BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0381.3
         (253 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

LIN1_NYCCO (P08548) LINE-1 reverse transcriptase homolog               90  6e-18
POL2_MOUSE (P11369) Retrovirus-related Pol polyprotein [Contains...    86  7e-17
LIN1_HUMAN (P08547) LINE-1 reverse transcriptase homolog               77  3e-14
POLR_DROME (P16423) Retrovirus-related Pol polyprotein from type...    74  3e-13
YTX2_XENLA (P14381) Transposon TX1 hypothetical 149 kDa protein ...    68  2e-11
MC50_ARATH (P92555) Hypothetical mitochondrial protein AtMg01250...    62  2e-09
PO23_POPJA (Q05118) Retrovirus-related Pol polyprotein from type...    55  2e-07
PO21_NASVI (Q03278) Retrovirus-related Pol polyprotein from type...    49  9e-06
PO22_POPJA (Q03274) Retrovirus-related Pol polyprotein from type...    49  1e-05
PO21_SCICO (Q03279) Retrovirus-related Pol polyprotein from type...    44  5e-04
RT16_MYXXA (P23072) RNA-directed DNA polymerase from retron Mx16...    34  0.39
HEM1_OCEIH (Q8EPM7) Glutamyl-tRNA reductase (EC 1.2.1.-) (GluTR)       33  0.50
CH62_CHLCV (P59698) 60 kDa chaperonin 2 (Protein Cpn60 2) (groEL...    33  0.86
MTB5_NEIGO (Q59605) Modification methylase NgoBV (EC 2.1.1.37) (...    32  1.9
PO12_NASVI (Q03270) Retrovirus-related Pol polyprotein from type...    30  4.3
IRA2_YEAST (P19158) Inhibitory regulator protein IRA2                  30  4.3
Y2R2_DROME (P16425) Hypothetical 115 kDa protein in type I retro...    30  5.6
ARH1_HUMAN (Q92888) Rho guanine nucleotide exchange factor 1 (p1...    30  7.3
YMH5_CAEEL (P34472) Hypothetical protein F58A4.5 in chromosome III     29  9.5
VG12_BPPZA (P07537) Pre-neck appendage protein (Late protein GP12)     29  9.5

>LIN1_NYCCO (P08548) LINE-1 reverse transcriptase homolog
          Length = 1260

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 66/231 (28%), Positives = 114/231 (48%), Gaps = 8/231 (3%)

Query: 23  KGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMWGVKCPKLSILWNCSKLP 82
           K +  + + ID EKA+D +   F+  TL   G     + LI      P  +I+ N  KL 
Sbjct: 589 KNKDHMILSIDAEKAFDNIQHPFMIRTLKKIGIEGTFLKLIEAIYSKPTANIILNGVKLK 648

Query: 83  SFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDV 142
           SF  + G RQG PLSP LF + ME LAI I+    +   K + I  + + +S   FADD+
Sbjct: 649 SFPLRSGTRQGCPLSPLLFNIVMEVLAIAIRE---EKAIKGIHIGSEEIKLS--LFADDM 703

Query: 143 LLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAVDHRRQINLSHIAGISRAS 202
           +++ + +++    +   +KE+   SG K+N  KS + F    +++ +  +      +   
Sbjct: 704 IVYLENTRDSTTKLLEVIKEYSNVSGYKINTHKS-VAFIYTNNNQAEKTVKDSIPFTVVP 762

Query: 203 DLGKYLGIPLLKG--RVTKAHFASLIGKMSSRLTSWKNNLLNRAGRVCLAK 251
              KYLG+ L K    + K ++ +L  +++  +  WKN   +  GR+ + K
Sbjct: 763 KKMKYLGVYLTKDVKDLYKENYETLRKEIAEDVNKWKNIPCSWLGRINIVK 813


>POL2_MOUSE (P11369) Retrovirus-related Pol polyprotein [Contains:
           Reverse transcriptase (EC 2.7.7.49); Endonuclease]
          Length = 1300

 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 74/247 (29%), Positives = 120/247 (47%), Gaps = 9/247 (3%)

Query: 7   NIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMWG 66
           NI  +  V+H I+  K    ++ I +D EKA+D++   F+   L   G     +++I   
Sbjct: 601 NIRKSINVIHYINKLKDKNHMI-ISLDAEKAFDKIQHPFMIKVLERSGIQGPYLNMIKAI 659

Query: 67  VKCPKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRI 126
              P  +I  N  KL +   + G RQG PLSPYLF + +E LA  I+    Q   K ++I
Sbjct: 660 YSKPVANIKVNGEKLEAIPLKSGTRQGCPLSPYLFNIVLEVLARAIRQ---QKEIKGIQI 716

Query: 127 TKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAVDH 186
            K+ V IS L  ADD++++    K   + + N +  F E  G K+N +KS M F    + 
Sbjct: 717 GKEEVKISLL--ADDMIVYISDPKNSTRELLNLINSFGEVVGYKINSNKS-MAFLYTKNK 773

Query: 187 RRQINLSHIAGISRASDLGKYLGIPLLK--GRVTKAHFASLIGKMSSRLTSWKNNLLNRA 244
           + +  +      S  ++  KYLG+ L K    +   +F SL  ++   L  WK+   +  
Sbjct: 774 QAEKEIRETTPFSIVTNNIKYLGVTLTKEVKDLYDKNFKSLKKEIKEDLRRWKDLPCSWI 833

Query: 245 GRVCLAK 251
           GR+ + K
Sbjct: 834 GRINIVK 840


>LIN1_HUMAN (P08547) LINE-1 reverse transcriptase homolog
          Length = 1259

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 67/249 (26%), Positives = 116/249 (45%), Gaps = 13/249 (5%)

Query: 5   RDNIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIM 64
           R +I + Q +  T  T       + I ID EKA+D++   F+   L   G     + +I 
Sbjct: 576 RKSINIIQHINRTKDTNH-----MIISIDAEKAFDKIQQPFMLKPLNKLGIDGTYLKIIR 630

Query: 65  WGVKCPKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPV 124
                P  +I+ N  KL +   + G RQG PLSP L  + +E LA  I+    +   K +
Sbjct: 631 AIYDKPTANIILNGQKLEAPPLKTGTRQGCPLSPLLPNIVLEVLARAIRQ---EKEIKGI 687

Query: 125 RITKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAV 184
           ++ K+ V +S   FADD++++ +      Q +   +  F + SG K+N+ KS+  F    
Sbjct: 688 QLGKEEVKLS--LFADDMIVYLENPIVSAQNLLKLISNFSKVSGYKINVQKSQ-AFLYTN 744

Query: 185 DHRRQINLSHIAGISRASDLGKYLGIPLLKG--RVTKAHFASLIGKMSSRLTSWKNNLLN 242
           + + +  +      + AS   KYLGI L +    + K ++  L+ ++      WKN   +
Sbjct: 745 NRQTESQIMSELPFTIASKRIKYLGIQLTRDVKDLFKENYKPLLNEIKEDTNKWKNIPCS 804

Query: 243 RAGRVCLAK 251
             GR+ + K
Sbjct: 805 WVGRINIVK 813


>POLR_DROME (P16423) Retrovirus-related Pol polyprotein from type II
           retrotransposable element R2DM [Contains: Protease (EC
           3.4.23.-); Reverse transcriptase (EC 2.7.7.49);
           Endonuclease]
          Length = 1057

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 69/239 (28%), Positives = 106/239 (43%), Gaps = 23/239 (9%)

Query: 6   DNIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMW 65
           DN  +   V+   H+ K  R      +D+ KA+D +S   +  TL  +G P   VD +  
Sbjct: 457 DNATIVDLVLR--HSHKHFRSCYIANLDVSKAFDSLSHASIYDTLRAYGAPKGFVDYVQN 514

Query: 66  GVKCPKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVR 125
             +    S+  +      F P RG++QGDPLSP LF L M+RL   + + +         
Sbjct: 515 TYEGGGTSLNGDGWSSEEFVPARGVKQGDPLSPILFNLVMDRLLRTLPSEIG-------- 566

Query: 126 ITKDGVGISH-LFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAV 184
             K G  I++   FADD++LF +       L++ TL +F    G+K+N DK   +  K  
Sbjct: 567 -AKVGNAITNAAAFADDLVLFAETRMGLQVLLDKTL-DFLSIVGLKLNADKCFTVGIKGQ 624

Query: 185 DHRR---------QINLSHIAGISRASDLGKYLGIPLLKGRVTKAHFASLIGKMSSRLT 234
             ++          +  S I  + R +D  KYLGI        + + A  IG    RLT
Sbjct: 625 PKQKCTVLEAQSFYVGSSEIPSLKR-TDEWKYLGINFTATGRVRCNPAEDIGPKLQRLT 682


>YTX2_XENLA (P14381) Transposon TX1 hypothetical 149 kDa protein
           (ORF 2)
          Length = 1308

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 64/244 (26%), Positives = 109/244 (44%), Gaps = 13/244 (5%)

Query: 6   DNIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMW 65
           DN+ L ++++H    ++ G  L  + +D EKA+DRV   +L  TL  + F P+ V  +  
Sbjct: 569 DNVFLIRDLLH--FARRTGLSLAFLSLDQEKAFDRVDHQYLIGTLQAYSFGPQFVGYLKT 626

Query: 66  GVKCPKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVR 125
                +  +  N S     A  RG+RQG PLS  L+ L +E     ++  +T      + 
Sbjct: 627 MYASAECLVKINWSLTAPLAFGRGVRQGCPLSGQLYSLAIEPFLCLLRKRLT-----GLV 681

Query: 126 ITKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAVD 185
           + +  + +    +ADDV+L  Q     L+      + +  AS  ++N  KS  L   ++ 
Sbjct: 682 LKEPDMRVVLSAYADDVILVAQ-DLVDLERAQECQEVYAAASSARINWSKSSGLLEGSL- 739

Query: 186 HRRQINLSHIAGISRASDLGKYLGIPL-LKGRVTKAHFASLIGKMSSRLTSWKN--NLLN 242
            +          IS  S + KYLG+ L  +      +F  L   + +RL  WK    +L+
Sbjct: 740 -KVDFLPPAFRDISWESKIIKYLGVYLSAEEYPVSQNFIELEECVLTRLGKWKGFAKVLS 798

Query: 243 RAGR 246
             GR
Sbjct: 799 MRGR 802


>MC50_ARATH (P92555) Hypothetical mitochondrial protein AtMg01250
           (ORF102)
          Length = 122

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 29/56 (51%), Positives = 37/56 (65%)

Query: 86  PQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADD 141
           P RGLRQGDPLSPYLF+LC E L+   +    QG    +R++ +   I+HL FADD
Sbjct: 24  PSRGLRQGDPLSPYLFILCTEVLSGLCRRAQEQGRLPGIRVSNNSPRINHLLFADD 79


>PO23_POPJA (Q05118) Retrovirus-related Pol polyprotein from type I
           retrotransposable element R2 [Contains: Reverse
           transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)
          Length = 606

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 83/188 (43%), Gaps = 17/188 (9%)

Query: 4   TRDNIILAQEVMHTIHTQK-KGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDL 62
           T  NII+ +   H I  ++ KG+    + +D+ KA+D VS   +   +  FG    + D 
Sbjct: 2   TLANIIMLE---HYIKLRRLKGKTYNVVSLDIRKAFDTVSHPAILRAMRAFGIDDGMQDF 58

Query: 63  IMWGVKCPKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWK 122
           IM  +     +I+           + G++QGDPLSP LF + ++ L  ++ +     +  
Sbjct: 59  IMSTITDAYTNIVVGGRTTNKIYIRNGVKQGDPLSPVLFNIVLDELVTRLNDEQPGASMT 118

Query: 123 PVRITKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFC---EASGMKVNLDKSRML 179
           P         I+ L FADD+LL      +    V N+L   C      GM +N +K   +
Sbjct: 119 P------ACKIASLAFADDLLLLEDRDID----VPNSLATTCAYFRTRGMTLNPEKCASI 168

Query: 180 FSKAVDHR 187
            +  V  R
Sbjct: 169 SAATVSGR 176


>PO21_NASVI (Q03278) Retrovirus-related Pol polyprotein from type I
           retrotransposable element R2 [Contains: Reverse
           transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)
          Length = 1025

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 18/197 (9%)

Query: 23  KGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMWGVKCPKLSILWNCSKLP 82
           K +GL    +D++KA+D V    +   L     P  + + IMW  +  K  +    +K  
Sbjct: 446 KIKGLYIAILDVKKAFDSVEHRSILDALRRKKLPLEMRNYIMWVYRNSKTRLEVVKTKGR 505

Query: 83  SFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDV 142
              P RG+RQGDPLSP LF   M+     +   + + T   +   K G     L FADD+
Sbjct: 506 WIRPARGVRQGDPLSPLLFNCVMD----AVLRRLPENTGFLMGAEKIGA----LVFADDL 557

Query: 143 LLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLFSKAVDHRRQINLS----HIAGI 198
           +L  + ++E LQ   + ++   +  G+++   K   L        ++I +        G 
Sbjct: 558 VLLAE-TREGLQASLSRIEAGLQEQGLEMMPRKCHTLALVPSGKEKKIKVETHKPFTVGN 616

Query: 199 SRASDLG-----KYLGI 210
              + LG     KYLG+
Sbjct: 617 QEITQLGHADQWKYLGV 633


>PO22_POPJA (Q03274) Retrovirus-related Pol polyprotein from type I
           retrotransposable element R2 [Contains: Reverse
           transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)
          Length = 711

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/171 (28%), Positives = 77/171 (44%), Gaps = 10/171 (5%)

Query: 7   NIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMWG 66
           N +L    + +   Q+K   +V++  D+ KA+D VS   +   L   G      + I   
Sbjct: 119 NSLLLDTYISSRREQRKTYNVVSL--DVRKAFDTVSHSSICRALQRLGIDEGTSNYITGS 176

Query: 67  VKCPKLSI-LWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVR 125
           +     +I +   S+      +RG++QGDPLSP+LF   ++ L   +Q+  T G    + 
Sbjct: 177 LSDSTTTIRVGPGSQTRKICIRRGVKQGDPLSPFLFNAVLDELLCSLQS--TPGIGGTIG 234

Query: 126 ITKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKS 176
             K    I  L FADD+LL  + +   L     T+  F    GM +N  KS
Sbjct: 235 EEK----IPVLAFADDLLLL-EDNDVLLPTTLATVANFFRLRGMSLNAKKS 280


>PO21_SCICO (Q03279) Retrovirus-related Pol polyprotein from type I
           retrotransposable element R2 [Contains: Reverse
           transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)
          Length = 869

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 52/193 (26%), Positives = 80/193 (40%), Gaps = 29/193 (15%)

Query: 32  IDLEKAYDRVSWDFLRATLYDFGFPPRIVDLI--MWGVKCPKLSILWNCSKLPSFAPQRG 89
           +DL KA++ V    L   + + G PP +VD I  M+     ++     C      A   G
Sbjct: 296 LDLVKAFNSVYHSALIDAITEAGCPPGVVDYIADMYNNVITEMQFEGKCELASILA---G 352

Query: 90  LRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDVLLFCQ-- 147
           + QGDPLS  LF L  E+    + N   +G     R     V ++   ++DD LL     
Sbjct: 353 VYQGDPLSGPLFTLAYEKALRALNN---EG-----RFDIADVRVNASAYSDDGLLLAMTV 404

Query: 148 -ASKEQLQLVNNTLKEFCEASGMKVNLDKSRMLF---------SKAVDHRRQINLSHIAG 197
              +  L     TL +     G+++N  KS+ +           K V +RR +  +    
Sbjct: 405 IGLQHNLDKFGETLAKI----GLRINSRKSKTVSLVPSGREKKMKIVSNRRLLLKASELK 460

Query: 198 ISRASDLGKYLGI 210
               SDL KYLG+
Sbjct: 461 PLTISDLWKYLGV 473


>RT16_MYXXA (P23072) RNA-directed DNA polymerase from retron
           Mx162-RT (EC 2.7.7.49) (Reverse transcriptase)
           (Mx162-RT)
          Length = 485

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 34/161 (21%), Positives = 67/161 (41%), Gaps = 22/161 (13%)

Query: 28  VAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLI-MWGVKCPKLSILWNCSKLPSFAP 86
           V +K+DL+  +  V+W  ++  L   G       L+ +   + P+ ++ +    L     
Sbjct: 245 VVVKVDLKDFFPSVTWRRVKGLLRKGGLREGTSTLLSLLSTEAPREAVQFRGKLLHVAKG 304

Query: 87  QRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDVLLFC 146
            R L QG P SP             I N +     K +      +G ++  +ADD+    
Sbjct: 305 PRALPQGAPTSP------------GITNALCLKLDKRLSALAKRLGFTYTRYADDLTFSW 352

Query: 147 QASKE---------QLQLVNNTLKEFCEASGMKVNLDKSRM 178
             +K+          + ++ + ++E  EA G +V+ DK+R+
Sbjct: 353 TKAKQPKPRRTQRPPVAVLLSRVQEVVEAEGFRVHPDKTRV 393


>HEM1_OCEIH (Q8EPM7) Glutamyl-tRNA reductase (EC 1.2.1.-) (GluTR)
          Length = 457

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 17/56 (30%), Positives = 28/56 (49%)

Query: 6   DNIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVD 61
           D+I++ +E+M  +  Q+KGR L  + I + +  D    +     LYD      IVD
Sbjct: 253 DSIVVTKEMMEKVQKQRKGRALFLVDIAVPRDMDPAISELENVFLYDIDNLQHIVD 308


>CH62_CHLCV (P59698) 60 kDa chaperonin 2 (Protein Cpn60 2) (groEL
           protein 2)
          Length = 536

 Score = 32.7 bits (73), Expect = 0.86
 Identities = 21/73 (28%), Positives = 31/73 (41%), Gaps = 13/73 (17%)

Query: 63  IMWGVKC-------PKLSILWNCSKLPSFAPQRGLRQGDPLSPYLFVLCMERLAIQIQNL 115
           +M+G KC       P   +  NC K P +     L+  DP   Y    C+       +NL
Sbjct: 437 VMFGCKCMLQSAEEPLRVLATNCGKDPEYVVDTVLKHADP---YFGYNCIND---SFENL 490

Query: 116 VTQGTWKPVRITK 128
           +T G + P  +TK
Sbjct: 491 ITSGVFDPFSVTK 503


>MTB5_NEIGO (Q59605) Modification methylase NgoBV (EC 2.1.1.37)
           (Cytosine-specific methyltransferase NgoBV) (M.NgoBV)
           (M.NgoV)
          Length = 423

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 17/158 (10%)

Query: 20  TQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMWGVKCPKLSILWNCS 79
           TQK GR L  I   LE     VSW  L A   +FG P     + + G    K  + +  S
Sbjct: 132 TQKIGRTLTVILETLEALGYYVSWKVLNAK--EFGIPQNRKRIYLTGSLKSKPDLSFETS 189

Query: 80  KLPSFAPQRGLRQGDPL--SPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLF 137
             P    +  L  G P   SP++  L  +    ++            +  KD  G  +  
Sbjct: 190 PSPKL--KNILESGLPTESSPFIKKLLKKFPPSELYG----------KSVKDKRGGKNNI 237

Query: 138 FADDVLLFCQASKEQLQLVNNTLKEFCEASGM-KVNLD 174
            + D+ L    ++E+ QL+N  LKE  + +G+ K+ +D
Sbjct: 238 HSWDIELKGAVTEEEKQLLNILLKERRKKNGLQKIGID 275


>PO12_NASVI (Q03270) Retrovirus-related Pol polyprotein from type I
           retrotransposable element R1 [Contains: Reverse
           transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)
          Length = 410

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 26/162 (16%)

Query: 89  GLRQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDVLLFCQA 148
           G  QG    P L+ L M  + I++                 G G+S   FADDV +  + 
Sbjct: 1   GCPQGSIGGPILWNLSMNGMLIELA----------------GSGVSVCAFADDVAILAEG 44

Query: 149 S--KEQLQLVNNTLK---EFCEASGMKVNLDKS--RMLFSKAVDHRRQINLSHIAGISRA 201
           +  KE  +++N  ++   ++ E  G+ V+ +K+   +L  K V   R + +S    + + 
Sbjct: 45  NTRKEVERVINEKMEIVYKWGEKMGVSVSEEKTVCMLLKGKYVTSNRAVRVSKTINVYKR 104

Query: 202 ---SDLGKYLGIPLLKGRVTKAHFASLIGKMSSRLTSWKNNL 240
                  +YLG+ + +G     H   +  K++  +   K  L
Sbjct: 105 IKYVSCFRYLGVNVTEGMGFGEHVRGMKVKVAKGVQKLKRVL 146


>IRA2_YEAST (P19158) Inhibitory regulator protein IRA2
          Length = 3079

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 22/63 (34%), Positives = 33/63 (51%), Gaps = 8/63 (12%)

Query: 169  MKVNLDKSRMLFSKAVDHRRQINLSHIAGISRASDLGKY------LGIPLLKGRVTKAHF 222
            +K+N +K ++L    V   +    SH+AGI+ AS   +Y      L  PL+ G V +A F
Sbjct: 1151 LKINNEKRQILLDITVKFMKV--RSHLAGIAEASHHMEYISDSEKLTFPLIMGTVGRALF 1208

Query: 223  ASL 225
             SL
Sbjct: 1209 VSL 1211


>Y2R2_DROME (P16425) Hypothetical 115 kDa protein in type I
           retrotransposable element R1DM (ORF 2)
          Length = 1021

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 44/204 (21%), Positives = 78/204 (37%), Gaps = 26/204 (12%)

Query: 32  IDLEKAYDRVSWDFLRATLYDFGFPPRIVDLIMW-GVKCPKLSILWNCSKLPSFAPQRGL 90
           +D + A+D V W    + L D G      ++ +W      + +++ + S        RG 
Sbjct: 577 VDFKGAFDNVEWSAALSRLADLG----CREMGLWQSFFSGRRAVIRSSSGTVEVPVTRGC 632

Query: 91  RQGDPLSPYLFVLCMERLAIQIQNLVTQGTWKPVRITKDGVGISHLFFADDVLLFCQA-S 149
            QG    P+++ + M+ L  ++Q                        +ADD+LL  +  S
Sbjct: 633 PQGSISGPFIWDILMDVLLQRLQPYCQLSA-----------------YADDLLLLVEGNS 675

Query: 150 KEQLQLVNNTLKEFCEASGMKVN--LDKSRMLFSKAVDHRRQINLSHIAGISRASDLG-K 206
           +  L+     L    E  G +V   L  S+ +        R+      AG +       +
Sbjct: 676 RAVLEEKGAQLMSIVETWGAEVGDCLSTSKTVIMLLKGALRRAPTVRFAGRNLPYVRSCR 735

Query: 207 YLGIPLLKGRVTKAHFASLIGKMS 230
           YLGI + +G     H ASL  +M+
Sbjct: 736 YLGITVSEGMKFLTHIASLRQRMT 759


>ARH1_HUMAN (Q92888) Rho guanine nucleotide exchange factor 1
           (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide
           exchange factor) (Sub1.5)
          Length = 912

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 20/56 (35%), Positives = 30/56 (52%), Gaps = 5/56 (8%)

Query: 106 ERLAIQIQNLVTQG--TWKPVRITKDGVGISHLFFADDVLLFCQASKEQLQLVNNT 159
           + L I  + LV +G  TW   R+TKD     H+   DD+LL  Q   E+L L +++
Sbjct: 639 KNLDITKKKLVHEGPLTW---RVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHS 691


>YMH5_CAEEL (P34472) Hypothetical protein F58A4.5 in chromosome III
          Length = 1222

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 46/208 (22%), Positives = 82/208 (39%), Gaps = 23/208 (11%)

Query: 1   FLATRDNIILAQEVMHTIHTQKKGRGLVAIKIDLEKAYDRVSWDFLRATLYDFGFPPRIV 60
           F +   +++ +  + H+I   K  + L  +  D  KA+D+VS   L   L  FG      
Sbjct: 724 FRSCPSSLVRSISLYHSI--LKNEKSLDILFFDFAKAFDKVSHPILLKKLALFGLDKLTC 781

Query: 61  DLIMWGVKCPKLSILWNCSKLPSFAP-QRGLRQGDPLSPYLFVLCMERLAIQIQNLVTQG 119
                 +     S+  N     +  P   G+ QG    P LF+L +  L I ++      
Sbjct: 782 SWFKEFLHLRTFSVKINKFVSSNAYPISSGVPQGSVSGPLLFILFINDLLIDLE------ 835

Query: 120 TWKPVRITKDGVGISHLFFADDVLLFCQASKEQLQLVNNTLKEFCEASGMKVNLDKSRML 179
                        I    FADD+ +F   +   LQ   +T+ ++ + + + +   KS +L
Sbjct: 836 -----------PNIHVSCFADDIKIF-HHNPSTLQNSIDTIVKWSKKNKLPLAPAKSSVL 883

Query: 180 F--SKAVDHRRQINLSHIAGISRASDLG 205
              S+  +H  +++   I   S   DLG
Sbjct: 884 SLGSRNSNHTYRVDNVPILPSSTVRDLG 911


>VG12_BPPZA (P07537) Pre-neck appendage protein (Late protein GP12)
          Length = 854

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 25/79 (31%), Positives = 36/79 (44%), Gaps = 2/79 (2%)

Query: 167 SGMKVNLDKSRMLFSKAVDHRRQINLSHIAGISRASDLGKYLGIPLLKGRVTKAHFASLI 226
           SG + ++ KS +L S +     + +L  IAG S +   G Y  I    G V    FA LI
Sbjct: 575 SGCEASVSKSGILTSSSSKTSSERSL--IAGSSTSEATGTYNTILGSLGAVADEQFAGLI 632

Query: 227 GKMSSRLTSWKNNLLNRAG 245
               SR +   N +L+  G
Sbjct: 633 SASQSRASGNHNLILSSYG 651


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.325    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,425,444
Number of Sequences: 164201
Number of extensions: 1141219
Number of successful extensions: 3232
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3207
Number of HSP's gapped (non-prelim): 27
length of query: 253
length of database: 59,974,054
effective HSP length: 108
effective length of query: 145
effective length of database: 42,240,346
effective search space: 6124850170
effective search space used: 6124850170
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)