BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0148.5
(586 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_UPI00002197A0 UPI00002197A0 UniRef100 entry 93 2e-17
UniRef100_Q06852 Cell surface glycoprotein 1 precursor [Clostrid... 80 1e-13
UniRef100_Q95YM2 I-connectin [Procambarus clarkii] 78 6e-13
UniRef100_O45544 Hypothetical protein F49E2.5d [Caenorhabditis e... 77 2e-12
UniRef100_O45543 Hypothetical protein F49E2.5f [Caenorhabditis e... 74 2e-11
UniRef100_UPI00004345B3 UPI00004345B3 UniRef100 entry 73 3e-11
UniRef100_UPI0000431AEB UPI0000431AEB UniRef100 entry 73 3e-11
UniRef100_UPI000023F701 UPI000023F701 UniRef100 entry 71 8e-11
UniRef100_Q96QC2 KIAA0170 protein [Homo sapiens] 71 1e-10
UniRef100_Q20626 Hypothetical protein F49E2.5a [Caenorhabditis e... 70 1e-10
UniRef100_Q5ST83 Mediator of DNA damage checkpoint 1 [Homo sapiens] 70 2e-10
UniRef100_Q86Z06 Homologue to Drosophila photoreceptor protein c... 70 2e-10
UniRef100_Q92954 Megakaryocyte stimulating factor [Homo sapiens] 69 3e-10
UniRef100_UPI0000431AED UPI0000431AED UniRef100 entry 69 4e-10
UniRef100_UPI0000431AEC UPI0000431AEC UniRef100 entry 69 4e-10
UniRef100_UPI000021B299 UPI000021B299 UniRef100 entry 68 7e-10
UniRef100_Q9JM99 Mus musculus [Mus musculus] 68 7e-10
UniRef100_Q7PF94 ENSANGP00000024414 [Anopheles gambiae str. PEST] 68 9e-10
UniRef100_Q14676 KIAA0170 protein [Homo sapiens] 68 9e-10
UniRef100_Q9BX49 Proteoglycan 4, [Homo sapiens] 68 9e-10
>UniRef100_UPI00002197A0 UPI00002197A0 UniRef100 entry
Length = 3106
Score = 92.8 bits (229), Expect = 2e-17
Identities = 131/607 (21%), Positives = 224/607 (36%), Gaps = 119/607 (19%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETP 78
E PLP E + E S KK +KKKK K + TA P LE
Sbjct: 731 ESVTPLPETELEAESLPSPKKDKKKKKKKGKS-----------------GTATP--LEAK 771
Query: 79 KEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHS-EPTQL 137
E AEP + P P Q P +++ + + L+ +PE EP+ + ++ EP
Sbjct: 772 AE--AEPEAKQEIEPEPKQEPEPEPKQEPEPDAQLKAEPELEPKQETVPDSQQEPEPVPS 829
Query: 138 CSVKK-KKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLG 196
S KK KKK+K +S A A + + PP + PEP+ K+ P + EP L
Sbjct: 830 ASSKKDKKKKKKGKSGTATPIEAIISSPPPEPEPKQEPEPELKQ---EPEPELKQEPELE 886
Query: 197 LAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPE-------KNKGENLTPTDE 249
L ++PE +++ E E + PEP + + +P+ K + E P
Sbjct: 887 LKQELEPEAKQEQEPEAELKQE---SAPEPDMKQGLEFEPKQEPKPEAKQEPEPAPPASS 943
Query: 250 NELDRRNRREELVALVTSDEKIVNPRD------HLVPLKSIPGFVLEQQT---------- 293
+ ++ ++++L A + + P P++++P +T
Sbjct: 944 KKDKKKKKKDKLAAAADETKSVGAPSPAEPALVEEAPIEAVPVAAEPVETAPVEAAAVEA 1003
Query: 294 ----QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRM------NSMPD 343
P P+ P +A+ + + V+T + +K + + S D
Sbjct: 1004 TPVEAPSPIEPNAAEAATAATAAVNVAPVETAPVEEASTEAEPLKAEPVGVETVDTSTLD 1063
Query: 344 KHNTEPPETKKRVL-DREE---PNKCNAKLPETLMLASNCHIDQA-IPSDSNPAVPTNPE 398
+ EP V D +E +K + K ++ +A D+A +P+++ +V E
Sbjct: 1064 AASAEPETLAAPVKPDTDELPSSSKKDKKKKKSKDVADVAPPDEAKVPTEAETSV--TEE 1121
Query: 399 HKTPKKWKKRAKKKN--------------------VLLSEGGKSNEHNGQPTETPVQKSV 438
TP + KK+ K K VL + K N+ G PV
Sbjct: 1122 AATPSRDKKKKKDKGADATPVEVVAAVEQQKPEPAVLSKKDKKKNKDKGASDPEPV---- 1177
Query: 439 SPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQK- 497
P + P + ++ +P K + K + + +E P T VQ+
Sbjct: 1178 -----PEVPPPVVQEEEIPASSQKDKKKKKKKDKGKADTE--AEVGDQASSPAATDVQEV 1230
Query: 498 ------------------SVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKK 539
V I AP I T P ++ P+ SK ++KK
Sbjct: 1231 AAPEVQELGNETSASAAPDVQEIAAPEIQELDKTSPPAASEVQDPEEDLKASSKKDKKKK 1290
Query: 540 NKRALKS 546
+A++S
Sbjct: 1291 KDKAIES 1297
Score = 78.2 bits (191), Expect = 6e-13
Identities = 123/606 (20%), Positives = 197/606 (32%), Gaps = 87/606 (14%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIK---------EEGIES 53
S + + K + ++ PEP P+ E E S SKKK+ KK + EE
Sbjct: 163 SEDEGDKKGKKSKSKKTDPEPAPADELALESSKSKKKKSKKAAAEPEPALEPPAEEEKAK 222
Query: 54 HEHDQVLLPEPVVVATAIPITLETPKEQGAEP-IEATVVHPVPDQ------RPAKTHRKK 106
E +V EP A + P EP A V P D + +K +KK
Sbjct: 223 DETKEVAADEPSAPADEPSAPADEPPAPSDEPSATAEVTSPAADDVVFEEVKKSKKDKKK 282
Query: 107 KKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPP 166
KK+ EP P P P P E + + KKKK +KGA + T PP
Sbjct: 283 SKKKGAEEPPPPPPPAPVEEVKSSKKD-------KKKKSKKGASDD----------TPPP 325
Query: 167 AVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEP 226
P P P E + P P P P + + +E +A+ A +P
Sbjct: 326 -------PPPAPAEEAAPAAPDTEPVPSAVEEPAAQPAEETAASSTDEKSADATPASEQP 378
Query: 227 PLGLAIPIDPEKN--KGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSI 284
+ +D + + E P +E E+ +A+ +++ + P+
Sbjct: 379 QADPEVAVDQKSDDPTSEEAAPA-ASETKPLEAAEDALAVAEAEKDAAVTEEAAAPVAES 437
Query: 285 PGFVLE------------QQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSK 332
+ Q+++ P P +A + P D + S+
Sbjct: 438 AAIEADGTAVAGKDAETPQKSEDPAEAPALPTAADAPAEDGPAPAAD--------APASE 489
Query: 333 MKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPA 392
+ + + PE E P P T + S + D+ P+ +
Sbjct: 490 QPTEPAPATEENTTERAPEEVDSTAKAEAP-------PVTEEIVSATNADEVAPTTAEAP 542
Query: 393 VPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDP---T 449
+N E K+ A + + + TE P P N + P
Sbjct: 543 ESSNAEAAVDLATKEEAPASSDDATPNKAEDATMPSATENPPAADAPPANVEEVPPPNDE 602
Query: 450 LPTDQPVPI-DLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSID 508
T +P P D AT + + A K++E QK + P +
Sbjct: 603 QATSKPDPANDEATKEEAPAASDKATPE--------KADELTFSIDEQKPATDAREPDVP 654
Query: 509 PTLPTDQP-VPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSS--DQNAKTPVQ 565
T D+P + A P E + + ++ K A S D A PV
Sbjct: 655 DT--KDEPAASSETAAPATEEAPATASAPAEETKAVADEAAPSDAKEESTPDSAAAAPVV 712
Query: 566 RTESLK 571
E+ K
Sbjct: 713 TEEAPK 718
Score = 63.5 bits (153), Expect = 2e-08
Identities = 125/549 (22%), Positives = 197/549 (35%), Gaps = 127/549 (23%)
Query: 18 EEKPEPLPS-----PEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
+ K EP S P ++ + + + K + +E S ++ P A A
Sbjct: 655 DTKDEPAASSETAAPATEEAPATASAPAEETKAVADEAAPSDAKEE---STPDSAAAAPV 711
Query: 73 ITLETPKEQ---GAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNT 129
+T E PK+Q P E+ V P+P ET LE + P P+
Sbjct: 712 VTEEAPKDQPVVAPPPTESESVTPLP--------------ETELEAESLPSPKKD----- 752
Query: 130 DHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRV 189
KKKKK+KG +S A A EP A Q + PEPK +EP P+
Sbjct: 753 -----------KKKKKKKG-KSGTATPLEAKAEAEPEAKQE-IEPEPK-QEP--EPEPKQ 796
Query: 190 CPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEP-PLGLAIPIDPEKNKGENLTPTD 248
PEP L K E EP + + PEP P + +K KG++ T T
Sbjct: 797 EPEPDAQL-------KAEPELEPKQETVPDSQQEPEPVPSASSKKDKKKKKKGKSGTAT- 848
Query: 249 ENELDRRNRREELVALVTSDEKIVNPRDHLVP---------LKSIPGFVLEQQTQPGPVI 299
+ A+++S P+ P LK P L+Q+ +P
Sbjct: 849 -----------PIEAIISSPPPEPEPKQEPEPELKQEPEPELKQEPELELKQELEPEAKQ 897
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDR 359
P + + ++ P D +Q + + + P PP + K+ +
Sbjct: 898 EQEPEAEL---KQESAPEPDMKQGLEFEPKQEPKPEAKQEPEP-----APPASSKKDKKK 949
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPA-VPTNPEHKTPKKWKKRAKKKNVLLSE 418
++ +K A ET + + PS + PA V P P
Sbjct: 950 KKKDKLAAAADETKSVGA--------PSPAEPALVEEAPIEAVPVA-------------- 987
Query: 419 GGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNV 478
+P ET +P+ A +++ T P + P PI+ P +E + NV
Sbjct: 988 --------AEPVET------APVEAAAVEAT-PVEAPSPIE---PNAAEAATAATAAVNV 1029
Query: 479 LLSEGVKSNEQPTETPVQKSVNPIKAPSID-PTLPTDQPVPIDLATP-KHSEGKMSKAQR 536
E E TE K+ P+ ++D TL P LA P K ++ + +
Sbjct: 1030 APVETAPVEEASTEAEPLKA-EPVGVETVDTSTLDAASAEPETLAAPVKPDTDELPSSSK 1088
Query: 537 RKKNKRALK 545
+ K K+ K
Sbjct: 1089 KDKKKKKSK 1097
Score = 62.8 bits (151), Expect = 3e-08
Identities = 104/544 (19%), Positives = 193/544 (35%), Gaps = 65/544 (11%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKI---KEEGIESHEHDQVLLPEPVVVAT 69
KK EE P PL + E SKKK + KK ++EG + + + +P A
Sbjct: 127 KKSAVEETPTPLVDDGEVLESPKSKKKSKGKKDAEISEDEGDKKGKKSKSKKTDP-EPAP 185
Query: 70 AIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP-------- 121
A + LE+ K +KKK K+ EP+P EP
Sbjct: 186 ADELALESSKS-----------------------KKKKSKKAAAEPEPALEPPAEEEKAK 222
Query: 122 -EPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEP---PAVQGGVLPEPK 177
E KE + + S P S + ++ A AE+ + + V+ + K
Sbjct: 223 DETKEVAADEPSAPADEPSAPADEPPAPSDEPSATAEVTSPAADDVVFEEVKKSKKDKKK 282
Query: 178 PKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPE 237
K+ + E P P PP + +K++K+ ++ + P P P A P P+
Sbjct: 283 SKKKGAEEPPP--PPPPAPVEEVKSSKKDKKKKSKKGASDDTPPPPPPAPAEEAAPAAPD 340
Query: 238 KNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGP 297
P + + E A ++DEK + ++ P ++Q++
Sbjct: 341 TE------PVPSAVEEPAAQPAEETAASSTDEKSADATPASEQPQADPEVAVDQKSDD-- 392
Query: 298 VIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVL 357
P +A +++ + + + + + + + + + + E T
Sbjct: 393 --PTSEEAAPAASETKPLEAAEDALAVAEAEKDAAVTEEAAAPVAESAAIEADGTAVAGK 450
Query: 358 DREEPNKCN--AKLPETLMLASNCHIDQA-----------IPSDSNPAVPTNPEHKTPKK 404
D E P K A+ P L A++ + P++ PA N + P++
Sbjct: 451 DAETPQKSEDPAEAP-ALPTAADAPAEDGPAPAADAPASEQPTEPAPATEENTTERAPEE 509
Query: 405 WKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPK 464
AK + ++E S + + T + S ++D + P D ATP
Sbjct: 510 VDSTAKAEAPPVTEEIVSATNADEVAPTTAEAPESSNAEAAVDLATKEEAPASSDDATPN 569
Query: 465 HSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATP 524
+E + N ++ +N + P + P+ D + P D ATP
Sbjct: 570 KAEDATMPSATENPPAADAPPANVEEVPPPNDEQATSKPDPANDEATKEEAPAASDKATP 629
Query: 525 KHSE 528
+ ++
Sbjct: 630 EKAD 633
Score = 56.2 bits (134), Expect = 3e-06
Identities = 119/564 (21%), Positives = 200/564 (35%), Gaps = 92/564 (16%)
Query: 9 LLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVA 68
++ S E K EP P +Q+ E + K+ + ++K+E
Sbjct: 853 IISSPPPEPEPKQEPEPELKQEPE---PELKQEPELELKQE------------------- 890
Query: 69 TAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSN 128
LE +Q EP P+ + + K+E E + EPEP P +S
Sbjct: 891 ------LEPEAKQEQEPEAELKQESAPEPDMKQGLEFEPKQEPKPEAKQEPEPAPPASSK 944
Query: 129 TDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPE-PKPKEPCSTEHP 187
D KKKK + A ++E + A EP V+ + P EP T
Sbjct: 945 KDKK--------KKKKDKLAAAADETKSVGAPSPAEPALVEEAPIEAVPVAAEPVETAPV 996
Query: 188 RVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLA-IPIDPEKNKGENLTP 246
+ P E N EA + A + P+ A +P K + +
Sbjct: 997 EAAAVEATPVEAPSPIEPNAAEAATAATAAVNVAPVETAPVEEASTEAEPLKAEPVGVET 1056
Query: 247 TDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSA 306
D + LD + E +A V P +P S ++ V P P+ A
Sbjct: 1057 VDTSTLDAASAEPETLAAP------VKPDTDELPSSSKKDKKKKKSKDVADVAP--PDEA 1108
Query: 307 SLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMP-------DKHNTEPPETKKRVLDR 359
+ +++T TE+ K K K ++ P ++ EP K+ D+
Sbjct: 1109 KVPTEAETSV---TEEAATPSRDKKKKKDKGADATPVEVVAAVEQQKPEPAVLSKK--DK 1163
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEG 419
++ A PE +P P V + +K KK+ KKK +
Sbjct: 1164 KKNKDKGASDPE------------PVPEVPPPVVQEEEIPASSQKDKKKKKKK-----DK 1206
Query: 420 GKSNEHN--GQPTETPVQKSVSPINAPSI----DPTLPTDQPVPIDLATP------KHSE 467
GK++ G +P V + AP + + T + P ++A P K S
Sbjct: 1207 GKADTEAEVGDQASSPAATDVQEVAAPEVQELGNETSASAAPDVQEIAAPEIQELDKTSP 1266
Query: 468 GKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHS 527
S Q L K +++ + +S P++A P LP ++ DL+T K
Sbjct: 1267 PAASEVQDPEEDLKASSKKDKKKKKDKAIES-TPVEA----PPLPKEEEPEEDLSTSKKK 1321
Query: 528 EGKMSKAQRRKKNKRALKSAWSES 551
K + ++K+K+ K S++
Sbjct: 1322 SKSKDKDKDQEKDKKGKKDKKSKA 1345
Score = 49.7 bits (117), Expect = 2e-04
Identities = 126/591 (21%), Positives = 204/591 (34%), Gaps = 88/591 (14%)
Query: 12 SKKRRREEK------PEPLPSPE----QDQEQSCSKKKRRKKKKIKEEG---IESHEHDQ 58
SKK +++ K PEP+P Q++E S +K +KKKK K++G E+ DQ
Sbjct: 1159 SKKDKKKNKDKGASDPEPVPEVPPPVVQEEEIPASSQKDKKKKKKKDKGKADTEAEVGDQ 1218
Query: 59 VLLPEPV-VVATAIPITLETPKEQGAE---------------------PIEATVVHPVPD 96
P V A P E E A P + V P D
Sbjct: 1219 ASSPAATDVQEVAAPEVQELGNETSASAAPDVQEIAAPEIQELDKTSPPAASEVQDPEED 1278
Query: 97 QRPAKTHRKKKKKETVLEPQP----------EPEPEPKETSNTDHSEPTQLCSVKKKKKR 146
+ + KKKKK+ +E P EPE + + S+ K KK +
Sbjct: 1279 LKASSKKDKKKKKDKAIESTPVEAPPLPKEEEPEEDLSTSKKKSKSKDKDKDQEKDKKGK 1338
Query: 147 KGAESNEAVAELATVCTEPPAV-QGGVLPEPKPKE--------PCSTEHPRVCPE---PP 194
K +S A P AV L +P++ + E P E PP
Sbjct: 1339 KDKKSKAGKTVAAAAAIAPAAVLAASALEADEPEDSQAADDSGAVNGEEPARAAEDNVPP 1398
Query: 195 LGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP-EKNKGENLTPTDENELD 253
+ +P + + E + A E P LA P + EN PT + D
Sbjct: 1399 VA-EVPSESVDTLESEESAATKDTVDVATGEEPAQLAAPDESGSPVSAENEPPTAAPQAD 1457
Query: 254 RRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFV----LEQQTQPGPVIPVCPNSASLI 309
++ A E + P D + P V LE + + P+S
Sbjct: 1458 DAAPKDS-EADPCEPEAPIKPADVESDVMQTPDVVSADALEPEKDAAEPLDGMPSSDLPR 1516
Query: 310 GQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKL 369
Q D E+ I M + + + T + +D P + L
Sbjct: 1517 DSEQNATSDDAEKTIPTEELGIGMSAEETDEKAVEVPTGDEQAAVEAVDAVPPQ--DGSL 1574
Query: 370 PETLMLASNCHIDQA--IPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNG 427
E + A ID A + + A PTN + + + A+ K E +
Sbjct: 1575 QEAAVEAEPVSIDAAPEVEPEVPSAEPTNVDDAAVAEEPQPAEPK-----EDQPAAPEGS 1629
Query: 428 QPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSN 487
T+ ++V+ P+ +P+ T +P P +P E AQ + ++G
Sbjct: 1630 DATQDTAPEAVAAGGEPAGEPSTAT-EPEPAS-ESPTADE---PTAQADVAPATDGSIDK 1684
Query: 488 EQPTETPVQKSVN--PIKAPSIDPTLPTD-------QPVPIDLATPKHSEG 529
+ + K+ + P KAP ++ ++P D PV + A+ + +G
Sbjct: 1685 SETLDEAQDKAGDEAPAKAPDVE-SVPKDASAAETLDPVSVPEASAQLDDG 1734
Score = 45.8 bits (107), Expect = 0.003
Identities = 92/452 (20%), Positives = 148/452 (32%), Gaps = 101/452 (22%)
Query: 72 PITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
P+ + G P E P K KK K+ + E PE + +
Sbjct: 50 PLDQNGDGQDGGIPAEEDEWPTTPLTAAQKKAAKKAAKKAAKKAGAEVVPETPKVEEPEV 109
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
+L + KKKK KG +S AV E T P G VL PK K+ +
Sbjct: 110 IPEEELAATGKKKKSKGKKS--AVEETPT----PLVDDGEVLESPKSKKKSKGKK----- 158
Query: 192 EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENE 251
D E + E + ++ + PEP P DE
Sbjct: 159 ----------DAEISEDEGDKKGKKSKSKKTDPEP------------------APADELA 190
Query: 252 LDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQ 311
L+ +++ S + P L P E++ V + S
Sbjct: 191 LESSKSKKK-----KSKKAAAEPEPALEP-------PAEEEKAKDETKEVAADEPSAPAD 238
Query: 312 SQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPE 371
+ P + ++ S +++ + P + E KK D+++ K A+ P
Sbjct: 239 EPSAPADEPPAPSDEPSATAEV------TSPAADDVVFEEVKKSKKDKKKSKKKGAEEPP 292
Query: 372 TLMLASNCHIDQAIPSDSNPAVPTNP--EHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQP 429
P P P E K+ KK KK+ KK G S++ P
Sbjct: 293 -------------------PPPPPAPVEEVKSSKKDKKKKSKK-------GASDDTPPPP 326
Query: 430 TETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQ 489
P +++ P P +PVP + P + + A + ++ ++EQ
Sbjct: 327 PPAPAEEAA---------PAAPDTEPVPSAVEEPAAQPAEETAASSTDEKSADATPASEQ 377
Query: 490 PTETPV----QKSVNPIK---APSIDPTLPTD 514
P P QKS +P AP+ T P +
Sbjct: 378 PQADPEVAVDQKSDDPTSEEAAPAASETKPLE 409
Score = 38.1 bits (87), Expect = 0.72
Identities = 57/255 (22%), Positives = 95/255 (36%), Gaps = 34/255 (13%)
Query: 21 PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKE 80
P +PE +E S + + ++++ ++ + PEPVV PI + P E
Sbjct: 2141 PAATQAPEDQEESSAAPEPATTSEEVEVAAGQTVLAPEA--PEPVVKDDITPIDGDIPAE 2198
Query: 81 QGAEPIEATVVHPVPDQRPAKTHRKKKKKE---------TVLEPQPEPEPEPKETSN--- 128
E + P + PA + ++ KE T +E P P+ E S+
Sbjct: 2199 ADVESGAKVDIEP---EIPASSAEVEESKEPGILAADAATEVEAAPAPQAEAMVASDEAV 2255
Query: 129 TDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHP- 187
++ L +V+ + E+ EA + A +E AV + P+EP +T P
Sbjct: 2256 AKEADDKSLDAVEAAQPPTEVETLEATGD-ADAVSEEKAV------DDIPEEPSNTAEPV 2308
Query: 188 --------RVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPL-GLAIPIDPEK 238
V + I +P EA ES AE + EP G E+
Sbjct: 2309 AEAATDIVDVNDSDAVSKEIEEEPAAEAAEAAARESLAEDSQVVEEPAAEGAVETAAVEE 2368
Query: 239 NKGENLTPTDENELD 253
K +P DE ++
Sbjct: 2369 PKAFEESPIDETVVE 2383
Score = 35.8 bits (81), Expect = 3.6
Identities = 46/183 (25%), Positives = 67/183 (36%), Gaps = 19/183 (10%)
Query: 52 ESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHP---VPDQRPAKTHRKKKK 108
ES D ++ EP +E PK PI+ TVV P P + + +
Sbjct: 2343 ESLAEDSQVVEEPAAEGAVETAAVEEPKAFEESPIDETVVEPATATESDVPHEDNSDEDA 2402
Query: 109 KETVLE-------PQPEPEPEPKETSNTDHSEPTQLCSVKKKKK------RKGAESNEAV 155
E +E Q E E + D EP S ++ ++ AE+ EA
Sbjct: 2403 PEAAVEAAAASDLAQTEAPEEAASAEDNDDKEPQAESSALAHEREPENEIKEPAEATEA- 2461
Query: 156 AELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNES 215
AE+ V TE + + E P E P V P LA P+ + EAE ++
Sbjct: 2462 AEMQAV-TEAESQADQTIGESLPSESEPEPTPEVASAPVPVLADETTPD-DAPEAEACQA 2519
Query: 216 NAE 218
E
Sbjct: 2520 TVE 2522
>UniRef100_Q06852 Cell surface glycoprotein 1 precursor [Clostridium thermocellum]
Length = 1664
Score = 80.5 bits (197), Expect = 1e-13
Identities = 112/477 (23%), Positives = 171/477 (35%), Gaps = 64/477 (13%)
Query: 59 VLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPE 118
V+ P P+ A+ PI +TP ++ E P P P + EP P
Sbjct: 759 VIQPAPIKAASDEPIPTDTPSDEPTPSDE-----PTPSDEPTPSD----------EPTPS 803
Query: 119 PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKP 178
EP P ET + PT S + + S+E ++ P P P
Sbjct: 804 DEPTPSETP--EEPIPTDTPSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETP 855
Query: 179 KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEK 238
+EP T+ P P P P ++ EP S+ P PE P+ P D E
Sbjct: 856 EEPIPTDTPSDEPTPS---DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EP 911
Query: 239 NKGENLTPTDE-NELDRRNRREELVALVTSDEKIVN--PRDHLVPL-KSIPGFVLEQQTQ 294
+ TP+DE D +E T +E I P D P + P +
Sbjct: 912 TPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDE 971
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN-TEPPETK 353
P P P+ T P E+ I + + + D+ ++ P
Sbjct: 972 PTPSDEPTPSDEPTPSDEPT-PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1030
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKN 413
+EP + P ++ IP+D+ PT + TP
Sbjct: 1031 DEPTPSDEPTPSDEPTPSETP-------EEPIPTDTPSDEPTPSDEPTPS---------- 1073
Query: 414 VLLSEGGKSNEH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMS 471
E S+E + +PT + + P + PS +PT P+D+P P D TP E S
Sbjct: 1074 ---DEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPS-DEPTPS 1128
Query: 472 NAQRNNVLLSEGVKSNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATPKHS 527
+ + E + PT+TP + + PS +PT P+D+P P D TP +
Sbjct: 1129 DEPTPSETPEEPI-----PTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTPSET 1179
Score = 79.0 bits (193), Expect = 4e-13
Identities = 114/520 (21%), Positives = 170/520 (31%), Gaps = 68/520 (13%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKI-KEEGIESHEHDQVLLPEPVVVATAIPITLE 76
E EP+P+ E + S + + +E S E PE PI +
Sbjct: 896 ETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEE-------PIPTD 948
Query: 77 TPKEQGAEPIEATVV-HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPT 135
TP ++ E T P P P + E +P P P+E TD
Sbjct: 949 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDE 1008
Query: 136 QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPL 195
S + + S+E ++ P P P+EP T+ P P P
Sbjct: 1009 PTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPS- 1067
Query: 196 GLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-NELDR 254
P ++ EP S+ P PE P+ P D E + TP+DE D
Sbjct: 1068 --DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPTPSDE 1124
Query: 255 RNRREELVALVTSDEKIVN--PRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQS 312
+E T +E I P D P +P P P+
Sbjct: 1125 PTPSDEPTPSETPEEPIPTDTPSDEPTP-----------SDEPTPSDEPTPSDEPTPSDE 1173
Query: 313 QTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPET 372
T P E+ I P ++ P +EP + P
Sbjct: 1174 PT-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPSDEPTPSDEPTPSD 1215
Query: 373 LMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEH--NGQPT 430
S ++ IP+D+ PT + TP E S+E + +PT
Sbjct: 1216 EPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEPTPSDEPTPSDEPT 1261
Query: 431 ETPVQKSVSPINAPSIDPT-----LPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVK 485
+ + P + PS +PT P+D+P P D TP ++
Sbjct: 1262 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETP 1321
Query: 486 SNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATP 524
PT+TP + + PS +PT P+D+P P D TP
Sbjct: 1322 EEPIPTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTP 1360
Score = 76.6 bits (187), Expect = 2e-12
Identities = 115/537 (21%), Positives = 171/537 (31%), Gaps = 77/537 (14%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP--------EPVVVATAIPI 73
EP PS E + + EE I + P EP P
Sbjct: 830 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 889
Query: 74 TLETPKEQGAEPIEATVV--HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
TP E EPI P P P + E +P P P+E TD
Sbjct: 890 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDT 949
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
S + + S+E ++ P P P+EP T+ P P
Sbjct: 950 PSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1009
Query: 192 EP---------PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGE 242
P P P ++ EP S+ P PE P+ P D E +
Sbjct: 1010 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSD 1068
Query: 243 NLTPTDE-NELDRRNRREELVALVTSDEKIVN--PRDHLVPLKSIPGFVLEQQTQPGPVI 299
TP+DE D +E T +E I P D P +P P
Sbjct: 1069 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTP-----------SDEPTPSD 1117
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDR 359
P+ T P E+ I P ++ P
Sbjct: 1118 EPTPSDEPTPSDEPT-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPS 1159
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEG 419
+EP + P S ++ IP+D+ PT + TP E
Sbjct: 1160 DEPTPSDEPTPSDEPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEP 1205
Query: 420 GKSNEH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH----SEGKMSNA 473
S+E + +PT + + P + PS +PT P+D+P P D TP S+ +
Sbjct: 1206 TPSDEPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPSDEPTPSDEPTPSE 1264
Query: 474 QRNNVLLSEGVKSNEQPTETPV---QKSVNPIKAPSIDPTLPTDQPVPIDLATPKHS 527
+ ++ P++ P + + + PS +PT P+D+P P D TP +
Sbjct: 1265 TPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTPSET 1320
Score = 76.3 bits (186), Expect = 2e-12
Identities = 117/527 (22%), Positives = 170/527 (32%), Gaps = 69/527 (13%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP--------EPVVVATAIPI 73
EP PS E + + EE I + P EP P
Sbjct: 787 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 846
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
TP E EPI P P + E +P P EP + +
Sbjct: 847 DEPTPSETPEEPIPTDT----PSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPI 902
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEP 193
PT S + + S+E ++ P P P+EP T+ P P P
Sbjct: 903 PTDTPSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETPEEPIPTDTPSDEPTP 956
Query: 194 ---------PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENL 244
P P ++ EP S+ P PE P+ P D E +
Sbjct: 957 SDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEP 1015
Query: 245 TPTDE-NELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCP 303
TP+DE D +E SDE P D P +T P+ P
Sbjct: 1016 TPSDEPTPSDEPTPSDEPTP---SDEP--TPSDEPTP----------SETPEEPIPTDTP 1060
Query: 304 NSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPN 363
+ T T S +P ++ P +EP
Sbjct: 1061 SDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPT 1120
Query: 364 KCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSN 423
+ P S ++ IP+D+ PT + TP E S+
Sbjct: 1121 PSDEPTPSDEPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEPTPSD 1166
Query: 424 EH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLS 481
E + +PT + + P + PS +PT P+D+P P D TP E S+ +
Sbjct: 1167 EPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPS-DEPTPSDEPTPSETPE 1224
Query: 482 EGVKSNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATPKHS 527
E + PT+TP + + PS +PT P+D+P P D TP +
Sbjct: 1225 EPI-----PTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTPSET 1265
Score = 64.3 bits (155), Expect = 9e-09
Identities = 108/506 (21%), Positives = 157/506 (30%), Gaps = 52/506 (10%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP----EPVVVATAIPI 73
E P P+P + E+ + +E S E P EP P
Sbjct: 928 EPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPS 987
Query: 74 TLETPKEQGAEPIEATVV--HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
TP E EPI P P P + E +P P EP +
Sbjct: 988 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 1047
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
SE + + S+E ++ P P P+EP T+ P P
Sbjct: 1048 SETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1107
Query: 192 EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-N 250
P P ++ EP S+ P PE P+ P D E + TP+DE
Sbjct: 1108 TPS---DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPT 1163
Query: 251 ELDRRNRREELVALVTSDEKIVN--PRDHLVPL-KSIPGFVLEQQTQPGPVIPVCPNSAS 307
D +E T +E I P D P + P +P P P+
Sbjct: 1164 PSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETP 1223
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPP-ETKKRVLDREEPNKCN 366
+ IP + + + P + P ET + + + P+
Sbjct: 1224 ----EEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1279
Query: 367 AKLPETLMLASNCHIDQAIPSDS-NPA-VPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNE 424
E D+ PSD P+ PT + TP + + + E S+E
Sbjct: 1280 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDE 1339
Query: 425 HNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGV 484
TP + PS +PT P+D+P P D TP
Sbjct: 1340 PTPSDEPTPSDEPT-----PSDEPT-PSDEPTPSDEPTPS-------------------- 1373
Query: 485 KSNEQPTETPVQKSVNPIKAPSIDPT 510
++ E+PT T P PS PT
Sbjct: 1374 ETPEEPTPT-----TTPTPTPSTTPT 1394
Score = 58.9 bits (141), Expect = 4e-07
Identities = 95/452 (21%), Positives = 131/452 (28%), Gaps = 51/452 (11%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQ 81
EP PS E + + EE I + P + P + P
Sbjct: 1026 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1085
Query: 82 GAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP----EPKETSNTDHSEPTQL 137
T P+P P+ + EP P EP EP + + PT
Sbjct: 1086 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDT 1145
Query: 138 CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGL 197
S + + S+E ++ P P P+EP T+ P P P
Sbjct: 1146 PSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPS--- 1196
Query: 198 AIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-NELDRRN 256
P ++ EP S+ P PE P+ P D E + TP+DE D
Sbjct: 1197 DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPTPSDEPT 1255
Query: 257 RREELVALVTSDEKIV--NPRDHLVPL-KSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQ 313
+E T +E I P D P + P +P P P+
Sbjct: 1256 PSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEP 1315
Query: 314 TIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETL 373
T P E+ I P ++ P +EP + P
Sbjct: 1316 T-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDE 1357
Query: 374 MLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNG------ 427
S D+ PSD P PE TP GG G
Sbjct: 1358 PTPS----DEPTPSD-EPTPSETPEEPTPTTTPTPTPSTTPTSGSGGSGGSGGGGGGGGG 1412
Query: 428 ----QPTETPVQKSVSPINAPSIDPTLPTDQP 455
PT TP K S I+ P+D P
Sbjct: 1413 TVPTSPTPTPTSKPTSTPAPTEIEEPTPSDVP 1444
>UniRef100_Q95YM2 I-connectin [Procambarus clarkii]
Length = 17352
Score = 78.2 bits (191), Expect = 6e-13
Identities = 124/566 (21%), Positives = 212/566 (36%), Gaps = 103/566 (18%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI--PITLE 76
E P+PL ++E+ KK+R K +K +EE + L P+ + P E
Sbjct: 7531 EAPKPLEEKPSEEEEPKLKKERPKPEKKEEEPEVPSWRGKRLPPKEEEKEEIVLKPFKKE 7590
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKK--KKKETVLEPQPEPEPEPKETSNT----- 129
P+E P P +P K + + + ++T LEP +P+ E T
Sbjct: 7591 KPEEP----------KPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTEPVKP 7640
Query: 130 -DHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLP-------------- 174
D +P +K KK+R + +E V E P+ +G LP
Sbjct: 7641 EDEEKPKPEEEIKPKKERIKPDKDEEV--------ETPSWRGKRLPPKEEDKEEITLKPF 7692
Query: 175 -EPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIP 233
+ KPKEP + P++ P P IP +PEK E + P P+P
Sbjct: 7693 KKEKPKEPKPS--PKIKPGKPYEPVIP-EPEKPPLEPYEKPEREKVPDQVPKP------- 7742
Query: 234 IDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQT 293
EK K P E E+ + REE EKI R P+ P +E++
Sbjct: 7743 ---EKEKVPEQVPEPEKEISPKPEREEKPQ---QPEKIPGKRKKRPPMLPAP---IEEKF 7793
Query: 294 QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK 353
+ + + + T+ ++ E + + KR+ + P ++ T PE
Sbjct: 7794 EIPKITLKKTTQNVFVPEEVTLETIELEH-VETPEVIEPEVEKRVWTPPPEYETYVPE-- 7850
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK- 412
E P K E ++L + P P + E + K++++ K K
Sbjct: 7851 ------EIPEK------EPVVL-------EKYEKYEPPTKPKDEEEEDKGKYERKPKDKP 7891
Query: 413 ------NVLLSEGGKSNEHNGQPTET--PVQKSVSP---INAPSIDPTLPTDQPVPIDLA 461
+ L +G E G+ + P ++ SP P + P +P +P +
Sbjct: 7892 EPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP-IPKKKPEEEEKV 7950
Query: 462 TPKHSEGKMSNAQ---RNNVLLSEGVKSNEQ---PTETPVQKSVNPIKAPSIDPTLPTDQ 515
GK + + R V L ++ + + P++K + P P P++ +
Sbjct: 7951 KVTPKPGKKPSKEIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSMEPEV 8010
Query: 516 PVPIDLATPKHSEGKMSKAQRRKKNK 541
P P++ PK E K K ++R + K
Sbjct: 8011 PKPVEEKPPKEEEPKPKKVRKRPEKK 8036
Score = 74.7 bits (182), Expect = 7e-12
Identities = 127/570 (22%), Positives = 213/570 (37%), Gaps = 111/570 (19%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI--PITLE 76
E P+PL ++E+ KK+R K +K +EE + L P+ + P E
Sbjct: 6575 EAPKPLEEKPSEEEEPKLKKERPKPEKKEEEAEVPSWRGKRLPPKEEEKEEIVLKPFKKE 6634
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKK--KKKETVLEPQPEPEPEPKETSNT----- 129
P+E P P +P K + + + ++T LEP +P+ E T
Sbjct: 6635 KPEEP----------KPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTEPVKP 6684
Query: 130 -DHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLP-------------- 174
D +P +K KK+R + +E V E P+ +G LP
Sbjct: 6685 EDEEKPKPEEEIKPKKERIKPDKDEEV--------ETPSWRGKRLPPKEEDKEEITLKPF 6736
Query: 175 -EPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIP 233
+ KPKEP + P++ P P IP +PEK E + P P+P
Sbjct: 6737 KKEKPKEPKPS--PKIKPGKPYEPVIP-EPEKPPLEPYEKPEREKVPDQVPKP------- 6786
Query: 234 IDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQT 293
EK K P E E+ + REE + EKI R P+ + P +E++
Sbjct: 6787 ---EKEKVPEQVPEPEKEISPKPEREEKPQQL---EKIPGKRRKRPPMLAAP---IEEKF 6837
Query: 294 QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK 353
+ + + + T+ ++ E + + KR+ S P ++ T PE
Sbjct: 6838 EIPKITLKKTTQNVFVPEEVTLETIELEH-VETPEVIEPEVEKRVWSPPPEYETYVPE-- 6894
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK- 412
E P K +L + P P + E + K++++ K K
Sbjct: 6895 ------EIPEKEPVEL-------------EKYEKYEPPTKPKDEEEEDKGKYERKPKDKP 6935
Query: 413 ------NVLLSEGGKSNEHNGQPTET--PVQKSVSP---INAPSIDPTLPTDQPVPI--D 459
+ L +G E G+ + P ++ SP P + P +P +P D
Sbjct: 6936 EPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP-IPKKKPEEEKKD 6994
Query: 460 LATPKHSEGKMSNA-QRNNVLLS-------EGVKSNEQPTETPVQKSVNPIKAPSIDPTL 511
TPK + R V L E + ++ P E P++ P + PSI+P
Sbjct: 6995 KVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSIEP-- 7052
Query: 512 PTDQPVPIDLATPKHSEGKMSKAQRRKKNK 541
+ P P++ + E K+ K + + + K
Sbjct: 7053 --EAPKPLEEKPSEEEEPKLKKERPKPEKK 7080
Score = 73.9 bits (180), Expect = 1e-11
Identities = 128/570 (22%), Positives = 215/570 (37%), Gaps = 111/570 (19%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI--PITLE 76
E P+PL ++E+ KK+R K +K +EE + L P+ + P E
Sbjct: 7053 EAPKPLEEKPSEEEEPKLKKERPKPEKKEEEPEVPSWRGKRLPPKEEEKEEIVLKPFKKE 7112
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKK--KKKETVLEPQPEPEPEPKETSNT----- 129
P+E P P +P K + + + ++T LEP +P+ E T
Sbjct: 7113 KPEEP----------KPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTEPVKP 7162
Query: 130 -DHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLP-------------- 174
D +P +K KK+R + +E V E P+ +G LP
Sbjct: 7163 EDEEKPQPEEEIKPKKERIKPDKDEEV--------ETPSWRGKRLPPKEEDKEEITLKPF 7214
Query: 175 -EPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIP 233
+ KPKEP + P++ P P IP +PEK E + P P+P
Sbjct: 7215 KKEKPKEPKPS--PKIKPGKPYEPVIP-EPEKPPLEPYEKPEREKVPDQVPKP------- 7264
Query: 234 IDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQT 293
EK K P E E+ + REE + EKI R P+ + P +E++
Sbjct: 7265 ---EKEKVPEQVPEPEKEISPKPEREEKPQQL---EKIPGKRRKRPPMLAAP---IEEKF 7315
Query: 294 QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK 353
+ + + + T+ ++ E + + KR+ S P ++ T PE
Sbjct: 7316 EIPKITLKKTTQNVFVPEEVTLETIELEH-VETPEVIEPEVEKRVWSPPPEYETYVPE-- 7372
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK- 412
E P K E ++L + P P + E + K++++ K K
Sbjct: 7373 ------EIPEK------EPVVL-------EKYEKYEPPTKPKDEEEEDKGKYERKPKDKP 7413
Query: 413 ------NVLLSEGGKSNEHNGQPTET--PVQKSVSP---INAPSIDPTLPTDQPVPI--D 459
+ L +G E G+ + P ++ SP P + P +P +P D
Sbjct: 7414 EPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP-IPKKKPEEEEKD 7472
Query: 460 LATPKHSEGKMSNA-QRNNVLLS-------EGVKSNEQPTETPVQKSVNPIKAPSIDPTL 511
TPK + R V L E + ++ P E P++ P + PSI+P
Sbjct: 7473 KVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSIEP-- 7530
Query: 512 PTDQPVPIDLATPKHSEGKMSKAQRRKKNK 541
+ P P++ + E K+ K + + + K
Sbjct: 7531 --EAPKPLEEKPSEEEEPKLKKERPKPEKK 7558
Score = 63.9 bits (154), Expect = 1e-08
Identities = 81/339 (23%), Positives = 133/339 (38%), Gaps = 31/339 (9%)
Query: 14 KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPI 73
K + E KP+ P PE+D++ K K R +++ +E+ ++ + + PI
Sbjct: 7880 KGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKPI 7939
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
+ P+E+ E V P P ++P+K ++ E LEP EPE + +
Sbjct: 7940 PKKKPEEE-----EKVKVTPKPGKKPSKEIPDREPVE--LEPFERTEPEILDKDKVPLEK 7992
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEP--CSTEHPRVCP 191
P + K+K E + V E EP + PE K +EP S R+ P
Sbjct: 7993 PLKPKPEPKEKPSMEPEVPKPVEEKPPKEEEPKPKKVRKRPEKKDEEPEVPSWRGRRLPP 8052
Query: 192 EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENE 251
+ I + P K K AEP P+ P P IP +PEK L P + E
Sbjct: 8053 KEEEKEEIVLKPFKKEKPAEPKPK----PKRTPGKPYEPEIP-EPEK---PPLEPYSKPE 8104
Query: 252 LDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQ 311
++ + EE++ + K + + PL +P E P A +
Sbjct: 8105 KEKSPKPEEVLKKPSKKPKKIKEAEPKKPL--VPVMATE-----------VPEEAKVEET 8151
Query: 312 SQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPP 350
T ++ + + K+ + K KR+N P PP
Sbjct: 8152 KATRVDIELTEVVTKKESVVK-SVKRVNQKPKDIEVIPP 8189
Score = 60.5 bits (145), Expect = 1e-07
Identities = 135/575 (23%), Positives = 217/575 (37%), Gaps = 82/575 (14%)
Query: 6 QSELLHSKKRRREEKPEP----------LPSPEQDQEQSCSK--KKRRKKKKIKEEGIES 53
+ E+ K+R + +K E LP E+D+E+ K KK + K+ I+
Sbjct: 7649 EEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEEDKEEITLKPFKKEKPKEPKPSPKIKP 7708
Query: 54 HEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVL 113
+ + ++PEP ++ EP E VPDQ P K +KE V
Sbjct: 7709 GKPYEPVIPEP--------------EKPPLEPYEKPEREKVPDQVP------KPEKEKVP 7748
Query: 114 EPQPEPEPE--PKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGG 171
E PEPE E PK +P ++ +KK+ E E+ + T Q
Sbjct: 7749 EQVPEPEKEISPKPEREEKPQQPEKIPGKRKKRPPMLPAPIEEKFEIPKI-TLKKTTQNV 7807
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPE-KNRKEAEPNESNAEHPRACPEPPLGL 230
+PE E EH PE I+PE + R P E P PE
Sbjct: 7808 FVPEEVTLETIELEHVET-PEV-------IEPEVEKRVWTPPPEYETYVPEEIPEKE--- 7856
Query: 231 AIPIDPEK-NKGENLT-PTDENELDRRN--RREELVALVTSDEKIVNPRDHLVPLKSIPG 286
P+ EK K E T P DE E D+ R+ + D K+ + L P +
Sbjct: 7857 --PVVLEKYEKYEPPTKPKDEEEEDKGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGE- 7913
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH- 345
E++ +P P P + Q + IP E++ K K +K +PD+
Sbjct: 7914 ---EKKLKPPKRRPKSPEKEAEKPQLKPIPKKKPEEE-EKVKVTPKPGKKPSKEIPDREP 7969
Query: 346 -NTEPPE-TKKRVLDREEP--NKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKT 401
EP E T+ +LD+++ K PE S ++ +P P E K
Sbjct: 7970 VELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPS---MEPEVPKPVEEKPPKEEEPK- 8025
Query: 402 PKKWKKRAKKKN---VLLSEGGKSNEHNGQPTETPV------QKSVSPINAPSIDPTLPT 452
PKK +KR +KK+ + S G+ + E V +K P P P P
Sbjct: 8026 PKKVRKRPEKKDEEPEVPSWRGRRLPPKEEEKEEIVLKPFKKEKPAEPKPKPKRTPGKPY 8085
Query: 453 DQPVPIDLATP--KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPT 510
+ +P P +S+ + + + +L + K ++ E +K + P+ A +
Sbjct: 8086 EPEIPEPEKPPLEPYSKPEKEKSPKPEEVLKKPSKKPKKIKEAEPKKPLVPVMATEVPEE 8145
Query: 511 LPTDQP----VPIDLATPKHSEGKMSKAQRRKKNK 541
++ V I+L + + K+ +R K
Sbjct: 8146 AKVEETKATRVDIELTEVVTKKESVVKSVKRVNQK 8180
Score = 56.6 bits (135), Expect = 2e-06
Identities = 119/537 (22%), Positives = 202/537 (37%), Gaps = 73/537 (13%)
Query: 6 QSELLHSKKRRREEKPEP----------LPSPEQDQEQSCSK--KKRRKKKKIKEEGIES 53
+ E+ K+R + +K E LP E+D+E+ K KK + K+ I+
Sbjct: 6693 EEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEEDKEEITLKPFKKEKPKEPKPSPKIKP 6752
Query: 54 HEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVL 113
+ + ++PEP ++ EP E VPDQ P K+K E V
Sbjct: 6753 GKPYEPVIPEP--------------EKPPLEPYEKPEREKVPDQVPKP--EKEKVPEQVP 6796
Query: 114 EPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATV--CTEPPAVQGG 171
EP+ E P+P+ +P QL + K++++ + E + T Q
Sbjct: 6797 EPEKEISPKPER-----EEKPQQLEKIPGKRRKRPPMLAAPIEEKFEIPKITLKKTTQNV 6851
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPE-KNRKEAEPNESNAEHPRACPEPPLGL 230
+PE E EH PE I+PE + R + P E P PE
Sbjct: 6852 FVPEEVTLETIELEHVET-PE-------VIEPEVEKRVWSPPPEYETYVPEEIPEKE--- 6900
Query: 231 AIPIDPEK-NKGENLT-PTDENELD--RRNRREELVALVTSDEKIVNPRDHLVPLKSIPG 286
P++ EK K E T P DE E D + R+ + D K+ + L P +
Sbjct: 6901 --PVELEKYEKYEPPTKPKDEEEEDKGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGE- 6957
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH- 345
E++ +P P P + Q + IP E++ K K +K +PD+
Sbjct: 6958 ---EKKLKPPKRRPKSPEKEAEKPQLKPIPKKKPEEE-KKDKVTPKPGKKPSKKIPDREP 7013
Query: 346 -NTEPPE-TKKRVLDREE-PNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTP 402
EP E T+ +LD+++ P + K + + P + P+ P+ K
Sbjct: 7014 VELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSIEPEAPKPLEEKPSEEEEPKLKKE 7073
Query: 403 KKWKKRAKKKNVLLSEGGKSNEHNGQPTETPV------QKSVSPINAPSIDPTLPTDQPV 456
+ ++ +++ + S GK + E V +K P P P P + +
Sbjct: 7074 RPKPEKKEEEPEVPSWRGKRLPPKEEEKEEIVLKPFKKEKPEEPKPKPKYKPGKPYEPEI 7133
Query: 457 PIDLATP-----KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSID 508
P TP K + K+ + V + K + P ++ + P K ++
Sbjct: 7134 PEPEKTPLEPYTKPDKEKVPDGVTEPVKPEDEEKPQPEEEIKPKKERIKPDKDEEVE 7190
Score = 55.8 bits (133), Expect = 3e-06
Identities = 118/581 (20%), Positives = 209/581 (35%), Gaps = 103/581 (17%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
+++ E P+P E+ +E+ K K+ + K KEE E ++ P +P
Sbjct: 6089 REKPSTEPGRPIPWEEKLEEEGKPKPKKERTKPEKEE-----EESEL----PSWRGRRLP 6139
Query: 73 ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHS 132
PKE+ E ++ P ++P T K K K P PEP++T +
Sbjct: 6140 -----PKEEEKEDVQLK-----PFEKPKPTKPKPKPKHKPGTPYEPEIPEPEKTPLEPYD 6189
Query: 133 EPTQLCSVKKKKKRKGAESNE-------------AVAELATVCTEPPAVQGGVLPEP--- 176
+P + + + E E AV E P+ +G LP
Sbjct: 6190 KPKMQITPDHEPQPVEDEDEEKLPSDEQPKLKKKAVKPKKDEEEEIPSWRGKRLPPKEDE 6249
Query: 177 ------KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGL 230
KP + + P+ P P L P +PE E P E P + PE +
Sbjct: 6250 KEEITLKPFKKVKPKEPK--PSPKLKPGKPYEPEIPEPEKSPLE-----PYSKPEKEVSD 6302
Query: 231 AIP---IDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGF 287
IP + + E P + +LD +++ + +T P+ L LK+
Sbjct: 6303 KIPELAKEVSRKPEEPEKPEEPEKLDESDKKPDESETITQ-----KPKRRLQKLKA---- 6353
Query: 288 VLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNT 347
E++ + V + + + T+ V+ E + + KR+ S P ++ T
Sbjct: 6354 PTEEKFEIPKVTLRKTSQKVFVPEEVTLETVELEH-VETPEVVEPEVEKRVWSPPPEYET 6412
Query: 348 EPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKK 407
PE E P K +L + P P + E + K+++
Sbjct: 6413 YVPE--------EIPEKEPVEL-------------EKYEKYEPPTKPKDEEEEDKGKYER 6451
Query: 408 RAKKK-------NVLLSEGGKSNEHNGQ--PTETPVQKSVSP---INAPSIDPTLPTDQP 455
+ K K + L +G E G+ + P ++ SP P + P +P +P
Sbjct: 6452 KPKDKPEPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP-IPKKKP 6510
Query: 456 --VPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNE----QPTETPVQKSVNPIKAPSIDP 509
D TPK + + E + E + P++K + P P P
Sbjct: 6511 EEEKKDKVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKP 6570
Query: 510 TLPTDQPVPIDLATPKHSEGKMSKAQRR--KKNKRALKSAW 548
++ + P P++ + E K+ K + + KK + A +W
Sbjct: 6571 SIEPEAPKPLEEKPSEEEEPKLKKERPKPEKKEEEAEVPSW 6611
Score = 55.5 bits (132), Expect = 4e-06
Identities = 135/597 (22%), Positives = 228/597 (37%), Gaps = 113/597 (18%)
Query: 17 REEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGI-ESHEHDQVLLPEPVVVATAIPITL 75
R+E+ +P E+ + S K+ K+++KEE I + D+ P+P
Sbjct: 5749 RKERTKPDRKEEEKESPSWKIKRIPPKEEVKEEIILKPFTKDKPEEPKPA---------- 5798
Query: 76 ETPKEQGAEPIEATVVHPVPDQRPAKTHRK-KKKKETVLEPQPEPEPEPKETSNTD---- 130
PK +P E V P P++ P + +RK K+K + LE Q + E + + TD
Sbjct: 5799 RRPKP--GKPYEPEV--PEPEKTPLEPYRKTDKEKVSELERQRDLEDLKVDETVTDIRED 5854
Query: 131 ----HSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEH 186
H + Q K+ +K K + ++ ++A T P +PE + E EH
Sbjct: 5855 ELPVHPDKVQAKPGKRPQKEKPQKEEFSIPKVALKKTVPKK----FVPEEEKLESVDLEH 5910
Query: 187 PRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEH-PRACPE-PPLGLAIP--IDP-EKNKG 241
+P +P K ++E P + P PE P+ L P +P E+ K
Sbjct: 5911 VEKPKKP--------EPTKEKREWSPMPDYETYAPDELPEREPVELEKPDTFEPTERTKD 5962
Query: 242 ENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVI 299
E E E D+ R+ + ++K+ + P + E+Q +PG +
Sbjct: 5963 EK-----EQEKDKYQRKPKEKTEYGEEKKLKLGKGRWPPEEE------EEQIKLKPGKRL 6011
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH--NTEPPE-TKKRV 356
P P + IP E + ++ + KR +P++ EP E +
Sbjct: 6012 PWQPEEEKEAPHLKPIPRRKPETEDKEKVPLKPGKRP-SKDIPEREPVELEPFERVDSDI 6070
Query: 357 LDR-----EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKK 411
LD+ EEP K KL E PS + P P E K ++ K + KK
Sbjct: 6071 LDKDKVQLEEPVKPEPKLREK-------------PS-TEPGRPIPWEEKLEEEGKPKPKK 6116
Query: 412 KNVLLSEGGKSNEHNGQPT-----ETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHS 466
+ ++ K E + P+ P ++ + + PT +P P PKH
Sbjct: 6117 ER---TKPEKEEEESELPSWRGRRLPPKEEEKEDVQLKPFEKPKPT-KPKP----KPKHK 6168
Query: 467 EGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKH 526
G + +P +TP++ P P + T P +P P++
Sbjct: 6169 PGTPYEPE------------IPEPEKTPLE----PYDKPKMQIT-PDHEPQPVE----DE 6207
Query: 527 SEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQ--RTESLKLVEAKSVKAK 581
E K+ ++ K K+A+K E S + + P + E + L K VK K
Sbjct: 6208 DEEKLPSDEQPKLKKKAVKPKKDEEEEIPSWRGKRLPPKEDEKEEITLKPFKKVKPK 6264
Score = 55.1 bits (131), Expect = 6e-06
Identities = 89/396 (22%), Positives = 152/396 (37%), Gaps = 45/396 (11%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEE-GIESHEHDQVLLPEP 64
+SE + K +RR +K + P+ E+ + + +K +K + EE +E+ E + V PE
Sbjct: 6336 ESETITQKPKRRLQKLKA-PTEEKFEIPKVTLRKTSQKVFVPEEVTLETVELEHVETPEV 6394
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPVPDQR------PAKTHRKKKKKETVLEPQPE 118
V + P+ + P E PV ++ P K ++++ + E +P+
Sbjct: 6395 VEPEVEKRVWSPPPEYETYVPEEIPEKEPVELEKYEKYEPPTKPKDEEEEDKGKYERKPK 6454
Query: 119 PEPEPKETSNTDHSE----PTQLCSVKK----KKKRKGAESNEAVAELATVCTEPPAVQ- 169
+PEP+E + P + KK K++ K E +L + + P +
Sbjct: 6455 DKPEPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKPIPKKKPEEEK 6514
Query: 170 -GGVLPEPKPK-------------EPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNES 215
V P+P K EP P + + + L P+ P+ KE E
Sbjct: 6515 KDKVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSIEP 6574
Query: 216 NA-----EHPRACPEPPLGLAIPIDPEKNKGENLTPTDENEL--DRRNRREELVALVTSD 268
A E P EP L P PEK + E P+ + + +EE+V
Sbjct: 6575 EAPKPLEEKPSEEEEPKLKKERP-KPEKKEEEAEVPSWRGKRLPPKEEEKEEIVLKPFKK 6633
Query: 269 EKIVNPRDHLVPLKSIPGFVLE---QQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKIN 325
EK P + K PG E + + P+ P + T PV +++
Sbjct: 6634 EK---PEEPKPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTEPVKPEDEEKP 6690
Query: 326 KRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREE 361
K K K++R+ D+ P KR+ +EE
Sbjct: 6691 KPEEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEE 6726
Score = 54.7 bits (130), Expect = 7e-06
Identities = 119/537 (22%), Positives = 201/537 (37%), Gaps = 73/537 (13%)
Query: 6 QSELLHSKKRRREEKPEP----------LPSPEQDQEQSCSK--KKRRKKKKIKEEGIES 53
+ E+ K+R + +K E LP E+D+E+ K KK + K+ I+
Sbjct: 7171 EEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEEDKEEITLKPFKKEKPKEPKPSPKIKP 7230
Query: 54 HEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVL 113
+ + ++PEP ++ EP E VPDQ P K+K E V
Sbjct: 7231 GKPYEPVIPEP--------------EKPPLEPYEKPEREKVPDQVPKP--EKEKVPEQVP 7274
Query: 114 EPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATV--CTEPPAVQGG 171
EP+ E P+P+ +P QL + K++++ + E + T Q
Sbjct: 7275 EPEKEISPKPER-----EEKPQQLEKIPGKRRKRPPMLAAPIEEKFEIPKITLKKTTQNV 7329
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPE-KNRKEAEPNESNAEHPRACPEPPLGL 230
+PE E EH PE I+PE + R + P E P PE
Sbjct: 7330 FVPEEVTLETIELEHVET-PE-------VIEPEVEKRVWSPPPEYETYVPEEIPEKE--- 7378
Query: 231 AIPIDPEK-NKGENLT-PTDENELD--RRNRREELVALVTSDEKIVNPRDHLVPLKSIPG 286
P+ EK K E T P DE E D + R+ + D K+ + L P +
Sbjct: 7379 --PVVLEKYEKYEPPTKPKDEEEEDKGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGE- 7435
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH- 345
E++ +P P P + Q + IP E++ K K +K +PD+
Sbjct: 7436 ---EKKLKPPKRRPKSPEKEAEKPQLKPIPKKKPEEE-EKDKVTPKPGKKPSKKIPDREP 7491
Query: 346 -NTEPPE-TKKRVLDREE-PNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTP 402
EP E T+ +LD+++ P + K + + P + P+ P+ K
Sbjct: 7492 VELEPFERTEPEILDKDKVPLEKPLKPKPEPKEKPSIEPEAPKPLEEKPSEEEEPKLKKE 7551
Query: 403 KKWKKRAKKKNVLLSEGGKSNEHNGQPTETPV------QKSVSPINAPSIDPTLPTDQPV 456
+ ++ +++ + S GK + E V +K P P P P + +
Sbjct: 7552 RPKPEKKEEEPEVPSWRGKRLPPKEEEKEEIVLKPFKKEKPEEPKPKPKYKPGKPYEPEI 7611
Query: 457 PIDLATP-----KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSID 508
P TP K + K+ + V + K + P ++ + P K ++
Sbjct: 7612 PEPEKTPLEPYTKPDKEKVPDGVTEPVKPEDEEKPKPEEEIKPKKERIKPDKDEEVE 7668
Score = 52.4 bits (124), Expect = 4e-05
Identities = 79/330 (23%), Positives = 125/330 (36%), Gaps = 46/330 (13%)
Query: 8 ELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHE--HDQVLLPEPV 65
E+ K + + K +P P E+ E+ KK ++KI EE E + PEP
Sbjct: 14914 EVTEEVKIKMKPKKKPEPKIEEVTEEVTIKKP---EEKIDEEITEEVQIKRKPKKKPEPK 14970
Query: 66 VVATAIPITLETPKEQGAEPIEATVVHPVPDQR-PAKTHRK---KKKKETVLEPQPE--- 118
+ +T++ PKE+ E I VV P+++ P + + KK +E V+E E
Sbjct: 14971 IEEVTEEVTIKKPKEKVVEEITEEVVIKKPEEKVPEEVSEEVTIKKPEEKVVEEVTEEVK 15030
Query: 119 ------PEPEPKETSNTDH-----------SEPTQLCSVKKKKKRKGAESNEAVAELATV 161
+PEPK T+ E T+ +K+K K+K E V E T+
Sbjct: 15031 IKMKLKKKPEPKIEEVTEEVTIKKPEEKIDEEITEEVQIKRKPKKKPEPKIEEVTEEVTL 15090
Query: 162 CTEPPAVQGGVLPE---PKPKEPCSTEHPRVCPEPPLGLAIPIDPE--------KNRKEA 210
+ E KP+E V + P + + E K + E
Sbjct: 15091 RKPKEEAIEEITEEVTIKKPEEKIEEVSEEVTIKKPEEKVVEVVTEEVKIKMKPKKKPEF 15150
Query: 211 EPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRRE------ELVAL 264
+ E + E PE + + I K K T E+ + +E E V L
Sbjct: 15151 KVEEVSEEITIKKPEEEVAEEVQIRKPKKKSVFKTEEISEEITLQKPKEKVEEVTEEVTL 15210
Query: 265 VTSDEKIVNPRDHLVPLKSIPGFVLEQQTQ 294
+EKIV V +K V+E+ T+
Sbjct: 15211 KRPEEKIVEEVSEEVTIKKPDEKVVEEVTE 15240
Score = 51.2 bits (121), Expect = 8e-05
Identities = 115/517 (22%), Positives = 176/517 (33%), Gaps = 76/517 (14%)
Query: 12 SKKRRREEKPEPL----------------PSPEQDQEQSCSKKKRRKKKKIKEE-GIESH 54
S K REEKP+ L P E+ + + KK + + EE +E+
Sbjct: 7281 SPKPEREEKPQQLEKIPGKRRKRPPMLAAPIEEKFEIPKITLKKTTQNVFVPEEVTLETI 7340
Query: 55 EHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPV---------PDQRPAKTHRK 105
E + V PE + + P+ + P E PV P +P +
Sbjct: 7341 ELEHVETPEVIEPEVEKRVWSPPPEYETYVPEEIPEKEPVVLEKYEKYEPPTKPKDEEEE 7400
Query: 106 KK-KKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKK----KKKRKGAESNEAVAELAT 160
K K E + +PEPE + K P + KK K++ K E +L
Sbjct: 7401 DKGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP 7460
Query: 161 VCTEPPAVQ--GGVLPEPKPK-------------EPCSTEHPRVCPEPPLGLAIPIDPEK 205
+ + P + V P+P K EP P + + + L P+ P+
Sbjct: 7461 IPKKKPEEEEKDKVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKP 7520
Query: 206 NRKEAEPNESNA-----EHPRACPEPPLGLAIPIDPEKNKGENLTPTDENEL--DRRNRR 258
KE E A E P EP L P PEK + E P+ + + +
Sbjct: 7521 EPKEKPSIEPEAPKPLEEKPSEEEEPKLKKERP-KPEKKEEEPEVPSWRGKRLPPKEEEK 7579
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLE---QQTQPGPVIPVCPNSASLIGQSQTI 315
EE+V EK P + K PG E + + P+ P + T
Sbjct: 7580 EEIVLKPFKKEK---PEEPKPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTE 7636
Query: 316 PVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEP---------NKCN 366
PV +++ K K K++R+ D+ P KR+ +EE K
Sbjct: 7637 PVKPEDEEKPKPEEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEEDKEEITLKPFKKEK 7696
Query: 367 AKLPE-TLMLASNCHIDQAIPSDSNPAVP--TNPE-HKTPKKWKKRAKKKNVLLSEGGKS 422
K P+ + + + IP P + PE K P + K K+K + E
Sbjct: 7697 PKEPKPSPKIKPGKPYEPVIPEPEKPPLEPYEKPEREKVPDQVPKPEKEK---VPEQVPE 7753
Query: 423 NEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPID 459
E P +K P P P P PI+
Sbjct: 7754 PEKEISPKPEREEKPQQPEKIPGKRKKRPPMLPAPIE 7790
Score = 50.1 bits (118), Expect = 2e-04
Identities = 68/350 (19%), Positives = 139/350 (39%), Gaps = 27/350 (7%)
Query: 8 ELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVV 67
E+ + +++ K P P E+ E+ KK K + E ++ + PEP +
Sbjct: 14732 EVTEEVQIKKKPKKTPEPKIEEVTEEVTLKKPEEKVVEEVTEEVKIKRKPKKK-PEPKIE 14790
Query: 68 ATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETS 127
+T++ P+E+ E + VV P++ K H + ++ T+ +P+ +
Sbjct: 14791 EVTEEVTIKKPEEKVIEEVTEEVVIKKPEE---KVHEEVSEEVTIKKPEEKIV------- 14840
Query: 128 NTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHP 187
E T+ +K+K K+K E V E T+ V V E ++P
Sbjct: 14841 ----EEVTEEVKIKRKPKKKPEPKIEEVTEEVTLKKPEEKVIEEVTEEVVIRKP----EE 14892
Query: 188 RVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIP----IDPEKNKGEN 243
+V E + I EK +E P+ PEP + PE+ E
Sbjct: 14893 KVVEEVSEEVTIKKPEEKVVEEVTEEVKIKMKPKKKPEPKIEEVTEEVTIKKPEEKIDEE 14952
Query: 244 LTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCP 303
+T + + + + E + VT + I P++ +V + I V+ + +P +P
Sbjct: 14953 ITEEVQIKRKPKKKPEPKIEEVTEEVTIKKPKEKVV--EEITEEVVIK--KPEEKVPEEV 15008
Query: 304 NSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK 353
+ I + + V + +++ + ++ K ++ + ++ + PE K
Sbjct: 15009 SEEVTIKKPEEKVVEEVTEEVKIKMKLKKKPEPKIEEVTEEVTIKKPEEK 15058
Score = 49.7 bits (117), Expect = 2e-04
Identities = 89/406 (21%), Positives = 148/406 (35%), Gaps = 60/406 (14%)
Query: 12 SKKRRREEKPEPL----------------PSPEQDQEQSCSKKKRRKKKKIKEE-GIESH 54
S K REEKP+ L P E+ + + KK + + EE +E+
Sbjct: 6803 SPKPEREEKPQQLEKIPGKRRKRPPMLAAPIEEKFEIPKITLKKTTQNVFVPEEVTLETI 6862
Query: 55 EHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQR------PAKTHRKKKK 108
E + V PE + + P+ + P E PV ++ P K ++++
Sbjct: 6863 ELEHVETPEVIEPEVEKRVWSPPPEYETYVPEEIPEKEPVELEKYEKYEPPTKPKDEEEE 6922
Query: 109 KETVLEPQPEPEPEPKETSNTDHSE----PTQLCSVKK----KKKRKGAESNEAVAELAT 160
+ E +P+ +PEP+E + P + KK K++ K E +L
Sbjct: 6923 DKGKYERKPKDKPEPEEDRKLKLGKGKLRPEEEGEEKKLKPPKRRPKSPEKEAEKPQLKP 6982
Query: 161 VCTEPPAVQ--GGVLPEPKPK-------------EPCSTEHPRVCPEPPLGLAIPIDPEK 205
+ + P + V P+P K EP P + + + L P+ P+
Sbjct: 6983 IPKKKPEEEKKDKVTPKPGKKPSKKIPDREPVELEPFERTEPEILDKDKVPLEKPLKPKP 7042
Query: 206 NRKEAEPNESNA-----EHPRACPEPPLGLAIPIDPEKNKGENLTPTDENEL--DRRNRR 258
KE E A E P EP L P PEK + E P+ + + +
Sbjct: 7043 EPKEKPSIEPEAPKPLEEKPSEEEEPKLKKERP-KPEKKEEEPEVPSWRGKRLPPKEEEK 7101
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLE---QQTQPGPVIPVCPNSASLIGQSQTI 315
EE+V EK P + K PG E + + P+ P + T
Sbjct: 7102 EEIVLKPFKKEK---PEEPKPKPKYKPGKPYEPEIPEPEKTPLEPYTKPDKEKVPDGVTE 7158
Query: 316 PVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREE 361
PV +++ + K K++R+ D+ P KR+ +EE
Sbjct: 7159 PVKPEDEEKPQPEEEIKPKKERIKPDKDEEVETPSWRGKRLPPKEE 7204
Score = 48.9 bits (115), Expect = 4e-04
Identities = 125/638 (19%), Positives = 228/638 (35%), Gaps = 85/638 (13%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETP 78
+KPE E +E + K + + +++ EE + + PEP + +TL+ P
Sbjct: 14816 KKPEEKVHEEVSEEVTIKKPEEKIVEEVTEEVKIKRKPKKK--PEPKIEEVTEEVTLKKP 14873
Query: 79 KEQGAEPIEATVVHPVPDQRPAK------THRKKKKK-------ETVLEPQPEPEPEPKE 125
+E+ E + VV P+++ + T +K ++K E ++ +P+ +PEPK
Sbjct: 14874 EEKVIEEVTEEVVIRKPEEKVVEEVSEEVTIKKPEEKVVEEVTEEVKIKMKPKKKPEPKI 14933
Query: 126 TSNTDH-----------SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAV-----Q 169
T+ E T+ +K+K K+K E V E T+ V +
Sbjct: 14934 EEVTEEVTIKKPEEKIDEEITEEVQIKRKPKKKPEPKIEEVTEEVTIKKPKEKVVEEITE 14993
Query: 170 GGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPE-----KNRKEAEPNESNAEHPRACP 224
V+ +P+ K P +P + + E K +K+ EP
Sbjct: 14994 EVVIKKPEEKVPEEVSEEVTIKKPEEKVVEEVTEEVKIKMKLKKKPEPKIEEVTEEVTIK 15053
Query: 225 EPPLGLAIPIDPE-------KNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDH 277
+P + I E K K E E+ R +EE + +T + I P +
Sbjct: 15054 KPEEKIDEEITEEVQIKRKPKKKPEPKIEEVTEEVTLRKPKEEAIEEITEEVTIKKPEEK 15113
Query: 278 L------VPLKSIPGFVLEQQTQPGPV--IPVCPNSASLIGQSQTIPVVDTEQKINKRSR 329
+ V +K V+E T+ + P + S+ I + E+++ + +
Sbjct: 15114 IEEVSEEVTIKKPEEKVVEVVTEEVKIKMKPKKKPEFKVEEVSEEITIKKPEEEVAEEVQ 15173
Query: 330 MSKMKRK---RMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIP 386
+ K K+K + + ++ + P+ K E + K PE + + I
Sbjct: 15174 IRKPKKKSVFKTEEISEEITLQKPKEKV----EEVTEEVTLKRPEE-KIVEEVSEEVTIK 15228
Query: 387 SDSNPAVPTNPEH---KTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINA 443
V E K K K + + + V K E + V+ + P
Sbjct: 15229 KPDEKVVEEVTEEVQIKMKPKMKPKYEVEEVTEEMTIKQPEEEVEEITEEVRFKLKPKKK 15288
Query: 444 P-------SIDPTLPTDQPVPIDLAT--------PKHSEGKMSNAQRNNVLLSEGVKSNE 488
P S + T+ + ++ PK + + + +S+ ++ E
Sbjct: 15289 PEPKYEEVSSEVTIMRKREDKVEEVVEDVHIKMKPKEKPQEKFDDVSEEITISK-PETKE 15347
Query: 489 QPTE---TPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKA---QRRKKNKR 542
Q TE VQ + P K P I T++ I P E +S+ +R+ K K
Sbjct: 15348 QVTEEITEDVQIKLKPKKKPDIRTEEVTEEVTIIRKEEPSEEEEDISETVQIKRKPKRKI 15407
Query: 543 ALKSAWSESVHHSSDQNAKTPVQR-TESLKLVEAKSVK 579
K V + + PV+ TE L K K
Sbjct: 15408 TTKEEEVTEVTIQKPKPKEEPVEEVTEEFMLKRPKPKK 15445
Score = 48.1 bits (113), Expect = 7e-04
Identities = 58/252 (23%), Positives = 99/252 (39%), Gaps = 17/252 (6%)
Query: 41 RKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPA 100
+ K + E + + D ++L P I + E+ +E E E V +Q
Sbjct: 14448 KAKVTVTENLQRADQEDVIVLRGPTKEKKIIEVVEESDEELVKEIPEVKEEEIVEEQFKL 14507
Query: 101 KTHRKKKKKETVLEPQPEPEPEPKE------TSNTDHSEPTQLCSVKKKKKRKGAESNEA 154
K KKK KE + E +PE KE D E T+ +KKK K+K + E
Sbjct: 14508 KPKTKKKVKEEITEEVIIKKPEEKEEVIEEVIKKPDEIEVTEEVMIKKKPKKKTEVTTEE 14567
Query: 155 VAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRV-CPEPPLGLAIPID---PEKNRKEA 210
V E T+ +P ++ + +P+ K TE + PE + I + +K +K+
Sbjct: 14568 VVEEVTI-KKPEVIEEVTVKKPEEKIEEITEEVTIKKPEEKVVEEITEEVQIKKKPKKKP 14626
Query: 211 EPNESNAEHPRACPEPPLGLA------IPIDPEKNKGENLTPTDENELDRRNRREELVAL 264
EP +P +A I + + K E +T + + + + E +
Sbjct: 14627 EPKIEEVTEEVTLKKPEEKIAEEVTEEIVVKKAEEKVEEVTEEVQIKRKPKKKPEPKIEE 14686
Query: 265 VTSDEKIVNPRD 276
VT + I P +
Sbjct: 14687 VTEEVTIKKPEE 14698
Score = 45.4 bits (106), Expect = 0.005
Identities = 117/586 (19%), Positives = 215/586 (35%), Gaps = 60/586 (10%)
Query: 15 RRREEKPEPLPS------PEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVA 68
++ EEK E + PE+ + +++ + KKK K+ PEP +
Sbjct: 14586 KKPEEKIEEITEEVTIKKPEEKVVEEITEEVQIKKKPKKK-------------PEPKIEE 14632
Query: 69 TAIPITLETPKEQGAEPI-EATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETS 127
+TL+ P+E+ AE + E VV ++ T + K++ +P+P+ E +E +
Sbjct: 14633 VTEEVTLKKPEEKIAEEVTEEIVVKKAEEKVEEVTEEVQIKRKPKKKPEPKIEEVTEEVT 14692
Query: 128 NTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPK-PKEPCSTEH 186
E T+ +KK ++ +E V+E T+ V V E + K+P T
Sbjct: 14693 IKKPEEVTEEVVIKKPEE----VVHEEVSEEVTIKKPEEKVVEEVTEEVQIKKKPKKTPE 14748
Query: 187 PRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIP----IDPEKNKGE 242
P++ E + + EK +E P+ PEP + PE+ E
Sbjct: 14749 PKI-EEVTEEVTLKKPEEKVVEEVTEEVKIKRKPKKKPEPKIEEVTEEVTIKKPEEKVIE 14807
Query: 243 NLTPTDENELDRRNRREEL---VALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVI 299
+T + EE+ V + +EKIV V +K P + +P P I
Sbjct: 14808 EVTEEVVIKKPEEKVHEEVSEEVTIKKPEEKIVEEVTEEVKIKRKP------KKKPEPKI 14861
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK--KRVL 357
+L + + TE+ + + K + K + + ++ + PE K + V
Sbjct: 14862 EEVTEEVTLKKPEEKVIEEVTEEVV-----IRKPEEKVVEEVSEEVTIKKPEEKVVEEVT 14916
Query: 358 DREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLS 417
+ + K PE + + + P + E + K++ KKK
Sbjct: 14917 EEVKIKMKPKKKPEPKIEEVTEEV-----TIKKPEEKIDEEITEEVQIKRKPKKKPEPKI 14971
Query: 418 EGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNN 477
E +P E V++ + + +P + + + P E K+
Sbjct: 14972 EEVTEEVTIKKPKEKVVEEITEEVVIKKPEEKVPEEVSEEVTIKKP---EEKVVEEVTEE 15028
Query: 478 VLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQR- 536
V + +K +P V + V IK P + V I K E K+ +
Sbjct: 15029 VKIKMKLKKKPEPKIEEVTEEVT-IKKPEEKIDEEITEEVQIKRKPKKKPEPKIEEVTEE 15087
Query: 537 ---RKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVK 579
RK + A++ +E V + V ++K E K V+
Sbjct: 15088 VTLRKPKEEAIEEI-TEEVTIKKPEEKIEEVSEEVTIKKPEEKVVE 15132
Score = 43.5 bits (101), Expect = 0.017
Identities = 72/374 (19%), Positives = 145/374 (38%), Gaps = 42/374 (11%)
Query: 8 ELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKI----KEEGIESHEHDQVLLPE 63
E+ + +R+ K +P P E+ E+ KK +++ EE + ++V + +
Sbjct: 14665 EVTEEVQIKRKPKKKPEPKIEEVTEEVTIKKPEEVTEEVVIKKPEEVVHEEVSEEVTIKK 14724
Query: 64 P---VVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPE 120
P VV + ++ ++ EP V V ++P + ++ +E ++ +P+ +
Sbjct: 14725 PEEKVVEEVTEEVQIKKKPKKTPEPKIEEVTEEVTLKKPEEKVVEEVTEEVKIKRKPKKK 14784
Query: 121 PEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKE 180
PEPK E T+ ++KK +++ E E V V+ +P+ K
Sbjct: 14785 PEPK------IEEVTEEVTIKKPEEKVIEEVTEEV----------------VIKKPEEK- 14821
Query: 181 PCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNK 240
H V E + I EK +E P+ PEP + K
Sbjct: 14822 ----VHEEVSEE----VTIKKPEEKIVEEVTEEVKIKRKPKKKPEPKIEEVTEEVTLKKP 14873
Query: 241 GENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLV-PLKSIPGFVLEQQTQPGPVI 299
E + E+ R E++V V+ + I P + +V + ++ + +P P I
Sbjct: 14874 EEKVIEEVTEEVVIRKPEEKVVEEVSEEVTIKKPEEKVVEEVTEEVKIKMKPKKKPEPKI 14933
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK--KRVL 357
++ + I TE+ KR + K ++ + ++ + P+ K + +
Sbjct: 14934 EEVTEEVTIKKPEEKIDEEITEEVQIKR-KPKKKPEPKIEEVTEEVTIKKPKEKVVEEIT 14992
Query: 358 DREEPNKCNAKLPE 371
+ K K+PE
Sbjct: 14993 EEVVIKKPEEKVPE 15006
Score = 41.6 bits (96), Expect = 0.065
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 23/174 (13%)
Query: 20 KPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESH------EHDQVLLPEPVVVATAIPI 73
KP+ P P+ ++ S R+++ K++E + H E Q + V+ I I
Sbjct: 15284 KPKKKPEPKYEEVSSEVTIMRKREDKVEEVVEDVHIKMKPKEKPQEKFDD---VSEEITI 15340
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
+ KEQ E I V + ++ ++ +E + + EP E ++ S T
Sbjct: 15341 SKPETKEQVTEEITEDVQIKLKPKKKPDIRTEEVTEEVTIIRKEEPSEEEEDISET---- 15396
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEP------PAVQGGVLPEPKPKEP 181
+K+K KRK E V E+ +P + +L PKPK+P
Sbjct: 15397 ----VQIKRKPKRKITTKEEEVTEVTIQKPKPKEEPVEEVTEEFMLKRPKPKKP 15446
Score = 40.0 bits (92), Expect = 0.19
Identities = 44/178 (24%), Positives = 74/178 (40%), Gaps = 28/178 (15%)
Query: 5 SQSELLHSKKRRREEKPEPLPSPEQDQ----------EQSCSKKKRRKKKKIKEEGIESH 54
++ E+L K E+ +P P P++ E+ K++ K KK+++ +
Sbjct: 7978 TEPEILDKDKVPLEKPLKPKPEPKEKPSMEPEVPKPVEEKPPKEEEPKPKKVRKRPEKKD 8037
Query: 55 EHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKE-TVL 113
E +V P +P PKE+ E I V+ P ++PA+ K K+
Sbjct: 8038 EEPEV----PSWRGRRLP-----PKEEEKEEI---VLKPFKKEKPAEPKPKPKRTPGKPY 8085
Query: 114 EPQ-PEPEPEPKETSNTDHSE----PTQLCSVKKKKKRKGAESNEAVAELATVCTEPP 166
EP+ PEPE P E + E P ++ KK +K E+ + + TE P
Sbjct: 8086 EPEIPEPEKPPLEPYSKPEKEKSPKPEEVLKKPSKKPKKIKEAEPKKPLVPVMATEVP 8143
Score = 38.5 bits (88), Expect = 0.55
Identities = 38/164 (23%), Positives = 69/164 (41%), Gaps = 18/164 (10%)
Query: 14 KRRREEKPE----------PLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPE 63
K + ++KPE + PE++ + +K +KK K E I E + P+
Sbjct: 15141 KMKPKKKPEFKVEEVSEEITIKKPEEEVAEEVQIRKPKKKSVFKTEEIS--EEITLQKPK 15198
Query: 64 PVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAK--THRKKKKKETVLEPQPEPEP 121
V +TL+ P+E+ E + V PD++ + T + K + ++P+ E E
Sbjct: 15199 EKVEEVTEEVTLKRPEEKIVEEVSEEVTIKKPDEKVVEEVTEEVQIKMKPKMKPKYEVEE 15258
Query: 122 EPKETS----NTDHSEPTQLCSVKKKKKRKGAESNEAVAELATV 161
+E + + E T+ K K K+K E V+ T+
Sbjct: 15259 VTEEMTIKQPEEEVEEITEEVRFKLKPKKKPEPKYEEVSSEVTI 15302
Score = 35.4 bits (80), Expect = 4.7
Identities = 40/162 (24%), Positives = 59/162 (35%), Gaps = 31/162 (19%)
Query: 17 REEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLE 76
++E PEP + E +E S K +RKK + EE E TL
Sbjct: 15460 KQESPEPTVTEEVTEEVSFRVKPKRKKPIVTEEISEE-------------------FTLR 15500
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQ---PEPEPEPKETSNTDHSE 133
PKE E P + + K+K K + E Q E E + E + H E
Sbjct: 15501 KPKEPEEEG---------PYEVSEEVTIKRKPKPFIRETQEISEEVEMKLTEPEDFTHEE 15551
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPE 175
T+ +K K+ +K E + V E + V+ E
Sbjct: 15552 TTEDVKIKMKRPKKKYSVTEETIDSKMVIQESDEEEPEVIYE 15593
>UniRef100_O45544 Hypothetical protein F49E2.5d [Caenorhabditis elegans]
Length = 889
Score = 76.6 bits (187), Expect = 2e-12
Identities = 117/591 (19%), Positives = 209/591 (34%), Gaps = 66/591 (11%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKK------RRKKKKIKEEGIESHEHDQ- 58
Q + + K+ ++K + + + + EQ + KK RR + + K+ + EH Q
Sbjct: 63 QPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKAAEKEARRAEAEAKKRAAQEEEHKQW 122
Query: 59 ------VLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPD-QRPAKTHRKKKKKET 111
+ + A + E KE+ + +A PA + K+
Sbjct: 123 KAEQERIQKEQEKKEADLKKLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVKKV 182
Query: 112 VLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGG 171
+ P PEPK +NT Q+ + KK +K + +E+ A A P +V+
Sbjct: 183 ANDRSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAA-----PASVEQV 237
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLA 231
V E P+V E P A P +KN+K +ES E+ A E P+
Sbjct: 238 V------------EQPKVVTEEPHQQAAP-QEKKNKKNKRKSES--ENVPAASETPVEPV 282
Query: 232 IPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHL-----VPLKSIPG 286
+ P ++ + D+ + + EE V K D++ V K P
Sbjct: 283 VETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFVTAKEEPK 342
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN 346
+T PV V N + + T P +K NK+ + K + +++ P +
Sbjct: 343 DE-PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDK-KKSESEKVTEQPVESA 400
Query: 347 TEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWK 406
PP+ ++ V E+P +K P N + + + P +
Sbjct: 401 PAPPQVEQVVEKVEKPVAPVSKKPTA---DDNMDFLDFVTAKPEKTESVEEHIEAPMIVE 457
Query: 407 KRAKKKNVLLSEGGK------SNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDL 460
+ + GGK N+ N + TP + V + ++ P
Sbjct: 458 PVHAENETAAAAGGKKKNKKNKNKKNSESESTPAAEPVKEVTPEIVEEVFEKKTITPSTA 517
Query: 461 ATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPID 520
A + G N K N++ +E+ + P+K + P + ++
Sbjct: 518 AAAAPAPGSKKN------------KKNKKNSESESAPAAEPVK--EVTPEI-VEEVFEKK 562
Query: 521 LATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLK 571
TP +E + A KKNK+ K + H ++ Q TE K
Sbjct: 563 TVTPS-TEAAAAPASASKKNKKNKKGSGISESHDTAPAPTVEIPQTTEGGK 612
Score = 47.8 bits (112), Expect = 0.001
Identities = 60/251 (23%), Positives = 98/251 (38%), Gaps = 51/251 (20%)
Query: 342 PDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKT 401
P EP E + + ++ NK N K E+ A+ ++Q + P V T H+
Sbjct: 197 PTNTPAEPAEQVQEITGKK--NKKNKKKSESEATAAPASVEQVV---EQPKVVTEEPHQQ 251
Query: 402 PKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLA 461
+K+ KKN SE +E+ +ETPV+ P+
Sbjct: 252 AAPQEKK-NKKNKRKSE----SENVPAASETPVE---------------------PVVET 285
Query: 462 TPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSID-------PTLPTD 514
TP SE + N + + SE K E+P + KS P ++D P D
Sbjct: 286 TPPASENQKKN--KKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFVTAKEEPKD 343
Query: 515 QPV-----PIDLATPKHSEGKMSKA------QRRKKNKRALKSAWSESVHHSSDQNAKTP 563
+P P++ E + K+ + +KKNK+ K + SE V ++A P
Sbjct: 344 EPAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKVTEQPVESAPAP 403
Query: 564 VQRTESLKLVE 574
Q + ++ VE
Sbjct: 404 PQVEQVVEKVE 414
Score = 47.0 bits (110), Expect = 0.002
Identities = 119/604 (19%), Positives = 210/604 (34%), Gaps = 112/604 (18%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP 62
S S++ + + E+P+ + Q KK ++ K+K + E
Sbjct: 223 SESEATAAPASVEQVVEQPKVVTEEPHQQAAPQEKKNKKNKRKSESEN------------ 270
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPE-P 121
+P ETP EP+ T +Q+ K +KK + E V+E + E P
Sbjct: 271 --------VPAASETP----VEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAP 318
Query: 122 EPKETSNTDHSEPTQLCSVKKKKKRKGAESNEA---------VAELATVCTEPPAVQGGV 172
+ K+ + D+ + + K++ K + AE+ A V + T PPA +
Sbjct: 319 KSKKPTADDNMDFLDFVTAKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKK 378
Query: 173 LPEPKPKEPCS---TEHP-RVCPEPPLGLAI------PIDPEKNRKEAEPNESNAEHPRA 222
+ K+ S TE P P PP + P+ P + A+ N + A
Sbjct: 379 KNKKDKKKSESEKVTEQPVESAPAPPQVEQVVEKVEKPVAPVSKKPTADDNMDFLDFVTA 438
Query: 223 CPEPPLG----LAIPIDPEKNKGENLTPT-----DENELDRRNRREELVALVTSDE-KIV 272
PE + P+ E EN T +N+ ++ + E + ++ K V
Sbjct: 439 KPEKTESVEEHIEAPMIVEPVHAENETAAAAGGKKKNKKNKNKKNSESESTPAAEPVKEV 498
Query: 273 NPR--DHLVPLKSI-PGFVLEQQTQPG--------------------PVIPVCPNSASLI 309
P + + K+I P PG PV V P +
Sbjct: 499 TPEIVEEVFEKKTITPSTAAAAAPAPGSKKNKKNKKNSESESAPAAEPVKEVTPEIVEEV 558
Query: 310 GQSQTI-PVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEP------PETK---KRVLDR 359
+ +T+ P + S+ +K K K+ + + + H+T P P+T K
Sbjct: 559 FEKKTVTPSTEAAAAPASASKKNK-KNKKGSGISESHDTAPAPTVEIPQTTEGGKGSPGS 617
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEG 419
++ N +A S +D +P + T + K KK KK K + +SE
Sbjct: 618 DKENSGSAVNGSAKKQMSVEELDYGVPGQT---TDTTTDKKNKKKNKK--GKNSNSISEN 672
Query: 420 GK-----SNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQ 474
+ +H Q + VQ + S PI + SE + +
Sbjct: 673 AQVIAHLEQDHLDQMADDEVQAITGAAGSHS----------PPIQVHEVTSSEQHSNGVE 722
Query: 475 RNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKA 534
+N + ++T QK+V + + TL V ID + ++ K
Sbjct: 723 KNTTIEITQAVDGTDMSQTQFQKNVEKL----VQATLAKHDIVEIDPTVKLRIDAQLIKL 778
Query: 535 QRRK 538
+K
Sbjct: 779 SEKK 782
>UniRef100_O45543 Hypothetical protein F49E2.5f [Caenorhabditis elegans]
Length = 611
Score = 73.6 bits (179), Expect = 2e-11
Identities = 124/592 (20%), Positives = 217/592 (35%), Gaps = 119/592 (20%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKK------RRKKKKIKEEGIESHEHDQ- 58
Q + + K+ ++K + + + + EQ + KK RR + + K+ + EH Q
Sbjct: 63 QPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKAAEKEARRAEAEAKKRAAQEEEHKQW 122
Query: 59 ------VLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPD-QRPAKTHRKKKKKET 111
+ + A + E KE+ + +A PA + K+
Sbjct: 123 KAEQERIQKEQEKKEADLKKLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVKKV 182
Query: 112 VLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGG 171
+ P PEPK +NT Q+ + KK +K + +E+ A A P +V+
Sbjct: 183 ANDRSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAA-----PASVEQV 237
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLA 231
V E P+V E P A P +KN+K +ES E+ A E P+
Sbjct: 238 V------------EQPKVVTEEPHQQAAP-QEKKNKKNKRKSES--ENVPAASETPVEPV 282
Query: 232 IPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHL-----VPLKSIPG 286
+ P ++ + D+ + + EE V K D++ V K P
Sbjct: 283 VETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFVTAKEEPK 342
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN 346
+T PV V N + + T P +K NK+ + K + +++ P +
Sbjct: 343 DE-PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDK-KKSESEKVTEQPVESA 400
Query: 347 TEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWK 406
PP+ ++ V T P KK
Sbjct: 401 PAPPQVEQ-------------------------------------VVETTPPASENKKKN 423
Query: 407 KRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLP-----TDQPVPIDLA 461
K+ KKK SE K+ E PVQ + S P+ D ++ T +P ++A
Sbjct: 424 KKDKKK----SESEKA-------VEEPVQAAPSS-KKPTADDSMDFLDFVTAKPDRSEVA 471
Query: 462 TPKHSEGKMSNAQRNNVLLSEGVKSN---------EQPTETPVQKSVNPIKAPSIDPTLP 512
P +++ + + SE K N E+ E PVQ + K P+ D ++
Sbjct: 472 APV----EVAKVDESTAVTSENRKKNKKDKKKSESEKAVEEPVQAAPTS-KKPTADDSMD 526
Query: 513 TDQPVPIDLATPKHSEGK-----MSKAQRRKKNKRALKSAWSESVHHSSDQN 559
+D T K + + + +KK+K++ K++ SES ++D +
Sbjct: 527 F-----LDFVTAKEERVEEVAPVQEQVKEQKKSKKSKKTSESESKRPTADDS 573
Score = 68.2 bits (165), Expect = 7e-10
Identities = 129/584 (22%), Positives = 212/584 (36%), Gaps = 146/584 (25%)
Query: 18 EEKPEPLPSPE-QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLE 76
+++ E S E +Q Q K K+ +KKK +++ + HE +Q + + A E
Sbjct: 49 DQRKEAFASLELTEQPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKAAEKEARRAEAE 108
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQ 136
K E H + ++++KKE L+ + + E + ++ + +E
Sbjct: 109 AKKRAAQEE-----EHKQWKAEQERIQKEQEKKEADLK-KLQAEKKKEKAVKAEKAE--- 159
Query: 137 LCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLG 196
K +K K A + V E + + A P P+PK P +T P P
Sbjct: 160 -----KAEKTKKASTPAPVEE--EIVVKKVANDRSAAPAPEPKTPTNT------PAEPAE 206
Query: 197 LAIPIDPEKNRKEAEPNESNA-----------EHPRACPEPPLGLAIPIDPEKNKGENLT 245
I +KN+K + +ES A E P+ E P A P + +KNK
Sbjct: 207 QVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKVVTEEPHQQAAPQE-KKNKKNKRK 265
Query: 246 PTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNS 305
EN VP S +T PV+
Sbjct: 266 SESEN----------------------------VPAAS--------ETPVEPVV------ 283
Query: 306 ASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLD------- 358
+T P QK NK+ K K + + + E P++KK D
Sbjct: 284 -------ETTPPASENQKKNKKD---KKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLD 333
Query: 359 ----REEPNKCNAKLPETLM--LASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK 412
+EEP A+ P + + N ++ + + P P K KK KK+++ +
Sbjct: 334 FVTAKEEPKDEPAETPAAPVEEVVENV-VENVVEKSTTP--PATENKKKNKKDKKKSESE 390
Query: 413 NVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSN 472
V TE PV+ + +P P ++ + T TP SE K N
Sbjct: 391 KV---------------TEQPVESAPAP---PQVEQVVET---------TPPASENKKKN 423
Query: 473 AQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLP-----TDQPVPIDLATP--- 524
+ + +E+ E PVQ + + K P+ D ++ T +P ++A P
Sbjct: 424 KK------DKKKSESEKAVEEPVQAAPSS-KKPTADDSMDFLDFVTAKPDRSEVAAPVEV 476
Query: 525 -KHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRT 567
K E ++ RKKNK+ K + SE Q A T + T
Sbjct: 477 AKVDESTAVTSENRKKNKKDKKKSESEKAVEEPVQAAPTSKKPT 520
Score = 48.5 bits (114), Expect = 5e-04
Identities = 88/420 (20%), Positives = 158/420 (36%), Gaps = 89/420 (21%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP 62
S S++ + + E+P+ + Q KK ++ K+K + E
Sbjct: 223 SESEATAAPASVEQVVEQPKVVTEEPHQQAAPQEKKNKKNKRKSESEN------------ 270
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPE-P 121
+P ETP EP+ T +Q+ K +KK + E V+E + E P
Sbjct: 271 --------VPAASETP----VEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAP 318
Query: 122 EPKETSNTDHSEPTQLCSVKKKKKRKGAESNEA---------VAELATVCTEPPAVQGGV 172
+ K+ + D+ + + K++ K + AE+ A V + T PPA +
Sbjct: 319 KSKKPTADDNMDFLDFVTAKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKK 378
Query: 173 LPEPKPKEPCS---TEHP-RVCPEPP-LGLAIPIDP--EKNRKEAEPNESNAEHPRACPE 225
+ K+ S TE P P PP + + P +N+K+ + ++ +E +A E
Sbjct: 379 KNKKDKKKSESEKVTEQPVESAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEE 438
Query: 226 PPLGLAIPIDPEKNKGENLTPTDENELD------RRNRREELVA-----------LVTSD 268
P + P K PT ++ +D + R E+ A VTS+
Sbjct: 439 P-----VQAAPSSKK-----PTADDSMDFLDFVTAKPDRSEVAAPVEVAKVDESTAVTSE 488
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQTQPGPVI--PVCPNSASLIG-------QSQTIPVVD 319
+ N +D KS +E+ Q P P +S + + + + V
Sbjct: 489 NRKKNKKD---KKKSESEKAVEEPVQAAPTSKKPTADDSMDFLDFVTAKEERVEEVAPVQ 545
Query: 320 TEQKINKRSRMSKMKRKRMNSMPDKHN--------TEPPETKKRVLDREEPNKCNAKLPE 371
+ K K+S+ SK + + P + T PE ++V++ E+P PE
Sbjct: 546 EQVKEQKKSKKSKKTSESESKRPTADDSMDFLDFVTAKPEKPEQVVE-EQPVVQEVPKPE 604
>UniRef100_UPI00004345B3 UPI00004345B3 UniRef100 entry
Length = 5609
Score = 72.8 bits (177), Expect = 3e-11
Identities = 134/584 (22%), Positives = 236/584 (39%), Gaps = 84/584 (14%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P P + +E+ ++ KKKK KE+ + ++V
Sbjct: 5049 QVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEV 5108
Query: 60 LLPEPV---VVATAIPITLETPKEQGAEPI------EATVVHPVPDQRPAK------THR 104
L +PV V I +E K + +P+ E T+ P P ++ + T +
Sbjct: 5109 TLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLK 5168
Query: 105 KKKKKE-TVLEPQPE----PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELA 159
KKK KE +VLE E +P PKE E T+ +KK KK+K E EA E+
Sbjct: 5169 KKKPKEKSVLEEVKEEVTLKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEIT 5224
Query: 160 TVCTEP------PAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE 211
EP ++ L + KPKE E V E L IP + PE+ ++ E
Sbjct: 5225 IKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLE--EVKEEVTLKKPIPKEKVPEEVTEQVE 5282
Query: 212 ---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSD 268
P + A E + P++ E+ + T+E L ++ +E+ V +
Sbjct: 5283 IKKPKKKKPVEEEAADEITIKKPEPVEKEEEE-----ITEEVTLKKKKPKEKPVLEEVKE 5337
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
E + +P + +P V EQ +P PV +A I + V E++I +
Sbjct: 5338 EVTLKKP---IPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPELVEKEEEEITE 5394
Query: 327 RSRMSKMKRKR---MNSMPDKHNTEPPETKKRVL----DREEPNKCNAKLPETLMLASNC 379
+ K K K + + ++ + P+ K++VL ++ E K K P A
Sbjct: 5395 DITLKKKKPKEKPVLEEVTEEITLKKPKEKEKVLEEVTEKIEVKKSKKKKPIVEEAADEV 5454
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVS 439
I + + ++ E + P++ R K K + E E + T T +
Sbjct: 5455 TIKKIVEEETK-------EEEAPEEVVLRPKSKRKSIVE---EEEEVTEVTITKPKPVEE 5504
Query: 440 PINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSV 499
+ ++ L +PV E ++++ ++ +E + E P E ++K
Sbjct: 5505 EKKSKEVEVFLKKKKPV---------VEEEVADVTVKKLISTE---AEEVPEEFTIKKKK 5552
Query: 500 NPIKAPSIDPTLPTDQPVPIDLATP--KHSEGKMSKAQRRKKNK 541
P K P++ + + P + EG++S + KK K
Sbjct: 5553 KPEKKPTVPEEVEETAITIKKVRGPEERKEEGEVSTEIQIKKKK 5596
Score = 60.5 bits (145), Expect = 1e-07
Identities = 128/545 (23%), Positives = 208/545 (37%), Gaps = 76/545 (13%)
Query: 13 KKRRREEKPEPLPS------PEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVL-LP--- 62
K++ EEKPE + P++++E+ K KK+K +EE E + V LP
Sbjct: 1166 KEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPEEEKPEEVKLKPVKRLPKEE 1225
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPE 122
E V T P+ E P+E+ E ++ V +P + +++KK L+P + +PE
Sbjct: 1226 EEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKE-------EEEKKVVTLKPIKKEKPE 1278
Query: 123 PKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPC 182
++ E +L SVK+ K E + V L + E P E KP+E
Sbjct: 1279 EEKP------EEVKLKSVKRLPKE---EEEKEVVTLKPIKKEKPE-------EEKPEEVK 1322
Query: 183 STEHPRVCPEPPLGLAIPIDPEKNRK--EAEPNESNAEHPRACP----EPPLGLAIPID- 235
R+ E I + P K K E +P E + + P E + PI
Sbjct: 1323 LKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKKVVTLKPIKK 1382
Query: 236 --PEKNKGENLTPTDENELDRRNRREELVALVT-SDEKIVNPRDHLVPLKSIPGFVLEQQ 292
PE+ K E + L + +E+V L EK + V LK + E++
Sbjct: 1383 EKPEEEKPEEVKLKSVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEE 1442
Query: 293 TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMP---DKHNTEP 349
+ VI + P + + V + K KR + +++ + P +K E
Sbjct: 1443 EKE--VITLKPVKKEKPEEEKPEEV---KLKPVKRLHKEEDEKEVVTLKPLKKEKPEEEK 1497
Query: 350 PETKK----RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKW 405
PE K + L +EE K E ++L I + P + P K P+K
Sbjct: 1498 PEEVKLKPVQRLPKEEEEK------EEVILKP---IKKEKPEEEKPEEVKLKPVKRPEK- 1547
Query: 406 KKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH 465
K K + V L K +H + E ++ PI + P + + PK
Sbjct: 1548 PKEEKPEEVKL----KPVKHLPKEEEENEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKE 1603
Query: 466 SEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPK 525
E K V+ + VK + E P + + PIK + P + + PK
Sbjct: 1604 EEEK-------EVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEEEKPEEVKLKPVKRLPK 1656
Query: 526 HSEGK 530
E K
Sbjct: 1657 EEEEK 1661
Score = 59.7 bits (143), Expect = 2e-07
Identities = 117/565 (20%), Positives = 221/565 (38%), Gaps = 50/565 (8%)
Query: 29 QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEA 88
++ ++ + KK K+K+ EE E E + +PV A IT++ P+ E E
Sbjct: 4871 EEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEI 4930
Query: 89 TVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKG 148
T + ++P + ++ KE V +P P+ + E E T+ +KK KK+K
Sbjct: 4931 TEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPE-------EVTEQVEIKKPKKKKP 4983
Query: 149 AESNEA----VAELATVCTEPPAVQGGV-LPEPKPKEPCSTEHPRVCPEPPLGLAIPID- 202
E A + + ++ E + V L + KPKE E V E L IP +
Sbjct: 4984 VEEEAADEITIKKPVSIEKEEEEITEEVTLKKKKPKEKPVLE--EVKEEVTLKKPIPKEK 5041
Query: 203 -PEKNRKEAE---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRR 258
PE+ ++ E P + A E + PI+ E+ + +E L ++ +
Sbjct: 5042 VPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEE-----IIEEVTLKKKKPK 5096
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIP 316
E+ V +E + VP + +P + EQ +P PV +A I + P
Sbjct: 5097 EKSVLEEVKEEVTLKKP---VPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEP 5153
Query: 317 VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLA 376
+ E++I + + K K K + + + + T K+ + +E K+PE +
Sbjct: 5154 IEKEEEEIIEEVTLKKKKPKEKSVLEE---VKEEVTLKKPVPKE-------KVPEEI--- 5200
Query: 377 SNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQK 436
++ P P + T KK + K++ ++ E + + + K
Sbjct: 5201 -TEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVK 5259
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEG-KMSNAQRNNVLLSEGV-KSNEQPTETP 494
+ P +P + +++ PK + + A + E V K E+ TE
Sbjct: 5260 EEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEV 5319
Query: 495 VQKSVNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSES 551
K P + P ++ + +P+P + + +E + ++ KK K + A E
Sbjct: 5320 TLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTE--QVEIKKPKKKKPVEEEAADEI 5377
Query: 552 VHHSSDQNAKTPVQRTESLKLVEAK 576
+ K + TE + L + K
Sbjct: 5378 TIKKPELVEKEEEEITEDITLKKKK 5402
Score = 58.5 bits (140), Expect = 5e-07
Identities = 94/375 (25%), Positives = 158/375 (42%), Gaps = 56/375 (14%)
Query: 19 EKPEPLPSPEQD-QEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPV---VVATAIPIT 74
+KP + E++ E+ KKK+ K+K + EE ++V L +P+ V I
Sbjct: 4995 KKPVSIEKEEEEITEEVTLKKKKPKEKPVLEE-----VKEEVTLKKPIPKEKVPEEITEQ 5049
Query: 75 LETPKEQGAEPI------EATVVHPVPDQRPAK------THRKKKKKE-TVLEPQPE--- 118
+E K + +P+ E T+ P P ++ + T +KKK KE +VLE E
Sbjct: 5050 VEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEVT 5109
Query: 119 -PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEP------PAVQGG 171
+P PKE E T+ +KK KK+K E EA E+ EP ++
Sbjct: 5110 LKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEITIKKPEPIEKEEEEIIEEV 5165
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE---PNESNAEHPRACPEP 226
L + KPKE E V E L +P + PE+ ++ E P + A E
Sbjct: 5166 TLKKKKPKEKSVLE--EVKEEVTLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEI 5223
Query: 227 PLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPG 286
+ PI+ E+ + +E L ++ +E+ V +E + +P + +P
Sbjct: 5224 TIKKPEPIEKEEEE-----IIEEVTLKKKKPKEKSVLEEVKEEVTLKKP---IPKEKVPE 5275
Query: 287 FVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR---MNSM 341
V EQ +P PV +A I + PV E++I + + K K K + +
Sbjct: 5276 EVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEVTLKKKKPKEKPVLEEV 5335
Query: 342 PDKHNTEPPETKKRV 356
++ + P K++V
Sbjct: 5336 KEEVTLKKPIPKEKV 5350
Score = 58.2 bits (139), Expect = 7e-07
Identities = 134/606 (22%), Positives = 229/606 (37%), Gaps = 86/606 (14%)
Query: 13 KKRRREEKPEP--------LPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEP 64
K++ EEKPE LP E+++E+ K KK+K +EE E + V P
Sbjct: 1003 KEKPEEEKPEEVKLKPVQRLPKEEEEKEEVILKPI--KKEKPEEEKPEEVKLKPVKRP-- 1058
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPK 124
E PKE+ E ++ +P K K+++++ V+ +P + +P+
Sbjct: 1059 -----------EKPKEEKPEEVKL---------KPVKHLPKEEEEKEVVTLKPIKKEKPE 1098
Query: 125 ETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCST 184
E + E +L VK+ K E + V L + E P E KP+E
Sbjct: 1099 E----EKPEEVKLKPVKRLPKE---EEEKEVVTLKPIKKEKP-------EEEKPEEVKLK 1144
Query: 185 EHPRVCPEPPLGLAIPIDPEKNRK--EAEPNESNAEHPRACP----EPPLGLAIPI---D 235
R+ E I + P K K E +P E + + P E + P+
Sbjct: 1145 PVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEK 1204
Query: 236 PEKNKGENLTPTDENELDRRNRREELVAL-VTSDEKIVNPRDHLVPLKSIPGFVLEQQTQ 294
PE+ K E + L + +E++ L EK + V LK + E++ +
Sbjct: 1205 PEEEKPEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEK 1264
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKK 354
V+ + P I + + E K+ R+ K + ++ E PE +K
Sbjct: 1265 --KVVTLKP-----IKKEKPEEEKPEEVKLKSVKRLPKEEEEKEVVTLKPIKKEKPEEEK 1317
Query: 355 RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNP-AVPTNPEHKTPKKWKKRAKKKN 413
+ +P K K E + + + + P + P V P + P K+ +KK
Sbjct: 1318 PEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLP---KEEEEKKV 1374
Query: 414 VLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDL-ATPKHSEGKMSN 472
V L K +P E + KSV + + + T +P+ + K E K+
Sbjct: 1375 VTLKPIKKEKPEEEKPEEVKL-KSVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKP 1433
Query: 473 AQR-------NNVLLSEGVKSNEQPTETPVQKSVNPIK---APSIDPTLPTDQPVPIDL- 521
+R V+ + VK + E P + + P+K + + T +P+ +
Sbjct: 1434 VKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLHKEEDEKEVVTLKPLKKEKP 1493
Query: 522 ATPKHSEGKMSKAQR-----RKKNKRALKSAWSESVHHSSDQNAK-TPVQRTESLKLVEA 575
K E K+ QR +K + LK E + K PV+R E K +
Sbjct: 1494 EEEKPEEVKLKPVQRLPKEEEEKEEVILKPIKKEKPEEEKPEEVKLKPVKRPEKPKEEKP 1553
Query: 576 KSVKAK 581
+ VK K
Sbjct: 1554 EEVKLK 1559
Score = 57.8 bits (138), Expect = 9e-07
Identities = 95/439 (21%), Positives = 171/439 (38%), Gaps = 46/439 (10%)
Query: 13 KKRRREEKPEPLPS------PEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVL-LP--- 62
K++ EEKPE + P++++E+ K KK+K +EE E + V LP
Sbjct: 1346 KEKPEEEKPEEVKLKPVKRLPKEEEEKKVVTLKPIKKEKPEEEKPEEVKLKSVKRLPKEE 1405
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAK---THRKKKKKETVLEPQPEP 119
E V T PI E P+E+ E ++ V +P + K T + KK++ E E
Sbjct: 1406 EEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEV 1465
Query: 120 EPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ--GGVLPEPK 177
+ +P + + + E ++ ++K KK K E +L V P + V+ +P
Sbjct: 1466 KLKPVKRLHKEEDE-KEVVTLKPLKKEKPEEEKPEEVKLKPVQRLPKEEEEKEEVILKPI 1524
Query: 178 PKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPI--- 234
KE E P P + P P++ + E + P+ E + PI
Sbjct: 1525 KKEKPEEEKPEEVKLKP--VKRPEKPKEEKPEEVKLKPVKHLPKEEEENEVVTLKPIKKE 1582
Query: 235 DPEKNKGENLTPTDENELDRRNRREELVAL-VTSDEKIVNPRDHLVPLKSIPGFVLEQQT 293
PE+ K E + L + +E+V L EK + V LK I E++
Sbjct: 1583 KPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEEEK 1642
Query: 294 QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH-------- 345
+ + + + + +++ + + ++K K + +P +
Sbjct: 1643 PEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTL 1702
Query: 346 ---NTEPPETKK----RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPE 398
E PE +K ++ + P K + PE + L + IP + V PE
Sbjct: 1703 KPIKKEKPEEEKPEEVKLKPVKRPEKPKEEKPEEVKL-------KPIPKSVSEKVEEKPE 1755
Query: 399 HKTPK--KWKKRAKKKNVL 415
+ K W++ K K ++
Sbjct: 1756 DEAEKILPWRRGKKTKKIV 1774
Score = 55.5 bits (132), Expect = 4e-06
Identities = 116/535 (21%), Positives = 192/535 (35%), Gaps = 78/535 (14%)
Query: 25 PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAE 84
P+ Q+ E S + ++ K KK+K + ++ E + + E V + P E+G E
Sbjct: 4113 PNYVQNGELSRTMEEALKLKKMKHKKVKFPEKE---ITELEKVDQEFEKLKKIPLEKGEE 4169
Query: 85 --PIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEP-----KETSNTDHSEPTQL 137
P E P + ++ + KK K +P+ E EP K+ S P +L
Sbjct: 4170 IAPYERK-----PKSKESEEEKPKKLKIGKGKPRSAEEEEPEIIKLKKIPEKVPSVPEKL 4224
Query: 138 CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGL 197
+ KKK E + P+ KP EP E + E L
Sbjct: 4225 APIAKKKDEVDKPEKEKEEK--------------EYPKLKPFEPYEIETTEIELEELEEL 4270
Query: 198 AIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNR 257
P PEK K+ + EH E A+PI P K P +E E+ RR
Sbjct: 4271 EYPKKPEKVPKKMLTKKPKKEHKTPVQETE---AVPIVPGVPKPRE--PQEEEEIKRRIP 4325
Query: 258 REELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPV 317
E A EKI L P K P EQ+ +P + P ++ + +
Sbjct: 4326 ESE--ASKEKPEKI-----KLKPWKK-PEEEKEQEKKPEYYLKFVPKDDDIVETVEIVTT 4377
Query: 318 VDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDRE---EPNKCNAKLPETLM 374
V+ E+ K+ R K+K+K+ + K E P+ + + E EP ++ E +
Sbjct: 4378 VNMEETPEKKQR--KIKKKKTTT---KRGDEKPKVIEEITIEEEGVEPMVTVEEIVEDKL 4432
Query: 375 LASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSN----------- 423
A + + + +P + E + KK +KK V GK
Sbjct: 4433 EAVSIEL-KPVPIEEIKEEIVTSEIMSEDGAKKTVRKKRVTKKREGKEQITEEVIVEEEE 4491
Query: 424 ----------EHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNA 473
E + E P++K V P + I + ++ + E S
Sbjct: 4492 PEMMKLKKIPEKKPEKIEEPLKKPVKPESEEKIKAEKKEKPKMKLEHEELRPLEFDKSEL 4551
Query: 474 QRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSE 528
++ + E + +E+P P+ K K D + + +P+ PK E
Sbjct: 4552 EK---YVPEEHEESEKPPPEPMPKPYEREKKKKPDQEI---EQIPLIKGEPKLPE 4600
Score = 51.6 bits (122), Expect = 6e-05
Identities = 115/577 (19%), Positives = 212/577 (35%), Gaps = 99/577 (17%)
Query: 13 KKRRREEKPEPLPS------PEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL----P 62
K++ EEKPE + P++++E+ K KK+K +EE E + V
Sbjct: 1418 KEKPEEEKPEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLHKEE 1477
Query: 63 EPVVVATAIPITLETPKEQGAEPI---------------EATVVHPVPDQRPAKTHRKKK 107
+ V T P+ E P+E+ E + E ++ P+ ++P + ++
Sbjct: 1478 DEKEVVTLKPLKKEKPEEEKPEEVKLKPVQRLPKEEEEKEEVILKPIKKEKPEEEKPEEV 1537
Query: 108 KKETVLEPQPEPEPEPKET---------SNTDHSEPTQLCSVKKKK-------------- 144
K + V P+ E +P+E + +E L +KK+K
Sbjct: 1538 KLKPVKRPEKPKEEKPEEVKLKPVKHLPKEEEENEVVTLKPIKKEKPEEEKPEEVKLKPV 1597
Query: 145 KRKGAESNE-AVAELATVCTEPPAVQ--GGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPI 201
KR E E V L V E P + V +P KE E P P+ +P
Sbjct: 1598 KRLPKEEEEKEVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEEEKPEEVKLKPV-KRLPK 1656
Query: 202 DPEKNR-------KEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDR 254
+ E+ K+ +P E E + P L P + E+ + L P + + +
Sbjct: 1657 EEEEKEVVTLKPVKKEKPEEEKPEEVKLKPVKRL----PKEEEEKEVVTLKPIKKEKPEE 1712
Query: 255 RNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQ-----QTQPGPVIP--VCPNSAS 307
E + V EK + V LK IP V E+ + + ++P +
Sbjct: 1713 EKPEEVKLKPVKRPEKPKEEKPEEVKLKPIPKSVSEKVEEKPEDEAEKILPWRRGKKTKK 1772
Query: 308 LIGQSQTIPVVDTEQK-------------INKRSRMSKMKRKRMNSMPDKHNTEPPETKK 354
++ + + VV +Q+ + ++ K+ + + ++ P T K
Sbjct: 1773 IVDFREEVTVVPIDQEKVITEIHDEEIKIVEQKVEAKKIVQAEIKEFKEEKPELPWRTTK 1832
Query: 355 RVLD-REEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKN 413
V + EE PET++ D S+ + + +K KK K+K
Sbjct: 1833 EVKEIIEEKVVVEEIKPETVLKEDEVIEDVTESSEVS--------WRKRRKPKKPEKEKE 1884
Query: 414 VLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNA 473
V+ + + +E + E V K P+ + ++ P+ L PK K+
Sbjct: 1885 VVELKPVEKHEEFVERIEEIVLK---PVEKEKFEEKPKEEELKPLKLEKPK----KLEEE 1937
Query: 474 QRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPT 510
+ ++E + + PV+K V+ + I+ T
Sbjct: 1938 EIEEEKVTEMLWKKPEEIPVPVEKEVSTQEVQVIEAT 1974
Score = 50.4 bits (119), Expect = 1e-04
Identities = 120/584 (20%), Positives = 212/584 (35%), Gaps = 84/584 (14%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
KK + E+P P + +E+ ++KK + K K++ E + E D+ L + V
Sbjct: 4503 KKPEKIEEPLKKPVKPESEEKIKAEKKEKPKMKLEHEELRPLEFDKSELEKYV------- 4555
Query: 73 ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLE----------PQPEPEPE 122
P+E E+ P P +P + +KKK + + + P+P+ EPE
Sbjct: 4556 -----PEEHE----ESEKPPPEPMPKPYEREKKKKPDQEIEQIPLIKGEPKLPEPDKEPE 4606
Query: 123 -----PKETSNTDHSEPTQLCSVKKKK------KRKGAESNEAVAELATVCTEPPAVQGG 171
P++ + E L KK K K A+ E A A +
Sbjct: 4607 VKFRIPQKEKPEEEPEKITLKGWKKDKPEDEDIKEFPAKEEEEEAPTAPKKEAEEIILKR 4666
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPE--PPLG 229
+ KPKE + E +P EK KE + + P E P +
Sbjct: 4667 KVKLKKPKEKATKEEEVTFKKP---------EEKKPKEVIEEITLKKEPEKSMEQVPEIF 4717
Query: 230 LAIPIDPEKNKGENLTPTDEN-ELDRRNRREELVALVTSDE--KIVNPR--DHLVPLKSI 284
+ P+ EK E T T+ + EE++ + E K V D + KSI
Sbjct: 4718 IKKPVVEEKEIEEKETITEVTLKKPEEKISEEIIEEIKKPEAKKPVKKETSDEITVKKSI 4777
Query: 285 PGFVLEQQTQPGPVIPVCPNSASLIGQ--SQTIPVVDTEQKINKRSRMSKMKRKRMNSMP 342
E++ ++ I + + I + ++K+++ ++ K K S+
Sbjct: 4778 VEEKKEEEIPEQIILKKKKPKEKPIPEEIKEEITLKKLKEKVSEEEQIEIKKPKEKKSV- 4836
Query: 343 DKHNTEPPETKKRVLDRE----EPNKCNAKLPETLMLASNCHIDQAIPSDSNP-AVPTNP 397
+K T KK V + E E K P + + + IP + P +
Sbjct: 4837 EKEATSEITIKKPVENEEEEILEEVTLKKKKPVLEEVKEEITLKKPIPKEKVPEEISEQI 4896
Query: 398 EHKTPKKWKK---------RAKKKNVLLSEGGKSNEH----NGQPTETPVQKSVS---PI 441
E K PKK K KK + E + E +P E PV + V +
Sbjct: 4897 EIKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEEVTLKKKKPKEKPVLEEVKEEVTL 4956
Query: 442 NAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGV---KSNEQPTETPVQKS 498
P +P + +++ PK + + + + + + V K E+ TE K
Sbjct: 4957 KKPIPKEKVPEEVTEQVEIKKPKKKK-PVEEEAADEITIKKPVSIEKEEEEITEEVTLKK 5015
Query: 499 VNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKK 539
P + P ++ + +P+P + + +E K ++KK
Sbjct: 5016 KKPKEKPVLEEVKEEVTLKKPIPKEKVPEEITEQVEIKKPKKKK 5059
Score = 48.9 bits (115), Expect = 4e-04
Identities = 128/599 (21%), Positives = 228/599 (37%), Gaps = 134/599 (22%)
Query: 38 KKRRKKKKIKEEGIESHEHDQVLLPE----PVVVATAIPITLETPKEQGAEPIEATVVHP 93
KK KKK IK G E + V + E P T PI E I + P
Sbjct: 2831 KKTTKKKIIKRRGKEQQVTEVVTVEEEGKAPETTVTEGPI----------EKIVEETIKP 2880
Query: 94 VPD-QRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESN 152
+P ++ A T ++ K++ + + +PK+T+ KK KR+G E
Sbjct: 2881 LPGLEKVAPTEVEEVKEQVTVTEEITKLGKPKKTTK------------KKIIKRRGKE-- 2926
Query: 153 EAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEP 212
+ V E+ TV E A + V P K T + P P L P + E+ +++
Sbjct: 2927 QQVTEVVTVEEEGKAPETTVTEGPIEKIVEET----IKPLPGLEKVAPTEVEEVKEQVTV 2982
Query: 213 NESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIV 272
E + LG P+K T + + RR + +++ +VT +E+
Sbjct: 2983 TEEITK---------LG-----KPKKT-------TKKKIIKRRGKEQQVTEVVTVEEEGK 3021
Query: 273 NPRDHLV--PLKSIPGFVLEQQTQPGPVIP-VCPNSASLIGQSQTIPVVDTEQKINKRSR 329
P+ ++ P++ I +E+ +P P + V P + + T+ ++I K +
Sbjct: 3022 APKTTVIEGPVEEI----VEETIKPLPGLEKVVPTEVEELKEQVTVT-----EEITKLGK 3072
Query: 330 MSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDS 389
K +K++ K E T+ ++ E K P+T ++ +++ +
Sbjct: 3073 PKKTTKKKIIKRRGK---EQQVTEVVTVEEE------GKAPKTTVIEGP--VEEIVEETI 3121
Query: 390 NP------AVPTNPEH------------------KTPKKW--KKRAKKKNVL----LSEG 419
P VPT E KT KK K+R K++ V + E
Sbjct: 3122 KPLPGLEKVVPTEVEELKEQVTVTEEITKLGKPKKTTKKKIIKRRGKEQQVTEVVTVEEE 3181
Query: 420 GKSNEHN--GQPTETPVQKSVSPINAPSIDPTLPTD-----QPVPID-----LATPKHSE 467
GK+ + P E V++++ P+ P ++ +PT+ + V + L PK +
Sbjct: 3182 GKAPKTTVIEGPVEEIVEETIKPL--PGLEKVVPTEVEEVKEQVTVTEEITKLGKPKKTT 3239
Query: 468 GKMSNAQRNN-------VLLSEGVKS-----NEQPTETPVQKSVNPIKAPSIDPTLPTDQ 515
K +R V + E K+ E P E V++++ P+ PT +
Sbjct: 3240 KKKIVKRRGKQQQVTEVVTVEEEGKAPETTVTEGPIEAIVEETIKPLPGLEKVPTEVEEV 3299
Query: 516 PVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVE 574
+ + EGK K ++K +R K + + ++ K PV L E
Sbjct: 3300 KEQVTVTEEVSQEGKPKKVTKKKVIRRKGKQQ-QVTEFVTIEEQGKAPVTSVTETPLEE 3357
Score = 47.0 bits (110), Expect = 0.002
Identities = 129/652 (19%), Positives = 235/652 (35%), Gaps = 128/652 (19%)
Query: 12 SKKRRREEKPEPLPSPEQDQEQ---------------------------SCSKKKRRKKK 44
SK++ + K +P PE+++EQ + + +K++
Sbjct: 4330 SKEKPEKIKLKPWKKPEEEKEQEKKPEYYLKFVPKDDDIVETVEIVTTVNMEETPEKKQR 4389
Query: 45 KIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHR 104
KIK++ + D+ +P V+ IT+E E+G EP+ TV V D+ A +
Sbjct: 4390 KIKKKKTTTKRGDE----KPKVIEE---ITIE---EEGVEPM-VTVEEIVEDKLEAVS-- 4436
Query: 105 KKKKKETVLEPQPEPEPEPKETSNTDH--SEPTQLCSVKKKKKRKGAESNEAVAELATVC 162
+E +P P E KE T SE +V+KK+ K E E + E V
Sbjct: 4437 --------IELKPVPIEEIKEEIVTSEIMSEDGAKKTVRKKRVTKKREGKEQITEEVIVE 4488
Query: 163 TEPPAVQG-GVLPEPKP-------KEPCSTEHPRVC-----PEPPLGL----AIPIDPEK 205
E P + +PE KP K+P E +P + L P++ +K
Sbjct: 4489 EEEPEMMKLKKIPEKKPEKIEEPLKKPVKPESEEKIKAEKKEKPKMKLEHEELRPLEFDK 4548
Query: 206 NRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKN-------------KGENLTPTDENEL 252
+ E E + E + PEP + P + EK KGE P + E
Sbjct: 4549 SELEKYVPEEHEESEKPPPEP---MPKPYEREKKKKPDQEIEQIPLIKGEPKLPEPDKEP 4605
Query: 253 DRRNR-------REELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNS 305
+ + R EE + K P D + I F +++ + P P
Sbjct: 4606 EVKFRIPQKEKPEEEPEKITLKGWKKDKPED-----EDIKEFPAKEEEEEAPTAP--KKE 4658
Query: 306 ASLIGQSQTIPVVDTEQKINKRSR-------------------MSKMKRKRMNSMPDKHN 346
A I + + + ++K K + K K M +P+
Sbjct: 4659 AEEIILKRKVKLKKPKEKATKEEEVTFKKPEEKKPKEVIEEITLKKEPEKSMEQVPEIFI 4718
Query: 347 TEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWK 406
+P +K + ++E + K PE ++ + P P + T KK
Sbjct: 4719 KKPVVEEKEIEEKETITEVTLKKPEE-KISEEIIEEIKKPEAKKPVKKETSDEITVKKSI 4777
Query: 407 KRAKKKNVLLSEGGKSNEHNGQPTETPVQKSV-SPINAPSIDPTLPTDQPVPIDLATPKH 465
KK+ + + + +P E P+ + + I + + ++ + I K
Sbjct: 4778 VEEKKEEEIPEQIILKKK---KPKEKPIPEEIKEEITLKKLKEKVSEEEQIEIKKPKEKK 4834
Query: 466 SEGKMSNAQRNNVLLSEGVKSNEQP-TETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATP 524
S K + ++ + + + V++ E+ E K P+ + + +P+P +
Sbjct: 4835 SVEKEATSE---ITIKKPVENEEEEILEEVTLKKKKPV-LEEVKEEITLKKPIPKEKVPE 4890
Query: 525 KHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAK 576
+ SE + ++ KK K + A E + K + TE + L + K
Sbjct: 4891 EISE--QIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEEVTLKKKK 4940
Score = 46.2 bits (108), Expect = 0.003
Identities = 130/599 (21%), Positives = 215/599 (35%), Gaps = 72/599 (12%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
K +EEKP L E+ E + R KKK I+++ E ++ + E V V+ P
Sbjct: 516 KIEEKEEKPLKLIEEEKPIESELPWR-RDKKKSIEQKVTEIPIEEKKVEEEQVEVSWRKP 574
Query: 73 ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHS 132
+ Q + + T + P ++ + K +K+E VL+P E PKE
Sbjct: 575 REKVMKEVQKEKVEDFTAIKLKPARKEKRPDEKIEKEEVVLKP---IEKIPKE------E 625
Query: 133 EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPE 192
E + ++K +K K P + G + E K + P ++ E
Sbjct: 626 EIIEEVTLKSEKLEK-----------------PETFENGEILEEKTELPWRRGKKKLAKE 668
Query: 193 PPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP----EKNKGENLTPTD 248
+ L + EK ++ + +H PE I + P EK K E
Sbjct: 669 -EVKLEQILKLEKQVSKSVEEQIIFKHKDEKPEEKEISEIKLKPVKHIEKPKEEKPEEVK 727
Query: 249 ENELDRRNRREELVALVT-SDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSAS 307
+ R + EE +VT K P + LK P +E+ + P
Sbjct: 728 LKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPELKLKPVKHIEKPEEEKPEEVKLKPVKR 787
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNA 367
L + + +V K K+ + + K + + P K E PE +K + +P K
Sbjct: 788 LPKEEEEKEMVTL--KPVKKEKPEEEKPEEVKLKPTK--KEKPEEEKPEEVKLKPVKRLP 843
Query: 368 KLPETLMLASNCHIDQAIPSDSNP-AVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHN 426
K E + + I + P + P V P + P K+ +K+ V L K
Sbjct: 844 KEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLP---KEEEEKEVVTLKPVKKEKPEE 900
Query: 427 GQPTET---PVQK-----------SVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSN 472
+P E PV++ ++ PI + P + + PK E K
Sbjct: 901 EKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEK--- 957
Query: 473 AQRNNVLLSEGVKSNEQPTETPVQKSVNPIK-APSIDPTLPTDQPVPIDLATP---KHSE 528
V+ + +K + E P + + P+K P + PI P K E
Sbjct: 958 ----EVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEE 1013
Query: 529 GKMSKAQR-----RKKNKRALKSAWSESVHHSSDQNAK-TPVQRTESLKLVEAKSVKAK 581
K+ QR +K + LK E + K PV+R E K + + VK K
Sbjct: 1014 VKLKPVQRLPKEEEEKEEVILKPIKKEKPEEEKPEEVKLKPVKRPEKPKEEKPEEVKLK 1072
Score = 42.4 bits (98), Expect = 0.038
Identities = 86/432 (19%), Positives = 166/432 (37%), Gaps = 97/432 (22%)
Query: 1 MDSHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVL 60
+D E+ KK + EEK E + +E+ KK + +KK+I+++ IE E L
Sbjct: 129 LDVTKIEEVKKLKKEKIEEKMEQ--TKPWTEEKITLKKSKPEKKEIEKKTIEIVE----L 182
Query: 61 LPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQR-----------------PAKTH 103
P + +P + ++ +P+ V + +++ +KT
Sbjct: 183 KPSKI---EKLPDRKSSLEKVDLKPVPTAVTEKITEKKIIEKTKYFEEEDTALLEVSKTE 239
Query: 104 RKKKKKETVLEPQPEPEPE-------------------PKETSNTDHSEPTQL--CSVKK 142
KK K+ +E +PE +P+ KET T +P+++ S++K
Sbjct: 240 ELKKMKKDKVEEKPEEKPKLWTEEKVTLKKTKPVKKEVEKETIETVELKPSKITKTSIRK 299
Query: 143 KKKRKGAESNEAVAELATVC---------TEPPAVQGGVLP----EPKPKE--------- 180
+ +R+ + E T+ E VQ +P E KP+E
Sbjct: 300 EIRREHVPEEKEKLEEVTLKPVKRIPREEEEKEEVQLKPIPKRKSEEKPREEVTLKSFQK 359
Query: 181 PCSTEHPRVCPE-PPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKN 239
P E PE PL + P PEK + + +P + R PE L + PEK
Sbjct: 360 PKQEEEKSKKPELKPLEKSKPEAPEKEKVQLKPFQ------REKPEEKLTIISQKLPEKT 413
Query: 240 KGENLTPTDENELDRRNRRE--------ELVALVTSDEKIVNPRDHLV-PLKSIPGFVLE 290
+ + + +E R+ ++ E VA +EK++ + + KSI ++
Sbjct: 414 QEKEIKEVEEISWRRKPKKPSISEESPVEKVAEKIVEEKVIKKEEETIEDFKSIALKPIK 473
Query: 291 QQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPP 350
++ +P + + ++ + I K ++ + + P+K E
Sbjct: 474 REKKPEE------------REDKEEIILKPVKHIKKEEESTEEIKLKPVEKPEKKIEEKE 521
Query: 351 ETKKRVLDREEP 362
E ++++ E+P
Sbjct: 522 EKPLKLIEEEKP 533
Score = 38.1 bits (87), Expect = 0.72
Identities = 119/617 (19%), Positives = 227/617 (36%), Gaps = 94/617 (15%)
Query: 7 SELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHE-HDQVLLPEPV 65
S+ + +R++E+ +P +E+ KK + +K+I E +E+ E ++ + V
Sbjct: 36 SKRIDETVQRKKEEVKPWT-----EEKVTLKKSKLDRKEIPRETLETVELKPSKIVKKEV 90
Query: 66 VVAT-------AIPITLETPKEQ-----------GAEPIEATVVHPVPDQRPAKTHRKKK 107
AT +IPI E E+ ++ T + V + K K +
Sbjct: 91 DKATLEKVDLKSIPIVTEKITEETISKSEYLEQEDTSMLDVTKIEEVKKLKKEKIEEKME 150
Query: 108 K-------KETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELAT 160
+ K T+ + +PE + K+T +P++ ++K RK + + + T
Sbjct: 151 QTKPWTEEKITLKKSKPEKKEIEKKTIEIVELKPSK---IEKLPDRKSSLEKVDLKPVPT 207
Query: 161 VCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHP 220
TE + ++ + K E T V L K K+ + E E P
Sbjct: 208 AVTEK-ITEKKIIEKTKYFEEEDTALLEVSKTEEL---------KKMKKDKVEEKPEEKP 257
Query: 221 RACPEPPLGLAIPIDPEKNKGENLTPTDE---NELDRRNRREELVALVTSDEKIVNPRDH 277
+ E + L +K + T E +++ + + R+E+ +EK
Sbjct: 258 KLWTEEKVTLKKTKPVKKEVEKETIETVELKPSKITKTSIRKEIRREHVPEEKEKLEEVT 317
Query: 278 LVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR 337
L P+K IP E++ IP +S+ P + K ++ + + K K+
Sbjct: 318 LKPVKRIPREEEEKEEVQLKPIPK--------RKSEEKPREEVTLKSFQKPKQEEEKSKK 369
Query: 338 MNSMP-DKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTN 396
P +K E PE +K L + K KL I Q +P +
Sbjct: 370 PELKPLEKSKPEAPEKEKVQLKPFQREKPEEKLTI---------ISQKLPEKTQEKEIKE 420
Query: 397 PEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPV 456
E + W+++ KK ++ S E P E +K V + T+ + +
Sbjct: 421 VEEIS---WRRKPKKPSI-------SEE---SPVEKVAEKIVEEKVIKKEEETIEDFKSI 467
Query: 457 PIDLATPKHSEGKMSNAQRNNVLLS--EGVKSNEQPTET----PVQKSVNPIKAPSIDPT 510
L K + + ++L + +K E+ TE PV+K I+ P
Sbjct: 468 A--LKPIKREKKPEEREDKEEIILKPVKHIKKEEESTEEIKLKPVEKPEKKIEEKEEKPL 525
Query: 511 LPTDQPVPIDLATPKHSEGKMSKAQR--------RKKNKRALKSAWSESVHHSSDQNAKT 562
++ PI+ P + K S Q+ +K + ++ +W + + K
Sbjct: 526 KLIEEEKPIESELPWRRDKKKSIEQKVTEIPIEEKKVEEEQVEVSWRKPREKVMKEVQKE 585
Query: 563 PVQRTESLKLVEAKSVK 579
V+ ++KL A+ K
Sbjct: 586 KVEDFTAIKLKPARKEK 602
Score = 37.7 bits (86), Expect = 0.94
Identities = 128/595 (21%), Positives = 226/595 (37%), Gaps = 95/595 (15%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPE----PVVVATAIPI 73
EE E + E+ +E KKK KKK+I+++G E H + + + E PV+ T
Sbjct: 3767 EEVHEQVTVAEEIKEGK-PKKKITKKKQIRQKGREQHVSETITVEEEGKLPVITIT---- 3821
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
E P E+ E E V P+ + +K+ T+ + E E + K+
Sbjct: 3822 --EGPTEEIIE--ETLKVLSAPEYAKPDELEEIRKQVTITQEMTE-EGKSKQI------- 3869
Query: 134 PTQLCSVKKKKKRKGAESNEAVAE----LATVCTEPPAVQ-----GGVLPEPKPKEPCST 184
T+ ++K+K K++ V E T+ TE P + LP + +P
Sbjct: 3870 -TKQKAIKRKGKKQQVTEIVLVEEEGKSPVTIITEGPIEEIVKETVRALPTVERVDPIKV 3928
Query: 185 EHPRVCPEPPLGLAIPIDPEKNRK--EAEPNE-------SNAEHPRACPEPPLGLAIPID 235
E V E + + + K K E EPNE N E + ++
Sbjct: 3929 E--EVVEEVTVTEIVTEEAIKYLKIEEFEPNEVQNGILSRNVEEAAILSKSKKKKVKRLE 3986
Query: 236 PEKNKGENLTPTDENELDRRNRREELV-ALVTSDEKIVNPRDHLVPLK-SIPGFVLEQQT 293
E K E L E EL + E+LV L+ EK V + + LK P +
Sbjct: 3987 KEIAKLEKLDQEFE-ELKKELPLEKLVEPLIEKPEKKVKKKKPVEKLKGEKPQLMKISIK 4045
Query: 294 QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETK 353
+ P+ P S + + + + K + K + + S +H PP K
Sbjct: 4046 EQKPIKPKFEESVTPLFAQIKLKKAPVKPKKKEDKDEIKFPKVLLRSRITEHEW-PPSIK 4104
Query: 354 KRVLDREEPNKC-NAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK 412
++ EPN N +L T+ ++A+ K K K+ K
Sbjct: 4105 YCIITELEPNYVQNGELSRTM--------EEAL--------------KLKKMKHKKVKFP 4142
Query: 413 NVLLSEGGKSNEHNGQPTETPVQK--SVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKM 470
++E K ++ + + P++K ++P ++P + K +GK
Sbjct: 4143 EKEITELEKVDQEFEKLKKIPLEKGEEIAPYERKPKSKESEEEKPKKL-----KIGKGKP 4197
Query: 471 SNAQRNNVLLSEGVKSNEQPTETP-VQKSVNPI--KAPSID--------PTLPTDQPV-P 518
+A+ E +K + P + P V + + PI K +D P +P P
Sbjct: 4198 RSAEEEE---PEIIKLKKIPEKVPSVPEKLAPIAKKKDEVDKPEKEKEEKEYPKLKPFEP 4254
Query: 519 IDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLV 573
++ T + ++ + + KK ++ K ++ + KTPVQ TE++ +V
Sbjct: 4255 YEIETTEIELEELEELEYPKKPEKVPKKMLTK----KPKKEHKTPVQETEAVPIV 4305
>UniRef100_UPI0000431AEB UPI0000431AEB UniRef100 entry
Length = 3793
Score = 72.8 bits (177), Expect = 3e-11
Identities = 134/584 (22%), Positives = 236/584 (39%), Gaps = 84/584 (14%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P P + +E+ ++ KKKK KE+ + ++V
Sbjct: 3229 QVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEV 3288
Query: 60 LLPEPV---VVATAIPITLETPKEQGAEPI------EATVVHPVPDQRPAK------THR 104
L +PV V I +E K + +P+ E T+ P P ++ + T +
Sbjct: 3289 TLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLK 3348
Query: 105 KKKKKE-TVLEPQPE----PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELA 159
KKK KE +VLE E +P PKE E T+ +KK KK+K E EA E+
Sbjct: 3349 KKKPKEKSVLEEVKEEVTLKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEIT 3404
Query: 160 TVCTEP------PAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE 211
EP ++ L + KPKE E V E L IP + PE+ ++ E
Sbjct: 3405 IKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLE--EVKEEVTLKKPIPKEKVPEEVTEQVE 3462
Query: 212 ---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSD 268
P + A E + P++ E+ + T+E L ++ +E+ V +
Sbjct: 3463 IKKPKKKKPVEEEAADEITIKKPEPVEKEEEE-----ITEEVTLKKKKPKEKPVLEEVKE 3517
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
E + +P + +P V EQ +P PV +A I + V E++I +
Sbjct: 3518 EVTLKKP---IPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPELVEKEEEEITE 3574
Query: 327 RSRMSKMKRKR---MNSMPDKHNTEPPETKKRVL----DREEPNKCNAKLPETLMLASNC 379
+ K K K + + ++ + P+ K++VL ++ E K K P A
Sbjct: 3575 DITLKKKKPKEKPVLEEVTEEITLKKPKEKEKVLEEVTEKIEVKKSKKKKPIVEEAADEV 3634
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVS 439
I + + ++ E + P++ R K K + E E + T T +
Sbjct: 3635 TIKKIVEEETK-------EEEAPEEVVLRPKSKRKSIVE---EEEEVTEVTITKPKPVEE 3684
Query: 440 PINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSV 499
+ ++ L +PV E ++++ ++ +E + E P E ++K
Sbjct: 3685 EKKSKEVEVFLKKKKPV---------VEEEVADVTVKKLISTE---AEEVPEEFTIKKKK 3732
Query: 500 NPIKAPSIDPTLPTDQPVPIDLATP--KHSEGKMSKAQRRKKNK 541
P K P++ + + P + EG++S + KK K
Sbjct: 3733 KPEKKPTVPEEVEETAITIKKVRGPEERKEEGEVSTEIQIKKKK 3776
Score = 66.2 bits (160), Expect = 2e-09
Identities = 137/607 (22%), Positives = 236/607 (38%), Gaps = 76/607 (12%)
Query: 17 REEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLE 76
+++KP+ P PE+ +E+ KK K+K +EE IE + + + V IT++
Sbjct: 2973 KKKKPKEKPIPEEIKEEITLKK--LKEKVSEEEQIEIKKPKE---KKSVEKEATSEITIK 3027
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQ 136
P E E I V +KK E V E +P PKE + SE +
Sbjct: 3028 KPVENEEEEILEEVT----------LKKKKPVLEEVKEEITLKKPIPKEKVPEEISEQIE 3077
Query: 137 LCSVKKKKKRKGAESNEA----VAELATVCTEPPAVQGGV-LPEPKPKEPCSTEHPRVCP 191
+KK KK+K E A + + TV E + V L + KPKE E V
Sbjct: 3078 ---IKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEEVTLKKKKPKEKPVLE--EVKE 3132
Query: 192 EPPLGLAIPID--PEKNRKEAE---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTP 246
E L IP + PE+ ++ E P + A E + + P+ EK + E
Sbjct: 3133 EVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADE--ITIKKPVSIEKEEEE---I 3187
Query: 247 TDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPN 304
T+E L ++ +E+ V +E + +P + +P + EQ +P PV
Sbjct: 3188 TEEVTLKKKKPKEKPVLEEVKEEVTLKKP---IPKEKVPEEITEQVEIKKPKKKKPVEEE 3244
Query: 305 SASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR---MNSMPDKHNTEPPETKKRV----L 357
+A I + P+ E++I + + K K K + + ++ + P K++V
Sbjct: 3245 AADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEVTLKKPVPKEKVPEEIT 3304
Query: 358 DREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAK------K 411
++ E K K P A I + P + E T KK K + K K
Sbjct: 3305 EQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEII--EEVTLKKKKPKEKSVLEEVK 3362
Query: 412 KNVLLSE---GGKSNEHNGQPTETPVQKSVSPINAPSIDP-TLPTDQPV---------PI 458
+ V L + K E + E K P+ + D T+ +P+ +
Sbjct: 3363 EEVTLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEV 3422
Query: 459 DLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQ------KSVNPIKAPSIDPTLP 512
L K E + + V L + + + P E Q K P++ + D +
Sbjct: 3423 TLKKKKPKEKSVLEEVKEEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAAD-EIT 3481
Query: 513 TDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKL 572
+P P++ + +E +++ +++ K K L+ E K P + TE +++
Sbjct: 3482 IKKPEPVEKEEEEITE-EVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTEQVEI 3540
Query: 573 VEAKSVK 579
+ K K
Sbjct: 3541 KKPKKKK 3547
Score = 59.7 bits (143), Expect = 2e-07
Identities = 117/565 (20%), Positives = 221/565 (38%), Gaps = 50/565 (8%)
Query: 29 QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEA 88
++ ++ + KK K+K+ EE E E + +PV A IT++ P+ E E
Sbjct: 3051 EEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEI 3110
Query: 89 TVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKG 148
T + ++P + ++ KE V +P P+ + E E T+ +KK KK+K
Sbjct: 3111 TEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPE-------EVTEQVEIKKPKKKKP 3163
Query: 149 AESNEA----VAELATVCTEPPAVQGGV-LPEPKPKEPCSTEHPRVCPEPPLGLAIPID- 202
E A + + ++ E + V L + KPKE E V E L IP +
Sbjct: 3164 VEEEAADEITIKKPVSIEKEEEEITEEVTLKKKKPKEKPVLE--EVKEEVTLKKPIPKEK 3221
Query: 203 -PEKNRKEAE---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRR 258
PE+ ++ E P + A E + PI+ E+ + +E L ++ +
Sbjct: 3222 VPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEE-----IIEEVTLKKKKPK 3276
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIP 316
E+ V +E + VP + +P + EQ +P PV +A I + P
Sbjct: 3277 EKSVLEEVKEEVTLKKP---VPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEP 3333
Query: 317 VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLA 376
+ E++I + + K K K + + + + T K+ + +E K+PE +
Sbjct: 3334 IEKEEEEIIEEVTLKKKKPKEKSVLEE---VKEEVTLKKPVPKE-------KVPEEI--- 3380
Query: 377 SNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQK 436
++ P P + T KK + K++ ++ E + + + K
Sbjct: 3381 -TEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVK 3439
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEG-KMSNAQRNNVLLSEGV-KSNEQPTETP 494
+ P +P + +++ PK + + A + E V K E+ TE
Sbjct: 3440 EEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEV 3499
Query: 495 VQKSVNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSES 551
K P + P ++ + +P+P + + +E + ++ KK K + A E
Sbjct: 3500 TLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTE--QVEIKKPKKKKPVEEEAADEI 3557
Query: 552 VHHSSDQNAKTPVQRTESLKLVEAK 576
+ K + TE + L + K
Sbjct: 3558 TIKKPELVEKEEEEITEDITLKKKK 3582
Score = 58.5 bits (140), Expect = 5e-07
Identities = 133/637 (20%), Positives = 241/637 (36%), Gaps = 100/637 (15%)
Query: 10 LHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVAT 69
+ +K +++KP PE +E K KK+ ++E+ IE E T
Sbjct: 2867 IEMEKIPKKKKPIATIEPEDKEEIIEEIKPEMKKEIVEEKEIEEKE-------------T 2913
Query: 70 AIPITLETPKEQGAEPIEATVVHP---------VPDQRPAKTHRKKKKKETVLEPQ---- 116
+TL+ P+E+ +E I + P D+ K ++KKE + Q
Sbjct: 2914 ITEVTLKKPEEKISEEIIEEIKKPEAKKPVKKETSDEITVKKSIVEEKKEEEIPEQIILK 2973
Query: 117 ---PEPEPEPKETS--------NTDHSEPTQLCSVKKKKKRKGAESNEAVAELA----TV 161
P+ +P P+E SE Q+ +KK K++K E EA +E+
Sbjct: 2974 KKKPKEKPIPEEIKEEITLKKLKEKVSEEEQI-EIKKPKEKKSVE-KEATSEITIKKPVE 3031
Query: 162 CTEPPAVQGGVLPEPKP-----KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESN 216
E ++ L + KP KE + + P + P ++ I+ +K +K+ E
Sbjct: 3032 NEEEEILEEVTLKKKKPVLEEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEA 3091
Query: 217 AEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRD 276
A+ + + P EK + E T+E L ++ +E+ V +E +
Sbjct: 3092 ADE--------ITIKKPETVEKEEEE---ITEEVTLKKKKPKEKPVLEEVKEEVTLKKP- 3139
Query: 277 HLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMK 334
+P + +P V EQ +P PV +A I + + + E++I + + K K
Sbjct: 3140 --IPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPVSIEKEEEEITEEVTLKKKK 3197
Query: 335 RKR---MNSMPDKHNTEPPETKKRV----LDREEPNKCNAKLPETLMLASNCHIDQAIPS 387
K + + ++ + P K++V ++ E K K P A I + P
Sbjct: 3198 PKEKPVLEEVKEEVTLKKPIPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPI 3257
Query: 388 DSNPAVPTNPEHKTPKKWKKRAK------KKNVLLSE---GGKSNEHNGQPTETPVQKSV 438
+ E T KK K + K K+ V L + K E + E K
Sbjct: 3258 EKEEEEII--EEVTLKKKKPKEKSVLEEVKEEVTLKKPVPKEKVPEEITEQVEIKKPKKK 3315
Query: 439 SPINAPSIDP-TLPTDQPV---------PIDLATPKHSEGKMSNAQRNNVLLSEGVKSNE 488
P+ + D T+ +P+ + L K E + + V L + V +
Sbjct: 3316 KPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEVTLKKPVPKEK 3375
Query: 489 QPTETPVQ------KSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKR 542
P E Q K P++ + D + +P PI+ + E +++ +++ K K
Sbjct: 3376 VPEEITEQVEIKKPKKKKPVEEEAAD-EITIKKPEPIEKEEEEIIE-EVTLKKKKPKEKS 3433
Query: 543 ALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVK 579
L+ E K P + TE +++ + K K
Sbjct: 3434 VLEEVKEEVTLKKPIPKEKVPEEVTEQVEIKKPKKKK 3470
Score = 52.4 bits (124), Expect = 4e-05
Identities = 121/607 (19%), Positives = 221/607 (35%), Gaps = 134/607 (22%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
+K + EEKP+ E+ K K KK++EE IE + ++L +P + +P
Sbjct: 350 EKEKFEEKPK---------EEELKPLKLEKPKKLEEEEIEEEKVTEMLWKKPEEI--PVP 398
Query: 73 ITLETPKEQGAEPIEATVVHPVPD-------QRPAKTHRKKKKKETVLEPQPEPEPEPKE 125
+ E Q + IEAT V + + ++ R++K K+ V+E E + +
Sbjct: 399 VEKEV-STQEVQVIEATKVEKIVEDVVEVEKKKVQVEDRRRKHKQQVIE---EYTTKFRR 454
Query: 126 TSNTDHSEPTQL-CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCST 184
S D + + ++ +KKK K E N V E L + KPK P S
Sbjct: 455 GSKEDETAAVKTKKTIIRKKKPKNEEDNVVVIE-------------EELEDIKPKIP-SI 500
Query: 185 EHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNK---- 240
+ P + I ++ + E E + +A P I+ K +
Sbjct: 501 PKKQFMPIEEVTTTIDVEEIIPTRIEEAEEVEQKEIKALPAQEKVKPTEIEEVKEQITVT 560
Query: 241 ------GENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQ 294
G+ T + + R + +++ +VT +E+ P E
Sbjct: 561 EDTTKLGKPKKTTKKKIIKRHGKEQKVTEVVTVEEEEKAP---------------ETTVT 605
Query: 295 PGPVIPVCPNS-ASLIGQSQTIPVVDTEQK-----INKRSRMSKMKRKRMNSMPDKHNTE 348
GPV + + SL G +P E K + +++ K K+ + + E
Sbjct: 606 EGPVEEIVEETIKSLPGLEMVVPTEVEEVKEQVTVTEEITKLGKPKKTTKKKIIKRRGKE 665
Query: 349 PPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNP------AVPT------- 395
T+ ++ E K PET + + +++ + P VPT
Sbjct: 666 QQVTEVVTVEEE------GKAPETTV--TEGPVEEIVEETIKPLPGLEKVVPTEIDQVKE 717
Query: 396 ------------NPEHKTPKKWKKRAKKKN-----VLLSEGGKSNEH--NGQPTETPVQK 436
P+ T KK KR K+ V + E GK+ E P E V++
Sbjct: 718 QVTVTEEITKLGKPKKTTKKKIVKRRGKQQQVTEVVTVEEEGKAPETTVTEGPVEEIVEE 777
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNN-----------------VL 479
++ P+ P ++ +PT+ + T K+ +++ V
Sbjct: 778 TIKPL--PGLEKVVPTEVEEVKEQVTVTEEITKLGKSKKTTKKKIIKRRGKEQQVTEVVT 835
Query: 480 LSEGVKS-----NEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKA 534
+ E K+ E P E V +++ P+ P ++ +PT+ + T K+ K
Sbjct: 836 VEEEGKAPKTTVTEGPVEEIVAETIKPL--PGLEKVVPTEVEEVKEQVTVTEEITKLGKP 893
Query: 535 QRRKKNK 541
++ K K
Sbjct: 894 KKTTKKK 900
Score = 48.9 bits (115), Expect = 4e-04
Identities = 128/599 (21%), Positives = 228/599 (37%), Gaps = 134/599 (22%)
Query: 38 KKRRKKKKIKEEGIESHEHDQVLLPE----PVVVATAIPITLETPKEQGAEPIEATVVHP 93
KK KKK IK G E + V + E P T PI E I + P
Sbjct: 1299 KKTTKKKIIKRRGKEQQVTEVVTVEEEGKAPETTVTEGPI----------EKIVEETIKP 1348
Query: 94 VPD-QRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESN 152
+P ++ A T ++ K++ + + +PK+T+ KK KR+G E
Sbjct: 1349 LPGLEKVAPTEVEEVKEQVTVTEEITKLGKPKKTTK------------KKIIKRRGKE-- 1394
Query: 153 EAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEP 212
+ V E+ TV E A + V P K T + P P L P + E+ +++
Sbjct: 1395 QQVTEVVTVEEEGKAPETTVTEGPIEKIVEET----IKPLPGLEKVAPTEVEEVKEQVTV 1450
Query: 213 NESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIV 272
E + LG P+K T + + RR + +++ +VT +E+
Sbjct: 1451 TEEITK---------LG-----KPKKT-------TKKKIIKRRGKEQQVTEVVTVEEEGK 1489
Query: 273 NPRDHLV--PLKSIPGFVLEQQTQPGPVIP-VCPNSASLIGQSQTIPVVDTEQKINKRSR 329
P+ ++ P++ I +E+ +P P + V P + + T+ ++I K +
Sbjct: 1490 APKTTVIEGPVEEI----VEETIKPLPGLEKVVPTEVEELKEQVTVT-----EEITKLGK 1540
Query: 330 MSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDS 389
K +K++ K E T+ ++ E K P+T ++ +++ +
Sbjct: 1541 PKKTTKKKIIKRRGK---EQQVTEVVTVEEE------GKAPKTTVIEGP--VEEIVEETI 1589
Query: 390 NP------AVPTNPEH------------------KTPKKW--KKRAKKKNVL----LSEG 419
P VPT E KT KK K+R K++ V + E
Sbjct: 1590 KPLPGLEKVVPTEVEELKEQVTVTEEITKLGKPKKTTKKKIIKRRGKEQQVTEVVTVEEE 1649
Query: 420 GKSNEHN--GQPTETPVQKSVSPINAPSIDPTLPTD-----QPVPID-----LATPKHSE 467
GK+ + P E V++++ P+ P ++ +PT+ + V + L PK +
Sbjct: 1650 GKAPKTTVIEGPVEEIVEETIKPL--PGLEKVVPTEVEEVKEQVTVTEEITKLGKPKKTT 1707
Query: 468 GKMSNAQRNN-------VLLSEGVKS-----NEQPTETPVQKSVNPIKAPSIDPTLPTDQ 515
K +R V + E K+ E P E V++++ P+ PT +
Sbjct: 1708 KKKIVKRRGKQQQVTEVVTVEEEGKAPETTVTEGPIEAIVEETIKPLPGLEKVPTEVEEV 1767
Query: 516 PVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVE 574
+ + EGK K ++K +R K + + ++ K PV L E
Sbjct: 1768 KEQVTVTEEVSQEGKPKKVTKKKVIRRKGKQQ-QVTEFVTIEEQGKAPVTSVTETPLEE 1825
Score = 48.5 bits (114), Expect = 5e-04
Identities = 112/552 (20%), Positives = 213/552 (38%), Gaps = 70/552 (12%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLET 77
EE+ E + E ++ KK + KKKKI EE I+ D + E +V +ET
Sbjct: 2728 EEEEEIIEIIETPMQKIIKKKSKDKKKKIVEEVIQKTIEDAKAMEERKIVE-----IIET 2782
Query: 78 PKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQL 137
P ++ + +A KT +++ E ++ +P E K+ + E T++
Sbjct: 2783 PTKKIIKKKKAIFTE-------GKT--PEEEVEEIVIEKPVNEKVQKDVVPQEGIEITEI 2833
Query: 138 ---CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPP 194
S+++ ++K V+E+ TE ++ + PK K+P +T + PE
Sbjct: 2834 IAETSIEQLPEKKLKPEESKVSEVEEEKTEITQIEMEKI--PKKKKPIAT----IEPEDK 2887
Query: 195 LGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDR 254
+ I PE ++ E E E E L PE+ E + + +
Sbjct: 2888 EEIIEEIKPEMKKEIVE--EKEIEEKETITEVTLK-----KPEEKISEEIIEEIKKPEAK 2940
Query: 255 RNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQT 314
+ ++E +T + IV + + IP ++ ++ +P P+ P +
Sbjct: 2941 KPVKKETSDEITVKKSIVEEKKE----EEIPEQIILKKKKPKEK-PI-PEEI-----KEE 2989
Query: 315 IPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDRE----EPNKCNAKLP 370
I + ++K+++ ++ K K S+ +K T KK V + E E K P
Sbjct: 2990 ITLKKLKEKVSEEEQIEIKKPKEKKSV-EKEATSEITIKKPVENEEEEILEEVTLKKKKP 3048
Query: 371 ETLMLASNCHIDQAIPSDSNP-AVPTNPEHKTPKKWKK---------RAKKKNVLLSEGG 420
+ + + IP + P + E K PKK K KK + E
Sbjct: 3049 VLEEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEAADEITIKKPETVEKEEE 3108
Query: 421 KSNEH----NGQPTETPVQKSVS---PINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNA 473
+ E +P E PV + V + P +P + +++ PK + +
Sbjct: 3109 EITEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTEQVEIKKPKKKK-PVEEE 3167
Query: 474 QRNNVLLSEGV---KSNEQPTETPVQKSVNPIKAPSIDPT---LPTDQPVPIDLATPKHS 527
+ + + + V K E+ TE K P + P ++ + +P+P + + +
Sbjct: 3168 AADEITIKKPVSIEKEEEEITEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEIT 3227
Query: 528 EGKMSKAQRRKK 539
E K ++KK
Sbjct: 3228 EQVEIKKPKKKK 3239
Score = 46.2 bits (108), Expect = 0.003
Identities = 122/598 (20%), Positives = 225/598 (37%), Gaps = 95/598 (15%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLET 77
EE E + + E E K R+K+ K EG E ++V++ E V I +E
Sbjct: 2510 EEIKEEIVTSEIMSEDGAKKTVRKKRVTKKREGKEQIT-EEVIVEEEVTEEVVEGIIIEQ 2568
Query: 78 PKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQL 137
P EQ A+PI + + + KKKK+ + E E E ET T PTQ
Sbjct: 2569 PDEQEAQPIMEELETVTITEHDVRNIPKKKKEVVIKE-----EEEIFETIET----PTQK 2619
Query: 138 CSVKK-KKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP--EPP 194
KK + +KG E E V E ++ +P+ +E E R+ E P
Sbjct: 2620 IIRKKIRPMKKGGE--EIVVE-------------EIIQKPR-EETIEMEKQRIIEVIETP 2663
Query: 195 LGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDR 254
+ + + + P E E P+ +I I+ EK K + + ++D
Sbjct: 2664 IKKVVKKIKAVVKDDGVPEEIVEEIVIEKPQKEKAKSI-IEEEKEKVKVM------KIDL 2716
Query: 255 RNRREELVALVTSDEKIV----NPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIG 310
+ ++ +V +E+I+ P ++ KS +++ VI A +
Sbjct: 2717 KQAPKKPEEIVEEEEEIIEIIETPMQKIIKKKSKD----KKKKIVEEVIQKTIEDAKAME 2772
Query: 311 QSQTIPVVDT-EQKINKRSRMSKMKRKRMNSMPDKHNTEPP---ETKKRVLDRE--EPNK 364
+ + + +++T +KI K+ + + K ++ E P + +K V+ +E E +
Sbjct: 2773 ERKIVEIIETPTKKIIKKKKAIFTEGKTPEEEVEEIVIEKPVNEKVQKDVVPQEGIEITE 2832
Query: 365 CNA-----KLPETLMLASNCHIDQA--------------IPSDSNPAVPTNPEHKTPKKW 405
A +LPE + + + IP P PE K
Sbjct: 2833 IIAETSIEQLPEKKLKPEESKVSEVEEEKTEITQIEMEKIPKKKKPIATIEPEDKEEIIE 2892
Query: 406 KKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH 465
+ + + K ++ E K E TE ++K I+ I+ + P+ T
Sbjct: 2893 EIKPEMKKEIVEE--KEIEEKETITEVTLKKPEEKISEEIIEEIKKPEAKKPVKKETSDE 2950
Query: 466 SEGKMS--NAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLAT 523
K S ++ + + + ++P E P+ + + + + +
Sbjct: 2951 ITVKKSIVEEKKEEEIPEQIILKKKKPKEKPIPEEIK--------------EEITLKKLK 2996
Query: 524 PKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVKAK 581
K SE + + ++ K+ K K A SE K PV+ E +++E ++K K
Sbjct: 2997 EKVSEEEQIEIKKPKEKKSVEKEATSEI-------TIKKPVENEEE-EILEEVTLKKK 3046
Score = 42.4 bits (98), Expect = 0.038
Identities = 129/616 (20%), Positives = 229/616 (36%), Gaps = 108/616 (17%)
Query: 7 SELLHSKKRRREEKPEP----LPSPEQDQEQ-------SCSKKKRRKKKKIKEEGIESHE 55
+E++ +++ +E+KPE +P + E + + +K++KIK++ +
Sbjct: 2406 TEIVTEEEKEQEKKPEYYLKFVPKDDDIVETVEIVTTVNMEETPEKKQRKIKKKKTTTKR 2465
Query: 56 HDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEP 115
D+ +P V+ IT+E E+G EP+ TV V D+ A + +E
Sbjct: 2466 GDE----KPKVIEE---ITIE---EEGVEPM-VTVEEIVEDKLEAVS----------IEL 2504
Query: 116 QPEPEPEPKETSNTDH--SEPTQLCSVKKKKKRKGAESNEAVAELATVCTE--PPAVQGG 171
+P P E KE T SE +V+KK+ K E E + E V E V+G
Sbjct: 2505 KPVPIEEIKEEIVTSEIMSEDGAKKTVRKKRVTKKREGKEQITEEVIVEEEVTEEVVEGI 2564
Query: 172 VLPEPKPKE--PCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLG 229
++ +P +E P E V IP K +KE E E E P
Sbjct: 2565 IIEQPDEQEAQPIMEELETVTITEHDVRNIP----KKKKEVVIKEE--EEIFETIETPTQ 2618
Query: 230 LAI--PIDPEKNKGENLTPTD-----ENELDRRNRREELVALVTSDEKIVNPRDHLVPLK 282
I I P K GE + + E ++ + + T +K+V +V
Sbjct: 2619 KIIRKKIRPMKKGGEEIVVEEIIQKPREETIEMEKQRIIEVIETPIKKVVKKIKAVVKDD 2678
Query: 283 SIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMP 342
+P ++E+ P Q + + E+K ++ ++ K+ K+ P
Sbjct: 2679 GVPEEIVEEIVIEKP-------------QKEKAKSIIEEEK--EKVKVMKIDLKQAPKKP 2723
Query: 343 DKHNTEPPE-------TKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPT 395
++ E E ++++ ++ +K + E + I+ A + V
Sbjct: 2724 EEIVEEEEEIIEIIETPMQKIIKKKSKDKKKKIVEEVIQKT----IEDAKAMEERKIVEI 2779
Query: 396 NPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQ-----PTETPVQKSVSPINAPSIDPTL 450
+TP KK KKK + +EG E + P VQK V P I +
Sbjct: 2780 ---IETPT--KKIIKKKKAIFTEGKTPEEEVEEIVIEKPVNEKVQKDVVPQEGIEITEII 2834
Query: 451 PTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTE-TPVQKSVNPIKAPSIDP 509
+ K E K+S + E+ TE T ++ P K I
Sbjct: 2835 AETSIEQLPEKKLKPEESKVSEVE-------------EEKTEITQIEMEKIPKKKKPIAT 2881
Query: 510 TLPTDQPVPIDLATPKHSEGKMSKAQRRKKN-------KRALKSAWSESVHHSSDQNAKT 562
P D+ I+ P+ + + + + +K K+ + E + AK
Sbjct: 2882 IEPEDKEEIIEEIKPEMKKEIVEEKEIEEKETITEVTLKKPEEKISEEIIEEIKKPEAKK 2941
Query: 563 PVQRTESLKLVEAKSV 578
PV++ S ++ KS+
Sbjct: 2942 PVKKETSDEITVKKSI 2957
Score = 40.0 bits (92), Expect = 0.19
Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 52/188 (27%)
Query: 13 KKRRREEKPEP--------LPSPEQDQEQSCSKKKRRKK-----------KKIKEEGIES 53
K++ EEKPE LP E+++E K +++K K IK+E E
Sbjct: 21 KEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEE 80
Query: 54 HEHDQVLLP---------EPVVVATAIPITLETPKEQGAEPI---------------EAT 89
+ ++V L E V T P+ E P+E+ E + E
Sbjct: 81 EKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVV 140
Query: 90 VVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGA 149
+ P+ ++P ++K +E L+P PE +PKE + E +L + K K
Sbjct: 141 TLKPIKKEKP----EEEKPEEVKLKPVKRPE-KPKE----EKPEEVKLKPIPKSVSEKVE 191
Query: 150 ESNEAVAE 157
E E AE
Sbjct: 192 EKPEDEAE 199
>UniRef100_UPI000023F701 UPI000023F701 UniRef100 entry
Length = 4221
Score = 71.2 bits (173), Expect = 8e-11
Identities = 128/574 (22%), Positives = 206/574 (35%), Gaps = 104/574 (18%)
Query: 18 EEKP--EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI---- 71
E KP EP P+ E +EQ + ++ + EE + E V P+PV +
Sbjct: 438 ESKPAEEPAPTEEPKEEQ-----RTVEEPEPSEEQASAEEPTPVEEPKPVEEPSPSEEPE 492
Query: 72 ----PITLET--PKEQGAEPIE-ATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPK 124
P + E P E+ A E A P P + PA T K + EP P EP P
Sbjct: 493 PSKEPASTEELKPTEEPAPAEEPAPAEEPAPAEEPASTEELKPTE----EPAPAEEPAPA 548
Query: 125 ETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKP-KEPCS 183
E EP + ++ + ++ +++ E A P + G L +PK +EP S
Sbjct: 549 E-------EPAPADEPELVEEPEPSKESKSTEESAPADGSTPVEESGPLEDPKTVEEPAS 601
Query: 184 TEHPRVCPE-PPLGLAIP-IDPEKNRKEAEPNESNAEHPRACPEP-PLGLAIPIDP---- 236
TE P E G + P +PE + ES A EP P G P++
Sbjct: 602 TEEPAPAAETASAGESKPNEEPEPTEQPTLVEESKEVEESAPEEPKPSGDPAPVEELTPN 661
Query: 237 EKNKGENLTPTDENELDRRNRREE--LVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQ 294
E+ K + + DEN + E +V DE NP D + P P E
Sbjct: 662 EEPKMKEPSTQDENAAEEPKTESEASVVGKSGKDEPETNPTDEVSPAPEGPAPTKESDPA 721
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKK 354
P+ +S T+P + ++ K T+ PE
Sbjct: 722 DEPLA-----EDKQTEESSTVPAAEEVSS---------------EALGAKDETKEPEA-- 759
Query: 355 RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNV 414
A+ PET A++ +Q P+D A + + P + +K + + V
Sbjct: 760 ------------AQEPET---AADLKSEQDKPADVGEAATS----EAPSEPEKAPENEAV 800
Query: 415 LLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQ 474
E K++EH + + K AP+ T++P D A
Sbjct: 801 ATLEEEKTSEHGNENSSQSDNKPEPADEAPA-----ATEEPPDKDTAGEPE--------- 846
Query: 475 RNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKA 534
S+ V ++E P TP + +N D + +P + P + +++
Sbjct: 847 ------SKPVANDEMPL-TPDEAPLNDKTVGKSDEAEQSSEP---EKTEPSDKDAQVTMP 896
Query: 535 QRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTE 568
K+ K A S + +D +PV+ E
Sbjct: 897 TEDNKDAEDEKPAVSTETQNYTDSEESSPVEEAE 930
Score = 62.8 bits (151), Expect = 3e-08
Identities = 121/571 (21%), Positives = 199/571 (34%), Gaps = 71/571 (12%)
Query: 21 PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKE 80
P P QD+ + S K++ KK S D LPEP + P T E KE
Sbjct: 86 PPPQEPSAQDEPSASSSSKKKSKK--------SKRKDSKSLPEPPSIPIPPPPTAEASKE 137
Query: 81 QGAEPIEATVVHP----VPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNT-----DH 131
E +EA P D K + K E P PE PKE +T D
Sbjct: 138 --PEKVEAKTDEPETAGTQDNADTKDVSATEDK-AAGEETPTPEAVPKEDESTKDTKDDE 194
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
++ + VK+ ++EA E+ V E PA + + P E + E P
Sbjct: 195 ADKEEEPPVKEDAPPDETPTSEAGEEVTLV--EVPAQEDSTEQDAAPDEKPTEEAP---- 248
Query: 192 EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENE 251
P E + K + + + + P E P G EK + E
Sbjct: 249 ----AAETPATEETSTK--DDDATAVQEPTTPSEAPTGEESLPKDEKATESEVVDAQEKG 302
Query: 252 LDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQ 311
D + + A S K + K +++ + +
Sbjct: 303 SDGDDDEPSMAAESKSTSKSQKTKKKEKEKKEKEKKEKKEKEE----------------K 346
Query: 312 SQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNA--KL 369
+ +E+ + +S+ S K + S DK PP K D++E A K+
Sbjct: 347 DKKKAASKSEKSHHHKSKYSHSSSKEVGSSKDKALDPPPVAK----DKQEAVTVPAEPKV 402
Query: 370 PETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQP 429
ET S S P + + +TP + K A E E +
Sbjct: 403 EETKASESEAESQPVEKSLLPSEEPASSKEETPTEESKPA--------EEPAPTEEPKEE 454
Query: 430 TETPVQKSVSPINAPSIDPTLPTDQPVPIDLATP-KHSEGKMSNAQRNNVLLSEGVKSNE 488
T + S A + +PT P ++P P++ +P + E A + +E E
Sbjct: 455 QRTVEEPEPSEEQASAEEPT-PVEEPKPVEEPSPSEEPEPSKEPASTEELKPTEEPAPAE 513
Query: 489 QPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAW 548
+P P ++ + S + PT++P P + P + + ++ + S
Sbjct: 514 EP--APAEEPAPAEEPASTEELKPTEEPAPAEEPAPAEEPAPADEPELVEEPE---PSKE 568
Query: 549 SESVHHSSDQNAKTPVQRTESLKLVEAKSVK 579
S+S S+ + TPV+ ES L + K+V+
Sbjct: 569 SKSTEESAPADGSTPVE--ESGPLEDPKTVE 597
Score = 61.2 bits (147), Expect = 8e-08
Identities = 122/575 (21%), Positives = 201/575 (34%), Gaps = 75/575 (13%)
Query: 2 DSHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRK-KKKIKEEGIESHEHDQVL 60
D S SK + +K + ++++E+ K+K K KKK + +SH H
Sbjct: 306 DDDEPSMAAESKSTSKSQKTKKKEKEKKEKEKKEKKEKEEKDKKKAASKSEKSHHHKS-- 363
Query: 61 LPEPVVVATAIPITLETPKEQGAEPIEATVVHPVP-DQRPAKTHRKKKKKETVLEPQPEP 119
+ + KE G+ +A PV D++ A T + K E + E
Sbjct: 364 -----------KYSHSSSKEVGSSKDKALDPPPVAKDKQEAVTVPAEPKVEETKASESEA 412
Query: 120 EPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKP- 178
E +P E S EP K+ E ++ E A TE P + + EP+P
Sbjct: 413 ESQPVEKSLLPSEEPAS------SKEETPTEESKPAEEPAP--TEEPKEEQRTVEEPEPS 464
Query: 179 KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNA--------EHPRACPEP-PLG 229
+E S E P EP P++ +E EP++ A E P EP P
Sbjct: 465 EEQASAEEPTPVEEPK-----PVEEPSPSEEPEPSKEPASTEELKPTEEPAPAEEPAPAE 519
Query: 230 LAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVL 289
P + E E L PT+E E A E + P P K
Sbjct: 520 EPAPAE-EPASTEELKPTEEPAPAEEPAPAEEPAPADEPELVEEPE----PSKESKS--- 571
Query: 290 EQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEP 349
+++ P S L TE+ S + K N EP
Sbjct: 572 TEESAPADGSTPVEESGPLEDPKTVEEPASTEEPAPAAETAS--------AGESKPNEEP 623
Query: 350 PETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRA 409
T++ L E + E +++ P++ P+ K P + A
Sbjct: 624 EPTEQPTLVEESKEVEESAPEEPKPSGDPAPVEELTPNE-------EPKMKEPSTQDENA 676
Query: 410 KKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPID--LATPKHSE 467
++ SE + ET VSP AP + PT + P D LA K +E
Sbjct: 677 AEEPKTESEASVVGKSGKDEPETNPTDEVSP--AP--EGPAPTKESDPADEPLAEDKQTE 732
Query: 468 GKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHS 527
+ S + SE + + ++ E + P L ++Q P D+ S
Sbjct: 733 -ESSTVPAAEEVSSEALGAKDETKEPEAAQE------PETAADLKSEQDKPADVGEAATS 785
Query: 528 EGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKT 562
E S+ ++ +N+ ++ H ++ ++++
Sbjct: 786 EAP-SEPEKAPENEAVATLEEEKTSEHGNENSSQS 819
Score = 59.7 bits (143), Expect = 2e-07
Identities = 121/572 (21%), Positives = 200/572 (34%), Gaps = 90/572 (15%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPV---VVATAIPIT 74
E EP +PE + + +++K E G E+ PEP AT P
Sbjct: 786 EAPSEPEKAPENEAVATL------EEEKTSEHGNENSSQSDNK-PEPADEAPAATEEPPD 838
Query: 75 LETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEP-EPEPKE-------- 125
+T E ++P+ + PD+ P K E +PE EP K+
Sbjct: 839 KDTAGEPESKPVANDEMPLTPDEAPLNDKTVGKSDEAEQSSEPEKTEPSDKDAQVTMPTE 898
Query: 126 -------------TSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGV 172
T ++++ + V++ +K A + E A + PA +
Sbjct: 899 DNKDAEDEKPAVSTETQNYTDSEESSPVEEAEKNDDATAAPPEKESAEDANDIPAEKEAP 958
Query: 173 LPE-------------------PKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPN 213
+P+ P + P P + A K +K+ + +
Sbjct: 959 IPDAVHSKAGKAASDKTAVEQVPITEAPKEEAPPTEAAQAEDATASASKKTKKKKKKKGS 1018
Query: 214 ESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVN 273
+S E P EP + +PID K + P E E+ E V+ S+E
Sbjct: 1019 KSGIEIP-VTAEPAV---VPIDEAAVK-VMMEPMIEPEVPVEPTTEPEVSEKASNEPTSE 1073
Query: 274 PRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQK-INKRSRMSK 332
P+ P P E T P PN ++ + +T VD+E K + + +
Sbjct: 1074 PKTAAKPEADNP--TTESATGPEAAEKALPNESTTEQEPET--TVDSESKSVTGPATEPE 1129
Query: 333 MKRKRMNSMPDKHNTEPPET---KKRVLDREEPNKCN--------------AKLPETLML 375
K + S+ + + PET + V+D E P + A PET+
Sbjct: 1130 ATEKAIESVAEPEDAAKPETVVKPETVIDSEAPTESEVVETAVEPTAEPEIAPEPETV-- 1187
Query: 376 ASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGG---KSNEHNGQPTET 432
ID PSD + A T PE K +K + + + +S++ QPT
Sbjct: 1188 -----IDSEAPSDESAAEAT-PEPKVVEKAIEPVSESEAAVENEAARPESDDSVVQPTTE 1241
Query: 433 PVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTE 492
P ++ P+++P L T + + E + A + L K+ EQ E
Sbjct: 1242 PEVAEKVAVDEPALEPELETAAEAKASVDSKPAVEPAVEPAVEPSTELEVAEKAAEQDYE 1301
Query: 493 TPVQKSVNPIKAPSIDPTLPTDQPVPIDLATP 524
V + + PS T +DQP A P
Sbjct: 1302 PEVVEKAASDELPSALET-ASDQPATDPSAEP 1332
Score = 58.2 bits (139), Expect = 7e-07
Identities = 121/596 (20%), Positives = 213/596 (35%), Gaps = 110/596 (18%)
Query: 5 SQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKE---------------- 48
++SE++ ++++ + + + + S S+K ++K+K+ KE
Sbjct: 291 TESEVVDAQEKGSDGDDDEPSMAAESKSTSKSQKTKKKEKEKKEKEKKEKKEKEEKDKKK 350
Query: 49 ---EGIESHEH----------------DQVLLPEPV-------VVATAIPITLET---PK 79
+ +SH H D+ L P PV V A P ET
Sbjct: 351 AASKSEKSHHHKSKYSHSSSKEVGSSKDKALDPPPVAKDKQEAVTVPAEPKVEETKASES 410
Query: 80 EQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNT-DHSEPTQLC 138
E ++P+E ++ +P + PA + + +E+ +P P EPKE T + EP++
Sbjct: 411 EAESQPVEKSL---LPSEEPASSKEETPTEESKPAEEPAPTEEPKEEQRTVEEPEPSE-- 465
Query: 139 SVKKKKKRKGAESNEAVAELATVCTEP-PAVQGGVLPEPKP-KEPCSTEHPRVCPEP--- 193
+A AE T EP P + EP+P KEP STE + EP
Sbjct: 466 -------------EQASAEEPTPVEEPKPVEEPSPSEEPEPSKEPASTEELKPTEEPAPA 512
Query: 194 ----PLGLAIPIDPEKNRKEAEPNE--SNAEHPRACPEPPLGLAIPIDPEKNKGENLTPT 247
P P + + +E +P E + AE P EP P D E E P+
Sbjct: 513 EEPAPAEEPAPAEEPASTEELKPTEEPAPAEEPAPAEEP-----APAD-EPELVEEPEPS 566
Query: 248 DENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSAS 307
E++ + + V + +P+ P + +P P S
Sbjct: 567 KESKSTEESAPADGSTPVEESGPLEDPKTVEEPAST---------EEPAPAAETASAGES 617
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNA 367
+ T + +K S + + + P P + ++ + ++ A
Sbjct: 618 KPNEEPEPTEQPTLVEESKEVEESAPEEPKPSGDPAPVEELTPNEEPKMKEPSTQDENAA 677
Query: 368 KLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWK------------KRAKKKNVL 415
+ P+T AS ++NP +P + P K K+ ++ + +
Sbjct: 678 EEPKTESEASVVGKSGKDEPETNPTDEVSPAPEGPAPTKESDPADEPLAEDKQTEESSTV 737
Query: 416 LSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSE--GKMSNA 473
+ S+E G ET K P L ++Q P D+ SE + A
Sbjct: 738 PAAEEVSSEALGAKDET---KEPEAAQEPETAADLKSEQDKPADVGEAATSEAPSEPEKA 794
Query: 474 QRNNVLLS-EGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSE 528
N + + E K++E E Q P P+ + T++P D A S+
Sbjct: 795 PENEAVATLEEEKTSEHGNENSSQSDNKP--EPADEAPAATEEPPDKDTAGEPESK 848
Score = 49.7 bits (117), Expect = 2e-04
Identities = 114/568 (20%), Positives = 209/568 (36%), Gaps = 79/568 (13%)
Query: 18 EEKP--EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITL 75
+ KP EP P + ++ ++ + E +E D+ LP + A+ P T
Sbjct: 1270 DSKPAVEPAVEPAVEPSTELEVAEKAAEQDYEPEVVEKAASDE--LPSALETASDQPAT- 1326
Query: 76 ETPKEQGAEPIEATVVHPVPDQRPA--------KTHRKKKKKETVLEPQP---------- 117
+ AEP V+ P D +P K ++ E + E +P
Sbjct: 1327 ----DPSAEPTAEPVLKPADDSKPGTEPEVDLNKPASEQALDEPLAELKPAADTEAAEKV 1382
Query: 118 ---EPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEP----PAV-- 168
EP P P+ S+ +PT + K+ ++ + + + EP PA+
Sbjct: 1383 ASDEPSPAPETASDQPAVKPTAVEPETDPDKQASEQARDESSTEIKLAAEPEVDEPAIET 1442
Query: 169 --QGGVLPEPKPKEPCSTEHPRVCP----EPPLGLAIPIDPEKNRKEAEPNESNAEHPRA 222
+ EP P +++ P P P P + + +E E +
Sbjct: 1443 TAEKAASDEPSPTPETASDQPATEPAVKSAPESESVSDKPPAVESESSTKSEPTVESVKE 1502
Query: 223 CPE--------PPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVT-SDEKIVN 273
PE P + +P D ++ E DE+E + + E V + E++ N
Sbjct: 1503 TPEVVKTESGVEPEQVVVPKDDVSSEDE-----DESEFESESESESGVEPDNGAPEEVAN 1557
Query: 274 PRD-HLVPLKSIPGFVLEQQTQ-PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMS 331
+D +S+ G E+ T V P + +++ P ++K + + +
Sbjct: 1558 NKDIDNSDTESLEGKSTERATSADSEVDSAKPTIREMSNEAKEEP-SPLKKKEDSQEASA 1616
Query: 332 KMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNP 391
+ + + P+ ++ E E K + ++ N A + E+ + + D+ DS+
Sbjct: 1617 ETEAPASSVEPENNDVEVSEPKAAATEGKD-NTVVANMSESEATSESEDEDEDEDDDSDS 1675
Query: 392 A-VPTNPEHKTPKKWKKRAKKKNVLLS----EGGKSNEHNGQPTETPVQKSVSPINAPSI 446
P + T K A+++ L + K ++ + TE+ +K P +P
Sbjct: 1676 EHQPAESDKATDALPAKIAEEEPALAEKDTLDSAKEDDSDSPITESTDEKKDKP--SPPE 1733
Query: 447 DPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPS 506
P + P ATP H E + S V L++ V E E+ V+KS +P P
Sbjct: 1734 TPAEKANAP-----ATPSHEEAEDST---ETVELADTVDKKE--PESAVEKSDSPQVKP- 1782
Query: 507 IDPTLPTDQPVPIDLATPKHSEGKMSKA 534
+ T ID A SE S+A
Sbjct: 1783 -ESTAQEGAAAEIDPADDDTSEDSASEA 1809
Score = 48.5 bits (114), Expect = 5e-04
Identities = 129/597 (21%), Positives = 198/597 (32%), Gaps = 99/597 (16%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVL----------------L 61
EE EP+ S D+E S K+K +E I E Q + L
Sbjct: 1911 EETQEPVASGADDKEPEESPLISTKEKAALDEPIAEEEAKQPIDDATGHDEKPETESPPL 1970
Query: 62 PEPVVVATAI---PITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPE 118
+P A+ + P +Q AE +E D+ PA +K+ET +P P
Sbjct: 1971 DKPANDEPALDDKDLGATRPAQQTAEDVE-MCDEDSADEAPA----VDEKQETPGDPVPS 2025
Query: 119 PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLP-EPK 177
E ++T+ + L K + A + A A T + + V +P
Sbjct: 2026 KPEEVEDTTLEEKPVVETLADDKDIQDAAEASDEDQTAPEAAPSTSEKSEEILVADVDPG 2085
Query: 178 PKEPCSTEHPRVCP-EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP 236
E S E + G A P D + AE +++ ++ P P G +
Sbjct: 2086 ESEAPSAEPDGAAEVDDKHGGATPPDGVLEQTVAEVSDNESDTPAPAPATEDGES----K 2141
Query: 237 EKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDH-------LVPLKSIPGFVL 289
EK+K PT E E A E V P D V L P V
Sbjct: 2142 EKDKTAEQEPTIEPPATDEKPEETAQASNDEPEPPVAPSDEPKEAETPEVALAEKPTVVG 2201
Query: 290 E-------QQTQPGPVIPVCPNSASLIGQSQTIPVVD---TEQKINKRSRMSKMKRKRMN 339
+ + +P +PV N +++ PV + +E+K+ + + ++ + +
Sbjct: 2202 DDSKEAEVSEAEPVVEVPVQDNPPEAEAEAEVEPVKEASVSEEKLAEEEQTAQAQEEPQQ 2261
Query: 340 SMPDKHNTEPPETKKRVLDR--EEPNKCNAKLPETLMLASNCHIDQAIPSDS-NPAVPTN 396
NT P E +K D E P + K E + A I D N + PT
Sbjct: 2262 GSAPADNT-PEEEEKSAKDEHIEAPTTSDDKAGEDVKSAEEPPASAPIAEDELNQSPPTA 2320
Query: 397 PEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTE-TPVQKSVSPINAPSIDPTLPTDQP 455
+ E K + TE TPV + VS P T+ TD
Sbjct: 2321 AQ-------------------EESKETTTAEETTEATPVAEPVSASEEPPAGDTVSTDDK 2361
Query: 456 VPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQ 515
D PK++E + A VQ+ +P P T
Sbjct: 2362 AVDD---PKNAEDVATPA---------------------VQEPCSPEGEGESKPVDETPA 2397
Query: 516 PVPIDLAT-PKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKT---PVQRTE 568
P P D P A+ KK +K+ E D+ +K P+ RT+
Sbjct: 2398 PEPEDATVKPIDDSADAPPAEAEKKEDEPVKATTKEDTRAKEDEESKDTLGPIPRTK 2454
Score = 38.1 bits (87), Expect = 0.72
Identities = 100/500 (20%), Positives = 190/500 (38%), Gaps = 36/500 (7%)
Query: 48 EEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKK 107
E+G ES E D+ EP + P T E P+E +A+ P P P+ ++ +
Sbjct: 2136 EDG-ESKEKDKTAEQEPTIEP---PATDEKPEETA----QASNDEPEPPVAPSDEPKEAE 2187
Query: 108 KKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPA 167
E L +P + + + +EP V+ AE+ + A+V E A
Sbjct: 2188 TPEVALAEKPTVVGDDSKEAEVSEAEPVVEVPVQDNPPEAEAEAEVEPVKEASVSEEKLA 2247
Query: 168 VQ---GGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACP 224
+ EP+ + P + I + K E +S E P + P
Sbjct: 2248 EEEQTAQAQEEPQQGSAPADNTPEEEEKSAKDEHIEAPTTSDDKAGEDVKSAEEPPASAP 2307
Query: 225 --EPPLGLAIPIDPEKNKGENLTPTDENE----LDRRNRREELVA--LVTSDEKIV---- 272
E L + P ++ E T + E + + EE A V++D+K V
Sbjct: 2308 IAEDELNQSPPTAAQEESKETTTAEETTEATPVAEPVSASEEPPAGDTVSTDDKAVDDPK 2367
Query: 273 NPRDHLVPLKSIP-GFVLEQQTQPGPVIPVC-PNSASL--IGQSQTIPVVDTEQKINKRS 328
N D P P E +++P P P A++ I S P + E+K ++
Sbjct: 2368 NAEDVATPAVQEPCSPEGEGESKPVDETPAPEPEDATVKPIDDSADAPPAEAEKKEDEPV 2427
Query: 329 RMSKMKRKRMNSMPDKHNT--EPPETKKRVLDREEPNKC-NAKLPETLMLASNCHIDQAI 385
+ + + R + +T P TKK V EE N ++ +D+ +
Sbjct: 2428 KATTKEDTRAKEDEESKDTLGPIPRTKKPVKKGEENGSLQNTPFDFAQNYGNSTELDKNM 2487
Query: 386 PSDSNPAVPTNPEHKTPKK-WKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAP 444
+ ++ + + + + ++ +++ ++ K+ L S+++N T +Q ++A
Sbjct: 2488 DNGASELLSEDTQELSERQHYEESSELKSRSLMTEAPSDQNNQTATGITMQGLQETLSAV 2547
Query: 445 SIDP-TLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIK 503
DP + + +DL + S+ S+ +N +EQ T + + I
Sbjct: 2548 DEDPQDRVVSKTLDLDL---QDSDLVTSHPATSNTREPTPGTPHEQGTPDQSEDAAKEID 2604
Query: 504 APSIDPTLPTDQPVPIDLAT 523
++D ++ T P P+ T
Sbjct: 2605 PVNVD-SIATATPQPLQPET 2623
Score = 36.6 bits (83), Expect = 2.1
Identities = 104/495 (21%), Positives = 166/495 (33%), Gaps = 58/495 (11%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETP 78
++PEP +P D+ + + +K G +S E + V EPVV E
Sbjct: 2171 DEPEPPVAPS-DEPKEAETPEVALAEKPTVVGDDSKEAE-VSEAEPVVEVPVQDNPPEAE 2228
Query: 79 KEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLC 138
E EP++ V +T + +++ + P E ++++ +H E
Sbjct: 2229 AEAEVEPVKEASVSEEKLAEEEQTAQAQEEPQQGSAPADNTPEEEEKSAKDEHIEAPTTS 2288
Query: 139 SVKKKKKRKGAESNEAVAELA--TVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP----- 191
K + K AE A A +A + PP E E + P P
Sbjct: 2289 DDKAGEDVKSAEEPPASAPIAEDELNQSPPTAAQEESKETTTAEETTEATPVAEPVSASE 2348
Query: 192 EPPLGLAI-----PIDPEKNRKEA------EP------NESNAEHPRACPEPPLGLAIPI 234
EPP G + +D KN ++ EP ES PEP PI
Sbjct: 2349 EPPAGDTVSTDDKAVDDPKNAEDVATPAVQEPCSPEGEGESKPVDETPAPEPEDATVKPI 2408
Query: 235 DPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQ 294
D + E+E + +E+ A + K D L P+ V ++ +
Sbjct: 2409 DDSADAPPAEAEKKEDEPVKATTKEDTRAKEDEESK-----DTLGPIPRTKKPV-KKGEE 2462
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDK-HNTEPPETK 353
G + + A G S TE N + S++ + + ++ H E E K
Sbjct: 2463 NGSLQNTPFDFAQNYGNS-------TELDKNMDNGASELLSEDTQELSERQHYEESSELK 2515
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKN 413
R L E P+ N + + + A+ D V K + +
Sbjct: 2516 SRSLMTEAPSDQNNQTATGITMQGLQETLSAVDEDPQDRV-------VSKTLDLDLQDSD 2568
Query: 414 VLLSEGGKSNEHN---GQPTE--TPVQ-----KSVSPINAPSIDPTLPTD-QPVPIDLAT 462
++ S SN G P E TP Q K + P+N SI P QP + T
Sbjct: 2569 LVTSHPATSNTREPTPGTPHEQGTPDQSEDAAKEIDPVNVDSIATATPQPLQPETTETLT 2628
Query: 463 PKHSEGKMSNAQRNN 477
+ N N
Sbjct: 2629 EEPDSEPSYNTHDGN 2643
Score = 35.8 bits (81), Expect = 3.6
Identities = 99/542 (18%), Positives = 189/542 (34%), Gaps = 100/542 (18%)
Query: 5 SQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEP 64
S + +E+P PL E QE S + + +E +D
Sbjct: 1586 SAKPTIREMSNEAKEEPSPLKKKEDSQEASA-------ETEAPASSVEPENND------- 1631
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPK 124
+ + PK E + TVV + E E + E E E
Sbjct: 1632 --------VEVSEPKAAATEGKDNTVV------------ANMSESEATSESEDEDEDE-D 1670
Query: 125 ETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATV------CTEPPAVQGGVLPEPKP 178
+ S+++H +P + K AE A+AE T+ ++ P + + KP
Sbjct: 1671 DDSDSEH-QPAESDKATDALPAKIAEEEPALAEKDTLDSAKEDDSDSPITESTDEKKDKP 1729
Query: 179 KEPCSTEHPRVCPEPP-----------LGLAIPIDPEKNRKEAEPNESNAEHPRACPEPP 227
P + P P + LA +D +KE E ++ P+ PE
Sbjct: 1730 SPPETPAEKANAPATPSHEEAEDSTETVELADTVD----KKEPESAVEKSDSPQVKPEST 1785
Query: 228 L--GLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIP 285
G A IDP D+ D + + + + +K+++ +P+
Sbjct: 1786 AQEGAAAEIDP---------ADDDTSEDSASEASDDDTIASLTDKVIDGEAPRLPVNPED 1836
Query: 286 GFVLEQQTQPGP-VIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDK 344
L+ +T P + +A + + V++ E + + + MPD
Sbjct: 1837 DSPLDGKTSHAPDTLDTDEANAQVSSEDSKGSVIEAEDAVQEPLDGGAQDK----PMPDN 1892
Query: 345 HNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKK 404
+ PE+ D+ P+ + E + + D P +S P + T + +
Sbjct: 1893 EAPKEPESN----DKNSPHTDAEETQEPVASGA----DDKEPEES-PLISTKEKAALDEP 1943
Query: 405 WKKRAKKKNVLLSEGGKSNEHNGQP-TETPVQKSVSPINAPSIDPTLPTDQPVPIDLATP 463
+ K+ + + G H+ +P TE+P P++ P+ D D+ DL
Sbjct: 1944 IAEEEAKQPIDDATG-----HDEKPETESP------PLDKPANDEPALDDK----DLGAT 1988
Query: 464 KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLAT 523
+ ++ + + + ++ + ++ ETP P K ++ T ++PV LA
Sbjct: 1989 RPAQQTAEDVEMCDEDSADEAPAVDEKQETPGDPV--PSKPEEVEDTTLEEKPVVETLAD 2046
Query: 524 PK 525
K
Sbjct: 2047 DK 2048
Score = 35.4 bits (80), Expect = 4.7
Identities = 52/239 (21%), Positives = 83/239 (33%), Gaps = 72/239 (30%)
Query: 3 SHSQSELLHSKKRRREE---KPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
+H + + S++R REE + EP + QE++ +++R ++ K KE E
Sbjct: 3970 THDRRKAERSERRTREENERRREPTRYHQSRQEENDKERERERRSKGKEPARE------- 4022
Query: 60 LLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEP 119
PEP EP P P+ + HR+ +++ P+ E
Sbjct: 4023 --PEP-----------------EREPFPEIEPQPEPE---VERHRRSRRQSHSGRPRHE- 4059
Query: 120 EPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVL------ 173
+H + + S +KK A+++E V + T PP + V
Sbjct: 4060 ----------EHRDRAREESASPEKKLFTAKNSERVLD----ATPPPREEAPVAEPVRER 4105
Query: 174 -----PEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPP 227
PE PK ST H R +E P S PEPP
Sbjct: 4106 TRDAPPEDSPKR-SSTRHRR-------------STHPTAEEPRPRSSRVRRDDTVPEPP 4150
>UniRef100_Q96QC2 KIAA0170 protein [Homo sapiens]
Length = 2090
Score = 70.9 bits (172), Expect = 1e-10
Identities = 132/621 (21%), Positives = 217/621 (34%), Gaps = 132/621 (21%)
Query: 4 HSQSELLHSK-----KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQ 58
H + LL+ K K R E + +Q+ +C + ++ + S
Sbjct: 1002 HQKGSLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKH 1061
Query: 59 VLLPEPVV--VATAIPITLETPKEQGAEPI-------EATVVHPVPDQRPAKTHRKKKKK 109
L P P++ + +I T+ ++ G++ E HP P R K+ R
Sbjct: 1062 -LAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP 1120
Query: 110 ETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ 169
T P+P P T+ +PT + + + R ++ E V V T P
Sbjct: 1121 ATSAAPEPHPS---TSTAQPVTPKPTSQ-ATRSRTNRSSVKTPEPV-----VPTAPELQP 1171
Query: 170 GGVLPEPKPKEPCS-------TEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRA 222
+P EP S + PE + A+ + P + +E ++ R
Sbjct: 1172 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRG 1231
Query: 223 --------CPEPPLGLAIPIDPEKNKGENLT--PTDENELDRRNRREELVALVTSDEKIV 272
PEP + A + P + + +T PT + R+NR + V + E +V
Sbjct: 1232 RKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR-----SSVKTPEPVV 1286
Query: 273 NPRDHLVPLKSIPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVV 318
L P S V + T P V+P P Q +
Sbjct: 1287 PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPK 1346
Query: 319 DTEQKINKRSRMSKMKRKRMN-----SMPDKHNTEPPETKKRV--LDREEPNKCNAKLPE 371
T + R+ MS +K +P +TE P T + R N+ + K PE
Sbjct: 1347 PTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPE 1406
Query: 372 TLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTE 431
TL VPT P+ + + + + G++N + + E
Sbjct: 1407 TL-------------------VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPE 1447
Query: 432 TPVQKSVSPINAPSIDPTLPTDQPVPIDLATPK-HSEGKMSNAQRNNVLLSEGV------ 484
T V AP + P+ TDQPV TP+ S+ R++V E V
Sbjct: 1448 TVVP------TAPELQPSTSTDQPV-----TPEPTSQATRGRTDRSSVKTPETVVPTAPE 1496
Query: 485 ----KSNEQP-TETPVQKSVNPIK--------------APSIDPTLPTDQPVPIDLATPK 525
S +QP T P ++ K AP + P TDQPV TP+
Sbjct: 1497 LQASASTDQPVTSDPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDQPV-----TPE 1551
Query: 526 HSEGKMSKAQRRKKNKRALKS 546
+ S+A R + N+ ++K+
Sbjct: 1552 PT----SRATRGRTNRSSVKT 1568
Score = 59.7 bits (143), Expect = 2e-07
Identities = 134/650 (20%), Positives = 232/650 (35%), Gaps = 112/650 (17%)
Query: 3 SHSQSELLHSKKRRREEK-PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
S S++ +K R K PE + + + S S + + + V
Sbjct: 1181 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT 1240
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP--EP 119
PEPVV TA + T +Q PV + + R +K + +V P+P
Sbjct: 1241 PEPVV-PTAPELQPSTSTDQ-----------PVTSEPTYQATRGRKNRSSVKTPEPVVPT 1288
Query: 120 EPEPKETSNTDHS---EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
PE + +++TD +PT + + + ++ E V A + V P+P
Sbjct: 1289 APELRPSTSTDRPVTPKPTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1347
Query: 177 KPKEP------CSTEHPR----VCPEPPLGLAI--PIDPEKNRKEAEPNESNAEHPRACP 224
+ S ++P + PE P + P+ PE + ++ + P
Sbjct: 1348 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKT--P 1405
Query: 225 EPPLGLAIPIDPEKNKGENLTPTDENELDR-RNRREELVALVTSDEKIVNPRDHLVPLKS 283
E + A ++P + + +TP ++ R R R V + E +V L P S
Sbjct: 1406 ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSS----VKTPETVVPTAPELQPSTS 1461
Query: 284 IPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSR 329
V + T P V+P P + Q + T + R
Sbjct: 1462 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSDPTSRTTRGRKN 1521
Query: 330 MSKMKRKRMNSMPDKHNTEPPETKKRVLDRE--------EPNKCNAKLPETLM------- 374
S +K +P +PP + + + E N+ + K PE+++
Sbjct: 1522 RSSVKTPE-TVVPAAPELQPPTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQ 1580
Query: 375 ---------------LASNCHIDQAIPSDSNPAVPTNPE-HKTPKKWKKRAKKKNVLLSE 418
A+ C +++ P VPT PE H T + K L+
Sbjct: 1581 PSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPK----LTS 1636
Query: 419 GGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH-SEGKMSNAQRNN 477
+ N +TP K V P A ++P PTDQ V TP+ ++G S R++
Sbjct: 1637 RATRRKTNRSSVKTP--KPVEPA-ASDLEPFTPTDQSV-----TPEAIAQGGQSKTLRSS 1688
Query: 478 VLLSEGVKSN---EQPTETPVQKSVNPIKAPSIDPTL-----PTDQPVPIDLATPKHSEG 529
+ + V + + P T S PI PS P PID K
Sbjct: 1689 TVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPID---HKPCSA 1745
Query: 530 KMSKAQRRKKNKR--ALKSAWSESV--HHSSDQNAKTPVQRTESLKLVEA 575
+ + +N+R A+++A S + +S Q +TP+ ++ K+ A
Sbjct: 1746 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPA 1795
>UniRef100_Q20626 Hypothetical protein F49E2.5a [Caenorhabditis elegans]
Length = 1215
Score = 70.5 bits (171), Expect = 1e-10
Identities = 116/534 (21%), Positives = 197/534 (36%), Gaps = 71/534 (13%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKK------RRKKKKIKEEGIESHEHDQ- 58
Q + + K+ ++K + + + + EQ + KK RR + + K+ + EH Q
Sbjct: 63 QPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKAAEKEARRAEAEAKKRAAQEEEHKQW 122
Query: 59 ------VLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPD-QRPAKTHRKKKKKET 111
+ + A + E KE+ + +A PA + K+
Sbjct: 123 KAEQERIQKEQEKKEADLKKLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVKKV 182
Query: 112 VLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGG 171
+ P PEPK +NT Q+ + KK +K + +E+ A A P +V+
Sbjct: 183 ANDRSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAA-----PASVEQV 237
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLA 231
V E P+V E P A P +KN+K +ES E+ A E P+
Sbjct: 238 V------------EQPKVVTEEPHQQAAP-QEKKNKKNKRKSES--ENVPAASETPVEPV 282
Query: 232 IPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHL-----VPLKSIPG 286
+ P ++ + D+ + + EE V K D++ V K P
Sbjct: 283 VETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFVTAKEEPK 342
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN 346
+T PV V N + + T P +K NK+ + K + +++ P +
Sbjct: 343 DE-PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDK-KKSESEKVTEQPVESA 400
Query: 347 TEPP------ETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNP--------- 391
PP ET + ++ NK + K E+ QA PS P
Sbjct: 401 PAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVE--EPVQAAPSSKKPTADDSMDFL 458
Query: 392 ----AVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSV-SPIN-APS 445
A P E P + K + + SE K N+ + + +E+ +K+V P+ AP+
Sbjct: 459 DFVTAKPDRSEVAAPVEVAK-VDESTAVTSENRKKNKKDKKKSES--EKAVEEPVQAAPT 515
Query: 446 IDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSV 499
D +D T K E ++ + E + NE P PV K +
Sbjct: 516 SKKPTADDSMDFLDFVTAK--EERVEEVAPVQEQVKE--QKNESPESEPVAKLI 565
Score = 68.2 bits (165), Expect = 7e-10
Identities = 129/584 (22%), Positives = 212/584 (36%), Gaps = 146/584 (25%)
Query: 18 EEKPEPLPSPE-QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLE 76
+++ E S E +Q Q K K+ +KKK +++ + HE +Q + + A E
Sbjct: 49 DQRKEAFASLELTEQPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKAAEKEARRAEAE 108
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQ 136
K E H + ++++KKE L+ + + E + ++ + +E
Sbjct: 109 AKKRAAQEE-----EHKQWKAEQERIQKEQEKKEADLK-KLQAEKKKEKAVKAEKAE--- 159
Query: 137 LCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLG 196
K +K K A + V E + + A P P+PK P +T P P
Sbjct: 160 -----KAEKTKKASTPAPVEE--EIVVKKVANDRSAAPAPEPKTPTNT------PAEPAE 206
Query: 197 LAIPIDPEKNRKEAEPNESNA-----------EHPRACPEPPLGLAIPIDPEKNKGENLT 245
I +KN+K + +ES A E P+ E P A P + +KNK
Sbjct: 207 QVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKVVTEEPHQQAAPQE-KKNKKNKRK 265
Query: 246 PTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNS 305
EN VP S +T PV+
Sbjct: 266 SESEN----------------------------VPAAS--------ETPVEPVV------ 283
Query: 306 ASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLD------- 358
+T P QK NK+ K K + + + E P++KK D
Sbjct: 284 -------ETTPPASENQKKNKKD---KKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLD 333
Query: 359 ----REEPNKCNAKLPETLM--LASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKK 412
+EEP A+ P + + N ++ + + P P K KK KK+++ +
Sbjct: 334 FVTAKEEPKDEPAETPAAPVEEVVENV-VENVVEKSTTP--PATENKKKNKKDKKKSESE 390
Query: 413 NVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSN 472
V TE PV+ + +P P ++ + T TP SE K N
Sbjct: 391 KV---------------TEQPVESAPAP---PQVEQVVET---------TPPASENKKKN 423
Query: 473 AQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLP-----TDQPVPIDLATP--- 524
+ + +E+ E PVQ + + K P+ D ++ T +P ++A P
Sbjct: 424 KK------DKKKSESEKAVEEPVQAAPSS-KKPTADDSMDFLDFVTAKPDRSEVAAPVEV 476
Query: 525 -KHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRT 567
K E ++ RKKNK+ K + SE Q A T + T
Sbjct: 477 AKVDESTAVTSENRKKNKKDKKKSESEKAVEEPVQAAPTSKKPT 520
Score = 50.4 bits (119), Expect = 1e-04
Identities = 103/524 (19%), Positives = 196/524 (36%), Gaps = 98/524 (18%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP 62
S S++ + + E+P+ + Q KK ++ K+K + E
Sbjct: 223 SESEATAAPASVEQVVEQPKVVTEEPHQQAAPQEKKNKKNKRKSESEN------------ 270
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPE-P 121
+P ETP EP+ T +Q+ K +KK + E V+E + E P
Sbjct: 271 --------VPAASETP----VEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAP 318
Query: 122 EPKETSNTDHSEPTQLCSVKKKKKRKGAESNEA---------VAELATVCTEPPAVQGGV 172
+ K+ + D+ + + K++ K + AE+ A V + T PPA +
Sbjct: 319 KSKKPTADDNMDFLDFVTAKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKK 378
Query: 173 LPEPKPKEPCS---TEHP-RVCPEPP-LGLAIPIDP--EKNRKEAEPNESNAEHPRACPE 225
+ K+ S TE P P PP + + P +N+K+ + ++ +E +A E
Sbjct: 379 KNKKDKKKSESEKVTEQPVESAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEE 438
Query: 226 PPLGLAIPIDPEKNKGENLTPTDENELD------RRNRREELVA-----------LVTSD 268
P + P K PT ++ +D + R E+ A VTS+
Sbjct: 439 P-----VQAAPSSKK-----PTADDSMDFLDFVTAKPDRSEVAAPVEVAKVDESTAVTSE 488
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQTQPGPVI--PVCPNSASLIGQSQTIPVVDTEQKINK 326
+ N +D KS +E+ Q P P +S + V E+++ +
Sbjct: 489 NRKKNKKD---KKKSESEKAVEEPVQAAPTSKKPTADDSMDFLDF-----VTAKEERVEE 540
Query: 327 RSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIP 386
+ + + +++ N P+ P K + E + N ++ D+ I
Sbjct: 541 VAPVQEQVKEQKNESPESE----PVAKLITVSNTEASAVNVMGFSDIVTPK---ADEVIT 593
Query: 387 SDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSI 446
D A + P+ ++ V +S+ ++ + TP ++ S AP+
Sbjct: 594 QDPVSA----KQEVLPEHVPSEIPEEPVAVSKKPTADSMDFLDFVTPKTEAESTSEAPAP 649
Query: 447 DPTLPTDQPVPIDLATPKH---------SEGKMSNAQRNNVLLS 481
+ PT+ +++ T +H S + S N+VLL+
Sbjct: 650 VVSKPTESIEDLEIVTYEHVADVTGNTLSPSQHSTPSPNSVLLN 693
Score = 43.9 bits (102), Expect = 0.013
Identities = 114/567 (20%), Positives = 185/567 (32%), Gaps = 102/567 (17%)
Query: 16 RREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVL-LPEPVV-------- 66
++E PE +PS ++ + SKK + E + P PVV
Sbjct: 600 KQEVLPEHVPSEIPEEPVAVSKKPTADSMDFLDFVTPKTEAESTSEAPAPVVSKPTESIE 659
Query: 67 ---------VATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP 117
VA TL + P + P K H KK KK T E
Sbjct: 660 DLEIVTYEHVADVTGNTLSPSQHSTPSPNSVLLNGPQSKSSKRKHHHKKNKKRTDSEMSQ 719
Query: 118 EPEPEPKETSNTDHSEPTQL-CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
EP E E HSEP ++ V K+ A+ N + T E + P
Sbjct: 720 EPSKEDLEFLEFLHSEPKKVEKPVAPVSKKPTADDNMDFLDFVTAKPEKTESVEEHIEAP 779
Query: 177 KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP 236
EP E+ A +KN+K S +E A EP + I
Sbjct: 780 MIVEPVHAENETA--------AAAGGKKKNKKNKNKKNSESESTPAA-EPVKEVTPEIVE 830
Query: 237 EKNKGENLTP-----------TDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIP 285
E + + +TP + +N+ +++N E P+K +
Sbjct: 831 EVFEKKTITPSTAAAAAPAPGSKKNKKNKKNSESESAPAAE-------------PVKEVT 877
Query: 286 GFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKH 345
++E+ + V P +A+ S K NK K K+ + + + H
Sbjct: 878 PEIVEEVFEKKTVTPSTEAAAAPASAS----------KKNK-------KNKKGSGISESH 920
Query: 346 NTEP------PETK---KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTN 396
+T P P+T K ++ N +A S +D +P + T
Sbjct: 921 DTAPAPTVEIPQTTEGGKGSPGSDKENSGSAVNGSAKKQMSVEELDYGVPGQT---TDTT 977
Query: 397 PEHKTPKKWKKRAKKKNVLLSEGGK-----SNEHNGQPTETPVQKSVSPINAPSIDPTLP 451
+ K KK KK K + +SE + +H Q + VQ + S
Sbjct: 978 TDKKNKKKNKK--GKNSNSISENAQVIAHLEQDHLDQMADDEVQAITGAAGSHS------ 1029
Query: 452 TDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTL 511
PI + SE + ++N + ++T QK+V + + TL
Sbjct: 1030 ----PPIQVHEVTSSEQHSNGVEKNTTIEITQAVDGTDMSQTQFQKNVEKL----VQATL 1081
Query: 512 PTDQPVPIDLATPKHSEGKMSKAQRRK 538
V ID + ++ K +K
Sbjct: 1082 AKHDIVEIDPTVKLRIDAQLIKLSEKK 1108
>UniRef100_Q5ST83 Mediator of DNA damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 70.1 bits (170), Expect = 2e-10
Identities = 124/553 (22%), Positives = 196/553 (35%), Gaps = 121/553 (21%)
Query: 60 LLP--EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP 117
LLP +P V T + E P+ + +E HP P R K+ R T P+P
Sbjct: 1070 LLPSIKPTVRKTRQDGSQEAPEAPLSSELEP--FHPKPKIRTRKSSRMTPFPATSAAPEP 1127
Query: 118 EPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPK 177
P T+ +PT + + + R ++ E V V T P +P
Sbjct: 1128 HPS---TSTAQPVTPKPTSQ-ATRSRTNRSSVKTPEPV-----VPTAPELQPSTSTDQPV 1178
Query: 178 PKEPCS-------TEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRA-------- 222
EP S + PE + A+ + P + +E ++ R
Sbjct: 1179 TSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVK 1238
Query: 223 CPEPPLGLAIPIDPEKNKGENLT--PTDENELDRRNRREELVALVTSDEKIVNPRDHLVP 280
PEP + A + P + + +T PT + R+NR + V + E +V L P
Sbjct: 1239 TPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR-----SSVKTPEPVVPTAPELRP 1293
Query: 281 LKSIPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
S V + T P V+P P Q + T +
Sbjct: 1294 STSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRS 1353
Query: 327 RSRMSKMKRKRMN-----SMPDKHNTEPPETKKRV--LDREEPNKCNAKLPETLMLASNC 379
R+ MS +K +P +TE P T + R N+ + K PETL
Sbjct: 1354 RTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETL------ 1407
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVS 439
VPT P+ + + + + G++N + + ET V
Sbjct: 1408 -------------VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVP---- 1450
Query: 440 PINAPSIDPTLPTDQPVPIDLATPK-HSEGKMSNAQRNNVLLSEGV----------KSNE 488
AP + P+ TDQPV TP+ S+ R++V E V S +
Sbjct: 1451 --TAPELQPSTSTDQPV-----TPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTD 1503
Query: 489 QP-TETPVQKSVNPIK--------------APSIDPTLPTDQPVPIDLATPKHSEGKMSK 533
QP T P ++ K AP + P+ TDQPV TP+ + S+
Sbjct: 1504 QPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPV-----TPEPT----SR 1554
Query: 534 AQRRKKNKRALKS 546
A R + N+ ++K+
Sbjct: 1555 ATRGRTNRSSVKT 1567
Score = 60.1 bits (144), Expect = 2e-07
Identities = 136/650 (20%), Positives = 230/650 (34%), Gaps = 112/650 (17%)
Query: 3 SHSQSELLHSKKRRREEK-PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
S S++ +K R K PE + + + S S + + + V
Sbjct: 1180 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT 1239
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP--EP 119
PEPVV TA + T +Q PV + + R +K + +V P+P
Sbjct: 1240 PEPVV-PTAPELQPSTSTDQ-----------PVTSEPTYQATRGRKNRSSVKTPEPVVPT 1287
Query: 120 EPEPKETSNTDHS---EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
PE + +++TD +PT + + + ++ E V A + V P+P
Sbjct: 1288 APELRPSTSTDRPVTPKPTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1346
Query: 177 KPKEP------CSTEHPR----VCPEPPLGLAI--PIDPEKNRKEAEPNESNAEHPRACP 224
+ S ++P + PE P + P+ PE + ++ + P
Sbjct: 1347 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKT--P 1404
Query: 225 EPPLGLAIPIDPEKNKGENLTPTDENELDR-RNRREELVALVTSDEKIVNPRDHLVPLKS 283
E + A ++P + + +TP ++ R R R V + E +V L P S
Sbjct: 1405 ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSS----VKTPETVVPTAPELQPSTS 1460
Query: 284 IPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSR 329
V + T P V+P P + Q + T + R
Sbjct: 1461 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKN 1520
Query: 330 MSKMKRKRM------NSMPDKHNTEP--PETKKRVLDREEPNKCNAKLPETLM------- 374
S +K P +P PE R R N+ + K PE+++
Sbjct: 1521 RSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKTPESIVPIAPELQ 1579
Query: 375 ---------------LASNCHIDQAIPSDSNPAVPTNPE-HKTPKKWKKRAKKKNVLLSE 418
A+ C +++ P VPT PE H T + K L+
Sbjct: 1580 PSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPK----LTS 1635
Query: 419 GGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH-SEGKMSNAQRNN 477
+ N +TP K V P A ++P PTDQ V TP+ ++G S R++
Sbjct: 1636 RATRRKTNRSSVKTP--KPVEPA-ASDLEPFTPTDQSV-----TPEAIAQGGQSKTLRSS 1687
Query: 478 VLLSEGVKSN---EQPTETPVQKSVNPIKAPSIDPTL-----PTDQPVPIDLATPKHSEG 529
+ + V + + P T S PI PS P PID K
Sbjct: 1688 TVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPID---HKPCSA 1744
Query: 530 KMSKAQRRKKNKR--ALKSAWSESV--HHSSDQNAKTPVQRTESLKLVEA 575
+ + +N+R A+++A S + +S Q +TP+ ++ K+ A
Sbjct: 1745 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPA 1794
>UniRef100_Q86Z06 Homologue to Drosophila photoreceptor protein calphotin [Homo
sapiens]
Length = 2089
Score = 70.1 bits (170), Expect = 2e-10
Identities = 124/553 (22%), Positives = 196/553 (35%), Gaps = 121/553 (21%)
Query: 60 LLP--EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP 117
LLP +P V T + E P+ + +E HP P R K+ R T P+P
Sbjct: 1070 LLPSIKPTVRKTRQDGSQEAPEAPLSSELEP--FHPKPKIRTRKSSRMTPFPATSAAPEP 1127
Query: 118 EPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPK 177
P T+ +PT + + + R ++ E V V T P +P
Sbjct: 1128 HPS---TSTAQPVTPKPTSQ-ATRSRTNRSSVKTPEPV-----VPTAPELQPSTSTDQPV 1178
Query: 178 PKEPCS-------TEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRA-------- 222
EP S + PE + A+ + P + +E ++ R
Sbjct: 1179 TSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVK 1238
Query: 223 CPEPPLGLAIPIDPEKNKGENLT--PTDENELDRRNRREELVALVTSDEKIVNPRDHLVP 280
PEP + A + P + + +T PT + R+NR + V + E +V L P
Sbjct: 1239 TPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR-----SSVKTPEPVVPTAPELRP 1293
Query: 281 LKSIPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
S V + T P V+P P Q + T +
Sbjct: 1294 STSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRS 1353
Query: 327 RSRMSKMKRKRMN-----SMPDKHNTEPPETKKRV--LDREEPNKCNAKLPETLMLASNC 379
R+ MS +K +P +TE P T + R N+ + K PETL
Sbjct: 1354 RTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETL------ 1407
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVS 439
VPT P+ + + + + G++N + + ET V
Sbjct: 1408 -------------VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVP---- 1450
Query: 440 PINAPSIDPTLPTDQPVPIDLATPK-HSEGKMSNAQRNNVLLSEGV----------KSNE 488
AP + P+ TDQPV TP+ S+ R++V E V S +
Sbjct: 1451 --TAPELQPSTSTDQPV-----TPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTD 1503
Query: 489 QP-TETPVQKSVNPIK--------------APSIDPTLPTDQPVPIDLATPKHSEGKMSK 533
QP T P ++ K AP + P+ TDQPV TP+ + S+
Sbjct: 1504 QPVTSDPTSRTTRGRKNRSSVKTPETVVPTAPELQPSTSTDQPV-----TPEPT----SR 1554
Query: 534 AQRRKKNKRALKS 546
A R + N+ ++K+
Sbjct: 1555 ATRGRTNRSSVKT 1567
Score = 59.7 bits (143), Expect = 2e-07
Identities = 136/650 (20%), Positives = 230/650 (34%), Gaps = 112/650 (17%)
Query: 3 SHSQSELLHSKKRRREEK-PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
S S++ +K R K PE + + + S S + + + V
Sbjct: 1180 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT 1239
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP--EP 119
PEPVV TA + T +Q PV + + R +K + +V P+P
Sbjct: 1240 PEPVV-PTAPELQPSTSTDQ-----------PVTSEPTYQATRGRKNRSSVKTPEPVVPT 1287
Query: 120 EPEPKETSNTDHS---EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
PE + +++TD +PT + + + ++ E V A + V P+P
Sbjct: 1288 APELRPSTSTDRPVTPKPTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1346
Query: 177 KPKEP------CSTEHPR----VCPEPPLGLAI--PIDPEKNRKEAEPNESNAEHPRACP 224
+ S ++P + PE P + P+ PE + ++ + P
Sbjct: 1347 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKT--P 1404
Query: 225 EPPLGLAIPIDPEKNKGENLTPTDENELDR-RNRREELVALVTSDEKIVNPRDHLVPLKS 283
E + A ++P + + +TP ++ R R R V + E +V L P S
Sbjct: 1405 ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSS----VKTPETVVPTAPELQPSTS 1460
Query: 284 IPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSR 329
V + T P V+P P + Q + T + R
Sbjct: 1461 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSDPTSRTTRGRKN 1520
Query: 330 MSKMKRKRM------NSMPDKHNTEP--PETKKRVLDREEPNKCNAKLPETLM------- 374
S +K P +P PE R R N+ + K PE+++
Sbjct: 1521 RSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKTPESIVPIAPELQ 1579
Query: 375 ---------------LASNCHIDQAIPSDSNPAVPTNPE-HKTPKKWKKRAKKKNVLLSE 418
A+ C +++ P VPT PE H T + K L+
Sbjct: 1580 PSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPK----LTS 1635
Query: 419 GGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH-SEGKMSNAQRNN 477
+ N +TP K V P A ++P PTDQ V TP+ ++G S R++
Sbjct: 1636 RATRRKTNRSSVKTP--KPVEPA-ASDLEPFTPTDQSV-----TPEAIAQGGQSKTLRSS 1687
Query: 478 VLLSEGVKSN---EQPTETPVQKSVNPIKAPSIDPTL-----PTDQPVPIDLATPKHSEG 529
+ + V + + P T S PI PS P PID K
Sbjct: 1688 TVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPID---HKPCSA 1744
Query: 530 KMSKAQRRKKNKR--ALKSAWSESV--HHSSDQNAKTPVQRTESLKLVEA 575
+ + +N+R A+++A S + +S Q +TP+ ++ K+ A
Sbjct: 1745 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPA 1794
>UniRef100_Q92954 Megakaryocyte stimulating factor [Homo sapiens]
Length = 1404
Score = 69.3 bits (168), Expect = 3e-10
Identities = 122/528 (23%), Positives = 173/528 (32%), Gaps = 47/528 (8%)
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP 121
P P P T + P EP P + PA T KK T EP P
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPA------PTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 122 EP-----KETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
EP KE S T EP + K E + A + P+ P P
Sbjct: 505 EPAPTTTKEPSPTTPKEPAP--TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 177 -KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEP----PLGLA 231
PKEP T + P P A P P KE P + P A EP P A
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPA-PTTP----KEPAPTTTKKPAPTAPKEPAPTTPKETA 617
Query: 232 IPIDPEK---NKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRD--HLVPLKSIPG 286
P P+K E L PT E EEL + P + P + P
Sbjct: 618 -PTTPKKLTPTTPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 675
Query: 287 FVLE-QQTQPGPVIPVCPNSASLIGQSQTIPVV--DTEQKINKRSRMSKMKRKRMNSMPD 343
E T P P P + +T P T K + K+ +
Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 344 KHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPK 403
EP T D+ P P T + + P+ PT + P
Sbjct: 736 TTTKEPTSTTS---DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 404 KWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATP 463
KK A K+ + G ++ + +P T K +P PT P +P P TP
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKPAPTTPETP 850
Query: 464 KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLAT 523
+ ++S E ++ P E+ + S P P P + VP T
Sbjct: 851 PPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVP-TTKT 903
Query: 524 PKHSEGKMSKAQRRKKNKRALKSA--WSESVHHSSDQNAKTPVQRTES 569
P ++ +M+ + K +R L++ + + + + A T + TES
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Score = 51.2 bits (121), Expect = 8e-05
Identities = 105/473 (22%), Positives = 148/473 (31%), Gaps = 40/473 (8%)
Query: 72 PITLETPKEQGAEPIEATVVH-PVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTD 130
P T+++ EP T P + PA T K+ T EP P EP T T
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT--TT 425
Query: 131 HSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVC 190
S PT +K A + E A + P P P KEP T
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 191 PEPPLGLAIPIDPEK----NRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTP 246
P P A P P++ KE P + P EP P + P
Sbjct: 484 PTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEP 537
Query: 247 TDENELDRRNRREELVALVTSDEKIVNPRD--HLVPLKSIPGFVLEQQTQPGPVIPVCPN 304
+E T + P++ P K P +P P P P
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPA 593
Query: 305 SASLIGQSQTIP--VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEP 362
+ + T P T K + K+ + +P T L P
Sbjct: 594 PTTTKKPAPTAPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 363 NKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKS 422
+ PE + P + P P P TPK+ K+ + G +
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 423 NEHNGQPTETPVQKSVSPINAPSI--DPTLPT-DQPVPIDLATPKHSEGKMSNAQRNNVL 479
+P T +K AP+ +PT T D+P P TPK G +
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTSDKPAP---TTPK---GTAPTTPKE--- 764
Query: 480 LSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMS 532
E TP + +K P+ PT P +P P +LA P ++G S
Sbjct: 765 -PAPTTPKEPAPTTPKGTAPTTLKEPA--PTTP-KKPAPKELA-PTTTKGPTS 812
Score = 50.4 bits (119), Expect = 1e-04
Identities = 114/593 (19%), Positives = 182/593 (30%), Gaps = 49/593 (8%)
Query: 2 DSHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
+ HS SE S + + S + ++ +KK K+K+ + + +
Sbjct: 156 EEHSVSENQESSSSSSSSSSSSTIWKIKSSKNSAANRELQKKLKVKDN--KKNRTKKKPT 213
Query: 62 PEPVVVATA------------IPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKK 109
P+P VV A P T T + + + T P+ + RP+ K
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI-NPRPSLPPNSDTSK 272
Query: 110 ETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ 169
ET L E E KET+ T+ T K+K A+ +++ + + P +
Sbjct: 273 ETSLTVNKETTVETKETTTTNKQTSTD-----GKEKTTSAKETQSIEKTSAKDLAPTS-- 325
Query: 170 GGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPL- 228
VL +P PK +T+ P + P +P + EP + + P+ P
Sbjct: 326 -KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK-EPTPTTIKSAPTTPKEPAP 383
Query: 229 -----GLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKS 283
P +P + PT E +E S P K
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 284 IPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMP- 342
P T P P P + + P + +K + P
Sbjct: 444 AP-------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496
Query: 343 DKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQA-IPSDSNPAVPTNPEHKT 401
+ T P E P P T A + A + S P P P T
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 402 PKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLA 461
K+ K+ + + +P T K +P PT P +P P
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTAP-KEPAP---T 611
Query: 462 TPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDL 521
TPK + + E+P T + + P PT P ++P P
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTP-EEPAP--- 666
Query: 522 ATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVE 574
TPK + K K + E + + A T + T L E
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
>UniRef100_UPI0000431AED UPI0000431AED UniRef100 entry
Length = 1124
Score = 68.9 bits (167), Expect = 4e-10
Identities = 145/628 (23%), Positives = 248/628 (39%), Gaps = 83/628 (13%)
Query: 7 SELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVV 66
S+ + KK EEK E E+ EQ KKK+ K+K I EE + + L
Sbjct: 488 SDEITVKKSIVEEKKE-----EEIPEQIILKKKKPKEKPIPEE----IKEEITLKKLKEK 538
Query: 67 VATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKK-------KKKETVLEPQPE- 118
V+ I ++ PKE+ + EAT + ++P + ++ KKK+ VLE E
Sbjct: 539 VSEEEQIEIKKPKEKKSVEKEAT--SEITIKKPVENEEEEILEEVTLKKKKPVLEEVKEE 596
Query: 119 ---PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEA----VAELATVCTEPPAVQGG 171
+P PKE + SE + +KK KK+K E A + + TV E +
Sbjct: 597 ITLKKPIPKEKVPEEISEQIE---IKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEE 653
Query: 172 V-LPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE---PNESNAEHPRACPE 225
V L + KPKE E V E L IP + PE+ ++ E P + A E
Sbjct: 654 VTLKKKKPKEKPVLE--EVKEEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADE 711
Query: 226 PPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIP 285
+ + P+ EK + E T+E L ++ +E+ V +E + +P + +P
Sbjct: 712 --ITIKKPVSIEKEEEE---ITEEVTLKKKKPKEKPVLEEVKEEVTLKKP---IPKEKVP 763
Query: 286 GFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR---MNS 340
+ EQ +P PV +A I + P+ E++I + + K K K +
Sbjct: 764 EEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEE 823
Query: 341 MPDKHNTEPPETKKRV----LDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTN 396
+ ++ + P K++V ++ E K K P A I + P +
Sbjct: 824 VKEEVTLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEII- 882
Query: 397 PEHKTPKKWKKRAK------KKNVLLSE---GGKSNEHNGQPTETPVQKSVSPINAPSID 447
E T KK K + K K+ V L + K E + E K P+ + D
Sbjct: 883 -EEVTLKKKKPKEKSVLEEVKEEVTLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAAD 941
Query: 448 P-TLPTDQPV---------PIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQ- 496
T+ +P+ + L K E + + V L + + + P E Q
Sbjct: 942 EITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEVTLKKPIPKEKVPEEVTEQV 1001
Query: 497 -----KSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSES 551
K P++ + D + +P P++ + +E +++ +++ K K L+ E
Sbjct: 1002 EIKKPKKKKPVEEEAAD-EITIKKPEPVEKEEEEITE-EVTLKKKKPKEKPVLEEVKEEV 1059
Query: 552 VHHSSDQNAKTPVQRTESLKLVEAKSVK 579
K P + TE +++ + K K
Sbjct: 1060 TLKKPIPKEKVPEEVTEQVEIKKPKKKK 1087
Score = 62.8 bits (151), Expect = 3e-08
Identities = 107/456 (23%), Positives = 184/456 (39%), Gaps = 64/456 (14%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P + +E+ +++ KKKK KE+ + ++V
Sbjct: 615 QIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEEVTLKKKKPKEKPVLEEVKEEV 674
Query: 60 LLPEPV---VVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTH------------- 103
L +P+ V + +E K + +P+E + ++P
Sbjct: 675 TLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPVSIEKEEEEITEEVTLK 734
Query: 104 RKKKKKETVLEPQPE----PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELA 159
+KK K++ VLE E +P PKE E T+ +KK KK+K E EA E+
Sbjct: 735 KKKPKEKPVLEEVKEEVTLKKPIPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEIT 790
Query: 160 TVCTEP------PAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE 211
EP ++ L + KPKE E V E L +P + PE+ ++ E
Sbjct: 791 IKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLE--EVKEEVTLKKPVPKEKVPEEITEQVE 848
Query: 212 ---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSD 268
P + A E + PI+ E+ + +E L ++ +E+ V +
Sbjct: 849 IKKPKKKKPVEEEAADEITIKKPEPIEKEEEE-----IIEEVTLKKKKPKEKSVLEEVKE 903
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
E + VP + +P + EQ +P PV +A I + P+ E++I +
Sbjct: 904 EVTLKKP---VPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIE 960
Query: 327 RSRMSKMKRKR---MNSMPDKHNTEPPETKKR----VLDREEPNKCNAKLPETLMLASNC 379
+ K K K + + ++ + P K++ V ++ E K K P A
Sbjct: 961 EVTLKKKKPKEKSVLEEVKEEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEI 1020
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVL 415
I + P + T E T K KK+ K+K VL
Sbjct: 1021 TIKKPEPVEKEEEEIT--EEVTLK--KKKPKEKPVL 1052
Score = 62.4 bits (150), Expect = 4e-08
Identities = 96/370 (25%), Positives = 156/370 (41%), Gaps = 53/370 (14%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P P + +E+ ++ KKKK KE+ + ++V
Sbjct: 769 QVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEV 828
Query: 60 LLPEPV---VVATAIPITLETPKEQGAEPI------EATVVHPVPDQRPAK------THR 104
L +PV V I +E K + +P+ E T+ P P ++ + T +
Sbjct: 829 TLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLK 888
Query: 105 KKKKKE-TVLEPQPE----PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELA 159
KKK KE +VLE E +P PKE E T+ +KK KK+K E EA E+
Sbjct: 889 KKKPKEKSVLEEVKEEVTLKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEIT 944
Query: 160 TVCTEP------PAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE 211
EP ++ L + KPKE E V E L IP + PE+ ++ E
Sbjct: 945 IKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLE--EVKEEVTLKKPIPKEKVPEEVTEQVE 1002
Query: 212 ---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSD 268
P + A E + P++ E+ + T+E L ++ +E+ V +
Sbjct: 1003 IKKPKKKKPVEEEAADEITIKKPEPVEKEEEE-----ITEEVTLKKKKPKEKPVLEEVKE 1057
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
E + +P + +P V EQ +P PV +A I + V E++I +
Sbjct: 1058 EVTLKKP---IPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPELVEKEEEEITE 1114
Query: 327 RSRMSKMKRK 336
+ K K K
Sbjct: 1115 DITLKKKKPK 1124
Score = 59.7 bits (143), Expect = 2e-07
Identities = 117/565 (20%), Positives = 221/565 (38%), Gaps = 50/565 (8%)
Query: 29 QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEA 88
++ ++ + KK K+K+ EE E E + +PV A IT++ P+ E E
Sbjct: 591 EEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEI 650
Query: 89 TVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKG 148
T + ++P + ++ KE V +P P+ + E E T+ +KK KK+K
Sbjct: 651 TEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPE-------EVTEQVEIKKPKKKKP 703
Query: 149 AESNEA----VAELATVCTEPPAVQGGV-LPEPKPKEPCSTEHPRVCPEPPLGLAIPID- 202
E A + + ++ E + V L + KPKE E V E L IP +
Sbjct: 704 VEEEAADEITIKKPVSIEKEEEEITEEVTLKKKKPKEKPVLE--EVKEEVTLKKPIPKEK 761
Query: 203 -PEKNRKEAE---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRR 258
PE+ ++ E P + A E + PI+ E+ + +E L ++ +
Sbjct: 762 VPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEE-----IIEEVTLKKKKPK 816
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIP 316
E+ V +E + VP + +P + EQ +P PV +A I + P
Sbjct: 817 EKSVLEEVKEEVTLKKP---VPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEP 873
Query: 317 VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLA 376
+ E++I + + K K K + + + + T K+ + +E K+PE +
Sbjct: 874 IEKEEEEIIEEVTLKKKKPKEKSVLEE---VKEEVTLKKPVPKE-------KVPEEI--- 920
Query: 377 SNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQK 436
++ P P + T KK + K++ ++ E + + + K
Sbjct: 921 -TEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVK 979
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEG-KMSNAQRNNVLLSEGV-KSNEQPTETP 494
+ P +P + +++ PK + + A + E V K E+ TE
Sbjct: 980 EEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEV 1039
Query: 495 VQKSVNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSES 551
K P + P ++ + +P+P + + +E + ++ KK K + A E
Sbjct: 1040 TLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTE--QVEIKKPKKKKPVEEEAADEI 1097
Query: 552 VHHSSDQNAKTPVQRTESLKLVEAK 576
+ K + TE + L + K
Sbjct: 1098 TIKKPELVEKEEEEITEDITLKKKK 1122
Score = 39.3 bits (90), Expect = 0.32
Identities = 96/506 (18%), Positives = 181/506 (34%), Gaps = 75/506 (14%)
Query: 76 ETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPT 135
E P+E+ E ++ +P K K+++++ V+ +P + +P+E + E
Sbjct: 193 EKPEEEKPEEVKL---------KPVKRLPKEEEEKEVVTLKPIKKEKPEE----EKPEEV 239
Query: 136 QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPL 195
+L VK+ K E + V L + E P E KP+E R+ E
Sbjct: 240 KLKPVKRLPKE---EEEKEVVTLKPIKKEKPE-------EEKPEEVKLKPVKRLPKEEEE 289
Query: 196 GLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRR 255
+ + P K K P E E + P L P + E+ + L P + + +
Sbjct: 290 KEVVTLKPIKKEK---PEEEKPEEVKLKPVQRL----PKEEEEKEEVILKPIKKEKPEEE 342
Query: 256 NRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTI 315
E + V EK + V LK + E++ + V+ + P
Sbjct: 343 KPEEVKLKPVKRPEKPKEEKPEEVKLKPVKHLPKEEEEKE--VVTLKPI----------- 389
Query: 316 PVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLML 375
K+ + + K + + P K +P E + + ++EP K ++PE +
Sbjct: 390 ----------KKEKPEEEKPEEVKLKPVKQEKKPKEVIEEITLKKEPEKSMEQVPEIFIK 439
Query: 376 ASNCHIDQAIPSDSNPAVP-TNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPV 434
+ ++ V PE K ++ + KK K E V
Sbjct: 440 KPVVEEKEIEEKETITEVTLKKPEEKISEEIIEEIKKPE------AKKPVKKETSDEITV 493
Query: 435 QKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETP 494
+KS+ ++ + P I L K E + + + L K E+ +E
Sbjct: 494 KKSI-------VEEKKEEEIPEQIILKKKKPKEKPIPEEIKEEITLK---KLKEKVSE-- 541
Query: 495 VQKSVNPIKAPSIDPTLPTDQPVPIDLATP-KHSEGKMSKAQRRKKNKRALKSAWSESVH 553
+ IK P ++ + I + P ++ E ++ + KK K L+ E
Sbjct: 542 --EEQIEIKKPKEKKSVEKEATSEITIKKPVENEEEEILEEVTLKKKKPVLEEVKEEITL 599
Query: 554 HSSDQNAKTPVQRTESLKLVEAKSVK 579
K P + +E +++ + K K
Sbjct: 600 KKPIPKEKVPEEISEQIEIKKPKKKK 625
>UniRef100_UPI0000431AEC UPI0000431AEC UniRef100 entry
Length = 1509
Score = 68.9 bits (167), Expect = 4e-10
Identities = 112/459 (24%), Positives = 190/459 (40%), Gaps = 67/459 (14%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P P + +E+ ++ KKKK KE+ + ++V
Sbjct: 1048 QVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEV 1107
Query: 60 LLPEPV---VVATAIPITLETPKEQGAEPI------EATVVHPVPDQRPAK------THR 104
L +PV V I +E K + +P+ E T+ P P ++ + T +
Sbjct: 1108 TLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLK 1167
Query: 105 KKKKKE-TVLEPQPE----PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELA 159
KKK KE +VLE E +P PKE E T+ +KK KK+K E EA E+
Sbjct: 1168 KKKPKEKSVLEEVKEEVTLKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEIT 1223
Query: 160 TVCTEP------PAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE 211
EP ++ L + KPKE E V E L IP + PE+ ++ E
Sbjct: 1224 IKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLE--EVKEEVTLKKPIPKEKVPEEVTEQVE 1281
Query: 212 ---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSD 268
P + A E + P++ E+ + T+E L ++ +E+ V +
Sbjct: 1282 IKKPKKKKPVEEEAADEITIKKPEPVEKEEEE-----ITEEVTLKKKKPKEKPVLEEVKE 1336
Query: 269 EKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
E + +P + +P V EQ +P PV +A I + V E++I +
Sbjct: 1337 EVTLKKP---IPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPELVEKEEEEITE 1393
Query: 327 RSRMSKMKRKR---MNSMPDKHNTEPPETKKRVL----DREEPNKCNAKLPETLMLASNC 379
+ K K K + + ++ + P+ K++VL ++ E K K P A
Sbjct: 1394 DITLKKKKPKEKPVLEEVTEEITLKKPKEKEKVLEEVTEKIEVKKSKKKKPIVEEAADEV 1453
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSE 418
I + + ++ E + P++ R K K + E
Sbjct: 1454 TIKKIVEEETK-------EEEAPEEVVLRPKSKRKSIVE 1485
Score = 59.7 bits (143), Expect = 2e-07
Identities = 117/565 (20%), Positives = 221/565 (38%), Gaps = 50/565 (8%)
Query: 29 QDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEA 88
++ ++ + KK K+K+ EE E E + +PV A IT++ P+ E E
Sbjct: 870 EEVKEEITLKKPIPKEKVPEEISEQIEIKKPKKKKPVEEEAADEITIKKPETVEKEEEEI 929
Query: 89 TVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKG 148
T + ++P + ++ KE V +P P+ + E E T+ +KK KK+K
Sbjct: 930 TEEVTLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPE-------EVTEQVEIKKPKKKKP 982
Query: 149 AESNEA----VAELATVCTEPPAVQGGV-LPEPKPKEPCSTEHPRVCPEPPLGLAIPID- 202
E A + + ++ E + V L + KPKE E V E L IP +
Sbjct: 983 VEEEAADEITIKKPVSIEKEEEEITEEVTLKKKKPKEKPVLE--EVKEEVTLKKPIPKEK 1040
Query: 203 -PEKNRKEAE---PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRR 258
PE+ ++ E P + A E + PI+ E+ + +E L ++ +
Sbjct: 1041 VPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEE-----IIEEVTLKKKKPK 1095
Query: 259 EELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQ--TQPGPVIPVCPNSASLIGQSQTIP 316
E+ V +E + VP + +P + EQ +P PV +A I + P
Sbjct: 1096 EKSVLEEVKEEVTLKKP---VPKEKVPEEITEQVEIKKPKKKKPVEEEAADEITIKKPEP 1152
Query: 317 VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLA 376
+ E++I + + K K K + + + + T K+ + +E K+PE +
Sbjct: 1153 IEKEEEEIIEEVTLKKKKPKEKSVLEE---VKEEVTLKKPVPKE-------KVPEEI--- 1199
Query: 377 SNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQK 436
++ P P + T KK + K++ ++ E + + + K
Sbjct: 1200 -TEQVEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVK 1258
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEG-KMSNAQRNNVLLSEGV-KSNEQPTETP 494
+ P +P + +++ PK + + A + E V K E+ TE
Sbjct: 1259 EEVTLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEV 1318
Query: 495 VQKSVNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSES 551
K P + P ++ + +P+P + + +E + ++ KK K + A E
Sbjct: 1319 TLKKKKPKEKPVLEEVKEEVTLKKPIPKEKVPEEVTE--QVEIKKPKKKKPVEEEAADEI 1376
Query: 552 VHHSSDQNAKTPVQRTESLKLVEAK 576
+ K + TE + L + K
Sbjct: 1377 TIKKPELVEKEEEEITEDITLKKKK 1401
Score = 58.5 bits (140), Expect = 5e-07
Identities = 94/375 (25%), Positives = 158/375 (42%), Gaps = 56/375 (14%)
Query: 19 EKPEPLPSPEQD-QEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPV---VVATAIPIT 74
+KP + E++ E+ KKK+ K+K + EE ++V L +P+ V I
Sbjct: 994 KKPVSIEKEEEEITEEVTLKKKKPKEKPVLEE-----VKEEVTLKKPIPKEKVPEEITEQ 1048
Query: 75 LETPKEQGAEPI------EATVVHPVPDQRPAK------THRKKKKKE-TVLEPQPE--- 118
+E K + +P+ E T+ P P ++ + T +KKK KE +VLE E
Sbjct: 1049 VEIKKPKKKKPVEEEAADEITIKKPEPIEKEEEEIIEEVTLKKKKPKEKSVLEEVKEEVT 1108
Query: 119 -PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEP------PAVQGG 171
+P PKE E T+ +KK KK+K E EA E+ EP ++
Sbjct: 1109 LKKPVPKEKV---PEEITEQVEIKKPKKKKPVE-EEAADEITIKKPEPIEKEEEEIIEEV 1164
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPID--PEKNRKEAE---PNESNAEHPRACPEP 226
L + KPKE E V E L +P + PE+ ++ E P + A E
Sbjct: 1165 TLKKKKPKEKSVLE--EVKEEVTLKKPVPKEKVPEEITEQVEIKKPKKKKPVEEEAADEI 1222
Query: 227 PLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPG 286
+ PI+ E+ + +E L ++ +E+ V +E + +P + +P
Sbjct: 1223 TIKKPEPIEKEEEE-----IIEEVTLKKKKPKEKSVLEEVKEEVTLKKP---IPKEKVPE 1274
Query: 287 FVLEQQ--TQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR---MNSM 341
V EQ +P PV +A I + PV E++I + + K K K + +
Sbjct: 1275 EVTEQVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEVTLKKKKPKEKPVLEEV 1334
Query: 342 PDKHNTEPPETKKRV 356
++ + P K++V
Sbjct: 1335 KEEVTLKKPIPKEKV 1349
Score = 51.6 bits (122), Expect = 6e-05
Identities = 55/232 (23%), Positives = 94/232 (39%), Gaps = 29/232 (12%)
Query: 6 QSELLHSKKRR--REEKPEPL----PSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV 59
Q E+ KK++ EE + + P P + +E+ +++ KKKK KE+ + ++V
Sbjct: 1279 QVEIKKPKKKKPVEEEAADEITIKKPEPVEKEEEEITEEVTLKKKKPKEKPVLEEVKEEV 1338
Query: 60 LLPEPVV---VATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHR------------ 104
L +P+ V + +E K + +P+E + ++P +
Sbjct: 1339 TLKKPIPKEKVPEEVTEQVEIKKPKKKKPVEEEAADEITIKKPELVEKEEEEITEDITLK 1398
Query: 105 -KKKKKETVLEPQPEPEP--EPKETSNTDHSEPTQLCSVKKKKKRKG----AESNEAVAE 157
KK K++ VLE E +PKE E T+ VKK KK+K A + +
Sbjct: 1399 KKKPKEKPVLEEVTEEITLKKPKEKEKV-LEEVTEKIEVKKSKKKKPIVEEAADEVTIKK 1457
Query: 158 LATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKE 209
+ T+ V+ PK K E E + P++ EK KE
Sbjct: 1458 IVEEETKEEEAPEEVVLRPKSKRKSIVEEEEEVTEVTITKPKPVEEEKKSKE 1509
Score = 50.4 bits (119), Expect = 1e-04
Identities = 120/584 (20%), Positives = 212/584 (35%), Gaps = 84/584 (14%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
KK + E+P P + +E+ ++KK + K K++ E + E D+ L + V
Sbjct: 502 KKPEKIEEPLKKPVKPESEEKIKAEKKEKPKMKLEHEELRPLEFDKSELEKYV------- 554
Query: 73 ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLE----------PQPEPEPE 122
P+E E+ P P +P + +KKK + + + P+P+ EPE
Sbjct: 555 -----PEEHE----ESEKPPPEPMPKPYEREKKKKPDQEIEQIPLIKGEPKLPEPDKEPE 605
Query: 123 -----PKETSNTDHSEPTQLCSVKKKK------KRKGAESNEAVAELATVCTEPPAVQGG 171
P++ + E L KK K K A+ E A A +
Sbjct: 606 VKFRIPQKEKPEEEPEKITLKGWKKDKPEDEDIKEFPAKEEEEEAPTAPKKEAEEIILKR 665
Query: 172 VLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPE--PPLG 229
+ KPKE + E +P EK KE + + P E P +
Sbjct: 666 KVKLKKPKEKATKEEEVTFKKP---------EEKKPKEVIEEITLKKEPEKSMEQVPEIF 716
Query: 230 LAIPIDPEKNKGENLTPTDEN-ELDRRNRREELVALVTSDE--KIVNPR--DHLVPLKSI 284
+ P+ EK E T T+ + EE++ + E K V D + KSI
Sbjct: 717 IKKPVVEEKEIEEKETITEVTLKKPEEKISEEIIEEIKKPEAKKPVKKETSDEITVKKSI 776
Query: 285 PGFVLEQQTQPGPVIPVCPNSASLIGQ--SQTIPVVDTEQKINKRSRMSKMKRKRMNSMP 342
E++ ++ I + + I + ++K+++ ++ K K S+
Sbjct: 777 VEEKKEEEIPEQIILKKKKPKEKPIPEEIKEEITLKKLKEKVSEEEQIEIKKPKEKKSV- 835
Query: 343 DKHNTEPPETKKRVLDRE----EPNKCNAKLPETLMLASNCHIDQAIPSDSNP-AVPTNP 397
+K T KK V + E E K P + + + IP + P +
Sbjct: 836 EKEATSEITIKKPVENEEEEILEEVTLKKKKPVLEEVKEEITLKKPIPKEKVPEEISEQI 895
Query: 398 EHKTPKKWKK---------RAKKKNVLLSEGGKSNEH----NGQPTETPVQKSVS---PI 441
E K PKK K KK + E + E +P E PV + V +
Sbjct: 896 EIKKPKKKKPVEEEAADEITIKKPETVEKEEEEITEEVTLKKKKPKEKPVLEEVKEEVTL 955
Query: 442 NAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGV---KSNEQPTETPVQKS 498
P +P + +++ PK + + + + + + V K E+ TE K
Sbjct: 956 KKPIPKEKVPEEVTEQVEIKKPKKKK-PVEEEAADEITIKKPVSIEKEEEEITEEVTLKK 1014
Query: 499 VNPIKAPSIDPT---LPTDQPVPIDLATPKHSEGKMSKAQRRKK 539
P + P ++ + +P+P + + +E K ++KK
Sbjct: 1015 KKPKEKPVLEEVKEEVTLKKPIPKEKVPEEITEQVEIKKPKKKK 1058
Score = 48.1 bits (113), Expect = 7e-04
Identities = 115/533 (21%), Positives = 199/533 (36%), Gaps = 70/533 (13%)
Query: 12 SKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI 71
++K+ +EE P P ++ +E+ ++ ++K ++EE E E QV + I
Sbjct: 140 TEKQMKEEVPIPWARGKKAKEEKSDVPQKVEEKPVEEE--EKLETMQVPWLRDKKMTKKI 197
Query: 72 PITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
P KE+ A+ I++ + PV +R K+K +E L+P E +E
Sbjct: 198 P----EKKEELADDIKSVTLKPV--RREHVPEEKEKLEEVTLKPVKRIPREEEE------ 245
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHP---- 187
E QL K KRK E L + + PE KP E E P
Sbjct: 246 KEEVQL---KPIPKRKSEEKPREEVTLKSFQKPKQEEEKSKKPELKPLEKSKPEAPEKEK 302
Query: 188 -------RVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPID--PEK 238
R PE L + PEK +++ R +P + P++ EK
Sbjct: 303 VQLKPFQREKPEEKLTIISQKLPEKTQEKEIKEVEEISWRRKPKKPSISEESPVEKVAEK 362
Query: 239 NKGENLTPTDENELD-------RRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQ 291
E + +E ++ + +RE+ E+I+ L P+K I E+
Sbjct: 363 IVEEKVIKKEEETIEDFKSIALKPIKREKKPEEREDKEEII-----LKPVKHIK--KEEE 415
Query: 292 QTQPGPVIPV-CPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPP 350
T+ + PV P + + + +++ E+ I + K+K + ++ TE P
Sbjct: 416 STEEIKLKPVEKPEKKIEEKEEKPLKLIEEEKPIESELPWRRDKKKSI----EQKVTEIP 471
Query: 351 ETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAV--PTNPEHKTPKKWKKR 408
+K+V + + K PE + L I + P + P PE + K +K+
Sbjct: 472 IEEKKVEEEQVEVKEKKAEPEMMKLKK---IPEKKPEKIEEPLKKPVKPESEEKIKAEKK 528
Query: 409 AKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEG 468
K K L E + E + E V + P +P P P + +
Sbjct: 529 EKPKMKLEHEELRPLEFDKSELEKYVPEEHEESEKPPPEP-----MPKPYE-----REKK 578
Query: 469 KMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDL 521
K + + + L +G +P + P K P K P ++P I L
Sbjct: 579 KKPDQEIEQIPLIKGEPKLPEPDKEPEVKFRIPQKEK------PEEEPEKITL 625
Score = 43.9 bits (102), Expect = 0.013
Identities = 113/549 (20%), Positives = 203/549 (36%), Gaps = 57/549 (10%)
Query: 32 EQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEPIEATVV 91
E+ K + +K++IK+E +E + +V V + L+ +E+ E + V
Sbjct: 10 EEVILKPTKTEKREIKKETLEKVDLQKVTDKTQFVEKEDTKV-LKIDREEKIEEDKIEKV 68
Query: 92 HPVPDQRPAKTHRKKKKKETVLE--------------PQPEPEPEPKETSNTDH--SEPT 135
+R K +++ +T+L+ P P + K T + E T
Sbjct: 69 ATWRKERKLKEPYHEEEDKTILDVEKDIEFMEKQKEMPVPWVRGKKKLTEKVPYHKEEDT 128
Query: 136 QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPL 195
L ++K +K + E V P +G E K P E V E L
Sbjct: 129 TLLDIEKTEKTTEKQMKEEVPI--------PWARGKKAKEEKSDVPQKVEEKPVEEEEKL 180
Query: 196 G-LAIPI--DPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENEL 252
+ +P D + +K E E A+ ++ P+ + EK K E +T +
Sbjct: 181 ETMQVPWLRDKKMTKKIPEKKEELADDIKSVTLKPVRRE-HVPEEKEKLEEVTLKPVKRI 239
Query: 253 DRRNRREELVALVT-----SDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSAS 307
R +E V L S+EK PR+ V LKS E++ P + S
Sbjct: 240 PREEEEKEEVQLKPIPKRKSEEK---PREE-VTLKSFQKPKQEEEKSKKPELKPLEKSKP 295
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPET------KKRVLDREE 361
+ + + + +++ +++ + +K +K E E KK + E
Sbjct: 296 EAPEKEKVQLKPFQRE-KPEEKLTIISQKLPEKTQEKEIKEVEEISWRRKPKKPSISEES 354
Query: 362 P-NKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGG 420
P K K+ E ++ ++ I + A+ K P++ R K+ ++L
Sbjct: 355 PVEKVAEKIVEEKVIKKE---EETIEDFKSIALKPIKREKKPEE---REDKEEIILKPVK 408
Query: 421 ---KSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNN 477
K E + PV+K I P ++ PI+ P + K S Q+
Sbjct: 409 HIKKEEESTEEIKLKPVEKPEKKIEEKEEKPLKLIEEEKPIESELPWRRDKKKSIEQKVT 468
Query: 478 VLLSEGVKSNEQPTETPVQKS-VNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQR 536
+ E K E+ E +K+ +K I P P+ SE K+ KA++
Sbjct: 469 EIPIEEKKVEEEQVEVKEKKAEPEMMKLKKIPEKKPEKIEEPLKKPVKPESEEKI-KAEK 527
Query: 537 RKKNKRALK 545
++K K L+
Sbjct: 528 KEKPKMKLE 536
Score = 40.0 bits (92), Expect = 0.19
Identities = 81/431 (18%), Positives = 163/431 (37%), Gaps = 47/431 (10%)
Query: 10 LHSKKRRREEKPEPLPSP---EQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVV 66
+ K EEK E + P ++ + +KK IK ++ + V + +
Sbjct: 169 VEEKPVEEEEKLETMQVPWLRDKKMTKKIPEKKEELADDIKSVTLKPVRREHVPEEKEKL 228
Query: 67 VATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRK--------KKKKETVLEPQPE 118
+ P+E+ E E + P+P ++ + R+ K K+E +PE
Sbjct: 229 EEVTLKPVKRIPREE--EEKEEVQLKPIPKRKSEEKPREEVTLKSFQKPKQEEEKSKKPE 286
Query: 119 PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ--GGVLPEP 176
+P K E QL K ++ K E +++ T+ ++ +
Sbjct: 287 LKPLEKSKPEAPEKEKVQL---KPFQREKPEEKLTIISQKLPEKTQEKEIKEVEEISWRR 343
Query: 177 KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP 236
KPK+P +E P +A I EK K+ E E+ + +P P +
Sbjct: 344 KPKKPSISEE-----SPVEKVAEKIVEEKVIKKEE--ETIEDFKSIALKPIKREKKPEER 396
Query: 237 EKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPG 296
E + L P + + + E + V EK + ++ PLK ++E++
Sbjct: 397 EDKEEIILKPVKHIKKEEESTEEIKLKPVEKPEKKIEEKEE-KPLK-----LIEEEKPIE 450
Query: 297 PVIPVCPNSASLIGQSQT-IPVVD---TEQKINKRSRMSKMKRKRMNSMPDKHNTEPPET 352
+P + I Q T IP+ + E+++ + + ++ + ++ +P+K + E
Sbjct: 451 SELPWRRDKKKSIEQKVTEIPIEEKKVEEEQVEVKEKKAEPEMMKLKKIPEKKPEKIEEP 510
Query: 353 KKRVLDREEPNKCNAKLPETLMLA-----------SNCHIDQAIPSDSNPAVPTNPEHKT 401
K+ + E K A+ E + +++ +P + + PE
Sbjct: 511 LKKPVKPESEEKIKAEKKEKPKMKLEHEELRPLEFDKSELEKYVPEEHEESEKPPPE-PM 569
Query: 402 PKKWKKRAKKK 412
PK +++ KKK
Sbjct: 570 PKPYEREKKKK 580
>UniRef100_UPI000021B299 UPI000021B299 UniRef100 entry
Length = 2011
Score = 68.2 bits (165), Expect = 7e-10
Identities = 78/286 (27%), Positives = 111/286 (38%), Gaps = 45/286 (15%)
Query: 18 EEKPEPLPSPEQDQEQSC---------SKKKRRKKKKIKEEGIESHEHDQVLL-PEPVVV 67
E +PEP P PE+ +E+S +KK ++KKK ++E +E PEP V
Sbjct: 498 EPEPEPEPEPEKKEEESSGWGIWGAATTKKDKKKKKVVEEPKVEEPPPPPPAPEPEPAPV 557
Query: 68 ATAI---PITLETPKEQGAEPIEAT-------VVHPVPDQRPAK-----------THRKK 106
+A T T K++G +E V P P+ P K + + K
Sbjct: 558 ESAWGWGTTTTTTKKKKGKNAVEEAPPPEPEPVKEPDPEPEPEKKVEEDIWGLSTSKKDK 617
Query: 107 KKKETVLE--PQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTE 164
KKK+ +E P+P PE +P E D + + KK K K E ++ ++
Sbjct: 618 KKKKGAVEEVPEPPPEEKPAEDEKKDDFDFGFTATSSKKDKDKDKEKDKKKKTKSSSIWG 677
Query: 165 PPAVQGGVLPEP-KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEA-EPNESNAEHPRA 222
P PEP KP EP E +G D +K K A EP P
Sbjct: 678 EPVKDPEPEPEPEKPAEPEKKEEDDFWAS--IGGTSKKDKKKKGKTAEEPPPPPPAEPEP 735
Query: 223 CPEPP--------LGLAIPIDPEKNKGENLTPTDENELDRRNRREE 260
PEP G A +K KG+ P E E + + EE
Sbjct: 736 EPEPEKTEDFDFGWGAAATKKDKKKKGKTAEPDPEPEPEPEKKVEE 781
Score = 60.1 bits (144), Expect = 2e-07
Identities = 62/242 (25%), Positives = 93/242 (37%), Gaps = 28/242 (11%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVV--VATAIPITLE 76
E P+P+ P +D + S KK +KKKK E ++ + P P + A +
Sbjct: 406 EPPKPVDPPPEDIWGAVSSKKDKKKKKGAAEEVKEEPPKEPDPPPPPAEDIWGAAASKKD 465
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQ 136
T K++G I P + P K+ + E EP+PEPEPE KE ++
Sbjct: 466 TKKKKGKASIWG---EPAKEPEPEPEPVKEPEPEPEPEPEPEPEPEKKEEESSGWGIWGA 522
Query: 137 LCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLG 196
+ K KKK+K E + EPP PEP P E G
Sbjct: 523 ATTKKDKKKKKVVEEPKV--------EEPPPPPPAPEPEPAPVESA------------WG 562
Query: 197 LAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRN 256
K +K E E P PEP +PEK E++ ++ D++
Sbjct: 563 WGTTTTTTKKKKGKNAVE---EAPPPEPEPVKEPDPEPEPEKKVEEDIWGLSTSKKDKKK 619
Query: 257 RR 258
++
Sbjct: 620 KK 621
Score = 53.1 bits (126), Expect = 2e-05
Identities = 69/282 (24%), Positives = 104/282 (36%), Gaps = 70/282 (24%)
Query: 14 KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPI 73
K ++P+P P P +D + + KK KKKK K + PEPV
Sbjct: 439 KEEPPKEPDPPPPPAEDIWGAAASKKDTKKKKGKASIWGEPAKEPEPEPEPV-------- 490
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRP----------AKTHRKKKKKETVLE--------- 114
KE EP P P+++ A T +K KKK+ V+E
Sbjct: 491 -----KEPEPEPEPEPEPEPEPEKKEEESSGWGIWGAATTKKDKKKKKVVEEPKVEEPPP 545
Query: 115 --PQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAES--------------------- 151
P PEPEP P E++ T + KKKK + E
Sbjct: 546 PPPAPEPEPAPVESA---WGWGTTTTTTKKKKGKNAVEEAPPPEPEPVKEPDPEPEPEKK 602
Query: 152 -NEAVAELATVCTEPPAVQGGV--LPEPKPKEPCSTEHPRVCPEPPLGLAIPI------- 201
E + L+T + +G V +PEP P+E + + + + G
Sbjct: 603 VEEDIWGLSTSKKDKKKKKGAVEEVPEPPPEEKPAEDEKK--DDFDFGFTATSSKKDKDK 660
Query: 202 DPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGEN 243
D EK++K+ + S P PEP P +PEK + ++
Sbjct: 661 DKEKDKKKKTKSSSIWGEPVKDPEPEPEPEKPAEPEKKEEDD 702
Score = 50.8 bits (120), Expect = 1e-04
Identities = 65/263 (24%), Positives = 98/263 (36%), Gaps = 74/263 (28%)
Query: 13 KKRRREEKPEPLPSP----------------------EQDQEQSCSKKKRRKKKKIKEEG 50
KK EE PEP P ++D+++ KKK+ K I E
Sbjct: 620 KKGAVEEVPEPPPEEKPAEDEKKDDFDFGFTATSSKKDKDKDKEKDKKKKTKSSSIWGEP 679
Query: 51 IESHEHDQVLLPEPVVVA-----------TAIPITLETPKEQ----GAEPIEATVVHPVP 95
++ E + PEP A +I T + K++ EP P P
Sbjct: 680 VKDPEPE----PEPEKPAEPEKKEEDDFWASIGGTSKKDKKKKGKTAEEPPPPPPAEPEP 735
Query: 96 DQRPAKTH------------RKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKK 143
+ P KT + KKKK EP PEPEPEP++ D + + KK
Sbjct: 736 EPEPEKTEDFDFGWGAAATKKDKKKKGKTAEPDPEPEPEPEKKVEEDDFW-ASIGTGKKD 794
Query: 144 KKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDP 203
K +K + ++A+ +L T PKE E G + D
Sbjct: 795 KDKKKKKGDDALIDLET-----------------PKEEKKEEKDDFWSS--FGTSSKKDK 835
Query: 204 EKNRKEAEPNESNAEHPRACPEP 226
+K++K+ + ES+ + P A EP
Sbjct: 836 DKDKKKKDKEESSVK-PDAIEEP 857
Score = 49.3 bits (116), Expect = 3e-04
Identities = 110/560 (19%), Positives = 200/560 (35%), Gaps = 87/560 (15%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQV--- 59
S S+ + S K + ++K S ++D+++ K + K K+ +E + + DQ
Sbjct: 1145 SSSKDKEKSSSKSKSKDKDAKSSSKDKDKDKDKKSKDKDKDKEKDKEADKEADKDQDDFD 1204
Query: 60 ---------LLPEPV--VVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKK 108
L PE V ++ P +E PKE A + + A + KK +
Sbjct: 1205 KELEKDLLNLTPENVEELLNEEPPAEVEKPKEAPASDAFSFWGASKKGAKSATSEIKKAE 1264
Query: 109 KETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAV 168
T+ PE D+S K K+ G++ + + T PP
Sbjct: 1265 SSTI--------PEDATDGLGDNSADVSSGKATKSSKKVGSKVADRLKAFQASTTPPPEE 1316
Query: 169 QGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHP---RACPE 225
+ V+P+P P P PP A P E +K+ + ++ A P PE
Sbjct: 1317 EEEVIPDPVPP-----------PPPPPPPAEPPAEESGKKKKKSKKAAAVAPEVVEVVPE 1365
Query: 226 PPLGLAIPIDPEKNKGENLTPTDENELDR------RNRREELVALVTSDEKIVNPRDHLV 279
+ PE E TP + +E+V +V + + +
Sbjct: 1366 VVPEVEAEAPPEVEIVEEPTPPRRKVRSHLPGSFPMDDEDEIVDIVDMSPEKKSSKKSKS 1425
Query: 280 PLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRK--- 336
KS V P P P P++ + + P E+K +K+ R +K+ R+
Sbjct: 1426 RSKSGSVSVPPAAPPPPPPPPAVPDAPPAVPDA---PPSTEEEKPSKKER-AKISREGSA 1481
Query: 337 ---RMNSMPDKHNTEPPETKKR------VLDREEPNKCN---AKLPETLMLASNCHIDQA 384
N+ P K P ++++ E P + AK +LAS + ++
Sbjct: 1482 SWGMWNAAPRKEEKRPSRSERKESGSSSKTREERPERIKEAPAKARVASVLASTPPLSRS 1541
Query: 385 I-------------PSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTE 431
++ N + + P + P+ K A+ L S G + ++ P
Sbjct: 1542 ASTREKKSSSRSRRSAEVNHGLASPPPEEAPEMTDKAARIFG-LKSSGSRRSKTRSAP-- 1598
Query: 432 TPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNA------QRNNVLLSEGV- 484
P + + + A P P+ + +++ + K A +R V E +
Sbjct: 1599 -PEDEDIVMVGALDASPEKPSRRRSKVNIDLVQRQTRKWGRATDLTQREREQVPRDEDIV 1657
Query: 485 -KSNEQPTETPVQKSVNPIK 503
N PT TP+++S + K
Sbjct: 1658 MVDNPDPT-TPLKRSNSSAK 1676
Score = 43.1 bits (100), Expect = 0.022
Identities = 82/417 (19%), Positives = 139/417 (32%), Gaps = 76/417 (18%)
Query: 21 PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKE 80
P P P P + + KKK++ KK + PE V V + P+
Sbjct: 1328 PPPPPPPAEPPAEESGKKKKKSKKAA------------AVAPEVVEVVPEV-----VPEV 1370
Query: 81 QGAEPIEATVVH-PVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCS 139
+ P E +V P P +R ++H P P + E + P + S
Sbjct: 1371 EAEAPPEVEIVEEPTPPRRKVRSHL----------PGSFPMDDEDEIVDIVDMSPEKKSS 1420
Query: 140 VKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAI 199
K K + K + PPA P P P P + P P+ P
Sbjct: 1421 KKSKSRSKSGS-----------VSVPPAA-----PPPPPPPPAVPDAPPAVPDAP----- 1459
Query: 200 PIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRRE 259
P E+ + E + + E + + A P EK + + R R
Sbjct: 1460 PSTEEEKPSKKERAKISREGSASWG---MWNAAPRKEEKRPSRSERKESGSSSKTREERP 1516
Query: 260 ELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVD 319
E + + ++ + L S P T+ SA + + P +
Sbjct: 1517 ERIKEAPAKARVASV------LASTPPLSRSASTREKKSSSRSRRSAEVNHGLASPPPEE 1570
Query: 320 TEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVL------DREEPNKCNAKLPETL 373
+ +K +R+ +K S K + PPE + V+ E+P++ +K+ L
Sbjct: 1571 APEMTDKAARIFGLKSS--GSRRSKTRSAPPEDEDIVMVGALDASPEKPSRRRSKVNIDL 1628
Query: 374 MLASNCHIDQA----------IPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGG 420
+ +A +P D + + NP+ TP K + KK + GG
Sbjct: 1629 VQRQTRKWGRATDLTQREREQVPRDEDIVMVDNPDPTTPLKRSNSSAKKGLAGLFGG 1685
Score = 41.6 bits (96), Expect = 0.065
Identities = 59/240 (24%), Positives = 76/240 (31%), Gaps = 65/240 (27%)
Query: 78 PKEQGA------------EPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKE 125
PK++GA E IE PV KKK EP+ EPEPEP +
Sbjct: 350 PKKKGATGFSFGDIGEVEEVIEPKKEEPVASDDWGGWGTAGKKKGKKAEPETEPEPEPPK 409
Query: 126 TSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPP------------------- 166
+ + S KK KK+K + E E PP
Sbjct: 410 PVDPPPEDIWGAVSSKKDKKKKKGAAEEVKEEPPKEPDPPPPPAEDIWGAAASKKDTKKK 469
Query: 167 ----AVQGGVLPEPKPK-EPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPN-------- 213
++ G EP+P+ EP P PEP +PE +KE E +
Sbjct: 470 KGKASIWGEPAKEPEPEPEPVKEPEPEPEPEP------EPEPEPEKKEEESSGWGIWGAA 523
Query: 214 -------------ESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREE 260
E E P P PP P E G T T + +N EE
Sbjct: 524 TTKKDKKKKKVVEEPKVEEPP--PPPPAPEPEPAPVESAWGWGTTTTTTKKKKGKNAVEE 581
Score = 37.4 bits (85), Expect = 1.2
Identities = 36/158 (22%), Positives = 62/158 (38%), Gaps = 18/158 (11%)
Query: 13 KKRRREE---KPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVAT 69
KK+ +EE KP+ + P +D S KK++ K K +E + +A+
Sbjct: 840 KKKDKEESSVKPDAIEEPSEDIWGVSSSKKKKDKSSSKNVPVE--------VVGDTDIAS 891
Query: 70 AIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNT 129
P ++E K+ G + K KKK+KE EP+ + + K
Sbjct: 892 VQPDSIEEAKDDGGW-------FGTSSKSKDKDKEKKKEKEKEKEPKLSKKEQEKLDKEK 944
Query: 130 DHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPA 167
+ + K++ K++ E+ A E A E A
Sbjct: 945 EKERKKAEKAEKERAKQEAEEAARAEEEAARAAEEAAA 982
>UniRef100_Q9JM99 Mus musculus [Mus musculus]
Length = 1054
Score = 68.2 bits (165), Expect = 7e-10
Identities = 121/537 (22%), Positives = 175/537 (32%), Gaps = 87/537 (16%)
Query: 4 HSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPE 63
+S++ S +E E + +++ S SKKK +KE D+ + P
Sbjct: 264 NSETSKEASLASNKETTVETKETTATNKQSSASKKKTTS---VKETRSAEKTSDKDVEPT 320
Query: 64 PVVVATAIPITLETP----KEQG-----AEPIEATVVHPVPD-QRPAKTHRKKKKKETVL 113
+ P T + P KE EP T P P ++P T RK+ + T
Sbjct: 321 STTPKNSAPTTTKKPVTTTKESKFLPLPQEPEPTTAKEPPPTTKKPEPTTRKEPEPTTPK 380
Query: 114 EPQP----EPEPE-PKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAV 168
EP+P EPEP PKE T EP + KK + E T P
Sbjct: 381 EPEPTTPKEPEPTTPKEPEPTTPKEPPP--TTKKPEPTTPKEPGP---------TTPKEP 429
Query: 169 QGGVLPEPKP---KEPCSTEHPRVCPEPPLGLAIPIDPEKNR-KEAEPNESNAEHPRACP 224
+ EP+P KEP ST PEP P +PE KE EP P
Sbjct: 430 EPTTTKEPEPTTTKEPESTTRKE--PEP----TTPKEPEPTTPKEPEPTTLKEPEPTTPK 483
Query: 225 EPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSI 284
EP P +PE + PT E + +E P P +
Sbjct: 484 EPEP--TTPKEPEPTTPKEPEPTTPKEPEPTTPKEP------------EPTTPKEPEPTT 529
Query: 285 PGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDK 344
P +P P P P + T P K + K + +
Sbjct: 530 P-------KEPEPTTPKEPEPTTPKKPEPTTP---------KEPVPTTPKEPEPTTPKEP 573
Query: 345 HNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKK 404
T P E + R+EP K PE P + P P PE T
Sbjct: 574 EPTTPKEPEPTT--RKEPEPTTPKEPEP-----------TTPKEPEPTTPKKPEPTTTSP 620
Query: 405 WKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPK 464
K + + E +P ET S + ++ P PT P P P
Sbjct: 621 KTTTLKATTLAPKVTAPAEEIQNKPEETTPASEDSDDSKTTLKPQKPTKAPKP--TKKPT 678
Query: 465 HSEGKMSNAQRNNVLLSEGVKSNEQP---TETPVQKSVNPIKAPSIDPTLPTDQPVP 518
+ K ++ ++ + K+ P T + + P++ T+P P P
Sbjct: 679 KAPKKPTSTKKPKTPKTRKPKTTPAPLKTTSATPELNTTPLEVMLPTTTIPKQTPNP 735
Score = 52.4 bits (124), Expect = 4e-05
Identities = 100/488 (20%), Positives = 151/488 (30%), Gaps = 97/488 (19%)
Query: 72 PITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
P + P GA + P +T + + +E E + E +E+S++
Sbjct: 113 PSSKTAPTPAGASDTIKSTTKRSPKSPTTRTIKVVESEELTEE---HSDSENQESSSSSS 169
Query: 132 SEPTQLCSVKKKK--------KRKGAESNEAVAELATVCTEPPAVQ--------GGVLPE 175
S + + +K K K + N+ EPPAV G
Sbjct: 170 SSSSTIRKIKSSKNSANRELQKNPNVKDNKKNTPKKKPNPEPPAVDEAGSGLDNGEFKLT 229
Query: 176 PKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPID 235
P P +P +T H +V P A P+ P+ P P +
Sbjct: 230 PPPPDPPTTPHSKVATSPKTTAAKPVTPK---------------PSLAP----------N 264
Query: 236 PEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQP 295
E +K +L E ++ + S +K + ++ K+ V T P
Sbjct: 265 SETSKEASLASNKETTVETKETTATNKQSSASKKKTTSVKETRSAEKTSDKDVEPTSTTP 324
Query: 296 GPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKK- 354
P PV T++ SK P PP TKK
Sbjct: 325 KNSAPTTTKK----------PVTTTKE--------SKFLPLPQEPEPTTAKEPPPTTKKP 366
Query: 355 RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKK-KN 413
R+EP K PE P + P P PE TPK+ KK +
Sbjct: 367 EPTTRKEPEPTTPKEPE-----------PTTPKEPEPTTPKEPEPTTPKEPPPTTKKPEP 415
Query: 414 VLLSEGGKSNEHNGQPT-------------ETPVQKSVSPINAPSIDPTLPTDQPVPIDL 460
E G + +PT E+ +K P +PT P +P P L
Sbjct: 416 TTPKEPGPTTPKEPEPTTTKEPEPTTTKEPESTTRKEPEPTTPKEPEPTTP-KEPEPTTL 474
Query: 461 ATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPID 520
P+ + K + E + + E K P +PT P +P P
Sbjct: 475 KEPEPTTPK----EPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTP-KEPEP-- 527
Query: 521 LATPKHSE 528
TPK E
Sbjct: 528 -TTPKEPE 534
>UniRef100_Q7PF94 ENSANGP00000024414 [Anopheles gambiae str. PEST]
Length = 1400
Score = 67.8 bits (164), Expect = 9e-10
Identities = 137/599 (22%), Positives = 224/599 (36%), Gaps = 102/599 (17%)
Query: 14 KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVV--VATAI 71
K+ E+KP P P+ + EQ K R+KK++ +E IE V +PVV VATA
Sbjct: 167 KKSVEKKPLPTPAEPEKVEQVTLKPTPRQKKELPKEAIEEVSLKPV-PKKPVVEEVATAE 225
Query: 72 PITLE--------------TPKEQGAEPIE------ATVVHPVPDQRPAKTHRKK----- 106
P +E +++ E ++ VP+++ T +++
Sbjct: 226 PEEVEEKTVKIVKKKKPKAVTQQESLEKLDWRRQQKPKPQEEVPEEKQWPTGKRRPLPEE 285
Query: 107 KKKETVLEPQPEP--EPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVC-- 162
K+E VL+P P+P E EPKET +P + + K + + AV E T
Sbjct: 286 PKEEIVLKPIPKPTKENEPKETKE-QTIKPKPISELDDKPEPELELEKPAVPEEDTSLPP 344
Query: 163 ----------TEPPAVQGGVLPEPKPKEPCSTEHP----RVCPEPPLGLAIPIDPEKNRK 208
E P+ + P+P+ + P + P R PE P + K K
Sbjct: 345 WLKPIEPEQEPEKPSWRRQQKPKPQEEVPEEKQWPTGKRRPLPEEPKEEVVLKPIPKPTK 404
Query: 209 EAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELD--RRNRREELVALVT 266
E EP ES + P P+P L +PE + P ++ L RR ++ +
Sbjct: 405 EVEPTES--KEPTIKPKPMPELDDKPEPELELEQPAVPEEDTSLPPWRRGKKPVPKREIP 462
Query: 267 SDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
+ E V L P + ++ + + PV S + T+ + + + K
Sbjct: 463 APEPAVMETVTLKPTPKRAKELPQESIEEVSLKPVPQKSEVEEVPADTVSIAEVKDISPK 522
Query: 327 RSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIP 386
+ + K +++ + + E PE ++ L++ E HI + +
Sbjct: 523 KVKKPK-RKEELEPLEKPVYPEIPEQEEVQLEKTE------------------HIPEEVQ 563
Query: 387 SDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKS--NEHNGQPTETPVQKSV-SPINA 443
+ VP P W++ K K V E K P E P ++ V PI
Sbjct: 564 KEPE-TVPEQP------PWRRTPKPKPVETEEEEKKWPTGKRRPPVEEPKEEVVLKPIPK 616
Query: 444 PSIDPTLPTDQPVPIDLATPKHSE---------------GKMSNAQRNNVLLSEGVKSNE 488
P+ D +Q + I PKH E GK E K
Sbjct: 617 PTKDVEPQPEQQITI---KPKHPEPTPKEEIPEVTPWRRGKKEKPPVEEEEPKEWPKGKR 673
Query: 489 QP-TETPVQKSV-NPIKAPS-IDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRAL 544
+P ETP ++ V PI PS +P P ++P I L P E + K ++ + L
Sbjct: 674 RPLPETPKEEVVLKPIPKPSKEEPPKPAEEPT-IVLPKPTVQEPEEPKQAPWRRGMKEL 731
Score = 53.5 bits (127), Expect = 2e-05
Identities = 127/584 (21%), Positives = 221/584 (37%), Gaps = 118/584 (20%)
Query: 79 KEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQL- 137
K+ E +E ++ P P Q+ K+ KE + E +P P+ +EP ++
Sbjct: 1 KQPEPEKVEQVMLKPTPRQK------KELPKEAIEEVSLKPVPKKPVVEEVATAEPEEVE 54
Query: 138 ---CSVKKKKKRKGA-----------ESNEAVAELATVCT-------EPPAVQGGVLPEP 176
+ KKKK K + E V E T E P + + P P
Sbjct: 55 EKTVKIVKKKKPKSVTQQDWRRQQKLKPQEEVPEEKQWPTGKRRPLPEEPKEEVVLKPIP 114
Query: 177 KP---KEPCSTEHPRVCPEPPLGLAIPIDPE-KNRKEAEPNESNAEHP-----RACPEPP 227
KP EP T+ + P+P L +PE + K A P E + P ++ + P
Sbjct: 115 KPTKENEPKETKEQTIKPKPMPELDDKPEPELELEKPAVPEEDTSLPPWRRGKKSVEKKP 174
Query: 228 LGLAIPIDPEKNKGENLTPTDENELDRRNRREELVAL------------VTSDEKIVNPR 275
L P +PEK + L PT + + E V+L T++ + V +
Sbjct: 175 --LPTPAEPEKVEQVTLKPTPRQKKELPKEAIEEVSLKPVPKKPVVEEVATAEPEEVEEK 232
Query: 276 DHLVPLKSIPGFVLEQ----------QTQPGPVIPVCPNSASLIGQSQTIPVVDTEQ--- 322
+ K P V +Q Q +P P V G+ + +P E+
Sbjct: 233 TVKIVKKKKPKAVTQQESLEKLDWRRQQKPKPQEEVPEEKQWPTGKRRPLPEEPKEEIVL 292
Query: 323 -KINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEP--NKCNAKLPETLMLASNC 379
I K ++ ++ K + ++ K +E + + L+ E+P + + LP L
Sbjct: 293 KPIPKPTKENEPKETKEQTIKPKPISELDDKPEPELELEKPAVPEEDTSLPPWL------ 346
Query: 380 HIDQAIPSDSNPAVPT-------NPEHKTP--KKW---KKR----AKKKNVLLSEGGKSN 423
+ I + P P+ P+ + P K+W K+R K+ V+L K
Sbjct: 347 ---KPIEPEQEPEKPSWRRQQKPKPQEEVPEEKQWPTGKRRPLPEEPKEEVVLKPIPKPT 403
Query: 424 EHNGQPTETPVQKSVSPINAPSID----PTLPTDQP-VP-IDLATPKHSEGKMSNAQRNN 477
+ +PTE+ + ++ P P +D P L +QP VP D + P GK +R
Sbjct: 404 K-EVEPTESK-EPTIKPKPMPELDDKPEPELELEQPAVPEEDTSLPPWRRGKKPVPKREI 461
Query: 478 VLLSEGV-----------KSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKH 526
V ++ E P E+ + S+ P+ S +P D + +A K
Sbjct: 462 PAPEPAVMETVTLKPTPKRAKELPQESIEEVSLKPVPQKSEVEEVPAD---TVSIAEVKD 518
Query: 527 SEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESL 570
K K +RK+ L+ + V+ + + +++TE +
Sbjct: 519 ISPKKVKKPKRKEELEPLE----KPVYPEIPEQEEVQLEKTEHI 558
>UniRef100_Q14676 KIAA0170 protein [Homo sapiens]
Length = 2090
Score = 67.8 bits (164), Expect = 9e-10
Identities = 123/553 (22%), Positives = 195/553 (35%), Gaps = 121/553 (21%)
Query: 60 LLP--EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP 117
LLP +P V T + E P+ + +E HP P R K+ R T P+P
Sbjct: 1071 LLPSIKPTVRKTRQDGSQEAPEAPLSSELEP--FHPKPKIRTRKSSRMTPFPATSAAPEP 1128
Query: 118 EPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPK 177
P T+ +PT + + + R ++ E V V T P +P
Sbjct: 1129 HPS---TSTAQPVTPKPTSQ-ATRSRTNRSSVKTPEPV-----VPTAPELQPSTSTDQPV 1179
Query: 178 PKEPCS-------TEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRA-------- 222
EP S + PE + A+ + P + +E ++ R
Sbjct: 1180 TSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVK 1239
Query: 223 CPEPPLGLAIPIDPEKNKGENLT--PTDENELDRRNRREELVALVTSDEKIVNPRDHLVP 280
PEP + A + P + + +T PT + R+NR + V + E +V L P
Sbjct: 1240 TPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR-----SSVKTPEPVVPTAPELRP 1294
Query: 281 LKSIPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINK 326
S V + T P V+P P Q + T +
Sbjct: 1295 STSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRS 1354
Query: 327 RSRMSKMKRKRMN-----SMPDKHNTEPPETKKRV--LDREEPNKCNAKLPETLMLASNC 379
R+ MS +K +P +TE P T + R N+ + K PETL
Sbjct: 1355 RTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETL------ 1408
Query: 380 HIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVS 439
VPT P+ + + + + G++N + + ET V
Sbjct: 1409 -------------VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVP---- 1451
Query: 440 PINAPSIDPTLPTDQPVPIDLATPK-HSEGKMSNAQRNNVLLSEGV----------KSNE 488
AP + P+ TDQPV TP+ S+ R++V E V S +
Sbjct: 1452 --TAPELQPSTSTDQPV-----TPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTD 1504
Query: 489 QP-TETPVQKSVNPIK--------------APSIDPTLPTDQPVPIDLATPKHSEGKMSK 533
QP T P ++ K AP + P TD+PV TP+ + S+
Sbjct: 1505 QPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPV-----TPEPT----SR 1555
Query: 534 AQRRKKNKRALKS 546
A R + N+ ++K+
Sbjct: 1556 ATRGRTNRSSVKT 1568
Score = 61.6 bits (148), Expect = 6e-08
Identities = 135/650 (20%), Positives = 232/650 (34%), Gaps = 112/650 (17%)
Query: 3 SHSQSELLHSKKRRREEK-PEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
S S++ +K R K PE + + + S S + + + V
Sbjct: 1181 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT 1240
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQP--EP 119
PEPVV TA + T +Q PV + + R +K + +V P+P
Sbjct: 1241 PEPVV-PTAPELQPSTSTDQ-----------PVTSEPTYQATRGRKNRSSVKTPEPVVPT 1288
Query: 120 EPEPKETSNTDHS---EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
PE + +++TD +PT + + + ++ E V A + V P+P
Sbjct: 1289 APELRPSTSTDRPVTPKPTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1347
Query: 177 KPKEP------CSTEHPR----VCPEPPLGLAI--PIDPEKNRKEAEPNESNAEHPRACP 224
+ S ++P + PE P + P+ PE + ++ + P
Sbjct: 1348 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKT--P 1405
Query: 225 EPPLGLAIPIDPEKNKGENLTPTDENELDR-RNRREELVALVTSDEKIVNPRDHLVPLKS 283
E + A ++P + + +TP ++ R R R V + E +V L P S
Sbjct: 1406 ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSS----VKTPETVVPTAPELQPSTS 1461
Query: 284 IPGFVLEQQTQ--------------PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSR 329
V + T P V+P P + Q + T + R
Sbjct: 1462 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKN 1521
Query: 330 MSKMKRKRMNSMPDKHNTEPPETKKRVLDRE--------EPNKCNAKLPETLM------- 374
S +K +P +PP + R + E N+ + K PE+++
Sbjct: 1522 RSSVKTPE-TVVPAAPELQPPTSTDRPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQ 1580
Query: 375 ---------------LASNCHIDQAIPSDSNPAVPTNPE-HKTPKKWKKRAKKKNVLLSE 418
A+ C +++ P VPT PE H T + K L+
Sbjct: 1581 PSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPK----LTS 1636
Query: 419 GGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH-SEGKMSNAQRNN 477
+ N +TP K V P A ++P PTDQ V TP+ ++G S R++
Sbjct: 1637 RATRRKTNRSSVKTP--KPVEPA-ASDLEPFTPTDQSV-----TPEAIAQGGQSKTLRSS 1688
Query: 478 VLLSEGVKSN---EQPTETPVQKSVNPIKAPSIDPTL-----PTDQPVPIDLATPKHSEG 529
+ + V + + P T S PI PS P PID K
Sbjct: 1689 TVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPID---HKPCSA 1745
Query: 530 KMSKAQRRKKNKR--ALKSAWSESV--HHSSDQNAKTPVQRTESLKLVEA 575
+ + +N+R A+++A S + +S Q +TP+ ++ K+ A
Sbjct: 1746 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPA 1795
Score = 45.1 bits (105), Expect = 0.006
Identities = 121/619 (19%), Positives = 216/619 (34%), Gaps = 127/619 (20%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIE-SHEHDQVLLPEP 64
++E L +++ E L +QD+EQ + ++++ + G S E D+ L
Sbjct: 835 ETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVE 894
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPK 124
+ + I + ++ E V PV ++ ++K + +LE
Sbjct: 895 IETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILE---------- 944
Query: 125 ETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP-------- 176
+T EP + +KG S+ T P V G LP P
Sbjct: 945 --RDTQRGEPEG-----GSQDQKGQASSP---------TPEPGVGAGDLPGPTSAPVPSG 988
Query: 177 -------KPKEPCSTEHPRV-CPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPL 228
P P + + C PP A I + + +A P A PE P
Sbjct: 989 SQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPAVPEAPA 1048
Query: 229 GLAIPIDPEKNKG-----------ENLTPTDENELDRRNRREELVALVTSDEKIVNPRDH 277
P++ + K ++ PT + + +E A ++S+ + +P+
Sbjct: 1049 PPQKPLNSQSQKHLAPPPLLSPLLPSIKPT-VRKTRQDGSQEAPEAPLSSELEPFHPKPK 1107
Query: 278 LVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKR 337
+ KS + P P P +Q + T Q R+ S +K
Sbjct: 1108 IRTRKS-------SRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPE 1160
Query: 338 -----MNSMPDKHNTEPPETKKRV--LDREEPNKCNAKLPET-----LMLASNCHIDQAI 385
+ +T+ P T + + R ++ + K PET L L + D+ +
Sbjct: 1161 PVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPV 1220
Query: 386 PSD-----------------SNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQ 428
S+ P VPT PE + + + + G+ N + +
Sbjct: 1221 TSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVK 1280
Query: 429 PTETPVQKSVSPINAPSIDPTLPTDQPV-PIDLATPKHSEGKMSNAQRNNVLLSEGVK-- 485
E V AP + P+ TD+PV P + S MS+ + ++ +
Sbjct: 1281 TPEPVVP------TAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQ 1334
Query: 486 ---SNEQP-TETPVQKSV----------NPIK----APSIDPTLPTDQPVPIDLATPKHS 527
S +QP T P ++ NP AP + P+ T+QPV TP+ +
Sbjct: 1335 ISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPV-----TPEPT 1389
Query: 528 EGKMSKAQRRKKNKRALKS 546
S+A R +KN+ + K+
Sbjct: 1390 ----SRATRGRKNRSSGKT 1404
>UniRef100_Q9BX49 Proteoglycan 4, [Homo sapiens]
Length = 1404
Score = 67.8 bits (164), Expect = 9e-10
Identities = 121/528 (22%), Positives = 172/528 (31%), Gaps = 47/528 (8%)
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP 121
P P P T + P EP P + PA T KK T EP P
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPA------PTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 122 EP-----KETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
EP KE S T EP + K E + A + P+ P P
Sbjct: 505 EPAPTTTKEPSPTTPKEPAP--TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 177 -KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEP----PLGLA 231
PKEP T + P P A P P KE P + P EP P A
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPA-PTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 232 IPIDPEK---NKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRD--HLVPLKSIPG 286
P P+K E L PT E EEL + P + P + P
Sbjct: 618 -PTTPKKLTPTTPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 675
Query: 287 FVLE-QQTQPGPVIPVCPNSASLIGQSQTIPVV--DTEQKINKRSRMSKMKRKRMNSMPD 343
E T P P P + +T P T K + K+ +
Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 344 KHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPK 403
EP T D+ P P T + + P+ PT + P
Sbjct: 736 TTTKEPTST---TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 404 KWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATP 463
KK A K+ + G ++ + +P T K +P PT P +P P TP
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKPAPTTPETP 850
Query: 464 KHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLAT 523
+ ++S E ++ P E+ + S P P P + VP T
Sbjct: 851 PPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVP-TTKT 903
Query: 524 PKHSEGKMSKAQRRKKNKRALKSA--WSESVHHSSDQNAKTPVQRTES 569
P ++ +M+ + K +R L++ + + + + A T + TES
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Score = 51.2 bits (121), Expect = 8e-05
Identities = 105/473 (22%), Positives = 148/473 (31%), Gaps = 40/473 (8%)
Query: 72 PITLETPKEQGAEPIEATVVH-PVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTD 130
P T+++ EP T P + PA T K+ T EP P EP T T
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT--TT 425
Query: 131 HSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVC 190
S PT +K A + E A + P P P KEP T
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 191 PEPPLGLAIPIDPEK----NRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTP 246
P P A P P++ KE P + P EP P + P
Sbjct: 484 PTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEP 537
Query: 247 TDENELDRRNRREELVALVTSDEKIVNPRD--HLVPLKSIPGFVLEQQTQPGPVIPVCPN 304
+E T + P++ P K P +P P P P
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPA 593
Query: 305 SASLIGQSQTIP--VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEP 362
+ + T P T K + K+ + +P T L P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 363 NKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKS 422
+ PE + P + P P P TPK+ K+ + G +
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 423 NEHNGQPTETPVQKSVSPINAPSI--DPTLPT-DQPVPIDLATPKHSEGKMSNAQRNNVL 479
+P T +K AP+ +PT T D+P P TPK G +
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP---TTPK---GTAPTTPKE--- 764
Query: 480 LSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMS 532
E TP + +K P+ PT P +P P +LA P ++G S
Sbjct: 765 -PAPTTPKEPAPTTPKGTAPTTLKEPA--PTTP-KKPAPKELA-PTTTKGPTS 812
Score = 51.2 bits (121), Expect = 8e-05
Identities = 114/593 (19%), Positives = 182/593 (30%), Gaps = 49/593 (8%)
Query: 2 DSHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLL 61
+ HS SE S + + S + ++ +KK K+K+ + + +
Sbjct: 156 EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDN--KKNRTKKKPT 213
Query: 62 PEPVVVATA------------IPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKK 109
P+P VV A P T T + + + T P+ + RP+ K
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI-NPRPSLPPNSDTSK 272
Query: 110 ETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ 169
ET L E E KET+ T+ T K+K A+ +++ + + P +
Sbjct: 273 ETSLTVNKETTVETKETTTTNKQTSTD-----GKEKTTSAKETQSIEKTSAKDLAPTS-- 325
Query: 170 GGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPL- 228
VL +P PK +T+ P + P +P + EP + + P+ P
Sbjct: 326 -KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK-EPTPTTIKSAPTTPKEPAP 383
Query: 229 -----GLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKS 283
P +P + PT E +E S P K
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 284 IPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMP- 342
P T P P P + + P + +K + P
Sbjct: 444 AP-------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496
Query: 343 DKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQA-IPSDSNPAVPTNPEHKT 401
+ T P E P P T A + A + S P P P T
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 402 PKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLA 461
K+ K+ + + +P T K +P PT P +P P
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTTP-KEPAP---T 611
Query: 462 TPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDL 521
TPK + + E+P T + + P PT P ++P P
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTP-EEPAP--- 666
Query: 522 ATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVE 574
TPK + K K + E + + A T + T L E
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.306 0.126 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,107,876,086
Number of Sequences: 2790947
Number of extensions: 55306901
Number of successful extensions: 256725
Number of sequences better than 10.0: 3958
Number of HSP's better than 10.0 without gapping: 297
Number of HSP's successfully gapped in prelim test: 3848
Number of HSP's that attempted gapping in prelim test: 214650
Number of HSP's gapped (non-prelim): 18874
length of query: 586
length of database: 848,049,833
effective HSP length: 133
effective length of query: 453
effective length of database: 476,853,882
effective search space: 216014808546
effective search space used: 216014808546
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 78 (34.7 bits)
Lotus: description of TM0148.5