BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0288.8
(846 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_Q9SU29 Polyubiquitin-like protein [Arabidopsis thaliana] 767 0.0
UniRef100_UPI00003C1D0D UPI00003C1D0D UniRef100 entry 204 9e-51
UniRef100_UPI00002366BD UPI00002366BD UniRef100 entry 204 9e-51
UniRef100_UPI000021BFA3 UPI000021BFA3 UniRef100 entry 202 4e-50
UniRef100_Q9UTG2 E3 ubiquitin--protein ligase pub2 [Schizosaccha... 199 3e-49
UniRef100_UPI00002359AB UPI00002359AB UniRef100 entry 196 3e-48
UniRef100_UPI000036F5FC UPI000036F5FC UniRef100 entry 195 5e-48
UniRef100_Q7TMY8-3 Splice isoform 3 of Q7TMY8 [Mus musculus] 195 5e-48
UniRef100_Q7TMY8 E3 ubiquitin protein ligase URE-B1 [Mus musculus] 195 5e-48
UniRef100_Q7Z6Z7-2 Splice isoform 2 of Q7Z6Z7 [Homo sapiens] 195 5e-48
UniRef100_Q7Z6Z7 E3 ubiquitin protein ligase URE-B1 [Homo sapiens] 195 5e-48
UniRef100_UPI000042C1DD UPI000042C1DD UniRef100 entry 194 1e-47
UniRef100_UPI000023DAC1 UPI000023DAC1 UniRef100 entry 193 2e-47
UniRef100_Q6FN71 Similar to sp|P39940 Saccharomyces cerevisiae Y... 193 2e-47
UniRef100_Q9P4Z1 E3 ubiquitin protein ligase TOM1-like protein [... 193 2e-47
UniRef100_UPI0000219A9A UPI0000219A9A UniRef100 entry 192 3e-47
UniRef100_Q8BXY2 Mus musculus 7 days neonate cerebellum cDNA, RI... 192 4e-47
UniRef100_Q61YX3 Hypothetical protein CBG03363 [Caenorhabditis b... 192 4e-47
UniRef100_Q9P2M6 KIAA1320 protein [Homo sapiens] 192 4e-47
UniRef100_Q5VU99 HECT domain and ankyrin repeat containing, E3 u... 192 4e-47
>UniRef100_Q9SU29 Polyubiquitin-like protein [Arabidopsis thaliana]
Length = 873
Score = 767 bits (1981), Expect = 0.0
Identities = 428/870 (49%), Positives = 561/870 (64%), Gaps = 61/870 (7%)
Query: 14 KRKHDEIDDDEGGVSD-IDPIRMKKDDA----AKAVYSAVHHRS---------------- 52
KRK DE D GV++ ++ ++ ++ DA A A + + RS
Sbjct: 28 KRKRDEDSSDYVGVAESLEMLKKQEIDADHMAASAQQTLISWRSGENSRSLSSSGECSSS 87
Query: 53 -----IMLQFFVRMMGNGNTIVMQAHPDDTVQSIHERIQALKGIPVFEQRLIYNGKQLQS 107
LQ FVRMM G TIV+ A DTV+ +H+RI+ IP EQR+IY GKQLQ
Sbjct: 88 NRPESTRLQIFVRMMSGGKTIVIHAEKYDTVEKLHQRIEWKTKIPALEQRVIYKGKQLQR 147
Query: 108 EQTLAECSIGKDASLQLVGRMRSTGHPHAWQVINDMVSLVIRLCHNEPVHDANKTIKGLI 167
E +L SI +DASLQLV RM+ST HP AWQ I+D++ + R+ E + I I
Sbjct: 148 ENSLTYYSIEQDASLQLVARMQSTEHPVAWQTIDDIMYTISRMYKGE---NLQSNINEKI 204
Query: 168 TSYLNLSPKNDNDSASGYFQIFMSAT--AVLVSLYLSPYTGNKDCADSSIRHFLTTCKTT 225
++ + P ++S + Y IF +++ A LV LY S NK CA SS++ FL+ C
Sbjct: 205 VTFFAMIPVESDESIAKYLNIFSNSSVPAALVMLYASSLERNKSCAKSSVKLFLSNC--- 261
Query: 226 VSPPLHTQ--CARVVLDFCTLLKKRVSSEDPLYGFCRSTFGSLLETARVYCADSEGDNVK 283
V+ P + + C +VL+FC LL+K V + LY CR+T GS+LET DN
Sbjct: 262 VALPKNQKNYCLPIVLEFCKLLRK-VCPDQKLYVTCRNTLGSMLETF---------DNPH 311
Query: 284 GSILVQ------EIFPFVSELAKSLLVDLDLSIDSPSNAGTFLINVADFTAFLVPLRARI 337
G Q EIFPF +EL LL +L N+G + ++F LR I
Sbjct: 312 GVYNDQYETFGVEIFPFFTELTGLLLNEL------AQNSGPSFCDFQKVSSFWQQLRKVI 365
Query: 338 MEQQALRGSMPTQKRHKEALLVEEIEGLHLLYNDLLNKTDQCLQKLEQTWAGQGMMQGED 397
+ A +P + L EI LH L+ LL D C+ ++E + A + + E
Sbjct: 366 ELKVAF--PIPIVLPMQSTALEAEIRHLHRLFGSLLTTMDLCMCRVESSLADKEVGNSET 423
Query: 398 IYPAWSHYLSILKELYLISKLYDGAEEKLWKVLTRQRSVVCLLIVRYAKRTDEHQWILEH 457
+ +WS YLSILK + +S +Y GA+ +L +L + + L+V++AKR D+HQWI E+
Sbjct: 424 MSSSWSQYLSILKIINSMSNIYQGAKGQLAVMLNKNKVSFSALVVKFAKRGDDHQWIFEY 483
Query: 458 KCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFME 517
K TNFE+RRHLAM++FP+VKED+EE+HEMLIDRS LLSESFEYI A +LH GLFME
Sbjct: 484 KEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGGLFME 543
Query: 518 FKNEEATGPGVLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFS 577
FKNEEATGPGVLREWF LVCQ +FNP+N LF+ +D RRF PN ASKV PLH ++F F+
Sbjct: 544 FKNEEATGPGVLREWFYLVCQEIFNPKNTLFLRSADDFRRFSPNPASKVDPLHPDFFEFT 603
Query: 578 GRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDS 637
GRVIALALMHKVQVG++ DRVFFLQLAG I+LED+KD D +Y+SCKQILEMD +F DS
Sbjct: 604 GRVIALALMHKVQVGVLFDRVFFLQLAGLKISLEDIKDTDRIMYNSCKQILEMDPEFFDS 663
Query: 638 DA-LGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHF 696
+A LGLTFV E EELG +ELCP GK VNSKNR++Y+DLLI+ RF T I EQV F
Sbjct: 664 NAGLGLTFVLETEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQF 723
Query: 697 SKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITW 756
S+GFTD+LS S + FF+ L LEDLD ML G E+ IS++DWKAHTEYNG+KETD QI W
Sbjct: 724 SRGFTDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEYNGFKETDRQIDW 783
Query: 757 FWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGLASRLYIYKSPEPEDRLPSSHTCFYRM 816
FW+I+ +MT E+++ +LFFWTS K++PVEGF GL+S+LYIY+ E DRLP SHTCFYR+
Sbjct: 784 FWKILKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLYEANDRLPLSHTCFYRL 843
Query: 817 CFPAYSSMTVMQERLEVITQEHIGCSFGTW 846
C P Y ++T+M++RL +I Q+H+ SFG W
Sbjct: 844 CIPRYPTITLMEQRLRLIAQDHVSSSFGKW 873
>UniRef100_UPI00003C1D0D UPI00003C1D0D UniRef100 entry
Length = 571
Score = 204 bits (519), Expect = 9e-51
Identities = 125/385 (32%), Positives = 196/385 (50%), Gaps = 18/385 (4%)
Query: 460 VTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASL-HAGLFMEF 518
V +F+++++ + + D+ + + R+ + +SF Y +R + H L + F
Sbjct: 190 VLDFDNKKNYFTQQLHKGRRDHYTPLSLSVRRNSVFEDSFRYFSRKTGPEVKHGKLNVRF 249
Query: 519 KNEEATGPG-VLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFS 577
NEE G V REWF ++ +A+FNP ALF C DR + PN S V+P HL +F F
Sbjct: 250 TNEEGIDAGGVTREWFQVLARAMFNPDYALFQPCAADRTTYQPNRMSYVNPDHLSFFKFV 309
Query: 578 GRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDS 637
GR+I A+ + R F+ + GK + D++ DP + S + +L D +
Sbjct: 310 GRIIGKAIYDGRLLDAYFTRSFYKHILGKPVDYRDLESIDPEYFKSLEWMLSNDI----T 365
Query: 638 DALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFS 697
D L LTF + EE G+TKVV+L P G ++ V N+++Y+ L+ + R SI Q+ F
Sbjct: 366 DILDLTFSVDDEEFGETKVVDLKPNGTSISVTEANKQEYVRLVTEQRLTKSIKSQIDAFL 425
Query: 698 KGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWF 757
GF +I+ S + F Q LEL ++ G D I V+ WK +TE +GY D + W+
Sbjct: 426 GGFNEIIPSDLIRIFSEQELEL-----LISGLPD-IDVDAWKNNTELHGYSSGDAVVQWW 479
Query: 758 WEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRLYIYKSPEPEDRLPSSHTC 812
W V ++ LL F T +P+EGF L R I+K+ DRLP++HTC
Sbjct: 480 WRAVRSFDQTEKAKLLQFITGTSKVPLEGFAHLQGVQGTQRFNIHKA-YGADRLPAAHTC 538
Query: 813 FYRMCFPAYSSMTVMQERLEVITQE 837
F ++ P Y S ++ L + E
Sbjct: 539 FNQLDLPQYESYEKLRSSLLLAMNE 563
>UniRef100_UPI00002366BD UPI00002366BD UniRef100 entry
Length = 4022
Score = 204 bits (519), Expect = 9e-51
Identities = 120/355 (33%), Positives = 188/355 (52%), Gaps = 17/355 (4%)
Query: 486 EMLIDRSQLLSESFEYIARADTASL-HAGLFMEFKNEEATGPG-VLREWFLLVCQALFNP 543
++ + R Q+ +SF + L H L + F EE G V REWF ++ + +FNP
Sbjct: 3666 QLAVRRDQVFLDSFRALYFKSAEELKHGKLNVRFHGEEGVDAGGVTREWFQVLARGMFNP 3725
Query: 544 QNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQL 603
ALF+ DR F+PN S V+P HL +F F GR+I AL + R + +
Sbjct: 3726 DYALFIPVAADRTTFHPNRLSGVNPEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKCI 3785
Query: 604 AGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGG 663
G++++++D++ D Y S +LE D +D + TF E ++ G+ + ++L G
Sbjct: 3786 LGRNVSIKDMETLDLDYYKSLLWMLENDI----TDIITETFAVETDDFGEKQTIDLIENG 3841
Query: 664 KNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLD 723
+N+ V +N+E+Y+ ++ R V S+ EQ+ +F KGF +I+ F Q LEL
Sbjct: 3842 RNIPVTQENKEEYVQKVVDYRLVASVREQLDNFLKGFHEIIPPELISIFNEQELEL---- 3897
Query: 724 WMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLP 783
++ G + I V+DWKA+TEY+ Y + QI WFW V E+R LL F T +P
Sbjct: 3898 -LISGLPE-IDVDDWKANTEYHNYSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3955
Query: 784 VEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
+ GF L SR I++ +DRLPSSHTCF ++ P Y S +++RL +
Sbjct: 3956 LNGFKELEGMNGVSRFNIHRDYGNKDRLPSSHTCFNQLDLPEYDSYETLRQRLYI 4010
>UniRef100_UPI000021BFA3 UPI000021BFA3 UniRef100 entry
Length = 4048
Score = 202 bits (513), Expect = 4e-50
Identities = 118/353 (33%), Positives = 188/353 (52%), Gaps = 17/353 (4%)
Query: 486 EMLIDRSQLLSESFEYIARADTASLHAG-LFMEFKNEEATGPG-VLREWFLLVCQALFNP 543
++ + R + +SF+ + + G L + F EE G V REWF ++ + +F+P
Sbjct: 3692 QLSVRRDHVFHDSFKSLYFKKGEEMKYGKLNIRFHGEEGVDAGGVTREWFQVLSRQMFDP 3751
Query: 544 QNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQL 603
LF +DR F+PN S ++ HL +F F GR+I AL + R + ++
Sbjct: 3752 NYVLFTPVSSDRTTFHPNKLSSINDEHLMFFKFIGRIIGKALYEGRVLDCYFSRAVYKRI 3811
Query: 604 AGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGG 663
GK ++++D++ DP Y S +LE D +D + TF E + G TK V+LC G
Sbjct: 3812 LGKPVSVKDMESFDPEYYKSLVWMLENDI----TDIITETFAVEDDAFGVTKTVDLCENG 3867
Query: 664 KNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLD 723
+N+ V N+ +Y+ L+++ + + S+ +Q++ F +GF DI+ + F Q LEL
Sbjct: 3868 RNIPVTEDNKHEYVRLVVEHKLLASVKDQMAEFLQGFHDIIPAELIAIFNEQELEL---- 3923
Query: 724 WMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLP 783
++ G D I V+DWKAHTEY+ Y+ + QI WFW V E+R LL F T +P
Sbjct: 3924 -LISGLPD-IDVDDWKAHTEYHNYQPSSQQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3981
Query: 784 VEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERL 831
+ GF L SR I++ DRLPSSHTCF ++ P Y S V+++++
Sbjct: 3982 LNGFKELEGMNGVSRFNIHRDYGRPDRLPSSHTCFNQLDLPEYESYDVLRKQI 4034
>UniRef100_Q9UTG2 E3 ubiquitin--protein ligase pub2 [Schizosaccharomyces pombe]
Length = 671
Score = 199 bits (506), Expect = 3e-49
Identities = 124/390 (31%), Positives = 202/390 (51%), Gaps = 19/390 (4%)
Query: 462 NFESRRHLAMMMF-PEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFMEFKN 520
N E +R +A M PE+ + +L ++ + R+ ++++ I++ + + L + F+N
Sbjct: 294 NDEYQRKIAYMYDRPEMAVNDAQL-QLKVSRATTFEDAYDIISKLSVSDMKKKLLIRFRN 352
Query: 521 EEATG-PGVLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGR 579
E+ GV RE+F ++ A+FNP +LF +D + S V+P YF F GR
Sbjct: 353 EDGLDYGGVSREFFYILSHAIFNPGYSLFEYATDDNYGLQISPLSSVNPDFRSYFRFVGR 412
Query: 580 VIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDA 639
V+ LA+ H+ + + F+ ++ K + LEDVKD D Y S K I D D ++
Sbjct: 413 VMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWIKNNDVD----ES 468
Query: 640 LGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKG 699
L L F E G++ V+L P G+N+ VN++N+ Y+ L + + VTS EQ + G
Sbjct: 469 LCLNFSVEENRFGESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGG 528
Query: 700 FTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWE 759
+++ S Q F +LD +L+G D I V+DWK T+Y Y ETD + WFWE
Sbjct: 529 LNELIPDSVLQIF-----NENELDTLLNGKRD-IDVQDWKRFTDYRSYTETDDIVIWFWE 582
Query: 760 IVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL----ASRLYIYKSPEPEDRLPSSHTCFYR 815
++ + E++ LL F T LP+ GF + R + + +LP +HTCF R
Sbjct: 583 LLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKVGHISQLPKAHTCFNR 642
Query: 816 MCFPAYSSMTVMQERLEVITQEHIGCSFGT 845
+ P Y+S ++++L + QE G FGT
Sbjct: 643 LDIPPYNSKEELEQKLTIAIQETAG--FGT 670
>UniRef100_UPI00002359AB UPI00002359AB UniRef100 entry
Length = 821
Score = 196 bits (497), Expect = 3e-48
Identities = 120/358 (33%), Positives = 187/358 (51%), Gaps = 17/358 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPGVL-REWFLLVCQALFNPQNAL 547
+ R+ + +S+ I R + L L ++F E+ G L RE+F L+ +FNP L
Sbjct: 471 VRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCL 530
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F +D N S V+P HL YF F GRV+ LA+ H+ + F+ + K
Sbjct: 531 FEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKK 590
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
++L+D++ D L+ + LE D + I + LTF + E+ G+ + +EL PGG+++
Sbjct: 591 VSLQDMEGVDEDLHRNLTWTLENDIEGI----IDLTFTVDDEKFGERRTIELKPGGEDIP 646
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V ++N+ +Y++L+ + + V + EQ + F GF +++ + F + LEL L
Sbjct: 647 VTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELEL------LI 700
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
G I V+DWK HT+Y GY+E D I FW+IV AEQ+ LL F T +PV GF
Sbjct: 701 GGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQKSRLLQFTTGTSRIPVNGF 760
Query: 788 CGLAS-----RLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIG 840
L R I KS +P LP SHTCF R+ P Y S V++ +L + +E +G
Sbjct: 761 KDLQGSDGPRRFTIEKSGDP-IALPKSHTCFNRLDLPPYKSHEVLEHKLSIAVEETLG 817
>UniRef100_UPI000036F5FC UPI000036F5FC UniRef100 entry
Length = 549
Score = 195 bits (495), Expect = 5e-48
Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R + +S+ + R + L++ F+ EE G +LREW++++ + +FNP AL
Sbjct: 196 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 255
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F P DR + N +S +P HL YF F GR++A A+ + R F+ + GK
Sbjct: 256 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 315
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ D++ D Y +LE D + D LTF EV+E G +V +L P G N++
Sbjct: 316 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 372
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V +N+++Y+ L+ + R +I +Q++ F +GF +I+ F Q LEL L
Sbjct: 373 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 426
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
TI ++D K++TEY+ Y+ IQI WFW + R L F T +P++GF
Sbjct: 427 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 486
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
L + I++ DRLPS+HTCF ++ PAY S ++ L + QE CS
Sbjct: 487 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 543
Query: 843 FG 844
G
Sbjct: 544 EG 545
>UniRef100_Q7TMY8-3 Splice isoform 3 of Q7TMY8 [Mus musculus]
Length = 2734
Score = 195 bits (495), Expect = 5e-48
Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R + +S+ + R + L++ F+ EE G +LREW++++ + +FNP AL
Sbjct: 2381 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 2440
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F P DR + N +S +P HL YF F GR++A A+ + R F+ + GK
Sbjct: 2441 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 2500
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ D++ D Y +LE D + D LTF EV+E G +V +L P G N++
Sbjct: 2501 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 2557
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V +N+++Y+ L+ + R +I +Q++ F +GF +I+ F Q LEL L
Sbjct: 2558 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 2611
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
TI ++D K++TEY+ Y+ IQI WFW + R L F T +P++GF
Sbjct: 2612 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 2671
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
L + I++ DRLPS+HTCF ++ PAY S ++ L + QE CS
Sbjct: 2672 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 2728
Query: 843 FG 844
G
Sbjct: 2729 EG 2730
>UniRef100_Q7TMY8 E3 ubiquitin protein ligase URE-B1 [Mus musculus]
Length = 2749
Score = 195 bits (495), Expect = 5e-48
Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R + +S+ + R + L++ F+ EE G +LREW++++ + +FNP AL
Sbjct: 2396 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 2455
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F P DR + N +S +P HL YF F GR++A A+ + R F+ + GK
Sbjct: 2456 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 2515
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ D++ D Y +LE D + D LTF EV+E G +V +L P G N++
Sbjct: 2516 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 2572
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V +N+++Y+ L+ + R +I +Q++ F +GF +I+ F Q LEL L
Sbjct: 2573 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 2626
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
TI ++D K++TEY+ Y+ IQI WFW + R L F T +P++GF
Sbjct: 2627 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 2686
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
L + I++ DRLPS+HTCF ++ PAY S ++ L + QE CS
Sbjct: 2687 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 2743
Query: 843 FG 844
G
Sbjct: 2744 EG 2745
>UniRef100_Q7Z6Z7-2 Splice isoform 2 of Q7Z6Z7 [Homo sapiens]
Length = 3344
Score = 195 bits (495), Expect = 5e-48
Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R + +S+ + R + L++ F+ EE G +LREW++++ + +FNP AL
Sbjct: 2991 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 3050
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F P DR + N +S +P HL YF F GR++A A+ + R F+ + GK
Sbjct: 3051 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 3110
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ D++ D Y +LE D + D LTF EV+E G +V +L P G N++
Sbjct: 3111 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 3167
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V +N+++Y+ L+ + R +I +Q++ F +GF +I+ F Q LEL L
Sbjct: 3168 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 3221
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
TI ++D K++TEY+ Y+ IQI WFW + R L F T +P++GF
Sbjct: 3222 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 3281
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
L + I++ DRLPS+HTCF ++ PAY S ++ L + QE CS
Sbjct: 3282 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 3338
Query: 843 FG 844
G
Sbjct: 3339 EG 3340
>UniRef100_Q7Z6Z7 E3 ubiquitin protein ligase URE-B1 [Homo sapiens]
Length = 3360
Score = 195 bits (495), Expect = 5e-48
Identities = 115/362 (31%), Positives = 183/362 (49%), Gaps = 18/362 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R + +S+ + R + L++ F+ EE G +LREW++++ + +FNP AL
Sbjct: 3007 VRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYAL 3066
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F P DR + N +S +P HL YF F GR++A A+ + R F+ + GK
Sbjct: 3067 FRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKS 3126
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ D++ D Y +LE D + D LTF EV+E G +V +L P G N++
Sbjct: 3127 VRYTDMESEDYHFYQGLVYLLENDVSTLGYD---LTFSTEVQEFGVCEVRDLKPNGANIL 3183
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V +N+++Y+ L+ + R +I +Q++ F +GF +I+ F Q LEL L
Sbjct: 3184 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELEL------LI 3237
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
TI ++D K++TEY+ Y+ IQI WFW + R L F T +P++GF
Sbjct: 3238 SGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGF 3297
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIGCS 842
L + I++ DRLPS+HTCF ++ PAY S ++ L + QE CS
Sbjct: 3298 AALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQE---CS 3354
Query: 843 FG 844
G
Sbjct: 3355 EG 3356
>UniRef100_UPI000042C1DD UPI000042C1DD UniRef100 entry
Length = 833
Score = 194 bits (492), Expect = 1e-47
Identities = 117/371 (31%), Positives = 181/371 (48%), Gaps = 16/371 (4%)
Query: 475 PEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPGVL-REWF 533
P ++ + + H M + R + S+ I R L L ++F+ E+ G L RE+F
Sbjct: 470 PALRSNTGQCH-MKVSRDNIFEGSYTEIMRQTPNDLKKRLMIKFEGEDGLDYGGLSREFF 528
Query: 534 LLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGI 593
L+ +FNP LF +D N S V+P HL YF F GRV+ L + H+ +
Sbjct: 529 FLLSHEMFNPFYCLFEYSAHDNYTLQINPNSGVNPEHLNYFKFIGRVVGLGIFHRRFLDA 588
Query: 594 VLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGD 653
F+ + GK I L+D++ D L+ +LE D + D +T E G+
Sbjct: 589 YFIVSFYKMILGKKIALQDLESVDAGLFRGLTWMLENDITGVIEDTFSIT----EEHFGE 644
Query: 654 TKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFF 713
V+L PGG+++ V N++ Y+DL+ + R +SEQ F GF +++ F
Sbjct: 645 VVTVDLKPGGRDVEVTEDNKKDYVDLVTEYRISKRVSEQFQAFMSGFNELIPQELINVFD 704
Query: 714 FQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLL 773
+ LEL L G I V+DW+ HT+Y GY +D + WFW+IV AE++ LL
Sbjct: 705 ERELEL------LIGGMSEIDVDDWQKHTDYRGYNPSDEVVEWFWKIVKNWPAEKKSRLL 758
Query: 774 FFWTSVKYLPVEGFCGL----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQE 829
F T +PV GF L R + + +LP SHTCF R+ PAY S +++
Sbjct: 759 QFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVTQLPKSHTCFNRIDLPAYKSYEALEQ 818
Query: 830 RLEVITQEHIG 840
+L + +E +G
Sbjct: 819 KLTIAVEETVG 829
>UniRef100_UPI000023DAC1 UPI000023DAC1 UniRef100 entry
Length = 3991
Score = 193 bits (490), Expect = 2e-47
Identities = 117/377 (31%), Positives = 198/377 (52%), Gaps = 18/377 (4%)
Query: 454 ILEHKCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFEYIARADTASLHAG 513
+LE N+ +R + + + +Y L ++ + R + +SF+++ + G
Sbjct: 3604 VLEFDNKRNYFNRSVHSRSGNSQSRSNYAAL-QLSVRREHVFHDSFKHLYFKSGDEMKFG 3662
Query: 514 -LFMEFKNEEATGPG-VLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHL 571
L + F EE G V REWF ++ + +F+P LF +DR F+PN S ++ HL
Sbjct: 3663 KLNIRFHGEEGVDAGGVTREWFQVLSRQMFDPNYVLFTPVSSDRTTFHPNKLSGINDEHL 3722
Query: 572 EYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMD 631
+F F GR+I AL + R + ++ GK ++++D++ DP Y S +L+ D
Sbjct: 3723 LFFKFIGRIIGKALYEGRVLDCYFSRALYKRILGKSVSVKDMESFDPDYYKSLCWMLDND 3782
Query: 632 SDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISE 691
+D + TF E +E G T VV+L P G+ + V +N+ Y+ L+++ + ++S+ E
Sbjct: 3783 I----TDIITETFSVEDDEFGVTNVVDLIPNGREIAVTEENKHDYVRLVVEHKLLSSVKE 3838
Query: 692 QVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETD 751
Q++HF +GF DI+ + F Q LEL ++ G D I ++DWK++TEY+ Y +
Sbjct: 3839 QMAHFLQGFHDIIPAELISIFNEQELEL-----LISGLPD-IDIDDWKSNTEYHNYTPSS 3892
Query: 752 IQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRLYIYKSPEPEDRL 806
QI WFW + E+R +L F T +P+ GF L +R I++ ++RL
Sbjct: 3893 QQIQWFWRALRSFDKEERAKMLQFVTGTSKVPLNGFKELEGMNGVNRFNIHRDYGNKNRL 3952
Query: 807 PSSHTCFYRMCFPAYSS 823
PSSHTCF ++ P Y S
Sbjct: 3953 PSSHTCFNQLDLPEYES 3969
>UniRef100_Q6FN71 Similar to sp|P39940 Saccharomyces cerevisiae YER125w Ubiquitin--
protein ligase [Candida glabrata]
Length = 822
Score = 193 bits (490), Expect = 2e-47
Identities = 120/358 (33%), Positives = 180/358 (49%), Gaps = 17/358 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATG-PGVLREWFLLVCQALFNPQNAL 547
+ R+ + ++++ I R L L ++F EE GV RE+F L+ +FNP L
Sbjct: 472 VRRNNIFEDAYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCL 531
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F +D N S ++P HL YF F GRV+ L + H+ + + + K
Sbjct: 532 FEYSAHDNYTIQINSNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKK 591
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ L+D++ D +Y+S K +LE D + L LTF + E G+ V+L P G+N+
Sbjct: 592 VALQDMEGVDADVYNSLKWMLENSIDGV----LDLTFSADDERFGEVVTVDLKPDGRNIE 647
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V + +++Y++L + R V +SEQ F GF +++ F + LEL L
Sbjct: 648 VTDEVKKEYVELYSQWRIVDRVSEQFKAFMDGFNELIPEDLVTVFDERELEL------LI 701
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
G I +EDWK HT+Y GY+E+D I WFW+ V EQR LL F T +PV GF
Sbjct: 702 GGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGF 761
Query: 788 CGLAS-----RLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIG 840
L R I K+ E E +LP SHTCF R+ P Y+ M ++L + +E IG
Sbjct: 762 KDLQGSDGPRRFTIEKAGEVE-QLPKSHTCFNRVDLPPYADYDSMAKKLTLAVEETIG 818
>UniRef100_Q9P4Z1 E3 ubiquitin protein ligase TOM1-like protein [Neurospora crassa]
Length = 4065
Score = 193 bits (490), Expect = 2e-47
Identities = 128/436 (29%), Positives = 218/436 (49%), Gaps = 26/436 (5%)
Query: 410 KELYLISKLYDGAEEKLWKVLTRQRSVVCLLIVRYAKR--TDEHQWILEHKCVTNFESRR 467
KE+ L S + L+ T + + +VR+ + + ++++ V F+++R
Sbjct: 3628 KEMLLTSPPPEDRIAGLFFTFTEEHRRILNELVRHNPKLMSGTFSLLVKNPKVLEFDNKR 3687
Query: 468 HL----AMMMFPEVKEDYEELHEMLIDRSQLLSESFE--YIARADTASLHAGLFMEFKNE 521
+ + + + + L ++ + R + +SF Y +AD L + F+ E
Sbjct: 3688 NYFNRSVHSKYQQTRHSFPPL-QLQVRREHVFHDSFRSLYYKKADELKF-GKLNIRFQGE 3745
Query: 522 EATGPG-VLREWFLLVCQALFNPQNALFVACPNDRRRFYPNHASKVHPLHLEYFGFSGRV 580
E G V REWF ++ + +F+P LFV +DR F+PN S ++ HL +F F GR+
Sbjct: 3746 EGVDAGGVTREWFQVLSRQMFDPNYVLFVPVSSDRTTFHPNKLSPINDEHLPFFKFIGRI 3805
Query: 581 IALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFLYSSCKQILEMDSDFIDSDAL 640
I AL + R + ++ GK ++++D++ DP Y S +LE D +D +
Sbjct: 3806 IGKALYEGRLLECYFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLENDI----TDII 3861
Query: 641 GLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLLIKDRFVTSISEQVSHFSKGF 700
TF E + G+ KVV+L G+N+ V +N+ +Y+ L+++ + +TS+ +Q+ F GF
Sbjct: 3862 TETFSVEDDVFGEVKVVDLIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGF 3921
Query: 701 TDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKAHTEYNGYKETDIQITWFWEI 760
+I+ F Q LEL ++ G D I ++DWKA+TEY+ Y QI WFW
Sbjct: 3922 HEIIPEELIAIFNEQELEL-----LISGLPD-IDIDDWKANTEYHNYSAGAPQIQWFWRA 3975
Query: 761 VGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRLYIYKSPEPEDRLPSSHTCFYR 815
V E+ LL F T +P+ GF L SR I++ +DRLPSSHTCF +
Sbjct: 3976 VRSFDKEELAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQ 4035
Query: 816 MCFPAYSSMTVMQERL 831
+ P Y + ++ +L
Sbjct: 4036 LDLPEYENYETLRSQL 4051
>UniRef100_UPI0000219A9A UPI0000219A9A UniRef100 entry
Length = 791
Score = 192 bits (489), Expect = 3e-47
Identities = 116/357 (32%), Positives = 178/357 (49%), Gaps = 14/357 (3%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPGVL-REWFLLVCQALFNPQNAL 547
+ RS + +SF I+R L L ++F E+ G L RE+F L+ +FNP L
Sbjct: 440 VRRSHIFEDSFAEISRQSATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCL 499
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F +D N S ++P HL YF F GRV+ LA+ H+ + + + GK
Sbjct: 500 FEYSAHDNYTLQINPHSGINPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYKMVLGKS 559
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ L D++ D + S + +L+ D I L TF E E G V +L P G+N+
Sbjct: 560 VALPDMEGVDADFHRSLQWMLDND---ISGGILEQTFSTEDERFGVITVEDLIPNGRNID 616
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
V ++N+++Y+DL++K R I+EQ F GF +++ F + LEL L
Sbjct: 617 VTNENKKEYVDLMVKWRIEKRIAEQFEAFKTGFHELIPQDLINVFDERELEL------LI 670
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
G I V+DWK HT+Y GY E D I +FW+ V EQ+ LL F T +PV GF
Sbjct: 671 GGIAEIDVDDWKKHTDYRGYTEQDEVIQFFWQTVRSWDGEQKSRLLQFTTGTSRIPVNGF 730
Query: 788 CGL----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQEHIG 840
L R + + + LP +HTCF R+ P Y S+ ++Q+++ + +E +G
Sbjct: 731 KDLQGSDGPRRFTIEKAGEINNLPKAHTCFNRLDLPPYKSLEMLQQKMTIAVEETMG 787
>UniRef100_Q8BXY2 Mus musculus 7 days neonate cerebellum cDNA, RIKEN full-length
enriched library, clone:A730034A22 product:hypothetical
Ankyrin- repeat/HECT domain (Ubiquitin-protein ligase)
containing protein, full insert sequence [Mus musculus]
Length = 909
Score = 192 bits (488), Expect = 4e-47
Identities = 129/399 (32%), Positives = 191/399 (47%), Gaps = 25/399 (6%)
Query: 441 IVRYAKRTDEHQWILEHKCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFE 500
I++ D +W EH H V E +L+ R + S E
Sbjct: 518 IIKAQPFKDRCEWFYEHL---------HSGQPDSDMVHRPVSENDILLVHRDSIFRSSCE 568
Query: 501 YIARADTASLHAGLFMEFKNEEATGPGVLREWFLLVCQALFNPQNALFVACPNDRRRFYP 560
+++A+ A L G+ + F EE G GV+REWF ++ + NP ALF D F P
Sbjct: 569 IVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSA-DGTTFQP 627
Query: 561 NHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFL 620
N S V+P HL YF F+G+++ LAL H+ V I R F+ + G + +DV DP
Sbjct: 628 NSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEY 687
Query: 621 YSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLL 680
+ + IL+ D I L LTF E + G + V L PGG +++V N+ +Y+ L+
Sbjct: 688 AKNLQWILDND---ISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLV 744
Query: 681 IKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKA 740
+ R +I Q++ F +GF + S Q F LEL +L G + I V DW
Sbjct: 745 TELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELEL-----LLSGMPE-IDVNDWIK 798
Query: 741 HTEY-NGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRL 794
+TEY +GY+ D I WFWE+V +T E+R +LL F T +P GF +
Sbjct: 799 NTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNF 858
Query: 795 YIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
I P + LP+S TC + P Y S ++++RL V
Sbjct: 859 TIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLV 897
>UniRef100_Q61YX3 Hypothetical protein CBG03363 [Caenorhabditis briggsae]
Length = 4140
Score = 192 bits (488), Expect = 4e-47
Identities = 109/355 (30%), Positives = 181/355 (50%), Gaps = 15/355 (4%)
Query: 489 IDRSQLLSESFEYIARADTASLHAGLFMEFKNEEATGPG-VLREWFLLVCQALFNPQNAL 547
+ R+++ S+SF + R + ++ F+ EE G +LREWF ++ + +FNP AL
Sbjct: 3787 VSRNRVFSDSFRELFRLRPSDWKNRFYIIFQGEEGQDAGGLLREWFSVITREIFNPNYAL 3846
Query: 548 FVACPNDRRRFYPNHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKH 607
F+ P D + N AS ++P HL+YF F GR+IA ++ + R F+ +
Sbjct: 3847 FITAPGDMVTYMINKASYINPEHLDYFKFVGRLIAKSVFEHKYLDCYFTRAFYKHILNLP 3906
Query: 608 ITLEDVKDADPFLYSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLI 667
+ +D++ DP + S +L+ D +D D LTF EVEE G V +L P G+ +
Sbjct: 3907 VRYQDLESEDPAFFKSLDFLLQNSIDDLDLD---LTFSTEVEEFGVRSVRDLKPNGRKIE 3963
Query: 668 VNSKNREKYIDLLIKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLH 727
VN N+++Y+ L+ + + SI +Q+ F GF +I+ F Q LEL L
Sbjct: 3964 VNDANKDEYVKLVCQMKMTGSIRKQLDAFLTGFYEIIPKDLISMFNEQELEL------LI 4017
Query: 728 GSEDTISVEDWKAHTEYNGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGF 787
T+ ++D A+T+Y G+++T I WFW + E + L F T +P++GF
Sbjct: 4018 SGLPTVDIDDMAANTDYKGFQKTSTHIQWFWRALRSFEKEDKAKFLQFVTGTSKVPLQGF 4077
Query: 788 CGL-----ASRLYIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEVITQE 837
L +L I+ DRLP++HTCF ++ P Y S +++ L + +E
Sbjct: 4078 ASLEGMNGVQKLSIHLDSRGGDRLPAAHTCFNQLDLPQYDSYEKLRQSLLLAIRE 4132
>UniRef100_Q9P2M6 KIAA1320 protein [Homo sapiens]
Length = 567
Score = 192 bits (488), Expect = 4e-47
Identities = 129/399 (32%), Positives = 191/399 (47%), Gaps = 25/399 (6%)
Query: 441 IVRYAKRTDEHQWILEHKCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFE 500
I++ D +W EH H V E +L+ R + S E
Sbjct: 176 IIKAQPFKDRCEWFYEHL---------HSGQPDSDMVHRPVNENDILLVHRDSIFRSSCE 226
Query: 501 YIARADTASLHAGLFMEFKNEEATGPGVLREWFLLVCQALFNPQNALFVACPNDRRRFYP 560
+++A+ A L G+ + F EE G GV+REWF ++ + NP ALF D F P
Sbjct: 227 VVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSA-DGTTFQP 285
Query: 561 NHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFL 620
N S V+P HL YF F+G+++ LAL H+ V I R F+ + G + +DV DP
Sbjct: 286 NSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEY 345
Query: 621 YSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLL 680
+ + IL+ D I L LTF E + G + V L PGG +++V N+ +Y+ L+
Sbjct: 346 AKNLQWILDND---ISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLV 402
Query: 681 IKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKA 740
+ R +I Q++ F +GF + S Q F LEL +L G + I V DW
Sbjct: 403 TELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELEL-----LLSGMPE-IDVSDWIK 456
Query: 741 HTEY-NGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRL 794
+TEY +GY+ D I WFWE+V +T E+R +LL F T +P GF +
Sbjct: 457 NTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNF 516
Query: 795 YIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
I P + LP+S TC + P Y S ++++RL V
Sbjct: 517 TIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLV 555
>UniRef100_Q5VU99 HECT domain and ankyrin repeat containing, E3 ubiquitin protein
ligase 1 [Homo sapiens]
Length = 903
Score = 192 bits (488), Expect = 4e-47
Identities = 129/399 (32%), Positives = 191/399 (47%), Gaps = 25/399 (6%)
Query: 441 IVRYAKRTDEHQWILEHKCVTNFESRRHLAMMMFPEVKEDYEELHEMLIDRSQLLSESFE 500
I++ D +W EH H V E +L+ R + S E
Sbjct: 512 IIKAQPFKDRCEWFYEHL---------HSGQPDSDMVHRPVNENDILLVHRDSIFRSSCE 562
Query: 501 YIARADTASLHAGLFMEFKNEEATGPGVLREWFLLVCQALFNPQNALFVACPNDRRRFYP 560
+++A+ A L G+ + F EE G GV+REWF ++ + NP ALF D F P
Sbjct: 563 VVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSA-DGTTFQP 621
Query: 561 NHASKVHPLHLEYFGFSGRVIALALMHKVQVGIVLDRVFFLQLAGKHITLEDVKDADPFL 620
N S V+P HL YF F+G+++ LAL H+ V I R F+ + G + +DV DP
Sbjct: 622 NSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEY 681
Query: 621 YSSCKQILEMDSDFIDSDALGLTFVREVEELGDTKVVELCPGGKNLIVNSKNREKYIDLL 680
+ + IL+ D I L LTF E + G + V L PGG +++V N+ +Y+ L+
Sbjct: 682 AKNLQWILDND---ISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLV 738
Query: 681 IKDRFVTSISEQVSHFSKGFTDILSSSKFQQFFFQSLELEDLDWMLHGSEDTISVEDWKA 740
+ R +I Q++ F +GF + S Q F LEL +L G + I V DW
Sbjct: 739 TELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELEL-----LLSGMPE-IDVSDWIK 792
Query: 741 HTEY-NGYKETDIQITWFWEIVGRMTAEQRKVLLFFWTSVKYLPVEGFCGL-----ASRL 794
+TEY +GY+ D I WFWE+V +T E+R +LL F T +P GF +
Sbjct: 793 NTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNF 852
Query: 795 YIYKSPEPEDRLPSSHTCFYRMCFPAYSSMTVMQERLEV 833
I P + LP+S TC + P Y S ++++RL V
Sbjct: 853 TIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLV 891
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.322 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,398,416,826
Number of Sequences: 2790947
Number of extensions: 58362299
Number of successful extensions: 139587
Number of sequences better than 10.0: 1425
Number of HSP's better than 10.0 without gapping: 1219
Number of HSP's successfully gapped in prelim test: 206
Number of HSP's that attempted gapping in prelim test: 135248
Number of HSP's gapped (non-prelim): 2431
length of query: 846
length of database: 848,049,833
effective HSP length: 136
effective length of query: 710
effective length of database: 468,481,041
effective search space: 332621539110
effective search space used: 332621539110
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 79 (35.0 bits)
Lotus: description of TM0288.8