BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0348.6
         (408 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)          277  4e-74
ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)                158  2e-38
ANT3_SHEEP (P32262) Antithrombin-III precursor (ATIII)                157  5e-38
ANT3_BOVIN (P41361) Antithrombin-III (ATIII)                          156  1e-37
SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)      152  1e-36
ANT3_HUMAN (P01008) Antithrombin-III precursor (ATIII) (PRO0309)      152  1e-36
ILEU_HUMAN (P30740) Leukocyte elastase inhibitor (LEI) (Monocyte...   146  1e-34
SCC2_HUMAN (P48594) Squamous cell carcinoma antigen 2 (SCCA-2) (...   144  3e-34
PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic an...   144  3e-34
NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)       144  4e-34
ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte ...   144  4e-34
ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)                143  9e-34
NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)                  142  1e-33
SCC1_HUMAN (P29508) Squamous cell carcinoma antigen 1 (SCCA-1) (...   140  6e-33
PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease inhib...   140  8e-33
SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3) ...   137  6e-32
SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2) ...   137  6e-32
NEUS_HUMAN (Q99574) Neuroserpin precursor (Protease inhibitor 12)     136  8e-32
NEUS_MOUSE (O35684) Neuroserpin precursor (Protease inhibitor 17)     135  1e-31
SB12_HUMAN (Q96P63) Serpin B12                                        133  9e-31

>PRTZ_HORVU (P06293) Protein Z (Z4) (Major endosperm albumin)
          Length = 399

 Score =  277 bits (708), Expect = 4e-74
 Identities = 162/391 (41%), Positives = 236/391 (59%), Gaps = 14/391 (3%)

Query: 12  QSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLR---FDS 68
           Q+  AL     + S  +    N+ FSPLSL+ ALS++ AG+   T D+L++ L       
Sbjct: 16  QTRFALRLRSAISSNPERAAGNVAFSPLSLHVALSLITAGAAA-TRDQLVAILGDGGAGD 74

Query: 69  IDHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASL 128
              LN    Q +  V ++E     P    ++F NG+F+D ++SL   F  L    Y A  
Sbjct: 75  AKELNALAEQVVQFVLANESSTGGP---RIAFANGIFVDASLSLKPSFEELAVCQYKAKT 131

Query: 129 ASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLD 188
            S+DF  +    +  VNS +EQ + GLI Q+LPPG+V N TKLI  NAL F+G W    D
Sbjct: 132 QSVDFQHKTLEAVGQVNSWVEQVTTGLIKQILPPGSVDNTTKLILGNALYFKGAWDQKFD 191

Query: 189 -GLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFSMCIFL 247
              T   SF+LL G+S++  +M++ KK QY+ + D  K+L+LPY +G D+ R+FSM I L
Sbjct: 192 ESNTKCDSFHLLDGSSIQTQFMSSTKK-QYISSSDNLKVLKLPYAKGHDK-RQFSMYILL 249

Query: 248 PDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSP 307
           P AQDGL +L ++LS+EP F++  +P + V V  F++PKF IS+ FEAS++L+ +G+  P
Sbjct: 250 PGAQDGLWSLAKRLSTEPEFIENHIPKQTVEVGRFQLPKFKISYQFEASSLLRALGLQLP 309

Query: 308 FSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPS 367
           FS  +A  ++MV+    S  L +  +FHK+F+EVNE+GT+A AAT +             
Sbjct: 310 FSE-EADLSEMVD---SSQGLEISHVFHKSFVEVNEEGTEAGAATVAMGVAMSMPLKVDL 365

Query: 368 IDFIADHPFLFLIREDFTGTILFVGQVLNPL 398
           +DF+A+HPFLFLIRED  G ++FVG V NPL
Sbjct: 366 VDFVANHPFLFLIREDIAGVVVFVGHVTNPL 396


>ANT3_MOUSE (P32261) Antithrombin-III precursor (ATIII)
          Length = 465

 Score =  158 bits (400), Expect = 2e-38
 Identities = 113/396 (28%), Positives = 198/396 (49%), Gaps = 25/396 (6%)

Query: 9   TRCQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDS 68
           ++  S  A +F +HL   ++  + N+  SPLS+  A ++   G+   TL +L+   +FD+
Sbjct: 85  SKANSRFATNFYQHLADSKNDND-NIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDT 143

Query: 69  I-----DHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTH 123
           I     D ++ +F++    ++   + +S      L   N +F D +++ +  ++ +    
Sbjct: 144 ISEKTSDQIHFFFAKLNCRLYRKANKSSD-----LVSANRLFGDKSLTFNESYQDVSEVV 198

Query: 124 YNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMW 183
           Y A L  LDF    +     +N+ +  ++ G I  ++P G +  LT L+  N + F+G+W
Sbjct: 199 YGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLW 258

Query: 184 KHTLD-GLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFS 242
           K       T    F  + G S  VP M    K +Y R  +G ++L LP+K G D     +
Sbjct: 259 KSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFK-GDD----IT 313

Query: 243 MCIFLPDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEV 302
           M + LP  +  L+ + Q+L+  P  L+  L      +    +P+F     F     L+++
Sbjct: 314 MVLILPKPEKSLAKVEQELT--PELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDM 371

Query: 303 GVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCAR 362
           G++  FSP  +    +  V    D+L+V   FHKAF+EVNE+G++A A+T   +     R
Sbjct: 372 GLIDLFSPEKSQLPGI--VAGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVIT---GR 426

Query: 363 DHHPS-IDFIADHPFLFLIREDFTGTILFVGQVLNP 397
             +P+ + F A+ PFL LIRE    TI+F+G+V NP
Sbjct: 427 SLNPNRVTFKANRPFLVLIREVALNTIIFMGRVANP 462


>ANT3_SHEEP (P32262) Antithrombin-III precursor (ATIII)
          Length = 465

 Score =  157 bits (397), Expect = 5e-38
 Identities = 112/395 (28%), Positives = 196/395 (49%), Gaps = 23/395 (5%)

Query: 9   TRCQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDS 68
           ++  S  A +F +HL   ++  + N+  SPLS+  A ++   G+   TL +L+   +FD+
Sbjct: 85  SKANSHFATAFYQHLADSKNNND-NIFLSPLSISTAFAMTKLGACNNTLKQLMEVFKFDT 143

Query: 69  I-----DHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTH 123
           I     D ++ +F++    ++   + +S      L   N +F D +++ +  ++ +    
Sbjct: 144 ISEKTSDQIHFFFAKLNCRLYRKANKSSE-----LVSANRLFGDKSITFNETYQDISEVV 198

Query: 124 YNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMW 183
           Y A L  LDF    +     +N  I  ++ G IT ++PP  +   T L+  N + F+G+W
Sbjct: 199 YGAKLQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQAIDEFTVLVLVNTIYFKGLW 258

Query: 184 KHTLD-GLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFS 242
           K       T    F    G S  VP M    K +Y R  +G ++L LP+K G D     +
Sbjct: 259 KSKFSPENTKKELFYKADGESCSVPMMYQEGKFRYRRVAEGTQVLELPFK-GDD----IT 313

Query: 243 MCIFLPDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEV 302
           M + LP  +  L+ + ++L+  P  L+  L      +    +P F I  +F     L+++
Sbjct: 314 MVLILPKLEKPLAKVERELT--PDMLQEWLDELTETLLVVHMPHFRIEDSFSVKEQLQDM 371

Query: 303 GVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCAR 362
           G+   FSP  +    +  V    ++L+V   FHKAF+EVNE+G++A A+T  ++A +   
Sbjct: 372 GLEDLFSPEKSRLPGI--VAEGRNDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLN 429

Query: 363 DHHPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
            +   + F A+ PFL LIRE    TI+F+G+V NP
Sbjct: 430 LNR--VTFQANRPFLVLIREVALNTIIFMGRVANP 462


>ANT3_BOVIN (P41361) Antithrombin-III (ATIII)
          Length = 433

 Score =  156 bits (394), Expect = 1e-37
 Identities = 113/395 (28%), Positives = 194/395 (48%), Gaps = 23/395 (5%)

Query: 9   TRCQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDS 68
           ++  S  A +F +HL   ++  + N+  SPLS+  A ++   G+   TL +L+   +FD+
Sbjct: 53  SKANSHFATAFYQHLADSKNNND-NIFLSPLSISTAFAMTKLGACNNTLTQLMEVFKFDT 111

Query: 69  I-----DHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTH 123
           I     D ++ +F++    ++   + +S      L   N +F D +++ +  ++ +    
Sbjct: 112 ISEKTSDQIHFFFAKLNCRLYRKANKSSE-----LVSANRLFGDKSITFNETYQDISEVV 166

Query: 124 YNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMW 183
           Y A L  LDF    +     +N  I  ++ G IT ++PP  +   T L+  N + F+G+W
Sbjct: 167 YGAKLQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLW 226

Query: 184 KHTLD-GLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFS 242
           K       T    F    G S  V  M    K +Y R  +  ++L LP+K G D     +
Sbjct: 227 KSKFSPENTRKELFYKADGESCSVLMMYQESKFRYRRVAESTQVLELPFK-GDD----IT 281

Query: 243 MCIFLPDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEV 302
           M + LP  +  L+ + Q+L+  P  L+  L      +    +P+F I  +F     L+++
Sbjct: 282 MVLILPKLEKTLAKVEQELT--PDMLQEWLDELTETLLVVHMPRFRIEDSFSVKEQLQDM 339

Query: 303 GVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCAR 362
           G+   FSP  +    +V     SD L+V   FHKAF+EVNE+G++A A+T  ++A +   
Sbjct: 340 GLEDLFSPEKSRLPGIV-AEGRSD-LYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLN 397

Query: 363 DHHPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
                + F A+ PFL LIRE    TI+F+G+V NP
Sbjct: 398 SDR--VTFKANRPFLVLIREVALNTIIFMGRVANP 430


>SB10_HUMAN (P48595) Bomapin (Protease inhibitor 10) (Serpin B10)
          Length = 397

 Score =  152 bits (385), Expect = 1e-36
 Identities = 113/406 (27%), Positives = 196/406 (47%), Gaps = 44/406 (10%)

Query: 16  ALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFD-------- 67
           AL  +K L   E  Q KN+ FS  S+  +L+++  G++G T  ++   L+F+        
Sbjct: 12  ALELSKKL--AESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCD 69

Query: 68  --------------SIDHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLS 113
                         + + +++ F   IS +    D       + L   N ++ + T +  
Sbjct: 70  PESEKKRKMEFNLSNSEEIHSDFQTLISEILKPND------DYLLKTANAIYGEKTYAFH 123

Query: 114 YPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIF 173
             +   + T++ A    ++F    D +  D+NS +E+++ G I  LLP  +V + T++I 
Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183

Query: 174 ANALRFQGMWKHTLDGLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKI--LRLPY 231
            NAL F+G+W+H             ++ T+ K   M   KK  ++   +  K   L+L Y
Sbjct: 184 VNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYY 243

Query: 232 KQGRDRQRRFSMCIFLPDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISF 291
           K      R  S+ I LP+  +GL  L + ++ E           ++      +PKF +  
Sbjct: 244 K-----SRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLED 298

Query: 292 TFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAA 351
           +++  + L  +G+   FS   A F+ M    S + NLF+ ++FHKAF+E+NE+GT+A A 
Sbjct: 299 SYDLKSTLSSMGMSDAFSQSKADFSGM----SSARNLFLSNVFHKAFVEINEQGTEAAAG 354

Query: 352 TWSALARQCARDHHPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
           + S +     R   PSI+F A+HPFLF IR + T TILF G++ +P
Sbjct: 355 SGSEID---IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>ANT3_HUMAN (P01008) Antithrombin-III precursor (ATIII) (PRO0309)
          Length = 464

 Score =  152 bits (385), Expect = 1e-36
 Identities = 112/396 (28%), Positives = 196/396 (49%), Gaps = 25/396 (6%)

Query: 9   TRCQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDS 68
           ++  S  A +F +HL   ++  + N+  SPLS+  A ++   G+   TL +L+   +FD+
Sbjct: 84  SKANSRFATTFYQHLADSKNDND-NIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT 142

Query: 69  I-----DHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTH 123
           I     D ++ +F++    ++   + +S      L   N +F D +++ +  ++ +    
Sbjct: 143 ISEKTSDQIHFFFAKLNCRLYRKANKSSK-----LVSANRLFGDKSLTFNETYQDISELV 197

Query: 124 YNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMW 183
           Y A L  LDF    +     +N  +  ++ G IT ++P   +  LT L+  N + F+G+W
Sbjct: 198 YGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLW 257

Query: 184 KHTLD-GLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFS 242
           K       T    F    G S     M    K +Y R  +G ++L LP+K G D     +
Sbjct: 258 KSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFK-GDD----IT 312

Query: 243 MCIFLPDAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEV 302
           M + LP  +  L+ + ++L+  P  L+  L   +  +    +P+F I   F     L+++
Sbjct: 313 MVLILPKPEKSLAKVEKELT--PEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDM 370

Query: 303 GVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCAR 362
           G+V  FSP  +    +  V    D+L+V   FHKAF+EVNE+G++A A+T   +A    R
Sbjct: 371 GLVDLFSPEKSKLPGI--VAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIA---GR 425

Query: 363 DHHPS-IDFIADHPFLFLIREDFTGTILFVGQVLNP 397
             +P+ + F A+ PFL  IRE    TI+F+G+V NP
Sbjct: 426 SLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 461


>ILEU_HUMAN (P30740) Leukocyte elastase inhibitor (LEI)
           (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI)
          Length = 379

 Score =  146 bits (368), Expect = 1e-34
 Identities = 118/406 (29%), Positives = 196/406 (48%), Gaps = 36/406 (8%)

Query: 1   MEIQKSKSTRCQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDEL 60
           ME   S +TR   D+ L+ +      E+    N+  SP S+ +A++++  G+ G T  +L
Sbjct: 1   MEQLSSANTRFALDLFLALS------ENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQL 54

Query: 61  LSFLRFDSIDHLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLL 120
                F++++ +++ F         + D     + + L   N ++ + T +    F    
Sbjct: 55  SKTFHFNTVEEVHSRFQS------LNADINKRGASYILKLANRLYGEKTYNFLPEFLVST 108

Query: 121 STHYNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQ 180
              Y A LAS+DF    +     +N  ++ ++ G I +LL  G V N+TKL+  NA+ F+
Sbjct: 109 QKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFK 168

Query: 181 GMWKHT-LDGLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFD-GFKILRLPYKQGRDRQ 238
           G WK   +   T  + F L       V  M   KK  Y    D   ++L LPY QG +  
Sbjct: 169 GNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPY-QGEE-- 225

Query: 239 RRFSMCIFLPDAQDGLSALIQKLSSEPGFLK-------GKLPHRKVRVRPFRVPKFNISF 291
              SM I LPD  +  S  ++K+  +    K         L   +V V    +P+F +  
Sbjct: 226 --LSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNV---SLPRFKLEE 280

Query: 292 TFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAA 351
           ++  ++ L  +GV   F+   A  + M    S + ++F+  I HK+F+EVNE+GT+A AA
Sbjct: 281 SYTLNSDLARLGVQDLFNSSKADLSGM----SGARDIFISKIVHKSFVEVNEEGTEAAAA 336

Query: 352 TWSALARQCARDHHPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
           T + +A  C     P  +F ADHPFLF IR + +G+ILF+G+  +P
Sbjct: 337 T-AGIATFCML--MPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379


>SCC2_HUMAN (P48594) Squamous cell carcinoma antigen 2 (SCCA-2)
           (Leupin)
          Length = 390

 Score =  144 bits (364), Expect = 3e-34
 Identities = 107/389 (27%), Positives = 181/389 (46%), Gaps = 42/389 (10%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSI-----DHLNTYFSQGISPVF 84
           +E N+ +SP+S+ +AL ++  G++  T  ++   L FD +     +   TY       V 
Sbjct: 23  KENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVH 82

Query: 85  SDEDPA-----SSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDS 139
                       S   + L   N +F + T      +   +   Y  S+ S DF    + 
Sbjct: 83  HQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEE 142

Query: 140 VLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLDGLTHVSSFNLL 199
               +NS +E ++N  I  L P GT+ N T L+  NA+ F+G W+         + F   
Sbjct: 143 SRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWE---------NKFKKE 193

Query: 200 SGTSVKV-PYMTTFKKTQYVRAFDGF----------KILRLPYKQGRDRQRRFSMCIFLP 248
           +    K  P   T+K  Q +R ++ F          K+L +PYK G+D     SM + LP
Sbjct: 194 NTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYK-GKD----LSMIVLLP 248

Query: 249 DAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPF 308
           +  DGL  L +KL++E       L + +       +P+F +  +++  + L+ +G+V+ F
Sbjct: 249 NEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIF 308

Query: 309 SPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSI 368
           +  DA  + M    + S  L V  + HKAF+EV E+G +A AAT   +    +   +   
Sbjct: 309 NG-DADLSGM----TWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNE-- 361

Query: 369 DFIADHPFLFLIREDFTGTILFVGQVLNP 397
           +F  +HPFLF IR++ T +ILF G+  +P
Sbjct: 362 EFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>PTI6_HUMAN (P35237) Placental thrombin inhibitor (Cytoplasmic
           antiproteinase) (CAP) (Protease inhibitor 6) (PI-6)
          Length = 376

 Score =  144 bits (364), Expect = 3e-34
 Identities = 109/370 (29%), Positives = 177/370 (47%), Gaps = 22/370 (5%)

Query: 32  KNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTYFSQGISPVFSDEDPAS 91
           KN+ FSP+S+  AL+++  G++G T  ++   L F+          QG   + ++ +   
Sbjct: 25  KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGD-IHQGFQSLLTEVNKTG 83

Query: 92  SPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLIEQE 151
           +  Q+ L   N +F + +      FR      Y A +  LDF    +     +N+ + ++
Sbjct: 84  T--QYLLRVANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEK 141

Query: 152 SNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLD-GLTHVSSFNLLSGTSVKVPYM- 209
           + G I +LL PG+V  LT+L+  NA+ F+G W    D   T    F +       V  M 
Sbjct: 142 TEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMF 201

Query: 210 --TTFKKTQYVRAFDGFKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQKLSSEPGF 267
             +TFKKT     F   +IL LPY       +  +M I LPD    L  + ++L+ E   
Sbjct: 202 KQSTFKKTYIGEIFT--QILVLPYV-----GKELNMIIMLPDETTDLRTVEKELTYEKFV 254

Query: 268 LKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSDN 327
              +L           +P+F +  +++  +VL+ +G+   F    A F+ M        +
Sbjct: 255 EWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM-----SQTD 309

Query: 328 LFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSIDFIADHPFLFLIREDFTGT 387
           L +  + HK+F+EVNE+GT+A AAT + +  +CAR   P   F ADHPFLF I+   T  
Sbjct: 310 LSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCAR-FVPR--FCADHPFLFFIQHSKTNG 366

Query: 388 ILFVGQVLNP 397
           ILF G+  +P
Sbjct: 367 ILFCGRFSSP 376


>NEUS_RAT (Q9JLD2) Neuroserpin precursor (Protease inhibitor 17)
          Length = 410

 Score =  144 bits (363), Expect = 4e-34
 Identities = 109/378 (28%), Positives = 189/378 (49%), Gaps = 32/378 (8%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTY-FSQGISPVFSDED 88
           +++N++FSPLS+  A+ VM  G++G TL E+   + ++S+     + F +  S + S E+
Sbjct: 42  EDENILFSPLSIALAMGVMELGAQGSTLKEIRHSMGYESLKSGEEFSFLRDFSSMVSAEE 101

Query: 89  PASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLI 148
                 Q+ +   N +F+     ++  F +++  ++NA +  +DF+    +V + +N  +
Sbjct: 102 -----GQYVMKIANSLFVQNGFHINEEFLQMMKMYFNAEVNHVDFS-ENVAVANYINKWV 155

Query: 149 EQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTL-DGLTHVSSFNLLSGTSVKVP 207
           E  +N L+  L+ PG    +T L   NA+ F+G WK       T   SF     + V++P
Sbjct: 156 ENYTNSLLKDLVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIP 215

Query: 208 YMTTFKKTQYVRAFDG-------FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQK 260
            M    +  Y    DG       +++L +PY+         SM + L   +  L+ L   
Sbjct: 216 MMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE-----ISMMLVLSRQEVPLATLEPL 270

Query: 261 LSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVN 320
           L  +P  ++      K +     +P+F +    +  ++LK +GV   F   DA+ T M  
Sbjct: 271 L--KPQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIK-DANLTAM-- 325

Query: 321 VNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWS-ALARQCARDHHPSIDFIADHPFLFL 379
             S    LF+    HK+FIEVNE+G++A  A+   A++R       P +  I DHPFLFL
Sbjct: 326 --SDKKELFLSKAVHKSFIEVNEEGSEAAVASGMIAISRMAVL--FPQV--IVDHPFLFL 379

Query: 380 IREDFTGTILFVGQVLNP 397
           I+   TGTILF+G+V++P
Sbjct: 380 IKNRKTGTILFMGRVMHP 397


>ILEU_PIG (P80229) Leukocyte elastase inhibitor (LEI) (Leucocyte
           neutral proteinase inhibitor) (LNPI)
          Length = 378

 Score =  144 bits (363), Expect = 4e-34
 Identities = 112/372 (30%), Positives = 180/372 (48%), Gaps = 27/372 (7%)

Query: 33  NLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTYFSQGISPVFSDEDPASS 92
           N+  SP S+ +AL+++  G+ G T  ++   L FD++  +++ F         + D    
Sbjct: 27  NIFISPFSISSALAMILLGTRGNTEAQMSKALHFDTVKDIHSRFQS------LNADINKC 80

Query: 93  PSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLIEQES 152
            + + L   N +F + T      F       Y A LAS+DF    +     +N  +++++
Sbjct: 81  GASYILKLANRLFGEKTYHFLPEFLASTQKTYGAELASVDFLRASEEARKAINEWVKEQT 140

Query: 153 NGLITQLLPPGTVTNLTKLIFANALRFQGMWKHT-LDGLTHVSSFNLLSGTSVKVPYMTT 211
            G I +LL  G V + TKL+  NA+ F+G W+   +   T  + F L    S  V  M  
Sbjct: 141 EGKIPELLASGVVDSATKLVLVNAIYFKGSWQEKFMTEATKDAPFRLNKKDSKTVKMMYQ 200

Query: 212 FKKTQ--YVRAFDGFKILRLPYKQGRDRQRRFSMCIFLPDA----QDGLSALIQKLSSEP 265
            KK    Y++     ++L LPY QG+D     SM I LPD+      GL  + Q L+ E 
Sbjct: 201 KKKFPFGYIKELK-CRVLELPY-QGKD----LSMVILLPDSIEDESTGLRKIEQHLTLEK 254

Query: 266 GFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPS 325
                K  + ++      +P+F +  +++ +  L  +GV   F    A  T M    S +
Sbjct: 255 LNEWTKPDNLELLEVNVHLPRFRLEESYDLNAPLARLGVQDLFGSR-ADLTGM----SEA 309

Query: 326 DNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSIDFIADHPFLFLIREDFT 385
            +LF+  + HKAF+EVNE+GT+A AAT             P  DFIADHPF+F IR + +
Sbjct: 310 RDLFISKVVHKAFVEVNEEGTEAAAATAGIAVFAMLM---PEEDFIADHPFIFFIRHNPS 366

Query: 386 GTILFVGQVLNP 397
             ILF+G++ +P
Sbjct: 367 SNILFLGRLSSP 378


>ILEU_HORSE (P05619) Leukocyte elastase inhibitor (LEI)
          Length = 379

 Score =  143 bits (360), Expect = 9e-34
 Identities = 107/371 (28%), Positives = 186/371 (49%), Gaps = 24/371 (6%)

Query: 33  NLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTYFSQGISPVFSDEDPASS 92
           N+  SPLS+ +AL+++  G+ G T  ++   L FD+++ +++ F      + +D +   +
Sbjct: 27  NIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDTVEDIHSRFQS----LNADINKPGA 82

Query: 93  PSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLIEQES 152
           P  + L   N ++ + T +    F       Y A LAS+DF    +    ++N  ++ ++
Sbjct: 83  P--YILKLANRLYGEKTYNFLADFLASTQKMYGAELASVDFQQAPEDARKEINEWVKGQT 140

Query: 153 NGLITQLLPPGTVTNLTKLIFANALRFQGMWKHT-LDGLTHVSSFNLLSGTSVKVPYMTT 211
            G I +LL  G V N+TKL+  NA+ F+G W+   +   T  + F L    +  V  M  
Sbjct: 141 EGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQEKFMKEATRDAPFRLNKKDTKTVKMMYQ 200

Query: 212 FKKTQYVRAFD-GFKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQKLSSEPGFLK- 269
            KK  Y    D   ++L LPY QG++     SM I LPD  +  S  ++K+  +    K 
Sbjct: 201 KKKFPYNYIEDLKCRVLELPY-QGKE----LSMIILLPDDIEDESTGLEKIEKQLTLEKL 255

Query: 270 ---GKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSD 326
               K  +  +      +P+F +  +++ ++ L  +GV   F+   A  + M    S + 
Sbjct: 256 REWTKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQDLFNRGKADLSGM----SGAR 311

Query: 327 NLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSIDFIADHPFLFLIREDFTG 386
           +LFV  I HK+F+++NE+GT+A AAT   +         P  +F ADHPF+F IR + + 
Sbjct: 312 DLFVSKIIHKSFVDLNEEGTEAAAATAGTIMLAMLM---PEENFNADHPFIFFIRHNPSA 368

Query: 387 TILFVGQVLNP 397
            ILF+G+  +P
Sbjct: 369 NILFLGRFSSP 379


>NEUS_CHICK (Q90935) Neuroserpin precursor (Axonin-2)
          Length = 410

 Score =  142 bits (359), Expect = 1e-33
 Identities = 110/386 (28%), Positives = 194/386 (49%), Gaps = 48/386 (12%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTY-FSQGISPVFSDED 88
           +++N++F PLS+  A+ ++  G+ G TL E+   L FDS+ +   + F + +S + + E+
Sbjct: 42  EDENILFCPLSIAIAMGMIELGAHGTTLKEIRHSLGFDSLKNGEEFTFLKDLSDMATTEE 101

Query: 89  PASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLI 148
                S + L+  N +++     +S  F +L+  ++ A + ++DF+       H +N  +
Sbjct: 102 -----SHYVLNMANSLYVQNGFHVSEKFLQLVKKYFKAEVENIDFSQSAAVATH-INKWV 155

Query: 149 EQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTL-DGLTHVSSFNLLSGTSVKVP 207
           E  +N +I   +     + LT L+  NA+ F+G WK       T   SF     T V++P
Sbjct: 156 ENHTNNMIKDFVSSRDFSALTHLVLINAIYFKGNWKSQFRPENTRTFSFTKDDETEVQIP 215

Query: 208 YMTTFKKTQYVRAFDG-------FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQK 260
            M    +  Y    DG       +++L +PY+         SM I L   +  L  L   
Sbjct: 216 MMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE-----ISMMIVLSRQEVPLVTL--- 267

Query: 261 LSSEPGFLKGKLPH------RKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAH 314
              EP  +K  L +      +K +V  + +P+F +    +  +VLK +G+   FS     
Sbjct: 268 ---EP-LVKASLINEWANSVKKQKVEVY-LPRFTVEQEIDLKDVLKGLGITEVFS----- 317

Query: 315 FTKMVNVNSPSDN--LFVQSIFHKAFIEVNEKGTKATAATWS-ALARQCARDHHPSIDFI 371
             +  ++ + SDN  L++   FHKAF+EVNE+G++A AA+   A++R      +P +  I
Sbjct: 318 --RSADLTAMSDNKELYLAKAFHKAFLEVNEEGSEAAAASGMIAISRMAVL--YPQV--I 371

Query: 372 ADHPFLFLIREDFTGTILFVGQVLNP 397
            DHPF FL+R   TGT+LF+G+V++P
Sbjct: 372 VDHPFFFLVRNRRTGTVLFMGRVMHP 397


>SCC1_HUMAN (P29508) Squamous cell carcinoma antigen 1 (SCCA-1)
           (Protein T4-A)
          Length = 390

 Score =  140 bits (353), Expect = 6e-33
 Identities = 106/389 (27%), Positives = 178/389 (45%), Gaps = 42/389 (10%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNT-----YFSQGISPVF 84
           +E N+ +SP+S+ +AL ++  G++  T  ++   L FD +    T     Y       V 
Sbjct: 23  KENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVH 82

Query: 85  SDEDPA-----SSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDS 139
                       S   + L   N +F + T      +   +   Y  S+ S+DF    + 
Sbjct: 83  HQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEE 142

Query: 140 VLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLDGLTHVSSFNLL 199
               +NS +E ++N  I  L+P G + + T L+  NA+ F+G W+           FN  
Sbjct: 143 SRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWE---------KKFNKE 193

Query: 200 SGTSVKV-PYMTTFKKTQYVRAFDGF----------KILRLPYKQGRDRQRRFSMCIFLP 248
                K  P   T+K  Q +R +  F          K+L +PYK G+D     SM + LP
Sbjct: 194 DTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYK-GKD----LSMIVLLP 248

Query: 249 DAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPF 308
           +  DGL  L +KL++E       L + +       +P+F +  +++  + L+ +G+V  F
Sbjct: 249 NEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIF 308

Query: 309 SPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSI 368
           +  DA  + M      S  L +  + HKAF+EV E+G +A AAT  A+    +     + 
Sbjct: 309 NG-DADLSGMTG----SRGLVLSGVLHKAFVEVTEEGAEAAAAT--AVVGFGSSPTSTNE 361

Query: 369 DFIADHPFLFLIREDFTGTILFVGQVLNP 397
           +F  +HPFLF IR++ T +ILF G+  +P
Sbjct: 362 EFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>PTI6_MOUSE (Q60854) Placental thrombin inhibitor (Protease
           inhibitor 6) (PI-6)
          Length = 378

 Score =  140 bits (352), Expect = 8e-33
 Identities = 106/370 (28%), Positives = 172/370 (45%), Gaps = 20/370 (5%)

Query: 32  KNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSID-HLNTYFSQGISPVFSDEDPA 90
           KN+  SP+S+ +AL+++  G++G T  ++   L  D    +      QG   + ++ +  
Sbjct: 25  KNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGGDVHQGFQSLLTEVNKT 84

Query: 91  SSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLIEQ 150
            +  Q+ L   N +F D T  L   F+      Y A L  LDF    +     +N+ + +
Sbjct: 85  GT--QYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGATEESRQHINTWVAK 142

Query: 151 ESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLDGLTHVSSFNLLSGTSVKVPYMT 210
           ++   I ++L PGTV + T L+  NA+ F+G W+   +   H          + + P   
Sbjct: 143 KTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFN-KEHTREMPFKVSKNEEKPVQM 201

Query: 211 TFKKTQYVRAFDG---FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQKLSSEPGF 267
            FKK+ +   + G    KIL LPY          +M I LPD    LS + ++++ E   
Sbjct: 202 MFKKSTFKMTYIGEIFTKILLLPYVSS-----ELNMIIMLPDEHVELSTVEKEVTYEKFI 256

Query: 268 LKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSDN 327
              +L           +PKF +   +  ++ L ++G+   F    A F+ M    S    
Sbjct: 257 EWTRLDKMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAFGGR-ADFSGM----SSKQG 311

Query: 328 LFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSIDFIADHPFLFLIREDFTGT 387
           LF+  + HKAF+EVNE+GT+A AAT   +  +C R    +  F ADHPFLF I    T  
Sbjct: 312 LFLSKVVHKAFVEVNEEGTEAAAATAGMMTVRCMRF---TPRFCADHPFLFFIHHVKTNG 368

Query: 388 ILFVGQVLNP 397
           ILF G+  +P
Sbjct: 369 ILFCGRFSSP 378


>SPB9_HUMAN (P50453) Cytoplasmic antiproteinase 3 (CAP3) (CAP-3)
           (Protease inhibitor 9) (Serpin B9)
          Length = 376

 Score =  137 bits (344), Expect = 6e-32
 Identities = 97/374 (25%), Positives = 175/374 (45%), Gaps = 21/374 (5%)

Query: 27  EDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTYFSQGISPVFSD 86
           +D    N+  SP+S+ +AL+++  G++G T  ++   L  ++ + ++  F   ++ V   
Sbjct: 21  QDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEV--- 77

Query: 87  EDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNS 146
                + +Q+ L   N +F + T      F+      Y+A L  L F    +     +N+
Sbjct: 78  ---NKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINT 134

Query: 147 LIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLDGLTHVSSFNLLSGTSVKV 206
            + +++ G I +LLP  ++   T+L+  NA+ F+G W    D  T+            + 
Sbjct: 135 WVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE-TYTREMPFKINQEEQR 193

Query: 207 PYMTTFKKTQYVRAFDG---FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQKLSS 263
           P    +++  +  A  G    ++L LPY      ++  S+ + LPD    LS + + L+ 
Sbjct: 194 PVQMMYQEATFKLAHVGEVRAQLLELPY-----ARKELSLLVLLPDDGVELSTVEKSLTF 248

Query: 264 EPGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAHFTKMVNVNS 323
           E      K    K       +PKF +   ++  +VL+ +G+V  F    A  + M    S
Sbjct: 249 EKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAM----S 304

Query: 324 PSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDHHPSIDFIADHPFLFLIRED 383
              +L +    HK+F+EVNE+GT+A AA+   +  +C  +  P   F ADHPFLF IR +
Sbjct: 305 AERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPR--FCADHPFLFFIRHN 362

Query: 384 FTGTILFVGQVLNP 397
              +ILF G+  +P
Sbjct: 363 RANSILFCGRFSSP 376


>SPB8_HUMAN (P50452) Cytoplasmic antiproteinase 2 (CAP2) (CAP-2)
           (Protease inhibitor 8) (Serpin B8)
          Length = 374

 Score =  137 bits (344), Expect = 6e-32
 Identities = 106/393 (26%), Positives = 179/393 (44%), Gaps = 29/393 (7%)

Query: 11  CQSDVALSFTKHLFSKEDYQEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSID 70
           C+++   + +      E+   +N+ FSP+S+ +AL+++  G++G T  ++   L      
Sbjct: 5   CEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDG 64

Query: 71  HLNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLAS 130
            ++  F   +S V        + +Q+ L   N +F + T      F+      Y A L  
Sbjct: 65  DIHRGFQSLLSEV------NRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEE 118

Query: 131 LDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTLDGL 190
           L F    +     +N  + +++ G I+++L  GTV  LTKL+  NA+ F+G W    D  
Sbjct: 119 LSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFD-- 176

Query: 191 THVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDG---FKILRLPYKQGRDRQRRFSMCIFL 247
              +   L      K      FK+ ++   +      ++L LPY      +   SM I L
Sbjct: 177 RKYTRGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYV-----EEELSMVILL 231

Query: 248 PDAQDGLSALIQKLSSE---PGFLKGKLPHRKVRVRPFRVPKFNISFTFEASNVLKEVGV 304
           PD    L+ + + L+ E         KL   KV+V    +P+  +  +++    L+ +G+
Sbjct: 232 PDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQV---FLPRLKLEESYDLEPFLRRLGM 288

Query: 305 VSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWSALARQCARDH 364
           +  F    A F+ M    S   N+ +  + HK F+EVNE+GT+A AAT      +C+R  
Sbjct: 289 IDAFDEAKADFSGM----STEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR-- 342

Query: 365 HPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
                F ADHPFLF IR   T  ILF G+  +P
Sbjct: 343 -MEPRFCADHPFLFFIRRHKTNCILFCGRFSSP 374


>NEUS_HUMAN (Q99574) Neuroserpin precursor (Protease inhibitor 12)
          Length = 410

 Score =  136 bits (343), Expect = 8e-32
 Identities = 107/386 (27%), Positives = 194/386 (49%), Gaps = 48/386 (12%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTY-FSQGISPVFSDED 88
           +++N++FSPLS+  A+ +M  G++G T  E+   + +DS+ +   + F +  S + + ++
Sbjct: 42  EDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKE 101

Query: 89  PASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLI 148
                SQ+ +   N +F+     ++  F +++  ++NA++  +DF+ +  +V + +N  +
Sbjct: 102 -----SQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS-QNVAVANYINKWV 155

Query: 149 EQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTL-DGLTHVSSFNLLSGTSVKVP 207
           E  +N L+  L+ P      T L   NA+ F+G WK       T   SF     + V++P
Sbjct: 156 ENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIP 215

Query: 208 YMTTFKKTQYVRAFDG-------FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQK 260
            M    +  Y    DG       +++L +PY+         SM + L   +  L+ L   
Sbjct: 216 MMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE-----ISMMLVLSRQEVPLATL--- 267

Query: 261 LSSEPGFLKGKLPH------RKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAH 314
              EP  +K +L        +K +V  + +P+F +    +  +VLK +G+   F      
Sbjct: 268 ---EP-LVKAQLVEEWANSVKKQKVEVY-LPRFTVEQEIDLKDVLKALGITEIF------ 316

Query: 315 FTKMVNVNSPSDN--LFVQSIFHKAFIEVNEKGTKATAATWS-ALARQCARDHHPSIDFI 371
             K  N+   SDN  +F+    HK+F+EVNE+G++A A +   A++R      +P +  I
Sbjct: 317 -IKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVL--YPQV--I 371

Query: 372 ADHPFLFLIREDFTGTILFVGQVLNP 397
            DHPF FLIR   TGTILF+G+V++P
Sbjct: 372 VDHPFFFLIRNRRTGTILFMGRVMHP 397


>NEUS_MOUSE (O35684) Neuroserpin precursor (Protease inhibitor 17)
          Length = 410

 Score =  135 bits (341), Expect = 1e-31
 Identities = 109/384 (28%), Positives = 192/384 (49%), Gaps = 44/384 (11%)

Query: 30  QEKNLIFSPLSLYAALSVMAAGSEGRTLDELLSFLRFDSIDHLNTY-FSQGISPVFSDED 88
           +++N++FSPLS+  A+ +M  G++G T  E+   + ++ +     + F +  S + S E+
Sbjct: 42  EDENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEGLKGGEEFSFLRDFSNMASAEE 101

Query: 89  PASSPSQHHLSFTNGMFIDTTVSLSYPFRRLLSTHYNASLASLDFNLRGDSVLHDVNSLI 148
                +Q+ +   N +F+     ++  F ++L  ++NA +  +DF+ +  +V + +N  +
Sbjct: 102 -----NQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFS-QNVAVANSINKWV 155

Query: 149 EQESNGLITQLLPPGTVTNLTKLIFANALRFQGMWKHTL-DGLTHVSSFNLLSGTSVKVP 207
           E  +N L+  L+ P     +T L   NA+ F+G WK       T   SF     + V++P
Sbjct: 156 ENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIP 215

Query: 208 YMTTFKKTQYVRAFDG-------FKILRLPYKQGRDRQRRFSMCIFLPDAQDGLSALIQK 260
            M    +  Y    DG       +++L +PY+         SM + L   +  L+ L   
Sbjct: 216 MMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE-----ISMMLALSRQEVPLATL--- 267

Query: 261 LSSEPGFLKGKLPH------RKVRVRPFRVPKFNISFTFEASNVLKEVGVVSPFSPMDAH 314
              EP  LK +L        +K +V  + +P+F +    +  ++LK +GV   F   DA+
Sbjct: 268 ---EP-LLKAQLIEEWANSVKKQKVEVY-LPRFTVEQEIDLKDILKALGVTEIFIK-DAN 321

Query: 315 FTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWS-ALARQCARDHHPSIDFIAD 373
            T M    S    LF+    HK+ IEVNE+G++A AA+   A++R      +P +  I D
Sbjct: 322 LTAM----SDKKELFLSKAVHKSCIEVNEEGSEAAAASGMIAISRMAVL--YPQV--IVD 373

Query: 374 HPFLFLIREDFTGTILFVGQVLNP 397
           HPFL+LIR   +G ILF+G+V+NP
Sbjct: 374 HPFLYLIRNRKSGIILFMGRVMNP 397


>SB12_HUMAN (Q96P63) Serpin B12
          Length = 405

 Score =  133 bits (334), Expect = 9e-31
 Identities = 106/403 (26%), Positives = 184/403 (45%), Gaps = 50/403 (12%)

Query: 27  EDYQEKNLIFSPLSLYAALSVMAAGSEGRT---LDELLSFLRFDSIDH------------ 71
           +D + KN+ FSPLSL AAL ++  G+   +   +DE+L F  F   +             
Sbjct: 21  KDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPCLKSNKQ 80

Query: 72  -----------LNTYFSQGISPVFSDEDPASSPSQHHLSFTNGMFIDTTVSLSYPFRRLL 120
                      ++ YF Q +S +   +      + + LS  N ++ +    +   +   +
Sbjct: 81  KAGSLNNESGLVSCYFGQLLSKLDRIK------TDYTLSIANRLYGEQEFPICQEYLDGV 134

Query: 121 STHYNASLASLDFNLRGDSVLHDVNSLIEQESNGLITQLLPPGTVTNLTKLIFANALRFQ 180
              Y+ ++ S+DF    +    ++N  +E +S G I +L     +   T L+  NA+ F+
Sbjct: 135 IQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLVNAVYFK 194

Query: 181 GMWKHTLDGLTHVSSFNLLSGTSVKVPYMTTFKKTQYVRAFDGFK--ILRLPYKQGRDRQ 238
             W+   D    V +   L+    K   M T K    +   +  K  IL + Y +G+   
Sbjct: 195 AKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMRYTKGK--- 251

Query: 239 RRFSMCIFLP----DAQDGLSALIQKLSSEPGFLKGKLPHRKVRVRPFRVPKFNISFTFE 294
              SM + LP    D   GL  L +K++ E         +          P+F +  +++
Sbjct: 252 --LSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYD 309

Query: 295 ASNVLKEVGVVSPFSPMDAHFTKMVNVNSPSDNLFVQSIFHKAFIEVNEKGTKATAATWS 354
            +++L+++G+   F    A  T +    SPS NL++  I HK F+EV+E GT+A AAT +
Sbjct: 310 LNSILQDMGITDIFDETRADLTGI----SPSPNLYLSKIIHKTFVEVDENGTQAAAATGA 365

Query: 355 ALARQCARDHHPSIDFIADHPFLFLIREDFTGTILFVGQVLNP 397
            ++ +  R     ++F A+HPFLF IR + T TILF G+V +P
Sbjct: 366 VVSERSLRSW---VEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.322    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,847,680
Number of Sequences: 164201
Number of extensions: 1851983
Number of successful extensions: 4536
Number of sequences better than 10.0: 153
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 4017
Number of HSP's gapped (non-prelim): 169
length of query: 408
length of database: 59,974,054
effective HSP length: 113
effective length of query: 295
effective length of database: 41,419,341
effective search space: 12218705595
effective search space used: 12218705595
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)