BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0342b.11
         (137 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

NCS1_SCHPO (Q09711) Neuronal calcium sensor 1 (NCS-1)                  36  0.022
RRPL_TSWV1 (P28976) RNA-directed RNA polymerase (EC 2.7.7.48) (L...    34  0.11
KIP1_HUMAN (Q99828) Calcium and integrin-binding protein 1 (Calm...    33  0.14
KIP1_RAT (Q9R010) Calcium and integrin-binding protein 1 (Calmyr...    33  0.18
KDGG_HUMAN (P49619) Diacylglycerol kinase, gamma (EC 2.7.1.107) ...    33  0.18
KIP1_MOUSE (Q9Z0F4) Calcium and integrin-binding protein 1 (Calm...    33  0.24
HPCA_RAT (P84076) Neuron specific calcium-binding protein hippoc...    32  0.41
HPCA_MOUSE (P84075) Neuron specific calcium-binding protein hipp...    32  0.41
HPCA_HUMAN (P84074) Neuron specific calcium-binding protein hipp...    32  0.41
CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1      32  0.41
CSEN_RAT (Q9JM47) Calsenilin (DRE-antagonist modulator) (DREAM) ...    32  0.54
CSEN_MOUSE (Q9QXT8) Calsenilin (DRE-antagonist modulator) (DREAM...    32  0.54
S10A_RAT (P35467) S-100 protein, alpha chain                           31  0.70
NCB2_MOUSE (P81117) Nucleobindin 2 precursor (DNA-binding protei...    31  0.70
LPSA_LYTPI (P09485) Calcium-binding protein LPS1-alpha                 31  0.70
CSEN_HUMAN (Q9Y2W7) Calsenilin (DRE-antagonist modulator) (DREAM...    31  0.70
NCAD_POEGU (P62759) Neurocalcin delta                                  30  1.2
NCAD_CHICK (P62758) Neurocalcin delta                                  30  1.2
LPSB_LYTPI (Q03975) Calcium-binding protein LPS1-beta (Fragment)       30  1.2
EGLX_MOUSE (Q8BG58) Putative HIF-prolyl hydroxylase PH-4 (EC 1.1...    30  1.2

>NCS1_SCHPO (Q09711) Neuronal calcium sensor 1 (NCS-1)
          Length = 189

 Score = 36.2 bits (82), Expect = 0.022
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F L D + +GL+SY+EML+ +  +  +     + +  D D   +    +F   D N +G 
Sbjct: 104 FQLYDLDNNGLISYDEMLRIVDAIYKMVGSM-VKLPEDEDTPEKRVNKIFNMMDKNKDGQ 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LTLEEF 168


>RRPL_TSWV1 (P28976) RNA-directed RNA polymerase (EC 2.7.7.48) (L
           protein)
          Length = 2875

 Score = 33.9 bits (76), Expect = 0.11
 Identities = 24/105 (22%), Positives = 46/105 (42%), Gaps = 3/105 (2%)

Query: 6   LDGATIVNFLEDEEAFNISVCNRFALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKP 65
           L+  + +N L D+E   I+    +   +   D  + Y+E      CL + +    +D + 
Sbjct: 137 LNKKSCINKLSDDEFERIN--KEYVATNATPDNYVIYKESKNSELCLIIYDWKISVDART 194

Query: 66  DPDELGRVYKSLFIQF-DHNLNGSVDLEEFKMETREMMLAMADGM 109
           +  +    YK+++  F D  +NG   LEE  +    ++L    GM
Sbjct: 195 ETKQWRNTYKNIWKSFKDIKVNGKPFLEEHPVFVSIVILKPIAGM 239


>KIP1_HUMAN (Q99828) Calcium and integrin-binding protein 1
           (Calmyrin) (DNA-PKcs interacting protein) (Kinase
           interacting protein) (KIP) (CIB) (SNK interacting
           protein 2-28) (SIP2-28)
          Length = 190

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 21/94 (22%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 2   SVEILDGATIVNFLEDEEAFNISVCNRFALLDTNKDGLLSYEEMLKELQCLRVLETHFGI 61
           S+   D   +++   D    +I     F + D + DG L+ E++ + + CL    T  G 
Sbjct: 84  SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCL----TGEGE 139

Query: 62  DVKPDPDELGRVYKSLFIQFDHNLNGSVDLEEFK 95
           D +    E+ ++  ++  + D + +G+++L EF+
Sbjct: 140 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 173


>KIP1_RAT (Q9R010) Calcium and integrin-binding protein 1 (Calmyrin)
           (DNA-PKcs interacting protein) (Kinase interacting
           protein) (KIP) (CIB)
          Length = 190

 Score = 33.1 bits (74), Expect = 0.18
 Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 2   SVEILDGATIVNFLEDEEAFNISVCNRFALLDTNKDGLLSYEEMLKELQCLRVLETHFGI 61
           S+   D   +++   D    +I     F + D + DG L  E++ + + CL    T  G 
Sbjct: 84  SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLDREDLSRLVNCL----TGEGE 139

Query: 62  DVKPDPDELGRVYKSLFIQFDHNLNGSVDLEEFK 95
           D +    E+ ++  ++  + D + +G+++L EF+
Sbjct: 140 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 173


>KDGG_HUMAN (P49619) Diacylglycerol kinase, gamma (EC 2.7.1.107)
           (Diglyceride kinase) (DGK-gamma) (DAG kinase gamma)
          Length = 791

 Score = 33.1 bits (74), Expect = 0.18
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F L D++++GLL   EM     C+     H    ++ DP EL  + K +    D++ +G 
Sbjct: 184 FRLYDSDENGLLDQAEM----DCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGF 239

Query: 89  VDLEEF 94
           V L+E+
Sbjct: 240 VSLQEW 245


>KIP1_MOUSE (Q9Z0F4) Calcium and integrin-binding protein 1
           (Calmyrin) (DNA-PKcs interacting protein) (Kinase
           interacting protein) (KIP) (CIB)
          Length = 190

 Score = 32.7 bits (73), Expect = 0.24
 Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 2   SVEILDGATIVNFLEDEEAFNISVCNRFALLDTNKDGLLSYEEMLKELQCLRVLETHFGI 61
           S+   D   +++   D    +I     F + D + DG L  E++ + + CL    T  G 
Sbjct: 84  SLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLDREDLSQLVNCL----TGEGE 139

Query: 62  DVKPDPDELGRVYKSLFIQFDHNLNGSVDLEEFK 95
           D +    E+ ++  ++  + D + +G+++L EF+
Sbjct: 140 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 173


>HPCA_RAT (P84076) Neuron specific calcium-binding protein
           hippocalcin (P23K)
          Length = 192

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 19/66 (28%), Positives = 36/66 (53%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F++ D + +G +S EEML+ +Q +  + +   + +  D     +  + +F Q D N +G 
Sbjct: 104 FSMYDLDGNGYISREEMLEIVQAIYKMVSSV-MKMPEDESTPEKRTEKIFRQMDTNNDGK 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LSLEEF 168


>HPCA_MOUSE (P84075) Neuron specific calcium-binding protein
           hippocalcin
          Length = 192

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 19/66 (28%), Positives = 36/66 (53%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F++ D + +G +S EEML+ +Q +  + +   + +  D     +  + +F Q D N +G 
Sbjct: 104 FSMYDLDGNGYISREEMLEIVQAIYKMVSSV-MKMPEDESTPEKRTEKIFRQMDTNNDGK 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LSLEEF 168


>HPCA_HUMAN (P84074) Neuron specific calcium-binding protein
           hippocalcin (Calcium-binding protein BDR-2)
          Length = 192

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 19/66 (28%), Positives = 36/66 (53%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F++ D + +G +S EEML+ +Q +  + +   + +  D     +  + +F Q D N +G 
Sbjct: 104 FSMYDLDGNGYISREEMLEIVQAIYKMVSSV-MKMPEDESTPEKRTEKIFRQMDTNNDGK 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LSLEEF 168


>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1
          Length = 695

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 25/81 (30%), Positives = 36/81 (43%), Gaps = 16/81 (19%)

Query: 15  LEDEEAFNISVCNRFA-LLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRV 73
           L  E AFN       A + DT+KDGL+S+ E           +   G+   PD      +
Sbjct: 65  LFSESAFNDESVRLLANIADTSKDGLISFSE----------FQAFEGLLCTPD-----AL 109

Query: 74  YKSLFIQFDHNLNGSVDLEEF 94
           Y++ F  FD   NG+V   +F
Sbjct: 110 YRTAFQLFDRKGNGTVSYADF 130


>CSEN_RAT (Q9JM47) Calsenilin (DRE-antagonist modulator) (DREAM) (Kv
           channel-interacting protein 3) (A-type potassium channel
           modulatory protein 3) (KChIP3)
          Length = 256

 Score = 31.6 bits (70), Expect = 0.54
 Identities = 20/66 (30%), Positives = 33/66 (49%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F L D NKDG ++ EEML  ++ +  +       +  +   L  V +  F + D N +G 
Sbjct: 171 FNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFFQKMDRNQDGV 229

Query: 89  VDLEEF 94
           V ++EF
Sbjct: 230 VTIDEF 235


>CSEN_MOUSE (Q9QXT8) Calsenilin (DRE-antagonist modulator) (DREAM)
           (Kv channel-interacting protein 3) (A-type potassium
           channel modulatory protein 3) (KChIP3)
          Length = 256

 Score = 31.6 bits (70), Expect = 0.54
 Identities = 20/66 (30%), Positives = 33/66 (49%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F L D NKDG ++ EEML  ++ +  +       +  +   L  V +  F + D N +G 
Sbjct: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFFQKMDRNQDGV 229

Query: 89  VDLEEF 94
           V ++EF
Sbjct: 230 VTIDEF 235


>S10A_RAT (P35467) S-100 protein, alpha chain
          Length = 93

 Score = 31.2 bits (69), Expect = 0.70
 Identities = 19/53 (35%), Positives = 28/53 (51%), Gaps = 4/53 (7%)

Query: 42 YEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGSVDLEEF 94
          Y+   KEL+ L   E    +DV+ D D + ++ K L    D N +G VD +EF
Sbjct: 26 YKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKEL----DENGDGEVDFQEF 74


>NCB2_MOUSE (P81117) Nucleobindin 2 precursor (DNA-binding protein
           NEFA)
          Length = 420

 Score = 31.2 bits (69), Expect = 0.70
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 7/100 (7%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDP-----DELGRVYKSLFIQFDH 83
           F L D N DG L  +E+  E    R LE  +      D      +E  R+ + +  + D+
Sbjct: 250 FKLHDVNNDGFLDEQEL--EALFTRELEKVYNPQNAEDDMIEMEEERLRMREHVMSEIDN 307

Query: 84  NLNGSVDLEEFKMETREMMLAMADGMGFLPVQMALEEDSI 123
           N +  V LEEF   T +      D    L  Q    ED +
Sbjct: 308 NKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDEL 347


>LPSA_LYTPI (P09485) Calcium-binding protein LPS1-alpha
          Length = 321

 Score = 31.2 bits (69), Expect = 0.70
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 20/105 (19%)

Query: 33  DTNKDGLLSYEEMLKELQCLRVLETHF--GIDVKPDP----DEL---------GRVY--- 74
           DTNKDG +S  E++K +     +  +    +DV  D     DE           R+Y   
Sbjct: 29  DTNKDGTVSCAELVKLMNWTEEMAQNIIARLDVNSDGHMQFDEFILYMEGSTKERLYSSD 88

Query: 75  --KSLFIQFDHNLNGSVDLEEFKMETREMMLAMADGMGFLPVQMA 117
             K +F   D + NG +  +E     RE+   + DGM    +Q A
Sbjct: 89  EIKQMFDDLDKDGNGRISPDELNKGVREIYTKVVDGMANKLIQEA 133


>CSEN_HUMAN (Q9Y2W7) Calsenilin (DRE-antagonist modulator) (DREAM)
           (Kv channel-interacting protein 3) (A-type potassium
           channel modulatory protein 3) (KChIP3)
          Length = 256

 Score = 31.2 bits (69), Expect = 0.70
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F L D NKDG ++ EEML  ++ +  +       +  + D      +  F + D N +G 
Sbjct: 171 FNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILRE-DAPAEHVERFFEKMDRNQDGV 229

Query: 89  VDLEEF 94
           V +EEF
Sbjct: 230 VTIEEF 235


>NCAD_POEGU (P62759) Neurocalcin delta
          Length = 192

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 18/66 (27%), Positives = 35/66 (52%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F++ D + +G +S  EML+ +Q +  + +   + +  D     +  + +F Q D N +G 
Sbjct: 104 FSMYDLDGNGYISKSEMLEIVQAIYKMVSSV-MKMPEDESTPEKRTEKIFRQMDTNRDGK 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LSLEEF 168


>NCAD_CHICK (P62758) Neurocalcin delta
          Length = 192

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 18/66 (27%), Positives = 35/66 (52%), Gaps = 1/66 (1%)

Query: 29  FALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYKSLFIQFDHNLNGS 88
           F++ D + +G +S  EML+ +Q +  + +   + +  D     +  + +F Q D N +G 
Sbjct: 104 FSMYDLDGNGYISKSEMLEIVQAIYKMVSSV-MKMPEDESTPEKRTEKIFRQMDTNRDGK 162

Query: 89  VDLEEF 94
           + LEEF
Sbjct: 163 LSLEEF 168


>LPSB_LYTPI (Q03975) Calcium-binding protein LPS1-beta (Fragment)
          Length = 243

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 30/108 (27%), Positives = 45/108 (40%), Gaps = 26/108 (24%)

Query: 33  DTNKDGLLSYEEMLKELQC-----LRVLETHFGIDVKPDP----DEL---------GRVY 74
           DTNKDG +S  E+ K + C      R++    G+DV  D     DE           R+Y
Sbjct: 29  DTNKDGTVSCAELAKLMDCPEEEAQRIIT---GVDVNCDGRMQFDEFLLYMEGYTKERLY 85

Query: 75  -----KSLFIQFDHNLNGSVDLEEFKMETREMMLAMADGMGFLPVQMA 117
                K +F   D + NG +  +E      E+   + +GM    +Q A
Sbjct: 86  SSDEIKQMFDDLDKDGNGRISPDELSKGVGEISTKLVEGMANKLIQEA 133


>EGLX_MOUSE (Q8BG58) Putative HIF-prolyl hydroxylase PH-4 (EC
           1.14.11.-) (Hypoxia-inducible factor prolyl
           4-hydroxylase)
          Length = 503

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 16  EDEEAFNISVCNRFALLDTNKDGLLSYEEMLKELQCLRVLETHFGIDVKPDPDELGRVYK 75
           E   A  +S  + F LLD N DG L   E+L         +T  G      P+ +  +Y 
Sbjct: 182 EAMSAMQVSQLDLFQLLDQNHDGRLQLREVL--------AQTRLGNGRWMTPENIQEMYS 233

Query: 76  SLFIQFDHNLNGSVDLEEF-KMETRE 100
           +  I+ D + +G + L+EF  M+ R+
Sbjct: 234 A--IKADPDGDGVLSLQEFSNMDLRD 257


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.321    0.139    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,817,958
Number of Sequences: 164201
Number of extensions: 625963
Number of successful extensions: 2026
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1966
Number of HSP's gapped (non-prelim): 128
length of query: 137
length of database: 59,974,054
effective HSP length: 98
effective length of query: 39
effective length of database: 43,882,356
effective search space: 1711411884
effective search space used: 1711411884
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)