BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0334a.8
         (635 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

MAOX_PHAVU (P12628) NADP-dependent malic enzyme (EC 1.1.1.40) (N...  1053  0.0
MAOX_VITVI (P51615) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   974  0.0
MAOC_FLAPR (P36444) NADP-dependent malic enzyme, chloroplast pre...   972  0.0
MAOX_POPTR (P34105) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   957  0.0
MAOC_ORYSA (P43279) NADP-dependent malic enzyme, chloroplast pre...   942  0.0
MAOC_FLATR (P22178) NADP-dependent malic enzyme, chloroplast pre...   936  0.0
MAOX_MESCR (P37223) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   935  0.0
MAOC_LYCES (P37222) NADP-dependent malic enzyme, chloroplast (EC...   929  0.0
MAOC_MAIZE (P16243) NADP-dependent malic enzyme, chloroplast pre...   889  0.0
MAOX_ANAPL (P28227) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   576  e-164
MAOX_COLLI (P40927) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   571  e-162
MAOX_RAT (P13697) NADP-dependent malic enzyme (EC 1.1.1.40) (NAD...   565  e-160
MAOX_MOUSE (P06801) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   561  e-159
MAOX_HUMAN (P48163) NADP-dependent malic enzyme (EC 1.1.1.40) (N...   558  e-158
MAON_HUMAN (Q16798) NADP-dependent malic enzyme, mitochondrial p...   556  e-158
MAOX_PIG (Q29558) NADP-dependent malic enzyme (EC 1.1.1.40) (NAD...   555  e-157
MAOM_HUMAN (P23368) NAD-dependent malic enzyme, mitochondrial pr...   554  e-157
MAOM_MOUSE (Q99KE1) NAD-dependent malic enzyme, mitochondrial pr...   551  e-156
MAOM_ASCSU (P27443) NAD-dependent malic enzyme, mitochondrial pr...   523  e-148
MAO1_ECOLI (P26616) NAD-dependent malic enzyme (EC 1.1.1.38) (NA...   436  e-122

>MAOX_PHAVU (P12628) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 589

 Score = 1053 bits (2722), Expect = 0.0
 Identities = 523/587 (89%), Positives = 555/587 (94%), Gaps = 3/587 (0%)

Query: 48  AMSRNGGEGVVGEDFKNSEESGGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNK 107
           ++  NGGE  V +D+ N    GGVRDLYGEDSATED LITPWTFSVASG +LLRDPRYNK
Sbjct: 5   SLKENGGEVSVKKDYSNG---GGVRDLYGEDSATEDHLITPWTFSVASGCSLLRDPRYNK 61

Query: 108 GLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLF 167
           GLAFTE ERDAHYLRGLLPP+VF QELQEKR MHN+RQYEVPLH+YMA+MDLQERNERLF
Sbjct: 62  GLAFTEGERDAHYLRGLLPPSVFNQELQEKRLMHNLRQYEVPLHRYMALMDLQERNERLF 121

Query: 168 YKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQ 227
           YK+LIDNV ELLP+VYTP VGEACQKYGSI++RPQGLYISLKEKGKILEVLKNWPEK+IQ
Sbjct: 122 YKLLIDNVAELLPVVYTPTVGEACQKYGSIFRRPQGLYISLKEKGKILEVLKNWPEKSIQ 181

Query: 228 VIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDE 287
           VIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNE LLNDE
Sbjct: 182 VIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNEKLLNDE 241

Query: 288 FYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVF 347
           FY GLRQ+RATG+EY   LDEFMRAVKQNYGEKVL+QFEDFANHNAF+LL++YSSSHLVF
Sbjct: 242 FYIGLRQRRATGQEYATFLDEFMRAVKQNYGEKVLVQFEDFANHNAFDLLEKYSSSHLVF 301

Query: 348 NDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVE 407
           NDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA+E+SKQTKAPVE
Sbjct: 302 NDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIAVEVSKQTKAPVE 361

Query: 408 ETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGK 467
           ETRKK+WLVDSKGLIV SRLESLQ FKKPWAHEHEPVK LL+AVKAIKPTVLIGSSG GK
Sbjct: 362 ETRKKIWLVDSKGLIVSSRLESLQQFKKPWAHEHEPVKGLLEAVKAIKPTVLIGSSGAGK 421

Query: 468 TFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGK 527
           TFTKEVVE MASLNEKPLILALSNPTSQSECTAEEAYTWSKG+AIFASGSPFDPV+Y GK
Sbjct: 422 TFTKEVVETMASLNEKPLILALSNPTSQSECTAEEAYTWSKGRAIFASGSPFDPVEYEGK 481

Query: 528 VYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTN 587
           ++ PGQANNAYIFPGFGLGLI+SGAIRVRDEMLLAASEALAAQVS+ENYDKGLIYPPFTN
Sbjct: 482 LFVPGQANNAYIFPGFGLGLIMSGAIRVRDEMLLAASEALAAQVSEENYDKGLIYPPFTN 541

Query: 588 IRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           IRKISA+IAA VAAK Y+LGLASHL RPKDLVKYAESCMYSPGYRSY
Sbjct: 542 IRKISANIAAKVAAKAYDLGLASHLKRPKDLVKYAESCMYSPGYRSY 588


>MAOX_VITVI (P51615) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 591

 Score =  974 bits (2517), Expect = 0.0
 Identities = 476/566 (84%), Positives = 525/566 (92%)

Query: 69  GGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPA 128
           GGV DLYGED ATEDQL+TPWT SVASG +LLRDPR+NKGLAF +KERDAHYL GLLPP 
Sbjct: 25  GGVEDLYGEDFATEDQLVTPWTVSVASGYSLLRDPRHNKGLAFNDKERDAHYLCGLLPPV 84

Query: 129 VFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILIDNVEELLPIVYTPVVG 188
           V TQELQE++ M++IRQY+VPL KYMAMMDLQERNERLFYK+LIDNVEELLP+VYTP VG
Sbjct: 85  VSTQELQERKLMNSIRQYQVPLQKYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVG 144

Query: 189 EACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTDGERILGLGDLGCQGM 248
           EACQKYGSI++RPQGLYISLKEKGKILEVLKNWPE+ IQVIVVTDGERILGLGDLGCQGM
Sbjct: 145 EACQKYGSIFRRPQGLYISLKEKGKILEVLKNWPERRIQVIVVTDGERILGLGDLGCQGM 204

Query: 249 GIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGLRQKRATGKEYEELLDE 308
           GIPVGKLSLYTALGGVRPS+CLP+TIDVGTNNE LL +EFY GL+Q+RATGKEY E L E
Sbjct: 205 GIPVGKLSLYTALGGVRPSACLPITIDVGTNNEKLLANEFYIGLKQRRATGKEYSEFLQE 264

Query: 309 FMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQGTASVVLAGLLASLKL 368
           FM  VKQNYGEKVLIQFEDFANHNAF+LL +Y ++HL FNDDIQGTASVVLAG++++L+L
Sbjct: 265 FMSPVKQNYGEKVLIQFEDFANHNAFDLLAKYGTTHLAFNDDIQGTASVVLAGIVSALRL 324

Query: 369 VGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKKVWLVDSKGLIVRSRLE 428
           +GGTLADH FLFLGAGEAGTGIAELIALE+SKQTK P+EETRKK+WLVDSKGLIV SR +
Sbjct: 325 LGGTLADHKFLFLGAGEAGTGIAELIALEMSKQTKCPIEETRKKIWLVDSKGLIVGSRKD 384

Query: 429 SLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILA 488
           SLQ FKKPWAHEHEPVK LLDAVK IKPTVLIGSSGVGK FTKEV+EAMAS NEKPLILA
Sbjct: 385 SLQQFKKPWAHEHEPVKDLLDAVKVIKPTVLIGSSGVGKAFTKEVIEAMASCNEKPLILA 444

Query: 489 LSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFGLGLI 548
           LSNPTSQSECTAEEAYTW++G+AIFASGSPFDPV+Y GK + PGQANNAYIFPG G+GL+
Sbjct: 445 LSNPTSQSECTAEEAYTWTQGRAIFASGSPFDPVEYNGKTFVPGQANNAYIFPGLGMGLV 504

Query: 549 ISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGL 608
           ISGAIRV DEMLLAASEALA QV+QEN+DKGLIYPPF+NIRKISAHIAA+VAAK YELGL
Sbjct: 505 ISGAIRVHDEMLLAASEALARQVTQENFDKGLIYPPFSNIRKISAHIAANVAAKAYELGL 564

Query: 609 ASHLPRPKDLVKYAESCMYSPGYRSY 634
           A+ LP+P++LVKYAESCMYSP YRSY
Sbjct: 565 ATRLPQPENLVKYAESCMYSPVYRSY 590


>MAOC_FLAPR (P36444) NADP-dependent malic enzyme, chloroplast
           precursor (EC 1.1.1.40) (NADP-ME)
          Length = 647

 Score =  973 bits (2514), Expect = 0.0
 Identities = 472/566 (83%), Positives = 524/566 (92%)

Query: 69  GGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPA 128
           GGV D+YGEDSATED  ITPW+ SVASG +LLRDP +NKGLAFTEKERDAHYLRGLLPP 
Sbjct: 81  GGVEDVYGEDSATEDHFITPWSVSVASGYSLLRDPHHNKGLAFTEKERDAHYLRGLLPPV 140

Query: 129 VFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILIDNVEELLPIVYTPVVG 188
           V   +LQ K+ MHNIRQYEVPL +Y AMMDLQERNERLFYK+LI+N+EELLPIVYTP VG
Sbjct: 141 VVNHDLQVKKMMHNIRQYEVPLQRYQAMMDLQERNERLFYKLLIENIEELLPIVYTPTVG 200

Query: 189 EACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTDGERILGLGDLGCQGM 248
           EACQKYG+I+K PQGLYISLK+KGK+LE+LKNWP+K IQVIVVTDGERILGLGDLGCQGM
Sbjct: 201 EACQKYGTIFKNPQGLYISLKDKGKVLEILKNWPQKKIQVIVVTDGERILGLGDLGCQGM 260

Query: 249 GIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGLRQKRATGKEYEELLDE 308
           GIPVGKLSLYTALGG+RPS+CLP+TIDVGTNNE +LNDEFY GLRQ+RA+GKEY EL++E
Sbjct: 261 GIPVGKLSLYTALGGIRPSACLPITIDVGTNNEKMLNDEFYIGLRQRRASGKEYAELMNE 320

Query: 309 FMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQGTASVVLAGLLASLKL 368
           FM AVKQNYGEKVLIQFEDFANHNAF+LL++Y ++HLVFNDDIQGTASVVLAGL+++LKL
Sbjct: 321 FMSAVKQNYGEKVLIQFEDFANHNAFDLLEKYRTTHLVFNDDIQGTASVVLAGLISALKL 380

Query: 369 VGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKKVWLVDSKGLIVRSRLE 428
           VGG+LADH FLFLGAGEAGTGIAELIALEISKQT AP+EETRKK+WLVDSKGLIVRSRL+
Sbjct: 381 VGGSLADHKFLFLGAGEAGTGIAELIALEISKQTNAPLEETRKKIWLVDSKGLIVRSRLD 440

Query: 429 SLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILA 488
           SLQHFKKPWAH+HEPV   LDAVKAIKPTVLIGSSG G+TFTKEVVEAM+S NEKP+ILA
Sbjct: 441 SLQHFKKPWAHDHEPVNKFLDAVKAIKPTVLIGSSGAGQTFTKEVVEAMSSFNEKPIILA 500

Query: 489 LSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFGLGLI 548
           LSNPTSQSECTAE+AYTWS+G+ IFASGSPF PV+Y GKVY  GQ+NNAYIFPGFGLGLI
Sbjct: 501 LSNPTSQSECTAEQAYTWSEGRTIFASGSPFAPVEYNGKVYVSGQSNNAYIFPGFGLGLI 560

Query: 549 ISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGL 608
           ISGAIRV DEMLLAASEALA QV+QE++D GLIYPPFTNIRKISAHIAA VAAK YELGL
Sbjct: 561 ISGAIRVHDEMLLAASEALAEQVTQEHFDNGLIYPPFTNIRKISAHIAAKVAAKAYELGL 620

Query: 609 ASHLPRPKDLVKYAESCMYSPGYRSY 634
           AS LP+P++LV YAESCMYSP YR+Y
Sbjct: 621 ASRLPQPENLVAYAESCMYSPKYRNY 646


>MAOX_POPTR (P34105) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 591

 Score =  957 bits (2475), Expect = 0.0
 Identities = 469/581 (80%), Positives = 527/581 (89%), Gaps = 1/581 (0%)

Query: 54  GEGVVGEDFKNSEESGGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTE 113
           G  V+  D K S   GGV D+YGED ATEDQL+TPWT SVASG TLLRDP +NKGLAFTE
Sbjct: 11  GASVLDMDPK-STVGGGVEDVYGEDRATEDQLVTPWTISVASGYTLLRDPHHNKGLAFTE 69

Query: 114 KERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILID 173
           KERDAHYLRGLLPP   +Q+LQEK+ M+ IRQY++PL KY AMM+L+ERNERLFYK+LID
Sbjct: 70  KERDAHYLRGLLPPTTISQQLQEKKLMNTIRQYQLPLQKYTAMMELEERNERLFYKLLID 129

Query: 174 NVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTD 233
           NVEELLP+VYTP VGEACQKYGSI+KRPQGLYISLKEKGK+L+VLKNWP+K+IQVIVVTD
Sbjct: 130 NVEELLPVVYTPTVGEACQKYGSIFKRPQGLYISLKEKGKVLDVLKNWPQKSIQVIVVTD 189

Query: 234 GERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGLR 293
           GERILGLGDLGCQG+GIPVGKLSLYTALGGVRPS+CLPVTIDVGTNNE LL DEFY GLR
Sbjct: 190 GERILGLGDLGCQGIGIPVGKLSLYTALGGVRPSACLPVTIDVGTNNEQLLKDEFYIGLR 249

Query: 294 QKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQG 353
           Q+RATG+EY ELL EFM AVKQNYGEKVLIQFEDFANHNAF+LL +Y ++HLVFNDDIQG
Sbjct: 250 QRRATGQEYSELLHEFMTAVKQNYGEKVLIQFEDFANHNAFDLLAKYGTTHLVFNDDIQG 309

Query: 354 TASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKKV 413
           TA+VVLAGL+++LKL+GG+LADHTFLFLGAGEAGTGIAELIALE+S+++K P+EETRKK+
Sbjct: 310 TAAVVLAGLISALKLLGGSLADHTFLFLGAGEAGTGIAELIALEMSRRSKTPLEETRKKI 369

Query: 414 WLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEV 473
           WL DSKGLIV SR ESLQHFKKPWAHEHEPVK LL+ VKAIKP VLIG+SGVGKTFTKEV
Sbjct: 370 WLTDSKGLIVSSRKESLQHFKKPWAHEHEPVKGLLEVVKAIKPIVLIGTSGVGKTFTKEV 429

Query: 474 VEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQ 533
           +EAMAS NEKPLILALSNPTSQSECTA+EAYTW+KGKAIFASGSPFDPV+Y GKV+ PGQ
Sbjct: 430 IEAMASFNEKPLILALSNPTSQSECTAQEAYTWTKGKAIFASGSPFDPVEYEGKVFVPGQ 489

Query: 534 ANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKISA 593
           +NNAYIFPG GLGL+ISGAIRV D+MLLAA+EALA Q+ +E   KGLIYPP +NIRKIS 
Sbjct: 490 SNNAYIFPGLGLGLVISGAIRVHDDMLLAAAEALAGQIKEEYLAKGLIYPPLSNIRKISV 549

Query: 594 HIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
            IAA+VAAK YELGLA+ LPRP++LVK+AESCMYSP YR Y
Sbjct: 550 QIAANVAAKAYELGLATRLPRPENLVKHAESCMYSPAYRYY 590


>MAOC_ORYSA (P43279) NADP-dependent malic enzyme, chloroplast
           precursor (EC 1.1.1.40) (NADP-ME)
          Length = 638

 Score =  942 bits (2436), Expect = 0.0
 Identities = 460/582 (79%), Positives = 524/582 (89%), Gaps = 2/582 (0%)

Query: 55  EGVVGEDFKNSEESGGVRDLYG--EDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFT 112
           E V  E    +E+   V    G  ED ATE+  +TPW FSVASG TLLRDP +NKGLAF+
Sbjct: 56  EAVAMESAAETEKKEEVAAAGGGVEDMATEEVPVTPWAFSVASGYTLLRDPHHNKGLAFS 115

Query: 113 EKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILI 172
           EKERDAHYLRGLLPPAV +Q+LQ K+ MHN+RQY VPL +YMAMMDLQERNERLFYK+LI
Sbjct: 116 EKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPLQRYMAMMDLQERNERLFYKLLI 175

Query: 173 DNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVT 232
           DNVEELLP+VYTP VGEACQKYGSI+++PQGLY+SLK+KGK+L+VL+NWPE+ IQVIVVT
Sbjct: 176 DNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDVLRNWPERNIQVIVVT 235

Query: 233 DGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGL 292
           DGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPS+CLP+TIDVGTNNE LLNDEFY GL
Sbjct: 236 DGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGL 295

Query: 293 RQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQ 352
           RQ+RATGKEY EL++EFM AVKQ YGEKVLIQFEDFANHNAF+LL +YS SHLVFNDDIQ
Sbjct: 296 RQRRATGKEYHELMEEFMSAVKQIYGEKVLIQFEDFANHNAFDLLAKYSKSHLVFNDDIQ 355

Query: 353 GTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKK 412
           GTASVVLAGLL+SLK+VGGTLA+HT+LFLGAGEAGTGIAELIALEISKQTKAP+EE RKK
Sbjct: 356 GTASVVLAGLLSSLKVVGGTLAEHTYLFLGAGEAGTGIAELIALEISKQTKAPIEECRKK 415

Query: 413 VWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKE 472
           VWL+DSKGLIV SR ESLQ FKKPWAHEHEPV  LLDAV++IKPTVLIG+SGVGKTFTKE
Sbjct: 416 VWLLDSKGLIVNSRKESLQAFKKPWAHEHEPVTTLLDAVQSIKPTVLIGTSGVGKTFTKE 475

Query: 473 VVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPG 532
           V+EAMAS NE+P+I +L+NPTS SECTAEEAY WS+G+A+FASGSPFDPV+Y GK++ PG
Sbjct: 476 VIEAMASFNERPVIFSLANPTSHSECTAEEAYNWSQGRAVFASGSPFDPVEYNGKIHVPG 535

Query: 533 QANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKIS 592
           Q+NNAYIFPGFGLG++ISGA+RV ++MLLAASE LA Q +QEN++KG I+PPFTNIRKIS
Sbjct: 536 QSNNAYIFPGFGLGVVISGAVRVHEDMLLAASETLADQATQENFEKGSIFPPFTNIRKIS 595

Query: 593 AHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           A IAA+VAAK YELGLA+ LP+P+DL KYAESCMY+P YRSY
Sbjct: 596 ARIAATVAAKAYELGLATRLPQPRDLEKYAESCMYTPVYRSY 637


>MAOC_FLATR (P22178) NADP-dependent malic enzyme, chloroplast
           precursor (EC 1.1.1.40) (NADP-ME)
          Length = 648

 Score =  936 bits (2420), Expect = 0.0
 Identities = 457/567 (80%), Positives = 516/567 (90%), Gaps = 1/567 (0%)

Query: 69  GGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPA 128
           GGV D+YGED+ATED  ITPW+ SVASG +LLRDP +NKGLAFTEKERDAH+LRGLLPP 
Sbjct: 81  GGVEDMYGEDTATEDHYITPWSVSVASGYSLLRDPHHNKGLAFTEKERDAHFLRGLLPPV 140

Query: 129 VFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILIDNVEELLPIVYTPVVG 188
           V   +LQ K+ MHNIRQY+VPL +Y AMMDLQ+RNERLFYK+LI+NVEELLPIVYTP VG
Sbjct: 141 VVNHDLQVKKMMHNIRQYQVPLQRYQAMMDLQQRNERLFYKLLIENVEELLPIVYTPTVG 200

Query: 189 EACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTDGERILGLGDLGCQGM 248
           EACQKYGSI++  QGL+ISLK+KG+ILE+LKNWP K IQVIVVTDGERILGLGDLGCQGM
Sbjct: 201 EACQKYGSIFENSQGLFISLKDKGRILEILKNWPHKKIQVIVVTDGERILGLGDLGCQGM 260

Query: 249 GIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLND-EFYTGLRQKRATGKEYEELLD 307
           GIPVGKL+LYTALGGVRPS+CLP+TIDVGTNNE LLND EFY GL+QKRA G+EY EL++
Sbjct: 261 GIPVGKLALYTALGGVRPSACLPITIDVGTNNEKLLNDDEFYIGLKQKRAAGQEYAELMN 320

Query: 308 EFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQGTASVVLAGLLASLK 367
           EFM AVKQNYGE +LIQFEDFANHNAF+LL++Y ++HLVFNDDIQGTASVVL GL+++LK
Sbjct: 321 EFMSAVKQNYGENLLIQFEDFANHNAFDLLEKYRTTHLVFNDDIQGTASVVLGGLISALK 380

Query: 368 LVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKKVWLVDSKGLIVRSRL 427
           LVGG+LAD  FLFLGAGEAGTGIAELIALEISKQT  P+EE+RKKVWLVDSKGLIVRSRL
Sbjct: 381 LVGGSLADQKFLFLGAGEAGTGIAELIALEISKQTNIPLEESRKKVWLVDSKGLIVRSRL 440

Query: 428 ESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLIL 487
           +SLQHFKKPWAH+HEPV   LDA+K I+PTVLIGSSG G+TFTKEVVE M+SLNEKP+IL
Sbjct: 441 DSLQHFKKPWAHDHEPVNEFLDAIKTIRPTVLIGSSGTGQTFTKEVVETMSSLNEKPIIL 500

Query: 488 ALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFGLGL 547
           ALSNPTSQSECTAE+AYTWS+G+AIFASGSPF PV+Y GK+Y  GQANNAYIFPGFGLGL
Sbjct: 501 ALSNPTSQSECTAEQAYTWSEGRAIFASGSPFKPVEYNGKLYVSGQANNAYIFPGFGLGL 560

Query: 548 IISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVYELG 607
           IISGAIRV D+MLLAASEA A QV+QE++DKGLI+PPFT+IRKISAHIAA VAAK YELG
Sbjct: 561 IISGAIRVHDDMLLAASEAPAEQVTQEHFDKGLIFPPFTSIRKISAHIAAKVAAKAYELG 620

Query: 608 LASHLPRPKDLVKYAESCMYSPGYRSY 634
           LAS LP+P++LV YAESCMYSP YR Y
Sbjct: 621 LASRLPQPENLVAYAESCMYSPKYRIY 647


>MAOX_MESCR (P37223) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 585

 Score =  935 bits (2417), Expect = 0.0
 Identities = 453/583 (77%), Positives = 527/583 (89%), Gaps = 1/583 (0%)

Query: 53  GGEGVVGEDFKNSEE-SGGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAF 111
           GG   + E    S+  +GGV D+YGE+ AT+DQL+TPW+FSVA G++LLRDP++NKGLAF
Sbjct: 2   GGSNALNEMTNGSDGITGGVADVYGEEFATQDQLVTPWSFSVACGHSLLRDPQHNKGLAF 61

Query: 112 TEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKIL 171
           TEKERDAH+LRGLLPP V +QELQEK+ +  +RQY+VPL KYMAMMDLQERNE+LFYK+L
Sbjct: 62  TEKERDAHFLRGLLPPVVLSQELQEKKFLTTLRQYQVPLQKYMAMMDLQERNEKLFYKLL 121

Query: 172 IDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVV 231
           +D+VEELLP+VYTP VGE CQKYGSI++RPQGL+ISLK+KG+ILE+L+NWPEK IQVIVV
Sbjct: 122 VDHVEELLPLVYTPTVGEGCQKYGSIFRRPQGLFISLKDKGRILELLRNWPEKKIQVIVV 181

Query: 232 TDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTG 291
           TDGERILGLGDLGCQGMGIPVGKLSLY+ALGGV PS+CLP+T+DVGTNN+ LL+DEFY G
Sbjct: 182 TDGERILGLGDLGCQGMGIPVGKLSLYSALGGVCPSACLPITLDVGTNNQKLLDDEFYIG 241

Query: 292 LRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDI 351
           L+QKRATG+EY E + EFM AVKQNYGEK+L+QFEDFANHNAF LL++Y ++HLVFNDDI
Sbjct: 242 LKQKRATGEEYAEFVQEFMSAVKQNYGEKILVQFEDFANHNAFELLEKYRTTHLVFNDDI 301

Query: 352 QGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRK 411
           QGTASVVLAGL+ASLKL+GGTLADH FLFLGAGEAGTGIAELIALE+SK+TKAPVE+ RK
Sbjct: 302 QGTASVVLAGLIASLKLLGGTLADHKFLFLGAGEAGTGIAELIALEMSKKTKAPVEQMRK 361

Query: 412 KVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTK 471
           K+WLVDSKGL+V SR E+LQ FK PWAHEHEP+  L+DAV+AIKPTVLIG+SG GK FTK
Sbjct: 362 KIWLVDSKGLVVSSRKETLQQFKLPWAHEHEPITTLIDAVQAIKPTVLIGTSGKGKQFTK 421

Query: 472 EVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAP 531
           EVVEAMA++N KPLILALSNPTSQSECTAEEAYTWS+G AIFASGSPFDPV+Y G+ + P
Sbjct: 422 EVVEAMANINAKPLILALSNPTSQSECTAEEAYTWSQGHAIFASGSPFDPVEYEGRTFVP 481

Query: 532 GQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKI 591
           GQANNAYIFPGFGLGLI+ GAIRV D+MLLAASEALA+QV+ E++ KGLIYPPF +IRKI
Sbjct: 482 GQANNAYIFPGFGLGLIMCGAIRVHDDMLLAASEALASQVTGEHFIKGLIYPPFKDIRKI 541

Query: 592 SAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           SAHIAA VAAK YELGLAS LP+P DLVK+AESCMY+P YRS+
Sbjct: 542 SAHIAAGVAAKAYELGLASRLPQPADLVKFAESCMYNPTYRSF 584


>MAOC_LYCES (P37222) NADP-dependent malic enzyme, chloroplast (EC
           1.1.1.40) (NADP-ME) (Fragment)
          Length = 573

 Score =  929 bits (2400), Expect = 0.0
 Identities = 458/570 (80%), Positives = 518/570 (90%), Gaps = 2/570 (0%)

Query: 65  SEESGGVRDLYGEDSATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTEKERDAHYLRGL 124
           S  +GGV+D+YGEDSATEDQ ITPWT SVASG +LLR+P YNKGLAF+E+ERD HYLRGL
Sbjct: 5   STVTGGVQDVYGEDSATEDQSITPWTLSVASGFSLLRNPHYNKGLAFSERERDTHYLRGL 64

Query: 125 LPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMDLQERNERLFYKILIDNVEELLPIVYT 184
           LPP V + +LQ K+ M++IR+Y+VPL +YMAMMDLQE NERLFYK+LIDNVEELLPIVYT
Sbjct: 65  LPPVVISHDLQVKKMMNSIRKYDVPLQRYMAMMDLQEMNERLFYKLLIDNVEELLPIVYT 124

Query: 185 PVVGEACQKYGSIYKRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTDGERILGLGDLG 244
           P VGEACQKYG I+KRPQGL+ SLKEKGKI EVLKNWPEK IQVIVVTDGERILGLGDLG
Sbjct: 125 PTVGEACQKYGWIFKRPQGLFFSLKEKGKIHEVLKNWPEKKIQVIVVTDGERILGLGDLG 184

Query: 245 CQGMGIPVGKLSLYTALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGLRQKRATGKEYEE 304
           CQGMGIPVGKLSLY+ALGG+RPS+CLPVTIDVG   +  ++DEFY GLRQ+RATG+EY E
Sbjct: 185 CQGMGIPVGKLSLYSALGGIRPSACLPVTIDVGQTMK-FVDDEFYIGLRQRRATGQEYSE 243

Query: 305 LLDEFMRAVKQNYGEKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQGTASVVLAGLLA 364
           LLDEFM AVKQNYGEKVLIQFEDFANHNAFNLL +Y +SHLVFNDDIQGTASVVLAGL+A
Sbjct: 244 LLDEFMYAVKQNYGEKVLIQFEDFANHNAFNLLAKYGTSHLVFNDDIQGTASVVLAGLMA 303

Query: 365 SLKLVGGTLADHTFLFLGAGEAGTGIAELIALEISKQTKAPVEETRKKVWLVDSKGLIVR 424
           +L LVGG+L++HTFLFLGAGEAGTGIAELIALE+SKQT  P+EETRKK+W+VDSKGLIV+
Sbjct: 304 ALNLVGGSLSEHTFLFLGAGEAGTGIAELIALEMSKQTGIPLEETRKKIWMVDSKGLIVK 363

Query: 425 SRLESLQHFKKPWAHEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKP 484
           SR+E LQHFK+PWAH+HEPV+ L++AVK+IKPTVLIGSSG G+TFTKEVV+AMA+ NEKP
Sbjct: 364 SRMEMLQHFKRPWAHDHEPVQELVNAVKSIKPTVLIGSSGAGRTFTKEVVQAMATFNEKP 423

Query: 485 LILALSNPTSQSECTAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFG 544
           +I ALSNPTSQSECTAEEAY+WS+G+AIFASGSPF PV+Y GKVYA GQANNAYIFPGFG
Sbjct: 424 IIFALSNPTSQSECTAEEAYSWSEGRAIFASGSPFAPVEYNGKVYASGQANNAYIFPGFG 483

Query: 545 LGLIISGAIRVRDEMLLAASEALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVY 604
           LGLIISGAIRV D+MLL ASEALA +VSQEN++KG   PPF+NIRKISAHI A VAAK Y
Sbjct: 484 LGLIISGAIRVHDDMLLVASEALADEVSQENFEKGTHIPPFSNIRKISAHI-AKVAAKAY 542

Query: 605 ELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           ELGLA+ LP+PKDLV YAESCMYSP YRSY
Sbjct: 543 ELGLATRLPQPKDLVAYAESCMYSPAYRSY 572


>MAOC_MAIZE (P16243) NADP-dependent malic enzyme, chloroplast
           precursor (EC 1.1.1.40) (NADP-ME)
          Length = 636

 Score =  889 bits (2298), Expect = 0.0
 Identities = 430/556 (77%), Positives = 500/556 (89%)

Query: 79  SATEDQLITPWTFSVASGNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKR 138
           +A+E+  + PW  SVASG TLLRDP +NKGLAFTE+ERD HYLRGLLPPAV +QELQ K+
Sbjct: 80  AASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKK 139

Query: 139 TMHNIRQYEVPLHKYMAMMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIY 198
            M+ +RQY+ PL +Y+AMM+LQE +ERLFYK+LIDNV ELLP VYTP VGEACQKYGSI+
Sbjct: 140 FMNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIF 199

Query: 199 KRPQGLYISLKEKGKILEVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLY 258
            RPQGLY+SLK+KGK+LEVL+NWP + IQVI VTDGERILGLGDLGCQGMGIPVGKL+LY
Sbjct: 200 GRPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALY 259

Query: 259 TALGGVRPSSCLPVTIDVGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYG 318
           TALGGV PS CLP+TIDVGTNNE LLNDEFY GLRQKRATG+EY+EL++EFM AVKQ YG
Sbjct: 260 TALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGLRQKRATGEEYDELIEEFMSAVKQFYG 319

Query: 319 EKVLIQFEDFANHNAFNLLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTF 378
           EKVLIQFEDFANHNAF+LL++YS SHLVFNDDIQGTASVVLAGLLA+LK+VGGTLA+ T+
Sbjct: 320 EKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTY 379

Query: 379 LFLGAGEAGTGIAELIALEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWA 438
           LFLGAGEAGTGIAELIALEISKQT AP+EE RKKVWLVDSKGLIV SR  SLQ FKKPWA
Sbjct: 380 LFLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWA 439

Query: 439 HEHEPVKALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSEC 498
           HEHEP+K L DAV++IKPTVLIG+SGVG+TFTKE++EAM+S NE+P+I +LSNPTS SEC
Sbjct: 440 HEHEPLKTLYDAVQSIKPTVLIGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSEC 499

Query: 499 TAEEAYTWSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDE 558
           TAE+AYTWS+G++IFASGSPF PV+Y GK + PGQ+NNAYIFPG GLGL+ISGA+RV ++
Sbjct: 500 TAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYIFPGLGLGLVISGAVRVHED 559

Query: 559 MLLAASEALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDL 618
           MLLAAS+ALA Q +Q+N++KG I+PPFT+IRKISAHIAA+VA K YELGLA+ LP P DL
Sbjct: 560 MLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAGKAYELGLATRLPPPSDL 619

Query: 619 VKYAESCMYSPGYRSY 634
           VKYAE+CMY+P YR+Y
Sbjct: 620 VKYAENCMYTPVYRNY 635


>MAOX_ANAPL (P28227) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 557

 Score =  576 bits (1485), Expect = e-164
 Identities = 286/541 (52%), Positives = 379/541 (69%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  +LRDP  NKG+AFT +ER    + GLLPP    Q++Q    + N  +    L +Y+ 
Sbjct: 4   GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDVQVFSILKNFERLTSDLDRYIL 63

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +M LQ+RNE+LFYK+L  ++E  +PIVYTP VG ACQ+YG  ++RP+GL+I++ ++G I 
Sbjct: 64  LMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIA 123

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            +LK+WPE  I+ IVVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV+P  CLPV +D
Sbjct: 124 TMLKSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHECLPVMLD 183

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT+NE LL D  Y GLR KR  G+ Y++LLDEFM AV   YG   LIQFEDFAN NAF 
Sbjct: 184 VGTDNEALLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFR 243

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL +Y + +  FNDDIQGTASV +AGLLA+L++    L+DHT LF GAGEA  GIA LI 
Sbjct: 244 LLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIV 303

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+  +  E   K++W+VDSKGLIV+ R  SL   K  +AHEH  +K L D VK IK
Sbjct: 304 MAMEKEGVSK-EAAVKRIWMVDSKGLIVKGR-ASLTAEKTRFAHEHAEMKNLEDIVKDIK 361

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           P+VLIG + +G  FTKE+++ MA+ N++P+I ALSNPTS++ECTAE+ Y +++G+ IFAS
Sbjct: 362 PSVLIGVAAIGGAFTKEILQDMAAFNKRPIIFALSNPTSKAECTAEQCYKYTEGRGIFAS 421

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    GK   PGQ NN+Y+FPG  LG+I  G   + +++ L  +E +A QVS+E
Sbjct: 422 GSPFDPVTLPNGKTLYPGQGNNSYVFPGVALGVIACGLKHIGEDVFLTTAEVIAEQVSEE 481

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           N  +G +YPP   I+ +S  IA  +A + Y    AS  P+PKDL  + +S +YS  Y S+
Sbjct: 482 NLQEGRLYPPLVTIQHVSLKIAVRIAEEAYRNNTASTYPQPKDLEAFIQSQIYSTDYNSF 541

Query: 635 L 635
           +
Sbjct: 542 V 542


>MAOX_COLLI (P40927) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME)
          Length = 557

 Score =  571 bits (1471), Expect = e-162
 Identities = 283/541 (52%), Positives = 379/541 (69%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  +LRDP  NKG+AFT +ER    + GLLPP    Q+ Q    + N  +    L +Y+ 
Sbjct: 4   GYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDAQVYSILKNFERLTSDLDRYIL 63

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +M LQ+RNE+LFYK+L  ++E  +PIVYTP VG ACQ YG  ++RP+GL+I++ ++G I 
Sbjct: 64  LMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQHYGLAFRRPRGLFITIHDRGHIA 123

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            +L++WPE  I+ IVVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV+P  CLPV +D
Sbjct: 124 TMLQSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHQCLPVMLD 183

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT+NETLL D  Y GLR KR  G+ Y++LLDEFM AV   YG   LIQFEDFAN NAF 
Sbjct: 184 VGTDNETLLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFR 243

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL +Y + +  FNDDIQGTASV +AGLLA+L++    L+DHT LF GAGEA  GIA LI 
Sbjct: 244 LLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIV 303

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+  +  EE  K++W+VDSKGLIV+ R  SL   K+ +AHEH  +K L D VK IK
Sbjct: 304 MAMQKEGVSK-EEAIKRIWMVDSKGLIVKGR-ASLTPEKEHFAHEHCEMKNLEDIVKDIK 361

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PTVLIG + +G  FT+++++ MA+ N++P+I ALSNPTS++ECTAE+ Y +++G+ IFAS
Sbjct: 362 PTVLIGVAAIGGAFTQQILQDMAAFNKRPIIFALSNPTSKAECTAEQLYKYTEGRGIFAS 421

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    G+   PGQ NN+Y+FPG  LG+I  G   + D++ L  +E +A +VS+E
Sbjct: 422 GSPFDPVTLPSGQTLYPGQGNNSYVFPGVALGVISCGLKHIGDDVFLTTAEVIAQEVSEE 481

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           N  +G +YPP   I+++S  IA  +A + Y    AS  P+P+DL  +  S +YS  Y  +
Sbjct: 482 NLQEGRLYPPLVTIQQVSLKIAVRIAKEAYRNNTASTYPQPEDLEAFIRSQVYSTDYNCF 541

Query: 635 L 635
           +
Sbjct: 542 V 542


>MAOX_RAT (P13697) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME) (Malic enzyme 1)
          Length = 572

 Score =  565 bits (1456), Expect = e-160
 Identities = 280/541 (51%), Positives = 370/541 (67%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L RDP  NK LAFT +ER    + GLLPP +  QE+Q  R + N  +      +Y+ 
Sbjct: 15  GYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLL 74

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +MDLQ+RNE+LFY +L+ NVE+ +PIVYTP VG ACQ+Y   +++P+GL+IS+ +KG I 
Sbjct: 75  LMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIA 134

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            VL  WPE  ++ IVVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV P  CLP+T+D
Sbjct: 135 SVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLD 194

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT NE LL D  Y GLR +R  G EY+  LDEFM A    YG   LIQFEDFAN NAF 
Sbjct: 195 VGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFR 254

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL++Y + +  FNDDIQGTASV +AGLLA+L++    L+D T LF GAGEA  GIA LI 
Sbjct: 255 LLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIV 314

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+  +  E+ R+K+WLVDSKGLIV+ R  SL   K+ +AHEHE +K L   V+ IK
Sbjct: 315 MAMEKEGLSK-EKARQKIWLVDSKGLIVKGR-ASLTEEKEVFAHEHEEMKNLEAIVQKIK 372

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PT LIG + +G  FT+++++ MA+ NE+P+I ALSNPTS++EC+AEE Y  +KG+AIFAS
Sbjct: 373 PTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFAS 432

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    G+   PGQ NN+Y+FPG  LG++  G   + D + L  +E ++ QVS +
Sbjct: 433 GSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDK 492

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           + ++G +YPP   IR +S  IA  +    Y+  +A+  P P++  ++  S MYS  Y   
Sbjct: 493 HLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQI 552

Query: 635 L 635
           L
Sbjct: 553 L 553


>MAOX_MOUSE (P06801) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME) (Malic enzyme 1)
          Length = 572

 Score =  561 bits (1445), Expect = e-159
 Identities = 278/541 (51%), Positives = 369/541 (67%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L RDP  NK LAFT +ER    + GLLPP + +QELQ  R + N  +      +Y+ 
Sbjct: 15  GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLL 74

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +MDLQ+RNE+LFY +L+ +VE+ +PIVYTP VG ACQ+Y   +++P+GL+IS+ +KG I 
Sbjct: 75  LMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIA 134

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            VL  WPE  ++ IVVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV P  CLP+T+D
Sbjct: 135 SVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLD 194

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT NE LL D  Y GLR +R  G EY+  LDEFM A    YG   LIQFEDFAN NAF 
Sbjct: 195 VGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFR 254

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL++Y + +  FNDDIQGTASV +AGLLA+L++    L+D T LF GAGEA  GIA L+ 
Sbjct: 255 LLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVV 314

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+  +  E  RKK+WLVDSKGLIV+ R  SL   K+ +AHEHE +K L   V+ IK
Sbjct: 315 MAMEKEGLSK-ENARKKIWLVDSKGLIVKGR-ASLTEEKEVFAHEHEEMKNLEAIVQKIK 372

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PT LIG + +G  FT+++++ MA+ NE+P+I ALS+PTS++EC+A+E Y  +KG+AIFAS
Sbjct: 373 PTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSSPTSKAECSADECYKVTKGRAIFAS 432

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    G+   PGQ NN+Y+FPG  LG++  G   + D++ L   E ++ QVS +
Sbjct: 433 GSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTREVISQQVSDK 492

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           +  +G +YPP   IR +S  IA  +    Y+  +A+  P P++  ++  S MYS  Y   
Sbjct: 493 HLQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQI 552

Query: 635 L 635
           L
Sbjct: 553 L 553


>MAOX_HUMAN (P48163) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME) (Malic enzyme 1)
          Length = 572

 Score =  558 bits (1439), Expect = e-158
 Identities = 277/541 (51%), Positives = 371/541 (68%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L R+P  NK LAFT +ER    + GLLPP+  +QE+Q  R + N         +Y+ 
Sbjct: 15  GYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLL 74

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +MDLQ+RNE+LFY++L  ++E+ +PIVYTP VG ACQ+Y  ++++P+GL+I++ ++G I 
Sbjct: 75  LMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIA 134

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            VL  WPE  I+ IVVTDGERILGLGDLGC GMGIPVGKL+LYTA GG+ P  CLPV +D
Sbjct: 135 SVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILD 194

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT NE LL D  Y GLRQ+R  G EY++ LDEFM AV   YG   LIQFEDFAN NAF 
Sbjct: 195 VGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFR 254

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL++Y + +  FNDDIQGTASV +AGLLA+L++    L+D T LF GAGEA  GIA LI 
Sbjct: 255 LLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIV 314

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+   P E+  KK+WLVDSKGLIV+ R  SL   K+ +AHEHE +K L   V+ IK
Sbjct: 315 MALEKE-GLPKEKAIKKIWLVDSKGLIVKGR-ASLTQEKEKFAHEHEEMKNLEAIVQEIK 372

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PT LIG + +G  F++++++ MA+ NE+P+I ALSNPTS++EC+AE+ Y  +KG+AIFAS
Sbjct: 373 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFAS 432

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    G+   PGQ NN+Y+FPG  LG++  G  ++ D + L  +E +A QVS +
Sbjct: 433 GSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDK 492

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           + ++G +YPP   IR +S  IA  +    Y+   A+  P P++   +  S MYS  Y   
Sbjct: 493 HLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQI 552

Query: 635 L 635
           L
Sbjct: 553 L 553


>MAON_HUMAN (Q16798) NADP-dependent malic enzyme, mitochondrial
           precursor (EC 1.1.1.40) (NADP-ME) (Malic enzyme 3)
          Length = 604

 Score =  556 bits (1432), Expect = e-158
 Identities = 270/540 (50%), Positives = 375/540 (69%), Gaps = 3/540 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  + R+P  NKG+AFT +ER    + GL+PP   +Q++Q  R M    + +  L KY+ 
Sbjct: 50  GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +M LQ+RNE+LFY++L  +VE+ +PIVYTP VG ACQ YG  ++RP+GL+I++ +KG + 
Sbjct: 110 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLA 169

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            +L +WPE  I+ +VVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV P  CLPV +D
Sbjct: 170 TMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGTNNE LL D  Y GL+ +R  GK Y++LLDEFM+AV   +G   LIQFEDFAN NAF 
Sbjct: 230 VGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFR 289

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL++Y + + +FNDDIQGTASV +AG+LA+L++    L++H F+F GAGEA  GIA L+ 
Sbjct: 290 LLNKYRNKYCMFNDDIQGTASVAVAGILAALRITNNKLSNHVFVFQGAGEAAMGIAHLLV 349

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+   P  E  +K+W+VDSKGLIV+ R   L H K+ +A +H  V +L + V+ +K
Sbjct: 350 MALEKE-GVPKAEATRKIWMVDSKGLIVKGR-SHLNHEKEMFAQDHPEVNSLEEVVRLVK 407

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PT +IG + +   FT++++  MAS +E+P+I ALSNPTS++ECTAE+ Y  ++G+ IFAS
Sbjct: 408 PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFAS 467

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPF  V    GK + PGQ NNAY+FPG  LG+I  G   + DE+ L  +E +A +VS++
Sbjct: 468 GSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQ 527

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           +  +G +YPP + IR +S  IA  V    Y+  LAS+ P PKD   +  S +Y+P Y S+
Sbjct: 528 HLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSF 587


>MAOX_PIG (Q29558) NADP-dependent malic enzyme (EC 1.1.1.40)
           (NADP-ME) (Malic enzyme 1) (Fragment)
          Length = 557

 Score =  555 bits (1430), Expect = e-157
 Identities = 275/541 (50%), Positives = 368/541 (67%), Gaps = 3/541 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L R P  NK LAFT +ER    + GLLPP   +Q++Q  R + N  +      +Y+ 
Sbjct: 1   GYGLTRIPHLNKDLAFTLEERQQLNIHGLLPPCFISQDIQVLRVIKNFERLNSDFDRYLL 60

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +MDLQ+RNE+LFYK+L+ ++E+ +PIVYTP VG ACQ+Y   +++P+GL+IS+ ++G + 
Sbjct: 61  LMDLQDRNEKLFYKVLMSDIEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDRGHVA 120

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            VL  WPE  I+ +VVTDGERILGLGDLGC GMGIPVGKL+LYTA GGV P  CLPV +D
Sbjct: 121 SVLNAWPEDVIKAVVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQECLPVILD 180

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT NE LL D  Y GLRQ+R  G EY++ LDEFM AV   YG   LIQFEDFAN NAF 
Sbjct: 181 VGTENEELLKDPLYIGLRQRRVRGPEYDDFLDEFMEAVSSKYGMNCLIQFEDFANINAFR 240

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
           LL +Y + +  FNDDIQGTASV +AG+LA+L++    L+D T LF GAGEA  GIA LI 
Sbjct: 241 LLKKYQNQYCTFNDDIQGTASVAVAGILAALRITKNKLSDQTILFQGAGEAALGIAHLIV 300

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHEPVKALLDAVKAIK 455
           + + K+   P E+  KK+WLVDSKGLIV+ R  +L + K+ +AHEHE +K L   V+ IK
Sbjct: 301 MAMEKE-GVPKEKAIKKIWLVDSKGLIVKGR-AALTNEKEEFAHEHEEMKNLEAIVQDIK 358

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           PT LIG + +G  F++++++ MA+ NE+P+I ALSNPTS++ECTAE  YT ++G+AIFAS
Sbjct: 359 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECTAERGYTLTQGRAIFAS 418

Query: 516 GSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQE 574
           GSPFDPV    G+   PGQ NN+Y+FPG  L ++  G   + D++ L  +E +A QVS +
Sbjct: 419 GSPFDPVTLPSGQTLYPGQGNNSYVFPGVALAVVACGLRHITDKIFLTTAEVIAQQVSDK 478

Query: 575 NYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSY 634
           + ++G +YPP   IR +S  IA  +    Y+   A+  P P +   +  S MYS  Y   
Sbjct: 479 HLEEGRLYPPLNTIRDVSLKIAEKIVRDAYQEKTATIYPEPSNKEAFVRSQMYSTDYDQI 538

Query: 635 L 635
           L
Sbjct: 539 L 539


>MAOM_HUMAN (P23368) NAD-dependent malic enzyme, mitochondrial
           precursor (EC 1.1.1.38) (NAD-ME) (Malic enzyme 2)
          Length = 584

 Score =  554 bits (1428), Expect = e-157
 Identities = 269/543 (49%), Positives = 373/543 (68%), Gaps = 4/543 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L+ +PR NKG+AFT +ER    L+GLLPP + TQ++Q  R   N+++   PL KY+ 
Sbjct: 25  GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIY 84

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +M +QERNE+LFY+IL D++E L+PIVYTP VG AC +YG I++RP+GL+IS+ ++G + 
Sbjct: 85  IMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVR 144

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            ++ NWPE  ++ +VVTDGERILGLGDLG  GMGIPVGKL LYTA  G+RP  CLPV ID
Sbjct: 145 SIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCID 204

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT+N  LL D FY GL QKR   ++Y++L+DEFM+A+   YG   LIQFEDF NHNAF 
Sbjct: 205 VGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFR 264

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
            L +Y   +  FNDDIQGTA+V LAGLLA+ K++   +++H  LFLGAGEA  GIA LI 
Sbjct: 265 FLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIV 324

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHE--HEPVKALLDAVKA 453
           + + +   +  +E +KK+W+ D  GL+V+ R   +  +++P+ H           DAV  
Sbjct: 325 MSMVENGLSE-QEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNI 383

Query: 454 IKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIF 513
           +KP+ +IG +G G+ FT +V+ AMAS+NE+P+I ALSNPT+Q+ECTAEEAYT ++G+ +F
Sbjct: 384 LKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLF 443

Query: 514 ASGSPFDPVKY-GGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVS 572
           ASGSPF PVK   G+V+ PGQ NN YIFPG  L +I+     + D + L A++AL +Q++
Sbjct: 444 ASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLT 503

Query: 573 QENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYR 632
            E   +G +YPP  NI+++S +IA  V   +Y   +A   P P+D  KY +   +   Y 
Sbjct: 504 DEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYD 563

Query: 633 SYL 635
           S L
Sbjct: 564 SLL 566


>MAOM_MOUSE (Q99KE1) NAD-dependent malic enzyme, mitochondrial
           precursor (EC 1.1.1.38) (NAD-ME) (Malic enzyme 2)
          Length = 589

 Score =  551 bits (1420), Expect = e-156
 Identities = 271/543 (49%), Positives = 378/543 (68%), Gaps = 4/543 (0%)

Query: 96  GNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMA 155
           G  L+ +PR NKG+AFT +ER    L+GLLPP + TQ++Q  R   N+++   PL KY+ 
Sbjct: 25  GKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIY 84

Query: 156 MMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKIL 215
           +M +QERNE+LFY+IL D++E L+PIVYTP VG AC +YG I++RP+GL+IS+ ++G + 
Sbjct: 85  IMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVR 144

Query: 216 EVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTID 275
            ++ NWPE  ++ +VVTDGERILGLGDLG  GMGIPVGKL LYTA  G++P  CLPV ID
Sbjct: 145 SIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCID 204

Query: 276 VGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFN 335
           VGT+N  LL D FY GL QKR   + Y++L+DEFM+A+   YG   LIQFEDF NHNAF 
Sbjct: 205 VGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFR 264

Query: 336 LLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIA 395
            L +Y   +  FNDDIQGTA+V L+GLLA+ +++   +++H  LFLGAGEA  GIA LI 
Sbjct: 265 FLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIV 324

Query: 396 LEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAH-EHEPVKALL-DAVKA 453
           L +  ++    EE ++K+W+ D  GL+V+ R  S+   ++P+AH   E + A   DAV  
Sbjct: 325 LSM-VESGLSEEEAQRKIWMFDKSGLLVKGRTASIDSNQEPYAHAAPESIPATFEDAVNK 383

Query: 454 IKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIF 513
           +KP+V+IG +G G  FT  V++AMAS+NE+P+I ALSNPT+Q+ECTAE+AYT ++G+ +F
Sbjct: 384 LKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLF 443

Query: 514 ASGSPFDPVK-YGGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVS 572
           ASGSPF+PVK   G+V+ PGQ NNAYIFPG  L +I+  A  + D + L A++AL  Q++
Sbjct: 444 ASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLT 503

Query: 573 QENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYR 632
                +G +YP   NI+++SA+IA  +A  +Y   +A   P P+D  +Y    ++   Y 
Sbjct: 504 DAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYVRERIWRSNYV 563

Query: 633 SYL 635
           S L
Sbjct: 564 SLL 566


>MAOM_ASCSU (P27443) NAD-dependent malic enzyme, mitochondrial
           precursor (EC 1.1.1.38) (NAD-ME) (Fragment)
          Length = 643

 Score =  523 bits (1346), Expect = e-148
 Identities = 264/540 (48%), Positives = 372/540 (68%), Gaps = 6/540 (1%)

Query: 99  LLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYMAMMD 158
           LL++PR NKG+ F+  ER    L GLLPPA  TQE Q  R +  +R+    L +Y+ +  
Sbjct: 80  LLKEPRLNKGMGFSLYERQYLGLHGLLPPAFMTQEQQAYRVITKLREQPNDLARYIQLDG 139

Query: 159 LQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKG--KILE 216
           LQ+RNE+LFY+++ D+V+EL+PIVYTP VG ACQ +G IY++P+GLYI++ +    KI +
Sbjct: 140 LQDRNEKLFYRVVCDHVKELMPIVYTPTVGLACQNFGYIYRKPKGLYITINDNSVSKIYQ 199

Query: 217 VLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTIDV 276
           +L NW E+ ++ IVVTDGERILGLGDLG  G+GIPVGKL+LY ALGGV+P  CLPV +DV
Sbjct: 200 ILSNWHEEDVRAIVVTDGERILGLGDLGAYGIGIPVGKLALYVALGGVQPKWCLPVLLDV 259

Query: 277 GTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAFNL 336
           GTNN  LLND FY GLR KR  GK+Y+ LLD FM+A  + YG+K LIQFEDFAN NAF L
Sbjct: 260 GTNNMDLLNDPFYIGLRHKRVRGKDYDTLLDNFMKACTKKYGQKTLIQFEDFANPNAFRL 319

Query: 337 LDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELIAL 396
           LD+Y   + +FNDDIQGTASV++AGLL   ++    ++   +LF GAG A TGIAE+I  
Sbjct: 320 LDKYQDKYTMFNDDIQGTASVIVAGLLTCTRVTKKLVSQEKYLFFGAGAASTGIAEMIVH 379

Query: 397 EISKQTKAPVEETRKKVWLVDSKGLIVRSRLE-SLQHFKKPWAHEHEPVKALLDAVKAIK 455
           ++  +  +  EE   +++L+D  GL+ ++R E + +H +  +A +     ++L+ ++A +
Sbjct: 380 QMQNEGISK-EEACNRIYLMDIDGLVTKNRKEMNPRHVQ--FAKDMPETTSILEVIRAAR 436

Query: 456 PTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYTWSKGKAIFAS 515
           P  LIG+S V   F +EV+ AMA +NE+P+I ALSNPTS++ECTAEEAYT++ G A++AS
Sbjct: 437 PGALIGASTVRGAFNEEVIRAMAEINERPIIFALSNPTSKAECTAEEAYTFTNGAALYAS 496

Query: 516 GSPFDPVKYGGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASEALAAQVSQEN 575
           GSPF   +  G  Y PGQ NNAYIFPG  LG I+     V +++ L A++ +A+ V++++
Sbjct: 497 GSPFPNFELNGHTYKPGQGNNAYIFPGVALGTILFQIRHVDNDLFLLAAKKVASCVTEDS 556

Query: 576 YDKGLIYPPFTNIRKISAHIAASVAAKVYELGLASHLPRPKDLVKYAESCMYSPGYRSYL 635
              G +YP    IR+IS  IA  +A   Y+ G A+  P+P+DL KY  + +Y+  Y   +
Sbjct: 557 LKVGRVYPQLKEIREISIQIAVEMAKYCYKNGTANLYPQPEDLEKYVRAQVYNTEYEELI 616


>MAO1_ECOLI (P26616) NAD-dependent malic enzyme (EC 1.1.1.38)
           (NAD-ME)
          Length = 574

 Score =  436 bits (1122), Expect = e-122
 Identities = 231/524 (44%), Positives = 340/524 (64%), Gaps = 12/524 (2%)

Query: 95  SGNTLLRDPRYNKGLAFTEKERDAHYLRGLLPPAVFTQELQEKRTMHNIRQYEVPLHKYM 154
           +G  LL  P  NKG AF+ +ER    L GLLP  V T E Q +R     + ++  + K++
Sbjct: 25  AGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHI 84

Query: 155 AMMDLQERNERLFYKILIDNVEELLPIVYTPVVGEACQKYGSIYKRPQGLYISLKEKGKI 214
            + ++Q+ NE LFY+++ ++++E++P++YTP VG AC+++  IY+R +G++IS + +  +
Sbjct: 85  YLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNM 144

Query: 215 LEVLKNWPEKTIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSSCLPVTI 274
            ++L+N P   I+VIVVTDGERILGLGD G  GMGIP+GKLSLYTA GG+ P+  LPV +
Sbjct: 145 DDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVL 204

Query: 275 DVGTNNETLLNDEFYTGLRQKRATGKEYEELLDEFMRAVKQNYGEKVLIQFEDFANHNAF 334
           DVGTNN+ LLND  Y G R  R T  EY E +DEF++AVKQ + + VL+QFEDFA  NA 
Sbjct: 205 DVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPD-VLLQFEDFAQKNAM 263

Query: 335 NLLDRYSSSHLVFNDDIQGTASVVLAGLLASLKLVGGTLADHTFLFLGAGEAGTGIAELI 394
            LL+RY +    FNDDIQGTA+V +  L+A+ +  GG L++   +FLGAG AG GIAE+I
Sbjct: 264 PLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMI 323

Query: 395 ALEISKQTKAPVEETRKKVWLVDSKGLIVRSRLESLQHFKKPWAHEHE---------PVK 445
             +  ++  +  E  R+KV++VD  GL+   ++ +L  F+     + E          V 
Sbjct: 324 ISQTQREGLSE-EAARQKVFMVDRFGLLT-DKMPNLLPFQTKLVQKRENLSDWDTDSDVL 381

Query: 446 ALLDAVKAIKPTVLIGSSGVGKTFTKEVVEAMASLNEKPLILALSNPTSQSECTAEEAYT 505
           +LLD V+ +KP +LIG SG    FT+E++  M     +P+++ LSNPTS+ E T ++   
Sbjct: 382 SLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIA 441

Query: 506 WSKGKAIFASGSPFDPVKYGGKVYAPGQANNAYIFPGFGLGLIISGAIRVRDEMLLAASE 565
           W++G A+ A+GSPF+PV +  K+Y   Q NNA+IFPG GLG+I SGA R+ DEML++ASE
Sbjct: 442 WTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASE 501

Query: 566 ALAAQVSQENYDKGLIYPPFTNIRKISAHIAASVAAKVYELGLA 609
            LA         +G++ P   +I+K+S  IA +V     + G+A
Sbjct: 502 TLAQYSPLVLNGEGMVLPELKDIQKVSRAIAFAVGKMAQQQGVA 545


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.318    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,007,140
Number of Sequences: 164201
Number of extensions: 3404200
Number of successful extensions: 9846
Number of sequences better than 10.0: 62
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 9687
Number of HSP's gapped (non-prelim): 72
length of query: 635
length of database: 59,974,054
effective HSP length: 116
effective length of query: 519
effective length of database: 40,926,738
effective search space: 21240977022
effective search space used: 21240977022
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)