BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0028b.3
         (288 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_P52902 Pyruvate dehydrogenase E1 component alpha subun...   492  e-138
UniRef100_P52901 Pyruvate dehydrogenase E1 component alpha subun...   477  e-133
UniRef100_O48685 Pyruvate dehydrogenase E1 alpha subunit [Arabid...   475  e-133
UniRef100_Q8H1Y0 Pyruvate dehydrogenase E1a-like subunit IAR4 [A...   471  e-132
UniRef100_P52903 Pyruvate dehydrogenase E1 component alpha subun...   462  e-129
UniRef100_Q9FR11 Pyruvate dehydrogenase [Lycopersicon esculentum]     459  e-128
UniRef100_Q6Z5N4 Putative pyruvate dehydrogenase E1 alpha subuni...   447  e-124
UniRef100_Q852S0 Pyruvate dehydrogenase E1alpha subunit [Beta vu...   446  e-124
UniRef100_Q9ZQY0 Pyruvate dehydrogenase E1 alpha subunit [Zea mays]   443  e-123
UniRef100_Q852R9 Pyruvate dehydrogenase E1 alpha subunit [Beta v...   442  e-123
UniRef100_Q654V6 Putative pyruvate dehydrogenase E1 alpha subuni...   427  e-118
UniRef100_UPI000026B1A7 UPI000026B1A7 UniRef100 entry                 324  1e-87
UniRef100_Q6DEB0 MGC79036 protein [Xenopus laevis]                    286  4e-76
UniRef100_Q66JA7 MGC80338 protein [Xenopus laevis]                    284  2e-75
UniRef100_UPI0000235263 UPI0000235263 UniRef100 entry                 283  5e-75
UniRef100_UPI00004302DC UPI00004302DC UniRef100 entry                 282  8e-75
UniRef100_UPI00004384ED Pyruvate dehydrogenase [Sus scrofa]           281  1e-74
UniRef100_Q6P948 Zgc:73271 protein [Brachydanio rerio]                281  1e-74
UniRef100_Q10489 Pyruvate dehydrogenase E1 component alpha subun...   281  1e-74
UniRef100_UPI000023D721 UPI000023D721 UniRef100 entry                 280  2e-74

>UniRef100_P52902 Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial
           precursor [Pisum sativum]
          Length = 397

 Score =  492 bits (1267), Expect = e-138
 Identities = 241/289 (83%), Positives = 261/289 (89%), Gaps = 4/289 (1%)

Query: 1   MALSRLASSSSSSSSTVGSKFLKPLTAAFSLRRSISSDSNP-ITIETSVPFTAHNCDPPS 59
           MALSRL+SSSSSS+   GS    P +AAF+L R ISSD+   +TIETS+PFTAHNCDPPS
Sbjct: 1   MALSRLSSSSSSSN---GSNLFNPFSAAFTLNRPISSDTTATLTIETSLPFTAHNCDPPS 57

Query: 60  RSVETSTAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKK 119
           RSV TS +EL SFFR MA MRRMEIAADSLYKA LIRGFCHLYDGQEAVA+GMEAG TKK
Sbjct: 58  RSVTTSPSELLSFFRTMALMRRMEIAADSLYKANLIRGFCHLYDGQEAVAVGMEAGTTKK 117

Query: 120 DAIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGA 179
           D IITAYRDHCTFLGRGGTLL +++ELMGR DGCSKGKGGSMHFY+K++ FYGGHGIVGA
Sbjct: 118 DCIITAYRDHCTFLGRGGTLLRVYAELMGRRDGCSKGKGGSMHFYKKDSGFYGGHGIVGA 177

Query: 180 QVPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGM 239
           QVPLGCG+AF QKY KDE+VTFALYGDGAANQGQLFEALNI+ALWDLPAILVCENNHYGM
Sbjct: 178 QVPLGCGLAFGQKYLKDESVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGM 237

Query: 240 GTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           GTA WR+AKSPAY+KRGDYVPGLKVDGMD LAVKQACKFAKEHALKNGP
Sbjct: 238 GTATWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGP 286


>UniRef100_P52901 Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial
           precursor [Arabidopsis thaliana]
          Length = 389

 Score =  477 bits (1228), Expect = e-133
 Identities = 236/288 (81%), Positives = 258/288 (88%), Gaps = 10/288 (3%)

Query: 1   MALSRLASSSSSSSSTVGSKFLKPLTAAFSLRRSISSDSNPITIETSVPFTAHNCDPPSR 60
           MALSRL+S S+  +        +P +AAFS  R IS+D+ PITIETS+PFTAH CDPPSR
Sbjct: 1   MALSRLSSRSNIIT--------RPFSAAFS--RLISTDTTPITIETSLPFTAHLCDPPSR 50

Query: 61  SVETSTAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKD 120
           SVE+S+ EL  FFR MA MRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEA ITKKD
Sbjct: 51  SVESSSQELLDFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKD 110

Query: 121 AIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQ 180
           AIITAYRDHC FLGRGG+L E+FSELMGR  GCSKGKGGSMHFY+KE++FYGGHGIVGAQ
Sbjct: 111 AIITAYRDHCIFLGRGGSLHEVFSELMGRQAGCSKGKGGSMHFYKKESSFYGGHGIVGAQ 170

Query: 181 VPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMG 240
           VPLGCG+AFAQKY+K+EAVTFALYGDGAANQGQLFEALNI+ALWDLPAILVCENNHYGMG
Sbjct: 171 VPLGCGIAFAQKYNKEEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMG 230

Query: 241 TAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           TAEWRAAKSP+YYKRGDYVPGLKVDGMD  AVKQACKFAK+HAL+ GP
Sbjct: 231 TAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKQHALEKGP 278


>UniRef100_O48685 Pyruvate dehydrogenase E1 alpha subunit [Arabidopsis thaliana]
          Length = 393

 Score =  475 bits (1223), Expect = e-133
 Identities = 231/290 (79%), Positives = 259/290 (88%), Gaps = 10/290 (3%)

Query: 1   MALSRLASSSSSSSSTVGSKFLKPLTAAF--SLRRSISSDSNPITIETSVPFTAHNCDPP 58
           MALSRL+S S++        FLKP   A   S+RR +S+DS+PITIET+VPFT+H C+ P
Sbjct: 1   MALSRLSSRSNT--------FLKPAITALPSSIRRHVSTDSSPITIETAVPFTSHLCESP 52

Query: 59  SRSVETSTAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITK 118
           SRSVETS+ E+ +FFR MA MRRMEIAADSLYKAKLIRGFCHLYDGQEA+A+GMEA ITK
Sbjct: 53  SRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEALAVGMEAAITK 112

Query: 119 KDAIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVG 178
           KDAIIT+YRDHCTF+GRGG L++ FSELMGR  GCS GKGGSMHFY+K+ +FYGGHGIVG
Sbjct: 113 KDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVG 172

Query: 179 AQVPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYG 238
           AQ+PLGCG+AFAQKY+KDEAVTFALYGDGAANQGQLFEALNI+ALWDLPAILVCENNHYG
Sbjct: 173 AQIPLGCGLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYG 232

Query: 239 MGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           MGTA WR+AKSPAY+KRGDYVPGLKVDGMD LAVKQACKFAKEHALKNGP
Sbjct: 233 MGTATWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGP 282


>UniRef100_Q8H1Y0 Pyruvate dehydrogenase E1a-like subunit IAR4 [Arabidopsis thaliana]
          Length = 393

 Score =  471 bits (1213), Expect = e-132
 Identities = 230/290 (79%), Positives = 258/290 (88%), Gaps = 10/290 (3%)

Query: 1   MALSRLASSSSSSSSTVGSKFLKPLTAAF--SLRRSISSDSNPITIETSVPFTAHNCDPP 58
           MALSRL+S S++        FLKP   A   S+RR +S+DS+PITIET+VPFT+H C+ P
Sbjct: 1   MALSRLSSRSNT--------FLKPAITALPSSIRRHVSTDSSPITIETAVPFTSHLCESP 52

Query: 59  SRSVETSTAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITK 118
           SRSVETS+ E+ +FFR MA MRRMEIAADSLYKAKLIRGFCHLYDGQEA+A+GMEA ITK
Sbjct: 53  SRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEALAVGMEAAITK 112

Query: 119 KDAIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVG 178
           KDAIIT+YRDHCTF+GRGG L++ FSELMGR  GCS GKGGSMHFY+K+ +FYGGHGIVG
Sbjct: 113 KDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVG 172

Query: 179 AQVPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYG 238
           AQ+PLGCG+AFAQKY+KDEAVTFALYGDGAANQGQLFEALNI+ALWDLPAILVCENNH G
Sbjct: 173 AQIPLGCGLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHDG 232

Query: 239 MGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           MGTA WR+AKSPAY+KRGDYVPGLKVDGMD LAVKQACKFAKEHALKNGP
Sbjct: 233 MGTATWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGP 282


>UniRef100_P52903 Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial
           precursor [Solanum tuberosum]
          Length = 391

 Score =  462 bits (1188), Expect = e-129
 Identities = 223/277 (80%), Positives = 246/277 (88%), Gaps = 1/277 (0%)

Query: 13  SSSTVGSKFLKPLTAAFSLRRSISSDSNP-ITIETSVPFTAHNCDPPSRSVETSTAELHS 71
           S+S   +  +KPL+AA    R +SSDS   IT+ETS+PFT+HN DPPSRSVETS  EL +
Sbjct: 4   STSRAINHIMKPLSAAVCATRRLSSDSTATITVETSLPFTSHNIDPPSRSVETSPKELMT 63

Query: 72  FFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCT 131
           FF+ M  MRRMEIAADSLYKAKLIRGFCHLYDGQEAVA+GMEA ITKKD IITAYRDHC 
Sbjct: 64  FFKDMTEMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAVGMEAAITKKDCIITAYRDHCI 123

Query: 132 FLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQ 191
           FLGRGGTL+E F+ELMGR DGCS+GKGGSMHFY+KE+ FYGGHGIVGAQVPLG G+AFAQ
Sbjct: 124 FLGRGGTLVEAFAELMGRRDGCSRGKGGSMHFYKKESGFYGGHGIVGAQVPLGIGLAFAQ 183

Query: 192 KYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPA 251
           KY K++ VTFA+YGDGAANQGQLFEALN+AALWDLPAILVCENNHYGMGTAEWRAAKSPA
Sbjct: 184 KYKKEDYVTFAMYGDGAANQGQLFEALNMAALWDLPAILVCENNHYGMGTAEWRAAKSPA 243

Query: 252 YYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           YYKRGDYVPGL+VDGMDV AVKQAC FAK+HALKNGP
Sbjct: 244 YYKRGDYVPGLRVDGMDVFAVKQACTFAKQHALKNGP 280


>UniRef100_Q9FR11 Pyruvate dehydrogenase [Lycopersicon esculentum]
          Length = 391

 Score =  459 bits (1182), Expect = e-128
 Identities = 222/277 (80%), Positives = 245/277 (88%), Gaps = 1/277 (0%)

Query: 13  SSSTVGSKFLKPLTAAFSLRRSISSDSNP-ITIETSVPFTAHNCDPPSRSVETSTAELHS 71
           S+S   +  +KPL+ A    R +SSDS   IT+ETS+PFT+HN DPPSRSVETS  EL +
Sbjct: 4   STSRAINHIMKPLSRAVCATRRLSSDSTATITVETSLPFTSHNVDPPSRSVETSPMELMT 63

Query: 72  FFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCT 131
           FF+ M  MRRMEIAADSLYKAKLIRGFCHLYDGQEAVA+GMEA ITKKD IITAYRDHC 
Sbjct: 64  FFKDMTEMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAVGMEAAITKKDCIITAYRDHCI 123

Query: 132 FLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQ 191
           FLGRGGTL+E F+ELMGR DGCS+GKGGSMHFY+KE+ FYGGHGIVGAQVPLG G+AFAQ
Sbjct: 124 FLGRGGTLVESFAELMGRRDGCSRGKGGSMHFYKKESGFYGGHGIVGAQVPLGIGLAFAQ 183

Query: 192 KYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPA 251
           KY K++ VTFA+YGDGAANQGQLFEALN+AALWDLPAILVCENNHYGMGTAEWRAAKSPA
Sbjct: 184 KYKKEDYVTFAMYGDGAANQGQLFEALNMAALWDLPAILVCENNHYGMGTAEWRAAKSPA 243

Query: 252 YYKRGDYVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           YYKRGDYVPGL+VDGMDV AVKQAC FAK+HALKNGP
Sbjct: 244 YYKRGDYVPGLRVDGMDVFAVKQACAFAKQHALKNGP 280


>UniRef100_Q6Z5N4 Putative pyruvate dehydrogenase E1 alpha subunit [Oryza sativa]
          Length = 390

 Score =  447 bits (1149), Expect = e-124
 Identities = 212/256 (82%), Positives = 231/256 (89%)

Query: 33  RSISSDSNPITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMATMRRMEIAADSLYKA 92
           RSIS  + P+TIETSVPFT+H  DPPSR V T+ AEL +FFR M+ MRRMEIAADSLYKA
Sbjct: 24  RSISDSTAPLTIETSVPFTSHIVDPPSRDVTTTPAELLTFFRDMSVMRRMEIAADSLYKA 83

Query: 93  KLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIFSELMGRVDG 152
           KLIRGFCHLYDGQEAVA+GMEA IT+ D+IITAYRDHCT+L RGG L+  F+ELMGR  G
Sbjct: 84  KLIRGFCHLYDGQEAVAVGMEAAITRSDSIITAYRDHCTYLARGGDLVSAFAELMGRQAG 143

Query: 153 CSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFALYGDGAANQG 212
           CS+GKGGSMHFY+K+ NFYGGHGIVGAQVPLGCG+AFAQKY K+E  TFALYGDGAANQG
Sbjct: 144 CSRGKGGSMHFYKKDANFYGGHGIVGAQVPLGCGLAFAQKYRKEETATFALYGDGAANQG 203

Query: 213 QLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAV 272
           QLFEALNI+ALW LPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAV
Sbjct: 204 QLFEALNISALWKLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAV 263

Query: 273 KQACKFAKEHALKNGP 288
           KQACKFAKEHA+ NGP
Sbjct: 264 KQACKFAKEHAIANGP 279


>UniRef100_Q852S0 Pyruvate dehydrogenase E1alpha subunit [Beta vulgaris]
          Length = 395

 Score =  446 bits (1147), Expect = e-124
 Identities = 215/271 (79%), Positives = 242/271 (88%), Gaps = 1/271 (0%)

Query: 19  SKFLKPLTAAFSLRRSISSDSNP-ITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMA 77
           S  L PLT+  +  R +SSDS   +TIETSVPF +H  +PPSRSV+T+ AEL ++FR MA
Sbjct: 14  SSVLLPLTSTHTHSRRLSSDSTKTLTIETSVPFKSHIVEPPSRSVDTTPAELMTYFRDMA 73

Query: 78  TMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGG 137
            MRRMEIA+DSLYKAKLIRGFCHLYDGQEAVA+GMEA ITKKD IITAYRDHC +L RGG
Sbjct: 74  LMRRMEIASDSLYKAKLIRGFCHLYDGQEAVAVGMEAAITKKDNIITAYRDHCIYLARGG 133

Query: 138 TLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDE 197
           +LL  F+ELMGR DGCS+GKGGSMHFY+K++ FYGGHGIVGAQVPLG G+AFAQKY+K++
Sbjct: 134 SLLSAFAELMGRQDGCSRGKGGSMHFYKKDSGFYGGHGIVGAQVPLGVGLAFAQKYNKED 193

Query: 198 AVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGD 257
            V+FALYGDGAANQGQLFEALN+AALWDLPAILVCENNHYGMGTAEWRAAKSP+YYKRGD
Sbjct: 194 CVSFALYGDGAANQGQLFEALNMAALWDLPAILVCENNHYGMGTAEWRAAKSPSYYKRGD 253

Query: 258 YVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           YVPGLKVDGMDVLAVKQACKFAKE+ LKNGP
Sbjct: 254 YVPGLKVDGMDVLAVKQACKFAKEYVLKNGP 284


>UniRef100_Q9ZQY0 Pyruvate dehydrogenase E1 alpha subunit [Zea mays]
          Length = 392

 Score =  443 bits (1139), Expect = e-123
 Identities = 211/261 (80%), Positives = 231/261 (87%)

Query: 28  AFSLRRSISSDSNPITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMATMRRMEIAAD 87
           AF   R IS  +  +TIETSVPFT+H  DPPSR V T+ AEL +FFR M+ MRRMEIAAD
Sbjct: 21  AFMAARPISDSTAALTIETSVPFTSHLVDPPSRDVTTTPAELVTFFRDMSLMRRMEIAAD 80

Query: 88  SLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIFSELM 147
           SLYKAKLIRGFCHLYDGQEAVA+GMEA IT+ D+IITAYRDHCT+L RGG L+  FSELM
Sbjct: 81  SLYKAKLIRGFCHLYDGQEAVAVGMEAAITRSDSIITAYRDHCTYLARGGDLVSAFSELM 140

Query: 148 GRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFALYGDG 207
           GR  GCS+GKGGSMHFY+K+ NFYGGHGIVGAQVPLGCG+AFAQKY K++  TFALYGDG
Sbjct: 141 GREAGCSRGKGGSMHFYKKDANFYGGHGIVGAQVPLGCGLAFAQKYKKEDTATFALYGDG 200

Query: 208 AANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGM 267
           AANQGQLFEALNI+ALW LPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGM
Sbjct: 201 AANQGQLFEALNISALWKLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGM 260

Query: 268 DVLAVKQACKFAKEHALKNGP 288
           DVLAVKQACKFAK+HA+ NGP
Sbjct: 261 DVLAVKQACKFAKDHAVANGP 281


>UniRef100_Q852R9 Pyruvate dehydrogenase E1 alpha subunit [Beta vulgaris]
          Length = 395

 Score =  442 bits (1136), Expect = e-123
 Identities = 213/271 (78%), Positives = 241/271 (88%), Gaps = 1/271 (0%)

Query: 19  SKFLKPLTAAFSLRRSISSDSNP-ITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMA 77
           S  L PLT+  +  R +SSDS   +TIETSVPF +H  +PPSRSV+T+ AEL ++FR MA
Sbjct: 14  SSLLLPLTSTHTHSRRLSSDSTKTLTIETSVPFKSHIVEPPSRSVDTTPAELMTYFRDMA 73

Query: 78  TMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGG 137
            MRRMEIA+DSLYKAKLIRGFCHLYDGQEAVA+GMEA ITKKD IITAYRDHC +L RGG
Sbjct: 74  LMRRMEIASDSLYKAKLIRGFCHLYDGQEAVAVGMEAAITKKDNIITAYRDHCIYLARGG 133

Query: 138 TLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDE 197
           +LL  F+EL+GR DGCS+GKGGSMHFY+K++ FYGGHGIVGAQVPLG G+AFAQKY+K++
Sbjct: 134 SLLSAFAELVGRQDGCSRGKGGSMHFYKKDSGFYGGHGIVGAQVPLGVGLAFAQKYNKED 193

Query: 198 AVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGD 257
            V+FALYGDGAANQGQLFEALN+AALWDLPAILVCENNHYGMGTAEWRAAKSP+YYKRGD
Sbjct: 194 CVSFALYGDGAANQGQLFEALNMAALWDLPAILVCENNHYGMGTAEWRAAKSPSYYKRGD 253

Query: 258 YVPGLKVDGMDVLAVKQACKFAKEHALKNGP 288
           YVPGLKVDGMDVLAVKQACK AKE+ LKNGP
Sbjct: 254 YVPGLKVDGMDVLAVKQACKSAKEYVLKNGP 284


>UniRef100_Q654V6 Putative pyruvate dehydrogenase E1 alpha subunit [Oryza sativa]
          Length = 398

 Score =  427 bits (1097), Expect = e-118
 Identities = 202/265 (76%), Positives = 227/265 (85%), Gaps = 3/265 (1%)

Query: 24  PLTAAFSLRRSISSDSNPITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMATMRRME 83
           PLT +    R +S  + P+TIETSVP+ +H  DPP R V T+  EL +FFR M+ MRR E
Sbjct: 26  PLTTSV---RGVSDSTEPLTIETSVPYKSHIVDPPPREVATTARELATFFRDMSAMRRAE 82

Query: 84  IAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIF 143
           IAADSLYKAKLIRGFCHLYDGQEAVA+GMEA  T+ DAIITAYRDHC +L RGG L  +F
Sbjct: 83  IAADSLYKAKLIRGFCHLYDGQEAVAVGMEAATTRADAIITAYRDHCAYLARGGDLAALF 142

Query: 144 SELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFAL 203
           +ELMGR  GCS+GKGGSMH Y+K+ NFYGGHGIVGAQVPLGCG+AFAQ+Y K+ AVTF L
Sbjct: 143 AELMGRRGGCSRGKGGSMHLYKKDANFYGGHGIVGAQVPLGCGLAFAQRYRKEAAVTFDL 202

Query: 204 YGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLK 263
           YGDGAANQGQLFEALN+AALW LP +LVCENNHYGMGTAEWRA+KSPAYYKRGDYVPGLK
Sbjct: 203 YGDGAANQGQLFEALNMAALWKLPVVLVCENNHYGMGTAEWRASKSPAYYKRGDYVPGLK 262

Query: 264 VDGMDVLAVKQACKFAKEHALKNGP 288
           VDGMDVLAVKQACKFAK+HAL+NGP
Sbjct: 263 VDGMDVLAVKQACKFAKQHALENGP 287


>UniRef100_UPI000026B1A7 UPI000026B1A7 UniRef100 entry
          Length = 227

 Score =  324 bits (831), Expect = 1e-87
 Identities = 153/211 (72%), Positives = 175/211 (82%), Gaps = 1/211 (0%)

Query: 79  MRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGT 138
           MRR+EIAAD LYK K IRGFCHLYDGQEAV +GME  +TK DA++T+YRDHC  LGRGGT
Sbjct: 1   MRRLEIAADVLYKGKFIRGFCHLYDGQEAVVVGMETVLTKDDAVVTSYRDHCVHLGRGGT 60

Query: 139 LLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEA 198
            LE+ +ELMGRVDG +KG GGSMH YR+E NF+GG+GIVGAQ  +G G+ FA KY+K   
Sbjct: 61  PLEVMAELMGRVDGAAKGIGGSMHMYRREANFFGGNGIVGAQTAIGAGLGFAFKYNKQPN 120

Query: 199 VTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDY 258
           V   +YGDGAANQGQLFEALN+AALWDLP I +CENNHYGMGTA+ R+AKSP YYKRGDY
Sbjct: 121 VAVTMYGDGAANQGQLFEALNMAALWDLPVIFMCENNHYGMGTAQERSAKSPVYYKRGDY 180

Query: 259 VPGLKVDGMDVLAVKQACKFAKEHALK-NGP 288
           VPGLKVDGMD LAVKQA KFAKE+ +   GP
Sbjct: 181 VPGLKVDGMDALAVKQAMKFAKEYCVSGKGP 211


>UniRef100_Q6DEB0 MGC79036 protein [Xenopus laevis]
          Length = 400

 Score =  286 bits (732), Expect = 4e-76
 Identities = 150/277 (54%), Positives = 186/277 (66%), Gaps = 11/277 (3%)

Query: 14  SSTVGSKFLKPLT-AAFSLRRSISSDSNPITIETSVPFTAHNCD-------PPSRSVETS 65
           S  +  K  KP+T AA    R + +  N     +   F    CD       PP+++V T 
Sbjct: 9   SRVLKGKAQKPVTGAANEAVRVMVASRNYADFASEATFDVKKCDVHRLEEGPPTQAVLTR 68

Query: 66  TAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITA 125
              L  ++R M T+RRME+ +D LYK K+IRGFCHLYDGQEA  +G+E+GI   D +ITA
Sbjct: 69  EQGLQ-YYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLESGINPTDHLITA 127

Query: 126 YRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGC 185
           YR H     RG ++ EI +EL GR  GC+KGKGGSMH Y K  NFYGG+GIVGAQVPLG 
Sbjct: 128 YRAHGYTYTRGVSVKEILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPLGA 185

Query: 186 GVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWR 245
           GVA A K+   + +  +LYGDGAANQGQ+FE  N+AALW LP I +CENN YGMGT+  R
Sbjct: 186 GVALACKFFGKDEICVSLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMGTSVER 245

Query: 246 AAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAKEH 282
           AA S  YYKRGDY+PGL+VDGMDVL V++A KFA +H
Sbjct: 246 AAASTDYYKRGDYIPGLRVDGMDVLCVREATKFAADH 282


>UniRef100_Q66JA7 MGC80338 protein [Xenopus laevis]
          Length = 400

 Score =  284 bits (726), Expect = 2e-75
 Identities = 148/268 (55%), Positives = 182/268 (67%), Gaps = 11/268 (4%)

Query: 23  KPLT-AAFSLRRSISSDSNPITIETSVPFTAHNCD-------PPSRSVETSTAELHSFFR 74
           KP+T AA    R + +  N     +   F    CD       PP+++V T    L  ++R
Sbjct: 18  KPVTGAANEAVRVMMASRNYADFASEATFDIKKCDIHRLEEEPPTQAVLTREEGLQ-YYR 76

Query: 75  QMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLG 134
            M T+RRME+ +D LYK K+IRGFCHLYDGQEA  +G+E+GI   D +ITAYR H     
Sbjct: 77  TMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLESGINPTDHLITAYRAHGYTYT 136

Query: 135 RGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYS 194
           RG ++ EI +EL GR  GC+KGKGGSMH Y K  NFYGG+GIVGAQVPLG GVA A K+ 
Sbjct: 137 RGVSVKEILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPLGAGVALACKFF 194

Query: 195 KDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYK 254
               +  +LYGDGAANQGQ+FE  N+AALW LP I +CENN YGMGT+  RAA S  YYK
Sbjct: 195 GKNEICVSLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYK 254

Query: 255 RGDYVPGLKVDGMDVLAVKQACKFAKEH 282
           RGDY+PGL+VDGMDVL V++A KFA +H
Sbjct: 255 RGDYIPGLRVDGMDVLCVREATKFAADH 282


>UniRef100_UPI0000235263 UPI0000235263 UniRef100 entry
          Length = 405

 Score =  283 bits (723), Expect = 5e-75
 Identities = 143/265 (53%), Positives = 187/265 (69%), Gaps = 5/265 (1%)

Query: 27  AAFSLRRSISSDSN-PITIETS-VPFTAHNCDPPSRSVETSTAELHSFFRQMATMRRMEI 84
           AA S   +I  D N P T+  S   F  +  DPP  ++E +  EL   +  M  MRRME+
Sbjct: 31  AASSHAENIPEDENKPFTVRLSDESFETYEIDPPPYTLEVTKKELKQMYYDMVAMRRMEM 90

Query: 85  AADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIFS 144
           AAD LYK K IRGFCHL  GQEAVA+G+E  +T++D IITAYR H   + RGGT+  I  
Sbjct: 91  AADRLYKEKKIRGFCHLSTGQEAVAVGIEHALTREDKIITAYRCHGYAMMRGGTIRSIIG 150

Query: 145 ELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFALY 204
           EL+GR +G + GKGGSMH +    NFYGG+GIVGAQVP+G G+AFAQ+Y+++++ +  LY
Sbjct: 151 ELLGRREGIAYGKGGSMHMFAP--NFYGGNGIVGAQVPVGAGLAFAQQYNEEKSTSVVLY 208

Query: 205 GDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKV 264
           GDGA+NQGQ+FEA N+A LW+LP +  CENN YGMGT+  R++    YYKRG Y+PG+KV
Sbjct: 209 GDGASNQGQVFEAFNMAKLWNLPVLFGCENNKYGMGTSAARSSALTDYYKRGQYIPGIKV 268

Query: 265 DGMDVLAVKQACKFAKEHALK-NGP 288
           +GMDVLA K A K+ K++A+  NGP
Sbjct: 269 NGMDVLATKAAVKYGKDYAISGNGP 293


>UniRef100_UPI00004302DC UPI00004302DC UniRef100 entry
          Length = 413

 Score =  282 bits (721), Expect = 8e-75
 Identities = 139/249 (55%), Positives = 183/249 (72%), Gaps = 3/249 (1%)

Query: 36  SSDSNPITIETSVP-FTAHNCDPPSRSVETSTAELHSFFRQMATMRRMEIAADSLYKAKL 94
           +S S P  ++     F ++ CD P      +  EL + +R M  MRRME AAD+LYK KL
Sbjct: 47  ASGSEPFKVQLHADSFHSYRCDAPPPETTVTKDELINMYRTMVQMRRMEQAADALYKQKL 106

Query: 95  IRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCS 154
           IRGFCHL  GQEAV++GME  IT +D +IT+YR H   + RGGT+  + +ELMGR DG S
Sbjct: 107 IRGFCHLAIGQEAVSVGMETAITGQDRVITSYRCHTFAVLRGGTIKGVIAELMGRKDGMS 166

Query: 155 KGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQL 214
            GKGGSMH +    +F+GG+GIVGAQVP+G GVA AQKY+K++A TFALYGDGAANQGQ+
Sbjct: 167 FGKGGSMHIFTP--SFFGGNGIVGAQVPVGAGVALAQKYNKEKAATFALYGDGAANQGQV 224

Query: 215 FEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQ 274
           FEA N+A LW+LP + VCENN YGMGT+  R++ +  ++ RGD +PGL+V+GMD+LAV++
Sbjct: 225 FEAFNMAKLWNLPCVFVCENNKYGMGTSAERSSMNTQFFTRGDQIPGLQVNGMDILAVRE 284

Query: 275 ACKFAKEHA 283
           A K+A+E A
Sbjct: 285 ATKWAREWA 293


>UniRef100_UPI00004384ED Pyruvate dehydrogenase [Sus scrofa]
          Length = 564

 Score =  281 bits (720), Expect = 1e-74
 Identities = 138/211 (65%), Positives = 161/211 (75%), Gaps = 2/211 (0%)

Query: 72  FFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCT 131
           ++R M TMRRME+ AD LYK K+IRGFCHLYDGQEA A+G+EAGI   D +ITAYR H  
Sbjct: 252 YYRTMQTMRRMELKADQLYKQKIIRGFCHLYDGQEACAVGIEAGINLSDHLITAYRAHGY 311

Query: 132 FLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQ 191
            L RGGT+ EI +EL GR  G +KGKGGSMH Y K  +FYGG+GIVGAQVPLG GVA A 
Sbjct: 312 TLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--HFYGGNGIVGAQVPLGAGVALAC 369

Query: 192 KYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPA 251
           KY     +   LYGDGAANQGQ+FE  N+A+LW LP I +CENN YGMGT+  RAA S  
Sbjct: 370 KYQGKNELCVCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTD 429

Query: 252 YYKRGDYVPGLKVDGMDVLAVKQACKFAKEH 282
           YYKRGD++PGL+VDGMDVL V++A KFA EH
Sbjct: 430 YYKRGDFIPGLRVDGMDVLCVREATKFAAEH 460


>UniRef100_Q6P948 Zgc:73271 protein [Brachydanio rerio]
          Length = 393

 Score =  281 bits (720), Expect = 1e-74
 Identities = 138/211 (65%), Positives = 161/211 (75%), Gaps = 2/211 (0%)

Query: 72  FFRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCT 131
           ++R M TMRRME+ AD LYK K+IRGFCHLYDGQEA A+G+EAGI   D +ITAYR H  
Sbjct: 67  YYRTMQTMRRMELKADQLYKQKIIRGFCHLYDGQEACAVGIEAGINLSDHLITAYRAHGY 126

Query: 132 FLGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQ 191
            L RGGT+ EI +EL GR  G +KGKGGSMH Y K  +FYGG+GIVGAQVPLG GVA A 
Sbjct: 127 TLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--HFYGGNGIVGAQVPLGAGVALAC 184

Query: 192 KYSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPA 251
           KY     +   LYGDGAANQGQ+FE  N+A+LW LP I +CENN YGMGT+  RAA S  
Sbjct: 185 KYQGKNELCVCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTD 244

Query: 252 YYKRGDYVPGLKVDGMDVLAVKQACKFAKEH 282
           YYKRGD++PGL+VDGMDVL V++A KFA EH
Sbjct: 245 YYKRGDFIPGLRVDGMDVLCVREATKFAAEH 275


>UniRef100_Q10489 Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial
           precursor [Schizosaccharomyces pombe]
          Length = 409

 Score =  281 bits (719), Expect = 1e-74
 Identities = 141/246 (57%), Positives = 175/246 (70%), Gaps = 3/246 (1%)

Query: 41  PITIETSVPFTAHNCDPPSRSVETSTAELHSFFRQMATMRRMEIAADSLYKAKLIRGFCH 100
           P+ ++ SV F  +  D PS  +E +  EL   + +M T+RR+E+A D+LYKAK IRGFCH
Sbjct: 51  PVKLDDSV-FEGYKIDVPSTEIEVTKGELLGLYEKMVTIRRLELACDALYKAKKIRGFCH 109

Query: 101 LYDGQEAVAIGMEAGITKKDAIITAYRDHCTFLGRGGTLLEIFSELMGRVDGCSKGKGGS 160
           L  GQEAVA G+E  IT  D+IIT+YR H     RG ++  I  ELMGR  G SKGKGGS
Sbjct: 110 LSIGQEAVAAGIEGAITLDDSIITSYRCHGFAYTRGLSIRSIIGELMGRQCGASKGKGGS 169

Query: 161 MHFYRKETNFYGGHGIVGAQVPLGCGVAFAQKYSKDEAVTFALYGDGAANQGQLFEALNI 220
           MH + K  NFYGG+GIVGAQ+PLG G+ FAQKY +    TFALYGDGA+NQGQ FEA N+
Sbjct: 170 MHIFAK--NFYGGNGIVGAQIPLGAGIGFAQKYLEKPTTTFALYGDGASNQGQAFEAFNM 227

Query: 221 AALWDLPAILVCENNHYGMGTAEWRAAKSPAYYKRGDYVPGLKVDGMDVLAVKQACKFAK 280
           A LW LP I  CENN YGMGT+  R++    +YKRG Y+PGL V+GMDVLAV QA KFAK
Sbjct: 228 AKLWGLPVIFACENNKYGMGTSAERSSAMTEFYKRGQYIPGLLVNGMDVLAVLQASKFAK 287

Query: 281 EHALKN 286
           ++ ++N
Sbjct: 288 KYTVEN 293


>UniRef100_UPI000023D721 UPI000023D721 UniRef100 entry
          Length = 409

 Score =  280 bits (717), Expect = 2e-74
 Identities = 146/277 (52%), Positives = 188/277 (67%), Gaps = 18/277 (6%)

Query: 28  AFSLRRSISSDSNPITIETSVP---------------FTAHNCDPPSRSVETSTAELHSF 72
           A++  RS+++D+   ++  SVP               F  +  DPP  ++E +  EL   
Sbjct: 22  AYTAVRSVTTDAASASLSHSVPKADDEPFSVNLSDESFETYELDPPPYTLEVTKKELKDM 81

Query: 73  FRQMATMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAGITKKDAIITAYRDHCTF 132
           +R+M   R+ME+AAD LYK K IRGFCHL  GQEAVA+G+E  ITK+D IITAYR H   
Sbjct: 82  YREMVVTRQMEMAADRLYKEKKIRGFCHLSTGQEAVAVGIEHAITKEDDIITAYRCHGYA 141

Query: 133 LGRGGTLLEIFSELMGRVDGCSKGKGGSMHFYRKETNFYGGHGIVGAQVPLGCGVAFAQK 192
           L RG ++  I  EL+GR +G S GKGGSMH + K   FYGG+GIVGAQVP+G G+AFA K
Sbjct: 142 LLRGASVRSIIGELLGRREGISYGKGGSMHMFAK--GFYGGNGIVGAQVPVGAGLAFAHK 199

Query: 193 YSKDEAVTFALYGDGAANQGQLFEALNIAALWDLPAILVCENNHYGMGTAEWRAAKSPAY 252
           Y+ ++  +  LYGDGA+NQGQ+FEA N+A LW+LPA+  CENN YGMGTA  R++    Y
Sbjct: 200 YNNNKNASIILYGDGASNQGQVFEAFNMAKLWNLPALFGCENNKYGMGTAAARSSALTDY 259

Query: 253 YKRGDYVPGLKVDGMDVLAVKQACKFAKEH-ALKNGP 288
           YKRG Y+PGLKV+GMDVLAVK A K+ KE+ A   GP
Sbjct: 260 YKRGQYIPGLKVNGMDVLAVKAAVKYGKEYTAADKGP 296


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.319    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 468,378,754
Number of Sequences: 2790947
Number of extensions: 19606715
Number of successful extensions: 50694
Number of sequences better than 10.0: 1149
Number of HSP's better than 10.0 without gapping: 909
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 49072
Number of HSP's gapped (non-prelim): 1245
length of query: 288
length of database: 848,049,833
effective HSP length: 126
effective length of query: 162
effective length of database: 496,390,511
effective search space: 80415262782
effective search space used: 80415262782
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 74 (33.1 bits)