BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0192.11
         (571 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_UPI00001CFC7D UPI00001CFC7D UniRef100 entry                  51  8e-05
UniRef100_UPI000023F6CB UPI000023F6CB UniRef100 entry                  49  3e-04
UniRef100_Q6DIC2 Early endosome antigen 1 [Mus musculus]               49  3e-04
UniRef100_UPI0000361937 UPI0000361937 UniRef100 entry                  49  5e-04
UniRef100_P16947 M protein, serotype 49 precursor [Streptococcus...    47  0.002
UniRef100_UPI0000369CDB UPI0000369CDB UniRef100 entry                  46  0.003
UniRef100_UPI0000369CDA UPI0000369CDA UniRef100 entry                  46  0.003
UniRef100_Q658F8 Hypothetical protein P0015E04.9 [Oryza sativa]        46  0.003
UniRef100_Q86UP2-2 Splice isoform 2 of Q86UP2 [Homo sapiens]           46  0.003
UniRef100_Q86UP2 Kinectin [Homo sapiens]                               46  0.003
UniRef100_Q54901 Precursor to Protein Sir22 precursor [Streptoco...    45  0.004
UniRef100_UPI000049A29E UPI000049A29E UniRef100 entry                  45  0.006
UniRef100_Q54745 Emm50 [Streptococcus pyogenes]                        45  0.007
UniRef100_UPI0000456A48 UPI0000456A48 UniRef100 entry                  44  0.010
UniRef100_UPI00001CF6F5 UPI00001CF6F5 UniRef100 entry                  44  0.010
UniRef100_Q7SHZ4 Hypothetical protein [Neurospora crassa]              44  0.010
UniRef100_P13050 IgA receptor precursor [Streptococcus pyogenes]       44  0.010
UniRef100_UPI0000437334 UPI0000437334 UniRef100 entry                  44  0.013
UniRef100_UPI000035EFFA UPI000035EFFA UniRef100 entry                  44  0.013
UniRef100_UPI000021BCCB UPI000021BCCB UniRef100 entry                  44  0.013

>UniRef100_UPI00001CFC7D UPI00001CFC7D UniRef100 entry
          Length = 1804

 Score = 51.2 bits (121), Expect = 8e-05
 Identities = 60/250 (24%), Positives = 111/250 (44%), Gaps = 16/250 (6%)

Query: 335  ENPKKKRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEK-------EARPNLG 387
            +N  K++ + + ++  N N ++Q T +K+ +    + E     ++K       + +    
Sbjct: 1337 QNTLKQKEKEEQQLQGNINQLKQATEQKKKQMEALQGELKNVTSQKAQLESKLQQQAAQA 1396

Query: 388  EKEKEVPSDPSTMLRDATDHVEFLLSRINHDYL--EKEVFGKGIDDAGQECVASLFHTGC 445
             +E  V     + L+   D  +  L ++  D    E E+     D    E   +L     
Sbjct: 1397 AQELAVEKGKLSALQSTYDKCQADLQQLQSDLYGKESELLATRQDLKCVEEKLALAQEDL 1456

Query: 446  IFAHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRL---DKVLTEAARDKITIDKKLVS 502
            I      + G      ++LQA   AL  + AK ++ L    K L +A R+K   +K+LV+
Sbjct: 1457 ISNR--NQIGNQNKSIQELQAAKAALEQDLAKKEEVLKEQSKALQDAQREKSVKEKELVT 1514

Query: 503  IANELVEARFELVCRSER-ITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELE 561
              ++L E   E+ CR E+ I  L+EE+K  KQE+   +    DA  L  Q+   L+ +++
Sbjct: 1515 EKSKLAEME-EIKCRQEKEIAKLKEELKSHKQESIKEVTNLKDAKQLLIQQKLELQGKVD 1573

Query: 562  EKKRDLLKKK 571
              K  L ++K
Sbjct: 1574 SLKAALEQEK 1583


>UniRef100_UPI000023F6CB UPI000023F6CB UniRef100 entry
          Length = 1493

 Score = 49.3 bits (116), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 4/110 (3%)

Query: 461  GEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER 520
            GEKL+A  T +     +     +++     R K+  +K+ V +  +  ++  EL   S  
Sbjct: 1017 GEKLRAQRTKVDAIKEEISSNNEEISNAEVR-KVKAEKQKVKLEKDHAKSSKELAAASRD 1075

Query: 521  ITDLEEEIK---ETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
            +  LE +I    E  +E Q  +A  ++ LA K QEL +L+AEL+EK  +L
Sbjct: 1076 LEKLENDINNQGERAEELQAQVAEAEEGLATKKQELKALKAELDEKTDEL 1125


>UniRef100_Q6DIC2 Early endosome antigen 1 [Mus musculus]
          Length = 1411

 Score = 49.3 bits (116), Expect = 3e-04
 Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)

Query: 462  EKLQADYTALRTEHAKCDDRL---DKVLTEAARDKITIDKKLVSIANELVEARFELVCRS 518
            ++LQA   +L  + AK +  L    K L +A R+K   +K+LV+  ++L E   E+ CR 
Sbjct: 1078 QELQAAKASLEQDSAKKEALLKEQSKALEDAQREKSVKEKELVAEKSKLAEME-EIKCRQ 1136

Query: 519  ER-ITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
            E+ IT L EE+K  KQE+   +    DA  L  Q+   L+  ++  K  L ++K
Sbjct: 1137 EKEITKLNEELKSHKQESIKEITNLKDAKQLLIQQKLELQGRVDSLKAALEQEK 1190



 Score = 37.0 bits (84), Expect = 1.6
 Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 24/119 (20%)

Query: 460 EGEKLQADYTALRTEHAKCDDRLDKVLTE-----AARDKI-----TIDKKLVSIANELVE 509
           E EKL  D    +T+H +  DR+   +TE     A +D +     T  +KL  +++ L  
Sbjct: 815 EFEKLSQDS---KTQHKELGDRMQAAVTELTAVKAQKDALLAELSTTKEKLSKVSDSLKN 871

Query: 510 ARFELVCRSER----ITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKK 564
           ++ E    +++    + DLE+  KE K + Q+   +     ALK+QE   L+  LE++K
Sbjct: 872 SKSEFEKENQKGKAAVLDLEKACKELKHQLQVQAES-----ALKEQE--DLKKSLEKEK 923


>UniRef100_UPI0000361937 UPI0000361937 UniRef100 entry
          Length = 1370

 Score = 48.5 bits (114), Expect = 5e-04
 Identities = 84/391 (21%), Positives = 148/391 (37%), Gaps = 55/391 (14%)

Query: 220 DAKSLKAKGWVSLKARMGRKCLNPFKSNAKTSFSQKYFMVAVHQAYPEVFTLRDG--TAS 277
           DAK L        K R+GR  ++  K +A    +Q  F +      P V  L     T++
Sbjct: 300 DAKDLICAFLSDRKVRLGRNGVDDIKRHAFFQNNQWTFDIIRETVAPVVPELSSDIDTSN 359

Query: 278 FPFYWTDKPNGIVDPPVDSLTVEDKTIIGF--FAQLPILDCSKLAAARRLAKFPPNFNTE 335
           F     DK N    PP  +        +GF  F +  +L  +    A        N   +
Sbjct: 360 FDDIENDKGNAETFPPPRAFVGNQLPFVGFTYFKEDQLLKANNKYLAEDSKDGEENSENK 419

Query: 336 NP------KKKRHQRDNEV-------------CENSNPV---------RQGTGEKESRTA 367
                   +KK HQ + ++             C+N+            ++ +G ++   +
Sbjct: 420 ESDTNTELQKKLHQLEEQLDCEMQAKDELEQKCKNATNRLEKLVKELDKEMSGRQKVEAS 479

Query: 368 LREKEGHFDLAEKEARPNLGEKEKEVPSDPS--TMLRDATDHVEFLLSRINHDYLEKEV- 424
           LR+ E    L + ++  NL + E E     S    L +  D +E L  +  +  +  E  
Sbjct: 480 LRQLERERALLQHQSVENLRKVELETDRKRSLENELNNLRDQLEDLRKKNQNSQISNEKN 539

Query: 425 --FGKGIDDAGQECVASLFHTGCIFAHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRL 482
               K +DD      A           A  +   S AE +K      A   E  +   +L
Sbjct: 540 IQLQKQLDDTNAGLQAE--------QEAAARLKKSQAEAQKQAQSLEASLGETKERCSQL 591

Query: 483 DKVLTEAARDKITIDKKLVSIANELVEARFELVCRSERITDLEEEIKETKQEAQLALAAK 542
           +K       D++ ++K+L ++  EL E R +   R+E I DL+  +   K+E +   ++ 
Sbjct: 592 EK-------DRMELEKQLTALQAELDEERRDGNLRTETIADLQGRVGRLKEEVKEVKSSH 644

Query: 543 DDALALK---DQELTSLRAELEEKKRDLLKK 570
            + L+ K    ++L  L  E   ++ DL+ K
Sbjct: 645 SEVLSEKKKLQEQLGILEKEKSNQEIDLMFK 675


>UniRef100_P16947 M protein, serotype 49 precursor [Streptococcus pyogenes]
          Length = 389

 Score = 47.0 bits (110), Expect = 0.002
 Identities = 58/239 (24%), Positives = 106/239 (44%), Gaps = 31/239 (12%)

Query: 340 KRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFD-----LAEKEARPNLGEKEKEVP 394
           K+HQ   +  E     RQ   E+  R   RE E  +        + E    + E  ++  
Sbjct: 115 KKHQEYKQEQEE----RQKNQEQLERKYQREVEKRYQEQLQKQQQLETEKQISEASRKSL 170

Query: 395 SDPSTMLRDATDHVEFLLSRIN--HDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQ 452
           S      R+A   VE  L+ +   H  L++E   K I DA ++ ++             +
Sbjct: 171 SRDLEASREAKKKVEADLAALTAEHQKLKEE---KQISDASRQGLS-------------R 214

Query: 453 KFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARF 512
              AS    +K++AD  AL  EH K  +  +K +++A+R  ++ D +    A + VEA  
Sbjct: 215 DLEASREAKKKVEADLAALTAEHQKLKE--EKQISDASRQGLSRDLEASREAKKKVEA-- 270

Query: 513 ELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
           +L   + ++  LE+  KE ++  +L+   K +  A  + E  +L+ +L ++  +L K K
Sbjct: 271 DLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLK 329


>UniRef100_UPI0000369CDB UPI0000369CDB UniRef100 entry
          Length = 1298

 Score = 46.2 bits (108), Expect = 0.003
 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 32/221 (14%)

Query: 371 KEGHFDLAEKEARPNLGEKEKE--VPSDPSTMLRDATDHVEFLLS-RINHDYLEKEVFGK 427
           K+    L E++ +  +  K +E  + +D +  L+     ++ L+S + N D +E+     
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737

Query: 428 GIDDAGQECVASLFHTGCI-FAHAFQKFGASTAEGEKLQADYTALRTEH------AKCDD 480
              D   + V  L  TG I  A   ++  A   E   L  +   L+ +       A   +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 481 RLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER-ITDLEEEIKETKQEA---- 535
            L KV+ E        D K+ S+  EL+EA    V   E+ + DL++EIK  K+E     
Sbjct: 798 ELKKVIHEK-------DGKIKSV-EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ 849

Query: 536 -----QLALAAK----DDALALKDQELTSLRAELEEKKRDL 567
                QL++ +K     + L  K++++ +++A LEEK++DL
Sbjct: 850 LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDL 890


>UniRef100_UPI0000369CDA UPI0000369CDA UniRef100 entry
          Length = 1355

 Score = 46.2 bits (108), Expect = 0.003
 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 32/221 (14%)

Query: 371 KEGHFDLAEKEARPNLGEKEKE--VPSDPSTMLRDATDHVEFLLS-RINHDYLEKEVFGK 427
           K+    L E++ +  +  K +E  + +D +  L+     ++ L+S + N D +E+     
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737

Query: 428 GIDDAGQECVASLFHTGCI-FAHAFQKFGASTAEGEKLQADYTALRTEH------AKCDD 480
              D   + V  L  TG I  A   ++  A   E   L  +   L+ +       A   +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 481 RLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER-ITDLEEEIKETKQEA---- 535
            L KV+ E        D K+ S+  EL+EA    V   E+ + DL++EIK  K+E     
Sbjct: 798 ELKKVIHEK-------DGKIKSV-EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ 849

Query: 536 -----QLALAAK----DDALALKDQELTSLRAELEEKKRDL 567
                QL++ +K     + L  K++++ +++A LEEK++DL
Sbjct: 850 LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDL 890


>UniRef100_Q658F8 Hypothetical protein P0015E04.9 [Oryza sativa]
          Length = 569

 Score = 46.2 bits (108), Expect = 0.003
 Identities = 47/180 (26%), Positives = 67/180 (37%), Gaps = 27/180 (15%)

Query: 164 IKFPFSSFFCDVLADINVAPCQLHPNAWAFMRCFEILCVAIQVTPSPV-------HFFYL 216
           ++ P   FF  VLA   +AP QL PNAW  +  F  LC    V P P        HFF  
Sbjct: 98  MRLPLQPFFAAVLAHFGLAPSQLTPNAWRLLAGFAALCRRAGVAPPPPPPLTVFRHFF-- 155

Query: 217 YDVDAKSLKAKGWVSLKARMGRKCLNPFKSNAKTSFSQKYFMVAVHQAYPEVFTLRDGTA 276
               A       W S +AR          S +  S   +   V ++  + E F L    A
Sbjct: 156 ---TAIGCPPGAWYSFRAR---------GSASTGSLFTRLSNVTMNPWWKEQFILVSSPA 203

Query: 277 SF--PFYWTDKPNGIVDPPVDSLTVEDKTIIGFFAQ----LPILDCSKLAAARRLAKFPP 330
            +  P  W         PPV +   +D       A+    + +   + +AAA+ +   PP
Sbjct: 204 PWPCPVRWGKPRKHANFPPVLTTAEKDMATKLLLARGSSLIDLTTYNSIAAAKNIIAPPP 263


>UniRef100_Q86UP2-2 Splice isoform 2 of Q86UP2 [Homo sapiens]
          Length = 1300

 Score = 46.2 bits (108), Expect = 0.003
 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 32/221 (14%)

Query: 371 KEGHFDLAEKEARPNLGEKEKE--VPSDPSTMLRDATDHVEFLLS-RINHDYLEKEVFGK 427
           K+    L E++ +  +  K +E  + +D +  L+     ++ L+S + N D +E+     
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737

Query: 428 GIDDAGQECVASLFHTGCI-FAHAFQKFGASTAEGEKLQADYTALRTEH------AKCDD 480
              D   + V  L  TG I  A   ++  A   E   L  +   L+ +       A   +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 481 RLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER-ITDLEEEIKETKQEA---- 535
            L KV+ E        D K+ S+  EL+EA    V   E+ + DL++EIK  K+E     
Sbjct: 798 ELKKVIHEK-------DGKIKSV-EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ 849

Query: 536 -----QLALAAK----DDALALKDQELTSLRAELEEKKRDL 567
                QL++ +K     + L  K++++ +++A LEEK++DL
Sbjct: 850 LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDL 890


>UniRef100_Q86UP2 Kinectin [Homo sapiens]
          Length = 1357

 Score = 46.2 bits (108), Expect = 0.003
 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 32/221 (14%)

Query: 371 KEGHFDLAEKEARPNLGEKEKE--VPSDPSTMLRDATDHVEFLLS-RINHDYLEKEVFGK 427
           K+    L E++ +  +  K +E  + +D +  L+     ++ L+S + N D +E+     
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737

Query: 428 GIDDAGQECVASLFHTGCI-FAHAFQKFGASTAEGEKLQADYTALRTEH------AKCDD 480
              D   + V  L  TG I  A   ++  A   E   L  +   L+ +       A   +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 481 RLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER-ITDLEEEIKETKQEA---- 535
            L KV+ E        D K+ S+  EL+EA    V   E+ + DL++EIK  K+E     
Sbjct: 798 ELKKVIHEK-------DGKIKSV-EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ 849

Query: 536 -----QLALAAK----DDALALKDQELTSLRAELEEKKRDL 567
                QL++ +K     + L  K++++ +++A LEEK++DL
Sbjct: 850 LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDL 890


>UniRef100_Q54901 Precursor to Protein Sir22 precursor [Streptococcus pyogenes]
          Length = 365

 Score = 45.4 bits (106), Expect = 0.004
 Identities = 47/214 (21%), Positives = 99/214 (45%), Gaps = 24/214 (11%)

Query: 376 DLAEKEARPNLGEKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQE 435
           DL EKE +    +K K++      + + + D     L +++ ++ E++   K +++  ++
Sbjct: 98  DLREKERKYQ--DKIKKLEEKEKNLEKKSEDVERHYLKKLDQEHKEQQERQKNLEELERQ 155

Query: 436 CVASL-------------FHTGCIFAHAFQK-----FGASTAEGEKLQADYTALRTEHAK 477
               +               T    + A +K       AS A  +K++AD  AL  EH K
Sbjct: 156 SQREIDKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKKVEADLAALNAEHQK 215

Query: 478 CDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSERITDLEEEIKETKQEAQL 537
             +  +K +++A+R  ++ D +    A + VEA  +L   + ++  LE+  KE ++  +L
Sbjct: 216 LKE--EKQISDASRQGLSRDLEASREAKKKVEA--DLAEANSKLQALEKLNKELEEGKKL 271

Query: 538 ALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
           +   K +  A  + E  +L+ +L ++  +L K K
Sbjct: 272 SEKEKAELQARLEAEAKALKEQLAKQAEELAKLK 305


>UniRef100_UPI000049A29E UPI000049A29E UniRef100 entry
          Length = 1813

 Score = 45.1 bits (105), Expect = 0.006
 Identities = 50/231 (21%), Positives = 102/231 (43%), Gaps = 26/231 (11%)

Query: 341 RHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPSDPSTM 400
           +++RDN +    N  ++   +KE+ T    +E    L E     N  ++EK+   D   +
Sbjct: 653 KNERDN-ISNEFNKTKEEIKQKENETIQLNEEKSVLLNEL----NQIKEEKQKIEDEKAV 707

Query: 401 LRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFGASTAE 460
           ++   ++    ++++N D    E     I    QE    L  T                E
Sbjct: 708 IQQEKENE---ITKLNEDKTVIENELNQIKTEKQEIENELNQT--------------KDE 750

Query: 461 GEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSER 520
            +K++ + + L TE +  +D + K+  E  + K    ++  ++ NEL + + E     E+
Sbjct: 751 KQKIEDEKSKLITELSNGNDGISKLNEELTQTK----QEKENVLNELNQIKNEFASFKEQ 806

Query: 521 ITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
            T  E E+K+   + Q  L  K++ ++  ++E  ++  EL   K++L +KK
Sbjct: 807 NTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKK 857



 Score = 41.2 bits (95), Expect = 0.083
 Identities = 33/183 (18%), Positives = 82/183 (44%), Gaps = 29/183 (15%)

Query: 388 EKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIF 447
           ++EKE  ++  T L+   D  E  L+++ H+  E                          
Sbjct: 267 KQEKESINNELTQLKTDNDQKENELNQVRHEKDE-------------------------- 300

Query: 448 AHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANEL 507
               +KF  S  E EK+  + + L+ E  + ++ L + + +   +K  +  +L + ++ +
Sbjct: 301 --VIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGI 358

Query: 508 VEARFELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
            +   EL    +   ++  E+   K+E +  +  + + +  +++E+   + ++EE+K++L
Sbjct: 359 SKLNEELTQTKQEKEEINNELNSIKEEKK-RIEEEKNQIINENKEIKEEKEKIEEEKKEL 417

Query: 568 LKK 570
           LK+
Sbjct: 418 LKE 420



 Score = 40.8 bits (94), Expect = 0.11
 Identities = 50/253 (19%), Positives = 109/253 (42%), Gaps = 27/253 (10%)

Query: 343  QRDNEVCENSNPVRQGTGEK----ESRTALREKEGHFDLAEKEARPNLG-------EKEK 391
            +RD  + E ++   Q  G K    E+   + E +  F+ +E E   +L        EKEK
Sbjct: 1052 ERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEK 1111

Query: 392  EVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHT-GCIFAHA 450
            ++ ++    L+         L  +  D +E +     I++  ++CV    +     +   
Sbjct: 1112 QM-NEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEE-KDCVEQERNKINEEYKTV 1169

Query: 451  FQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEA 510
             ++   +  E   LQ  Y     E  K  D L+ ++     +K  +++++  +  E  + 
Sbjct: 1170 NEELEKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKL 1229

Query: 511  RFELVCRSERITDLEEEIKETKQEAQ-------------LALAAKDDALALKDQELTSLR 557
              EL   S+ ++ L EE+ +TKQE +               +  + + +  +++E+   +
Sbjct: 1230 ITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEK 1289

Query: 558  AELEEKKRDLLKK 570
             ++EE+K++LLK+
Sbjct: 1290 EKIEEEKKELLKE 1302



 Score = 39.3 bits (90), Expect = 0.31
 Identities = 52/251 (20%), Positives = 104/251 (40%), Gaps = 28/251 (11%)

Query: 338  KKKRHQRDNEVCENSNPVRQGTGEKESRTA-LREKEGHFDLAEKEARPNLGEKEKEV--- 393
            K++  Q++NE+ + +N V+Q   +K +  + L E++G+        +  L +K++E+   
Sbjct: 804  KEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITI 863

Query: 394  ---PSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHA 450
                 +    L++    +E   S++     E      GI    +E   +           
Sbjct: 864  TQEKEEKENELKEQVKKIEEEKSKL---ITELSNGSDGISKLNEELTQTKQEK-----EE 915

Query: 451  FQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKL---VSIANEL 507
             QK  A   E EKL+   T L+ E  +    L++   +   +K  + ++L     I  EL
Sbjct: 916  IQK--ALEEEKEKLERIETELK-EIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEEL 972

Query: 508  VEARFELVCRSERITDLEEEIKETKQEAQLALAAKDD-------ALALKDQELTSLRAEL 560
             + + E    +  +  ++EE K  ++E    +    +       ++  K QE+ SL   +
Sbjct: 973  TQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSI 1032

Query: 561  EEKKRDLLKKK 571
            EE K  L + K
Sbjct: 1033 EELKGRLEESK 1043



 Score = 35.8 bits (81), Expect = 3.5
 Identities = 43/221 (19%), Positives = 95/221 (42%), Gaps = 15/221 (6%)

Query: 346  NEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPSDPSTMLRDAT 405
            N++ E+ N ++    E   +    + E +   +E E   N    EKE        L+   
Sbjct: 1441 NQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEG-------LKQVN 1493

Query: 406  DHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFGASTAEGEKLQ 465
            + V  +  +   D L K++  K I++  ++    L   G   +   ++      E E+L 
Sbjct: 1494 EEVNAI--KEERDELVKQI--KKIEEEKRKVEEELNFNG---SEVNEQIAQINNEKEQLN 1546

Query: 466  ADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELVCRSERITDLE 525
             +   L+    +   +++++  E   ++I   ++L  +  E+ E   ++    E I  +E
Sbjct: 1547 QECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIE 1606

Query: 526  EEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRD 566
            +E++E K+E    ++   + L     +LT  +  LEE+K++
Sbjct: 1607 KELQE-KEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKE 1646



 Score = 34.7 bits (78), Expect = 7.7
 Identities = 53/263 (20%), Positives = 106/263 (40%), Gaps = 53/263 (20%)

Query: 334 TENPKKK------RHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLG 387
           T+N +K+      RH++D EV E  N        KE    +  +       ++E    L 
Sbjct: 282 TDNDQKENELNQVRHEKD-EVIEKFNT------SKEENEKIMNELSQLKQEKEEKENELK 334

Query: 388 EKEKEVPSDPS---TMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTG 444
           E+ K++  + S   T L + +D +  L   +     EKE     ++   +E         
Sbjct: 335 EQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIKEE--------- 385

Query: 445 CIFAHAFQKFGASTAEGEKLQA--DYTALRTEHAKCDDRLDKVLTEAARDKI---TIDKK 499
                          E EK Q   +   ++ E  K ++   ++L E  ++K     +  +
Sbjct: 386 -----------KKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 434

Query: 500 LVSIAN---ELVEARFELVCRS--------ERITDLEEEIKETKQEAQLALAAKDDALAL 548
           + +I     E+ E   E++C +        E   +L++E+ + K+E Q     K++ + +
Sbjct: 435 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDV 494

Query: 549 KDQELTSLRAELEEKKRDLLKKK 571
           K Q+   L  +L+E+K  +  +K
Sbjct: 495 KTQKENELN-KLKEEKEQIFNEK 516


>UniRef100_Q54745 Emm50 [Streptococcus pyogenes]
          Length = 413

 Score = 44.7 bits (104), Expect = 0.007
 Identities = 54/236 (22%), Positives = 111/236 (46%), Gaps = 25/236 (10%)

Query: 338 KKKRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPSDP 397
           K+++ +++ ++ E S        E  SR A +E E      ++E +  + +  ++  S  
Sbjct: 141 KQQQLEKEKQISEASRKSLSRDLEA-SRAAKKELEAEHQKLKEEKQ--ISDASRQGLSRD 197

Query: 398 STMLRDATDHVEFLLSRIN--HDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFG 455
               R+A   VE  L+ +   H  L++E   K I +A ++ ++             +   
Sbjct: 198 LEASREAKKKVEADLAALTAEHQKLKEE---KQISEASRQGLS-------------RDLE 241

Query: 456 ASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELV 515
           AS    +K++AD  AL  EH K  +  +K +++A+R  ++ D +    A + VEA  +L 
Sbjct: 242 ASREAKKKVEADLAALTAEHQKLKE--EKQISDASRQGLSRDLEASREAKKKVEA--DLA 297

Query: 516 CRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
             + ++  LE+  KE ++  +L+   K +  A  + E  +L+ +L ++  +L K K
Sbjct: 298 EANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLK 353


>UniRef100_UPI0000456A48 UPI0000456A48 UniRef100 entry
          Length = 1143

 Score = 44.3 bits (103), Expect = 0.010
 Identities = 53/266 (19%), Positives = 110/266 (40%), Gaps = 27/266 (10%)

Query: 315  DCSKLAAARRLAKFPPNFNTENPKKKRHQRDNEVCENSNPVRQGTGEKESRTA----LRE 370
            +C K+   ++  K+      +  +  R+  D  V E ++  +Q + E+++R      L  
Sbjct: 782  ECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTS 841

Query: 371  KEGHFDLAEKEARPNLGEKEKEVPSDPSTMLRDATDHVEFLLSRINH-----DYLEKEVF 425
            K+   ++A+K+         K + ++    +    +  + L+   NH     D  EKE  
Sbjct: 842  KQKELEMAQKKMNSEFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKA 901

Query: 426  GKGID-DAGQECVASLFHTGCIFAHAFQKFGASTAEGEKLQADYT--ALRTEHAKCDDRL 482
            G+ ID    QE V S     C+   A         E E LQ   T  +++    +C+  L
Sbjct: 902  GRKIDLTEAQETVPSR----CLHLDA---------ENEVLQLQQTLFSMKAIQKQCET-L 947

Query: 483  DKVLTEAARDKITIDKKLVSIANELVEA-RFELVCRSERITDLEEEIKETKQEAQLALAA 541
             K   +  ++ + +   +     E  E  R +L+       +++E++ E     Q+A  +
Sbjct: 948  QKNKKQLKQEVVNLKSYMERNMLERGEGERHKLLIEERARKEIQEKLNEAVLTLQVAAVS 1007

Query: 542  KDDALALKDQELTSLRAELEEKKRDL 567
             +    L++   TS++ ++E   +DL
Sbjct: 1008 HEQLAQLREDNTTSIKTQMELTIKDL 1033


>UniRef100_UPI00001CF6F5 UPI00001CF6F5 UniRef100 entry
          Length = 1253

 Score = 44.3 bits (103), Expect = 0.010
 Identities = 44/189 (23%), Positives = 87/189 (45%), Gaps = 21/189 (11%)

Query: 388 EKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEK-----EVFGKGIDDAGQECVASLFH 442
           E+ K+   + S+ + +  D +  L+ R N  Y+E+     E     +  A +   A + H
Sbjct: 572 ERLKQELLEKSSRIEEQNDKISDLIER-NQRYVEQSNLMMEKRNNSLQTATENTQARILH 630

Query: 443 TGCIFAHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVS 502
                A   ++  A+TA+   LQ   TA    H K +  L   LTE  ++   +  ++  
Sbjct: 631 AEQEKAKVTEELAAATAQVSHLQLKMTA----HQKKETELQLQLTENLKETDLLRGQVTR 686

Query: 503 IANELVEARFELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEE 562
           +  +L+E R      SE+     +  K+++++ +L + + ++       ELT LRAE E 
Sbjct: 687 LQADLLELREA----SEQTQTKFKSEKQSRRQLELKVTSLEE-------ELTDLRAEKES 735

Query: 563 KKRDLLKKK 571
            +++L ++K
Sbjct: 736 LEKNLSERK 744


>UniRef100_Q7SHZ4 Hypothetical protein [Neurospora crassa]
          Length = 4007

 Score = 44.3 bits (103), Expect = 0.010
 Identities = 58/259 (22%), Positives = 101/259 (38%), Gaps = 39/259 (15%)

Query: 339  KKRHQRDNEVCENSNPVRQGTGEKE--------------------SRTALREKEGHFDLA 378
            K RH ++ E+    +  R G  E E                    S+ A++ K+   +LA
Sbjct: 1151 KNRHLQETEILRKQHQSRVGELESEIATIKEKYKKDLDELSRNNTSQDAIKLKQHENELA 1210

Query: 379  EKEARPNLGEKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVA 438
              +A+    +++K++     T +   TD            Y EKE       +  Q   A
Sbjct: 1211 NFKAKYE--QEKKQLAVQHKTEMESLTDR-----------YHEKEKLATQYQERVQALSA 1257

Query: 439  SLFHTGCIFAHAFQKFGASTAEGEKLQADYTALRTE-HAKCDDRLDKVLTEAARDKITID 497
             L       A   ++  AS A+ +KL+AD+     E  AK    + KV  +   +   + 
Sbjct: 1258 ELADKKTALAEYKEQLSASKAQLDKLKADHGVKVDELQAKLKSEVAKVTADYEGNLSELR 1317

Query: 498  KKLVSIANELV-----EARFELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQE 552
             K     N L      E +      +E+I +LE  I + K E +   A  D   AL + E
Sbjct: 1318 TKHQGEVNVLKVHHQDEIKKLTAGHNEKIRNLEHRINDLKAELKQDRAEFDKKKALLEGE 1377

Query: 553  LTSLRAELEEKKRDLLKKK 571
            + +L+ ++++K   L  K+
Sbjct: 1378 VATLQGKVDDKSSKLSSKE 1396



 Score = 37.0 bits (84), Expect = 1.6
 Identities = 32/121 (26%), Positives = 51/121 (41%), Gaps = 13/121 (10%)

Query: 463  KLQADYTALRTEHAKCDDRL---DKVLTEAARDKITIDKKLVSIANELVEARFELVCRSE 519
            KL  D   L+T+  K    L   D  LT+ A +  + D  L  +  EL      L  ++E
Sbjct: 2508 KLNKDIFDLKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAKKTE 2567

Query: 520  RITDLEEEIKETKQEA----------QLALAAKDDALALKDQELTSLRAELEEKKRDLLK 569
              + LE+ +K+   EA             LA   DA++  ++++  L  EL  K   L +
Sbjct: 2568 EASSLEKNVKKLTDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLNQELSTKDASLTQ 2627

Query: 570  K 570
            K
Sbjct: 2628 K 2628



 Score = 37.0 bits (84), Expect = 1.6
 Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 11/131 (8%)

Query: 452  QKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEAR 511
            +K GA+T+  E+       L  +      +LD+   E    K     +   +   + + +
Sbjct: 1497 RKEGAATSSTEQNTVQLNKLNDDVKDKQKKLDEQQAELNNLKTKHQAETTDLNQTIKDTK 1556

Query: 512  FELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRA-----------EL 560
             +L  +   + DL+++ K+     +  +A K   LA K+ EL +L+A           E+
Sbjct: 1557 AKLKQKETELIDLKKKHKDRLDTLEKTIAEKQTTLAQKETELENLKAQNRTNMMNTNREI 1616

Query: 561  EEKKRDLLKKK 571
             +K  +LLKK+
Sbjct: 1617 GDKTAELLKKE 1627



 Score = 36.2 bits (82), Expect = 2.7
 Identities = 55/242 (22%), Positives = 103/242 (41%), Gaps = 43/242 (17%)

Query: 345  DNEVCENSNPVRQGTGEKESRTA----LREKEGHFDLAEKEARPNLGEKEKEVPSDPSTM 400
            + E+      + Q TGE  S+ A    LRE     ++  KE    L +K +E+     ++
Sbjct: 2615 NQELSTKDASLTQKTGEVGSKNAELAKLRE-----EIRVKETA--LAKKTEELKGLNQSV 2667

Query: 401  LRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFGASTAE 460
              DA D  +    +I  + LEKEV G   D      +  L         +F K   +   
Sbjct: 2668 --DAKD-TQLAQDKIKIERLEKEVKGLTAD------IVKLREDVAFKDKSFAKKAEAV-- 2716

Query: 461  GEKLQADYTALRTEHAKCDDR---LDKVLTEAARDKITIDKKLVSIANELVEARFE---- 513
             + L+AD T L +E AK        D  +    ++ +++ K +  + N+  ++  +    
Sbjct: 2717 -DHLKADITELNSEVAKLKKEGTNKDAAILGKEKELVSLRKAVRDLTNQAKQSAQDSKKS 2775

Query: 514  ----------LVCRSERITDLEEEI---KETKQEAQLALAAKDDALALKDQELTSLRAEL 560
                      L  + ++I +L++EI   K+T +E       +D  L+ K++EL  LR ++
Sbjct: 2776 AEDLANRDALLKEKEKKIFELQQEIQKVKDTAEELNQTTKTRDSTLSQKNEELRKLREQI 2835

Query: 561  EE 562
            ++
Sbjct: 2836 KQ 2837



 Score = 35.8 bits (81), Expect = 3.5
 Identities = 52/245 (21%), Positives = 102/245 (41%), Gaps = 31/245 (12%)

Query: 331  NFNTENPKKKRHQRDNEVCE--NSNPVRQGTGEK---ESRTALREKEGHFDLAEKEARPN 385
            N   ++ K K  Q++ E+ +    +  R  T EK   E +T L +KE   +  + + R N
Sbjct: 1549 NQTIKDTKAKLKQKETELIDLKKKHKDRLDTLEKTIAEKQTTLAQKETELENLKAQNRTN 1608

Query: 386  LGEKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGC 445
            +    +E+    + +L+   +  +    R  +D  +K   G    D              
Sbjct: 1609 MMNTNREIGDKTAELLKKEGELRDL---RQKYDDAQKLADGSKEKDLA------------ 1653

Query: 446  IFAHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIAN 505
              A   Q     T+E EK + D  AL  +      R+  + +  +  +  + KK   I++
Sbjct: 1654 -IAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLESSVSSKRADLKKKETEISD 1712

Query: 506  ELVEARFELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKR 565
              ++ ++E     E I  L  ++  + Q+A L  A +++  ALK    + L  +++EK  
Sbjct: 1713 --LKRQYE-----ENIKRLNNDL--SSQKATLT-AKENEIAALKSGNASRLSRDIQEKAS 1762

Query: 566  DLLKK 570
            +L +K
Sbjct: 1763 ELAQK 1767


>UniRef100_P13050 IgA receptor precursor [Streptococcus pyogenes]
          Length = 386

 Score = 44.3 bits (103), Expect = 0.010
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)

Query: 456 ASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELV 515
           AS    +K++AD  AL  EH K  +  DK +++A+R  ++ D +    A + VEA  +L 
Sbjct: 215 ASREAKKKVEADLAALTAEHQKLKE--DKQISDASRQGLSRDLEASREAKKKVEA--DLA 270

Query: 516 CRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
             + ++  LE+  KE ++  +L+   K +  A  + E  +L+ +L ++  +L K K
Sbjct: 271 EANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLK 326


>UniRef100_UPI0000437334 UPI0000437334 UniRef100 entry
          Length = 3065

 Score = 43.9 bits (102), Expect = 0.013
 Identities = 57/240 (23%), Positives = 101/240 (41%), Gaps = 13/240 (5%)

Query: 333 NTENPKKKRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLA-EKEARPNLGEKEK 391
           ++E  K+K   R++E+ +    + +  GE +   +  E      L  ++EA  N    EK
Sbjct: 454 DSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNENRDAESLKLDREAFEN----EK 509

Query: 392 EVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAF 451
           EV     T L    D +E +     HD    E     I     E    +  T        
Sbjct: 510 EVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLN 569

Query: 452 QKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEAR 511
           +K      + + +Q+D   L  E  K D  L+K  +E  + K  ++K+  +   E+ + R
Sbjct: 570 EKNRDIEEKIKSIQSDKDMLEKE--KHD--LEKTRSELYKVKEDLEKQKENTLAEIQKER 625

Query: 512 FELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKKK 571
            +L   +E IT    EIK  +++    +  K D L     E+ +L+ ELE++K  ++K +
Sbjct: 626 EDLEKMNENITREMHEIKHQEEQ----MNQKQDELDQLKTEIQNLQQELEKEKEIIMKDR 681



 Score = 38.1 bits (87), Expect = 0.70
 Identities = 52/261 (19%), Positives = 107/261 (40%), Gaps = 45/261 (17%)

Query: 337  PKKKRHQRDNEVCENSNP-VRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPS 395
            PK+K  + D +  E +   + +   + E     +EKE   +  E   +  +  KE E   
Sbjct: 2494 PKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIK 2553

Query: 396  DPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFG 455
                 +R   DH +    ++N D    E   + ++    E +                  
Sbjct: 2554 SQLERVRSEMDHEQ---KKLNDDKKMIEQEKEDLEKMKSEIMKQ---------------- 2594

Query: 456  ASTAEGEKLQADYTALRTEHAKCD-----DRLDKVLTEAARDKITI-------DKKLVSI 503
                E E+ + D    +T+  K D     + ++K++ E  + K  I       D +   I
Sbjct: 2595 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKI 2654

Query: 504  ANE---LVEARFELVCRSERITDLEEEIK---ETKQEAQLALAAKDDAL-------ALKD 550
            A+E   L++ + E    +ERI +++EEIK   ET +E ++ L  + + +         + 
Sbjct: 2655 ADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRK 2714

Query: 551  QELTSLRAELEEKKRDLLKKK 571
            ++L  +  ++ E+K+DL+ ++
Sbjct: 2715 EDLEKMSTDINEQKQDLMNQR 2735



 Score = 37.4 bits (85), Expect = 1.2
 Identities = 53/280 (18%), Positives = 112/280 (39%), Gaps = 61/280 (21%)

Query: 339  KKRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPSDPS 398
            K   Q +NE   N N +      K+ R  L+E E H +  ++E + ++ E+ + +  D  
Sbjct: 1898 KSELQNENERIRNLNEII-----KKERETLKEMEAHLEKKKEEIK-SVSEETRRLKEDLE 1951

Query: 399  TMLRDATDHVEFLLSR----------INHDYLEKEVFGKGIDDAGQECVASLFHTGCIFA 448
             M  D     + L+++          INH + + +   + ID+   +  + L        
Sbjct: 1952 KMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ---QRIDEFDAQIKSQLERVRSEID 2008

Query: 449  HAFQKFGASTAEGEKLQADYTALRTEHAKCDDRLDK------------------------ 484
            H  +K        E+ + D   +++E  K   ++++                        
Sbjct: 2009 HEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKE 2068

Query: 485  ------VLTEAARDKITIDKKLVSIANE--------LVEARFELVCRSERITDLEEEIKE 530
                  V  E  R  I + K+ + I  +        +V+ + +L   +ERI +++EEIK+
Sbjct: 2069 IVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKK 2128

Query: 531  TKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDLLKK 570
             K+     L   +  L  + +E+ S+  E + ++++ L+K
Sbjct: 2129 EKE----TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEK 2164



 Score = 36.2 bits (82), Expect = 2.7
 Identities = 46/237 (19%), Positives = 100/237 (41%), Gaps = 21/237 (8%)

Query: 336  NPKKKRHQRDNEVCENSNPVRQGTGEKESRTALREKEGHFDLAEKEARPNLGEKEKEVPS 395
            N +    Q   E+      ++Q   E E+    +EK       + E   N+ E+EK    
Sbjct: 2733 NQRDLLKQEREEMNHKLTQLQQRIDEFETTNLQKEKN------KTEELKNILEREKSELY 2786

Query: 396  DPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIFAHAFQKFG 455
                 ++     +E +   +  +    E     ++D  +  ++ L     +  H   K  
Sbjct: 2787 QEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRL----SMEKHEIDKLK 2842

Query: 456  AST-AEGEKLQADYTALRT---EHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEAR 511
                +E E ++ +   L+    E+     +LD  + +   DK++I ++     + L E +
Sbjct: 2843 TEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQRE----KDSLEEIK 2898

Query: 512  FELVCRSERITD-LEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
             +L  ++E++ + + + ++ T Q +Q A    DD    K++EL S+RA++E + + L
Sbjct: 2899 ADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDRE--KEEELRSMRADIERQAKIL 2953



 Score = 35.8 bits (81), Expect = 3.5
 Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 8/184 (4%)

Query: 388  EKEKEVPSDPSTMLRDATDHVEFLLSRINHDYLEKEVFGKGIDDAGQECVASLFHTGCIF 447
            E E+EV     T L    D +E +     HD    E     I     +    +  T    
Sbjct: 971  ENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKD 1030

Query: 448  AHAFQKFGASTAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANEL 507
                +K      + + +Q+D   L  E  K D  L+K  +E  + K  ++K+  +   ++
Sbjct: 1031 MVLNEKNRDIEKKIKSIQSDKDMLEKE--KHD--LEKTRSELYKVKEDLEKQKENTLAQI 1086

Query: 508  VEARFELVCRSERITDLEEEIKETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
             + R +L   +E IT    EIK  +++    +  K D L     E+ +L+ ELE++K  +
Sbjct: 1087 QKEREDLEKMNENITREMHEIKHQEEQ----MNQKQDELDQLKTEIQNLQQELEKEKEII 1142

Query: 568  LKKK 571
            +K +
Sbjct: 1143 MKAR 1146



 Score = 35.4 bits (80), Expect = 4.5
 Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 460  EGEKLQADYTALRTEHAKCD-----DRLDKVLTEAARDKITI-------DKKLVSIANE- 506
            E E+ + +    +T   KCD     + + K++ E    K  I       D +   IA+E 
Sbjct: 1832 EEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 1891

Query: 507  --LVEARFELVCRSERITDLEEEIK---ETKQEAQLALAAKDDALALKDQELTSLRAELE 561
              L++ + EL   +ERI +L E IK   ET +E +  L  K + +    +E   L+ +LE
Sbjct: 1892 DLLIQNKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLE 1951

Query: 562  EKKRDLLKK 570
            +   D+ K+
Sbjct: 1952 KMSTDVNKQ 1960


>UniRef100_UPI000035EFFA UPI000035EFFA UniRef100 entry
          Length = 1932

 Score = 43.9 bits (102), Expect = 0.013
 Identities = 35/111 (31%), Positives = 58/111 (51%), Gaps = 10/111 (9%)

Query: 458 TAEGEKLQADYTALRTEHAKCDDRLDKVLTEAARDKITIDKKLVSIANELVEARFELVCR 517
           +AE EK  A    ++ +  K  + L K L +    K  +++K+VS+  E  + + ++   
Sbjct: 842 SAEAEKEMAQ---MKEDFEKTKEDLAKALAK----KKELEEKMVSLLQEKNDLQLQIQSE 894

Query: 518 SERITDLEEEIKET-KQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
           SE ++D EE  +   K + QL   AK+ A  L+D+E   + AEL  KKR L
Sbjct: 895 SETLSDAEERCEGLIKAKIQLEAKAKETAERLEDEE--EINAELTAKKRKL 943


>UniRef100_UPI000021BCCB UPI000021BCCB UniRef100 entry
          Length = 1496

 Score = 43.9 bits (102), Expect = 0.013
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 9/113 (7%)

Query: 464  LQADYTALRTEHAKCDDRLDKVLTE------AARDKITIDKKLVSIANELVEARFELVCR 517
            +Q     LR + AK D   +++ T       A   K+  +K+ V +A +  +A  +L   
Sbjct: 1034 MQVGGEKLRAQRAKIDSLKEEIATHNEELSTAEVKKVKAEKQKVKLAKDHAKATKDLQAA 1093

Query: 518  SERITDLEEEIK---ETKQEAQLALAAKDDALALKDQELTSLRAELEEKKRDL 567
               +  L++EI+   +  +    A+    +AL +K +EL+ L+AEL+EK  +L
Sbjct: 1094 VRDLESLDDEIQNQGDKSESLSSAVEEAQEALKVKKKELSELKAELDEKTAEL 1146


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.320    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 976,425,483
Number of Sequences: 2790947
Number of extensions: 42977407
Number of successful extensions: 146093
Number of sequences better than 10.0: 1093
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 1031
Number of HSP's that attempted gapping in prelim test: 143324
Number of HSP's gapped (non-prelim): 3676
length of query: 571
length of database: 848,049,833
effective HSP length: 133
effective length of query: 438
effective length of database: 476,853,882
effective search space: 208862000316
effective search space used: 208862000316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 78 (34.7 bits)