BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0587.6
         (1079 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

XPO1_DROME (Q9TVM2) Exportin 1 (Chromosome region maintenance 1 ...   983  0.0
XPO1_SCHPO (P14068) Exportin 1 (Chromosome region maintenance pr...   978  0.0
XPO1_YEAST (P30822) Exportin 1 (Chromosome region maintenance pr...   856  0.0
YNR7_SCHPO (Q9USZ2) Hypothetical protein C11G11.07 in chromosome II    60  3e-08
TNP1_MOUSE (Q8BFY9) Transportin 1 (Importin beta-2) (Karyopherin...    60  3e-08
TNP1_HUMAN (Q92973) Transportin 1 (Importin beta-)2 (Karyopherin...    60  3e-08
TNP2_HUMAN (O14787) Transportin 2 (Karyopherin beta-2b)                57  3e-07
TNP2_MOUSE (Q99LG2) Transportin 2 (Karyopherin beta-2b)                57  3e-07
XPOT_HUMAN (O43592) Exportin T (tRNA exportin) (Exportin(tRNA))        52  1e-05
XPO7_MOUSE (Q9EPK7) Exportin 7 (Ran-binding protein 16)                38  0.13
XPO7_HUMAN (Q9UIA9) Exportin 7 (Ran-binding protein 16)                38  0.13
YKX1_SCHPO (O14116) Hypothetical protein C328.01c in chromosome I      38  0.17
LOS1_YEAST (P33418) LOS1 protein                                       36  0.49
IMB2_SCHPO (O14089) Putative importin beta-2 subunit (Karyopheri...    35  0.83
YAA2_SCHPO (Q09796) Hypothetical protein C22G7.02 in chromosome I      34  1.9
TPO3_MOUSE (Q6P2B1) Transportin 3                                      34  1.9
TPO3_HUMAN (Q9Y5L0) Transportin 3 (Transportin-SR) (TRN-SR) (Imp...    34  1.9
CSE1_SCHPO (O13671) Importin-alpha re-exporter (Cellular apoptos...    34  2.4
CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7...    34  2.4
RYR1_PIG (P16960) Ryanodine receptor 1 (Skeletal muscle-type rya...    33  4.1

>XPO1_DROME (Q9TVM2) Exportin 1 (Chromosome region maintenance 1
            protein) (Embargoed protein)
          Length = 1063

 Score =  983 bits (2541), Expect = 0.0
 Identities = 508/1083 (46%), Positives = 704/1083 (64%), Gaps = 37/1083 (3%)

Query: 3    AEKLRDLSQPIDVPLLDATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQ 62
            A KL D SQ +D+ LLD  V   Y T   EQ   A  IL  L+ +P+ W +V  IL+ +Q
Sbjct: 10   AGKLLDFSQKLDINLLDKIVEVVY-TAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYSQ 68

Query: 63   NLNTKFFALQVLEGVIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLN 122
            N  TKF+ALQ+LE VIK RW  LP  Q +G+K ++  +I++ S +       ++Y+NKLN
Sbjct: 69   NQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLN 128

Query: 123  IILVQILKHEWPLRWRSFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKI 182
            +ILV ILK EWP  W +FI D+V A+KT+E++C N M ILK LSEEVFDFS+G++TQ K 
Sbjct: 129  MILVHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKA 188

Query: 183  KELKQSLNSEFQLIHELCLYVLSASQRAELIRATLSTLHAFLSWIPLGYIFESPLLETLL 242
            K LK ++ SEF  I  LC +VL  S  A LI  TL TL  FL+WIPLGYIFE+  +ETL+
Sbjct: 189  KHLKDTMCSEFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLI 248

Query: 243  -KFFPLPVYRNLTLKCLIEVAALQFGDYYDTQYTKMYNIFMVQLQTILLPTTNIPEAYAQ 301
             KF  +P++RN+TLKCL E+A L   +Y D  +  ++   MVQL+ I+    N+   +  
Sbjct: 249  FKFLSVPMFRNVTLKCLSEIAGLTAANY-DENFATLFKDTMVQLEQIVGQNMNMNHVFKH 307

Query: 302  GSSEEQTFIQNLALFFTSFYKVHIRILESTQENIAALLSGLEYLINISYVDDTEVFKVCL 361
            GS  EQ  + NLA+F  +F K H +++E  +  +  L   L YL+ IS V+D EVFK+CL
Sbjct: 308  GSDTEQELVLNLAMFLCTFLKEHGKLVEDAKY-VDYLNQALMYLVMISEVEDVEVFKICL 366

Query: 362  DYWNILVSELFEPHRSLENPAAAATNMLGNQQAPLMPPGMVDGLGSQLLQRRQLYAGPMS 421
            +YWN LV +L+                     +    P +      Q+  RR+ YA  +S
Sbjct: 367  EYWNSLVEDLYN--------------------SEFFHPTLESTKRQQVYPRRRFYAPILS 406

Query: 422  KLRTLMICRMAKPEEVLIIEDENGNIVRETLKDNDVLVQYKIMRETLIYLSHLDHDDTER 481
            K+R +MI RMAKPEEVL++E+ENG +VRE +KD + +  YK MRETL++L+HLD  DT+R
Sbjct: 407  KVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKNMRETLVFLTHLDSVDTDR 466

Query: 482  QMLRKLSKQLGGEDWTWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGK 541
             M  KL  Q+ G +++W NLNTLCWAIGSISG+  E+ E RFLV VI+DLL LCE  KGK
Sbjct: 467  IMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLLGLCEQKKGK 526

Query: 542  DNKAVIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQK 601
            DNKA+IASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHE+H GVQDMACDTF+KI  K
Sbjct: 527  DNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAIK 586

Query: 602  CKRKFVITQLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYL 661
            C+R FV  Q  E   F+ E+L+ +S+ I DL+P Q+HTFYE+VG M+ A+ D  ++D  +
Sbjct: 587  CRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLI 646

Query: 662  QRLMHLPNQKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFLPQISLIF 721
            +R M LPNQ W +II +A +NVDFLK+   ++ + +IL+TN +   +LG  ++ Q+  I+
Sbjct: 647  ERYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIY 706

Query: 722  LDMLNVYRMYSELISKSIAEGGPYASRTSFVKLLRSVKRETLKLIETFLDKAEDQPQIGK 781
            LDMLNVY++ SE I ++I   G   +    +K +  VK+ETL LI  ++ ++ D   +  
Sbjct: 707  LDMLNVYKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMD 766

Query: 782  QFVPPMMDPVLGDYAR-NVPDARESEVLSLFATIVNKYKAAMVEDVPRIFEAVFQCTLEM 840
             F+PP++D +L DY R  VP ARE +VLS  A IV+K +  +  +VP+IF+AVF+CTL+M
Sbjct: 767  NFIPPLLDAILLDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDM 826

Query: 841  ITKNFEDYPEHRLKFFSLLCAIATHCFHALICLSSQQLKFVMDSIIWAFRHTERNIAETG 900
            I KNFED+P+HRL F+ LL A+  HCF A + +   Q K V DS++WAF+HT RN+A+ G
Sbjct: 827  INKNFEDFPQHRLSFYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMG 886

Query: 901  LNLLLEMLKKF-QATEFCNQFYRTYFLTIEQEIFAVLTDTFHKPGFKLHVLVLQHLFCLA 959
            LN+L +ML+   Q       FY+TYF  I  +IF+V+TDT H  G   H ++L ++F L 
Sbjct: 887  LNILFKMLQNLDQHPGAAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLV 946

Query: 960  ETGALTEPLWDAATNPYPYPSNAAFVLEYTIKLLSTSFPNMTAAEVTQFVNGLFESTNDL 1019
            E   +T        N  P P N  F+ EY   LL ++F +++  +V  FV GLF    ++
Sbjct: 947  ENRKIT-------VNLGPIPDNMIFIQEYVASLLKSAFTHLSDNQVKVFVTGLFNLDENV 999

Query: 1020 STFKNHIRDFLVQSKEFSAQDNKDLYAEE----AAAQRERERQRMLSVPGLIAPSELQDE 1075
              FK H+RDFL+Q +E + +D+ DLY EE     A ++  + Q   ++PG++ P EL ++
Sbjct: 1000 QAFKEHLRDFLIQIREATGEDDSDLYLEEREAALAEEQSNKHQMQRNIPGMLNPHELPED 1059

Query: 1076 MLD 1078
            M D
Sbjct: 1060 MQD 1062


>XPO1_SCHPO (P14068) Exportin 1 (Chromosome region maintenance protein
            1) (Caffeine resistance protein 2)
          Length = 1078

 Score =  978 bits (2528), Expect = 0.0
 Identities = 495/1077 (45%), Positives = 721/1077 (65%), Gaps = 16/1077 (1%)

Query: 4    EKLRDLSQPIDVPLLDATVAAFY-GTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQ 62
            E +    + +DV LLD  V  FY G G+++Q+  A Q+L   Q +PD W Q   IL+ ++
Sbjct: 2    EGILAFDRELDVALLDRVVQTFYQGVGAEQQQ--AQQVLTQFQAHPDAWSQAYSILEKSE 59

Query: 63   NLNTKFFALQVLEGVIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLN 122
               TK+ AL VL+ +I  RW  LP EQR G++N+I  ++++ S +E   + ++ ++NKL+
Sbjct: 60   YPQTKYIALSVLDKLITTRWKMLPKEQRLGIRNYIVAVMIKNSSDETVLQQQKTFLNKLD 119

Query: 123  IILVQILKHEWPLRWRSFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKI 182
            + LVQILK EWP  W +FIP++V A+KT+ ++CEN M +L+LLSEE+FD+S  +MTQ K 
Sbjct: 120  LTLVQILKQEWPHNWPNFIPEIVQASKTNLSLCENNMIVLRLLSEEIFDYSAEQMTQLKT 179

Query: 183  KELKQSLNSEFQLIHELCLYVLSASQRAELIRATLSTLHAFLSWIPLGYIFESPLLETLL 242
            K LK  +  EF  I +LC  +L  +Q+  LI+ATL TL  FL+WIPLGYIFE+ ++E + 
Sbjct: 180  KNLKNQMCGEFAEIFQLCSQILERAQKPSLIKATLGTLLRFLNWIPLGYIFETNIVELIT 239

Query: 243  -KFFPLPVYRNLTLKCLIEVAALQFGDYYDTQYTKMYNIFMVQLQTILLPTTNIPEAYAQ 301
             +F  +P +RN+T++CL E+A+L     Y+ ++  M+N+ M  + ++L   T+  EAY +
Sbjct: 240  NRFLNVPDFRNVTIECLTEIASLTSQPQYNDKFVTMFNLVMTSVNSMLPLQTDFREAYEE 299

Query: 302  GSSEEQTFIQNLALFFTSFYKVHIRILESTQENIAALLSGLEYLINISYVDDTEVFKVCL 361
             S+ EQ FIQNLALF  +F+  H+R LE+  EN   LL+   YL+NIS +++ E+FK+CL
Sbjct: 300  SSTNEQDFIQNLALFLCAFFSSHLRPLENP-ENQEVLLNAHSYLLNISRINEREIFKICL 358

Query: 362  DYWNILVSELFEPHRSLENPAAAATNMLGNQQAPLMPPGMVDGLGSQLLQRRQLYAGPMS 421
            +YW+ LV++L+E    ++    +  N L N  +P         + + L  R+ +Y   +S
Sbjct: 359  EYWSKLVAQLYE---EMQQIPMSEMNPLLNLSSPTSLISSNPNMLANLPLRKHIYKDILS 415

Query: 422  KLRTLMICRMAKPEEVLIIEDENGNIVRETLKDNDVLVQYKIMRETLIYLSHLDHDDTER 481
             LR +MI  M KPEEVLI+E++ G IVRE +K+ D +  YK MRE L+YL+HLD  DTE 
Sbjct: 416  TLRLVMIENMVKPEEVLIVENDEGEIVREFVKETDTITLYKSMREVLVYLTHLDVVDTEI 475

Query: 482  QMLRKLSKQLGGEDWTWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGK 541
             M  KL++ + G +W+W NLNTLCWAIGSISG+M E+ E RFLV VI+DLL LCE  +GK
Sbjct: 476  VMTEKLARIVVGTEWSWQNLNTLCWAIGSISGAMNEEMEKRFLVNVIKDLLGLCEMKRGK 535

Query: 542  DNKAVIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQK 601
            DNKAV+ASNIMYVVGQYPRFL+AHWKFLKTVVNKLFEFMHE H GVQDMACDTF+KI QK
Sbjct: 536  DNKAVVASNIMYVVGQYPRFLKAHWKFLKTVVNKLFEFMHEYHEGVQDMACDTFIKIAQK 595

Query: 602  CKRKFVITQLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYL 661
            C+R FV  QLGE EPF++E++  L+ T  DL P Q HTFYE+ G M+ A+     ++  +
Sbjct: 596  CRRHFVAQQLGETEPFINEIIRNLAKTTEDLTPQQTHTFYEACGYMISAQPQKHLQERLI 655

Query: 662  QRLMHLPNQKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFLPQISLIF 721
              LM LPNQ W  I+ QA QN   L D   ++ + N+L+TN +  +S+G+ F PQI+  +
Sbjct: 656  FDLMALPNQAWENIVAQAAQNAQVLGDPQTVKILANVLKTNVAACTSIGSGFYPQIAKNY 715

Query: 722  LDMLNVYRMYSELISKSIAEGGPYASRTSFVKLLRSVKRETLKLIETFLDKAEDQPQIGK 781
            +DML +Y+  S LIS+ +A  G  A++T  V+ LR++K+E LKL++ ++ +AED   +G 
Sbjct: 716  VDMLGLYKAVSGLISEVVAAQGNIATKTPHVRGLRTIKKEILKLVDAYISRAEDLELVGN 775

Query: 782  QFVPPMMDPVLGDYARNVPDARESEVLSLFATIVNKYKAAMVEDVPRIFEAVFQCTLEMI 841
              +P + + VL DY +NVPDAR++EVL+L  TIVN+    + + +P + +AVF CTLEMI
Sbjct: 776  TLIPALFEAVLLDYLQNVPDARDAEVLNLITTIVNQLSELLTDKIPLVLDAVFGCTLEMI 835

Query: 842  TKNFEDYPEHRLKFFSLLCAIATHCFHALICLSSQQLKFVMDSIIWAFRHTERNIAETGL 901
            +K+F +YPEHR  FF LL AI  +CF AL+ + + Q K V++SI+W+F+H  R+I ETGL
Sbjct: 836  SKDFSEYPEHRAAFFQLLRAINLNCFPALLNIPAPQFKLVINSIVWSFKHVSRDIQETGL 895

Query: 902  NLLLEMLKKF--QATEFCNQFYRTYFLTIEQEIFAVLTDTFHKPGFKLHVLVLQHLFCLA 959
            N+LLE++        +  N F++TY++++ Q+I  VLTD+ HK GFKL  L+L  LF L 
Sbjct: 896  NILLELINNMASMGPDVSNAFFQTYYISLLQDILYVLTDSDHKSGFKLQSLILARLFYLV 955

Query: 960  ETGALTEPLWDAATNPYPYPSNAAFVLEYTIKLLSTSFPNMTAAEVTQFVNGLFESTNDL 1019
            E+  +T PL+D +  P    +N  F+ +Y + LL T+FP++   ++ +FV  +     D 
Sbjct: 956  ESNQITVPLYDPSQFPQEM-NNQLFLRQYIMNLLVTAFPHLQPIQIQEFVQTVLALNQDS 1014

Query: 1020 STFKNHIRDFLVQSKEFSAQDNKDLYAE----EAAAQRERERQRMLSVPGLIAPSEL 1072
              FK  +RDFL+Q KEF   DN +LY E    E AAQ++ + ++ ++VPG+I P ++
Sbjct: 1015 IKFKLALRDFLIQLKEFGG-DNAELYLEEKEQELAAQQKAQLEKAMTVPGMIKPVDM 1070


>XPO1_YEAST (P30822) Exportin 1 (Chromosome region maintenance protein
            1)
          Length = 1084

 Score =  856 bits (2211), Expect = 0.0
 Identities = 451/1087 (41%), Positives = 671/1087 (61%), Gaps = 20/1087 (1%)

Query: 4    EKLRDLSQPIDVPLLDATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQN 63
            E + D S  +D+ LLD  V+ FY  GS  Q+  A +IL   Q+NPD W +   ILQ + N
Sbjct: 2    EGILDFSNDLDIALLDQVVSTFY-QGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTN 60

Query: 64   LNTKFFALQVLEGVIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNI 123
              +KF AL +L+ +I  +W  LP + R G++NF+  +I+ +  ++  F+ ++  +NK ++
Sbjct: 61   PQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDL 120

Query: 124  ILVQILKHEWPLRWRSFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKIK 183
             LVQILK EWP  W  FIP+L+ ++ +S  +CEN M +LKLLSEEVFDFS  +MTQ K  
Sbjct: 121  TLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKAL 180

Query: 184  ELKQSLNSEFQLIHELCLYVLSASQRAELIRATLSTLHAFLSWIPLGYIFESPLLETL-L 242
             LK S++ EF+ I +LC  VL     + LI ATL +L  +L WIP  YI+E+ +LE L  
Sbjct: 181  HLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLST 240

Query: 243  KFFPLPVYRNLTLKCLIEVAAL---QFGDYYDTQYTKMYNIFMVQLQTILLPTT-NIPEA 298
            KF   P  R +TLKCL EV+ L   Q  D    Q    +   + Q+ T ++P T ++   
Sbjct: 241  KFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKAT 300

Query: 299  YAQGSSEEQTFIQNLALFFTSFYKVHIRILESTQENIAALLSGLEYLINISYVDDTEVFK 358
            YA  +  +Q+F+Q+LA+F T++   +  +LES +     LL+  +YLI +S +++ E+FK
Sbjct: 301  YANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFK 360

Query: 359  VCLDYWNILVSELFEPHRSLENPAAAATNML----GNQQAPLMPPGMVDGLGSQLLQRRQ 414
              LDYW+ LV++LF   + L  PA   + ++    G+Q        +      +   ++ 
Sbjct: 361  TTLDYWHNLVADLFYEVQRL--PATEMSPLIQLSVGSQAISTGSGALNPEYMKRFPLKKH 418

Query: 415  LYAGPMSKLRTLMICRMAKPEEVLIIEDENGNIVRETLKDNDVLVQYKIMRETLIYLSHL 474
            +Y    S+LR ++I  M +PEEVL++E++ G IVRE +K++D +  YK  RE L+YL+HL
Sbjct: 419  IYEEICSQLRLVIIENMVRPEEVLVVENDEGEIVREFVKESDTIQLYKSEREVLVYLTHL 478

Query: 475  DHDDTERQMLRKLSKQLGGEDWTWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNL 534
            +  DTE  M+ KL++Q+ G +W+W+N+NTL WAIGSISG+M ED E RF+V VI+DLL+L
Sbjct: 479  NVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLDL 538

Query: 535  CEFTKGKDNKAVIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHESHPGVQDMACDT 594
                +GKDNKAV+AS+IMYVVGQYPRFL+AHW FL+TV+ KLFEFMHE+H GVQDMACDT
Sbjct: 539  TVKKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDT 598

Query: 595  FLKIVQKCKRKFVITQLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDS 654
            F+KIVQKCK  FVI Q  E+EPF+  ++  +  T  DL+P Q+HTFY++ G ++  E   
Sbjct: 599  FIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSV 658

Query: 655  QKRDEYLQRLMHLPNQKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFL 714
             +R+  L  LM LPN  W  I+ Q+  N   L D + ++ + NI++TN +V +S+G  F 
Sbjct: 659  AERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFY 718

Query: 715  PQISLIFLDMLNVYRMYSELISKSIAEGGPYASRTSFVKLLRSVKRETLKLIETFLDKAE 774
            PQ+  I+ +ML +YR  S +IS  +A  G  A++T  V+ LR++K+E LKL+ET++ KA 
Sbjct: 719  PQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKAR 778

Query: 775  DQPQIGKQFVPPMMDPVLGDYARNVPDARESEVLSLFATIVNKYKAAMVEDVPRIFEAVF 834
            +   + K  V P+++ VL DY  NVPDAR++EVL+   T+V K    + + V  I ++VF
Sbjct: 779  NLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVF 838

Query: 835  QCTLEMITKNFEDYPEHRLKFFSLLCAIATHCFHALICLSSQQLKFVMDSIIWAFRHTER 894
            +CTL+MI K+F +YPEHR++F+ LL  I    F A + L     K  +D+I WAF+H  R
Sbjct: 839  ECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNR 898

Query: 895  NIAETGLNLLLEMLKKFQA---TEFCNQFYRTYFLTIEQEIFAVLTDTFHKPGFKLHVLV 951
            ++   GL + L+++K  +      F N+F++ YF     E F VLTD+ HK GF    L+
Sbjct: 899  DVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALL 958

Query: 952  LQHLFCLAETGALTEPLWDAATNPYPYPSNAAFVLEYTIKLLSTSFPNMTAAEVTQFVNG 1011
            L  L  L     ++ PL+  A  P    SN  ++ +Y   +LS +FP++T+ ++  F++ 
Sbjct: 959  LMKLISLVYDNKISVPLYQEAEVPQG-TSNQVYLSQYLANMLSNAFPHLTSEQIASFLSA 1017

Query: 1012 LFESTNDLSTFKNHIRDFLVQSKEFSAQDNKDLYAEE----AAAQRERERQRMLSVPGLI 1067
            L +   DL  FK  +RDFLVQ KE        L+AE+       Q   ER++   + GL+
Sbjct: 1018 LTKQYKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAEDKENALMEQNRLEREKAAKIGGLL 1077

Query: 1068 APSELQD 1074
             PSEL D
Sbjct: 1078 KPSELDD 1084


>YNR7_SCHPO (Q9USZ2) Hypothetical protein C11G11.07 in chromosome II
          Length = 955

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 64/291 (21%), Positives = 121/291 (40%), Gaps = 23/291 (7%)

Query: 20  ATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHIL-QNTQNLNTKFFALQVLEGVI 78
           + +A  Y    +EQ+  A+  L + Q +P  W     IL Q+  ++  K FA Q L   I
Sbjct: 6   SALATLYANTDREQKLQANNYLEEFQKSPAAWQICFSILNQDDSSIEAKLFAAQTLRQKI 65

Query: 79  KYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEWPLRWR 138
            Y ++ LP E     +N +  + +      A+    R  +  L + +  I  H     W 
Sbjct: 66  VYDFHQLPKETHIEFRNSLLQLFL------AAKDSPRPLLVSLAVCMAAIALHM--TEWH 117

Query: 139 SFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKIK-ELKQSLNSEFQLIH 197
           + I D+  A  + +      +  L +L EE  D  +  ++ +++   + + L      + 
Sbjct: 118 NVIADVFQACSSKDPSGRCVLQFLSVLPEEASDPRKTSLSWEELCIRVDELLRDNGPAVL 177

Query: 198 ELCLYVLSA-----SQRAELIRATLSTLHAFLSWIPLGYIFESPLLETLLKFFPLPVYRN 252
           EL +  + A     S  +  +   L++L ++L  IPL  +  SPL+E   +     +  +
Sbjct: 178 ELLVQYVDAVRASGSPSSADLGLVLTSLISWLREIPLDKVMASPLIELAFR----SLDDD 233

Query: 253 LTLKCLIEVAALQFGDYYDTQYTK----MYNIFMVQLQTILLPTTNIPEAY 299
           L L+  +E     F +  D   T     M    +++LQ  L+   + PE +
Sbjct: 234 LLLEDAVEFLCALFNETKDVDETTDAILMLYPRLLELQPKLIAACDDPETF 284



 Score = 32.3 bits (72), Expect = 7.1
 Identities = 40/179 (22%), Positives = 81/179 (44%), Gaps = 24/179 (13%)

Query: 482 QMLRKLSKQLGGEDWTWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGK 541
           Q+++ L  +  G  + W ++    +A+ +I G M+   E++ +  + + L  L E     
Sbjct: 430 QLIKVLKIKESGLPYYWQDVEAPLFALRAI-GRMVPANEDQVIGSLFQILPQLPE----- 483

Query: 542 DNKAVIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQK 601
           +NK   A+ +   +G+Y  +   H +FL+  +N +      ++  VQ  A          
Sbjct: 484 NNKVRYAATLF--LGRYTEWTAQHSEFLELQLNYISAGFEVANKEVQSAAAQALKHFCYD 541

Query: 602 CKRKFV--ITQLG----------ENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMV 648
           C+ + V  ++QL             +P + E+  GL+  IVD++P  +   Y+SV S +
Sbjct: 542 CREQLVGHLSQLHMFYLNAKTYLAPDPLM-EVAQGLA-HIVDIQP--VANVYQSVHSFL 596


>TNP1_MOUSE (Q8BFY9) Transportin 1 (Importin beta-2) (Karyopherin
           beta-2)
          Length = 890

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 67/312 (21%), Positives = 137/312 (43%), Gaps = 53/312 (16%)

Query: 440 IEDENGNIVRETLKDNDVLVQYKIMR---ETLIYLSHLDHDDTERQMLRKLSKQLGGEDW 496
           IE+E+ +   + + D+D +  + + +     L  L+++  D+    +L  L + L   +W
Sbjct: 354 IEEEDDD--DDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEW 411

Query: 497 TWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGKDNKAVIASNIMYVVG 556
                  L   +G+I+   M+     +L  +I  L+         D KA++ S   + + 
Sbjct: 412 VVKESGIL--VLGAIAEGCMQGMIP-YLPELIPHLIQCLS-----DKKALVRSITCWTLS 463

Query: 557 QYPRFLRAHW-------KFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQKCKRKFVIT 609
           +Y     AHW        +LK ++ +L + + +S+  VQ+ AC  F  + ++   + V  
Sbjct: 464 RY-----AHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV-- 516

Query: 610 QLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYLQRLMHLPN 669
                 P+++ +L  L       +   +   Y+++G++  +      + EY+Q LM    
Sbjct: 517 ------PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLI 570

Query: 670 QKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFLPQISLIFLDMLNVYR 729
           QKW           + LKD D  + +  +L+  +SVA++L + FLP           VY+
Sbjct: 571 QKW-----------NMLKDED--KDLFPLLECLSSVATALQSGFLPYCE-------PVYQ 610

Query: 730 MYSELISKSIAE 741
               L+ K++A+
Sbjct: 611 RCVNLVQKTLAQ 622


>TNP1_HUMAN (Q92973) Transportin 1 (Importin beta-)2 (Karyopherin
           beta-2) (M9 region interaction protein) (MIP)
          Length = 890

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 67/312 (21%), Positives = 137/312 (43%), Gaps = 53/312 (16%)

Query: 440 IEDENGNIVRETLKDNDVLVQYKIMR---ETLIYLSHLDHDDTERQMLRKLSKQLGGEDW 496
           IE+E+ +   + + D+D +  + + +     L  L+++  D+    +L  L + L   +W
Sbjct: 354 IEEEDDD--DDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEW 411

Query: 497 TWNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGKDNKAVIASNIMYVVG 556
                  L   +G+I+   M+     +L  +I  L+         D KA++ S   + + 
Sbjct: 412 VVKESGIL--VLGAIAEGCMQGMIP-YLPELIPHLIQCLS-----DKKALVRSITCWTLS 463

Query: 557 QYPRFLRAHW-------KFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQKCKRKFVIT 609
           +Y     AHW        +LK ++ +L + + +S+  VQ+ AC  F  + ++   + V  
Sbjct: 464 RY-----AHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV-- 516

Query: 610 QLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYLQRLMHLPN 669
                 P+++ +L  L       +   +   Y+++G++  +      + EY+Q LM    
Sbjct: 517 ------PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLI 570

Query: 670 QKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFLPQISLIFLDMLNVYR 729
           QKW           + LKD D  + +  +L+  +SVA++L + FLP           VY+
Sbjct: 571 QKW-----------NMLKDED--KDLFPLLECLSSVATALQSGFLPYCE-------PVYQ 610

Query: 730 MYSELISKSIAE 741
               L+ K++A+
Sbjct: 611 RCVNLVQKTLAQ 622


>TNP2_HUMAN (O14787) Transportin 2 (Karyopherin beta-2b)
          Length = 897

 Score = 57.0 bits (136), Expect = 3e-07
 Identities = 69/315 (21%), Positives = 133/315 (41%), Gaps = 51/315 (16%)

Query: 441 EDENGNIVRETLKDNDVLVQYKIMR---ETLIYLSHLDHDDTERQMLRKLSKQLGGEDWT 497
           E  +G+   E   D+D L  + + +     L  L+++  ++    +L  L   L   +W 
Sbjct: 350 ERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWV 409

Query: 498 WNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGKDNKAVIASNIMYVVGQ 557
                 L   +G+I+   M+     +L  +I  L+         D KA++ S   + + +
Sbjct: 410 VKESGIL--VLGAIAEGCMQGMVP-YLPELIPHLIQCLS-----DKKALVRSIACWTLSR 461

Query: 558 YPRFLRAHW-------KFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQKCKRKFVITQ 610
           Y     AHW         LK ++ +L + + + +  VQ+ AC  F  + ++   + V   
Sbjct: 462 Y-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELV--- 513

Query: 611 LGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYLQRLMHLPNQ 670
                P++S +L  L       +   +   Y+++G++  +      + EY+Q+LM    Q
Sbjct: 514 -----PYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQ 568

Query: 671 KWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFLPQISLIFLDMLNVYRM 730
           KW E           LKD D  + +  +L+  +SVA++L + FLP           VY+ 
Sbjct: 569 KWNE-----------LKDED--KDLFPLLECLSSVATALQSGFLPYCE-------PVYQR 608

Query: 731 YSELISKSIAEGGPY 745
              L+ K++A+   Y
Sbjct: 609 CVTLVQKTLAQAMMY 623


>TNP2_MOUSE (Q99LG2) Transportin 2 (Karyopherin beta-2b)
          Length = 887

 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 50/211 (23%), Positives = 94/211 (43%), Gaps = 40/211 (18%)

Query: 542 DNKAVIASNIMYVVGQYPRFLRAHW-------KFLKTVVNKLFEFMHESHPGVQDMACDT 594
           D KA++ S   + + +Y     AHW         LK ++ +L + + + +  VQ+ AC  
Sbjct: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500

Query: 595 FLKIVQKCKRKFVITQLGENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDS 654
           F  + ++   + V        P++S +L  L       +   +   Y+++G++  +    
Sbjct: 501 FATLEEEACTELV--------PYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552

Query: 655 QKRDEYLQRLMHLPNQKWLEIIGQARQNVDFLKDHDVIRTVLNILQTNTSVASSLGTYFL 714
             + EY+Q+LM    QKW E           LKD D  + +  +L+  +SVA++L + FL
Sbjct: 553 LNQPEYIQKLMPPLIQKWNE-----------LKDED--KDLFPLLECLSSVATALQSGFL 599

Query: 715 PQISLIFLDMLNVYRMYSELISKSIAEGGPY 745
           P           VY+    L+ K++A+   Y
Sbjct: 600 PYCE-------PVYQRCVTLVQKTLAQAMMY 623


>XPOT_HUMAN (O43592) Exportin T (tRNA exportin) (Exportin(tRNA))
          Length = 962

 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 52/236 (22%), Positives = 98/236 (41%), Gaps = 11/236 (4%)

Query: 34  RTAADQILRDLQNNPDMWLQVMHIL--QNTQNLNTKFFALQVLEGVIKYRWNALPLEQRD 91
           R  A      L+ +PD W      L  +   + + KFF  QVLE  +KY+++ L   Q+ 
Sbjct: 18  RQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEHQVKYKYSELTTVQQQ 77

Query: 92  GMKNFISDIIVQLSGNEASFRMERLYV-NKLNIILVQILKHEWPLRWRSFIPDLVSAAKT 150
            ++     +I  L     + + E+ ++ NK   +   +   E+  +W  F  D++S    
Sbjct: 78  LIRE---TLISWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWPKFFFDILSVVDL 134

Query: 151 SETICENCMAILKLLSEEVFDFSRGEMTQQKIKE--LKQSLNSE-FQLIHELCLYVLSAS 207
           +    +  + IL  +  E+ D      +++  +   +K ++  +    + E    +L   
Sbjct: 135 NPRGVDLYLRILMAIDSELVDRDVVHTSEEARRNTLIKDTMREQCIPNLVESWYQILQNY 194

Query: 208 Q--RAELIRATLSTLHAFLSWIPLGYIFESPLLETLLKFFPLPVYRNLTLKCLIEV 261
           Q   +E+    L  + A++SWI L  I     +  LL    + V R     CL EV
Sbjct: 195 QFTNSEVTCQCLEVVGAYVSWIDLSLIANDRFINMLLGHMSIEVLREEACDCLFEV 250


>XPO7_MOUSE (Q9EPK7) Exportin 7 (Ran-binding protein 16)
          Length = 1087

 Score = 38.1 bits (87), Expect = 0.13
 Identities = 62/307 (20%), Positives = 116/307 (37%), Gaps = 53/307 (17%)

Query: 26  YGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQNLNTKFFALQVLEGVIKYRWNAL 85
           Y T     R  A++ L +  N+PD   +   +L+   +  ++  A   L  ++    N L
Sbjct: 19  YETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPL 78

Query: 86  PLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEW------PLRWRS 139
           PLEQR  ++N++ + +          ++       L  +  +I K  W         +R+
Sbjct: 79  PLEQRIDIRNYVLNYLATRP------KLATFVTQALIQLYARITKLGWFDCQKDDYVFRN 132

Query: 140 FIPDLVSAAKTSETICENCMAILKLLSEE---------------------------VFDF 172
            I D+    + S   C   + IL  L+ E                           +F  
Sbjct: 133 AITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDSSLFDIFTL 192

Query: 173 SRGEMTQQKIKELKQSLNSEFQLIHELCLYVLSASQRA---ELIRATLSTLHAFLSWIPL 229
           S   + Q   K L  +LN E Q  H L + +L  +      + I  +       L  + +
Sbjct: 193 SCNLLKQASGKNL--NLNDESQ--HGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQI 248

Query: 230 GYIFESPLLE--TLLKFFPL-----PVYRNLTLKCLIEVAALQFGDYYDTQYTKMYNIFM 282
              + S  L+  TL  FF L     P +  L L CL+++A+++   + + +  K  +  +
Sbjct: 249 PTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLV 308

Query: 283 VQLQTIL 289
             ++ IL
Sbjct: 309 DGVKRIL 315


>XPO7_HUMAN (Q9UIA9) Exportin 7 (Ran-binding protein 16)
          Length = 1087

 Score = 38.1 bits (87), Expect = 0.13
 Identities = 62/307 (20%), Positives = 116/307 (37%), Gaps = 53/307 (17%)

Query: 26  YGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQNLNTKFFALQVLEGVIKYRWNAL 85
           Y T     R  A++ L +  N+PD   +   +L+   +  ++  A   L  ++    N L
Sbjct: 19  YETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPL 78

Query: 86  PLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEW------PLRWRS 139
           PLEQR  ++N++ + +          ++       L  +  +I K  W         +R+
Sbjct: 79  PLEQRIDIRNYVLNYLATRP------KLATFVTQALIQLYARITKLGWFDCQKDDYVFRN 132

Query: 140 FIPDLVSAAKTSETICENCMAILKLLSEE---------------------------VFDF 172
            I D+    + S   C   + IL  L+ E                           +F  
Sbjct: 133 AITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDSSLFDIFTL 192

Query: 173 SRGEMTQQKIKELKQSLNSEFQLIHELCLYVLSASQRA---ELIRATLSTLHAFLSWIPL 229
           S   + Q   K L  +LN E Q  H L + +L  +      + I  +       L  + +
Sbjct: 193 SCNLLKQASGKNL--NLNDESQ--HGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQI 248

Query: 230 GYIFESPLLE--TLLKFFPL-----PVYRNLTLKCLIEVAALQFGDYYDTQYTKMYNIFM 282
              + S  L+  TL  FF L     P +  L L CL+++A+++   + + +  K  +  +
Sbjct: 249 PTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLV 308

Query: 283 VQLQTIL 289
             ++ IL
Sbjct: 309 DGVKRIL 315


>YKX1_SCHPO (O14116) Hypothetical protein C328.01c in chromosome I
          Length = 1234

 Score = 37.7 bits (86), Expect = 0.17
 Identities = 34/158 (21%), Positives = 75/158 (46%), Gaps = 22/158 (13%)

Query: 30  SKEQRTAADQILRDLQNN---PDMWLQVMHILQNT-QNLNTKF-------FALQVLEGVI 78
           S+E R +A Q+L +L+++   P + +Q++ + +    +L  K        F+L + E  +
Sbjct: 22  SRETRFSAQQLLDELKDSYSSPSVAIQLLELNEQAFSSLGCKLDIHIVQHFSLSLFETSV 81

Query: 79  KYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEWPLRWR 138
              W +   ++++ + +F+  I ++   N  S    R   +KL  + ++I K +W   WR
Sbjct: 82  GMNWKSFSNKEKESVTSFLCKISLE-DNNLLSVHFVR---SKLASVFIEIAKRDWYNTWR 137

Query: 139 ----SFIPDLVSAAKTSETICENCMAILKLLSEEVFDF 172
               SF+  L S +     +      IL+ + E+++ +
Sbjct: 138 EEFDSFLQSLWSLSLQHRQLSS---LILRGIMEDLYQY 172


>LOS1_YEAST (P33418) LOS1 protein
          Length = 1100

 Score = 36.2 bits (82), Expect = 0.49
 Identities = 59/305 (19%), Positives = 128/305 (41%), Gaps = 39/305 (12%)

Query: 4   EKLRDLSQPIDVPLLDATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQN 63
           E+++ L   ++ P  D          +K Q       ++  +N  ++++ ++ I +N+ +
Sbjct: 3   ERIQQLVNAVNDPRSDVA--------TKRQAIELLNGIKSSENALEIFISLV-INENSND 53

Query: 64  LNTKFFALQVLEGVIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNI 123
           L  KF+ L  L  ++    NA P             +  Q+ GN+ + ++    +NK++ 
Sbjct: 54  L-LKFYGLSTLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQT-KLPDFLMNKISE 111

Query: 124 ILVQILKHEWP----LRWRSFIPDLVSA-------AKTSETICENCMAILK-------LL 165
           +L  +    +      +W SF  DL+S        + TS +   N +  L+       ++
Sbjct: 112 VLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLGLEFFNKLCLMI 171

Query: 166 SEEVFD--FSRGEMTQQKIKELKQSL-NSEFQLIHELCLYVLS-----ASQRAELIRATL 217
           + E+ D  F R + +Q K   +K  + +++   +  +    L       SQ   LI +TL
Sbjct: 172 NSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQIVSQCPGLINSTL 231

Query: 218 STLHAFLSWIPLGYIFESP--LLETLLKFFPLPVYRNLTLKCLIEVAALQFGDYYDTQYT 275
             + +F+SWI +  I ++    L+ + KF  L   +     C++ + + +        + 
Sbjct: 232 DCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILAIISKKMKPMDKLAFL 291

Query: 276 KMYNI 280
            M N+
Sbjct: 292 NMINL 296


>IMB2_SCHPO (O14089) Putative importin beta-2 subunit (Karyopherin
           beta-2 subunit) (Importin 104) (Transportin) (TRN)
          Length = 910

 Score = 35.4 bits (80), Expect = 0.83
 Identities = 43/241 (17%), Positives = 98/241 (39%), Gaps = 28/241 (11%)

Query: 441 EDENGNIVRETLKDNDVLVQYKIMRETLIYLSHLDHDDTERQM---LRKLSKQLGGEDWT 497
           EDE+ +   E  +D+D  + + + + +   L  L     +R +   L  L + L  EDW 
Sbjct: 373 EDEDDD---EFDEDDDAFMDWNLRKCSAAALDVLSSFWKQRLLEIILPHLKQSLTSEDWK 429

Query: 498 WNNLNTLCWAIGSISGSMMEDQENRFLVMVIRDLLNLCEFTKGKDNKAVIASNIMYVVGQ 557
                 L  A+G+I+   M+    ++L  +    L+L +       K ++ +   + +G+
Sbjct: 430 VQEAGVL--AVGAIAEGCMDGMV-QYLPELYPYFLSLLD-----SKKPLVRTITCWTLGR 481

Query: 558 YPRFLRA------HWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQKCKRKFVITQL 611
           Y ++           K+   ++  L   + +++  VQ+  C  F  + ++     V    
Sbjct: 482 YSKWASCLESEEDRQKYFVPLLQGLLRMVVDNNKKVQEAGCSAFAILEEQAGPSLV---- 537

Query: 612 GENEPFVSELLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYLQRLMHLPNQK 671
               P++  +L+ L+      +   +   Y++V ++      +     Y++ L+    QK
Sbjct: 538 ----PYLEPILTNLAFAFQKYQRKNVLILYDAVQTLADYVGSALNDKRYIELLITPLLQK 593

Query: 672 W 672
           W
Sbjct: 594 W 594


>YAA2_SCHPO (Q09796) Hypothetical protein C22G7.02 in chromosome I
          Length = 990

 Score = 34.3 bits (77), Expect = 1.9
 Identities = 27/106 (25%), Positives = 45/106 (41%), Gaps = 6/106 (5%)

Query: 561 FLRAHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKIVQKCKRKFVITQLGENEPFVSE 620
           FL+ H ++L   +  LF+ +H S   +Q     +   +   C    ++T++      V E
Sbjct: 541 FLQNHPQYLNISLPVLFDALHISETSIQMTVSRSIHTLCTTCA-SHLLTEIDGFMAVVEE 599

Query: 621 LLSGLSTTIVDLEPHQIHTFYESVGSMVQAESDSQKRDEYLQRLMH 666
           L   L        P  +   Y SVG + Q   D + R  YL RL++
Sbjct: 600 LTPKLVYV-----PSVLEKIYSSVGYVTQRIEDIELRISYLMRLLN 640


>TPO3_MOUSE (Q6P2B1) Transportin 3
          Length = 923

 Score = 34.3 bits (77), Expect = 1.9
 Identities = 75/372 (20%), Positives = 138/372 (36%), Gaps = 41/372 (11%)

Query: 17  LLDATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQNLNTKFFALQVLEG 76
           L+   V A Y       +  A   L +LQ +   W     +LQ  Q++ + +FA Q ++ 
Sbjct: 10  LVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQDVESCYFAAQTMKM 69

Query: 77  VIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEWPLR 136
            I+  +  LP +    +++ +   I  L        +  + V +L + +   L  + P  
Sbjct: 70  KIQTSFYELPTDSHASLRDSLLTHIQNLKD------LSPVIVTQLALAIAD-LALQMP-S 121

Query: 137 WRSFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKIKELKQSLNSEFQLI 196
           W+  +  LV       T     + IL +L EEV             + L+   N   ++I
Sbjct: 122 WKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHS-----------RSLRIGANRRTEII 170

Query: 197 HELCLY-------VLSASQRAELIRATLSTLHAFL-SWIPLGYIFESPLLET-LLKFFPL 247
            +L  Y       +++  ++A      L  +   L SW  LG +  + +    LL     
Sbjct: 171 EDLAFYSSTVVSLLMTCVEKAGTDEKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFE 230

Query: 248 PVYRNLTLKCLIEVA------ALQFGDYYDTQYTKMYNIFMVQLQTILLPTTNIPEAYAQ 301
            + ++ T   L E A      AL   +  +T       +F    Q +L   T    A A+
Sbjct: 231 VLQQDKTSSNLHEAASDCVCSALYAIENVETNLPLAMQLF----QGVLTLETAYHMAVAR 286

Query: 302 GSSEEQTFIQNLALFFTSFYKVHIRILESTQENIAALLSGLEYLINISYVDDTEVFKVCL 361
              E+   + N    FT   +  +  +  T       L  LE L+  +     EV ++  
Sbjct: 287 ---EDLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISF 343

Query: 362 DYWNILVSELFE 373
           ++W  L   L++
Sbjct: 344 NFWYRLGEHLYK 355


>TPO3_HUMAN (Q9Y5L0) Transportin 3 (Transportin-SR) (TRN-SR)
           (Importin 12)
          Length = 975

 Score = 34.3 bits (77), Expect = 1.9
 Identities = 75/372 (20%), Positives = 138/372 (36%), Gaps = 41/372 (11%)

Query: 17  LLDATVAAFYGTGSKEQRTAADQILRDLQNNPDMWLQVMHILQNTQNLNTKFFALQVLEG 76
           L+   V A Y       +  A   L +LQ +   W     +LQ  Q++ + +FA Q ++ 
Sbjct: 10  LVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQDVESCYFAAQTMKM 69

Query: 77  VIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERLYVNKLNIILVQILKHEWPLR 136
            I+  +  LP +    +++ +   I  L        +  + V +L + +   L  + P  
Sbjct: 70  KIQTSFYELPTDSHASLRDSLLTHIQNLKD------LSPVIVTQLALAIAD-LALQMP-S 121

Query: 137 WRSFIPDLVSAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKIKELKQSLNSEFQLI 196
           W+  +  LV       T     + IL +L EEV             + L+   N   ++I
Sbjct: 122 WKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHS-----------RSLRIGANRRTEII 170

Query: 197 HELCLY-------VLSASQRAELIRATLSTLHAFL-SWIPLGYIFESPLLET-LLKFFPL 247
            +L  Y       +++  ++A      L  +   L SW  LG +  + +    LL     
Sbjct: 171 EDLAFYSSTVVSLLMTCVEKAGTDEKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFE 230

Query: 248 PVYRNLTLKCLIEVA------ALQFGDYYDTQYTKMYNIFMVQLQTILLPTTNIPEAYAQ 301
            + ++ T   L E A      AL   +  +T       +F    Q +L   T    A A+
Sbjct: 231 VLQQDKTSSNLHEAASDCVCSALYAIENVETNLPLAMQLF----QGVLTLETAYHMAVAR 286

Query: 302 GSSEEQTFIQNLALFFTSFYKVHIRILESTQENIAALLSGLEYLINISYVDDTEVFKVCL 361
              E+   + N    FT   +  +  +  T       L  LE L+  +     EV ++  
Sbjct: 287 ---EDLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISF 343

Query: 362 DYWNILVSELFE 373
           ++W  L   L++
Sbjct: 344 NFWYRLGEHLYK 355


>CSE1_SCHPO (O13671) Importin-alpha re-exporter (Cellular apoptosis
           susceptibility protein homolog)
          Length = 967

 Score = 33.9 bits (76), Expect = 2.4
 Identities = 26/97 (26%), Positives = 44/97 (44%), Gaps = 16/97 (16%)

Query: 57  ILQNTQNLNTKFFALQVLEGVIKYRWNALPLEQRDGMKNFISDIIVQLSGNEASFRMERL 116
           + ++T ++N K  A    +  IK  W++      +G    ISD + +L   E    +  L
Sbjct: 42  VAEDTVDINIKLAASLYFKNYIKKHWDS-----EEGASIRISDEVAELIKRE----IINL 92

Query: 117 YVNKLNIILVQ-------ILKHEWPLRWRSFIPDLVS 146
            +    II VQ       I   ++P RW + +PDL+S
Sbjct: 93  MLKSTTIIQVQLGEVIGYIANFDFPDRWDTLLPDLIS 129


>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 719

 Score = 33.9 bits (76), Expect = 2.4
 Identities = 33/158 (20%), Positives = 60/158 (37%), Gaps = 17/158 (10%)

Query: 379 ENPAAAATNMLGNQQAPLMP---PGMVDG-LGSQLLQRRQLYAGPMSKLRTLMIC----- 429
           + PA++A    G  ++PL P   PG++DG LG Q L   Q   G M   ++L        
Sbjct: 150 QQPASSAYKQFGGSESPLQPAALPGLLDGSLGDQTLVGNQSSQGAMLSRQSLQCSSVPQS 209

Query: 430 -----RMAKPEEVLIIEDENGNIVRETLKDNDVLVQYKIMRETLIYLSHLDHDDTERQML 484
                R        +  +    ++ ++ ++    V+ K+      Y S ++H     Q  
Sbjct: 210 PNGGQRQTSGVGNYMYFERRPELLSKSTQEKAAAVKLKVEN---FYQSSVNHAIERNQRR 266

Query: 485 RKLSKQLGGEDWTWNNLNTLCWAIGSISGSMMEDQENR 522
            +L  QL    W+    N    ++G      +  +  R
Sbjct: 267 VELESQLLSHGWSEERKNRQLSSLGKKESQFLRLRRTR 304


>RYR1_PIG (P16960) Ryanodine receptor 1 (Skeletal muscle-type
            ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle
            calcium release channel)
          Length = 5035

 Score = 33.1 bits (74), Expect = 4.1
 Identities = 19/68 (27%), Positives = 35/68 (50%), Gaps = 4/68 (5%)

Query: 998  PNMTAAEVTQFVNGLFESTNDLSTFKNHIRDFLVQSK----EFSAQDNKDLYAEEAAAQR 1053
            PN +A E+ + V  +F   +    FK   ++F+VQ++     F   DNK   A+   + +
Sbjct: 3428 PNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMAKSGGSDQ 3487

Query: 1054 ERERQRML 1061
            ER +++ L
Sbjct: 3488 ERTKKKRL 3495


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.322    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,647,798
Number of Sequences: 164201
Number of extensions: 4880093
Number of successful extensions: 12720
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 12669
Number of HSP's gapped (non-prelim): 44
length of query: 1079
length of database: 59,974,054
effective HSP length: 121
effective length of query: 958
effective length of database: 40,105,733
effective search space: 38421292214
effective search space used: 38421292214
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)