BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0381.7
(297 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrie... 475 e-134
DIF1_CAEEL (Q27257) Protein dif-1 214 2e-55
MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrie... 201 2e-51
MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier ... 195 1e-49
MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrie... 195 1e-49
YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor 188 2e-47
COLT_DROME (Q9VQG4) Congested-like trachea protein 187 2e-47
ORT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solut... 181 1e-45
ORT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solut... 180 3e-45
ORT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solut... 180 4e-45
YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor 164 3e-40
YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c 158 1e-38
CACL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier... 157 4e-38
CACL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier... 155 9e-38
CRC1_YEAST (Q12289) Mitochondrial carnitine carrier 142 1e-33
AR13_NEUCR (Q01356) Amino acid transporter arg-13 141 2e-33
ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein 133 6e-31
ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1 122 1e-27
CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protei... 117 3e-26
ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2 115 1e-25
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine
carrier-like protein (A BOUT DE SOUFFLE)
(Carnitine/acylcarnitine translocase-like protein)
(CAC-like protein)
Length = 300
Score = 475 bits (1223), Expect = e-134
Identities = 238/300 (79%), Positives = 259/300 (86%), Gaps = 3/300 (1%)
Query: 1 MGDVAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAE 60
M D KDL +GT GGAAQL+VGHPFDTIKVKLQSQPTP PGQLPRY+GAIDAVKQT+A+E
Sbjct: 1 MADAWKDLASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASE 60
Query: 61 GPRGLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSF 120
G +GLYKGMGAPLATVAA NAVLFTVRGQME L RS G LT+ QQ GAGAG AVSF
Sbjct: 61 GTKGLYKGMGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSF 120
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAA---VAVKYGGPMDVARHVLRSEGGARGLFKGLVPT 177
L CPTELIKCRLQAQ LAG+ T + AVKYGGPMDVARHVLRSEGGARGLFKGL PT
Sbjct: 121 LACPTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPT 180
Query: 178 MAREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSV 237
AREVPGNA MF AYEA K+ LAGG DTS LG+GSLI+AGG+AGASFW VYPTDVVKSV
Sbjct: 181 FAREVPGNATMFAAYEAFKRFLAGGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSV 240
Query: 238 IQVDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSALG 297
+QVDDYK P+++GS+DAFR+IL SEG+KGLYKGFGPAM RSVPANAACFLAYEMTRS+LG
Sbjct: 241 LQVDDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMTRSSLG 300
>DIF1_CAEEL (Q27257) Protein dif-1
Length = 312
Score = 214 bits (545), Expect = 2e-55
Identities = 121/296 (40%), Positives = 172/296 (57%), Gaps = 8/296 (2%)
Query: 1 MGDVAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAE 60
M DV + AG GG+ +IVGHPFDT+KV++Q+ P P PG+ P+++GA+D VK+T++ E
Sbjct: 1 MSDVLLNFIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKE 60
Query: 61 GPRGLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSF 120
G LYKGM APL V+ L AV F + L ++ P +T Q GA AG+ +
Sbjct: 61 GFFALYKGMAAPLVGVSPLFAVFFGGCAVGKWLQQTDPSQEMTFIQNANAGALAGVFTTI 120
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
++ P E IKC LQ Q +G+A V Y GP+DV + L +GG +++G T+ R
Sbjct: 121 VMVPGERIKCLLQVQQ----AGSAGSGVHYDGPLDVVKK-LYKQGGISSIYRGTGATLLR 175
Query: 181 EVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ- 239
++P +AA YE K+ +G L G+ ++AGGLAG + W P DV+KS +Q
Sbjct: 176 DIPASAAYLSVYEYLKKKFSGEGAQRTLSPGATLMAGGLAGIANWGVCIPADVLKSRLQT 235
Query: 240 VDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSA 295
+ KYP G R +L EG + L+KGF P M R+ PANAACF E+T +A
Sbjct: 236 APEGKYP--DGIRGVLREVLREEGPRALFKGFWPVMLRAFPANAACFFGLELTLAA 289
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier
protein (Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 201 bits (511), Expect = 2e-51
Identities = 123/293 (41%), Positives = 162/293 (54%), Gaps = 12/293 (4%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGL 65
K+L AG FGG + VGHP DT+KV+LQ+QP +PGQ P YSG D ++TL EG GL
Sbjct: 12 KNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGL 71
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
Y+GM AP+ V + AV F G + L + HP L+ Q G +G+ + ++ P
Sbjct: 72 YRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPG 131
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
E IKC LQ Q A SG + KY G +D A+ L E G RG++KG V T+ R+VP +
Sbjct: 132 ERIKCLLQIQ---ASSGES----KYTGTLDCAKK-LYQEFGIRGIYKGTVLTLMRDVPAS 183
Query: 186 AAMFGAYEASKQLLA-GGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ-VDDY 243
F YE K + G S L ++VAGG+AG W P DV+KS Q
Sbjct: 184 GMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPG 243
Query: 244 KYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
KYP +G D R ++ EG+ LYKGF M R+ PANAACFL +E+ L
Sbjct: 244 KYP--NGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier
protein (Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 195 bits (496), Expect = 1e-49
Identities = 122/293 (41%), Positives = 156/293 (52%), Gaps = 12/293 (4%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGL 65
K+L AG FGG + VGHP DT+KV+LQ+QP +PGQ P YSG ID ++TL EG GL
Sbjct: 12 KNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGL 71
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
Y+GM AP+ V + AV F G + L + P LT Q G +G+ + ++ P
Sbjct: 72 YRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPG 131
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
E IKC LQ Q A SG KY G +D A+ L E G RG +KG T+ R+VP +
Sbjct: 132 ERIKCLLQIQ---ASSGKN----KYSGTLDCAKK-LYQEFGIRGFYKGTALTLMRDVPAS 183
Query: 186 AAMFGAYEASKQLLA-GGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ-VDDY 243
F YE K L G L ++VAGG G W P DV+KS Q
Sbjct: 184 GMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPG 243
Query: 244 KYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
KYP +G D R ++ EG+ LYKGF M R+ PANAACFL +E+ L
Sbjct: 244 KYP--NGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIPMKIL 294
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier
protein (Carnitine/acylcarnitine translocase) (CAC)
(mCAC)
Length = 301
Score = 195 bits (496), Expect = 1e-49
Identities = 122/293 (41%), Positives = 158/293 (53%), Gaps = 12/293 (4%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGL 65
K+L AG FGG + VGHP DT+KV+LQ+QP + GQ P YSG +D ++TL EG GL
Sbjct: 12 KNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGL 71
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
Y+GM AP+ V + AV F G + L + P L+ Q G +G+ + ++ P
Sbjct: 72 YRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPG 131
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
E IKC LQ Q A SG KY G +D A+ L E G RG +KG V T+ R+VP +
Sbjct: 132 ERIKCLLQIQ---ASSGEN----KYSGTLDCAKK-LYQEFGIRGFYKGTVLTLMRDVPAS 183
Query: 186 AAMFGAYEASKQLLA-GGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ-VDDY 243
F YE K L G S L ++VAGG AG W P DV+KS Q
Sbjct: 184 GMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPG 243
Query: 244 KYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
KYP +G D R ++ EG+ LYKGF M R+ PANAACFL +E+ L
Sbjct: 244 KYP--NGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFL 294
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor
Length = 307
Score = 188 bits (477), Expect = 2e-47
Identities = 116/301 (38%), Positives = 165/301 (54%), Gaps = 25/301 (8%)
Query: 4 VAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPR 63
V KDL AGT GG AQ++VG PFDT KV+LQ+ TP + A++ V++ LA EGPR
Sbjct: 25 VVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTP--------TTAMEVVRKLLANEGPR 76
Query: 64 GLYKGMGAPLATVAALNAVLFTVRGQMEALFR---SHPGASLTVHQQVFCGAGAGLAVSF 120
G YKG PL V A ++ F V M+ F + ++L++ Q CG G+ SF
Sbjct: 77 GFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHHRNADMSSTLSLPQYYACGVTGGIVNSF 136
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
L P E ++ RLQ Q+ GSGT A ++ GP++ + + + + L +GL PT+ R
Sbjct: 137 LASPIEHVRIRLQTQT---GSGTNA---EFKGPLECIKKLRHN----KALLRGLTPTILR 186
Query: 181 EVPGNAAMFGAYEA---SKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSV 237
E G F YEA ++ G + + L + G L+G + W VYP DV+KSV
Sbjct: 187 EGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVIKSV 246
Query: 238 IQVDDYKYPKFSGSIDAFRRIL-ASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
+Q D+ + PKF SI + + L A+ GI +KGFGP M R+ PAN A F +E+ L
Sbjct: 247 MQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATFELAMRLL 306
Query: 297 G 297
G
Sbjct: 307 G 307
>COLT_DROME (Q9VQG4) Congested-like trachea protein
Length = 306
Score = 187 bits (476), Expect = 2e-47
Identities = 112/289 (38%), Positives = 149/289 (50%), Gaps = 14/289 (4%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGL 65
K G FGG ++ GHP DTIKV+LQ+ P P PG+ P Y G D +T+ EG RGL
Sbjct: 17 KSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGL 76
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
YKGM APL VA + A+ F + L + A LT Q G+ +GL + ++ P
Sbjct: 77 YKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPG 136
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
E IK LQ Q G KY G +D A L EGG R +FKG TM R++P N
Sbjct: 137 ERIKVLLQTQQGQGGER------KYNGMIDCAGK-LYKEGGLRSVFKGSCATMLRDLPAN 189
Query: 186 AAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ---VDD 242
F YEA + + +T + S I AGG+AG ++W P DV+KS +Q
Sbjct: 190 GLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGT 249
Query: 243 YKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEM 291
YK+ G F+ ++ +G LY+G P M R+ PANAACF E+
Sbjct: 250 YKH----GIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIEL 294
Score = 64.7 bits (156), Expect = 3e-10
Identities = 52/196 (26%), Positives = 84/196 (42%), Gaps = 27/196 (13%)
Query: 10 AGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGLYKGM 69
AG+F G ++ P + IKV LQ+Q G +Y+G ID + G R ++KG
Sbjct: 121 AGSFSGLFSTLIMAPGERIKVLLQTQQGQ--GGERKYNGMIDCAGKLYKEGGLRSVFKGS 178
Query: 70 GAPLATVAALNAVLFTVRGQMEALFRSHPGAS-LTVHQQVFCGAGAGLAVSFLVCPTELI 128
A + N + F V ++ + +S ++ +F G AG+A L P +++
Sbjct: 179 CATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVL 238
Query: 129 KCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRS-------EGGARGLFKGLVPTMARE 181
K RLQ+ P +H +RS + G L++G+ P M R
Sbjct: 239 KSRLQS-----------------APEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRA 281
Query: 182 VPGNAAMFGAYEASKQ 197
P NAA F E + +
Sbjct: 282 FPANAACFFGIELANK 297
Score = 37.0 bits (84), Expect = 0.059
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 5 AKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAV-KQTLAAEGPR 63
A + AG G A I+G P D +K +LQS P Y I +V K + +GP
Sbjct: 215 ASTIFAGGVAGMAYWILGMPADVLKSRLQSAPE------GTYKHGIRSVFKDLIVKDGPL 268
Query: 64 GLYKGMGAPLATVAALNAVLF 84
LY+G+ + NA F
Sbjct: 269 ALYRGVTPIMLRAFPANAACF 289
>ORT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute
carrier family 25, member 15) (SP1855)
Length = 301
Score = 181 bits (460), Expect = 1e-45
Identities = 115/296 (38%), Positives = 151/296 (50%), Gaps = 15/296 (5%)
Query: 5 AKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRG 64
A DLTAG GG A ++ G PFDT+KVK+Q+ P Y G D +T + G RG
Sbjct: 10 AIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPD-------LYRGLTDCCLKTYSQVGFRG 62
Query: 65 LYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPG----ASLTVHQQVFCGAGAGLAVSF 120
YKG L A N+VLF G + + R G A L+ Q G+ A +
Sbjct: 63 FYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAAL 122
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
++CPTEL+KCRLQ + SG +A V + +LR +G G + GL T+ R
Sbjct: 123 VLCPTELVKCRLQTMYEMETSGK--IAKSQNTVWSVIKSILRKDGPL-GFYHGLSSTLLR 179
Query: 181 EVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQV 240
EVPG FG YE S+ A G LG L+++GG+ G W VYP D +KS IQV
Sbjct: 180 EVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQV 239
Query: 241 DDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
K +G I F ++ +EGI LY G P M R+ PAN A FLAYE +R +
Sbjct: 240 LSMS-GKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
>ORT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute
carrier family 25, member 15)
Length = 301
Score = 180 bits (457), Expect = 3e-45
Identities = 114/296 (38%), Positives = 149/296 (49%), Gaps = 15/296 (5%)
Query: 5 AKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRG 64
A DLTAG GG A ++ G PFDT+KVK+Q+ P Y G D +T + G RG
Sbjct: 10 AIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPD-------LYRGLTDCCLKTYSQVGFRG 62
Query: 65 LYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPG----ASLTVHQQVFCGAGAGLAVSF 120
YKG L A N+VLF G + + R G A L+ Q G+ A +
Sbjct: 63 FYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAAL 122
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
++CPTEL+KCRLQ + SG +A V + + R +G G + GL T+ R
Sbjct: 123 VLCPTELVKCRLQTMYEMETSGK--IAASQNTVWSVVKEIFRKDGPL-GFYHGLSSTLLR 179
Query: 181 EVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQV 240
EVPG FG YE S+ A G LG L+++GG G W VYP D +KS IQV
Sbjct: 180 EVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQV 239
Query: 241 DDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
K +G + F I+ +EGI LY G P M R+ PAN A FLAYE +R +
Sbjct: 240 LSMT-GKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
>ORT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute
carrier family 25, member 2)
Length = 301
Score = 180 bits (456), Expect = 4e-45
Identities = 113/296 (38%), Positives = 151/296 (50%), Gaps = 15/296 (5%)
Query: 5 AKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRG 64
A DLTAG GG A ++ G PFDTIKVK+Q+ P Y G D +T A G RG
Sbjct: 10 AIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPD-------LYKGLTDCFLKTYAQVGLRG 62
Query: 65 LYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPG----ASLTVHQQVFCGAGAGLAVSF 120
YKG G L A N+VLF G + R G A L+ Q G+ A +
Sbjct: 63 FYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAAL 122
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
+CPTEL+KCRLQ + SG +A + V + +L+ +G G + GL T+ +
Sbjct: 123 ALCPTELVKCRLQTMYEMEMSGK--IAKSHNTIWSVVKGILKKDGPL-GFYHGLSSTLLQ 179
Query: 181 EVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQV 240
E PG FG YE S+ A G LG L+++GG+AG W V+P D +KS IQV
Sbjct: 180 EGPGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLIVFPVDCIKSRIQV 239
Query: 241 DDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
Y K +G I ++ +EGI LY G M R++PAN A F+AYE +R +
Sbjct: 240 LS-MYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMM 294
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor
Length = 329
Score = 164 bits (414), Expect = 3e-40
Identities = 111/312 (35%), Positives = 153/312 (48%), Gaps = 36/312 (11%)
Query: 4 VAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPR 63
V KD+ AGT GG AQ++VG PFDT KV+LQ+ T + ++ ++ + EG
Sbjct: 34 VLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTR--------TTTLEVLRNLVKNEGVF 85
Query: 64 GLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGA----------------SLTVHQQ 107
YKG PL V +V F V M+ F+++ + +L + Q
Sbjct: 86 AFYKGALTPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQY 145
Query: 108 VFCGAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGA 167
CG G+ SFL P E I+ RLQ Q++ G ++ GP D + L+++GG
Sbjct: 146 YVCGLTGGVVNSFLASPIEQIRIRLQTQTSNGGDR------EFKGPWDCIKK-LKAQGG- 197
Query: 168 RGLFKGLVPTMAREVPGNAAMFGAYEASKQLLAG-GPDTSGLGRGSLIVAGGLAGASFWF 226
L +GL PTM R G F YEA G G + + L + G +G W
Sbjct: 198 --LMRGLFPTMIRAGHGLGTYFLVYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWL 255
Query: 227 FVYPTDVVKSVIQVDDYKYPKFSGSID-AFRRILASEGIKGLYKGFGPAMFRSVPANAAC 285
VYP DVVKS+IQ DD + PK+ SI + I A EGI+ +KGFGP M RS P N A
Sbjct: 256 TVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGAT 315
Query: 286 FLAYEMTRSALG 297
FL +E+ LG
Sbjct: 316 FLTFELVMRFLG 327
Score = 35.0 bits (79), Expect = 0.22
Identities = 49/207 (23%), Positives = 80/207 (37%), Gaps = 31/207 (14%)
Query: 100 ASLTVHQQVFCGAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARH 159
+S V + +F G G+A + P + K RLQ +T + ++V R+
Sbjct: 30 SSNRVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTRTTT------------LEVLRN 77
Query: 160 VLRSEG------GARGLFKGLVPTMAREVPGNAAM---FGAYEASKQLLAGGPD-----T 205
++++EG GA G+ ++ + N AM F Y ASK D +
Sbjct: 78 LVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRS 137
Query: 206 SGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQVDDYK--YPKFSGSIDAFRRILASEG 263
+ L V G G F P + ++ +Q +F G D +++ A
Sbjct: 138 NTLPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQTQTSNGGDREFKGPWDCIKKLKAQ-- 195
Query: 264 IKGLYKGFGPAMFRSVPANAACFLAYE 290
GL +G P M R+ FL YE
Sbjct: 196 -GGLMRGLFPTMIRAGHGLGTYFLVYE 221
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c
Length = 302
Score = 158 bits (400), Expect = 1e-38
Identities = 110/292 (37%), Positives = 142/292 (47%), Gaps = 24/292 (8%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGL 65
KD AG GG AQ++VG PFD +KV+LQSQ P Y+ A+D VK+ EG
Sbjct: 19 KDFLAGVSGGVAQVLVGQPFDCVKVRLQSQ----SNVSPIYNNALDCVKKISKNEGLAAF 74
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
YKG PL + ++ FT + F S G +T+ Q GA +GLA SFLV P
Sbjct: 75 YKGTVLPLLGIGFCVSIQFTTFEYCKRFF-SRDGTPVTMPQYYVSGAISGLANSFLVGPV 133
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
E ++ RLQ Q+ V Y GP D + + S+ G G+ KG PT ARE G
Sbjct: 134 EHVRIRLQIQT--------GKNVLYHGPWDCIKKI-SSQYGLSGIMKGYNPTAAREAHGL 184
Query: 186 AAMFGAYEA------SKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQ 239
F AYEA +K L T G L V G AG + W YP D+VKS IQ
Sbjct: 185 GMYFLAYEALVKNTMAKHHLTDRSQTPG---WKLCVFGAGAGYAMWLAAYPFDIVKSKIQ 241
Query: 240 VDDY-KYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYE 290
D + + S + I G++G Y+GF P + R+ PANA F YE
Sbjct: 242 TDGFLSKATYKNSWQCAKGIYTKAGLRGFYRGFVPVLVRAAPANAVTFYVYE 293
Score = 60.8 bits (146), Expect = 4e-09
Identities = 52/197 (26%), Positives = 82/197 (41%), Gaps = 26/197 (13%)
Query: 10 AGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGLYKGM 69
+G G A + P + ++++LQ Q G+ Y G D +K+ + G G+ KG
Sbjct: 118 SGAISGLANSFLVGPVEHVRIRLQIQT----GKNVLYHGPWDCIKKISSQYGLSGIMKGY 173
Query: 70 GAPLATVA--------ALNAVLFTVRGQMEALFRSH-PGASLTVHQQVFCGAGAGLAVSF 120
A A A A++ + RS PG L V GAGAG A+
Sbjct: 174 NPTAAREAHGLGMYFLAYEALVKNTMAKHHLTDRSQTPGWKLCVF-----GAGAGYAMWL 228
Query: 121 LVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAR 180
P +++K ++Q L+ + Y A+ + ++ G RG ++G VP + R
Sbjct: 229 AAYPFDIVKSKIQTDGFLSKA-------TYKNSWQCAKGIY-TKAGLRGFYRGFVPVLVR 280
Query: 181 EVPGNAAMFGAYEASKQ 197
P NA F YE Q
Sbjct: 281 AAPANAVTFYVYETVSQ 297
>CACL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier
protein CACL (CACT-like)
Length = 306
Score = 157 bits (396), Expect = 4e-38
Identities = 101/285 (35%), Positives = 145/285 (50%), Gaps = 21/285 (7%)
Query: 4 VAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPR 63
+A D AG GG A +IVGHPFD +KV+LQ Q T + P+Y G + + + E
Sbjct: 1 MALDFLAGCAGGVAGVIVGHPFDIVKVRLQVQST----EKPQYRGTLHCFQSIIKQESVL 56
Query: 64 GLYKGMGAPLATVAALNAVLFTVRGQ-MEALFRSHPGASLTVHQQVFCGAGAGLAVSFLV 122
GLYKG+G+PL + +NA++F V+G + AL + P Q GA AG +
Sbjct: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSP------LNQFLAGAAAGAIQCVIC 110
Query: 123 CPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREV 182
CP EL K RLQ Q+ A Y G +D + R E G RG+ +G+V T+ RE
Sbjct: 111 CPMELAKTRLQLQA-------VGPARTYKGSLDCLVQIYRHE-GLRGINRGMVSTLLRET 162
Query: 183 PGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQVDD 242
P F Y+ + + P L L++AGG +G + W YP DVVKS +Q D
Sbjct: 163 PSFGVYFLTYDVMTRAMGCEPG-DRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADG 221
Query: 243 YK-YPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACF 286
+ P++ G +D R+ +EG + +G + R+ P NAA F
Sbjct: 222 LQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATF 266
Score = 60.1 bits (144), Expect = 7e-09
Identities = 50/191 (26%), Positives = 85/191 (44%), Gaps = 22/191 (11%)
Query: 111 GAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGL 170
G G+A + P +++K RLQ QST +Y G + + +++ E GL
Sbjct: 8 GCAGGVAGVIVGHPFDIVKVRLQVQST--------EKPQYRGTLHCFQSIIKQES-VLGL 58
Query: 171 FKGLVPTMAREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLI---VAGGLAGASFWFF 227
+KGL + NA +FG G LG+ S + +AG AGA
Sbjct: 59 YKGLGSPLMGLTFINALVFGVQ---------GNTLRALGQDSPLNQFLAGAAAGAIQCVI 109
Query: 228 VYPTDVVKSVIQVDDYKYPK-FSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACF 286
P ++ K+ +Q+ + + GS+D +I EG++G+ +G + R P+ F
Sbjct: 110 CCPMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYF 169
Query: 287 LAYEMTRSALG 297
L Y++ A+G
Sbjct: 170 LTYDVMTRAMG 180
>CACL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier
protein CACL (CACT-like)
Length = 303
Score = 155 bits (393), Expect = 9e-38
Identities = 102/285 (35%), Positives = 142/285 (49%), Gaps = 21/285 (7%)
Query: 4 VAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPR 63
+A D AG GG A ++VGHPFDT+KV+LQ Q + P+Y G + K + E
Sbjct: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSV----EKPQYRGTLHCFKSIIKQESVL 56
Query: 64 GLYKGMGAPLATVAALNAVLFTVRGQ-MEALFRSHPGASLTVHQQVFCGAGAGLAVSFLV 122
GLYKG+G+PL + +NA++F V+G + AL P Q GA AG +
Sbjct: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSP------LNQFLAGAAAGAIQCVIC 110
Query: 123 CPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREV 182
CP EL K RLQ Q A A Y G +D + E G RG+ +G+V T+ RE
Sbjct: 111 CPMELAKTRLQLQD-------AGPARTYKGSLDCLAQIYGHE-GLRGVNRGMVSTLLRET 162
Query: 183 PGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQVDD 242
P F Y+A + L P L L++AGG +G W YP DVVKS +Q D
Sbjct: 163 PSFGVYFLTYDALTRALGCEPG-DRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADG 221
Query: 243 YK-YPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACF 286
+ P++ G +D + +EG + +G + R+ P NAA F
Sbjct: 222 LRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
Score = 60.5 bits (145), Expect = 5e-09
Identities = 51/191 (26%), Positives = 82/191 (42%), Gaps = 22/191 (11%)
Query: 111 GAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGL 170
G G+A + P + +K RLQ QS +Y G + + +++ E GL
Sbjct: 8 GCAGGVAGVLVGHPFDTVKVRLQVQSV--------EKPQYRGTLHCFKSIIKQES-VLGL 58
Query: 171 FKGLVPTMAREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLI---VAGGLAGASFWFF 227
+KGL + NA +FG G LG S + +AG AGA
Sbjct: 59 YKGLGSPLMGLTFINALVFGVQ---------GNTLRALGHDSPLNQFLAGAAAGAIQCVI 109
Query: 228 VYPTDVVKSVIQVDDYKYPK-FSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACF 286
P ++ K+ +Q+ D + + GS+D +I EG++G+ +G + R P+ F
Sbjct: 110 CCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYF 169
Query: 287 LAYEMTRSALG 297
L Y+ ALG
Sbjct: 170 LTYDALTRALG 180
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier
Length = 327
Score = 142 bits (358), Expect = 1e-33
Identities = 101/301 (33%), Positives = 142/301 (46%), Gaps = 29/301 (9%)
Query: 6 KDLTAGTFGGAAQLIVGHPFDTIKVKLQSQP--TPIPGQLPRYSGAIDAVKQTLAAEGPR 63
K AG GG + GHPFD IKV+ Q+ + + A VK TL +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 64 GLYKGMGAPLATVAALNAVLFTVR--GQMEALFRSHPGAS--LTVHQQVFCGAGAGLAVS 119
G YKG+ PL V + AV F G+ F + G S LT+ Q G + + +
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPTT 156
Query: 120 FLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMA 179
+ PTE +K LQ S G + A+ +++ EGG LFKG + T+A
Sbjct: 157 LVTAPTERVKVVLQTSSK-------------GSFIQAAKTIVK-EGGIASLFKGSLATLA 202
Query: 180 REVPGNAAMFGAYEASKQLLAGGPDTSGLGRG------SLIVAGGLAGASFWFFVYPTDV 233
R+ PG+A F +YE SK L G+ ++ +AGG+AG S W V+P D
Sbjct: 203 RDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDT 262
Query: 234 VKSVIQVDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTR 293
+K+ +Q + S + + + L GIKG + G GPA+ RS PANAA FL EMT
Sbjct: 263 IKTKLQASSTRQNMLSATKEIY---LQRGGIKGFFPGLGPALLRSFPANAATFLGVEMTH 319
Query: 294 S 294
S
Sbjct: 320 S 320
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/190 (26%), Positives = 80/190 (41%), Gaps = 13/190 (6%)
Query: 111 GAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGL 170
G G+ F P +LIK R Q+ A S A+ + L + +G
Sbjct: 42 GGVGGVCAVFTGHPFDLIKVR--CQNGQANSTVHAITNIIKEAKTQVKGTLFTNS-VKGF 98
Query: 171 FKGLVPTMAREVPGNAAMFGAYEASKQLLAGGPDTSG---LGRGSLIVAGGLAGASFWFF 227
+KG++P + P A F Y+ K+L+ G L G + AG ++
Sbjct: 99 YKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPTTLV 158
Query: 228 VYPTDVVKSVIQVDDYKYPKFSGS-IDAFRRILASEGIKGLYKGFGPAMFRSVPANAACF 286
PT+ VK V+Q GS I A + I+ GI L+KG + R P +A F
Sbjct: 159 TAPTERVKVVLQTSS------KGSFIQAAKTIVKEGGIASLFKGSLATLARDGPGSALYF 212
Query: 287 LAYEMTRSAL 296
+YE++++ L
Sbjct: 213 ASYEISKNYL 222
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/205 (26%), Positives = 77/205 (36%), Gaps = 31/205 (15%)
Query: 1 MGDVAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAE 60
MG +A AG +V P + +KV LQ+ I A K +
Sbjct: 141 MGQMA---AAGFISAIPTTLVTAPTERVKVVLQTSSK---------GSFIQAAKTIVKEG 188
Query: 61 GPRGLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHP-----GASLTVHQQVFCGAG-- 113
G L+KG A LA +A+ F + S G V+ C AG
Sbjct: 189 GIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGI 248
Query: 114 AGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKG 173
AG+++ V P + IK +LQA ST + + + GG +G F G
Sbjct: 249 AGMSMWLAVFPIDTIKTKLQASSTRQNM------------LSATKEIYLQRGGIKGFFPG 296
Query: 174 LVPTMAREVPGNAAMFGAYEASKQL 198
L P + R P NAA F E + L
Sbjct: 297 LGPALLRSFPANAATFLGVEMTHSL 321
Score = 33.5 bits (75), Expect = 0.65
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 9/89 (10%)
Query: 10 AGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQT-LAAEGPRGLYKG 68
AG G + + P DTIK KLQ+ T + A K+ L G +G + G
Sbjct: 245 AGGIAGMSMWLAVFPIDTIKTKLQASSTR--------QNMLSATKEIYLQRGGIKGFFPG 296
Query: 69 MGAPLATVAALNAVLFTVRGQMEALFRSH 97
+G L NA F +LF+ +
Sbjct: 297 LGPALLRSFPANAATFLGVEMTHSLFKKY 325
>AR13_NEUCR (Q01356) Amino acid transporter arg-13
Length = 363
Score = 141 bits (356), Expect = 2e-33
Identities = 101/322 (31%), Positives = 154/322 (47%), Gaps = 42/322 (13%)
Query: 3 DVAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGP 62
+ +D+ G+ G + +PFDT+KV+LQSQP +P RY+G +D +Q++ A+G
Sbjct: 41 EALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLP---LRYTGPLDCFRQSIRADGF 97
Query: 63 RGLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGA----SLTVHQQVFCGAGAGLAV 118
GLY+G+ APL A N+ LF +L S A L++ F G +G
Sbjct: 98 LGLYRGISAPLVGAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSALWFTGGFSGAFT 157
Query: 119 SFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTM 178
S ++ P EL+KC++Q G+G +K P+ V + + R E G RG + G + T+
Sbjct: 158 SLILTPVELVKCKIQVPDEPGGAGARQRQLK---PIPVIKEIFRHE-GLRGFWHGQLGTL 213
Query: 179 AREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGS-----------------LIVAGGLAG 221
RE G AA FG+ E + + G + + L RG+ +AG AG
Sbjct: 214 IREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAGASAG 273
Query: 222 ASFWFFVYPTDVVKSVIQVDDY-------------KYPKFSGSIDAFRRILASEGIKGLY 268
S+ F +P D VKS +Q PK S +A R + GIKG Y
Sbjct: 274 MSYNFLFFPADTVKSRMQTSPIGGGGDNGGKGAATMMPKKSFGEEA-RALWKQAGIKGFY 332
Query: 269 KGFGPAMFRSVPANAACFLAYE 290
+G G + RS P++A F+ Y+
Sbjct: 333 RGCGITVLRSAPSSAFIFMVYD 354
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/84 (30%), Positives = 42/84 (49%), Gaps = 1/84 (1%)
Query: 214 IVAGGLAGASFWFFVYPTDVVKSVIQVDDYKYP-KFSGSIDAFRRILASEGIKGLYKGFG 272
IV G AG + YP D VK +Q P +++G +D FR+ + ++G GLY+G
Sbjct: 46 IVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADGFLGLYRGIS 105
Query: 273 PAMFRSVPANAACFLAYEMTRSAL 296
+ + N++ F + RS L
Sbjct: 106 APLVGAALENSSLFFFERIGRSLL 129
Score = 30.4 bits (67), Expect = 5.5
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 8/93 (8%)
Query: 10 AGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAE--------G 61
AG G + + P DT+K ++Q+ P G A K++ E G
Sbjct: 268 AGASAGMSYNFLFFPADTVKSRMQTSPIGGGGDNGGKGAATMMPKKSFGEEARALWKQAG 327
Query: 62 PRGLYKGMGAPLATVAALNAVLFTVRGQMEALF 94
+G Y+G G + A +A +F V ++ F
Sbjct: 328 IKGFYRGCGITVLRSAPSSAFIFMVYDGLKKYF 360
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein
Length = 292
Score = 133 bits (334), Expect = 6e-31
Identities = 94/296 (31%), Positives = 142/296 (47%), Gaps = 25/296 (8%)
Query: 7 DLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEG-PRGL 65
D+ G+ GA ++ PFDT+KV+LQ+Q + + + +K T EG RG
Sbjct: 16 DIINGSIAGACGKVIEFPFDTVKVRLQTQASNV------FPTTWSCIKFTYQNEGIARGF 69
Query: 66 YKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPT 125
++G+ +PL NA LF Q H + Q + G AG S ++ P
Sbjct: 70 FQGIASPLVGACLENATLFVSYNQCSKFLEKHTNV-FPLGQILISGGVAGSCASLVLTPV 128
Query: 126 ELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGN 185
EL+KC+LQ +A A+ K+ + + ++ +E G GL++G T RE G
Sbjct: 129 ELVKCKLQ----VANLQVASAKTKHTKVLPTIKAII-TERGLAGLWQGQSGTFIRESFGG 183
Query: 186 AAMFGAYEASKQLLAGGPDTSGLGRGS-----LIVAGGLAGASFWFFVYPTDVVKSVIQV 240
A F YE K+ L R L+++GG AG +F ++P D VKSV+Q
Sbjct: 184 VAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQT 243
Query: 241 DDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEMTRSAL 296
+ +A ++I G+KG Y+G G +FR+VPANAA F +E T SAL
Sbjct: 244 EHISLT------NAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFE-TLSAL 292
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1
Length = 310
Score = 122 bits (305), Expect = 1e-27
Identities = 84/292 (28%), Positives = 135/292 (45%), Gaps = 24/292 (8%)
Query: 9 TAGTFGGAAQLIVGHPFDTIKVKLQSQPTP--------IPGQLPRYSGAIDAVKQTLAAE 60
TAG G ++L+V +P D +K ++Q Q T + Y+G +D + + + E
Sbjct: 16 TAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKE 75
Query: 61 GPRGLYKGMGAPLATVAALNAVLFTVRGQMEALFRS---HPGASLTVHQQVFCGAGAGLA 117
G LYKG+ +P+ A A+ F+ + ++ P +T ++ GA AG
Sbjct: 76 GFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGAV 135
Query: 118 VSFLVCPTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPT 177
+F+V P EL+K RLQ ++ ++ P++V ++ + +GG LF GL T
Sbjct: 136 EAFVVAPFELVKIRLQDVNS-----------QFKTPIEVVKNSV-VKGGVLSLFNGLEAT 183
Query: 178 MAREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSV 237
+ R V NA FG ++LL ++ R LI AG + G P DVVKS
Sbjct: 184 IWRHVLWNAGYFGIIFQIRKLLPAAKTSTEKTRNDLI-AGAIGGTVGCLLNTPFDVVKSR 242
Query: 238 IQVDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAY 289
IQ K++ S+ + + EG K LYKGF P + R P + +
Sbjct: 243 IQRSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLAPGGGLLLVVF 294
Score = 57.4 bits (137), Expect = 4e-08
Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 12/187 (6%)
Query: 107 QVFCGAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAVK-----YGGPMDVARHVL 161
Q GA AG++ ++ P +++K R+Q Q T G A VA K Y G MD ++
Sbjct: 14 QFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGH-PAVVAAKAAVDHYTGVMDCLTKIV 72
Query: 162 RSEGGARGLFKGLVPTMAREVPGNAAMFGAYEASKQLLAG-GPDTSG-LGRGSLIVAGGL 219
+ EG + L+KG+ + E P A F + + P +G + + I +G
Sbjct: 73 KKEGFSH-LYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGAS 131
Query: 220 AGASFWFFVYPTDVVKSVIQVDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSV 279
AGA F V P ++VK I++ D +F I+ + + G+ L+ G ++R V
Sbjct: 132 AGAVEAFVVAPFELVK--IRLQDVN-SQFKTPIEVVKNSVVKGGVLSLFNGLEATIWRHV 188
Query: 280 PANAACF 286
NA F
Sbjct: 189 LWNAGYF 195
Score = 43.5 bits (101), Expect = 6e-04
Identities = 26/89 (29%), Positives = 41/89 (45%), Gaps = 4/89 (4%)
Query: 7 DLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGLY 66
DL AG GG ++ PFD +K ++Q G L +Y+ ++ +V EG + LY
Sbjct: 218 DLIAGAIGGTVGCLLNTPFDVVKSRIQRS----SGPLRKYNWSLPSVLLVYREEGFKALY 273
Query: 67 KGMGAPLATVAALNAVLFTVRGQMEALFR 95
KG + +A +L V + FR
Sbjct: 274 KGFAPKVMRLAPGGGLLLVVFTNVMDFFR 302
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein
Aralar2 (Mitochondrial aspartate glutamate carrier 2)
(Solute carrier family 25, member 13) (Citrin)
Length = 675
Score = 117 bits (293), Expect = 3e-26
Identities = 93/284 (32%), Positives = 135/284 (46%), Gaps = 19/284 (6%)
Query: 11 GTFGGAAQLIVGHPFDTIKVKLQSQPTP--IPGQLPRYSGAIDAVKQTLAAEGPRGLYKG 68
G+ GA +P D +K ++Q+Q + G+L Y + D K+ L EG GLY+G
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGEL-MYKNSFDCFKKVLRYEGFFGLYRG 393
Query: 69 MGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPTELI 128
+ L VA A+ TV + F H S+ + ++ G AG + P E++
Sbjct: 394 LLPQLLGVAPEKAIKLTVNDFVRDKFM-HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIV 452
Query: 129 KCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGNAAM 188
K RLQ +AG T GP A V+R + G G++KG R++P +A
Sbjct: 453 KIRLQ----VAGEITT-------GPRVSALSVVR-DLGFFGIYKGAKACFLRDIPFSAIY 500
Query: 189 FGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQVDDYK-YPK 247
F Y K A + + GSL++AG +AG V P DV+K+ +QV
Sbjct: 501 FPCYAHVKASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT 558
Query: 248 FSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAYEM 291
+SG ID FR+IL EG K L+KG G +FRS P L YE+
Sbjct: 559 YSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 602
Score = 63.9 bits (154), Expect = 5e-10
Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 16/190 (8%)
Query: 4 VAKDLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPR 63
+A ++ AG G +Q+I +P + +K++LQ G PR S A+ V+ G
Sbjct: 428 LAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG--PRVS-ALSVVRDL----GFF 480
Query: 64 GLYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVC 123
G+YKG A +A+ F ++A F + G ++ + GA AG+ + LV
Sbjct: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG-QVSPGSLLLAGAIAGMPAASLVT 539
Query: 124 PTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVP 183
P ++IK RLQ + AG T Y G +D R +LR E G + L+KG + R P
Sbjct: 540 PADVIKTRLQV-AARAGQTT------YSGVIDCFRKILREE-GPKALWKGAGARVFRSSP 591
Query: 184 GNAAMFGAYE 193
YE
Sbjct: 592 QFGVTLLTYE 601
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2
Length = 307
Score = 115 bits (289), Expect = 1e-25
Identities = 84/290 (28%), Positives = 134/290 (45%), Gaps = 24/290 (8%)
Query: 10 AGTFGGAAQLIVGHPFDTIKVKLQSQPTP-----IPGQLPRYSGAIDAVKQTLAAEGPRG 64
+G G ++L V +P D +K + Q + T + Q+ RY+G ID +K+ + EG
Sbjct: 18 SGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGFSR 77
Query: 65 LYKGMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQ-QVFCGAGAGLAVSFLVC 123
LY+G+ +P+ A A F Q + +F++ + T + + GA AG+ + ++
Sbjct: 78 LYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAGASAGMTEAAVIV 137
Query: 124 PTELIKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVP 183
P ELIK R+Q V Y GPMD + +++E G GL+KG+ TM R
Sbjct: 138 PFELIKIRMQ-----------DVKSSYLGPMDCLKKTIKNE-GIMGLYKGIESTMWRNAL 185
Query: 184 GNAAMFGA-YEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFWFFVYPTDVVKSVIQVDD 242
N FG Y+ + T G + ++AG + G P DVVKS IQ D
Sbjct: 186 WNGGYFGVIYQVRNSMPVA--KTKGQKTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVD 243
Query: 243 ---YKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAACFLAY 289
K++ + + I EG + LYKGF P + R P + + +
Sbjct: 244 AVSSAVKKYNWCLPSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVF 293
Score = 73.9 bits (180), Expect = 4e-13
Identities = 50/191 (26%), Positives = 94/191 (49%), Gaps = 5/191 (2%)
Query: 107 QVFCGAGAGLAVSFLVCPTELIKCRLQAQSTLAGSGTAAVAV-KYGGPMDVARHVLRSEG 165
Q GA AG++ ++ P +++K R Q + T + V +Y G +D + +++ EG
Sbjct: 15 QFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEG 74
Query: 166 GARGLFKGLVPTMAREVPGNAAMFGAYEASKQLLAGGPDTSGLGRGSLIVAGGLAGASFW 225
+R L++G+ M E P A F + +++ +T+ + I AG AG +
Sbjct: 75 FSR-LYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAGASAGMTEA 133
Query: 226 FFVYPTDVVKSVIQVDDYKYPKFSGSIDAFRRILASEGIKGLYKGFGPAMFRSVPANAAC 285
+ P +++K I++ D K + G +D ++ + +EGI GLYKG M+R+ N
Sbjct: 134 AVIVPFELIK--IRMQDVK-SSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGY 190
Query: 286 FLAYEMTRSAL 296
F R+++
Sbjct: 191 FGVIYQVRNSM 201
Score = 64.7 bits (156), Expect = 3e-10
Identities = 49/181 (27%), Positives = 79/181 (43%), Gaps = 13/181 (7%)
Query: 8 LTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGLYK 67
+ AG G + V PF+ IK+++Q + Y G +D +K+T+ EG GLYK
Sbjct: 122 IAAGASAGMTEAAVIVPFELIKIRMQDVKS-------SYLGPMDCLKKTIKNEGIMGLYK 174
Query: 68 GMGAPLATVAALNAVLFTVRGQMEALFRSHPGASLTVHQQVFCGAGAGLAVSFLVCPTEL 127
G+ + + A N F V Q+ + GA G + L P ++
Sbjct: 175 GIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTRNDLIAGAIGGTVGTMLNTPFDV 234
Query: 128 IKCRLQAQSTLAGSGTAAVAVKYGGPMDVARHVLRSEGGARGLFKGLVPTMAREVPGNAA 187
+K R+Q+ + ++ KY + + R E G R L+KG VP + R PG +
Sbjct: 235 VKSRIQSVDAV-----SSAVKKYNWCLPSLLVIYREE-GFRALYKGFVPKVCRLAPGGSL 288
Query: 188 M 188
M
Sbjct: 289 M 289
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 7 DLTAGTFGGAAQLIVGHPFDTIKVKLQSQPTPIPGQLPRYSGAIDAVKQTLAAEGPRGLY 66
DL AG GG ++ PFD +K ++QS + + +Y+ + ++ EG R LY
Sbjct: 214 DLIAGAIGGTVGTMLNTPFDVVKSRIQSVDA-VSSAVKKYNWCLPSLLVIYREEGFRALY 272
Query: 67 KGMGAPLATVAALNAVLFTVRGQMEALFR 95
KG + +A +++ V M FR
Sbjct: 273 KGFVPKVCRLAPGGSLMLVVFTGMMNFFR 301
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.138 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,055,793
Number of Sequences: 164201
Number of extensions: 1534512
Number of successful extensions: 4678
Number of sequences better than 10.0: 150
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3307
Number of HSP's gapped (non-prelim): 390
length of query: 297
length of database: 59,974,054
effective HSP length: 109
effective length of query: 188
effective length of database: 42,076,145
effective search space: 7910315260
effective search space used: 7910315260
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Lotus: description of TM0381.7