRNQFR 2191
Query: 1485 MLRDRCRILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSL 1526
LR +LQ+HDEL+ EV V + A +++ ME+ V L
Sbjct: 2192 PLRGGY-FILQLHDELIYEVAEEDVIQVAQIVKREMESVVKL 2232
>ref|XP_221423.3| PREDICTED: similar to DNA polymerase theta [Rattus norvegicus]
Length = 2703
Score = 469 bits (1206), Expect = e-130
Identities = 288/746 (38%), Positives = 403/746 (53%), Gaps = 111/746 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ VAVCTIE+AN LIN
Sbjct: 217 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPTGRFSSLDVAVCTIERANGLIN 276
Query: 62 RLLEEGRLSEMGI-----------------IVIDELHMVGDPKRGYLLELMLTKLRYAAG 104
RL+EE ++ +G +V+DELHM+GD RGYLLEL+LTK+ +
Sbjct: 277 RLIEENKMDLLGFLERCSFVKVNLETLVGTVVVDELHMLGDSHRGYLLELLLTKVCFVTR 336
Query: 105 EGISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEE 164
+ S +D + A +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E
Sbjct: 337 KSASCQADSASA--------LACAVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLE 388
Query: 165 YIKVGNSIYNKSMELSRTIPKGAD--------LGGKDPDHVVELCNEVVQEGQSVLIFCS 216
IKVGNSIY+ SM+L R + D DH+V LC E V++ SVL+FC
Sbjct: 389 SIKVGNSIYDSSMKLVREFQPLLQVKVNYYCYISTGDEDHIVSLCYETVRDNHSVLVFCP 448
Query: 217 SRKGCESTARHVAKFLKSF------TVDINENNCEFAD---ITSAINSLRKCPAGLDPVL 267
S+K CE A +A+ + V +E D + I+ L++ P+GLD VL
Sbjct: 449 SKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVIDQLKRSPSGLDSVL 508
Query: 268 EETFPAGVAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIG 327
+ T P GVAFHHAGLT EER+I+E +R+GL+RVL ATSTL++GVNLPARRVI R P G
Sbjct: 509 KNTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPVFG 568
Query: 328 CDFIDGTRYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCL---SED 384
+D Y QM GRAGR G+DT GES+L+CK E K + LL S P+HSCL E
Sbjct: 569 GQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSLEPVHSCLQSQGEV 628
Query: 385 LNGMTHAILEVVAGGIVQTANDIH---------------RKFLEWNEDT----------- 418
+ M AILE++ G+ T+ D+ ++ ++ N D
Sbjct: 629 TSTMIRAILEIIVSGVASTSQDMQTYAACTFLAADVKEGKQGIQRNRDDVQRGAVDACVT 688
Query: 419 -------------------KLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASD 459
K+Y T LG A+ SSL P ++L + ADL RA +GFVL +D
Sbjct: 689 WLLENEFIQAAEPSDGTGGKVYHPTHLGSATLSSSLSPTDTLDIFADLQRAMKGFVLEND 748
Query: 460 LHLVYLVTPINVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNK 518
LH+VYLVTP+ D DW ++ + KL + V VGV E FL R G +
Sbjct: 749 LHIVYLVTPVFEDWTSIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA--- 805
Query: 519 SRWSNNKRQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGM 578
+ + QH + + + KRF+ +L+L L+ E P+ E+ + + RG
Sbjct: 806 ------RTERQH-----------RQMAIHKRFFTSLVLLDLISEIPLKEINQKYGCNRGQ 848
Query: 579 VQGLQENAGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRA 638
+Q LQ++A +A M+ VF RLGWH+ E L+++FQ R++FG++ E+ +L + + RA
Sbjct: 849 IQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLIRVSSLNAQRA 908
Query: 639 RALYKAGLRTPLAIAEASIPELVKAL 664
R LY +G T +A A E+ AL
Sbjct: 909 RFLYASGFLTVADLARADTVEVEAAL 934
Score = 99.4 bits (246), Expect = 9e-19
Identities = 51/115 (44%), Positives = 72/115 (62%), Gaps = 1/115 (0%)
Query: 1228 LLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTK 1287
L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W +VG R+Q K
Sbjct: 2438 LILAADYSQLELRILAHLSRDCRLIQVLNS-GADVFRSIAAEWKMIEPDAVGDNLRQQAK 2496
Query: 1288 KMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ + V CR G
Sbjct: 2497 QICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYKGINHFMRDTVKNCRRDG 2551
Score = 60.1 bits (144), Expect = 6e-07
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
+L E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2124 MLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECETQKHIMQAKLDAIETQAYQLAG 2183
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNK 1197
+FS + DIA+VLF LKLP P+G+ K
Sbjct: 2184 HSFSFTSADDIAQVLFLELKLP-PNGEMK 2211
>emb|CAI56770.1| hypothetical protein [Homo sapiens]
Length = 2149
Score = 468 bits (1205), Expect = e-130
Identities = 275/673 (40%), Positives = 388/673 (56%), Gaps = 89/673 (13%)
Query: 48 VAVCTIEKANSLINRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGI 107
+AVCTIE+AN LINRL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y +
Sbjct: 15 IAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSA 74
Query: 108 SKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIK 167
S +D S ++ +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +K
Sbjct: 75 SCQADLASSLSNA--------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVK 126
Query: 168 VGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARH 227
VGNSIY+ SM+L R + G D DHVV LC E + + SVL+FC S+K CE A
Sbjct: 127 VGNSIYDSSMKLVREFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADI 185
Query: 228 VAKFLKSFTVD----INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFH 278
+A+ + + + C E ++ ++ LR+ P+GLD VL++T P GVAFH
Sbjct: 186 IAREFYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFH 245
Query: 279 HAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQ 338
HAGLT EER+I+E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y Q
Sbjct: 246 HAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQ 305
Query: 339 MAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAIL 393
M GRAGR G+DT GES+LICK E K + LL S P+ SCL E++ G M AIL
Sbjct: 306 MVGRAGRKGVDTVGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAIL 365
Query: 394 EVVAGGIVQTANDIH----------------------------------------RKFLE 413
E++ GG+ T+ D+H +F++
Sbjct: 366 EIIVGGVASTSQDMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQ 425
Query: 414 WNE-----DTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTP 468
E + K+Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP
Sbjct: 426 STEASDGTEGKVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTP 485
Query: 469 INVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQ 527
+ D DW ++ + KL + V VGV E FL R G + + +
Sbjct: 486 MFEDWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTE 536
Query: 528 NQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAG 587
QH + + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A
Sbjct: 537 RQH-----------RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAA 585
Query: 588 RFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLR 647
+A M+ VF RLGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G
Sbjct: 586 VYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFH 645
Query: 648 TPLAIAEASIPEL 660
T +A A+I E+
Sbjct: 646 TVADLARANIVEV 658
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 1817 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 1873
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 1874 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 1933
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 1934 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 1986
>ref|XP_545125.1| PREDICTED: similar to DNA polymerase theta isoform 1 [Canis
familiaris]
Length = 2639
Score = 449 bits (1156), Expect = e-124
Identities = 274/726 (37%), Positives = 393/726 (53%), Gaps = 92/726 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G +V Y G+ +AVCTIE+AN LIN
Sbjct: 250 ALFILPFVSVAKEKKYYLQSLFQEIGINVDGYMGSTSPTGHFSSLDIAVCTIERANGLIN 309
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D
Sbjct: 310 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITHKSASCQADLA------- 362
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+ + +QIVGMSAT+PN+ VA WL A LY T FRPVPL E +K+GNSIY+ SM+L R
Sbjct: 363 -SPLSNAVQIVGMSATLPNLEIVASWLNAELYHTNFRPVPLLESVKIGNSIYDSSMKLVR 421
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DHVV LC E + + SVLIFC S+K CE A +A +
Sbjct: 422 EFQPNLQVKG-DEDHVVSLCYETICDNHSVLIFCPSKKWCEKLADIIACEFYNLHHQATG 480
Query: 236 ---TVDINENNCEFADITSAINSLRKCPAGLDPV---LEETFPAGVAFHHAGLTVEEREI 289
+ ++ E + ++ L++ P+GLD V L F GLT EER+I
Sbjct: 481 LVRSSELPPVVLEQKGLLEVMDQLKRSPSGLDSVRQVLATVILCYFLFILQGLTFEERDI 540
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
+E +R+G +RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+D
Sbjct: 541 IEGAFRQGQIRVLAATSTLSSGVNLPARRVIIRTPIFGGQPLDILTYKQMVGRAGRKGVD 600
Query: 350 TKGESVLICKPQELKKVMGLLNESCPPLHSCL-----SEDLNGMTHAILEVVAGGIVQTA 404
T GES+L+CK E K + LL S P+ SCL E M AILE++ GG+ T+
Sbjct: 601 TVGESILVCKNSEKSKGIALLQGSLKPVRSCLQRQKGEEVTASMIRAILEIIVGGVASTS 660
Query: 405 ND----------------------------------------IHRKFLEWNE-----DTK 419
D + +F++ E +
Sbjct: 661 QDMQTYASCTFLAASMKEGKLGSQKNQDCVQLGAIEACVMWLLENEFIQITETGDGTEGT 720
Query: 420 LYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWE 478
+Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D DW
Sbjct: 721 VYHPTHLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPMFEDWATIDWY 780
Query: 479 SYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVN 538
++ + KL + V VGV E FL R G + + + QH
Sbjct: 781 RFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-------- 823
Query: 539 SDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCE 598
+ + + KRF+ +L+L L+ E P+ E+ + + +RG +Q LQ++A +A M+ VF
Sbjct: 824 ---RQMAIHKRFFTSLVLLDLISEVPLKEINQKYGCSRGQIQSLQQSAAVYAGMITVFSN 880
Query: 599 RLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIP 658
RLGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I
Sbjct: 881 RLGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARFLYASGFLTVADLARANIA 940
Query: 659 ELVKAL 664
E+ L
Sbjct: 941 EVEAVL 946
Score = 102 bits (253), Expect = 1e-19
Identities = 57/129 (44%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S D LI++L DVF IAA W
Sbjct: 2361 VSMRHAFVPFSGG-LILAADYSQLELRILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMI 2418
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
SVG R+Q K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ E
Sbjct: 2419 EPESVGDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIESFKSRYTGINHFMRE 2478
Query: 1334 AVAFCRSKG 1342
V C+ G
Sbjct: 2479 TVKNCKRNG 2487
Score = 62.4 bits (150), Expect = 1e-07
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Query: 1038 DMCIVAWILWPDEESSS-----SPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGC 1092
D + W+L PD + + S L E+ E G N +
Sbjct: 2036 DPKVACWLLDPDSKEPTLHSIVSSFLPHELLLLEGIETGQGIQSLGLNVNTEHSGRYRAS 2095
Query: 1093 CRRVAQTRALCSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLL 1152
+ A+ + L LL E L + ++E+P LA +EL GIG C + ++
Sbjct: 2096 VESILAFNAM-NQLNSLLKKENLQDVFCKVEMPSQYCLALLELNGIGFSTTECESQKHIM 2154
Query: 1153 VKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+L +E +AY+LAG +FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 2155 QAKLDAIEIQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNGEIKNQASKKT 2205
>ref|XP_564726.1| ENSANGP00000027910 [Anopheles gambiae str. PEST]
gi|55245395|gb|EAL41770.1| ENSANGP00000027910 [Anopheles
gambiae str. PEST]
Length = 602
Score = 446 bits (1148), Expect = e-123
Identities = 265/647 (40%), Positives = 372/647 (56%), Gaps = 63/647 (9%)
Query: 18 HLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINRLLEEGRLSEMGIIVI 77
+L+ LLEP G V +YG + +AVCTIEKANS++NRLLE+ L+ +G++V+
Sbjct: 1 YLKDLLEPGGMRVEGFYGGYHPPGGFESVDLAVCTIEKANSIVNRLLEQSALTTLGLVVV 60
Query: 78 DELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDKNDPAQGLQIVGMSAT 137
DE H++ DP RGY+LEL+LTK+R+ A + +QIV MSAT
Sbjct: 61 DEAHLISDPGRGYILELLLTKIRFVAARCEHR-------------------IQIVCMSAT 101
Query: 138 MPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRTIPKGADLG---GKDP 194
+PN+ +A WL+A LY T+FRP+ L E +KVGN+IY+ S E R + KG G KD
Sbjct: 102 LPNIDLLARWLEADLYHTDFRPIALVEMLKVGNTIYSASGEAIRYL-KGTLHGYTVPKDA 160
Query: 195 DHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDINENNCEFADITSAIN 254
DHV LC E + +G +V++FC S+ CE A +A L + + + ++ + ++
Sbjct: 161 DHVALLCLETILDGCAVIVFCPSKDWCEQLAISLASTLHTLRKENHPHDELRRRLREQLD 220
Query: 255 S---------LRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKGLLRVLTAT 305
LR CPAGLD VLE+T GVAFHHAGLT +ER+I+E +R G LR++ AT
Sbjct: 221 GERQEEVLLQLRNCPAGLDSVLEKTVRYGVAFHHAGLTTDERDIIEGSFRDGALRIIVAT 280
Query: 306 STLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLICKPQELKK 365
STL++GVNLPARRVI R P+ G + Y QM GRAGRTG DT GES+LIC P E K
Sbjct: 281 STLSSGVNLPARRVIVRTPKFGGKPMSSLTYKQMIGRAGRTGRDTLGESILICTPAEEKI 340
Query: 366 VMGLLNESCPPLHSCL-SEDLNGMTHAILEVVAGGIVQTANDIHRKFLEWN--EDTKLYS 422
L+ PP+ SCL SE+ + AILE++A G T ++ F+ D + S
Sbjct: 341 GRELIGAELPPVRSCLDSENYAHLKRAILEIIASGSATTTQEL-ETFVNATLYIDQTVLS 399
Query: 423 TTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWES 479
T LG+A +SL P++ ++ ++L RAR+ FVL S+LH +YLVTP +V + DW
Sbjct: 400 ATRLGQACLSASLPPKDGFLLFSELQRARQCFVLESELHAIYLVTPYSVAYQWQQIDWMD 459
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
+ + + KL + VG VGV E F++R G N
Sbjct: 460 FLDLWEKLPSASKRVGELVGVKESFMVRAMRGA------------------------ANL 495
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
D +TL++ KRFY AL L LV E P+ V FK RG++Q LQ+ + FA +V FC
Sbjct: 496 DYRTLQIHKRFYTALALLDLVNEVPLCTVARRFKCCRGLLQSLQQVSSTFAGIVTSFCAS 555
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGL 646
L W + LVA+F+ R+ FGV E+++L IP + G RAR L+ +G+
Sbjct: 556 LNWTLLQLLVAQFRERLFFGVAHELLDLMRIPSLNGQRARLLHDSGI 602
>ref|XP_308346.2| ENSANGP00000019077 [Anopheles gambiae str. PEST]
gi|55245396|gb|EAA04696.3| ENSANGP00000019077 [Anopheles
gambiae str. PEST]
Length = 840
Score = 446 bits (1147), Expect = e-123
Identities = 277/754 (36%), Positives = 402/754 (52%), Gaps = 112/754 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+L+LP+V++ EK +L+ LLEP G V +YG + +AVCTIEKANS++N
Sbjct: 87 AMLILPFVAVAREKMLYLKDLLEPGGMRVEGFYGGYHPPGGFESVDLAVCTIEKANSIVN 146
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RLLE+ L+ +G++V+DE H++ DP RGY+LEL+LTK+R+ A +
Sbjct: 147 RLLEQSALTTLGLVVVDEAHLISDPGRGYILELLLTKIRFVAARCEHR------------ 194
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIV MSAT+PN+ +A WL+A LY T+FRP+ L E +KVGN+IY+ S E R
Sbjct: 195 -------IQIVCMSATLPNIDLLARWLEADLYHTDFRPIALVEMLKVGNTIYSASGEAIR 247
Query: 182 TIPKGADLG---GKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD 238
+ KG G KD DHV LC E + +G +V++FC S+ CE A +A L + +
Sbjct: 248 YL-KGTLHGYTVPKDADHVALLCLETILDGCAVIVFCPSKDWCEQLAISLASTLHTLRKE 306
Query: 239 INENNCEFADITSAINS---------LRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREI 289
+ ++ + ++ LR CPAGLD VLE+T GVAFHHAGLT +ER+I
Sbjct: 307 NHPHDELRRRLREQLDGERQEEVLLQLRNCPAGLDSVLEKTVRYGVAFHHAGLTTDERDI 366
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
+E +R G LR++ ATSTL++GVNLPARRVI R P+ G + Y QM GRAGRTG D
Sbjct: 367 IEGSFRDGALRIIVATSTLSSGVNLPARRVIVRTPKFGGKPMSSLTYKQMIGRAGRTGRD 426
Query: 350 TKGESVLICKPQELKKVMGLLNESCPPLHSCL-SEDLNGMTHAILEVVAGGIVQTANDIH 408
T GES+LIC P E K L+ PP+ SCL SE+ + AILE++A G T ++
Sbjct: 427 TLGESILICTPAEEKIGRELIGAELPPVRSCLDSENYAHLKRAILEIIASGSATTTQELE 486
Query: 409 R-------------KFLEWNEDT------------------------------------- 418
+ + NE+T
Sbjct: 487 TFVNATLSKKLPTGEEEDENEETDPIVSCISFLLEYEFIRCLQQDIVEEDGSTTATPKST 546
Query: 419 --KLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV--- 473
+ S T LG+A +SL P++ ++ ++L RAR+ FVL S+LH +YLVTP +V
Sbjct: 547 KRTVLSATRLGQACLSASLPPKDGFLLFSELQRARQCFVLESELHAIYLVTPYSVAYQWQ 606
Query: 474 EPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMS 533
+ DW + + + KL + VG VGV E F++R G
Sbjct: 607 QIDWMDFLDLWEKLPSASKRVGELVGVKESFMVRAMRGA--------------------- 645
Query: 534 SGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMV 593
N D +TL++ KRFY AL L LV E P+ V FK RG++Q LQ+ + FA +V
Sbjct: 646 ---ANLDYRTLQIHKRFYTALALLDLVNEVPLCTVARRFKCCRGLLQSLQQVSSTFAGIV 702
Query: 594 AVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIA 653
FC L W + LVA+F+ R+ FGV E+++L IP + G RAR L+ +G+ + +A
Sbjct: 703 TSFCASLNWTLLQLLVAQFRERLFFGVAHELLDLMRIPSLNGQRARLLHDSGITGLVQLA 762
Query: 654 EASIPELVKALFESSSWGTEGSAQRSLQFGVAKK 687
+ + L +S+ E + ++ ++
Sbjct: 763 NSDRLAVETILHHRTSFEAERVRENENEYDAERR 796
>ref|XP_416549.1| PREDICTED: similar to DNA polymerase theta isoform 1; polymerase
(DNA-directed), theta [Gallus gallus]
Length = 3066
Score = 446 bits (1146), Expect = e-123
Identities = 277/775 (35%), Positives = 399/775 (50%), Gaps = 140/775 (18%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + + V Y G+ VAVCTIEKAN LIN
Sbjct: 542 ALFILPFVSVAKEKKCYLQALFQEVDMRVGGYMGSISPAGRFSLLDVAVCTIEKANGLIN 601
Query: 62 RLLEEGRLSEM----------------------------------------GIIVIDELH 81
RL+EE ++ + ++V +L+
Sbjct: 602 RLIEENQMDSLVPCVTGMTYRKSEHFFFIQSISDLDFGIQSWLFCVAQWQKSVLVELQLY 661
Query: 82 MVG------------------DPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDKN 123
VG D RGYLLEL+LTK+RY + + + + G
Sbjct: 662 FVGYGRQSVGVVVVDELHMLGDSHRGYLLELLLTKVRYITEKAAKRKTKMKSPGFG---- 717
Query: 124 DPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRTI 183
G+Q+VGMSAT+PN+ +A WL A LY T+FRPVPL+E++K+GN+IY+ SM L R
Sbjct: 718 ----GIQVVGMSATLPNLGLLASWLDAELYCTDFRPVPLKEWVKIGNNIYDSSMNLVREF 773
Query: 184 PKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDINENN 243
L G D DHVV LC E V +G SVL+FC S+ CE A +A+ + +++ E
Sbjct: 774 QPKLQLKG-DEDHVVSLCYETVCDGHSVLLFCPSKNWCEKLADIIAR--EFYSLQQAEIV 830
Query: 244 CEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKGLLRVLT 303
+ I ++ LR+ +GLD VL+ T P GVAFHHAGLT +ER+I+E +R+ +RVL
Sbjct: 831 VDREGIDEVLDQLRRSLSGLDSVLQRTLPWGVAFHHAGLTFDERDIIEGAFRQSTIRVLA 890
Query: 304 ATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLICKPQEL 363
ATSTL++GVNLPARRVI R P G +D Y QMAGRAGR G+DT+GES+L+CKP E
Sbjct: 891 ATSTLSSGVNLPARRVIIRTPMFGGTLLDVLTYKQMAGRAGRKGVDTEGESILVCKPSER 950
Query: 364 KKVMGLLNESCPPLHSCLSED-----LNGMTHAILEVVAGGIVQTANDIHR--------- 409
K LL S P+ SCL + M AILE++ G+ T +D+
Sbjct: 951 SKGTALLQGSLKPVRSCLLRKEGEGVASSMKRAILEIIVSGVANTPDDVQTYASCTLLAS 1010
Query: 410 ----------------------------------KFLEWNED--TKLYSTTPLGRASFGS 433
+ LE +D K++ T LG A+ S
Sbjct: 1011 SLKDNKRENEKEQDKVQTGPIEACIAWLLENEFIQVLERADDKKAKIFHPTHLGSATLSS 1070
Query: 434 SLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYERFVKLSPLDQ 492
SL P E++ + +DL RA + FVL +DLH+VYLVTP+ D DW ++ + KL +
Sbjct: 1071 SLSPTEAMEIFSDLQRAMKSFVLENDLHIVYLVTPVYEDWTTIDWYQFFCLWEKLPASMK 1130
Query: 493 SVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTLRVCKRFYV 552
V VG+ E FL R G + ++ + + + KRF+
Sbjct: 1131 RVAELVGIEEGFLARSVKGKITAKTEKQY--------------------RQMAIHKRFFT 1170
Query: 553 ALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHDFEGLVAKF 612
+L L L+ E P+ ++ + + +RG +Q LQ++A +A MV VFC RLGWH+ E L+++F
Sbjct: 1171 SLALLDLISEVPLKDMTKKYGCSRGQLQSLQQSAATYAGMVTVFCNRLGWHNMELLLSQF 1230
Query: 613 QNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKALFES 667
Q+R++FGV E+ +L + + RAR LY AG T +A+AS ++ AL S
Sbjct: 1231 QSRLTFGVHRELCDLVRVSLLNAQRARMLYNAGFVTVADLAKASPGDVATALKNS 1285
Score = 121 bits (303), Expect = 2e-25
Identities = 111/385 (28%), Positives = 157/385 (39%), Gaps = 131/385 (34%)
Query: 1220 FVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVG 1279
F+ Q +L ADY Q+ELR++AHFS+D LIE K DVF IAA W +VG
Sbjct: 2793 FLYRQSGGFILAADYCQLELRILAHFSRDCRLIEAFNK-GADVFKSIAAEWKMIDSEAVG 2851
Query: 1280 SRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCR 1339
R+Q K++ YGI+YG+G SL EQM ++A+ I +FKS + G+ +L E V+ CR
Sbjct: 2852 DSTRQQAKQICYGIIYGIGAKSLGEQMGIDDNKAANYIESFKSRYTGIQKFLKETVSNCR 2911
Query: 1340 SKG*GDLVPFLHFVYAFLLNLNYLWAVCNLIMCKYIHDPDM*RLSREGNDFCQK*NLAVV 1399
G FV L YL A+ R+ N
Sbjct: 2912 RDG---------FVQTILGRRRYLPAI------------------RDSN----------- 2933
Query: 1400 QKNQKLRGKLSIPFVRCNTLFSFSSKSGYVSLQAVSIHVNIVFLPSTSQGSAADIIKIAM 1459
P+++ + QAV+ +T QGSAADI+K A
Sbjct: 2934 ------------PYIK-----------AHAERQAVN---------TTVQGSAADIVKTAT 2961
Query: 1460 IKIYS--EIFPGVDK----LDSSSSVTAKFEMLRDRCR----------ILLQVHDELVLE 1503
+ I E V+K L++S + R R R +LQ+HDEL+ E
Sbjct: 2962 VNIQRRLEALSSVNKSHGHLENSFQRDKTGRLSRKRNREMLHPISGGFFILQLHDELLYE 3021
Query: 1504 VDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIF 1563
V V + A +++ MENAV L
Sbjct: 3022 VAEDDVIQVAQIVKHEMENAVKL------------------------------------- 3044
Query: 1564 TVYAYASAVPLNVKLKVGRTWGSLE 1588
+V LNVK+K+G +WG L+
Sbjct: 3045 -------SVKLNVKVKIGPSWGELQ 3062
Score = 61.2 bits (147), Expect = 3e-07
Identities = 36/105 (34%), Positives = 62/105 (58%), Gaps = 3/105 (2%)
Query: 1089 HNGCCRRVAQTRALCSVLWKL---LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGC 1145
H+G R ++ + +++ +L L E L + ++E+P LA +EL GIG
Sbjct: 2492 HSGRYRAAIESVLIFNIMNQLHSELRKENLTDVFSKVEMPNHYCLALLELNGIGFSTAAY 2551
Query: 1146 IQARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLP 1190
++++ +L ++E +AY+LAG +FSL+ P D+A+VLF LKLP
Sbjct: 2552 ETQKQVMQAKLTEIETKAYQLAGHSFSLTSPDDVAEVLFLELKLP 2596
>gb|EAL27595.1| GA19301-PA [Drosophila pseudoobscura]
Length = 2029
Score = 431 bits (1109), Expect = e-119
Identities = 264/726 (36%), Positives = 376/726 (51%), Gaps = 101/726 (13%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINR 62
+++LP++S+ EK +L+ LL P G V ++G VA+CTIEKANS++N+
Sbjct: 257 LVILPFISVVREKTSYLQDLLTPAGHRVEGFFGGYTPPGGFDSIDVAICTIEKANSIVNK 316
Query: 63 LLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDK 122
L+E+G+L +G +V+DE+H++ + RGY+LEL+L K+ Y S K
Sbjct: 317 LMEQGKLGVIGTVVVDEVHLISEKGRGYILELLLAKILYM-----------------SRK 359
Query: 123 NDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRT 182
N A +Q++ MSAT+ NV + WL A LY T +RPV L+E IKVG IY+ +E R
Sbjct: 360 N--ALQIQVITMSATLANVELLRRWLDAELYITNYRPVALQEMIKVGTKIYDHHLEFQRD 417
Query: 183 IPKGADLG--GKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDIN 240
I + +++ D DHV +LC E + EG SV++FC SR CES A +A +
Sbjct: 418 ITQQSEVPCLTNDSDHVAQLCIETLLEGCSVIVFCPSRDWCESLAVQLAIAIHGLIKSGT 477
Query: 241 E------NNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCY 294
E +N I LR P GLD + + AFHHAGLT EER+IVE C+
Sbjct: 478 ELSRRLRSNLNPEAIEDVKQQLRDIPTGLDSTMSKAVTYACAFHHAGLTTEERDIVEACF 537
Query: 295 RKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGES 354
+ G L+VL ATSTL++GVNLPARRVI R P G + + Y QM GRAGRTG DT GES
Sbjct: 538 KAGALKVLVATSTLSSGVNLPARRVIIRSPLFGKNQMSSLTYRQMIGRAGRTGKDTLGES 597
Query: 355 VLICKPQELKKVMGLLNESCPPLHSCLS-EDLNGMTHAILEVVAGGIVQTANDIH----- 408
+LIC + L+ P+ SCL ++ + A+LEV++ G+ T +I
Sbjct: 598 ILICTESNQRVGRDLVQAQLQPISSCLEMDESTHLKRALLEVISAGVASTRQEIDSFVNC 657
Query: 409 -----------------------------------------RKFLEWNEDTKLYSTTPLG 427
R ++ T Y T LG
Sbjct: 658 TLLSAEKAMAKLSEEQQQGAEDCSSHFIDDVLDFLVDYEFIRHQVDEEAGTANYVGTHLG 717
Query: 428 RASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWESYYERF 484
A SS+ P + LI+ A+L +AR FVL +DLH VYLVTP +V + DW Y + +
Sbjct: 718 AACLASSMPPGDGLILFAELQKARRTFVLDTDLHAVYLVTPYSVCYQLQDLDWLLYLDMW 777
Query: 485 VKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTL 544
KLSP + VG VGV E FL+R G D + +
Sbjct: 778 EKLSPAMKRVGELVGVKEAFLIRAMRGQS------------------------KLDYKQM 813
Query: 545 RVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHD 604
++ KRFY AL L L+ ETP+ V FK RG++QGLQ+ + FA +V FC+ L W
Sbjct: 814 QIHKRFYTALALKELINETPIHVVAHKFKCNRGVLQGLQQISSTFAGIVTAFCKSLKWST 873
Query: 605 FEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
+V +F++R+ FG+ ++++L +P + RARA+Y AG T + +A A L K L
Sbjct: 874 IALIVEQFKDRLFFGIHIDLIDLMQLPDLSQKRARAIYDAGFTTVVELAGADALVLEKVL 933
Query: 665 FESSSW 670
+ S S+
Sbjct: 934 YNSLSF 939
Score = 109 bits (272), Expect = 9e-22
Identities = 92/384 (23%), Positives = 158/384 (40%), Gaps = 92/384 (23%)
Query: 1044 WILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMR-------------KAAHN 1090
W+L P++ S K + ++ +PE A AN CG R +A+
Sbjct: 1525 WLLEPEKTFSF-----KNMCQQFAPECTALANLCGSGRGYSSHGLDSSSAILPKLRASIE 1579
Query: 1091 GCCR-----------RVAQTRALCSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIG 1139
C + + ++L+ LL L+ E+E+P+ VL ME G
Sbjct: 1580 ACVTVHILKGQIENLERIEASGMFNMLY-LLSYLFLICCFTEVEMPIQIVLCRMECVGFP 1638
Query: 1140 VDLEGCIQARKLLVKRLKQLEKEAYKLAGMTFSLS------------------------- 1174
+ + K ++ L ++E + YK+ G F+L
Sbjct: 1639 AKHQRMGRLIKHMLDTLNKVEIKIYKMHGSKFNLGSTQAVANVLGLHRKPHGRVSTSRQV 1698
Query: 1175 ---MPADIAKVLFEHLKLPIPDGKNKGK---------------NHPSTGKHCL------- 1209
+ + I++++ H KL + K H +TG+ +
Sbjct: 1699 LEKLGSPISELILNHRKLNMQIVKGMQPLIRCCKANRIHGHSITHTATGRISMSEPNLQN 1758
Query: 1210 -----------DALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKP 1258
D++R++ R F + LL+AD+ Q+E+R++AH S+D L+ ++ P
Sbjct: 1759 VAKDFDIRMGPDSVRISCRSVFKSMDEKRCLLSADFCQLEMRILAHLSQDKALVSVMNSP 1818
Query: 1259 DGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERIS 1318
D+FT IAA W PE V + R TK++ YGI+YGMG SL + + CT EA
Sbjct: 1819 Q-DLFTAIAAHWNHIPEAEVTEQMRSGTKQICYGIVYGMGMRSLGDALQCTESEAQLICE 1877
Query: 1319 NFKSTFPGVASWLHEAVAFCRSKG 1342
F ++PG+ ++ + + F R G
Sbjct: 1878 QFHQSYPGIRAYTEKVLKFARKLG 1901
Score = 36.6 bits (83), Expect = 7.1
Identities = 36/143 (25%), Positives = 54/143 (37%), Gaps = 52/143 (36%)
Query: 1445 STSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEV 1504
+T QGSAADI K A++ + I K + + +++L +HDELV EV
Sbjct: 1934 TTIQGSAADIAKRAILDMDKNI----------GRYWKKLGVEENSIQLVLHIHDELVYEV 1983
Query: 1505 DPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIFT 1564
+ K A L +ME+ +G L
Sbjct: 1984 PEAKAKRIAKFLGLTMES----IGKGKL-------------------------------- 2007
Query: 1565 VYAYASAVPLNVKLKVGRTWGSL 1587
VPL VK+K+G +WG +
Sbjct: 2008 ------TVPLKVKIKMGESWGEM 2024
>gb|AAF54858.1| CG6019-PA [Drosophila melanogaster] gi|17933644|ref|NP_524333.1|
CG6019-PA [Drosophila melanogaster]
gi|7511999|pir||T13858 probable DNA-directed DNA
polymerase (EC 2.7.7.7) I - fruit fly (Drosophila
melanogaster) gi|2340084|gb|AAB67306.1| mus308
[Drosophila melanogaster]
Length = 2059
Score = 422 bits (1085), Expect = e-116
Identities = 267/726 (36%), Positives = 379/726 (51%), Gaps = 103/726 (14%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINR 62
+L+LP++S+ EK +++ LL P G V +YG + VA+CTIEKANS++N+
Sbjct: 282 LLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVNK 341
Query: 63 LLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDK 122
L+E+G+L +G++V+DE+H++ D RGY+LEL+L K+ Y +
Sbjct: 342 LMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRN---------------- 385
Query: 123 NDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRT 182
+Q++ MSAT+ NV + WL A LY T +RPV L+E IKVG IY+ ++L R
Sbjct: 386 ---GLQIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRD 442
Query: 183 IPKGADLGG---KDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFL----KSF 235
+ K L D D V LC E + EG SV++FC S+ CE+ A +A + KS
Sbjct: 443 VAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSE 502
Query: 236 TV--DINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETC 293
TV N I LR P GLD V+ + AFHHAGLT EER+I+E
Sbjct: 503 TVLGQRLRTNLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEAS 562
Query: 294 YRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGE 353
++ G L+VL ATSTL++GVNLPARRV+ R P G + Y QM GRAGR G DT GE
Sbjct: 563 FKAGALKVLVATSTLSSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGKDTLGE 622
Query: 354 SVLICKPQELKKVMGLLNESCPPLHSCLSEDLNGMTH---AILEVVAGGIVQTANDI--- 407
S+LIC + L+ P+ SCL D++G TH A+LEV++ G+ T DI
Sbjct: 623 SILICNEINARMGRDLVVSELQPITSCL--DMDGSTHLKRALLEVISSGVANTKEDIDFF 680
Query: 408 ------------HRK--------------------------FLEWNE--DTKLYSTTPLG 427
H K L+ NE +T +Y T LG
Sbjct: 681 VNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYEFVRLQRNEERETAVYVATRLG 740
Query: 428 RASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWESYYERF 484
A SS+ P + LI+ A+L ++R FVL S+LH VYLVTP +V + DW Y +
Sbjct: 741 AACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMW 800
Query: 485 VKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTL 544
KLS + VG VGV + FL + G D + +
Sbjct: 801 EKLSSPMKKVGELVGVRDAFLYKALRGQ------------------------TKLDYKQM 836
Query: 545 RVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHD 604
++ KRFY+AL L LV ETP+ V +K RGM+Q LQ+ A FA +V FC L W
Sbjct: 837 QIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFCNSLQWST 896
Query: 605 FEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
+V++F++R+ FG+ ++++L IP + RARAL+ AG+ + + +A A EL K L
Sbjct: 897 LALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKVL 956
Query: 665 FESSSW 670
+ S S+
Sbjct: 957 YNSISF 962
Score = 104 bits (259), Expect = 3e-20
Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 1/133 (0%)
Query: 1210 DALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAAR 1269
D + ++ R F+PT ++ LL+AD+ Q+E+R++AH S+D L+E++ K D+F IAA
Sbjct: 1802 DVVHISCRSPFMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVM-KSSQDLFIAIAAH 1860
Query: 1270 WIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVAS 1329
W E V R TK++ YGI+YGMG SLAE ++C+ EA F + G+
Sbjct: 1861 WNKIEESEVTQDLRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRD 1920
Query: 1330 WLHEAVAFCRSKG 1342
+ V F RSKG
Sbjct: 1921 YTTRVVNFARSKG 1933
Score = 47.0 bits (110), Expect = 0.005
Identities = 39/144 (27%), Positives = 57/144 (39%), Gaps = 54/144 (37%)
Query: 1445 STSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEV 1504
ST QGSAADI K A++K+ I +KL + +++ +HDEL+ EV
Sbjct: 1966 STIQGSAADIAKNAILKMEKNIERYREKLALGDNSVD----------LVMHLHDELIFEV 2015
Query: 1505 DPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIFT 1564
K+ A +L +MEN V L
Sbjct: 2016 PTGKAKKIAKVLSLTMENCVKL-------------------------------------- 2037
Query: 1565 VYAYASAVPLNVKLKVGRTWGSLE 1588
+VPL VKL++GR+WG +
Sbjct: 2038 ------SVPLKVKLRIGRSWGEFK 2055
Score = 40.8 bits (94), Expect = 0.38
Identities = 43/186 (23%), Positives = 72/186 (38%), Gaps = 25/186 (13%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKA--AHNGCCRR 1095
D + W+L PD+ + + + +PE AN CG R + R
Sbjct: 1563 DAKVANWLLQPDKTVNFL-----NMCQTFAPECTGLANLCGSGRGYSSYGLDTSSAILPR 1617
Query: 1096 VAQTRALCSVLWKL---------LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCI 1146
+ C L L + + L++ +IE+P+ L MEL G +
Sbjct: 1618 IRTAIESCVTLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQMELVGFPAQKQRLQ 1677
Query: 1147 QARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGK 1206
Q + +V +K++E + Y+ G F+L +AKVL H K K +T +
Sbjct: 1678 QLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLH---------RKAKGRVTTSR 1728
Query: 1207 HCLDAL 1212
L+ L
Sbjct: 1729 QVLEKL 1734
>gb|AAX33507.1| LP14642p [Drosophila melanogaster]
Length = 2059
Score = 422 bits (1085), Expect = e-116
Identities = 267/726 (36%), Positives = 379/726 (51%), Gaps = 103/726 (14%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINR 62
+L+LP++S+ EK +++ LL P G V +YG + VA+CTIEKANS++N+
Sbjct: 282 LLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVNK 341
Query: 63 LLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDK 122
L+E+G+L +G++V+DE+H++ D RGY+LEL+L K+ Y +
Sbjct: 342 LMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRN---------------- 385
Query: 123 NDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRT 182
+Q++ MSAT+ NV + WL A LY T +RPV L+E IKVG IY+ ++L R
Sbjct: 386 ---GLQIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRD 442
Query: 183 IPKGADLGG---KDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFL----KSF 235
+ K L D D V LC E + EG SV++FC S+ CE+ A +A + KS
Sbjct: 443 VAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSE 502
Query: 236 TV--DINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETC 293
TV N I LR P GLD V+ + AFHHAGLT EER+I+E
Sbjct: 503 TVLGQRLRTNLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEAS 562
Query: 294 YRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGE 353
++ G L+VL ATSTL++GVNLPARRV+ R P G + Y QM GRAGR G DT GE
Sbjct: 563 FKAGALKVLVATSTLSSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGKDTLGE 622
Query: 354 SVLICKPQELKKVMGLLNESCPPLHSCLSEDLNGMTH---AILEVVAGGIVQTANDI--- 407
S+LIC + L+ P+ SCL D++G TH A+LEV++ G+ T DI
Sbjct: 623 SILICNEINARMGRDLVVSELQPITSCL--DMDGSTHLKRALLEVISSGVANTKEDIDFF 680
Query: 408 ------------HRK--------------------------FLEWNE--DTKLYSTTPLG 427
H K L+ NE +T +Y T LG
Sbjct: 681 VNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYEFVRLQRNEERETAVYVATRLG 740
Query: 428 RASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWESYYERF 484
A SS+ P + LI+ A+L ++R FVL S+LH VYLVTP +V + DW Y +
Sbjct: 741 AACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMW 800
Query: 485 VKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTL 544
KLS + VG VGV + FL + G D + +
Sbjct: 801 EKLSSPMKKVGELVGVRDAFLYKALRGQ------------------------TKLDYKQM 836
Query: 545 RVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHD 604
++ KRFY+AL L LV ETP+ V +K RGM+Q LQ+ A FA +V FC L W
Sbjct: 837 QIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFCNSLQWST 896
Query: 605 FEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
+V++F++R+ FG+ ++++L IP + RARAL+ AG+ + + +A A EL K L
Sbjct: 897 LALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKVL 956
Query: 665 FESSSW 670
+ S S+
Sbjct: 957 YNSISF 962
Score = 102 bits (254), Expect = 1e-19
Identities = 51/133 (38%), Positives = 77/133 (57%), Gaps = 1/133 (0%)
Query: 1210 DALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAAR 1269
D + ++ R F+PT ++ LL+AD+ Q+E+R++AH S+D L+E++ K D+F IAA
Sbjct: 1802 DVVHISCRSPFMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVM-KSSQDLFIAIAAH 1860
Query: 1270 WIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVAS 1329
W E V R TK++ YGI+YGMG SLAE ++C+ EA F + G+
Sbjct: 1861 WNKIEESEVTQDLRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRD 1920
Query: 1330 WLHEAVAFCRSKG 1342
+ V F SKG
Sbjct: 1921 YTTRVVNFAHSKG 1933
Score = 47.0 bits (110), Expect = 0.005
Identities = 39/144 (27%), Positives = 57/144 (39%), Gaps = 54/144 (37%)
Query: 1445 STSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEV 1504
ST QGSAADI K A++K+ I +KL + +++ +HDEL+ EV
Sbjct: 1966 STIQGSAADIAKNAILKMEKNIERYREKLALGDNSVD----------LVMHLHDELIFEV 2015
Query: 1505 DPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIFT 1564
K+ A +L +MEN V L
Sbjct: 2016 PTGKAKKIAKVLSLTMENCVKL-------------------------------------- 2037
Query: 1565 VYAYASAVPLNVKLKVGRTWGSLE 1588
+VPL VKL++GR+WG +
Sbjct: 2038 ------SVPLKVKLRIGRSWGEFK 2055
Score = 40.8 bits (94), Expect = 0.38
Identities = 43/186 (23%), Positives = 72/186 (38%), Gaps = 25/186 (13%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKA--AHNGCCRR 1095
D + W+L PD+ + + + +PE AN CG R + R
Sbjct: 1563 DAKVANWLLQPDKTVNFL-----NMCQTFAPECTGLANLCGSGRGYSSYGLDTSSAILPR 1617
Query: 1096 VAQTRALCSVLWKL---------LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCI 1146
+ C L L + + L++ +IE+P+ L MEL G +
Sbjct: 1618 IRTAIESCVTLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQMELVGFPAQKQRLQ 1677
Query: 1147 QARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGK 1206
Q + +V +K++E + Y+ G F+L +AKVL H K K +T +
Sbjct: 1678 QLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLH---------RKAKGRVTTSR 1728
Query: 1207 HCLDAL 1212
L+ L
Sbjct: 1729 QVLEKL 1734
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.320 0.136 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,666,784,000
Number of Sequences: 2540612
Number of extensions: 112495255
Number of successful extensions: 278598
Number of sequences better than 10.0: 1355
Number of HSP's better than 10.0 without gapping: 856
Number of HSP's successfully gapped in prelim test: 499
Number of HSP's that attempted gapping in prelim test: 273084
Number of HSP's gapped (non-prelim): 3447
length of query: 1603
length of database: 863,360,394
effective HSP length: 142
effective length of query: 1461
effective length of database: 502,593,490
effective search space: 734289088890
effective search space used: 734289088890
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 82 (36.2 bits)
Medicago: description of AC127429.13