BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126015.12 - phase: 0
(1620 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
emb|CAC07916.1| putative protein [Arabidopsis thaliana] gi|15231... 593 e-167
ref|XP_475559.1| unknown protein [Oryza sativa (japonica cultiva... 181 2e-43
gb|AAP97166.1| nuclear receptor co-repressor [Homo sapiens] 103 5e-20
gb|AAO32942.1| NCOR isoform b [Homo sapiens] 103 5e-20
emb|CAI35323.1| nuclear receptor co-repressor 1 [Mus musculus] g... 102 1e-19
sp|O75376|NCOR1_HUMAN Nuclear receptor corepressor 1 (N-CoR1) (N... 102 1e-19
gb|AAH50594.1| NCOR1 protein [Homo sapiens] 102 1e-19
gb|AAH56862.1| NCOR1 protein [Homo sapiens] 102 1e-19
gb|AAH58511.1| NCOR1 protein [Homo sapiens] 102 1e-19
ref|XP_577103.1| PREDICTED: nuclear receptor co-repressor 1 [Rat... 102 1e-19
emb|CAI35322.1| nuclear receptor co-repressor 1 [Mus musculus] g... 102 1e-19
emb|CAI35321.1| nuclear receptor co-repressor 1 [Mus musculus] g... 102 1e-19
emb|CAI35320.1| nuclear receptor co-repressor 1 [Mus musculus] g... 102 1e-19
emb|CAI35318.1| nuclear receptor co-repressor 1 [Mus musculus] g... 102 1e-19
dbj|BAA82999.2| KIAA1047 protein [Homo sapiens] 102 1e-19
sp|Q60974|NCOR1_MOUSE Nuclear receptor corepressor 1 (N-CoR1) (N... 102 1e-19
gb|AAH68996.1| NCOR1 protein [Homo sapiens] 102 1e-19
gb|AAC33550.1| nuclear receptor co-repressor N-CoR [Homo sapiens] 102 1e-19
gb|AAH86657.1| Ncor1 protein [Mus musculus] 102 1e-19
gb|AAH94160.1| LOC443635 protein [Xenopus laevis] 102 1e-19
>emb|CAC07916.1| putative protein [Arabidopsis thaliana] gi|15231170|ref|NP_190793.1|
myb family transcription factor [Arabidopsis thaliana]
gi|11358236|pir||T46095 hypothetical protein T25B15.20 -
Arabidopsis thaliana
Length = 1677
Score = 593 bits (1529), Expect = e-167
Identities = 391/1051 (37%), Positives = 580/1051 (54%), Gaps = 79/1051 (7%)
Query: 67 SRRPQDMNNEQRSVDDSPTYSSHPHSDFVNTWEQHNLKDQHAKTG--GVNGLGTGPRCDR 124
+++ D+ +R V D+ + P+++ TWEQ LKD G+N + +C +
Sbjct: 249 AKQCNDLMYGRRLVSDNSLDAPIPNAELEGTWEQLRLKDPQDNNSLHGINDIDGDRKCAK 308
Query: 125 ENSLSSIDWKPLKWTRSGSLSSRGSGFSHSSSSRSMAGTDSYEGKPNLKHKNVTAVESNS 184
E+SL + PL W SGS +S+ SGFSHSSS +S+ DS + K + K VT +S+S
Sbjct: 309 ESSLGATGKLPL-WNSSGSFASQSSGFSHSSSLKSLGAVDSSDRKIEVLPKIVTVTQSSS 367
Query: 185 GEATACVTSSMPSEDATSRKKPRLNWGEGLAKYEKKKVDVPDPGSNKDGSVSSAGNMEPC 244
G+ATAC T++ SE+ +SRKK RL WGEGLAKYEKKKVDV N+DG+ +E
Sbjct: 368 GDATACATTTHLSEEMSSRKKQRLGWGEGLAKYEKKKVDV---NPNEDGTTLMENGLEEL 424
Query: 245 SSISPNLVDKSPKVTGFSDCASPATPSSVACSSSPGVDDKLLGKVGNADNDVSNLTDSPA 304
S++ N+ DKSP D SP TPSSVACSSSPG DK K A +DVSN+ SP+
Sbjct: 425 HSLNKNIADKSPTAAIVPDYGSPTTPSSVACSSSPGFADKSSPKAAIAASDVSNMCRSPS 484
Query: 305 PGFQNHLQKFYLNLDKLDVDSLNSLGSSIVELVQSDDPSSDDSGLVRSNAINKLLIWKAD 364
P HL++F +N+++LD S+ G + EL+ +DD + DS V+ ++N LL WK +
Sbjct: 485 PVSSIHLERFPINIEELDNISMERFGCLLNELLGTDDSGTGDSSSVQLTSMNTLLAWKGE 544
Query: 365 ISKVLEMTESEIDLLENELKSLKSESVDRSECPVASGSQQADSSSKFYEERVEVSQKVIR 424
I K +EMTESEIDLLEN+ ++LK E S V S D + +E+ S
Sbjct: 545 ILKAVEMTESEIDLLENKHRTLKLEGRRHSRV-VGPSSYCCDGDANVPKEQASCSLD--- 600
Query: 425 PVPLKIISSDEPNTVKMP-QSTNLCSIHENDKEEDIDSPGSATSKFVEPLPVNAVSSSYT 483
P SS V+ P L + + E DSPG V+PL +
Sbjct: 601 --PKATASSVAKTLVRAPVHQAGLAKVPADVFE---DSPGE-----VKPL---------S 641
Query: 484 RGYDNLSRDMNAVQSTMMKCFVRCNRKNTSVSACNNVNTPTEVKDSLGDVTFGANLCSSY 543
+ + + R+ + + MK V + +NTP +V+ + +S
Sbjct: 642 QSFATVEREEDILPIPSMKAAV----------SSKEINTPAFANQETIEVSSADDSMASK 691
Query: 544 GDTY-KSIIASNKESANRAHKLFTKLVPKECKKHGNM---GVSNDSFSHTSILQKFAEKK 599
D + ++++NK+ A + +F +L+P++ N G+ F + + +K A++
Sbjct: 692 EDLFWAKLLSANKKYACESSGVFNQLLPRDFNSSDNSRFPGICQTQFD-SHVQEKIADRV 750
Query: 600 QFERFKERVIALKFKALHHLWKEDMRLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
R +E+++ L+FKA WK+D+ L++ K + KS KK EL +K S+R
Sbjct: 751 GLLRAREKILLLQFKAFQLSWKKDLDQLALAKYQSKSSKKTELYPNAKNGGYLKLPQSVR 810
Query: 660 SRFTFPAGNHLSLVPTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVTKFISSN 719
RF+ A S+VPTTE++++ KLL + + R+ LKMPA+ILDEKE+++++FISSN
Sbjct: 811 LRFSSSAPRRDSVVPTTELVSYMEKLLPGTHLKPFRDILKMPAMILDEKERVMSRFISSN 870
Query: 720 GLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCIEFYYKN 779
GL+EDP +EKER+MINPWTSEEKE+FL A GKDF+KIAS L KTTADCI++YYKN
Sbjct: 871 GLIEDPCDVEKERTMINPWTSEEKEIFLNLLAMHGKDFKKIASSLTQKTTADCIDYYYKN 930
Query: 780 HKSECFEKLKR-KDIGKLGKSYAAKTNLMASGKKWNHEVNVSSLDILSAASVM---ADVI 835
HKS+CF K+K+ + GK GK T ++A KKW E+ +SLDIL S++ A +
Sbjct: 931 HKSDCFGKIKKQRAYGKEGK----HTYMLAPRKKWKREMGAASLDILGDVSIIAANAGKV 986
Query: 836 AGNKRMRGRRYLL-GYGNVKASRGEDSIIER-SNSFDTLGDERETAAAADVLAGICGSFS 893
A + + ++ L G + + + + + E S SFD R+ A ADVLA G S
Sbjct: 987 ASTRPISSKKITLRGCSSANSLQHDGNNSEGCSYSFDF---PRKRTAGADVLA--VGPLS 1041
Query: 894 SEAMSSCITSSIDPVDGNKETKFLKANPLFKQP------------LTPDISQNADDETCS 941
E ++SC+ +S+ + LK N + K+P + + N +D++CS
Sbjct: 1042 PEQINSCLRTSVS--SRERCMDHLKFNHVVKKPRISHTLHNENSNTLHNENSNEEDDSCS 1099
Query: 942 DESCGEA--TEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFFSKTRKCLGLN 999
+ESCGE WTDDE +AF+Q S FGK+F ISR VGT++ + CK FFSK RKCLGL
Sbjct: 1100 EESCGETGPIHWTDDERSAFIQGFSLFGKNFASISRYVGTRSPDQCKVFFSKVRKCLGLE 1159
Query: 1000 LANPVPG-INGSPLNDDAN-GGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFH 1057
G ++ S D+ N GG SD +D C +E+ S + + K + P+ N
Sbjct: 1160 SIKFGSGNVSTSVSVDNGNEGGGSDLEDPCPMESNSGIVNNGVCAKMGMNSPTSPFNMNQ 1219
Query: 1058 DESNPLEATSLSAKLNESREISGTE-VCLEN 1087
D N + ++ A L+ S E +G + +CL++
Sbjct: 1220 DGVNQSGSANVKADLSRSEEENGQKYLCLKD 1250
Score = 80.9 bits (198), Expect = 3e-13
Identities = 43/101 (42%), Positives = 61/101 (59%), Gaps = 2/101 (1%)
Query: 2 FSEEPGHGYGVSRSGDKMLEEDGRPLVSRGDGKYGRSSRDNRGGPFGQRDWRGHSWEASN 61
F EE HGY SRS +M + + RP SRGD +Y R+ RD+R Q++W+ ++WE SN
Sbjct: 91 FVEETSHGYTSSRSSARMFD-NYRPSASRGDWRYTRNCRDDRVS-VSQKEWKCNTWEMSN 148
Query: 62 GSPNLSRRPQDMNNEQRSVDDSPTYSSHPHSDFVNTWEQHN 102
GS RP + N +RSVD+ P ++S HS VN+ + N
Sbjct: 149 GSSRSFERPFGIRNGRRSVDERPLHASDTHSTVVNSLDPAN 189
Score = 80.5 bits (197), Expect = 4e-13
Identities = 56/146 (38%), Positives = 81/146 (55%), Gaps = 24/146 (16%)
Query: 1329 CSSSAAEFPLLPQKVKQTDGHFKP-SFHSSNSEKTSRNGDVKLFGKILTNPSSTQNPNLT 1387
C+SSA + PL + GH + SF S++E+ +NGDVKLFG +LT
Sbjct: 1500 CTSSAPK-PLAVSHKEGRSGHSRSHSFSLSDTERLHKNGDVKLFGTVLT----------- 1547
Query: 1388 AKRSEENG---SHHPKLNNKSSNLNFTGHQNSDENLNFLKFGLENVPVMSYGYWEGNAIQ 1444
++ENG H+P +SS+ H +N + L+NVP+ SYG+W+GN I
Sbjct: 1548 ---TDENGIKQKHNPCGIVRSSSTLSRDHDTRHHYIN--QQHLQNVPITSYGFWDGNRI- 1601
Query: 1445 SRQSGLSSLPDSSFLLAKYPAAFSNY 1470
Q+GL+SLP+S+ LLA P AFS +
Sbjct: 1602 --QTGLTSLPESAKLLASCPEAFSTH 1625
>ref|XP_475559.1| unknown protein [Oryza sativa (japonica cultivar-group)]
gi|47900461|gb|AAT39237.1| unknown protein [Oryza sativa
(japonica cultivar-group)]
Length = 657
Score = 181 bits (458), Expect = 2e-43
Identities = 197/692 (28%), Positives = 289/692 (41%), Gaps = 109/692 (15%)
Query: 9 GYGVSRSGDKMLEEDGRPLVSRGDGKYG--------RSSRDNRGGPFGQRDWRGHSWEAS 60
GY SRS L++DG +G +YG R RD RG + + +RG+ + S
Sbjct: 39 GYTPSRSDRYWLDDDGGGGGYKGFSRYGGGGGGGSRRDGRDMRGS-YRRSPFRGYGSDFS 97
Query: 61 NGS-----PNLSRRPQDMNNEQRSVDDSPTYSSHPHSDFVNTWEQHNLKDQHAKTGGVNG 115
P L R P RSV +Y P D +
Sbjct: 98 RNHQEHPPPPLRRSPL------RSVAVPMSYD--PPGDRAD------------------- 130
Query: 116 LGTGPRCDRENSLSSIDWKPLKWTRSGSLSSRGSGFSHSSSSRSMAGTDSYEGKPNLKHK 175
R DR++ W+PL+ S S ++ +G ++ A S K
Sbjct: 131 -----RGDRDHHHRVTPWRPLRRRESRSDAADAAGAGPVPVGQAAAAAAS--------EK 177
Query: 176 NVTAVESNSGEATACVTSSMPSEDATSRKKPRLNWGEGLAKYEKKKVDVP---------- 225
+V+A S V + SE+ RKKPRL WG+GLAKYEK+KV P
Sbjct: 178 DVSARSS-------AVAAPQVSEEEAPRKKPRLGWGQGLAKYEKQKVQGPAESAEAVAEG 230
Query: 226 DPGSNKDGSVSSAGNMEPCSSI----SPNLVDKSPKVTGFSDCASP-ATPSSVACSSSPG 280
P + + ++ PC S SP + C SP A PS SP
Sbjct: 231 SPTATEQKGITHTPAPAPCVSPVAAPSPTPCASPVAAPSPAPCVSPVAAPSPAPPCKSPV 290
Query: 281 VDDKLLGKVGNADNDVSNLTDSPAPGFQNHLQKFYLNLDKLDVDSLNSLGSSIVELVQSD 340
+DK N + + + P P Q + LD+L+ D ++SL + ELVQ +
Sbjct: 291 PEDKSCELTANTVTESNK--NIPGPDVQACNNEVPTKLDQLEGDPIDSLAKVLSELVQHE 348
Query: 341 DPSSDDSGLVRSNAINKLLIWKADISKVLEMTESEIDLLENELKSLKSESVDRS--ECPV 398
D S DS R + ++KLL+ K ISK LE TE EID LE ELKS+ E+ +R+ + P
Sbjct: 349 DSCSGDSK--RLSNVSKLLLLKESISKELEKTELEIDSLEGELKSVNVEARNRTLKDPPT 406
Query: 399 ASGSQQADSSSKFYEERVEVSQKVIRPVPLKIISSDEPNTVKMPQSTNLCSIHENDKEED 458
A Q S S E+ I + E ++ Q+ N ++ EE
Sbjct: 407 AVTYAQNPSPSPVKEQGELTPSPKISMEQDADVKGSELMEIETAQAHNAKAV---SSEES 463
Query: 459 IDSPGSATSKFVEPLPVNAVSSSYTRGYDNLSRDMNAVQSTMMKCFVRCN--RKNTSVSA 516
+ PG A + P + + S G D++ Q C N + + S
Sbjct: 464 VACPGVALGQV--PAAADVIPSDPC-GKTGSGIDVDIEQREENPCQETFNAMKADGSSDL 520
Query: 517 CNNVNTPTEVKDSLGDVTFGANLCSSYGDTYKSIIASNKESANRAHKLFTKLVPKECKKH 576
+ EVK +L D IIA+N+ A + +L K VP +
Sbjct: 521 ATRPCSYREVKYNLMD----------------QIIAANRSEAKKNSQLLFKPVPADRSNL 564
Query: 577 GNMG---VSNDSFSHTSILQKFAEKKQFERFKERVIALKFKALHHLWKEDMRLLSIRKCR 633
+ +S+ + I +K A K +RFKE+++ KF+ L HLWKED+RLLS+RK R
Sbjct: 565 DLLASSYLSSQMKNDVIIKKKHAILKNRQRFKEQILTFKFRVLRHLWKEDVRLLSVRKQR 624
Query: 634 PKSHKKNELNVRTTCSSNMKNRSSIRSRFTFP 665
KSHK+ + + R++ S + + RSS RSR P
Sbjct: 625 SKSHKRTDQSNRSSQSGSQRQRSSNRSRLAVP 656
>gb|AAP97166.1| nuclear receptor co-repressor [Homo sapiens]
Length = 2343
Score = 103 bits (257), Expect = 5e-20
Identities = 72/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 130 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 189
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 190 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 249
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ ES + R +P ++ D +++ V
Sbjct: 250 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QESNEKQMRQLSVIPPMMFDAEQRRV- 306
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 307 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 366
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 367 LYYYLTKKNENYKALVRRNYGK 388
Score = 37.0 bits (84), Expect = 5.5
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 515 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 574
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDES-NP 1062
+ P + D + ES E + +++ N D + ++ +T S +P
Sbjct: 575 QKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSP 634
Query: 1063 LEATSLSAKLNESREISG-TEVCLE 1086
+EA S E+ G TE +E
Sbjct: 635 VEAVKPSEDSPENATSRGNTEPAVE 659
>gb|AAO32942.1| NCOR isoform b [Homo sapiens]
Length = 914
Score = 103 bits (257), Expect = 5e-20
Identities = 72/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 130 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 189
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 190 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 249
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ ES + R +P ++ D +++ V
Sbjct: 250 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QESNEKQMRQLSVIPPMMFDAEQRRV- 306
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 307 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 366
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 367 LYYYLTKKNENYKALVRRNYGK 388
Score = 37.0 bits (84), Expect = 5.5
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 515 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 574
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDES-NP 1062
+ P + D + ES E + +++ N D + ++ +T S +P
Sbjct: 575 QKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSP 634
Query: 1063 LEATSLSAKLNESREISG-TEVCLE 1086
+EA S E+ G TE +E
Sbjct: 635 VEAVKPSEDSPENATSRGNTEPAVE 659
>emb|CAI35323.1| nuclear receptor co-repressor 1 [Mus musculus]
gi|56207225|emb|CAI24057.1| nuclear receptor
co-repressor 1 [Mus musculus]
Length = 2454
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
Score = 38.1 bits (87), Expect = 2.5
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 6/131 (4%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 683
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDESNPL 1063
+ P + D + ES A V A D + S + + + A N+ ES P
Sbjct: 684 QKASRKPREERDVSQCES---VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPS 740
Query: 1064 EATSLSAKLNE 1074
+ +AK +E
Sbjct: 741 PSPVEAAKSSE 751
>sp|O75376|NCOR1_HUMAN Nuclear receptor corepressor 1 (N-CoR1) (N-CoR)
gi|22538461|ref|NP_006302.2| nuclear receptor
co-repressor 1 [Homo sapiens]
Length = 2440
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
Score = 36.6 bits (83), Expect = 7.2
Identities = 13/43 (30%), Positives = 26/43 (60%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF 989
E + WT++E + + G+++ I++ VGTK++ CK F+
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFY 666
>gb|AAH50594.1| NCOR1 protein [Homo sapiens]
Length = 550
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
>gb|AAH56862.1| NCOR1 protein [Homo sapiens]
Length = 518
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
>gb|AAH58511.1| NCOR1 protein [Homo sapiens]
Length = 534
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
>ref|XP_577103.1| PREDICTED: nuclear receptor co-repressor 1 [Rattus norvegicus]
Length = 2594
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
>emb|CAI35322.1| nuclear receptor co-repressor 1 [Mus musculus]
gi|56207226|emb|CAI24058.1| nuclear receptor
co-repressor 1 [Mus musculus]
Length = 2335
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
Score = 38.1 bits (87), Expect = 2.5
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 6/131 (4%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 683
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDESNPL 1063
+ P + D + ES A V A D + S + + + A N+ ES P
Sbjct: 684 QKASRKPREERDVSQCES---VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPS 740
Query: 1064 EATSLSAKLNE 1074
+ +AK +E
Sbjct: 741 PSPVEAAKSSE 751
>emb|CAI35321.1| nuclear receptor co-repressor 1 [Mus musculus]
gi|56207224|emb|CAI24056.1| nuclear receptor
co-repressor 1 [Mus musculus]
Length = 2341
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
Score = 38.1 bits (87), Expect = 2.5
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 6/131 (4%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 683
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDESNPL 1063
+ P + D + ES A V A D + S + + + A N+ ES P
Sbjct: 684 QKASRKPREERDVSQCES---VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPS 740
Query: 1064 EATSLSAKLNE 1074
+ +AK +E
Sbjct: 741 PSPVEAAKSSE 751
>emb|CAI35320.1| nuclear receptor co-repressor 1 [Mus musculus]
gi|56207223|emb|CAI24055.1| nuclear receptor
co-repressor 1 [Mus musculus]
Length = 910
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 130 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 189
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 190 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 249
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 250 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 306
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 307 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 366
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 367 LYYYLTKKNENYKALVRRNYGK 388
Score = 38.1 bits (87), Expect = 2.5
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 6/131 (4%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 514 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 573
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDESNPL 1063
+ P + D + ES A V A D + S + + + A N+ ES P
Sbjct: 574 QKASRKPREERDVSQCES---VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPS 630
Query: 1064 EATSLSAKLNE 1074
+ +AK +E
Sbjct: 631 PSPVEAAKSSE 641
>emb|CAI35318.1| nuclear receptor co-repressor 1 [Mus musculus]
gi|56207220|emb|CAI24052.1| nuclear receptor
co-repressor 1 [Mus musculus]
Length = 515
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
>dbj|BAA82999.2| KIAA1047 protein [Homo sapiens]
Length = 2348
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 250 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 309
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 310 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 369
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 370 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 426
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 427 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 486
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 487 LYYYLTKKNENYKALVRRNYGK 508
Score = 37.0 bits (84), Expect = 5.5
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 635 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 694
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDES-NP 1062
+ P + D + ES E + +++ N D + ++ +T S +P
Sbjct: 695 QKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSP 754
Query: 1063 LEATSLSAKLNESREISG-TEVCLE 1086
+EA S E+ G TE +E
Sbjct: 755 VEAVKPSEDSPENATSRGNTEPAVE 779
>sp|Q60974|NCOR1_MOUSE Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X
receptor interacting protein 13) (RIP13)
gi|1022718|gb|AAB17125.1| nuclear receptor co-repressor
gi|6754802|ref|NP_035438.1| nuclear receptor
co-repressor 1 [Mus musculus] gi|1583865|prf||2121436A
thyroid hormone receptor co-repressor
Length = 2453
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
Score = 38.1 bits (87), Expect = 2.5
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 6/131 (4%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 623 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 682
Query: 1005 PGINGSPLND-DANGGESDTDDACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDESNPL 1063
+ P + D + ES A V A D + S + + + A N+ ES P
Sbjct: 683 QKASRKPREERDVSQCES---VASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPS 739
Query: 1064 EATSLSAKLNE 1074
+ +AK +E
Sbjct: 740 PSPVEAAKSSE 750
>gb|AAH68996.1| NCOR1 protein [Homo sapiens]
Length = 522
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
>gb|AAC33550.1| nuclear receptor co-repressor N-CoR [Homo sapiens]
Length = 2440
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 239 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 298
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 299 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 358
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 359 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 415
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 416 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 475
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 476 LYYYLTKKNENYKALVRRNYGK 497
Score = 36.6 bits (83), Expect = 7.2
Identities = 13/43 (30%), Positives = 26/43 (60%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF 989
E + WT++E + + G+++ I++ VGTK++ CK F+
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFY 666
>gb|AAH86657.1| Ncor1 protein [Mus musculus]
Length = 2387
Score = 102 bits (254), Expect = 1e-19
Identities = 71/262 (27%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Query: 550 IIASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQ 600
I N++ A AHK+F L PK + + V +++ +++K F +
Sbjct: 240 IYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNH 299
Query: 601 FERFKERVIALKFKALHHLWKEDM-RLLSIRKCRPKSHKKNELNVRTTCSSNMKNRSSIR 659
+ +E+ I ++ L W++ + R+ + + + K K E + + R
Sbjct: 300 ARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQER 359
Query: 660 SRFTFPAGNHLSLV------PTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVT 713
+ G LS +EII+ S+ E+ + R +P ++ D +++ V
Sbjct: 360 FQRVGQRGAGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQRRV- 416
Query: 714 KFISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCI 773
KFI+ NGL+EDP+ + K+R +N WT EKE+F +KF K+F IAS+L+ K+ DC+
Sbjct: 417 KFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCV 476
Query: 774 EFYYKNHKSECFEKLKRKDIGK 795
+YY K+E ++ L R++ GK
Sbjct: 477 LYYYLTKKNENYKALVRRNYGK 498
Score = 37.0 bits (84), Expect = 5.5
Identities = 50/233 (21%), Positives = 82/233 (34%), Gaps = 25/233 (10%)
Query: 725 PLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCIEFYYKNHKSEC 784
P I E + WT EE E+ + G+++ IA + K+ A C FY+ +
Sbjct: 615 PEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHN 674
Query: 785 FEKLKRKDIGKLGKSYAAKTNLMASGKKWNHEVNVSSLD-ILSAASVMADV-IAGNKRMR 842
+ L ++ K+ ++ A +K E +VS + + S S D I +
Sbjct: 675 LDNLLQQHKQKVSRAVVA-------SRKPREERDVSQCESVASTVSAQEDEDIEASNEEE 727
Query: 843 GRRYLLGYGNVKASRGEDSIIERSNSFDTLGDERETAAAADVLAGICGSFSSEAMSSCIT 902
K + E + ++S ETA DV CG+ S +
Sbjct: 728 NPEDSEAVPTTKPAERESVEAQVTDSASA-----ETAEPMDVDHEECGAEGSSVLDPPAP 782
Query: 903 SSIDPVDGNKETKFLKANPLFKQPLTPDISQNADDETCSDESCGEATEWTDDE 955
+ D VD P + P D + ES E TE D++
Sbjct: 783 TKADSVD-----------PEMQVPENTASKGEGDAKERDLESTSEKTEARDED 824
Score = 37.0 bits (84), Expect = 5.5
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 947 EATEWTDDETAAFLQAVSSFGKDFEKISRCVGTKAQEHCKRFF--SKTRKCLGLNLANPV 1004
E + WT++E + + G+++ I++ VGTK++ CK F+ K R L L
Sbjct: 624 ETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHK 683
Query: 1005 PGINGSPLNDDANGGESDTDD----ACVVEAGSVVDADKSGNKTDEDLPSDALNTFHDES 1060
++ + + E D A V A D + S N+ + S+A+ T +
Sbjct: 684 QKVSRAVVASRKPREERDVSQCESVASTVSAQEDEDIEAS-NEEENPEDSEAVPT----T 738
Query: 1061 NPLEATSLSAKLNESREISGTE 1082
P E S+ A++ +S E
Sbjct: 739 KPAERESVEAQVTDSASAETAE 760
>gb|AAH94160.1| LOC443635 protein [Xenopus laevis]
Length = 507
Score = 102 bits (254), Expect = 1e-19
Identities = 67/260 (25%), Positives = 125/260 (47%), Gaps = 18/260 (6%)
Query: 551 IASNKESANRAHKLFTKLVPKE----CKKHGNMGVSNDSFSHTSILQK-----FAEKKQF 601
+ ++ A AHK+ L PK + + + +++ +++K F +
Sbjct: 190 LKKKQKKAEEAHKILEGLGPKVELPLYNQPSDTKIYHENIKTNQVMRKKLILFFKRRNHA 249
Query: 602 ERFKERVIALKFKALHHLWKEDMRLLS------IRKCRPKSHKKNELNVRTTCSSNMKNR 655
+ +E+ I ++ L W++ + + ++C+ + + + + +
Sbjct: 250 RKLREQNICQRYDQLMEAWEKKVDRIENNPRRKAKECKTREYYEKQFPEIRKQREQQERF 309
Query: 656 SSIRSRFTFPAGNHLSLVPTTEIINFTSKLLSESQAQLQRNTLKMPALILDEKEKMVTKF 715
+ R A S +EII+ S+ E+ + R +P ++ D ++K V KF
Sbjct: 310 QRVGQRGGLSATIARSEHEISEIIDGLSE--QENNEKQMRQLSVIPPMMFDAEQKRV-KF 366
Query: 716 ISSNGLVEDPLAIEKERSMINPWTSEEKELFLEKFAAFGKDFRKIASFLDHKTTADCIEF 775
I+ NGL+EDP+ + KER +N WT EKE+F EKF K+F IAS+L+ KT DC+ +
Sbjct: 367 INMNGLMEDPMKVYKERQFMNLWTDHEKEIFKEKFVQHPKNFGLIASYLERKTVCDCVLY 426
Query: 776 YYKNHKSECFEKLKRKDIGK 795
YY + K+E F+ L R++ K
Sbjct: 427 YYLSKKNENFKSLMRRNYPK 446
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.310 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,786,096,766
Number of Sequences: 2540612
Number of extensions: 122812799
Number of successful extensions: 309747
Number of sequences better than 10.0: 894
Number of HSP's better than 10.0 without gapping: 242
Number of HSP's successfully gapped in prelim test: 669
Number of HSP's that attempted gapping in prelim test: 304929
Number of HSP's gapped (non-prelim): 3884
length of query: 1620
length of database: 863,360,394
effective HSP length: 142
effective length of query: 1478
effective length of database: 502,593,490
effective search space: 742833178220
effective search space used: 742833178220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 82 (36.2 bits)
Medicago: description of AC126015.12