BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0299.13
(259 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SFR1_ARATH (O22315) Pre-mRNA splicing factor SF2 (SR1 protein) 332 4e-91
SFR1_HUMAN (Q07955) Splicing factor, arginine/serine-rich 1 (pre... 226 6e-59
SFR9_HUMAN (Q13242) Splicing factor, arginine/serine-rich 9 (Pre... 182 9e-46
SFR4_MOUSE (Q8VE97) Splicing factor, arginine/serine-rich 4 151 1e-36
SFR4_HUMAN (Q08170) Splicing factor, arginine/serine-rich 4 (Pre... 151 1e-36
SFR6_HUMAN (Q13247) Splicing factor, arginine/serine-rich 6 (Pre... 148 1e-35
SFR5_HUMAN (Q13243) Splicing factor, arginine/serine-rich 5 (Pre... 144 2e-34
SFR5_RAT (Q09167) Splicing factor, arginine/serine-rich 5 (Pre-m... 141 2e-33
SR55_DROME (P26686) Serine-arginine protein 55 (SRP55) (Enhancer... 140 3e-33
SFR5_MOUSE (O35326) Splicing factor, arginine/serine-rich 5 (Pre... 133 4e-31
SRP2_SCHPO (P78814) Pre-mRNA splicing factor srp2 97 5e-20
SFR7_HUMAN (Q16629) Splicing factor, arginine/serine-rich 7 (Spl... 83 8e-16
RS40_ARATH (P92965) Arginine/serine-rich splicing factor RSP40 72 1e-12
RBP1_DROME (Q02427) RNA-binding protein 1 72 1e-12
SFR3_MOUSE (P84104) Splicing factor, arginine/serine-rich 3 (Pre... 71 2e-12
SFR3_HUMAN (P84103) Splicing factor, arginine/serine-rich 3 (Pre... 71 2e-12
RS41_ARATH (P92966) Arginine/serine-rich splicing factor RSP41 70 7e-12
RS31_ARATH (P92964) Arginine/serine-rich splicing factor RSP31 69 1e-11
FUSI_MOUSE (Q9R0U0) FUS interacting serine-arginine rich protein... 67 3e-11
FUSI_HUMAN (O75494) FUS interacting serine-arginine rich protein... 67 3e-11
>SFR1_ARATH (O22315) Pre-mRNA splicing factor SF2 (SR1 protein)
Length = 303
Score = 332 bits (852), Expect = 4e-91
Identities = 179/250 (71%), Positives = 199/250 (79%), Gaps = 18/250 (7%)
Query: 1 MSSRSSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAED 60
MSSRSSRT+YVGNLPGDIR REVED+F K+GP+V IDLK+PPRPPGYAFV+F+DARDAED
Sbjct: 1 MSSRSSRTVYVGNLPGDIREREVEDLFSKYGPVVQIDLKVPPRPPGYAFVEFDDARDAED 60
Query: 61 AIYYRDGYDFDGFRLRVELAHGGRGSSSSVDRYSSYSGG----------SSSRGASRRSD 110
AI+ RDGYDFDG RLRVELAHGGR SS D S++GG SRG SRRS+
Sbjct: 61 AIHGRDGYDFDGHRLRVELAHGGRRSSD--DTRGSFNGGGRGGGRGRGDGGSRGPSRRSE 118
Query: 111 YRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDD 170
+RVLVTGLP SASWQDLKDHMRK GDVCFSQV+R+ G TG+VDYT Y+DMKYAL+KLDD
Sbjct: 119 FRVLVTGLPSSASWQDLKDHMRKGGDVCFSQVYRDARGTTGVVDYTCYEDMKYALKKLDD 178
Query: 171 SEFRNAFSRAYIRVREYD-RDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSIS 229
+EFRNAFS Y+RVREYD R SRSPSR RSYS+S SRS S SRSRSRS RS S
Sbjct: 179 TEFRNAFSNGYVRVREYDSRKDSRSPSRG--RSYSKSRSRSRGRSVSRSRSRS---RSRS 233
Query: 230 LSPTAKRSRR 239
SP AK SRR
Sbjct: 234 RSPKAKSSRR 243
>SFR1_HUMAN (Q07955) Splicing factor, arginine/serine-rich 1
(pre-mRNA splicing factor SF2, P33 subunit) (Alternative
splicing factor ASF-1) (OK/SW-cl.3)
Length = 247
Score = 226 bits (575), Expect = 6e-59
Identities = 132/239 (55%), Positives = 162/239 (67%), Gaps = 20/239 (8%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
IYVGNLP DIR +++ED+FYK+G I DIDLK P +AFV+FED RDAEDA+Y RDGY
Sbjct: 17 IYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGY 76
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRG----ASRRSDYRVLVTGLPPSASW 124
D+DG+RLRVE GRG+ GG + RG SRRS+ RV+V+GLPPS SW
Sbjct: 77 DYDGYRLRVEFPRSGRGTGRG---GGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSW 133
Query: 125 QDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFR-NAFSRAYIR 183
QDLKDHMR+AGDVC++ V+R+ TG+V++ +DM YA+RKLD+++FR + AYIR
Sbjct: 134 QDLKDHMREAGDVCYADVYRDG---TGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIR 190
Query: 184 VREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGR----SISLSPTAKRSR 238
V+ D RSPS RS SRS SRS SRS SRSRSYS R S SP RSR
Sbjct: 191 VKV---DGPRSPSYGRSRSRSRSRSRS--RSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 244
Score = 34.3 bits (77), Expect = 0.31
Identities = 18/52 (34%), Positives = 26/52 (49%)
Query: 97 SGGSSSRGASRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGG 148
SGG RG + +D R+ V LPP +D++D K G + + RGG
Sbjct: 1 SGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGG 52
>SFR9_HUMAN (Q13242) Splicing factor, arginine/serine-rich 9
(Pre-mRNA splicing factor SRp30C)
Length = 221
Score = 182 bits (461), Expect = 9e-46
Identities = 108/215 (50%), Positives = 139/215 (64%), Gaps = 29/215 (13%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
IYVGNLP D+R +++ED+FYK+G I +I+LK +AFV+FED RDAEDAIY R+GY
Sbjct: 16 IYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGY 75
Query: 69 DFDGFRLRVEL--AHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQD 126
D+ RLRVE +GGRG + G + +RRSD+RVLV+GLPPS SWQD
Sbjct: 76 DYGQCRLRVEFPRTYGGRGG---------WPRGGRNGPPTRRSDFRVLVSGLPPSGSWQD 126
Query: 127 LKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFR-NAFSRAYIRVR 185
LKDHMR+AGDVC++ V ++ GM V+Y +DM+YALRKLDD++FR + +YIRV
Sbjct: 127 LKDHMREAGDVCYADVQKDGVGM---VEYLRKEDMEYALRKLDDTKFRSHEGETSYIRV- 182
Query: 186 EYDRDYSRSPSRDSRRSYSRSIS-----RSPYLSR 215
P R + YSRS S SPY SR
Sbjct: 183 --------YPERSTSYGYSRSRSGSRGRDSPYQSR 209
>SFR4_MOUSE (Q8VE97) Splicing factor, arginine/serine-rich 4
Length = 489
Score = 151 bits (382), Expect = 1e-36
Identities = 104/253 (41%), Positives = 139/253 (54%), Gaps = 24/253 (9%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+Y+G L R R+VE F +G I+++DLK GY FV+F+D RDA+DA+Y +G
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK-----NGYGFVEFDDLRDADDAVYELNGK 58
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSR---GASRRSDYRVLVTGLPPSASWQ 125
D G R+ VE A G R S S Y S R G R++YR++V L SWQ
Sbjct: 59 DLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQ 118
Query: 126 DLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFR----------- 174
DLKD+MR+AG+V ++ + R G++++ +Y DMK AL KLD +E
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKN-EGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKP 177
Query: 175 -NAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS-GRSISLSP 232
+ R+Y R R + R SRS SR SR+S SRS S S+SRSRSRS S RS S S
Sbjct: 178 GSRRRRSYSRSRSHSR--SRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSR 235
Query: 233 TAKRSRRLLSLSR 245
+ RSR SR
Sbjct: 236 SQSRSRSKKEKSR 248
Score = 38.9 bits (89), Expect = 0.013
Identities = 69/277 (24%), Positives = 107/277 (37%), Gaps = 37/277 (13%)
Query: 3 SRSSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAI 62
+R+ + V NL ++++D + G + D + G ++F D + A+
Sbjct: 100 TRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGV--IEFVSYSDMKRAL 157
Query: 63 YYRDGYDFDGFRLR-VELAHGGR-----------GSSSSVDRYS----SYSGGSSSRGAS 106
DG + +G ++R VE G R S S R+S S SG S S +
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK 217
Query: 107 RRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALR 166
RS R S S + +K S+ + R D + +A
Sbjct: 218 SRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRS-PDKSRSKSKDHAED 276
Query: 167 KLDDSEF-----------RNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSR 215
KL +++ ++ SR+ + R + + RS SR + SRS +S SR
Sbjct: 277 KLQNNDSAGKAKSHSPSRHDSKSRSRSQERRAEEERRRSVSRARSQEKSRSQEKSLLKSR 336
Query: 216 SRSRSRSYS-------GRSISLSPTAKRSRRLLSLSR 245
SRSRSRS S GR S + RSR SR
Sbjct: 337 SRSRSRSRSRSKDKRKGRKRSRDESRSRSRSKSERSR 373
Score = 37.0 bits (84), Expect = 0.048
Identities = 50/180 (27%), Positives = 67/180 (36%), Gaps = 23/180 (12%)
Query: 53 EDARDAEDAIYYRDGYDFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYR 112
E +R E ++ R R + GR S R S S SR S + D +
Sbjct: 323 EKSRSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSRSKSERSRKHSSKRDSK 382
Query: 113 VLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSE 172
V + S+ + DH R V +ER ++ + + R +SE
Sbjct: 383 V--SSSSSSSKKKKDTDHSRSPS----RSVSKER-------EHAKAESGQRGSRAEGESE 429
Query: 173 FRNAFSRAYIR----------VREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRS 222
N RA R R S S +R +S SRS SRSP SRSRS SRS
Sbjct: 430 APNPEPRARSRSTSKSKPNVPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS 489
Score = 33.1 bits (74), Expect = 0.69
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 170 DSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSP------YLSRSRSRSRSY 223
+ E R + SRA R +E R +S + RS SRS SRS SR SRSRS
Sbjct: 309 EEERRRSVSRA--RSQEKSRSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSR 366
Query: 224 SGRSISLSPTAKRSRRLLSLS 244
S S ++KR ++ S S
Sbjct: 367 SKSERSRKHSSKRDSKVSSSS 387
Score = 30.4 bits (67), Expect = 4.5
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
Query: 178 SRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRS 237
SR+ R R D+ R SRD RS SRS S RSR S + S S ++K+
Sbjct: 339 SRSRSRSRSKDKRKGRKRSRDESRSRSRSKS-----ERSRKHSSKRDSKVSSSSSSSKKK 393
Query: 238 R 238
+
Sbjct: 394 K 394
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/83 (25%), Positives = 40/83 (47%), Gaps = 2/83 (2%)
Query: 159 DDMKYALRKLDDSEFRNAFSRAYIRVREYDRDYSRSPSRDSR--RSYSRSISRSPYLSRS 216
++ + ++ + E + ++ ++ R R SRS S+D R R SR SRS S+S
Sbjct: 310 EERRRSVSRARSQEKSRSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSRSKS 369
Query: 217 RSRSRSYSGRSISLSPTAKRSRR 239
+ S R +S ++ S++
Sbjct: 370 ERSRKHSSKRDSKVSSSSSSSKK 392
>SFR4_HUMAN (Q08170) Splicing factor, arginine/serine-rich 4
(Pre-mRNA splicing factor SRP75) (SRP001LB)
Length = 494
Score = 151 bits (382), Expect = 1e-36
Identities = 104/253 (41%), Positives = 139/253 (54%), Gaps = 24/253 (9%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+Y+G L R R+VE F +G I+++DLK GY FV+F+D RDA+DA+Y +G
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK-----NGYGFVEFDDLRDADDAVYELNGK 58
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSR---GASRRSDYRVLVTGLPPSASWQ 125
D G R+ VE A G R S S Y S R G R++YR++V L SWQ
Sbjct: 59 DLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQ 118
Query: 126 DLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFR----------- 174
DLKD+MR+AG+V ++ + R G++++ +Y DMK AL KLD +E
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKN-EGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKP 177
Query: 175 -NAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS-GRSISLSP 232
+ R+Y R R + R SRS SR SR+S SRS S S+SRSRSRS S RS S S
Sbjct: 178 GSRRRRSYSRSRSHSR--SRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 233 TAKRSRRLLSLSR 245
+ RSR SR
Sbjct: 236 SQSRSRSKKEKSR 248
Score = 38.1 bits (87), Expect = 0.021
Identities = 66/259 (25%), Positives = 103/259 (39%), Gaps = 26/259 (10%)
Query: 3 SRSSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAI 62
+R+ + V NL ++++D + G + D + G ++F D + A+
Sbjct: 100 TRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGV--IEFVSYSDMKRAL 157
Query: 63 YYRDGYDFDGFRLR-VELAHGGR-----------GSSSSVDRYS----SYSGGSSSRGAS 106
DG + +G ++R VE G R S S R+S S SG S S +
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK 217
Query: 107 RRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFS-QVFRERGGMTGIVDYTNYDDMKYAL 165
RS R S S + +K S + R R G + D + +
Sbjct: 218 SRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI 277
Query: 166 RKLDDSEFRNAFSRAYIRVREYDRDYSRSPSR----DSRRSYSRSISRSPYLSRSRSRSR 221
+ D+ SR+ R + + SRS R + R S SR S+ L +SRSRSR
Sbjct: 278 QNNDN--VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 222 SYSG-RSISLSPTAKRSRR 239
S G RS S S + + +R
Sbjct: 336 SKGGSRSRSRSRSKSKDKR 354
Score = 37.7 bits (86), Expect = 0.028
Identities = 29/79 (36%), Positives = 39/79 (48%), Gaps = 3/79 (3%)
Query: 160 DMKYALRKLDDSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSR 219
+ ++A + E R A R S S S+ + S SRS S+S +RSRS+
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 220 SRSYSGRSISLSPTAKRSR 238
SRS RS S SP+ RSR
Sbjct: 474 SRS---RSASRSPSRSRSR 489
Score = 36.6 bits (83), Expect = 0.062
Identities = 22/48 (45%), Positives = 27/48 (55%)
Query: 175 NAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRS 222
N+ S+ + R S S +R +S SRS SRSP SRSRS SRS
Sbjct: 447 NSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 34.7 bits (78), Expect = 0.24
Identities = 24/58 (41%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 170 DSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRS 227
+ R + SR+ + R SRS S+D R+ RS SRSRSRSRS S RS
Sbjct: 324 EKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE----SRSRSRSRSKSERS 377
Score = 33.5 bits (75), Expect = 0.53
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 192 SRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS 224
SRS S RS S+S SRS S SRSRSRS+S
Sbjct: 460 SRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 32.0 bits (71), Expect = 1.5
Identities = 19/33 (57%), Positives = 23/33 (69%)
Query: 192 SRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS 224
SRS S+ + ++ SRS SRS SRS SRSRS S
Sbjct: 458 SRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Score = 30.0 bits (66), Expect = 5.8
Identities = 26/78 (33%), Positives = 36/78 (45%), Gaps = 8/78 (10%)
Query: 170 DSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSR--------SRSRSR 221
+ E R + SR + + + SRS S+ RS SRS S+S + SRSRSR
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369
Query: 222 SYSGRSISLSPTAKRSRR 239
S S S +KR +
Sbjct: 370 SRSKSERSRKRGSKRDSK 387
>SFR6_HUMAN (Q13247) Splicing factor, arginine/serine-rich 6
(Pre-mRNA splicing factor SRP55)
Length = 344
Score = 148 bits (374), Expect = 1e-35
Identities = 102/258 (39%), Positives = 144/258 (55%), Gaps = 33/258 (12%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+Y+G L ++R ++++ F +G ++++DLK GY FV+FED+RDA+DA+Y +G
Sbjct: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK-----NGYGFVEFEDSRDADDAVYELNGK 58
Query: 69 DFDGFRLRVELAHGGR--------GSSSSVDRYSSY-SGGSSSRGASRRSDYRVLVTGLP 119
+ G R+ VE A G R GS S YSS + G G R++YR++V L
Sbjct: 59 ELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLS 118
Query: 120 PSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEF------ 173
SWQDLKD MR+AG+V ++ +ER G++++ +Y DMK AL KLD +E
Sbjct: 119 SRCSWQDLKDFMRQAGEVTYADAHKERTN-EGVIEFRSYSDMKRALDKLDGTEINGRNIR 177
Query: 174 ------RNAFSRAY--IRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRS----RSRSR 221
R + R+Y R R R SRS SR S RS SRSIS+S SRS RSRSR
Sbjct: 178 LIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSR 237
Query: 222 SYSGRSISLSPTAKRSRR 239
S +S S S + +S R
Sbjct: 238 SKGRKSRSKSKSKPKSDR 255
Score = 32.3 bits (72), Expect = 1.2
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 26/248 (10%)
Query: 4 RSSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIY 63
R+ + V NL ++++D + G + D G ++F D + A+
Sbjct: 107 RTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGV--IEFRSYSDMKRALD 164
Query: 64 YRDGYDFDGFRLRV---------ELAHGGRGSSSSVDRYSSYSGGSSSRGASR-----RS 109
DG + +G +R+ ++ G S S R S SSR SR RS
Sbjct: 165 KLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRS 224
Query: 110 DYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLD 169
R G S S RK+ S+ +RG + + + K R
Sbjct: 225 RSRSRSKGRSRSRS------KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRS 278
Query: 170 DSEFRNAFSRAYIRVREYDRDYSRSPSR-DSRRSYSRSISRSPYLSRSRSRSRSYSGRSI 228
S N + I+ + R SRS S S +RS+S P + SRSRSRS S +S
Sbjct: 279 RSPKENG--KGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRS-KSR 335
Query: 229 SLSPTAKR 236
S S ++ R
Sbjct: 336 SRSRSSSR 343
>SFR5_HUMAN (Q13243) Splicing factor, arginine/serine-rich 5
(Pre-mRNA splicing factor SRP40) (Delayed-early protein
HRS)
Length = 272
Score = 144 bits (363), Expect = 2e-34
Identities = 103/256 (40%), Positives = 141/256 (54%), Gaps = 33/256 (12%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+++G L R ++VE F +G I DIDLK G+ FV+FED RDA+DA+Y DG
Sbjct: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK-----RGFGFVEFEDPRDADDAVYELDGK 60
Query: 69 DFDGFRLRVELA----HGGRGSSSSVDRYSSYSGGSSSRGASR-RSDYRVLVTGLPPSAS 123
+ R+ +E A GGRG DR+SS + R A R++ R++V L S
Sbjct: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 124 WQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFR--------- 174
WQDLKD MR+AG+V F+ R + G+V++ +Y D+K A+ KL E
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLN-EGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEG 179
Query: 175 -----NAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSIS 229
+ SR+ R R R SRS SR SR+SYSRS SR SRSRSRS+S RS+S
Sbjct: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSR-SRKSYSRSRSR----SRSRSRSKS---RSVS 231
Query: 230 LSPTAKRSRRLLSLSR 245
SP ++S++ S SR
Sbjct: 232 RSPVPEKSQKRGSSSR 247
>SFR5_RAT (Q09167) Splicing factor, arginine/serine-rich 5 (Pre-mRNA
splicing factor SRP40) (Insulin-induced growth response
protein CL-4) (Delayed-early protein HRS)
Length = 269
Score = 141 bits (355), Expect = 2e-33
Identities = 101/245 (41%), Positives = 136/245 (55%), Gaps = 14/245 (5%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+++G L R ++VE F +G I DIDLK G+ FV+FED RDA+DA+Y DG
Sbjct: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK-----RGFGFVEFEDPRDADDAVYELDGK 60
Query: 69 DFDGFRLRVELA----HGGRGSSSSVDRYSSYSGGSSSRGASR-RSDYRVLVTGLPPSAS 123
+ R+ +E A GGRG DR+SS + R A R++ R++V L S
Sbjct: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 124 WQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYI- 182
WQDLKD MR+AG+V F+ R + G+V++ +Y D+K A+ KL E +
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLN-EGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEG 179
Query: 183 RVREYDRDYSRSPSRDSRRSYSRSIS-RSPYLSRSRSRSRSYS-GRSISLSPTAKRSRRL 240
R R SRS +R S RS SRS S RS SRSRSRSRS S RS S SP ++S++
Sbjct: 180 SKRHRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKR 239
Query: 241 LSLSR 245
S SR
Sbjct: 240 GSSSR 244
>SR55_DROME (P26686) Serine-arginine protein 55 (SRP55) (Enhancer of
deformed) (52-kDa bracketing protein) (B52 protein)
Length = 375
Score = 140 bits (353), Expect = 3e-33
Identities = 103/279 (36%), Positives = 142/279 (49%), Gaps = 55/279 (19%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+YVG LP +R R++E F +G DI +K GY FV+FED RDA+DA+Y +G
Sbjct: 5 VYVGGLPYGVRERDLERFFKGYGRTRDILIK-----NGYGFVEFEDYRDADDAVYELNGK 59
Query: 69 DFDGFRLRVELAHG-GRGSSSSV--DRYSSYSGGS---------SSRGASR-----RSDY 111
+ G R+ VE A G RGS+ DRY GG +SR +SR R++Y
Sbjct: 60 ELLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEY 119
Query: 112 RVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDS 171
R++V L SWQDLKD+MR+AG+V ++ ++R G+V++ + DMK A+ KLDD+
Sbjct: 120 RLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRN-EGVVEFASLSDMKTAIEKLDDT 178
Query: 172 EF---------------------------RNAFSRAYIRVREYDRDYSRSPSRDSRRSYS 204
E R++ SR+ R R R + SR RS S
Sbjct: 179 ELNGRRIHLVEDRRGGASGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSTHSRSKSRSRS 238
Query: 205 -----RSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSR 238
RS S+SP SRSRSRS S R +S S + SR
Sbjct: 239 KSRGGRSKSKSPVKSRSRSRSASNKSRDVSKSKSKSHSR 277
Score = 45.4 bits (106), Expect = 1e-04
Identities = 62/230 (26%), Positives = 90/230 (38%), Gaps = 25/230 (10%)
Query: 4 RSSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIY 63
R+ + V NL + ++++D + G + D R G V+F D + AI
Sbjct: 116 RTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGV--VEFASLSDMKTAIE 173
Query: 64 YRDGYDFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSAS 123
D + +G R+ L RG +S GG S RG SR S R S S
Sbjct: 174 KLDDTELNG--RRIHLVEDRRGGASG-------GGGGSGRGRSRSSSSRSRSRSRRRSRS 224
Query: 124 WQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIR 183
+ + + RGG + + +K R S S++ +
Sbjct: 225 RRSTHSRSKSRSRS------KSRGGRS-----KSKSPVKSRSRSRSASNKSRDVSKS--K 271
Query: 184 VREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSISLSPT 233
+ + R SP R+ R S SRS S S SRSRSRS+S S S PT
Sbjct: 272 SKSHSRTAPVSPKRE-RDSRSRSRSVSKRESRSRSRSKSIHRDSRSRPPT 320
>SFR5_MOUSE (O35326) Splicing factor, arginine/serine-rich 5
(Pre-mRNA splicing factor SRP40) (Delayed-early protein
HRS)
Length = 270
Score = 133 bits (335), Expect = 4e-31
Identities = 99/246 (40%), Positives = 133/246 (53%), Gaps = 15/246 (6%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+++G L R ++VE F +G I DIDLK G+ FV+FED RDA+DA+Y DG
Sbjct: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK-----RGFGFVEFEDPRDADDAVYELDGK 60
Query: 69 DFDGFRLRVELA----HGGRGSSSSVDRYSSYSGGSSSRGASR-RSDYRVLVTGLPPSAS 123
+ R+ +E A GGRG DR + G+ R S ++ R++V L S
Sbjct: 61 ELCSERVTIEHARARSRGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLIVENLSSRVS 120
Query: 124 WQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIR 183
WQDLKD MR+AG+V F+ R + G+V++ +Y D+K A+ KL I
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLN-EGVVEFASYGDLKNAIEKLSWKRKLTGEKSKLIE 179
Query: 184 --VREYDRDYSRSPSRDSRRSYSRSIS-RSPYLSRSRSRSRSYS-GRSISLSPTAKRSRR 239
R R SRS +R S RS SRS S RS SRSRSRSRS S RS S SP ++S++
Sbjct: 180 GSKRHRSRSRSRSRTRSSLRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQK 239
Query: 240 LLSLSR 245
S SR
Sbjct: 240 RGSSSR 245
>SRP2_SCHPO (P78814) Pre-mRNA splicing factor srp2
Length = 365
Score = 96.7 bits (239), Expect = 5e-20
Identities = 76/245 (31%), Positives = 106/245 (43%), Gaps = 39/245 (15%)
Query: 5 SSRTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYY 64
S ++VG +P ++ D F +G I+D L G+ FV+ EDARDA D +
Sbjct: 2 SETRLFVGRIPPQATREDMMDFFKGYGQILDCKLM-----NGFGFVEVEDARDARDIVND 56
Query: 65 RDGYDFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASW 124
G +F G R+ VE A G R R + +S RR+ +R++V L SW
Sbjct: 57 FQGKEFMGSRIVVEPARGERRR-----RENFRESAASKYPRPRRTGFRLIVENLSEDVSW 111
Query: 125 QDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLD--------------- 169
QDLKD MRKAG+ F+ RE G G+V+++ +DM+ AL L+
Sbjct: 112 QDLKDVMRKAGEPTFTDAHRENPG-AGVVEFSTEEDMRNALTSLNGEVIKGQAVTLREDP 170
Query: 170 ----------DSEFRNAFSRAYIRVREYDR---DYSRSPSRDSRRSYSRSISRSPYLSRS 216
S FR+ A R R+ R DY R R R R R Y +
Sbjct: 171 DAANEPLPEVPSRFRSRSPPARRRYRDDYRRGGDYRRDAYRPGRDDERRYAPRGEYRRNN 230
Query: 217 RSRSR 221
R R
Sbjct: 231 RDEYR 235
>SFR7_HUMAN (Q16629) Splicing factor, arginine/serine-rich 7
(Splicing factor 9G8)
Length = 238
Score = 82.8 bits (203), Expect = 8e-16
Identities = 81/235 (34%), Positives = 101/235 (42%), Gaps = 53/235 (22%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+YVGNL E+E F +GP+ + I PPG+AFV+FED RDAEDA+ DG
Sbjct: 13 VYVGNLGTGAGKGELERAFSYYGPLRTV--WIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQDLK 128
G R+RVEL S G RRS + PP+ D
Sbjct: 71 VICGSRVRVEL----------------------STGMPRRSRF-----DRPPARRPFDPN 103
Query: 129 DHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIRVREYD 188
D + G E+G + YD +Y+ R+ S R S + R R Y
Sbjct: 104 DRCYECG---------EKG-------HYAYDCHRYSRRRRSRSRSR---SHSRSRGRRYS 144
Query: 189 RDYSRSPSRDSR-----RSYSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSR 238
R SRS R SR RS S S+ RS S RSRS S G SP+ RSR
Sbjct: 145 RSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSR 199
Score = 39.7 bits (91), Expect = 0.007
Identities = 33/73 (45%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
Query: 187 YDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSRRL------ 240
Y D R R RS SRS SRS SRSRSRS RS S SP RS L
Sbjct: 115 YAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSA 174
Query: 241 -LSLSRCGLLRGS 252
L SR G ++GS
Sbjct: 175 SLRRSRSGSIKGS 187
>RS40_ARATH (P92965) Arginine/serine-rich splicing factor RSP40
Length = 350
Score = 72.0 bits (175), Expect = 1e-12
Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 25/238 (10%)
Query: 7 RTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRD 66
+ ++ GN D R ++E +F K+G + +D+K G+AFV ED RDAEDAI D
Sbjct: 2 KPVFCGNFEYDAREGDLERLFRKYGKVERVDMKA-----GFAFVYMEDERDAEDAIRALD 56
Query: 67 GYDF--DGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGAS--RRSDYRVLVTGLPPSA 122
++F G RLRVE RG SGG S R +S R S ++ +
Sbjct: 57 RFEFGRKGRRLRVEWTKSERGGDKR-------SGGGSRRSSSSMRPSKTLFVINFDADNT 109
Query: 123 SWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYI 182
+DL+ H G + ++ R + Y +D AL ++S+ +
Sbjct: 110 RTRDLEKHFEPYGKIVNVRIRRN----FAFIQYEAQEDATRALDASNNSKLMDKVISVEY 165
Query: 183 RVREYD-RDYSRSPSRDSRRS-YSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSR 238
V++ D R SP R RS R S SPY R R GR S ++ R
Sbjct: 166 AVKDDDARGNGHSPERRRDRSPERRRRSPSPY---KRERGSPDYGRGASPVAAYRKER 220
>RBP1_DROME (Q02427) RNA-binding protein 1
Length = 144
Score = 72.0 bits (175), Expect = 1e-12
Identities = 46/105 (43%), Positives = 59/105 (55%), Gaps = 10/105 (9%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+YVGNL E+E F K+GP+ ++ + PPG+AFV+FED RDAEDA DG
Sbjct: 13 VYVGNLGSSASKHEIEGAFAKYGPLRNV--WVARNPPGFAFVEFEDRRDAEDATRALDGT 70
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRV 113
G R+RVE++ G S DR GGSS R S R YR+
Sbjct: 71 RCCGTRIRVEMSSG-----RSRDRRRG-EGGSSGRSGSGR--YRI 107
>SFR3_MOUSE (P84104) Splicing factor, arginine/serine-rich 3
(Pre-mRNA splicing factor SRP20) (X16 protein)
Length = 164
Score = 71.2 bits (173), Expect = 2e-12
Identities = 67/211 (31%), Positives = 85/211 (39%), Gaps = 59/211 (27%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+YVGNL + E+E F +GP+ + + PPG+AFV+FED RDA DA+ DG
Sbjct: 12 VYVGNLGNNGNKTELERAFGYYGPLRSV--WVARNPPGFAFVEFEDPRDAADAVRELDGR 69
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQDLK 128
G R+RVEL++G ++ S G S G R DYR PP
Sbjct: 70 TLCGCRVRVELSNG--------EKRSRNRGPPPSWGRRPRDDYR---RRSPPP------- 111
Query: 129 DHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIRVREYD 188
R R S R +FSR+ R D
Sbjct: 112 ---------------RRR------------------------SPRRRSFSRSRSRSLSRD 132
Query: 189 RDYSRSPSRDSRRSYSRSISRSPYLSRSRSR 219
R RS SR+ SRS SRS SRS R
Sbjct: 133 RRRERSLSRERNHKPSRSFSRSRSRSRSNER 163
Score = 36.2 bits (82), Expect = 0.081
Identities = 46/154 (29%), Positives = 62/154 (39%), Gaps = 22/154 (14%)
Query: 82 GGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQ 141
G G+ + ++R Y G S +R PP ++ + +D R A D
Sbjct: 18 GNNGNKTELERAFGYYGPLRSVWVARN----------PPGFAFVEFEDP-RDAADAVREL 66
Query: 142 VFRERGGMTGIVDYTNYDDMK--------YALRKLDDSEFRNAFSRAYI-RVREYDRDYS 192
R G V+ +N + + R DD R+ R R R + R S
Sbjct: 67 DGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRS 126
Query: 193 RSPSRDSRR--SYSRSISRSPYLSRSRSRSRSYS 224
RS SRD RR S SR + P S SRSRSRS S
Sbjct: 127 RSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRS 160
>SFR3_HUMAN (P84103) Splicing factor, arginine/serine-rich 3
(Pre-mRNA splicing factor SRP20)
Length = 164
Score = 71.2 bits (173), Expect = 2e-12
Identities = 67/211 (31%), Positives = 85/211 (39%), Gaps = 59/211 (27%)
Query: 9 IYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRDGY 68
+YVGNL + E+E F +GP+ + + PPG+AFV+FED RDA DA+ DG
Sbjct: 12 VYVGNLGNNGNKTELERAFGYYGPLRSV--WVARNPPGFAFVEFEDPRDAADAVRELDGR 69
Query: 69 DFDGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQDLK 128
G R+RVEL++G ++ S G S G R DYR PP
Sbjct: 70 TLCGCRVRVELSNG--------EKRSRNRGPPPSWGRRPRDDYR---RRSPPP------- 111
Query: 129 DHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIRVREYD 188
R R S R +FSR+ R D
Sbjct: 112 ---------------RRR------------------------SPRRRSFSRSRSRSLSRD 132
Query: 189 RDYSRSPSRDSRRSYSRSISRSPYLSRSRSR 219
R RS SR+ SRS SRS SRS R
Sbjct: 133 RRRERSLSRERNHKPSRSFSRSRSRSRSNER 163
Score = 36.2 bits (82), Expect = 0.081
Identities = 46/154 (29%), Positives = 62/154 (39%), Gaps = 22/154 (14%)
Query: 82 GGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQ 141
G G+ + ++R Y G S +R PP ++ + +D R A D
Sbjct: 18 GNNGNKTELERAFGYYGPLRSVWVARN----------PPGFAFVEFEDP-RDAADAVREL 66
Query: 142 VFRERGGMTGIVDYTNYDDMK--------YALRKLDDSEFRNAFSRAYI-RVREYDRDYS 192
R G V+ +N + + R DD R+ R R R + R S
Sbjct: 67 DGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRS 126
Query: 193 RSPSRDSRR--SYSRSISRSPYLSRSRSRSRSYS 224
RS SRD RR S SR + P S SRSRSRS S
Sbjct: 127 RSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRS 160
>RS41_ARATH (P92966) Arginine/serine-rich splicing factor RSP41
Length = 356
Score = 69.7 bits (169), Expect = 7e-12
Identities = 69/237 (29%), Positives = 100/237 (42%), Gaps = 24/237 (10%)
Query: 7 RTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRD 66
+ ++ GN D R ++E +F K+G + +D+K G+AFV ED RDAEDAI D
Sbjct: 2 KPVFCGNFEYDARESDLERLFRKYGKVERVDMKA-----GFAFVYMEDERDAEDAIRALD 56
Query: 67 GYDF--DGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGL-PPSAS 123
+++ G RLRVE RG + SGGS + R + V +
Sbjct: 57 RFEYGRTGRRLRVEWTKNDRGGAGR-------SGGSRRSSSGLRPSKTLFVINFDAQNTR 109
Query: 124 WQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIR 183
+DL+ H G + ++ R + Y +D AL + S+ +
Sbjct: 110 TRDLERHFEPYGKIVNVRIRRN----FAFIQYEAQEDATRALDATNSSKLMDKVISVEYA 165
Query: 184 VREYD-RDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSRR 239
V++ D R SP R RS R RSP R S Y GR SP A + R
Sbjct: 166 VKDDDSRGNGYSPERRRDRSPDRR-RRSPSPYRRERGSPDY-GR--GASPVAHKRER 218
>RS31_ARATH (P92964) Arginine/serine-rich splicing factor RSP31
Length = 264
Score = 68.6 bits (166), Expect = 1e-11
Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 7 RTIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIPPRPPGYAFVQFEDARDAEDAIYYRD 66
R ++VGN + R ++E +F K+G + +D+K GYAFV FED RDAEDAI D
Sbjct: 2 RPVFVGNFEYETRQSDLERLFDKYGRVDRVDMK-----SGYAFVYFEDERDAEDAIRKLD 56
Query: 67 GYDF--DGFRLRVELAHGGRGSSSSVDRYSSYSGGSSSRGASRRSDYRVLVTGLPPSASW 124
+ F + RL VE A G RG G + ++ + + V P +
Sbjct: 57 NFPFGYEKRRLSVEWAKGERGRPR----------GDAKAPSNLKPTKTLFVINFDPIRTK 106
Query: 125 Q-DLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYALRKLDDSEFRNAFSRAYIR 183
+ D++ H G V ++ R V + +D AL S+ +
Sbjct: 107 EHDIEKHFEPYGKVTNVRIRRN----FSFVQFETQEDATKALEATQRSKILDRVVSVEYA 162
Query: 184 VREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYSGRSISLSPTAKRSR 238
+++ D R+ R RRS S R P R R G+ SP R+R
Sbjct: 163 LKDDDERDDRNGGRSPRRSLSPVYRRRPSPDYGR---RPSPGQGRRPSPDYGRAR 214
>FUSI_MOUSE (Q9R0U0) FUS interacting serine-arginine rich protein 1
(TLS-associated protein with Ser-Arg repeats)
(TLS-associated protein with SR repeats) (TASR)
(TLS-associated serine-arginine protein) (TLS-associated
SR protein) (Neural specific SR prot
Length = 262
Score = 67.4 bits (163), Expect = 3e-11
Identities = 68/253 (26%), Positives = 111/253 (42%), Gaps = 27/253 (10%)
Query: 8 TIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIP---PRPPGYAFVQFEDARDAEDAIYY 64
+++V N+ D R ++ F ++GPIVD+ + + RP G+A+VQFED RDAEDA++
Sbjct: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
Query: 65 RDGYDFDGFRLRVELAHGGRG--------------SSSSVDRYSSYSGGSS-----SRGA 105
D G ++ ++ A G R SSS D Y Y S R
Sbjct: 71 LDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSR 130
Query: 106 SRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYAL 165
SR DY + P ++ R D + F+ R + K
Sbjct: 131 SRSFDYNYRRSYSPRNSRPTGRPRRSRSHSD---NDRFKHRNRSFSRSKSNSRSRSKSQP 187
Query: 166 RKLDDSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS- 224
+K ++ R+ S ++ + R + S++ + R S + P S+S+SRS+S S
Sbjct: 188 KKEMKAKSRSR-SASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSR 246
Query: 225 GRSISLSPTAKRS 237
+S S S T+ +S
Sbjct: 247 SKSRSRSWTSPKS 259
>FUSI_HUMAN (O75494) FUS interacting serine-arginine rich protein 1
(TLS-associated protein with Ser-Arg repeats)
(TLS-associated protein with SR repeats) (TASR)
(TLS-associated serine-arginine protein) (TLS-associated
SR protein) (40 kDa SR-repressor pro
Length = 262
Score = 67.4 bits (163), Expect = 3e-11
Identities = 68/253 (26%), Positives = 111/253 (42%), Gaps = 27/253 (10%)
Query: 8 TIYVGNLPGDIRLREVEDIFYKFGPIVDIDLKIP---PRPPGYAFVQFEDARDAEDAIYY 64
+++V N+ D R ++ F ++GPIVD+ + + RP G+A+VQFED RDAEDA++
Sbjct: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
Query: 65 RDGYDFDGFRLRVELAHGGRG--------------SSSSVDRYSSYSGGSS-----SRGA 105
D G ++ ++ A G R SSS D Y Y S R
Sbjct: 71 LDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSR 130
Query: 106 SRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSQVFRERGGMTGIVDYTNYDDMKYAL 165
SR DY + P ++ R D + F+ R + K
Sbjct: 131 SRSFDYNYRRSYSPRNSRPTGRPRRSRSHSD---NDRFKHRNRSFSRSKSNSRSRSKSQP 187
Query: 166 RKLDDSEFRNAFSRAYIRVREYDRDYSRSPSRDSRRSYSRSISRSPYLSRSRSRSRSYS- 224
+K ++ R+ S ++ + R + S++ + R S + P S+S+SRS+S S
Sbjct: 188 KKEMKAKSRSR-SASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSR 246
Query: 225 GRSISLSPTAKRS 237
+S S S T+ +S
Sbjct: 247 SKSRSRSWTSPKS 259
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,480,731
Number of Sequences: 164201
Number of extensions: 1382165
Number of successful extensions: 7129
Number of sequences better than 10.0: 472
Number of HSP's better than 10.0 without gapping: 266
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 4406
Number of HSP's gapped (non-prelim): 1504
length of query: 259
length of database: 59,974,054
effective HSP length: 108
effective length of query: 151
effective length of database: 42,240,346
effective search space: 6378292246
effective search space used: 6378292246
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Lotus: description of TM0299.13