BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0333b.9
(488 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CP22_HORVU (P55748) Serine carboxypeptidase II-2 precursor (EC 3... 411 e-114
CBP2_HORVU (P08818) Serine carboxypeptidase II precursor (EC 3.4... 402 e-111
CBP2_WHEAT (P08819) Serine carboxypeptidase II chains A and B (E... 399 e-111
CP23_HORVU (P52711) Serine carboxypeptidase II-3 precursor (EC 3... 387 e-107
NF31_NAEFO (P42661) Virulence-related protein Nf314 (EC 3.4.16.-) 281 2e-75
CP21_HORVU (P55747) Serine carboxypeptidase II-1 precursor (EC 3... 280 5e-75
CBP1_ORYSA (P37890) Serine carboxypeptidase I precursor (EC 3.4.... 254 4e-67
YSS2_CAEEL (Q09991) Putative serine carboxypeptidase K10B2.2 pre... 246 7e-65
CBP1_HORVU (P07519) Serine carboxypeptidase I precursor (EC 3.4.... 236 8e-62
YUW5_CAEEL (P52717) Putative serine carboxypeptidase F41C3.5 pre... 228 3e-59
YUA6_CAEEL (P52715) Putative serine carboxypeptidase F13S12.6 pr... 226 1e-58
PRTP_MOUSE (P16675) Lysosomal protective protein precursor (EC 3... 225 2e-58
PRTP_HUMAN (P10619) Lysosomal protective protein precursor (EC 3... 213 7e-55
YXD2_CAEEL (P52714) Putative serine carboxypeptidase C08H9.1 (EC... 209 1e-53
YPP3_CAEEL (P52716) Putative serine carboxypeptidase F32A5.3 pre... 184 3e-46
CBPY_SCHPO (O13849) Carboxypeptidase Y precursor (EC 3.4.16.5) (... 180 6e-45
YBY9_YEAST (P38109) Putative serine carboxypeptidase in ESR1-IRA... 179 1e-44
CBP3_HORVU (P21529) Serine carboxypeptidase III precursor (EC 3.... 179 1e-44
CPVL_HUMAN (Q9H3G5) Probable serine carboxypeptidase CPVL precur... 174 5e-43
CBPX_ORYSA (P52712) Serine carboxypeptidase-like precursor (EC 3... 172 1e-42
>CP22_HORVU (P55748) Serine carboxypeptidase II-2 precursor (EC
3.4.16.6) (CP-MII.2) (Fragment)
Length = 436
Score = 411 bits (1057), Expect = e-114
Identities = 204/436 (46%), Positives = 289/436 (65%), Gaps = 14/436 (3%)
Query: 52 LPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGPGCSSVGYGA 111
+PG S +H++GY+TV+ED G ALFYWFFEA +P+ KPLLLWLNGGPGCSS+ +G
Sbjct: 4 VPGQAFDASFAHYAGYVTVSEDRGAALFYWFFEAAHDPASKPLLLWLNGGPGCSSIAFGV 63
Query: 112 AIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILEDNFVAED 171
E+GP VN +G+G++ NPYSWNQ AN+LF++SPVGVG+SY+NTS+D+ D A+D
Sbjct: 64 GEEVGPFHVNADGKGVHMNPYSWNQVANILFLDSPVGVGYSYSNTSADILSNGDERTAKD 123
Query: 172 AYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPFINLKGFIVG 231
+ FL WL+RFPQ+K R F+++GESY GHY+PQLA+ I R+ + INLKG++VG
Sbjct: 124 SLVFLTKWLERFPQYKEREFYLTGESYAGHYVPQLAQAI-KRHHEATGDKSINLKGYMVG 182
Query: 232 NPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQF-QWSNECNKAMNEVFQDYSE 290
N T+D++D+ G+ +Y W+ +ISDQ Y CDF+ F S +C+K ++ +
Sbjct: 183 NALTDDFHDHYGIFQYMWTTGLISDQTYKLLNIFCDFESFVHTSPQCDKILDIASTEAGN 242
Query: 291 IDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFGGYDPCYSTYAEKYFNRI 350
ID Y+I+ P C S+ AS + + + R+ +M + YDPC ++ YFN
Sbjct: 243 IDSYSIFTPTCH----SSFASSRNKVVKRLRSVGKMGEQ-----YDPCTEKHSIVYFNLH 293
Query: 351 DVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIKGGLKIWIYSGDADG 410
+VQ + HVN G + WE C+ I + S+L IY +LI+ GL+IW++SGD D
Sbjct: 294 EVQKALHVNPVIGKSK--WETCSEVINTNWKDCERSVLHIYHELIQYGLRIWMFSGDTDA 351
Query: 411 RVPVIGTRYCVEALGLPLKSSWRSWYLDN-QVGGRIVEYEGLTYVTVRGAGHLVPLNKPK 469
+PV TRY ++AL LP + W +WY D+ +VGG Y+GL +VTVRGAGH VPL++PK
Sbjct: 352 VIPVTSTRYSIDALKLPTVTPWHAWYDDDGEVGGWTQGYKGLNFVTVRGAGHEVPLHRPK 411
Query: 470 EALSLIHSFLAGDRLP 485
+AL+LI SFLAG +P
Sbjct: 412 QALTLIKSFLAGRPMP 427
>CBP2_HORVU (P08818) Serine carboxypeptidase II precursor (EC
3.4.16.6) (Carboxypeptidase D) (CP-MII) [Contains:
Serine carboxypeptidase II chain A; Serine
carboxypeptidase II chain B]
Length = 476
Score = 402 bits (1032), Expect = e-111
Identities = 207/448 (46%), Positives = 282/448 (62%), Gaps = 16/448 (3%)
Query: 42 GANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGG 101
G + +DRIV LPG P +SGYITV+E GR+LFY EA E PL+LWLNGG
Sbjct: 36 GGHAADRIVRLPGQPEV-DFDMYSGYITVDEAAGRSLFYLLQEAPEEAQPAPLVLWLNGG 94
Query: 102 PGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLT 161
PGCSSV YGA+ E+G V G GL N Y WN+ AN+LF++SP GVGFSYTNTSSD+
Sbjct: 95 PGCSSVAYGASEELGAFRVMPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSSDIY 154
Query: 162 ILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYP 221
DN A D+Y FL W +RFP +K R F+++GESY GHY+P+L++L+ ++ P
Sbjct: 155 TSGDNRTAHDSYAFLAAWFERFPHYKYREFYVAGESYAGHYVPELSQLV-----HRSGNP 209
Query: 222 FINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQF-QWSNECNKA 280
INLKGF+VGN +DY+DY G E+ W+H ++SD Y + K C F S C+ A
Sbjct: 210 VINLKGFMVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKDACLHDSFIHPSPACDAA 269
Query: 281 MNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFGGYDPCYS 340
+ + ID+Y++Y P C ++S+S+ +S + T+GR + + G YDPC
Sbjct: 270 TDVATAEQGNIDMYSLYTPVCNISSSSSSSSLS-RRRTRGRYPW------LTGSYDPCTE 322
Query: 341 TYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIKGGLK 400
Y+ Y+NR DVQ++ H N G N TW C+++I ++ + S+LPIY +LI GL+
Sbjct: 323 RYSTAYYNRRDVQTALHANV-TGAMNYTWTNCSDTINTHWHDAPRSMLPIYRELIAAGLR 381
Query: 401 IWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLD-NQVGGRIVEYEGLTYVTVRGA 459
IW++SGD D VP+ TRY + ALGL +SW WY D +VGG Y+GLT V+VRGA
Sbjct: 382 IWVFSGDTDAVVPLTATRYSIGALGLATTTSWYPWYDDLQEVGGWSQVYKGLTLVSVRGA 441
Query: 460 GHLVPLNKPKEALSLIHSFLAGDRLPTR 487
GH VPL++P++AL L FL G +P R
Sbjct: 442 GHEVPLHRPRQALILFQQFLQGKPMPGR 469
>CBP2_WHEAT (P08819) Serine carboxypeptidase II chains A and B (EC
3.4.16.6) (Carboxypeptidase D) (CPDW-II) (CP-WII)
Length = 423
Score = 399 bits (1025), Expect = e-111
Identities = 201/448 (44%), Positives = 272/448 (59%), Gaps = 33/448 (7%)
Query: 39 INVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWL 98
+ + +DRI LPG P+ +SGYITV+E GR+LFY EA + PL+LWL
Sbjct: 1 VEPSGHAADRIARLPGQPAV-DFDMYSGYITVDEGAGRSLFYLLQEAPEDAQPAPLVLWL 59
Query: 99 NGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSS 158
NGGPGCSSV YGA+ E+G V G GL N Y WN+ AN+LF++SP GVGFSYTNTSS
Sbjct: 60 NGGPGCSSVAYGASEELGAFRVKPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSS 119
Query: 159 DLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKN 218
D+ DN A D+Y FL W +RFP +K R F+I+GESY GHY+P+L++L+ ++
Sbjct: 120 DIYTSGDNRTAHDSYAFLAKWFERFPHYKYRDFYIAGESYAGHYVPELSQLV-----HRS 174
Query: 219 KYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQF-QWSNEC 277
K P INLKGF+VGN +DY+DY G E+ W+H ++SD Y + K+ C F S C
Sbjct: 175 KNPVINLKGFMVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKEACLHDSFIHPSPAC 234
Query: 278 NKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFGGYDP 337
+ A + + ID+Y++Y P C + S++ G YDP
Sbjct: 235 DAATDVATAEQGNIDMYSLYTPVCNITSST-------------------------GSYDP 269
Query: 338 CYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIKG 397
C Y+ Y+NR DVQ + H N G N TW C+++I ++ + S+LPIY +LI
Sbjct: 270 CTERYSTAYYNRRDVQMALHANV-TGAMNYTWATCSDTINTHWHDAPRSMLPIYRELIAA 328
Query: 398 GLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLDNQVGGRIVEYEGLTYVTVR 457
GL+IW++SGD D VP+ TRY + ALGLP +SW WY D +VGG Y+GLT V+VR
Sbjct: 329 GLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWYDDQEVGGWSQVYKGLTLVSVR 388
Query: 458 GAGHLVPLNKPKEALSLIHSFLAGDRLP 485
GAGH VPL++P++AL L FL G +P
Sbjct: 389 GAGHEVPLHRPRQALVLFQYFLQGKPMP 416
>CP23_HORVU (P52711) Serine carboxypeptidase II-3 precursor (EC
3.4.16.6) (CP-MII.3)
Length = 516
Score = 387 bits (993), Expect = e-107
Identities = 207/460 (45%), Positives = 280/460 (60%), Gaps = 40/460 (8%)
Query: 39 INVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQ--SEPSKKPLLL 96
+ G E+DR+ LPG P + ++GY+TV+ GRALFY+ EA + KPLLL
Sbjct: 76 VEAGRKEADRVEALPGHPRGVDFAQYAGYVTVDAAAGRALFYYLAEAVGGNGDKTKPLLL 135
Query: 97 WLNGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNT 156
WLNGGPGCSS+GYGA E+GP V +G+ L NPYSWN AN+LF+ESP GVG+SY+NT
Sbjct: 136 WLNGGPGCSSLGYGAMEELGPFRVMSDGKTLYSNPYSWNHAANVLFLESPAGVGYSYSNT 195
Query: 157 SSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKD 216
++D DN AEDAY FL NWL+RFP++K R F+I+GESY GHY+PQLA I
Sbjct: 196 TADYGRSGDNGTAEDAYQFLDNWLERFPEYKGREFYITGESYAGHYVPQLAHAIL----- 250
Query: 217 KNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQF---QW 273
++ P INLKG ++GN D+ D KG+ ++ W+HA+ISD+ D + C+F +
Sbjct: 251 RHASPDINLKGIMIGNAVINDWTDSKGMYDFFWTHALISDETADGISKNCNFTAYGAGVA 310
Query: 274 SNE-CNKAMNEVFQDYSEIDIYNIYAPKCRLNS--TSAIASEGLEQLTKGRNDYRMKRKR 330
SN C+ A +EV + ++IDIYNIYAP C+ T IA
Sbjct: 311 SNALCDAASDEVGESLADIDIYNIYAPNCQSEKLVTPPIAPS------------------ 352
Query: 331 IFGGYDPCYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPI 390
+DPC Y E Y NR DVQ + H N R + W C++ +L + S ++LPI
Sbjct: 353 -IDNFDPCTDYYVEAYLNRPDVQKALHANVTR--LDHPWSACSD-VLTRWVDSAKTVLPI 408
Query: 391 YTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLD----NQVGGRIV 446
+L+K +++W+YSGD DGRVPV +R V L LP+ + WR W+ +VGG IV
Sbjct: 409 IQELMKNSIRVWVYSGDTDGRVPVTSSRLSVNQLQLPVAAKWRPWFSSTKGAGEVGGYIV 468
Query: 447 EYEG-LTYVTVRGAGHLVPLNKPKEALSLIHSFLAGDRLP 485
+Y+G L+ VTVRGAGH VP +P+ AL L+ +FLAG LP
Sbjct: 469 QYKGDLSLVTVRGAGHEVPSYQPRRALVLVQNFLAGKALP 508
>NF31_NAEFO (P42661) Virulence-related protein Nf314 (EC 3.4.16.-)
Length = 482
Score = 281 bits (720), Expect = 2e-75
Identities = 178/478 (37%), Positives = 256/478 (53%), Gaps = 44/478 (9%)
Query: 42 GANESDRIV-DLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNG 100
G D +V LPG+ + V ++GY+ N GR LFYWFFE+ PS+ PL++W NG
Sbjct: 8 GQTAQDHLVTQLPGLSGNIGVKSYTGYLLANATRGRYLFYWFFESMRNPSQDPLVMWTNG 67
Query: 101 GPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDL 160
GPGCSS+G G A E G LVN +G + NPYSWN+ +N+L++E PVGVGFSY+N++ D
Sbjct: 68 GPGCSSLG-GEASEHGLFLVNADGATITRNPYSWNRVSNILYIEQPVGVGFSYSNSTDDY 126
Query: 161 TILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKY 220
L D A D N L ++L RFPQF R +++GESYGG Y+P A I + N K +
Sbjct: 127 QNLNDVQAASDMNNALRDFLTRFPQFIGRETYLAGESYGGVYVPTTAYNIVEGN-GKGQQ 185
Query: 221 PFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVC--DFKQFQWSNECN 278
P++NL G +VGN T+ D + H++IS + Y++ + C DF Q C
Sbjct: 186 PYVNLVGILVGNGVTDAEADSNSIPPMMKYHSLISIKYYEEGYKACQGDFYANQNLPACQ 245
Query: 279 KAMNEVFQDYSEIDIYNIYAP--------KCRLNSTSAIASEGLEQLTK----------- 319
K + + I+ Y IY + +L +T + + L+ T+
Sbjct: 246 KFLTDSSNAMGNINPYYIYDSCPWLGINLQQKLKTTQEMTFQVLDPKTQQPVKIHPLFQM 305
Query: 320 ---GRNDYRMKRKRIFGGY----DPCYSTYA-EKYFNRIDVQSSFHVNTERGNTNITWEV 371
G R+ +R F PC + KYF R+DVQ + V + + N W +
Sbjct: 306 YKHGGWSKRVANERNFAPRFETDAPCVPNQSIAKYFRRLDVQQALGVRRKTADPN-GWNI 364
Query: 372 CNNSILQTYNFSVFSILPIYTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSS 431
C I T +S +ILP Y KL+ ++I +YSGD D V +GT+ ++ L L SS
Sbjct: 365 CTGIINYTQVYS--TILPFYAKLLP-HIRILVYSGDTDMVVNGLGTQAAIDKLQLQETSS 421
Query: 432 WRSWYLDNQ----VGGRIVEYE----GLTYVTVRGAGHLVPLNKPKEALSLIHSFLAG 481
WR+W D+ VGG I ++E GLT++TVRGAGH+VPL KP A + +F+ G
Sbjct: 422 WRTWEFDSALGTVVGGYIRKFEKSGKGLTFITVRGAGHMVPLVKPDSAFYMFKNFIDG 479
>CP21_HORVU (P55747) Serine carboxypeptidase II-1 precursor (EC
3.4.16.6) (CP-MII.1) (Fragment)
Length = 324
Score = 280 bits (717), Expect = 5e-75
Identities = 142/329 (43%), Positives = 197/329 (59%), Gaps = 16/329 (4%)
Query: 158 SDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDK 217
SDL DN A D+Y FLVNWL+RFPQ+K R F+I+GESY GHY+PQL++L+ NK
Sbjct: 2 SDLLTPGDNKTAHDSYAFLVNWLERFPQYKYRDFYIAGESYAGHYVPQLSQLVHRNNKGV 61
Query: 218 NKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQWSNE- 276
K P +N KGF+VGN +DY+D+ G EY W+H +ISD Y K + C+F + +E
Sbjct: 62 RK-PILNFKGFMVGNAVIDDYHDFVGTFEYWWTHGLISDDTYQKLQLACEFDSAEHESEA 120
Query: 277 CNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFGGYD 336
CNK N + ID Y+IY P C+ S +L KGR + + GYD
Sbjct: 121 CNKINNVAEAEEGLIDAYSIYTPTCKKTSLHR------RRLIKGRRPWLPR------GYD 168
Query: 337 PCYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIK 396
PC Y+ KY+N +VQ +F N +W C++ + + S S+LPIY +LI
Sbjct: 169 PCTEQYSTKYYNLPEVQKAFRANVT--GIPYSWTACSDVLSDHWKDSPRSMLPIYRELIA 226
Query: 397 GGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLDNQVGGRIVEYEGLTYVTV 456
G++IW++SGDAD VP+ TRY ++AL LP ++W WY + +V G Y+GLT VT+
Sbjct: 227 AGIRIWVFSGDADSVVPLTATRYSIDALYLPTVTNWYPWYDEEEVAGWCQVYKGLTLVTI 286
Query: 457 RGAGHLVPLNKPKEALSLIHSFLAGDRLP 485
RGAGH VPL++P++AL L FL +P
Sbjct: 287 RGAGHEVPLHRPQQALKLFEHFLQDKPMP 315
>CBP1_ORYSA (P37890) Serine carboxypeptidase I precursor (EC
3.4.16.5) (Carboxypeptidase C)
Length = 510
Score = 254 bits (649), Expect = 4e-67
Identities = 160/487 (32%), Positives = 249/487 (50%), Gaps = 48/487 (9%)
Query: 38 GINVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLW 97
G+ A S + +PG + H++GY+TV E HGR LFY+ E++ +P+K PL+LW
Sbjct: 32 GVCEAAPASAVVKSVPGFDGALPSKHYAGYVTVEEQHGRNLFYYLVESERDPAKDPLVLW 91
Query: 98 LNGGPGCSSVGYGAAIEIGPLLVNKNGEG-----LNFNPYSWNQEANLLFVESPVGVGFS 152
LNGGPGCSS G E GP G L+ NPYSW++ +++++++SP GVG S
Sbjct: 92 LNGGPGCSSFD-GFVYEHGPFNFESGGSAKSLPKLHLNPYSWSKVSSVIYLDSPAGVGLS 150
Query: 153 YTNTSSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFD 212
Y+ +SD D A D++ FL+ W Q +P+F S F+I+GESY G Y+P L+ +
Sbjct: 151 YSKNTSDYN-TGDLKTAADSHTFLLKWFQLYPEFLSNPFYIAGESYAGVYVPTLSHEVVK 209
Query: 213 RNKDKNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQ 272
D K P IN KG++VGN + +D L+ +A A+ISD Y +A+ C +
Sbjct: 210 GLHDGVK-PTINFKGYMVGNGVCDTVFDGNALVPFAHGMALISDDIYQEAQTACHGNYWN 268
Query: 273 -WSNECNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDY------- 324
+++C A+ +V ++++IY+I P C + T + +L K
Sbjct: 269 TTTDKCENALYKVDTSINDLNIYDILEP-CYHSKTIKKVTPANTKLPKSFQHLGTTTKPL 327
Query: 325 ----RMK------RKRIFGGYDPCYSTYAE----------------KYFNRIDVQSSFHV 358
RM R + G P + +A + N DV+++ H
Sbjct: 328 AVRTRMHGRAWPLRAPVRAGRVPSWQEFARGSRPSGVPCMSDEVATAWLNNDDVRAAIH- 386
Query: 359 NTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIKGGLKIWIYSGDADGRVPVIGTR 418
+ ++ +W +C N + + S++ + L G + +IYSGD D VP GT
Sbjct: 387 -AQPVSSIGSWLICTNVL--DFIHDAGSMISYHKNLTGQGYRAFIYSGDHDMCVPYTGTE 443
Query: 419 YCVEALGLPLKSSWRSWYLDNQVGGRIVEYE-GLTYVTVRGAGHLVPLNKPKEALSLIHS 477
+LG + SWR W+L+ QV G YE GLT+ T++GAGH VP KP+E+L+
Sbjct: 444 AWTRSLGYGVIDSWRPWHLNGQVSGYTQGYEHGLTFATIKGAGHTVPEYKPQESLAFYSR 503
Query: 478 FLAGDRL 484
+LAG +L
Sbjct: 504 WLAGSKL 510
>YSS2_CAEEL (Q09991) Putative serine carboxypeptidase K10B2.2
precursor (EC 3.4.16.-)
Length = 470
Score = 246 bits (629), Expect = 7e-65
Identities = 146/465 (31%), Positives = 244/465 (52%), Gaps = 33/465 (7%)
Query: 33 FIKTYGINVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKK 92
F+ +Y + A +D++ DLPG+ +P H+SGY+ D + L YW E+ P++
Sbjct: 10 FVSSYSFCLAAPATDKVNDLPGLTFTPDFFHYSGYLRAWTD--KYLHYWLTESSRAPTQD 67
Query: 93 PLLLWLNGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFS 152
PL+LWLNGGPGCSS+ G E+GP V G + +N Y+WN+ AN+LF+ESP GVG+S
Sbjct: 68 PLVLWLNGGPGCSSLD-GLIEELGPFHVKDFGNSIYYNEYAWNKFANVLFLESPAGVGYS 126
Query: 153 YTNTSSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFD 212
Y +T+ +LT+ +D V+ Y L+++L +FP++K R F+I+GESY G YIP LA I +
Sbjct: 127 Y-STNFNLTVSDDE-VSLHNYMALLDFLSKFPEYKGRDFWITGESYAGVYIPTLAVRILN 184
Query: 213 RNKDKNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQ-------- 264
DK +P N KG +GN +Y ++ + + HA++ D Y+ +
Sbjct: 185 ---DKKNFP--NFKGVAIGNGALNFPNNYNTMVPFYYYHALVRDDLYNDIARNCCNNNIG 239
Query: 265 VCDFKQFQWSNECNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDY 324
CD + C + +E+++YN+Y C N T+ + +E+ +
Sbjct: 240 TCDIYSKFFDPNCRDKVINALDGTNELNMYNLY-DVCYYNPTTNLKKAFIERQMRIAVGL 298
Query: 325 RMKRKRIFGGYDPCYST-YAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFS 383
++ C T Y NR DV+ S H+ + WE C++ + + Y +
Sbjct: 299 PARKHNAATTVPLCAQTNNTHVYLNRADVRKSLHIPSSLP----AWEECSDQVGKNYVVT 354
Query: 384 VFSILPIYTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSW----RSWYLDN 439
F+++P + +I G+KI +Y+GD D I + + +L L + +W+
Sbjct: 355 HFNVIPEFQTMIAAGIKILVYNGDVDTACNSIMNQQFLTSLNLTVLGEQEKVNEAWHYSG 414
Query: 440 QVGGRIVEYE-----GLTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
Q G + ++ + ++TVRG+GH VP +KPKE+ +I +F+
Sbjct: 415 QTGTAVAGFQTKFAGNVDFLTVRGSGHFVPEDKPKESQQMIFNFI 459
>CBP1_HORVU (P07519) Serine carboxypeptidase I precursor (EC
3.4.16.5) (Carboxypeptidase C) (CP-MI)
Length = 499
Score = 236 bits (603), Expect = 8e-62
Identities = 147/477 (30%), Positives = 242/477 (49%), Gaps = 43/477 (9%)
Query: 43 ANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGP 102
A + + LPG + H++GY+TV+E HGR LFY+ E++ +P K P++LWLNGGP
Sbjct: 31 APQGAEVTGLPGFDGALPSKHYAGYVTVDEGHGRNLFYYVVESERDPGKDPVVLWLNGGP 90
Query: 103 GCSSVGYGAAIEIGPLLVNKNGE-----GLNFNPYSWNQEANLLFVESPVGVGFSYTNTS 157
GCSS G E GP G L+ NPY+W++ + +++++SP GVG SY+
Sbjct: 91 GCSSFD-GFVYEHGPFNFESGGSVKSLPKLHLNPYAWSKVSTMIYLDSPAGVGLSYSKNV 149
Query: 158 SDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDK 217
SD D A D++ FL+ W Q +P+F S F+I+GESY G Y+P L+ + +
Sbjct: 150 SDYE-TGDLKTATDSHTFLLKWFQLYPEFLSNPFYIAGESYAGVYVPTLSHEVVKGIQGG 208
Query: 218 NKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQWSN-E 276
K P IN KG++VGN + +D L+ +A +ISD+ Y +A C + ++ +
Sbjct: 209 AK-PTINFKGYMVGNGVCDTIFDGNALVPFAHGMGLISDEIYQQASTSCHGNYWNATDGK 267
Query: 277 CNKAMNEVFQDYSEIDIYNIYAPKC-------RLNSTSAIASEGLEQLTKGRNDYRMKRK 329
C+ A++++ S ++IY+I P C +N ++ + + L + ++ +
Sbjct: 268 CDTAISKIESLISGLNIYDILEP-CYHSRSIKEVNLQNSKLPQSFKDLGTTNKPFPVRTR 326
Query: 330 RIFGGYD--------------------PCYS-TYAEKYFNRIDVQSSFHVNTERGNTNIT 368
+ + PC S A + + V+S+ H + +
Sbjct: 327 MLGRAWPLRAPVKAGRVPSWQEVASGVPCMSDEVATAWLDNAAVRSAIHAQSV--SAIGP 384
Query: 369 WEVCNNSILQTYNFSVFSILPIYTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPL 428
W +C + + ++ S++ + L G + I+SGD D VP G+ ++LG +
Sbjct: 385 WLLCTDKLYFVHDAG--SMIAYHKNLTSQGYRAIIFSGDHDMCVPFTGSEAWTKSLGYGV 442
Query: 429 KSSWRSWYLDNQVGGRIVEYE-GLTYVTVRGAGHLVPLNKPKEALSLIHSFLAGDRL 484
SWR W + QV G YE GLT+ T++GAGH VP KP+EA + +LAG +L
Sbjct: 443 VDSWRPWITNGQVSGYTEGYEHGLTFATIKGAGHTVPEYKPQEAFAFYSRWLAGSKL 499
>YUW5_CAEEL (P52717) Putative serine carboxypeptidase F41C3.5
precursor (EC 3.4.16.-)
Length = 469
Score = 228 bits (581), Expect = 3e-59
Identities = 142/472 (30%), Positives = 230/472 (48%), Gaps = 51/472 (10%)
Query: 41 VGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNG 100
VG + I DLPG+ P+ H+SG+ V+++H L YWF E+Q+EPS PL+ W NG
Sbjct: 11 VGVTCGEEIKDLPGLDFEPNFKHYSGFFQVSDNH--VLHYWFVESQNEPSNDPLIFWFNG 68
Query: 101 GPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYT-----N 155
GPGCSS+ G E+GP + N++G+ L N YSWN+ A+++++ESP GVG+SY
Sbjct: 69 GPGCSSLD-GLLNEMGPYVANEDGKTLRENEYSWNKMASVVYIESPAGVGYSYATDGNIT 127
Query: 156 TSSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNK 215
T+ DLT LE+ Y + + FPQF+ FI GESYGG Y+P L I D K
Sbjct: 128 TNDDLTSLEN-------YEAVKQFFTEFPQFRHHQTFIMGESYGGVYVPTLTARIVDGQK 180
Query: 216 DKNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVC------DFK 269
D +P INLKG +GN + + + +A+ H +I ++ ++ ++ C
Sbjct: 181 D---FP-INLKGMALGNGYVNEKLNIDTSVRFAYGHGLIDEKIWNTLERDCCRGCIDSCD 236
Query: 270 QFQWSNECNKAMNEVFQ-----DYSEIDIYNIYAPKCRLNSTS--------AIASEGLEQ 316
Q + C + ++FQ + D+Y P +NS A A ++
Sbjct: 237 LTQVTGHCATLVEDIFQFLWFGGLNPYDLYRDCDPNPSVNSKRMKHMLRGVAPAMAHFDE 296
Query: 317 LTKGRN--------DYRMKRKRIFGGYDPCYS-TYAEKYFNRIDVQSSFHVNTERGNTNI 367
L K + + + ++ PC + T Y N V+ + H+ G
Sbjct: 297 LLKNQTKTSLYQFLKNKSQSQKPLKADVPCLNDTEMLSYMNNPKVRKAIHIPFNLGK--- 353
Query: 368 TWEVCNNSILQTYNFSVFSILPIYTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLP 427
W++C++ + TY + P K++K +++ +Y GD D + + + LGL
Sbjct: 354 -WDICSDKVTTTYQKQYTDMTPFIKKIVKNHVRVLLYYGDTDMACNFMMGQQFSDQLGLR 412
Query: 428 LKSSWRSWYLDNQVGGRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
W D Q+ G ++GL+++T+RGAGH+ P + + + FL
Sbjct: 413 RTLKKTPWKYDRQIAGFKTLFDGLSFITIRGAGHMAPQWRAPQMYYAVQQFL 464
>YUA6_CAEEL (P52715) Putative serine carboxypeptidase F13S12.6
precursor (EC 3.4.16.-)
Length = 454
Score = 226 bits (575), Expect = 1e-58
Identities = 145/449 (32%), Positives = 218/449 (48%), Gaps = 33/449 (7%)
Query: 45 ESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGPGC 104
ES I +LPG P S + +SGY V L YWF E+QS PS P+LLWL GGPGC
Sbjct: 20 ESALITNLPGAPIS-NFKQYSGYYNVGTKKNHMLHYWFVESQSNPSTDPVLLWLTGGPGC 78
Query: 105 SSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILE 164
S + E GP VN +G L NPYSWN+ A++L +E+P GVG+SY ++ T
Sbjct: 79 SGLS-ALLTEWGPWNVNTDGATLRTNPYSWNKNASILTLEAPAGVGYSYATDNNIAT--G 135
Query: 165 DNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPFIN 224
D+ A + + LV + FPQ+K F+++GESYGG Y+P L + I DR + IN
Sbjct: 136 DDQTASENWEALVAFFNEFPQYKGNDFYVTGESYGGIYVPTLVQTILDRQSQSH----IN 191
Query: 225 LKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVC-----------DFKQFQW 273
+KG +GN L+ + + H V+ +++ K C F +F
Sbjct: 192 IKGLAIGNGCVSANEGVDSLVNFLYHHGVVDQAKWEHMKTSCCHNDTDACPWHSFSEFSA 251
Query: 274 SNECNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFG 333
E +A + + ++ YN+YA STSA G+E + Y + G
Sbjct: 252 CGEFVEATQQTAWN-GGLNPYNMYAD---CISTSASFRFGMEYERRFNKKY---TPEVLG 304
Query: 334 GYDPCYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILP-IYT 392
+ Y NR DV+ + + + W +C+N+I Y + +
Sbjct: 305 TVPCLDESPVTNYLNRQDVRKALGIPSSLP----AWSICSNAISYGYKRQYGDMTSRVLN 360
Query: 393 KLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLDNQVGGRIVEYEG-- 450
+ LK+ +Y+GD D + + + LGL L + + Q+GG + +Y+G
Sbjct: 361 AVNNNNLKMMLYNGDVDLACNALMGQRFTDKLGLTLSKKKTHFTVKGQIGGYVTQYKGSQ 420
Query: 451 LTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
+T+ TVRGAGH+VP +KP A +I SFL
Sbjct: 421 VTFATVRGAGHMVPTDKPAVAEHIIQSFL 449
>PRTP_MOUSE (P16675) Lysosomal protective protein precursor (EC
3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective
protein for beta-galactosidase)
Length = 474
Score = 225 bits (574), Expect = 2e-58
Identities = 150/474 (31%), Positives = 237/474 (49%), Gaps = 59/474 (12%)
Query: 40 NVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLN 99
N A + D I LPG+ PS +SGY+ ++ + YWF E+Q++P P++LWLN
Sbjct: 21 NEAAPDQDEIDCLPGLAKQPSFRQYSGYLRASDS--KHFHYWFVESQNDPKNSPVVLWLN 78
Query: 100 GGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSD 159
GGPGCSS+ G E GP L+ +G L +NPY+WN AN+L++ESP GVGFSY++
Sbjct: 79 GGPGCSSLD-GLLTEHGPFLIQPDGVTLEYNPYAWNLIANVLYIESPAGVGFSYSD--DK 135
Query: 160 LTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNK 219
+ + D VAE+ Y L ++ + FP++K F++GESY G YIP LA L+ +
Sbjct: 136 MYVTNDTEVAENNYEALKDFFRLFPEYKDNKLFLTGESYAGIYIPTLAVLVM-------Q 188
Query: 220 YPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISD------QQYDKAKQVCDFKQFQW 273
P +NL+G VGN + L+ +A+ H ++ + Q + A+ C+F +
Sbjct: 189 DPSMNLQGLAVGNGLASYEQNDNSLVYFAYYHGLLGNRLWTSLQTHCCAQNKCNFYDNK- 247
Query: 274 SNECNKAMNEVFQ--DYSEIDIYNIYAP-------KCRLNSTSAIASEG----------- 313
EC + EV + S ++IYN+YAP + R T + G
Sbjct: 248 DPECVNNLLEVSRIVGKSGLNIYNLYAPCAGGVPGRHRYEDTLVVQDFGNIFTRLPLKRR 307
Query: 314 -LEQLTKGRNDYRMKRKRIFGGYDPCYSTYA-EKYFNRIDVQSSFHVNTERGNTNITWEV 371
E L + + R+ PC +T A Y N V+ + H+ W++
Sbjct: 308 FPEALMRSGDKVRLD--------PPCTNTTAPSNYLNNPYVRKALHIPESLPR----WDM 355
Query: 372 CNNSILQTYNFSVFSILPIYTKLIKG-GLKIWIYSGDADGRVPVIGTRYCVEALGLPLKS 430
CN + Y S+ Y KL+ +I +Y+GD D +G + V++L ++
Sbjct: 356 CNFLVNLQYRRLYQSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEV 415
Query: 431 SWRSWYLD-----NQVGGRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
R W +D QV G + E +T++T++GAGH+VP +KP+ A ++ FL
Sbjct: 416 QRRPWLVDYGESGEQVAGFVKECSHITFLTIKGAGHMVPTDKPRAAFTMFSRFL 469
>PRTP_HUMAN (P10619) Lysosomal protective protein precursor (EC
3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective
protein for beta-galactosidase)
Length = 480
Score = 213 bits (543), Expect = 7e-55
Identities = 145/465 (31%), Positives = 232/465 (49%), Gaps = 46/465 (9%)
Query: 43 ANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGP 102
A + D I LPG+ PS +SGY+ + L YWF E+Q +P P++LWLNGGP
Sbjct: 29 APDQDEIQRLPGLAKQPSFRQYSGYL--KGSGSKHLHYWFVESQKDPENSPVVLWLNGGP 86
Query: 103 GCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTI 162
GCSS+ G E GP LV +G L +NPYSWN AN+L++ESP GVGFSY++ T
Sbjct: 87 GCSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYAT- 144
Query: 163 LEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPF 222
D VA+ + L ++ + FP++K+ F++GESY G YIP LA L+ P
Sbjct: 145 -NDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQD-------PS 196
Query: 223 INLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDK------AKQVCDFKQFQWSNE 276
+NL+G VGN + + L+ +A+ H ++ ++ + ++ C+F + E
Sbjct: 197 MNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNK-DLE 255
Query: 277 CNKAMNEVFQ--DYSEIDIYNIYAPKCRLNSTS-------AIASEGLEQLTKGRNDYRMK 327
C + EV + S ++IYN+YAP C S + + L + RM
Sbjct: 256 CVTNLQEVARIVGNSGLNIYNLYAP-CAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMW 314
Query: 328 RKRIFGGYD------PCYSTYAEK-YFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTY 380
+ + D PC +T A Y N V+ + ++ + W++CN + Y
Sbjct: 315 HQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQ----WDMCNFLVNLQY 370
Query: 381 NFSVFSILPIYTKLIKGG-LKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSWRSWYLD- 438
S+ Y KL+ +I +Y+GD D +G + V++L ++ R W +
Sbjct: 371 RRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKY 430
Query: 439 ----NQVGGRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
Q+ G + E+ + ++T++GAGH+VP +KP A ++ FL
Sbjct: 431 GDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFL 475
>YXD2_CAEEL (P52714) Putative serine carboxypeptidase C08H9.1 (EC
3.4.16.-)
Length = 505
Score = 209 bits (532), Expect = 1e-53
Identities = 148/483 (30%), Positives = 228/483 (46%), Gaps = 64/483 (13%)
Query: 50 VDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEP-SKKPLLLWLNGGPGCSSVG 108
+ LPG P + SGY+ NE+ + +FY+ EA+ P + L++W NGGPGCSS+
Sbjct: 24 IHLPGNSDIPDLKLQSGYLNANENGTQKMFYFLLEARDIPVGEASLIIWFNGGPGCSSLS 83
Query: 109 YGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILEDNFV 168
E GPL VN G+ L N +SW +AN+LF+ESP+GVGFSY S+ T + D+ +
Sbjct: 84 -AFFEEFGPLYVNFGGKSLFENVHSWYHKANILFLESPIGVGFSYDTEQSNFTKVNDDSI 142
Query: 169 AEDAYNFLVNWLQR-FPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPFINLKG 227
AE +N ++++ QR + + FFI+ ESYGG Y P L+ L+ D + K ++P N KG
Sbjct: 143 AEQNFNSVIDFFQRKHSSYVNHDFFIAAESYGGVYGPMLSALVVD-SISKREFPNENFKG 201
Query: 228 FIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVC-----------DFKQFQW--- 273
I+GN ++ ++ H S ++D+ K+ C DF QF
Sbjct: 202 LIIGNGFMNVKLSTNTMILWSAYHDRTSPDEWDEIKEKCATSGAHDVDYYDFMQFMKTTN 261
Query: 274 --------SNECNKAMNEVFQDYSE----IDIYNIYAPKCRLNSTSAIAS----EGLEQL 317
S EC + + + +SE D +N Y C N + A+ E L Q+
Sbjct: 262 KMDYLADNSTECGRLIEPLLGQFSETFDGYDFFNYY-HDCYTNFSIPNATDPIKETLAQI 320
Query: 318 TKGRNDYRMKRKRIFGGYDPCYSTYAE----KYFNRIDVQSSFHVNTERGNTNITWEVCN 373
+ R + G Y +A+ KY N +VQ++ ++ + WEVCN
Sbjct: 321 PRRRISALFNKHSTDG--QASYRCWADDALHKYLNLKEVQNALGIDRAWKDRKKKWEVCN 378
Query: 374 NSILQTYNFSVFSILPIYTKLIK----GGLKIWIYSGDADGRVPVIGTRYCVEALGLPLK 429
I Y + + P ++K+ ++ IYSGD D + Y G
Sbjct: 379 MPIYDQYVMTHQDMTPFFSKIFDKFTGPAFRVLIYSGDIDTACNYLADGYFTLKHG---- 434
Query: 430 SSWRSWYLDNQ--VGGRIVEYEGLTY---------VTVRGAGHLVPLNKPKEALSLIHSF 478
WY + G + YEG + VTV+G+GH VPL++P AL ++H+F
Sbjct: 435 ----PWYHSEHKVIAGNFMRYEGANHLGSKLSIDVVTVKGSGHFVPLDRPGPALQMVHNF 490
Query: 479 LAG 481
L G
Sbjct: 491 LTG 493
>YPP3_CAEEL (P52716) Putative serine carboxypeptidase F32A5.3
precursor (EC 3.4.16.-)
Length = 574
Score = 184 bits (468), Expect = 3e-46
Identities = 154/534 (28%), Positives = 238/534 (43%), Gaps = 87/534 (16%)
Query: 24 LCFFLLTTSFIKTYGINVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFF 83
+C LL +F+ ++ G E D I +LPG+ + +SGY+ N + + Y
Sbjct: 1 MCRTLLGVAFLVVTVLSQG--EKDLIQNLPGLLFKANFKSYSGYVDANANGTWKMHYMLT 58
Query: 84 EAQSEPSKKPLLLWLNGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFV 143
E++S P PLL+W NGGPGCSS+G G E+GP VN +G+ L NPY+WN +AN+L++
Sbjct: 59 ESRSNPDTDPLLVWFNGGPGCSSLG-GLFEELGPFYVNFDGQTLYENPYAWNAKANVLYL 117
Query: 144 ESPVGVGFSYTNTSSDLTILEDNFVAEDAYNFLVNWLQ-RFPQFKSRGFFISGESYGGHY 202
ESP+GVG+SY T+ D+ A Y L N+ P++ +R F++SGESY G Y
Sbjct: 118 ESPIGVGYSYDTTTPGYFQANDDQSAAQNYQALTNFFNVAQPKYTNRTFYLSGESYAGIY 177
Query: 203 IPQLAELIFDR-NKDKNKYPFINLKGFIVGNPETEDYYDYKGLLE--YAWS--HAVISDQ 257
IP L +LI N +P N +G +GN + + GLL WS H +S+Q
Sbjct: 178 IPMLTDLIVQGINNPNQPFPNKNFQGSAIGN----GFMNVAGLLNALTLWSAYHGRVSEQ 233
Query: 258 QYDKAKQVC---------DFKQFQWSNE----------CNKAMNEVFQDYS----EIDIY 294
+ K C DF QF S C + + + D Y
Sbjct: 234 NWADIKANCSKGADVDSFDFSQFTTSQNKIDYVGDGSYCGNLIQPLISQNALGNEGFDQY 293
Query: 295 NIY----------AP---------KCRLNSTSAIAS----------EGLEQLTKGRNDY- 324
N Y AP + + S++ +G L K
Sbjct: 294 NFYQECYDKSVFQAPPPAGGKRHKRSAMQGVSSVQKNLQYQQLGNFQGTSNLAKNTATLV 353
Query: 325 -RMKRKRIFGGYDPCYSTYA-EKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNF 382
R FG + C++ A KY N +VQ++ ++ + TWE C SI Y
Sbjct: 354 NRFSNDNQFGYF--CWNEDAVSKYLNSDNVQNALNIPQAWKDQKNTWEDCRMSIYNNYTL 411
Query: 383 SVFSILPIYTKLIKG---GLKIWIYSGDADGRVPVIG-TRYCVE-ALGLPLKSSWRS-WY 436
+ + +I + IY+GD D +G ++ ++ A L S R+ WY
Sbjct: 412 KYNTTNRFFNNIITNLTTDFRFLIYNGDVDTVCNYLGDAKHILQVAKDNGLTSGPRTPWY 471
Query: 437 LDN--QVGGRIVEYEG---------LTYVTVRGAGHLVPLNKPKEALSLIHSFL 479
N Q+ G + Y G + +TV+GAGH+VP ++ ++ +I +F+
Sbjct: 472 YSNNQQLAGYVQTYSGKNKNNAMITIDLLTVKGAGHMVPYDRAGPSVQMISNFV 525
>CBPY_SCHPO (O13849) Carboxypeptidase Y precursor (EC 3.4.16.5)
(CPY)
Length = 1002
Score = 180 bits (457), Expect = 6e-45
Identities = 131/449 (29%), Positives = 222/449 (49%), Gaps = 62/449 (13%)
Query: 60 SVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGPGCSSVGYGAAIEIGPLL 119
+V ++GY+ V +D R LF+WFFE++++P P++LWLNGGPGCSS+ G +E+GP
Sbjct: 585 TVKQYTGYLDVEDD--RHLFFWFFESRNDPENDPVVLWLNGGPGCSSL-TGLFMELGPSS 641
Query: 120 VNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILEDNFVAEDAYNFLVNW 179
+N +NP+SWN A+++F++ P+ GFS + D ++L+ +D Y FL +
Sbjct: 642 INIETLKPEYNPHSWNSNASVIFLDQPINTGFS----NGDDSVLDTVTAGKDVYAFLNLF 697
Query: 180 LQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKY---------PFINLKGFIV 230
+FPQ+ F I+GESY GHYIPQ A+ I + N+ N + +INLK ++
Sbjct: 698 FAKFPQYAHLDFHIAGESYAGHYIPQFAKEIMEHNQGANFFVASGYEMEKQYINLKSVLI 757
Query: 231 GNPETE---DYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQWSNECNKAMNEVFQD 287
GN T+ YY Y + + ++S ++ D+ D C K + +Q
Sbjct: 758 GNGLTDPLVQYYFYGKMACESPYGPIMSQEECDRITGAYD--------TCAKLITGCYQ- 808
Query: 288 YSEIDIYNIYAPKCRLNSTSAIASEGLEQLTK-GRNDYRMKRKRIFGGYDPCY--STYAE 344
+ P C + ++ + + TK G N Y + R+ CY + E
Sbjct: 809 -------TGFTPVC-IGASLYCNNAMIGPFTKTGLNIYDI-REECRDQEHLCYPETGAIE 859
Query: 345 KYFNRIDVQSSFHV-------NTERGNTNITWEVCNNSILQTYNFSVFSILPIYTKLIKG 397
Y N+ VQ + V NTE NI + + + +T+ V T +++
Sbjct: 860 SYLNQEFVQEALGVEYDYKGCNTE---VNIGFLFKGDWMRKTFRDDV-------TAILEA 909
Query: 398 GLKIWIYSGDADGRVPVIGTRYCVEALGLP-----LKSSWRSWYLDNQVGGRIVEYEGLT 452
GL + IY+GDAD +G +AL ++ + W + + GR ++
Sbjct: 910 GLPVLIYAGDADYICNYMGNEAWTDALEWAGQREFYEAELKPWSPNGKEAGRGKSFKNFG 969
Query: 453 YVTVRGAGHLVPLNKPKEALSLIHSFLAG 481
Y+ + AGH+VP N+P+ +L +++S++ G
Sbjct: 970 YLRLYEAGHMVPFNQPEASLEMLNSWIDG 998
>YBY9_YEAST (P38109) Putative serine carboxypeptidase in ESR1-IRA1
intergenic region (EC 3.4.16.-)
Length = 508
Score = 179 bits (455), Expect = 1e-44
Identities = 130/467 (27%), Positives = 225/467 (47%), Gaps = 80/467 (17%)
Query: 48 RIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKKPLLLWLNGGPGCSSV 107
R VD P +V +SGY+ + + FYWFFE++++P+ P++LWLNGGPGCSS
Sbjct: 79 RTVD-PSKLGIDTVKQWSGYMDYKDS--KHFFYWFFESRNDPANDPIILWLNGGPGCSSF 135
Query: 108 GYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILEDNF 167
G E+GP + + + ++ NPYSWN A+++F+E P+GVGFSY D +
Sbjct: 136 T-GLLFELGPSSIGADMKPIH-NPYSWNNNASMIFLEQPLGVGFSY----GDEKVSSTKL 189
Query: 168 VAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPFINLKG 227
+DAY FL + + FP +S F I+GESY GHYIPQ+A I +N ++ NL
Sbjct: 190 AGKDAYIFLELFFEAFPHLRSNDFHIAGESYAGHYIPQIAHEIVVKNPERT----FNLTS 245
Query: 228 FIVGNPETE-----DYYDYKGLLEYAWSHAVISDQQYDKAKQVCD----FKQFQWSNE-- 276
++GN T+ DYY+ + + H V+S ++ +K + + ++++
Sbjct: 246 VMIGNGITDPLIQADYYEPMACGKGGY-HPVLSSEECEKMSKAAGRCRRLNKLCYASKSS 304
Query: 277 ---------CNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMK 327
C+ A+ E + + + +++Y+I P C NST + GL
Sbjct: 305 LPCIVATAYCDSALLEPYIN-TGLNVYDIRGP-CEDNSTDGMCYTGLR------------ 350
Query: 328 RKRIFGGYDPCYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSI 387
Y ++Y N +VQ + G+ + C+N + + F+
Sbjct: 351 --------------YVDQYMNFPEVQETL------GSDVHNYSGCDNDVFTGFLFTGDGS 390
Query: 388 LPIY---TKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSSW-----RSWYLDN 439
P +L+ + + IY+GD D +G L K + R W +
Sbjct: 391 KPFQQYIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPW-VSK 449
Query: 440 QVG---GRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFLAGDR 483
+ G G++ Y T++ + AGH+VP ++P+ +L +++S+++G+R
Sbjct: 450 ETGEELGQVKNYGPFTFLRIYDAGHMVPYDQPEASLEMVNSWISGNR 496
>CBP3_HORVU (P21529) Serine carboxypeptidase III precursor (EC
3.4.16.5) (CP-MIII)
Length = 508
Score = 179 bits (455), Expect = 1e-44
Identities = 133/464 (28%), Positives = 217/464 (46%), Gaps = 52/464 (11%)
Query: 37 YGINVGANESD--------RIVDLPGVPSSPS-VSHFSGYITVNEDHGRALFYWFFEAQS 87
+G VG D R V LPG+P + + H +GY + H +FY+FFE++
Sbjct: 58 HGARVGEGNEDVAPGQLLERRVTLPGLPEGVADLGHHAGYYRLPNTHDARMFYFFFESRG 117
Query: 88 EPSKKPLLLWLNGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPV 147
+ + P+++WL GGPGCSS E GP + N L +N + W++ +N++FV+ P
Sbjct: 118 K-KEDPVVIWLTGGPGCSSE-LAVFYENGPFTI-ANNMSLVWNKFGWDKISNIIFVDQPT 174
Query: 148 GVGFSYTNTSSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLA 207
G GFSY++ D T ++ V+ D Y+FL + ++ P+F FFI+GESY GHYIP A
Sbjct: 175 GTGFSYSSDDRD-TRHDETGVSNDLYDFLQVFFKKHPEFIKNDFFITGESYAGHYIPAFA 233
Query: 208 ELIFDRNKDKNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQV-- 265
+ NK KN+ INLKGF +GN T+ YK +YA +I Y++ +
Sbjct: 234 SRVHQGNK-KNEGTHINLKGFAIGNGLTDPAIQYKAYTDYALEMNLIQKADYERINKFIP 292
Query: 266 -CDFKQFQWSNECNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDY 324
C+F + + + I NS + G +Y
Sbjct: 293 PCEFAIKLCGTNGKASCMAAYMVCNTI-----------FNSIMKLV---------GTKNY 332
Query: 325 RMKRKRIFGGYDPCYS-TYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTYNFS 383
RK G CY + EK+F V+ + V +I + C+ S+ Q
Sbjct: 333 YDVRKECEGKL--CYDFSNLEKFFGDKAVRQAIGVG------DIEFVSCSTSVYQAMLTD 384
Query: 384 VFSILPI-YTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLP-----LKSSWRSWYL 437
L + L++ G+ + IY+G+ D +G V ++ K++ S+ +
Sbjct: 385 WMRNLEVGIPALLEDGINVLIYAGEYDLICNWLGNSRWVHSMEWSGQKDFAKTAESSFLV 444
Query: 438 DNQVGGRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFLAG 481
D+ G + + L+++ V AGH+VP+++PK AL ++ F G
Sbjct: 445 DDAQAGVLKSHGALSFLKVHNAGHMVPMDQPKAALEMLRRFTQG 488
>CPVL_HUMAN (Q9H3G5) Probable serine carboxypeptidase CPVL precursor
(EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like)
(Vitellogenic carboxypeptidase-like protein) (VCP-like
protein)
Length = 476
Score = 174 bits (441), Expect = 5e-43
Identities = 126/461 (27%), Positives = 228/461 (49%), Gaps = 48/461 (10%)
Query: 33 FIKTYGINVGANESDRIVDLPGVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQSEPSKK 92
F+ Y I G + R + L G ++ ++G++TVN+ + LF+WFF AQ +P
Sbjct: 44 FLTPY-IEAGKIQKGRELSLVGPFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQPEDA 102
Query: 93 PLLLWLNGGPGCSSVGYGAAIEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFS 152
P++LWL GGPG SS+ +G +E GP +V N L + W ++L++++PVG GFS
Sbjct: 103 PVVLWLQGGPGGSSM-FGLFVEHGPYVVTSNMT-LRDRDFPWTTTLSMLYIDNPVGTGFS 160
Query: 153 YTNTSSDLTILEDNFVAEDAYNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFD 212
+T+ + + ED+ VA D Y+ L+ + Q FP++K+ F+++GESY G Y+P +A LI
Sbjct: 161 FTDDTHGYAVNEDD-VARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHS 219
Query: 213 RNKDKNKYPFINLKGFIVGNPETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQ 272
N + INL G +G+ ++ G E+ + ++ ++Q K FQ
Sbjct: 220 LNPVREVK--INLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQK---------KYFQ 268
Query: 273 WSNECNKAMNEVFQDYSEIDIYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIF 332
+C++ + + + + ++ + I + TS + + +T N Y R
Sbjct: 269 --KQCHECIEHI-RKQNWLEAFEILDKLLDGDLTSDPSY--FQNVTGCSNYYNFLRCT-- 321
Query: 333 GGYDPCYSTYAEKYFNRIDVQSSFHVNTERGNTNITWEVCNNSILQTY--NFSVFSILPI 390
+P Y K+ + +V+ + HV + N + +I++ Y +V S+ P
Sbjct: 322 ---EPEDQLYYVKFLSLPEVRQAIHVGNQTFN--------DGTIVEKYLREDTVQSVKPW 370
Query: 391 YTKLIKGGLKIWIYSGDADGRVPVIGTRYCVEALGLPLKSS----------WRSWYLDNQ 440
T+++ K+ IY+G D V T + + +G+ K S W+ + D++
Sbjct: 371 LTEIMNN-YKVLIYNGQLDIIVAAALTEHSL--MGMDWKGSQEYKKAEKKVWKIFKSDSE 427
Query: 441 VGGRIVEYEGLTYVTVRGAGHLVPLNKPKEALSLIHSFLAG 481
V G I + V +RG GH++P ++P A +I+ F+ G
Sbjct: 428 VAGYIRQAGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYG 468
>CBPX_ORYSA (P52712) Serine carboxypeptidase-like precursor (EC
3.4.16.-)
Length = 429
Score = 172 bits (437), Expect = 1e-42
Identities = 126/437 (28%), Positives = 210/437 (47%), Gaps = 37/437 (8%)
Query: 54 GVPSSPSVSHFSGYITVNEDHGRALFYWFFEAQ-SEPSKKPLLLWLNGGPGCSSVGYGAA 112
G S+ + H +GY + H LFY+FFE++ S+ P+++WL GGPGCSS
Sbjct: 7 GGSSAEDLGHHAGYYRLPNTHDARLFYFFFESRGSKGEDDPVVIWLTGGPGCSSE-LALF 65
Query: 113 IEIGPLLVNKNGEGLNFNPYSWNQEANLLFVESPVGVGFSYTNTSSDLTILEDNFVAEDA 172
E GP + N L +N + W+QE+NL++V+ P G GFSY++ D T ++ V+ D
Sbjct: 66 YENGPFHIADN-MSLVWNDFGWDQESNLIYVDQPTGTGFSYSSNPRD-TRHDEAGVSNDL 123
Query: 173 YNFLVNWLQRFPQFKSRGFFISGESYGGHYIPQLAELIFDRNKDKNKYPFINLKGFIVGN 232
Y FL + P F F+I+GESY GHYIP A ++ NK+ INLKGF +GN
Sbjct: 124 YAFLQAFFTEHPNFAKNDFYITGESYAGHYIPAFASRVYKGNKNSEGI-HINLKGFAIGN 182
Query: 233 PETEDYYDYKGLLEYAWSHAVISDQQYDKAKQVCDFKQFQWSNECNKAMNEVFQDYSEID 292
T+ YK +Y+ +I+ Q+++ ++ C A+ ++ I
Sbjct: 183 GLTDPAIQYKAYTDYSLDMGLITKSQFNRINKIVP--------TCELAI-KLCGTSGTIS 233
Query: 293 IYNIYAPKCRLNSTSAIASEGLEQLTKGRNDYRMKRKRIFGGYDPCYS-TYAEKYFNRID 351
Y C L +S + G+ +Y RK G CY + EK+
Sbjct: 234 CLGAYV-VCNLICSSI-------ETIIGKKNYYDIRKPCVGSL--CYDLSNMEKFLQLKS 283
Query: 352 VQSSFHVNTERGNTNITWEVCNNSILQTYNFSVFSILPI-YTKLIKGGLKIWIYSGDADG 410
V+ S V +I + C+ ++ Q L + +L++ +K+ IY+G+ D
Sbjct: 284 VRESLGVG------DIQFVSCSPTVYQAMLLDWMRNLEVGIPELLENDIKVLIYAGEYDL 337
Query: 411 RVPVIGTRYCVEALGLP-----LKSSWRSWYLDNQVGGRIVEYEGLTYVTVRGAGHLVPL 465
+G V ++ + SS + +D + G + Y L+++ V AGH+VP+
Sbjct: 338 ICNWLGNSRWVNSMEWSGKEAFVSSSEEPFTVDGKEAGILKSYGPLSFLKVHDAGHMVPM 397
Query: 466 NKPKEALSLIHSFLAGD 482
++PK AL ++ + +G+
Sbjct: 398 DQPKVALEMLMRWTSGN 414
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.139 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,391,632
Number of Sequences: 164201
Number of extensions: 3025770
Number of successful extensions: 6710
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 6495
Number of HSP's gapped (non-prelim): 69
length of query: 488
length of database: 59,974,054
effective HSP length: 114
effective length of query: 374
effective length of database: 41,255,140
effective search space: 15429422360
effective search space used: 15429422360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Lotus: description of TM0333b.9