BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0318.6
(172 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z0D2_HUMAN (O76080) Zinc finger A20 domain containing protein 2 ... 122 5e-28
Z0D2_MOUSE (O88878) Zinc finger A20 domain containing protein 2 ... 120 2e-27
RABX_MOUSE (Q9JM13) Rab5 GDP/GTP exchange factor (Rabex-5) 42 5e-04
RABX_BOVIN (O18973) Rab5 GDP/GTP exchange factor (Rabex-5) 38 0.013
RABX_HUMAN (Q9UJ41) Rab5 GDP/GTP exchange factor (Rabex-5) 37 0.023
CEZ2_MOUSE (Q8R554) Zinc finger A20 domain containing protein ? ... 36 0.050
CEZ1_HUMAN (Q6GQQ9) Zinc finger A20 domain containing protein 1 ... 35 0.066
CEZ2_HUMAN (Q8TE49) Zinc finger A20 domain containing protein ? ... 34 0.15
KDGD_MESAU (Q64398) Diacylglycerol kinase, delta (EC 2.7.1.107) ... 33 0.25
LEFB_NPVLD (Q9YMS9) Late expression factor 11 31 1.6
VP10_WTV (P13093) Nonstructural protein Pns10 30 2.1
PYR1_DICDI (P20054) Protein PYR1-3 [Includes: Glutamine-dependen... 30 2.8
ITB1_BOVIN (P53712) Integrin beta-1 (Fibronectin receptor beta s... 29 4.7
Z295_HUMAN (Q9ULJ3) Zinc finger protein 295 (Zinc finger and BTB... 29 6.1
MTA_CARCW (Q8AWG2) Metallothionein A (MT-A) 29 6.1
ITBX_DROME (P11584) Integrin beta-PS precursor (Position-specifi... 29 6.1
ARC2_ENTFA (P59625) Carbamate kinase 2 (EC 2.7.2.2) 29 6.1
RPOA_ADICA (Q85FJ1) DNA-directed RNA polymerase alpha chain (EC ... 28 8.0
RNP_RAT (P00684) Ribonuclease pancreatic precursor (EC 3.1.27.5)... 28 8.0
MT_ICTPU (O93571) Metallothionein (MT) 28 8.0
>Z0D2_HUMAN (O76080) Zinc finger A20 domain containing protein 2
(Zinc finger protein 216)
Length = 213
Score = 122 bits (305), Expect = 5e-28
Identities = 67/203 (33%), Positives = 92/203 (45%), Gaps = 45/203 (22%)
Query: 15 PILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQ------------------DKLAATSVE 56
P+LC CGF+G T MCS CYK+ L +Q+ D + +
Sbjct: 11 PMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRAD 70
Query: 57 NIVNSCSNGNGKQAITADAVNVRVEPVEVKAVTAQISAD--------------------- 95
+N+C G + + V V PV + IS +
Sbjct: 71 TSLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPS 130
Query: 96 ------SSSGESLEVKAKTGPSRCGTCRKRVGLTGFSCKCGNVFCAMHRYSDKHDCPFDY 149
S S E K +RC CRK+VGLTGF C+CGN+FC +HRYSDKH+CP+DY
Sbjct: 131 VSQPSTSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRYSDKHNCPYDY 190
Query: 150 RAVGQEAIAKANPVIKADKLDKI 172
+A I K NPV+ A+K+ +I
Sbjct: 191 KAEAAAKIRKENPVVVAEKIQRI 213
>Z0D2_MOUSE (O88878) Zinc finger A20 domain containing protein 2
(Zinc finger protein 216)
Length = 213
Score = 120 bits (301), Expect = 2e-27
Identities = 67/203 (33%), Positives = 92/203 (45%), Gaps = 45/203 (22%)
Query: 15 PILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQ------------------DKLAATSVE 56
P+LC CGF+G T MCS CYK+ L +Q+ D + +
Sbjct: 11 PMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRAD 70
Query: 57 NIVNSCSNGNGKQAITADAVNVRVEPVEVKAVTAQISAD--------------------- 95
+N+C G + + V V PV + IS +
Sbjct: 71 AGLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPS 130
Query: 96 ------SSSGESLEVKAKTGPSRCGTCRKRVGLTGFSCKCGNVFCAMHRYSDKHDCPFDY 149
S S E K +RC CRK+VGLTGF C+CGN+FC +HRYSDKH+CP+DY
Sbjct: 131 VSQPSSSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRYSDKHNCPYDY 190
Query: 150 RAVGQEAIAKANPVIKADKLDKI 172
+A I K NPV+ A+K+ +I
Sbjct: 191 KAEAAAKIRKENPVVVAEKIQRI 213
>RABX_MOUSE (Q9JM13) Rab5 GDP/GTP exchange factor (Rabex-5)
Length = 491
Score = 42.4 bits (98), Expect = 5e-04
Identities = 27/119 (22%), Positives = 46/119 (37%), Gaps = 12/119 (10%)
Query: 5 DETGCQAPERPILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQDKL---------AATSV 55
+ G + +LC CG++G A CSKC+++ K Q ++
Sbjct: 6 ERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREE 65
Query: 56 ENIVNSCSNGNGKQAITADAVNVRVEPVEVKAVTAQ---ISADSSSGESLEVKAKTGPS 111
E S + G Q++T + + + VT SA S +G E++ PS
Sbjct: 66 EEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKKEIQEAKAPS 124
>RABX_BOVIN (O18973) Rab5 GDP/GTP exchange factor (Rabex-5)
Length = 492
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/120 (22%), Positives = 46/120 (37%), Gaps = 13/120 (10%)
Query: 5 DETGCQAPERPILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQDKL---------AATSV 55
+ G + +LC CG++G A CSKC+++ K Q ++
Sbjct: 6 ERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREE 65
Query: 56 ENIVNSCSNGNGKQAITADAVNVRVEPVEVKAVTAQ---ISADSSSG-ESLEVKAKTGPS 111
E S + G Q++T + + + VT SA S G + E++ PS
Sbjct: 66 EEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGAKKAEIQEAKAPS 125
>RABX_HUMAN (Q9UJ41) Rab5 GDP/GTP exchange factor (Rabex-5)
Length = 708
Score = 37.0 bits (84), Expect = 0.023
Identities = 13/46 (28%), Positives = 23/46 (49%)
Query: 5 DETGCQAPERPILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQDKL 50
+ G + +LC CG++G A CSKC+++ K Q ++
Sbjct: 144 ERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQI 189
>CEZ2_MOUSE (Q8R554) Zinc finger A20 domain containing protein ? (EC
3.-.-.-) (Zinc finger protein Cezanne 2)
Length = 926
Score = 35.8 bits (81), Expect = 0.050
Identities = 13/31 (41%), Positives = 21/31 (66%)
Query: 21 NCGFFGRAATMNMCSKCYKDMLLKQEQDKLA 51
NC F+GRA T + CS CY++ L ++ + + A
Sbjct: 894 NCAFYGRAETEHFCSYCYREELRRRREARAA 924
>CEZ1_HUMAN (Q6GQQ9) Zinc finger A20 domain containing protein 1 (EC
3.-.-.-) (Cellular zinc finger anti-NF-kappa B protein)
(Zinc finger protein Cezanne)
Length = 843
Score = 35.4 bits (80), Expect = 0.066
Identities = 15/43 (34%), Positives = 24/43 (54%), Gaps = 8/43 (18%)
Query: 6 ETGCQAPERPILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQD 48
+T C+ P NC F+G T N CS CY++ L ++E++
Sbjct: 799 QTKCKQP--------NCSFYGHPETNNFCSCCYREELRRRERE 833
>CEZ2_HUMAN (Q8TE49) Zinc finger A20 domain containing protein ? (EC
3.-.-.-) (Zinc finger protein Cezanne 2)
Length = 926
Score = 34.3 bits (77), Expect = 0.15
Identities = 12/27 (44%), Positives = 19/27 (69%)
Query: 21 NCGFFGRAATMNMCSKCYKDMLLKQEQ 47
NC F+GRA T + CS CY++ L ++ +
Sbjct: 894 NCAFYGRAETEHYCSYCYREELRRRRE 920
>KDGD_MESAU (Q64398) Diacylglycerol kinase, delta (EC 2.7.1.107)
(Diglyceride kinase) (DGK-delta) (DAG kinase delta) (130
kDa diacylglycerol kinase) (Diacylglycerol kinase, eta)
Length = 1154
Score = 33.5 bits (75), Expect = 0.25
Identities = 29/73 (39%), Positives = 37/73 (49%), Gaps = 9/73 (12%)
Query: 39 KDMLLKQE--QDKLAATSV--ENIVNSCSNGNGK-----QAITADAVNVRVEPVEVKAVT 89
KD + K E QDK +V E + N CS N K QA+ ADA RV P A+
Sbjct: 514 KDFVAKVEKAQDKTLENTVVAEAVANKCSVLNEKLEQLLQALHADAQASRVPPGVGPAIP 573
Query: 90 AQISADSSSGESL 102
+ + +SSS ESL
Sbjct: 574 EEDAVESSSEESL 586
>LEFB_NPVLD (Q9YMS9) Late expression factor 11
Length = 187
Score = 30.8 bits (68), Expect = 1.6
Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 62 CSNGNGKQAITADAVNVRVEPVEVKAVTAQISADSSSGESLEVKAKTGPSRC---GTCRK 118
C N + A+T +A+N R +VK V A + DS S +S ++ + CR+
Sbjct: 26 CLNRSEVYALTREAINKRKHLGDVKGVCAHLFDDSFSAQSDYIRENLATAFIVVGDNCRE 85
Query: 119 RVGLTGFSCKCGNVFCAMHR--YSDKH 143
R L + + VF R Y + H
Sbjct: 86 RKHLGQHAARFDRVFSLKRRTLYDEYH 112
>VP10_WTV (P13093) Nonstructural protein Pns10
Length = 345
Score = 30.4 bits (67), Expect = 2.1
Identities = 19/56 (33%), Positives = 28/56 (49%), Gaps = 2/56 (3%)
Query: 61 SCSNGNGKQAITADAVNVRVEPVEVKAVTAQISADSSS-GESLEVKAKTGPSRCGT 115
SCS+GN Q++ D + P EV+ T I+ S S +L+ T PS C +
Sbjct: 69 SCSDGNILQSVENDKKDTEGRPSEVRTSTQNIATSSRSVNSNLQCNTST-PSPCNS 123
>PYR1_DICDI (P20054) Protein PYR1-3 [Includes: Glutamine-dependent
carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC
3.5.2.3)]
Length = 2185
Score = 30.0 bits (66), Expect = 2.8
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 6/86 (6%)
Query: 74 DAVNVRVEPVEVKAVTAQISADSSSGESLEVKAKTGPSRCGTCRKRVGLTGFSC--KCGN 131
D + E + ++ + A++S E E KA + G RK + C K
Sbjct: 114 DESKLEFEDINLRNLVAEVSTK----EIKEYKAAENNKKTGEKRKNKKVIVLDCGIKNNQ 169
Query: 132 VFCAMHRYSDKHDCPFDYRAVGQEAI 157
+ C ++R D P+DY V E+I
Sbjct: 170 IRCLLNRGVDLKVVPWDYDVVANESI 195
>ITB1_BOVIN (P53712) Integrin beta-1 (Fibronectin receptor beta
subunit) (CD29) (Integrin VLA-4 beta subunit) (Fragment)
Length = 773
Score = 29.3 bits (64), Expect = 4.7
Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 29/119 (24%)
Query: 19 VNNCGFFGRAATMNMCSKCYKDMLLKQEQDKLAATSVENIVNSCSNGNGKQAITADAVNV 78
VN G GR KC + + Q +++ T+ N C N N + +
Sbjct: 382 VNGTGENGR--------KCSNISIGDEVQFEISITA-----NKCPNKNSE--------TI 420
Query: 79 RVEPV----EVKAVTAQISADSSSGESLEVKAK----TGPSRCGTCRKRVGLTGFSCKC 129
+++P+ EV+ + I GE + K G CG CR G G C+C
Sbjct: 421 KIKPLGFTEEVEIILQFICECECQGEGIPGSPKCHDGNGTFECGACRCNEGRVGRHCEC 479
>Z295_HUMAN (Q9ULJ3) Zinc finger protein 295 (Zinc finger and BTB
domain containing protein 21)
Length = 1066
Score = 28.9 bits (63), Expect = 6.1
Identities = 30/131 (22%), Positives = 53/131 (39%), Gaps = 29/131 (22%)
Query: 27 RAATMNMCSKCYKDMLLKQ---------EQDKLAATSVENIVNSCSNGNGKQAITADAVN 77
R +++CS LLK+ +++ L + + ++ S +G+G Q+I
Sbjct: 276 RPPVLSVCSSSETPYLLKETNKGNGQGEDRNLLYYSKLGLVIPSSGSGSGNQSID----- 330
Query: 78 VRVEPVEVKAVTAQISADSSS---GESLEVKAKTGPSRCGTCRKRVGLTGFSCKCGNVFC 134
R P+ + +S DS S+++K+ G S S GNV C
Sbjct: 331 -RSGPLVKSLLRRSLSMDSQVPVYSPSIDLKSSQGSSSVS-----------SDAPGNVLC 378
Query: 135 AMHRYSDKHDC 145
A+ + S DC
Sbjct: 379 ALSQKSSLKDC 389
>MTA_CARCW (Q8AWG2) Metallothionein A (MT-A)
Length = 60
Score = 28.9 bits (63), Expect = 6.1
Identities = 17/56 (30%), Positives = 20/56 (35%), Gaps = 10/56 (17%)
Query: 106 AKTGPSRCGTCRKRVGLTGFSCKCGNVFCAMHRYSDKHDCPFDYRAVGQEAIAKAN 161
AKTGP CG +CKC N C + S CP + K N
Sbjct: 7 AKTGPCNCGA----------TCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGN 52
>ITBX_DROME (P11584) Integrin beta-PS precursor (Position-specific
antigen, beta chain) (Myospheroid protein) (Olfactory C
protein)
Length = 846
Score = 28.9 bits (63), Expect = 6.1
Identities = 29/117 (24%), Positives = 45/117 (37%), Gaps = 12/117 (10%)
Query: 17 LCVNNCGFFGRAATMNMCSKCYKDMLLKQEQDKLAATSVENIVNSCSNGNGKQAITADAV 76
+C + +FG N C D+ K D + + CS G G A
Sbjct: 532 ICNCDDSYFG-----NKCECSATDLTSKFANDT-SCRADSTSTTDCS-GRGHCVCGACEC 584
Query: 77 NVRVEPVEVKAVTAQISADSSSGESLEVKAKTGPSR----CGTCRKRVGLTGFSCKC 129
+ R P+E+ + D+ S E + +GP CG C+ + G TG +C C
Sbjct: 585 HKRPNPIEIIS-GKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGC 640
>ARC2_ENTFA (P59625) Carbamate kinase 2 (EC 2.7.2.2)
Length = 312
Score = 28.9 bits (63), Expect = 6.1
Identities = 15/57 (26%), Positives = 28/57 (48%)
Query: 46 EQDKLAATSVENIVNSCSNGNGKQAITADAVNVRVEPVEVKAVTAQISADSSSGESL 102
E++ + A +++ CS G G + D V VE V K +A++ A++ + L
Sbjct: 171 EKEAVRALVEADVLTICSGGGGIPVVAEDGQYVGVEAVNDKDFSARVLAENVDADRL 227
>RPOA_ADICA (Q85FJ1) DNA-directed RNA polymerase alpha chain (EC
2.7.7.6) (PEP) (Plastid-encoded RNA polymerase alpha
subunit) (RNA polymerase alpha subunit)
Length = 345
Score = 28.5 bits (62), Expect = 8.0
Identities = 23/96 (23%), Positives = 41/96 (41%), Gaps = 2/96 (2%)
Query: 16 ILCVNNCGFFGRAATMNMCSKCYKDMLLKQEQDKLAATSVENIVNSCSNGNGKQAITA-- 73
I C CG +T+ + D L+ ++ L S E+I + S+ G + +TA
Sbjct: 62 ITCARFCGVVHEYSTITGLQETIHDALVNPKEIVLRGDSKEDIQEAFSSVTGPKEVTAGD 121
Query: 74 DAVNVRVEPVEVKAVTAQISADSSSGESLEVKAKTG 109
++ VE ++ A I+ S LE++ G
Sbjct: 122 PSLPPGVEAIDNSQYIATITQPISLTIELEIEKDCG 157
>RNP_RAT (P00684) Ribonuclease pancreatic precursor (EC 3.1.27.5)
(RNase 1) (RNase A) (RL1)
Length = 152
Score = 28.5 bits (62), Expect = 8.0
Identities = 15/43 (34%), Positives = 23/43 (52%), Gaps = 2/43 (4%)
Query: 93 SADSSSGESLEVK--AKTGPSRCGTCRKRVGLTGFSCKCGNVF 133
SAD + ++ + +K+ P+ C KR G+T SCK N F
Sbjct: 32 SADKFKRQHMDTEGPSKSSPTYCNQMMKRQGMTKGSCKPVNTF 74
>MT_ICTPU (O93571) Metallothionein (MT)
Length = 60
Score = 28.5 bits (62), Expect = 8.0
Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 10/41 (24%)
Query: 106 AKTGPSRCGTCRKRVGLTGFSCKCGNVFCAMHRYSDKHDCP 146
+KTG CGT SCKC N CA + S CP
Sbjct: 7 SKTGTCNCGT----------SCKCSNCQCACCKKSCCSCCP 37
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,269,674
Number of Sequences: 164201
Number of extensions: 686557
Number of successful extensions: 2020
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2005
Number of HSP's gapped (non-prelim): 26
length of query: 172
length of database: 59,974,054
effective HSP length: 102
effective length of query: 70
effective length of database: 43,225,552
effective search space: 3025788640
effective search space used: 3025788640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Lotus: description of TM0318.6