BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0140.12
         (414 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_O22526 Cation-chloride co-transporter [Nicotiana tabacum]   687  0.0
UniRef100_Q9S9Q8 F26G16.3 protein [Arabidopsis thaliana]              670  0.0
UniRef100_Q6Z0E2 Putative Na+/K+/Cl-cotransport protein [Oryza s...   668  0.0
UniRef100_Q657W3 Putative potassium-chloride cotransporter isofo...   645  0.0
UniRef100_UPI0000362428 UPI0000362428 UniRef100 entry                 326  6e-88
UniRef100_UPI000035F577 UPI000035F577 UniRef100 entry                 325  1e-87
UniRef100_UPI000036196F UPI000036196F UniRef100 entry                 317  4e-85
UniRef100_UPI00003AA60F UPI00003AA60F UniRef100 entry                 304  3e-81
UniRef100_Q7YRU6 Potassium-chloride cotransporter isoform 4 [Ory...   295  2e-78
UniRef100_Q8MLQ5 CG5594-PD, isoform D [Drosophila melanogaster]       294  4e-78
UniRef100_Q8MKK5 GH09271p [Drosophila melanogaster]                   294  4e-78
UniRef100_Q9W1G6 CG5594-PA, isoform A [Drosophila melanogaster]       294  4e-78
UniRef100_Q9W1G5 CG5594-PC, isoform C [Drosophila melanogaster]       294  4e-78
UniRef100_UPI0000431822 UPI0000431822 UniRef100 entry                 293  8e-78
UniRef100_O18887 K-Cl cotransporter [Sus scrofa]                      286  7e-76
UniRef100_Q9N5M5 Hypothetical protein H16O14.1 [Caenorhabditis e...   234  3e-60
UniRef100_UPI0000195793 UPI0000195793 UniRef100 entry                 226  9e-58
UniRef100_UPI00002F096F UPI00002F096F UniRef100 entry                 211  2e-53
UniRef100_Q9UP95-2 Splice isoform 2 of Q9UP95 [Homo sapiens]          209  2e-52
UniRef100_Q9UP95-4 Splice isoform 4 of Q9UP95 [Homo sapiens]          209  2e-52

>UniRef100_O22526 Cation-chloride co-transporter [Nicotiana tabacum]
          Length = 990

 Score =  687 bits (1774), Expect = 0.0
 Identities = 330/404 (81%), Positives = 375/404 (92%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVGM GIG +LLLV  CG+CTFLT +SLSAIA+NGAMKGGGPYYLIGRALGPEVGVSIGL
Sbjct: 173 IVGMAGIGESLLLVVFCGSCTFLTTVSLSAIASNGAMKGGGPYYLIGRALGPEVGVSIGL 232

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYGI 130
           CFFLGNA+AGA+YVLGAVETFL AVP+AGIFRETIT+VNGT IA+PI SPS HDLQIYGI
Sbjct: 233 CFFLGNAIAGAMYVLGAVETFLNAVPSAGIFRETITRVNGTDIAEPITSPSLHDLQIYGI 292

Query: 131 VVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETLK 190
           VV+I+LCF+VFGGVKMINRVAPAFL+PVLFSL+CI++GI  AR D PA GITGL+LE+ K
Sbjct: 293 VVSILLCFVVFGGVKMINRVAPAFLVPVLFSLLCIFVGIFSARHDRPAVGITGLNLESFK 352

Query: 191 DNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQRSIPLG 250
           +NWGS YQ TN+AGIP+P+G + W+FNALVGLFFPAVTGIMAGSNRS+SLKDTQRSIP+G
Sbjct: 353 NNWGSSYQMTNNAGIPDPNGKIYWDFNALVGLFFPAVTGIMAGSNRSASLKDTQRSIPVG 412

Query: 251 TLAATLVTTFMYLVSVIMFGALATREKLLTDRLLTATVAWPFPSLIKIGIILSTMGAALQ 310
           TLAATL TT +Y+VSV++FGA++TR+KLLTDRLL+ATVAWP P+++ +GIILST+GAALQ
Sbjct: 413 TLAATLTTTGLYVVSVLLFGAVSTRDKLLTDRLLSATVAWPLPAIVYVGIILSTLGAALQ 472

Query: 311 SLTGAPRLLAAIANDDILPILKYFKVADGSEPHVATLFTAFLCSGCVVIGNLDLITPTVT 370
           SLTGAPRLLAAIANDDILP+L YFKVADG EPHVATLFTAF+C GCVVIGNLDL++PT T
Sbjct: 473 SLTGAPRLLAAIANDDILPVLNYFKVADGHEPHVATLFTAFICIGCVVIGNLDLVSPTST 532

Query: 371 MFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           MF+L+CYAGVNLS FLLDLLDAPSWRPRWKFHHW LSLVGALLC
Sbjct: 533 MFYLVCYAGVNLSSFLLDLLDAPSWRPRWKFHHWGLSLVGALLC 576


>UniRef100_Q9S9Q8 F26G16.3 protein [Arabidopsis thaliana]
          Length = 973

 Score =  670 bits (1729), Expect = 0.0
 Identities = 326/404 (80%), Positives = 364/404 (89%), Gaps = 2/404 (0%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVGM GIG  L+LV LCG CTFLT ISLSAIATNGAMKGGGPYYLIGRALGPEVG+SIGL
Sbjct: 158 IVGMAGIGQGLVLVFLCGLCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGISIGL 217

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYGI 130
           CFFLGNAVAGALYVLGAVETFLKA PAAGIFR       GT++++ I+SP+SHDLQ+YGI
Sbjct: 218 CFFLGNAVAGALYVLGAVETFLKAFPAAGIFRGI--SYCGTSVSESIQSPNSHDLQVYGI 275

Query: 131 VVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETLK 190
           VVTI+LCFIVFGGVKMINRVAPAFL+PVL S+ CI++GI LA+ D P  GITGL L++ K
Sbjct: 276 VVTILLCFIVFGGVKMINRVAPAFLVPVLLSIFCIFIGIFLAKTDDPDNGITGLRLKSFK 335

Query: 191 DNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQRSIPLG 250
           DNWGS YQ TNDAGIP+P G   W+FN LVGLFFPAVTGIMAGSNRS+SLKDTQ+SIP+G
Sbjct: 336 DNWGSAYQMTNDAGIPDPTGGTYWSFNELVGLFFPAVTGIMAGSNRSASLKDTQKSIPVG 395

Query: 251 TLAATLVTTFMYLVSVIMFGALATREKLLTDRLLTATVAWPFPSLIKIGIILSTMGAALQ 310
           TLAATL TT +YL+SV+ FGA+ATR+KLLTDRLLTAT+AWPFP+++ +GIILST+GAALQ
Sbjct: 396 TLAATLTTTSLYLISVLFFGAVATRDKLLTDRLLTATIAWPFPAIVHVGIILSTLGAALQ 455

Query: 311 SLTGAPRLLAAIANDDILPILKYFKVADGSEPHVATLFTAFLCSGCVVIGNLDLITPTVT 370
           SLTGAPRLLAAIANDDILPIL YFKVAD SEPH+ATLFTAF+C GCVVIGNLDLITPTVT
Sbjct: 456 SLTGAPRLLAAIANDDILPILNYFKVADTSEPHIATLFTAFICIGCVVIGNLDLITPTVT 515

Query: 371 MFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           MF+LLCY+GVNLSCFLLDLLDAPSWRPRWK+HHWSLS VGA LC
Sbjct: 516 MFYLLCYSGVNLSCFLLDLLDAPSWRPRWKYHHWSLSFVGASLC 559


>UniRef100_Q6Z0E2 Putative Na+/K+/Cl-cotransport protein [Oryza sativa]
          Length = 989

 Score =  668 bits (1723), Expect = 0.0
 Identities = 324/411 (78%), Positives = 370/411 (89%), Gaps = 7/411 (1%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVGM G+  +L+LV+ CG CTFLT ISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL
Sbjct: 158 IVGMAGVWQSLVLVSFCGACTFLTGISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 217

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVPAAGIFRETITQVNGTTI-------AQPIESPSSH 123
           CFFLGNAVAG++YVLGAVETFL AVP+AG F+E++T VN T +          I +PS H
Sbjct: 218 CFFLGNAVAGSMYVLGAVETFLDAVPSAGFFKESVTVVNNTLVNGTATASTATISTPSLH 277

Query: 124 DLQIYGIVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITG 183
           DLQ+YG++VTI+LCFIVFGGVK+IN+VAPAFLIPVLFSL+CIYLG+ +A   +  +GITG
Sbjct: 278 DLQVYGVIVTILLCFIVFGGVKIINKVAPAFLIPVLFSLLCIYLGVFIAPRHNAPKGITG 337

Query: 184 LSLETLKDNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDT 243
           LS+ T KDNWGSEYQ+TN+AG+P+P+GS+ W+FNALVGLFFPAVTGIMAGSNRS+SLKDT
Sbjct: 338 LSITTFKDNWGSEYQRTNNAGVPDPNGSIYWDFNALVGLFFPAVTGIMAGSNRSASLKDT 397

Query: 244 QRSIPLGTLAATLVTTFMYLVSVIMFGALATREKLLTDRLLTATVAWPFPSLIKIGIILS 303
           QRSIP+GTL+ATL TT MYL SV++FGALATRE+LLTDRLLTATVAWP P++I IGIILS
Sbjct: 398 QRSIPIGTLSATLTTTAMYLFSVLLFGALATREELLTDRLLTATVAWPAPAVIYIGIILS 457

Query: 304 TMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGSEPHVATLFTAFLCSGCVVIGNLD 363
           T+GAALQSLTGAPRLLAAIANDDILP+L YFKV++G+EPH ATLFTAF+C  CVVIGNLD
Sbjct: 458 TLGAALQSLTGAPRLLAAIANDDILPVLNYFKVSEGAEPHSATLFTAFICICCVVIGNLD 517

Query: 364 LITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           LITPT+TMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC
Sbjct: 518 LITPTITMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 568


>UniRef100_Q657W3 Putative potassium-chloride cotransporter isoform 4 [Oryza sativa]
          Length = 914

 Score =  645 bits (1664), Expect = 0.0
 Identities = 310/411 (75%), Positives = 364/411 (88%), Gaps = 7/411 (1%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVGMGG+  +L+LVA CG+CTFLT ISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL
Sbjct: 85  IVGMGGVWQSLVLVAFCGSCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 144

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVPAAGIFRETITQVNGTTI-------AQPIESPSSH 123
           CFFLGNAVAGA+YVLGAVETFL AVP+A  F+E++T V  T +       A  I +P+ H
Sbjct: 145 CFFLGNAVAGAMYVLGAVETFLDAVPSAEFFQESVTVVTNTFVNGTAAGNATTISTPNLH 204

Query: 124 DLQIYGIVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITG 183
           DLQ+YGI+VTI+LCFIVFGGVK+IN+VAPAFLIPVLFS++CIY+G+ +A   + ++ ITG
Sbjct: 205 DLQVYGIIVTILLCFIVFGGVKIINKVAPAFLIPVLFSILCIYIGVFIAPRPNASKWITG 264

Query: 184 LSLETLKDNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDT 243
           LS+ TLKDNW S+YQ+TN+AG+P+P+GS+ W+FNAL+GL+FPAVTGIMAGSNRS+SLKDT
Sbjct: 265 LSITTLKDNWSSDYQRTNNAGVPDPNGSIYWDFNALLGLYFPAVTGIMAGSNRSASLKDT 324

Query: 244 QRSIPLGTLAATLVTTFMYLVSVIMFGALATREKLLTDRLLTATVAWPFPSLIKIGIILS 303
           QRSIP+GTL AT+ TT MYL+SV +FGAL+TRE LLTDRLL A VAWP P+++  GIILS
Sbjct: 325 QRSIPIGTLHATISTTMMYLLSVFLFGALSTREGLLTDRLLCAAVAWPSPAVVYAGIILS 384

Query: 304 TMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGSEPHVATLFTAFLCSGCVVIGNLD 363
           T+GAALQSLTGAPRLLAAIANDDILP+L YFK  +GSEPHVATLFT+F+C  CV+IGNLD
Sbjct: 385 TLGAALQSLTGAPRLLAAIANDDILPVLNYFKAYEGSEPHVATLFTSFICISCVIIGNLD 444

Query: 364 LITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           +ITPT+TMFFLLCYAGVNLSCFLLDLLDAPSWRPRWK HHWSLSL+GALLC
Sbjct: 445 VITPTITMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKLHHWSLSLIGALLC 495


>UniRef100_UPI0000362428 UPI0000362428 UniRef100 entry
          Length = 845

 Score =  326 bits (836), Expect = 6e-88
 Identities = 177/413 (42%), Positives = 262/413 (62%), Gaps = 27/413 (6%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVGM GI  +LL+V +C +CT LTAIS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 27  IVGMAGIMQSLLIVLMCCSCTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 86

Query: 71  CFFLGNAVAGALYVLGAVETFLK-AVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   A A+Y+LGA+E FLK  VP A IF    T  +GT      +S   +++++YG
Sbjct: 87  CFYLGTTFASAMYILGAIEIFLKYLVPQAAIFH--ATDPHGT------DSAMLNNMRVYG 138

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
            +   ++  +VF GVK +N++A  FL  V+ S++ IY G   +    P         E  
Sbjct: 139 SICLSLMAVVVFVGVKYVNKLASLFLTCVIISIVSIYAGAFKSLTHPP---------EFP 189

Query: 190 KDNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQRSIPL 249
           K ++ + +  T + G+      ++ +F  LVG+FFP+ TGIMAGSNRS  L+D Q++IP+
Sbjct: 190 KQDFVNGHGATENFGM-YVSADIATSFTVLVGIFFPSATGIMAGSNRSGDLRDAQKAIPV 248

Query: 250 GTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKIGIIL 302
           GT+ A   T+ +YL SV++FG+    +  R+K    ++  L+  T++WP P +I IG   
Sbjct: 249 GTILAITTTSLVYLSSVVLFGSCIEGVVLRDKFGDAVSKTLVVGTLSWPSPWVIVIGSFF 308

Query: 303 STMGAALQSLTGAPRLLAAIANDDILPILKYF-KVADGSEPHVATLFTAFLCSGCVVIGN 361
           ST+GA LQSLTGAPRLL AIA D+I+P L+ F       EP  A L T  +    ++I +
Sbjct: 309 STVGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKTNGEPTWALLLTGLIAELGILIAS 368

Query: 362 LDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           LD++ P ++MFFL+CY  VNL+C +  LL  P+WRPR++++HW+LS +G  +C
Sbjct: 369 LDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFRYYHWALSFLGMSMC 421


>UniRef100_UPI000035F577 UPI000035F577 UniRef100 entry
          Length = 723

 Score =  325 bits (834), Expect = 1e-87
 Identities = 184/424 (43%), Positives = 260/424 (60%), Gaps = 42/424 (9%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG+GG+ GT ++V +C T T LTAIS+SAIATNG +  GG YY+I R+LGPE G ++G+
Sbjct: 30  LVGIGGVIGTFIIVTMCCTTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGI 89

Query: 71  CFFLGNAVAGALYVLGAVETFL-KAVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   AGA+Y+LGA+E  L   VP A IF      + G   A+  E+   +++++YG
Sbjct: 90  CFYLGTTYAGAMYILGAIELLLIYIVPKAAIF-----PLEGLEGAE-AEAALLNNMRVYG 143

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
            ++   +  +VF GVK +N++A  FL  V+ S++ +Y           AE + G   E  
Sbjct: 144 TILLTSMATVVFVGVKYVNKLALVFLACVILSILAVY-----------AENLFGTYYEK- 191

Query: 190 KDNWGSEYQKTNDAGIPEPD-----------GSVSWNFNALVGLFFPAVTGIMAGSNRSS 238
               G    KT+ A + E D             ++  F  LVG++FP+VTGIMAGSNRS 
Sbjct: 192 ----GDLIAKTDMASVEEQDDPLTNANRFVLADITSFFTLLVGIYFPSVTGIMAGSNRSG 247

Query: 239 SLKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWP 291
            L+D Q+SIP+GT+AA   T+ +Y+ SV +FGA    +  R+K    +   L+  T+AWP
Sbjct: 248 DLRDAQKSIPIGTIAAITTTSTVYMSSVFLFGACIEGVVLRDKFGEGVHGNLVIGTLAWP 307

Query: 292 FPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGS-EPHVATLFTA 350
            P +I IG   ST GA LQSLTGAPRLL AIA D I+P L+ F     + EP  + L TA
Sbjct: 308 SPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDGIVPALRIFGHGKANGEPTWSLLLTA 367

Query: 351 FLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVG 410
            +C   ++I +LD + P ++MFFL+CY  VNL+C L  LL  P+WRPR+KF+HW+LS +G
Sbjct: 368 CICESGILIASLDAVAPILSMFFLMCYMFVNLACALQTLLRTPNWRPRFKFYHWTLSFLG 427

Query: 411 ALLC 414
             LC
Sbjct: 428 MSLC 431


>UniRef100_UPI000036196F UPI000036196F UniRef100 entry
          Length = 731

 Score =  317 bits (812), Expect = 4e-85
 Identities = 179/425 (42%), Positives = 261/425 (61%), Gaps = 34/425 (8%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG+GG+ G+ ++V +C + T LTAIS+SAIATNG +  GG YY+I R+LGPE G ++G+
Sbjct: 30  MVGIGGVFGSFIIVFMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGI 89

Query: 71  CFFLGNAVAGALYVLGAVETFL-KAVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   AGA+Y+LG +E  L   VP A IF+  I  + G       E+   +++++YG
Sbjct: 90  CFYLGTTFAGAMYILGCIEILLIYIVPQAAIFK--IEGLEG----PEAEAALLNNMRVYG 143

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
            +V   +  +VF GVK +N++A  FL  V+ S++ +Y G++    D P   I  L+   L
Sbjct: 144 TIVLSFMALVVFVGVKYVNKLALVFLACVILSIVAVYAGVIKTAVDPPVFPI-DLTAACL 202

Query: 190 KDNWGSEYQK----TNDAGIP---EPDG-----------SVSWNFNALVGLFFPAVTGIM 231
            +N   +Y +        G+P   +PDG            ++  F  LVG++FP+VTGIM
Sbjct: 203 VENLFGKYLEKGAILEKRGLPSDVDPDGPTTNSNRYVVADITSFFTLLVGIYFPSVTGIM 262

Query: 232 AGSNRSSSLKDTQRSIPLGTLAATLVTTFMYLVSV-IMFGALATREKLLTDRLLTATVAW 290
           AGSNRS  L+D Q+SIP+GT+AA   T+ + ++S   +FG      + +   L+  T+AW
Sbjct: 263 AGSNRSGDLRDAQKSIPIGTIAAITTTSTVCILSYPTLFG------EGVNGNLVIGTLAW 316

Query: 291 PFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGS-EPHVATLFT 349
           P P +I  G   ST GA LQSLTGAPRLL AI+ D I+P L+ F     + EP  A L T
Sbjct: 317 PSPWVIVFGSFFSTCGAGLQSLTGAPRLLQAISRDGIIPFLRVFGHGKANGEPTWALLLT 376

Query: 350 AFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLV 409
           A +C   ++I +LD + P ++MFFL+CY  VNL+C L  LL  P+WRPR+KF+HW+LS +
Sbjct: 377 AGICEIGIIIASLDAVAPILSMFFLMCYMFVNLACALQTLLRTPNWRPRFKFYHWALSFL 436

Query: 410 GALLC 414
           G  LC
Sbjct: 437 GMSLC 441


>UniRef100_UPI00003AA60F UPI00003AA60F UniRef100 entry
          Length = 733

 Score =  304 bits (778), Expect = 3e-81
 Identities = 179/434 (41%), Positives = 255/434 (58%), Gaps = 46/434 (10%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VGM G+  + L+V LC  CT LT IS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 29  MVGMAGVLQSFLIVLLCCCCTMLTTISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 88

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVP-----AAGIFRETI---TQVNGTTIAQPIESPSS 122
           CF+LG   AGA+Y+LGA+E  L +V      A  +F+  I     +   + A    S   
Sbjct: 89  CFYLGTTFAGAMYILGAIEILLSSVSVLLQLAFFLFQTYIVPQAAIFYPSGAHDASSAML 148

Query: 123 HDLQIYGIVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGIL------------ 170
           +++++YG V  I++  +VF GVK +N+ A  FL  V+ S++ IY G +            
Sbjct: 149 NNMRVYGTVFLILMAVVVFVGVKYVNKFASLFLACVVISILSIYAGAIKSIFDPPEFPNY 208

Query: 171 ------LAREDHPAEGITGLSLETLKDNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFF 224
                 L +  HP+  + G              QK+N       D  +S +F  LVG+FF
Sbjct: 209 LEKGEVLEKAHHPSVDVAG--------------QKSNFHLYVLSD--ISTSFMVLVGIFF 252

Query: 225 PAVTGIMAGSNRSSSLKDTQRSIPLGTLAATLVTTFM-YLVSVIMFGALA--TREKLLTD 281
           P+VTGIMAGSNRS  LKD Q+SIP+GT+ A + T+ +  L+  I    +A  + E LL  
Sbjct: 253 PSVTGIMAGSNRSGDLKDAQKSIPVGTILAIVTTSLVCILLKSIQSYCIASDSDECLLNK 312

Query: 282 RLLTATVAWPFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGS- 340
            L+  T++WP P +I IG   ST GA LQSLTGAPRLL AIA D+I+P L  F     + 
Sbjct: 313 NLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLWVFGHGKANG 372

Query: 341 EPHVATLFTAFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWK 400
           EP  A L TA +    ++I +LD++ P ++MFFL+CY  VNL+C +  LL  P+WRPR+K
Sbjct: 373 EPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFK 432

Query: 401 FHHWSLSLVGALLC 414
           ++HW+LS +G  +C
Sbjct: 433 YYHWALSFLGMSIC 446


>UniRef100_Q7YRU6 Potassium-chloride cotransporter isoform 4 [Oryctolagus cuniculus]
          Length = 1106

 Score =  295 bits (755), Expect = 2e-78
 Identities = 178/483 (36%), Positives = 257/483 (52%), Gaps = 79/483 (16%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVG  G+  + L+V++C TCT LTA+S+SAIATNG +  GG YY+I R+LGPE G ++GL
Sbjct: 168 IVGAAGVLESFLVVSMCCTCTMLTAVSMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGL 227

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   AGA+Y+LG +E FL  + P A +F+    +     +   +    S  L +  
Sbjct: 228 CFYLGTTFAGAMYILGTIEIFLTYISPGAAVFQAETPEGEAAALLHNMRVYGSCTLALMA 287

Query: 130 IVVTIVLCFI-----------------VFGGV---------------------------- 144
           +VV + + ++                 ++ GV                            
Sbjct: 288 VVVFVGVKYVNKLALVFLACVVLSILAIYAGVIKTAFDPPDIPVCLLGNRTLARRGFDTC 347

Query: 145 KMINRVAPAFLIPVLFSLICIYLGILLAREDHPAE-------GITGLSLETLKDNWGSEY 197
             +  V+       L+ L C    +  A  ++ A+       GI G++   L DN  S Y
Sbjct: 348 AKVRAVSNGTATTALWGLFCNGSSLDTACNEYFAQNNVTEIQGIPGVASGVLLDNLWSAY 407

Query: 198 -------QKTNDAGIPEPD-----------GSVSWNFNALVGLFFPAVTGIMAGSNRSSS 239
                  +K   A +P P+             ++  F  LVG++FP+VTGIMAGSNRS  
Sbjct: 408 SDRGAFVEKKGVASVPTPEDGRASGLPYVLSDITTYFTVLVGIYFPSVTGIMAGSNRSGD 467

Query: 240 LKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPF 292
           LKD Q+SIP GT+ A + T+F+YL  +++FGA    +  R+K    L   L+   +AWP 
Sbjct: 468 LKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPS 527

Query: 293 PSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGS-EPHVATLFTAF 351
           P +I IG   ST GA LQSLTGAPRLL AIA D I+P L+ F     + EP  A L TA 
Sbjct: 528 PWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTAL 587

Query: 352 LCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGA 411
           +C   ++I +LD + P ++MFFL+CY  VNL+C +  LL  P+WRPR+K++HW+LS +G 
Sbjct: 588 ICETGILIASLDSVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKYYHWTLSFLGM 647

Query: 412 LLC 414
            LC
Sbjct: 648 SLC 650


>UniRef100_Q8MLQ5 CG5594-PD, isoform D [Drosophila melanogaster]
          Length = 1074

 Score =  294 bits (752), Expect = 4e-78
 Identities = 180/477 (37%), Positives = 255/477 (52%), Gaps = 83/477 (17%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G     L+V  C   T LTAIS+SAIATNG +  GG Y++I R+LGPE G ++G+
Sbjct: 135 VVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGM 194

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
            F+ G  +A A+Y++GAVE  L  + P A IF +     +             ++ ++YG
Sbjct: 195 LFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMY----------NNFRVYG 244

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGIL------------------- 170
            ++ I +  IVF GVK +N+ A   L  V+ S+I +Y+GI                    
Sbjct: 245 TLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLL 304

Query: 171 -----------------------------LAREDHPAEGITGLSLETLKDN--------- 192
                                        LA      +GI GL+     DN         
Sbjct: 305 KDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKG 364

Query: 193 ----WGS---EYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQR 245
               +G    + + T+     +    ++ +F  L+G+FFP+VTGIMAGSNRS  L D Q+
Sbjct: 365 QFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQK 424

Query: 246 SIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKI 298
           SIP+GT+ A L T+ +YL SV+ F      L  R+K    +  +L+ A +AWP   +I I
Sbjct: 425 SIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILI 484

Query: 299 GIILSTMGAALQSLTGAPRLLAAIANDDILPILKYF-KVADGSEPHVATLFTAFLCSGCV 357
           G  LST+GA LQSLTGAPRLL AIA D+I+P L  F K +   EP  A L T  +C   +
Sbjct: 485 GSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGI 544

Query: 358 VIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++GN+DL+ P ++MFFL+CY  VNL+C +  LL  P+WRPR+KF+HWSLSL+G  LC
Sbjct: 545 LLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLC 601


>UniRef100_Q8MKK5 GH09271p [Drosophila melanogaster]
          Length = 1028

 Score =  294 bits (752), Expect = 4e-78
 Identities = 180/477 (37%), Positives = 255/477 (52%), Gaps = 83/477 (17%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G     L+V  C   T LTAIS+SAIATNG +  GG Y++I R+LGPE G ++G+
Sbjct: 120 VVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGM 179

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
            F+ G  +A A+Y++GAVE  L  + P A IF +     +             ++ ++YG
Sbjct: 180 LFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMY----------NNFRVYG 229

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGIL------------------- 170
            ++ I +  IVF GVK +N+ A   L  V+ S+I +Y+GI                    
Sbjct: 230 TLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLL 289

Query: 171 -----------------------------LAREDHPAEGITGLSLETLKDN--------- 192
                                        LA      +GI GL+     DN         
Sbjct: 290 KDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKG 349

Query: 193 ----WGS---EYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQR 245
               +G    + + T+     +    ++ +F  L+G+FFP+VTGIMAGSNRS  L D Q+
Sbjct: 350 QFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQK 409

Query: 246 SIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKI 298
           SIP+GT+ A L T+ +YL SV+ F      L  R+K    +  +L+ A +AWP   +I I
Sbjct: 410 SIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILI 469

Query: 299 GIILSTMGAALQSLTGAPRLLAAIANDDILPILKYF-KVADGSEPHVATLFTAFLCSGCV 357
           G  LST+GA LQSLTGAPRLL AIA D+I+P L  F K +   EP  A L T  +C   +
Sbjct: 470 GSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGI 529

Query: 358 VIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++GN+DL+ P ++MFFL+CY  VNL+C +  LL  P+WRPR+KF+HWSLSL+G  LC
Sbjct: 530 LLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLC 586


>UniRef100_Q9W1G6 CG5594-PA, isoform A [Drosophila melanogaster]
          Length = 1043

 Score =  294 bits (752), Expect = 4e-78
 Identities = 180/477 (37%), Positives = 255/477 (52%), Gaps = 83/477 (17%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G     L+V  C   T LTAIS+SAIATNG +  GG Y++I R+LGPE G ++G+
Sbjct: 135 VVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGM 194

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
            F+ G  +A A+Y++GAVE  L  + P A IF +     +             ++ ++YG
Sbjct: 195 LFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMY----------NNFRVYG 244

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGIL------------------- 170
            ++ I +  IVF GVK +N+ A   L  V+ S+I +Y+GI                    
Sbjct: 245 TLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLL 304

Query: 171 -----------------------------LAREDHPAEGITGLSLETLKDN--------- 192
                                        LA      +GI GL+     DN         
Sbjct: 305 KDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKG 364

Query: 193 ----WGS---EYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQR 245
               +G    + + T+     +    ++ +F  L+G+FFP+VTGIMAGSNRS  L D Q+
Sbjct: 365 QFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQK 424

Query: 246 SIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKI 298
           SIP+GT+ A L T+ +YL SV+ F      L  R+K    +  +L+ A +AWP   +I I
Sbjct: 425 SIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILI 484

Query: 299 GIILSTMGAALQSLTGAPRLLAAIANDDILPILKYF-KVADGSEPHVATLFTAFLCSGCV 357
           G  LST+GA LQSLTGAPRLL AIA D+I+P L  F K +   EP  A L T  +C   +
Sbjct: 485 GSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGI 544

Query: 358 VIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++GN+DL+ P ++MFFL+CY  VNL+C +  LL  P+WRPR+KF+HWSLSL+G  LC
Sbjct: 545 LLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLC 601


>UniRef100_Q9W1G5 CG5594-PC, isoform C [Drosophila melanogaster]
          Length = 1059

 Score =  294 bits (752), Expect = 4e-78
 Identities = 180/477 (37%), Positives = 255/477 (52%), Gaps = 83/477 (17%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G     L+V  C   T LTAIS+SAIATNG +  GG Y++I R+LGPE G ++G+
Sbjct: 120 VVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGM 179

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
            F+ G  +A A+Y++GAVE  L  + P A IF +     +             ++ ++YG
Sbjct: 180 LFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMY----------NNFRVYG 229

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGIL------------------- 170
            ++ I +  IVF GVK +N+ A   L  V+ S+I +Y+GI                    
Sbjct: 230 TLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLL 289

Query: 171 -----------------------------LAREDHPAEGITGLSLETLKDN--------- 192
                                        LA      +GI GL+     DN         
Sbjct: 290 KDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKG 349

Query: 193 ----WGS---EYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQR 245
               +G    + + T+     +    ++ +F  L+G+FFP+VTGIMAGSNRS  L D Q+
Sbjct: 350 QFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQK 409

Query: 246 SIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKI 298
           SIP+GT+ A L T+ +YL SV+ F      L  R+K    +  +L+ A +AWP   +I I
Sbjct: 410 SIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILI 469

Query: 299 GIILSTMGAALQSLTGAPRLLAAIANDDILPILKYF-KVADGSEPHVATLFTAFLCSGCV 357
           G  LST+GA LQSLTGAPRLL AIA D+I+P L  F K +   EP  A L T  +C   +
Sbjct: 470 GSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGI 529

Query: 358 VIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++GN+DL+ P ++MFFL+CY  VNL+C +  LL  P+WRPR+KF+HWSLSL+G  LC
Sbjct: 530 LLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLC 586


>UniRef100_UPI0000431822 UPI0000431822 UniRef100 entry
          Length = 722

 Score =  293 bits (749), Expect = 8e-78
 Identities = 163/413 (39%), Positives = 240/413 (57%), Gaps = 19/413 (4%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G      +V  C   T LTAIS+SAIATNG +  GG Y++I R+LGPE G ++G+
Sbjct: 34  VVGTAGAFQGFFIVLCCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGM 93

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
            F+ G  +A A+Y++GAVE  L  + P+  IF +     N             ++ ++YG
Sbjct: 94  LFYTGTTLAAAMYIIGAVEIVLTYMAPSLSIFGDFTKDPN----------IMYNNFRVYG 143

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
             + +V+  IVF GVK +N+ A   L  V+ S++ +Y+G+      + +           
Sbjct: 144 TGLLMVMGTIVFIGVKFVNKFATVALACVILSIVAVYVGLFYNFNGNESLNFQEEGQLIA 203

Query: 190 KDNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQRSIPL 249
                 +    +++   +    ++  F  L+G+FFP+VTGIMAGSNRS  L D Q+SIP+
Sbjct: 204 YGRDPKDIDMMSNSSFNQIQVDLTTTFTILIGIFFPSVTGIMAGSNRSGDLADAQKSIPI 263

Query: 250 GTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLLTATVAWPFPSLIKIGIIL 302
           GT+ A L T+ +YL SV++F      L  R+K    +  +L+ A +AWP   +I IG  L
Sbjct: 264 GTICAILTTSTVYLSSVLLFAGTVDNLLLRDKFGQSIGGKLVVANMAWPNQWVILIGSFL 323

Query: 303 STMGAALQSLTGAPRLLAAIANDDILPILKYFKVADG-SEPHVATLFTAFLCSGCVVIGN 361
           ST+GA LQSLTGAPRLL AIA D I+P L  F  +    EP  A + T  +C   +++GN
Sbjct: 324 STLGAGLQSLTGAPRLLQAIAKDSIIPFLTPFATSSSRGEPTRALVLTVIICQCGILLGN 383

Query: 362 LDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           +D + P ++MFFL+CY  VNL+C L  LL  P+WRPR+K++HWSLS +G  LC
Sbjct: 384 VDYLAPLLSMFFLMCYGFVNLACALQTLLRTPNWRPRFKYYHWSLSFLGLSLC 436


>UniRef100_O18887 K-Cl cotransporter [Sus scrofa]
          Length = 1086

 Score =  286 bits (732), Expect = 7e-76
 Identities = 182/491 (37%), Positives = 257/491 (52%), Gaps = 95/491 (19%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G+   LL+V +C  CT LTAIS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 144 MVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 203

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   A A+Y+LGA+E  L  + P A IF  T T            S + +++++YG
Sbjct: 204 CFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPTGTH--------DTSSATLNNMRVYG 255

Query: 130 IV--------------------------VTIVLCFIVFGGVKMI------------NRVA 151
            +                          V I +  I  GG+K I            NR  
Sbjct: 256 TIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTL 315

Query: 152 PAFLIPV---------------LFSLICIYLGI--------LLAREDHPAEGITGLSLET 188
                 V               L+SL C    +         L        GI G +   
Sbjct: 316 SRDQFDVCAKTVMVDNETVTTRLWSLFCHSPNLTADSCDPYFLLNNVTEIPGIPGAAASV 375

Query: 189 LKDNWGSEYQKTNDA----GIPEPDG-------------SVSWNFNALVGLFFPAVTGIM 231
           L++N  S Y +  +     G+P  D               ++ +F  LVG+FFP+VTGIM
Sbjct: 376 LQENLWSAYLEKGEVVEKHGLPSTDALGLKESLPLYVVADIATSFTVLVGIFFPSVTGIM 435

Query: 232 AGSNRSSSLKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL---LTDRLL 284
           AGSNRS  L+D Q+SIP+GT+ A + T+ +Y  SV++FGA    +  R+K    ++  L+
Sbjct: 436 AGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLV 495

Query: 285 TATVAWPFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADGS-EPH 343
             T+AWP P +I IG   ST GA LQSLTGAPRLL AIA D+I+P L+ F     + EP 
Sbjct: 496 VGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPT 555

Query: 344 VATLFTAFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHH 403
            A L TA +    ++I +LD++ P ++MFFL+CY  VNL+C +  LL  P+WRPR+K++H
Sbjct: 556 WALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYH 615

Query: 404 WSLSLVGALLC 414
           W+LS +G  LC
Sbjct: 616 WALSFLGMSLC 626


>UniRef100_Q9N5M5 Hypothetical protein H16O14.1 [Caenorhabditis elegans]
          Length = 977

 Score =  234 bits (598), Expect = 3e-60
 Identities = 164/478 (34%), Positives = 235/478 (48%), Gaps = 75/478 (15%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLI----GRALGPEV-- 64
           I+G  G+     +V  C + TFLT+ISLSAIATNG +  GGPYY+I    G  LG  V  
Sbjct: 27  IIGTAGVFQAFFVVLTCVSVTFLTSISLSAIATNGVVPSGGPYYMISRNLGPELGGAVGI 86

Query: 65  ----GVSIGLCFFLGNAVAGAL-YVLGAVETFLKAVPAAGIFRETITQVNGTTIAQPIES 119
               G +I    ++  A+   L Y+    + F        +    +  + G  +   ++ 
Sbjct: 87  LFYLGTTIAASMYITGAIEILLLYIYPQAKLFDDIYHNFRVLGTVLLLILGLIVMAGVKF 146

Query: 120 PSSHDLQIYGIVVTIVLC-----FIVFGGVKMIN------------------RVAPAFLI 156
            +   L +  +V+  +L      F+ + G   +                   +V P    
Sbjct: 147 VNRCALPLVIVVILCILSAILGVFVRYDGSDSLKFCMVGDRPVDLSTYFEKTQVQPNCTA 206

Query: 157 PVLFSLICIYLGILLAREDH------------PA----EGITGLSLETLKDNWGSEYQKT 200
             L  L C   G      D             PA      I G++     DN   +Y + 
Sbjct: 207 DGLQDLFCSTNGTCDHYYDRMKNIKVWKSSGMPAIREERAIKGIASGVFFDNLWPKYLRA 266

Query: 201 N--------DAGIPEPDGSVSW-------NFNALVGLFFPAVTGIMAGSNRSSSLKDTQR 245
                    D G     G  S+       NF  LVG+FFP+ TGIMAGSNRS +L+D  +
Sbjct: 267 GEVLSKDRKDKGDLNRGGHPSYIYAESVTNFMILVGVFFPSATGIMAGSNRSGNLRDAAK 326

Query: 246 SIPLGTLAATLVTTFMYLVSVIMFGALATREKLLTDR--------LLTATVAWPFPSLIK 297
           SIPLGTLAA   ++F+YL+ V++FGA +  E  + D+        L+ + ++WPFP +I 
Sbjct: 327 SIPLGTLAAQNFSSFIYLLGVVLFGA-SVSEMFIRDKYGRSAMGKLIISEISWPFPQVIL 385

Query: 298 IGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADG-SEPHVATLFTAFLCSGC 356
            G  +ST GA +QSLTGAPRLL AIA DD+LP LK F+  D   EP  A L T  +C   
Sbjct: 386 FGCFMSTAGAGMQSLTGAPRLLQAIAADDVLPFLKPFRKMDSRGEPIRAILLTLAICECG 445

Query: 357 VVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++I  ++ IT  +T FFL+CY GVN +C L  LL +P WRP +++ HWSLS++GA+LC
Sbjct: 446 ILIAVIENITALITQFFLMCYLGVNAACALQSLLKSPGWRPGFRYFHWSLSMIGAILC 503


>UniRef100_UPI0000195793 UPI0000195793 UniRef100 entry
          Length = 823

 Score =  226 bits (576), Expect = 9e-58
 Identities = 139/418 (33%), Positives = 220/418 (52%), Gaps = 43/418 (10%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           IVG  GIG +++++A+    T +T +S SAIATNG ++GGG YYLI R+LGPE G +IGL
Sbjct: 19  IVGQAGIGLSVVVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGL 78

Query: 71  CFFLGNAVAGALYVLGAVETFLKAVPAAGIFRETITQVNGTTIAQPIESPSSHDLQIYGI 130
            F   NAVA A+YV+G  ET ++ +    I    I ++N              D++I G 
Sbjct: 79  IFAFANAVAVAMYVVGFAETVVELLKEHSIL--MIDEIN--------------DIRIIGA 122

Query: 131 VVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETLK 190
           +  ++L  I   G++   +     L+ +L ++    +G  ++ E    +G  G   E   
Sbjct: 123 ITVVILLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLESKKPKGFFGYKSEIFN 182

Query: 191 DNWGSEYQKTNDAGIPEPDGSVSWNFNALVGLFFPAVTGIMAGSNRSSSLKDTQRSIPLG 250
           +N+G ++++                F ++  +FFPA TGI+AG+N S  L D Q +IP G
Sbjct: 183 ENFGPDFREEE-------------TFFSVFAIFFPAATGILAGANISGDLADPQSAIPKG 229

Query: 251 TLAATLVTTFMYL---VSVIMFGALATREKLLTDR---------LLTATVAWPFPSLIKI 298
           TL A L+TT +Y+   VSV  F  +++   L T               ++   F  LI  
Sbjct: 230 TLLAILITTVVYIGIAVSVDSFQIISSFPLLETSHCDYALFCHFFKVMSMVSGFAPLISA 289

Query: 299 GIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFKVADG--SEPHVATLFTAFLCSGC 356
           GI  +T+ +AL SL  AP++  A+  D+I P  + F    G  +EP    + T  +  G 
Sbjct: 290 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGF 349

Query: 357 VVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKFHHWSLSLVGALLC 414
           ++I  L++I P ++ FFL  YA +N S F   L  +P WRP +K+++  +SL+GA+LC
Sbjct: 350 ILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLIGAILC 407


>UniRef100_UPI00002F096F UPI00002F096F UniRef100 entry
          Length = 1211

 Score =  211 bits (538), Expect = 2e-53
 Identities = 116/261 (44%), Positives = 160/261 (60%), Gaps = 25/261 (9%)

Query: 179 EGITGLSLETLKDNWGSEYQKTND--------AGIPEPDGS---------VSWNFNALVG 221
           +GI GL+   + +N  S Y    +        A    P  S         ++ +F  LVG
Sbjct: 448 QGIPGLASSIISENLWSSYLSKGEVVEKGSIQASDEAPPASTHHPYVFADITTSFTLLVG 507

Query: 222 LFFPAVTGIMAGSNRSSSLKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREK 277
           +FFP+VTGIMAGSNRS  LKD QRSIP+GT+ A L T+ +YL SV++FGA    +  R+K
Sbjct: 508 IFFPSVTGIMAGSNRSGDLKDAQRSIPIGTILAILTTSIVYLSSVVLFGACIDGVVLRDK 567

Query: 278 L---LTDRLLTATVAWPFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYF 334
               +   L+  T+AWP P +I +G   ST GA LQSLTGAPRLL AIA D+++P L+ F
Sbjct: 568 FGDSVKGNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNVIPFLRVF 627

Query: 335 KVADGS-EPHVATLFTAFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAP 393
                + EP  A L TA +    ++I +LDL+ P +TMFFL+CY  VNL+C L  LL  P
Sbjct: 628 GHGKANGEPTWALLLTALIAELGILIASLDLVAPILTMFFLMCYLFVNLACALQTLLRTP 687

Query: 394 SWRPRWKFHHWSLSLVGALLC 414
           +WRPR+ ++HW+LS +G ++C
Sbjct: 688 NWRPRFSYYHWTLSFLGMMIC 708



 Score =  133 bits (335), Expect = 8e-30
 Identities = 67/163 (41%), Positives = 103/163 (63%), Gaps = 9/163 (5%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G+   L +V +C  CT LTAIS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 197 VVGNAGVLQGLCIVFICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 256

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   AGA+Y+LGA+E  L  + P A IF     +  G  +         +++++YG
Sbjct: 257 CFYLGTTFAGAMYILGAIEILLMYIAPKAAIFEPKHPEGEGAAML--------NNMRVYG 308

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLA 172
            +  +++  +VF GVK +N++A  FL  V+ S++ IY G L++
Sbjct: 309 SICLLLMSLLVFVGVKYVNKLASIFLACVIISIVSIYAGALVS 351


>UniRef100_Q9UP95-2 Splice isoform 2 of Q9UP95 [Homo sapiens]
          Length = 1068

 Score =  209 bits (531), Expect = 2e-52
 Identities = 114/260 (43%), Positives = 160/260 (60%), Gaps = 25/260 (9%)

Query: 180 GITGLSLETLKDNWGSEYQKTNDA----GIPEPDG-------------SVSWNFNALVGL 222
           GI G +   L++N  S Y +  D     G+P  D               ++ +F  LVG+
Sbjct: 367 GIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGI 426

Query: 223 FFPAVTGIMAGSNRSSSLKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL 278
           FFP+VTGIMAGSNRS  L+D Q+SIP+GT+ A + T+ +Y  SV++FGA    +  R+K 
Sbjct: 427 FFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKY 486

Query: 279 ---LTDRLLTATVAWPFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFK 335
              ++  L+  T+AWP P +I IG   ST GA LQSLTGAPRLL AIA D+I+P L+ F 
Sbjct: 487 GDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFG 546

Query: 336 VAD-GSEPHVATLFTAFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPS 394
                 EP  A L TA +    ++I +LD++ P ++MFFL+CY  VNL+C +  LL  P+
Sbjct: 547 HGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPN 606

Query: 395 WRPRWKFHHWSLSLVGALLC 414
           WRPR+K++HW+LS +G  LC
Sbjct: 607 WRPRFKYYHWALSFLGMSLC 626



 Score =  130 bits (327), Expect = 7e-29
 Identities = 71/180 (39%), Positives = 106/180 (58%), Gaps = 9/180 (5%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G+   LL+V +C  CT LTAIS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 144 MVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 203

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   A A+Y+LGA+E  L  + P A IF          + A    + + +++++YG
Sbjct: 204 CFYLGTTFAAAMYILGAIEILLTYIAPPAAIFY--------PSGAHDTSNATLNNMRVYG 255

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
            +    +  +VF GVK +N+ A  FL  V+ S++ IY G + +  D P   +  L   TL
Sbjct: 256 TIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTL 315


>UniRef100_Q9UP95-4 Splice isoform 4 of Q9UP95 [Homo sapiens]
          Length = 780

 Score =  209 bits (531), Expect = 2e-52
 Identities = 114/260 (43%), Positives = 160/260 (60%), Gaps = 25/260 (9%)

Query: 180 GITGLSLETLKDNWGSEYQKTNDA----GIPEPDG-------------SVSWNFNALVGL 222
           GI G +   L++N  S Y +  D     G+P  D               ++ +F  LVG+
Sbjct: 367 GIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGI 426

Query: 223 FFPAVTGIMAGSNRSSSLKDTQRSIPLGTLAATLVTTFMYLVSVIMFGA----LATREKL 278
           FFP+VTGIMAGSNRS  L+D Q+SIP+GT+ A + T+ +Y  SV++FGA    +  R+K 
Sbjct: 427 FFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKY 486

Query: 279 ---LTDRLLTATVAWPFPSLIKIGIILSTMGAALQSLTGAPRLLAAIANDDILPILKYFK 335
              ++  L+  T+AWP P +I IG   ST GA LQSLTGAPRLL AIA D+I+P L+ F 
Sbjct: 487 GDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFG 546

Query: 336 VAD-GSEPHVATLFTAFLCSGCVVIGNLDLITPTVTMFFLLCYAGVNLSCFLLDLLDAPS 394
                 EP  A L TA +    ++I +LD++ P ++MFFL+CY  VNL+C +  LL  P+
Sbjct: 547 HGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPN 606

Query: 395 WRPRWKFHHWSLSLVGALLC 414
           WRPR+K++HW+LS +G  LC
Sbjct: 607 WRPRFKYYHWALSFLGMSLC 626



 Score =  130 bits (327), Expect = 7e-29
 Identities = 71/180 (39%), Positives = 106/180 (58%), Gaps = 9/180 (5%)

Query: 11  IVGMGGIGGTLLLVALCGTCTFLTAISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGL 70
           +VG  G+   LL+V +C  CT LTAIS+SAIATNG +  GG Y++I R+LGPE G ++GL
Sbjct: 144 MVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGL 203

Query: 71  CFFLGNAVAGALYVLGAVETFLKAV-PAAGIFRETITQVNGTTIAQPIESPSSHDLQIYG 129
           CF+LG   A A+Y+LGA+E  L  + P A IF          + A    + + +++++YG
Sbjct: 204 CFYLGTTFAAAMYILGAIEILLTYIAPPAAIFY--------PSGAHDTSNATLNNMRVYG 255

Query: 130 IVVTIVLCFIVFGGVKMINRVAPAFLIPVLFSLICIYLGILLAREDHPAEGITGLSLETL 189
            +    +  +VF GVK +N+ A  FL  V+ S++ IY G + +  D P   +  L   TL
Sbjct: 256 TIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTL 315


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.326    0.142    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 677,453,582
Number of Sequences: 2790947
Number of extensions: 28715367
Number of successful extensions: 99304
Number of sequences better than 10.0: 799
Number of HSP's better than 10.0 without gapping: 330
Number of HSP's successfully gapped in prelim test: 469
Number of HSP's that attempted gapping in prelim test: 97704
Number of HSP's gapped (non-prelim): 1245
length of query: 414
length of database: 848,049,833
effective HSP length: 130
effective length of query: 284
effective length of database: 485,226,723
effective search space: 137804389332
effective search space used: 137804389332
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 76 (33.9 bits)