BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0283.13
(488 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose... 280 6e-75
GTR8_MOUSE (Q9JIF3) Solute carrier family 2, facilitated glucose... 279 1e-74
GTR8_RAT (Q9JJZ1) Solute carrier family 2, facilitated glucose t... 278 3e-74
GTR6_HUMAN (Q9UGQ3) Solute carrier family 2, facilitated glucose... 247 4e-65
GTR3_RAT (Q07647) Solute carrier family 2, facilitated glucose t... 229 9e-60
GTR3_MOUSE (P32037) Solute carrier family 2, facilitated glucose... 229 2e-59
GTR3_CANFA (P47842) Solute carrier family 2, facilitated glucose... 225 2e-58
GTR3_SHEEP (P47843) Solute carrier family 2, facilitated glucose... 223 7e-58
GTR3_BOVIN (P58352) Solute carrier family 2, facilitated glucose... 221 3e-57
XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose transpor... 221 4e-57
GTR2_HUMAN (P11168) Solute carrier family 2, facilitated glucose... 220 7e-57
GTR3_CHICK (P28568) Solute carrier family 2, facilitated glucose... 219 1e-56
CSBC_BACSU (P46333) Probable metabolite transport protein csbC 218 4e-56
ITR1_YEAST (P30605) Myo-inositol transporter 1 216 1e-55
GTR4_MOUSE (P14142) Solute carrier family 2, facilitated glucose... 215 2e-55
GTR4_RAT (P19357) Solute carrier family 2, facilitated glucose t... 214 5e-55
GTR4_HUMAN (P14672) Solute carrier family 2, facilitated glucose... 213 7e-55
ITR2_YEAST (P30606) Myo-inositol transporter 2 212 2e-54
GALP_ECOLI (P37021) Galactose-proton symporter (Galactose transp... 211 3e-54
GTR3_HUMAN (P11169) Solute carrier family 2, facilitated glucose... 211 3e-54
>GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 477
Score = 280 bits (716), Expect = 6e-75
Identities = 168/458 (36%), Positives = 255/458 (54%), Gaps = 28/458 (6%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPT----QDAIVSDLKLSLSEFSLFGSLSNVGAMVGAI 104
V AALGP+ FGF GYSSP Q A +L + S FG++ +GA G +
Sbjct: 26 VFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGV 85
Query: 105 ASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYI 164
G + + GRK SL++ ++P + G+ I+ A+D L GRLL G G+ S V PVYI
Sbjct: 86 LGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYI 145
Query: 165 AEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVNWRVLAILGILPCTILIPGLFFIPES 224
+EIA +RG LGS QL V +GILLAYL G + WR LA+LG +P ++++ + F+PE+
Sbjct: 146 SEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPET 205
Query: 225 PRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQRKRYWFP 284
PR+L +E ++L+ L G E P G + A L++ + P
Sbjct: 206 PRFLLTQHRRQEAMAALRFLWG---------SEQGWEDPPIGAEQSFHLALLRQPGIYKP 256
Query: 285 LMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAATVGLGAIQVIATGISTWLVDKS 344
++G+ L+ QQLSG+N V+FY+ +IF A SS A+V +G IQV+ T ++ ++D++
Sbjct: 257 FIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRA 316
Query: 345 GRRLLLLLSSSIMTVSLVVVSIAFYL-EGTVSEDSHLYKI-------------LGIVSVV 390
GRRLLL+LS +M S F L +G SH+ L ++V
Sbjct: 317 GRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVG 376
Query: 391 GLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-ANLLLTWS 449
+ + + GF++G GPIPW++MSEI P+ +KG+A + NWL ++ +T ++L+
Sbjct: 377 SMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLR 436
Query: 450 SGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
G F + + F+V+FT VPETKG+TLE+I + F
Sbjct: 437 PYGAFWLASAFCIFSVLFTFSCVPETKGKTLEQITAHF 474
>GTR8_MOUSE (Q9JIF3) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 477
Score = 279 bits (713), Expect = 1e-74
Identities = 169/457 (36%), Positives = 258/457 (55%), Gaps = 26/457 (5%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPTQDAIVSD----LKLSLSEFSLFGSLSNVGAMVGAI 104
V AALGP+ FGF GYSSP ++ L+L + S FG++ +GA G I
Sbjct: 26 VFLASFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDNAASWFGAVVTLGAAAGGI 85
Query: 105 ASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYI 164
G + + GRK SL++ +P + G+ I+ A+D L GRLL G G+ S V PVYI
Sbjct: 86 LGGWLLDRSGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYI 145
Query: 165 AEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVNWRVLAILGILPCTILIPGLFFIPES 224
+EIA +RG LGS QL V GILLAY+ G + WR LA+LG +P T+++ + ++PE+
Sbjct: 146 SEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPET 205
Query: 225 PRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQRKRYWFP 284
PR+L +E ++L+ L G + E +G ++A+ L+R + P
Sbjct: 206 PRFLLTQHQYQEAMAALRFLWGSEEG----WEEPPVGAEHQGFQLAL----LRRPGIYKP 257
Query: 285 LMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAATVGLGAIQVIATGISTWLVDKS 344
L++GI L+V QQLSG+N ++FY+ SIF A SS A+V +G IQV+ T ++ ++D++
Sbjct: 258 LIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSSLASVTVGIIQVLFTAVAALIMDRA 317
Query: 345 GRRLLLLLSSSIMTVSLVVVSIAFYL-EGTVSEDSHLYKI------------LGIVSVVG 391
GRRLLL LS IM S+ F L + S SH+ + L ++V
Sbjct: 318 GRRLLLALSGVIMVFSMSAFGTYFKLTQSLPSNSSHVGLVPIAAEPVDVQVGLAWLAVGS 377
Query: 392 LVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-ANLLLTWSS 450
+ + + GF++G GPIPW++MSEI P+ +KG+A + NW ++ +T ++++
Sbjct: 378 MCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRP 437
Query: 451 GGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
G F + A +V+FT VPETKGRTLE++ + F
Sbjct: 438 YGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHF 474
>GTR8_RAT (Q9JJZ1) Solute carrier family 2, facilitated glucose
transporter, member 8 (Glucose transporter type 8)
(Glucose transporter type X1)
Length = 478
Score = 278 bits (710), Expect = 3e-74
Identities = 168/462 (36%), Positives = 254/462 (54%), Gaps = 27/462 (5%)
Query: 45 GSVSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSD----LKLSLSEFSLFGSLSNVGAM 100
G V AALGP+ FGF GYSSP ++ L+L + S FG++ +GA
Sbjct: 22 GGRRVFLATFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDTAASWFGAVVTLGAA 81
Query: 101 VGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVV 160
G + G + + GRK SL++ +P + G+ I+ A+D L GRLL G G+ S V
Sbjct: 82 AGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVA 141
Query: 161 PVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVNWRVLAILGILPCTILIPGLFF 220
PVYI+EIA +RG LGS QL V GILLAY+ G + WR LA+LG +P T+++ + +
Sbjct: 142 PVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCY 201
Query: 221 IPESPRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQRKR 280
+PE+PR+L +E ++L+ L G + E + A L+R
Sbjct: 202 MPETPRFLLTQHQYQEAMAALRFLWGSE--------EGWEEPPVGAEHQGFQLAMLRRPG 253
Query: 281 YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAATVGLGAIQVIATGISTWL 340
PL++GI L+V QQLSG+N ++FY+ +IF A SS A+V +G IQV+ T ++ +
Sbjct: 254 VHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSSLASVTVGIIQVLFTAVAALI 313
Query: 341 VDKSGRRLLLLLSSSIMTVSLVVVSIAFYL-EGTVSEDSHLYKILGI------------- 386
+D++GR+LLL LS IM S+ F L + S SH+ ++ I
Sbjct: 314 MDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAW 373
Query: 387 VSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMTANLLL 446
++V + + + GF++G GPIPW++MSEI P+ IKG+A + NW ++ +T N ++
Sbjct: 374 LAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIM 433
Query: 447 -TWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
G F + +V+FT +VPETKGRTLE+I + F
Sbjct: 434 EILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHF 475
>GTR6_HUMAN (Q9UGQ3) Solute carrier family 2, facilitated glucose
transporter, member 6 (Glucose transporter type 6)
(Glucose transporter type 9)
Length = 507
Score = 247 bits (631), Expect = 4e-65
Identities = 152/466 (32%), Positives = 256/466 (54%), Gaps = 30/466 (6%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPTQDAIVS----DLKLSLSEFSLFGSLSNVGAMVGAI 104
V A LG FG+ Y+SP A+ DL L+ S+ S FGS+ +GA G +
Sbjct: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGL 97
Query: 105 ASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYI 164
++ + + +GRK S+M +A+P+ G+ ++ A L +GR L GF G+ + +PVY+
Sbjct: 98 SAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYV 157
Query: 165 AEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVNWRVLAILGILPCTILIPGLFFIPES 224
+EIAP +RG LG+ QL G L Y LGL + WR LA+ G P I+I L F+P S
Sbjct: 158 SEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNS 217
Query: 225 PRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQRKRYWFP 284
PR+L G EE +L LRG D D+ E +I+ ++ + RV+ +A+ + P
Sbjct: 218 PRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVS--WAEARAPHVCRP 275
Query: 285 LMVGIGLLVLQQLSGINGVLFYSTSIFANAGI---SSSSAATVGLGAIQVIATGISTWLV 341
+ V + + +LQQL+GI +L Y SIF + + AA V GA+++++ I+ +
Sbjct: 276 ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIV--GAVRLLSVLIAALTM 333
Query: 342 DKSGRRLLLLLSSSIMTVSLVVVSIAFYL-------EGTVSEDSHLY-----------KI 383
D +GR++LL +S++IM + + + + + T +S +
Sbjct: 334 DLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGY 393
Query: 384 LGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-A 442
L +V ++ ++ ++G+++G GPI W++MSE+LP+ +G+A +A+WLT++ +T +
Sbjct: 394 LTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFL 453
Query: 443 NLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSFR 488
++ T+ F + + ++VFT VPETKGR+LE+I+S FR
Sbjct: 454 PVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFR 499
>GTR3_RAT (Q07647) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 493
Score = 229 bits (585), Expect = 9e-60
Identities = 146/465 (31%), Positives = 244/465 (52%), Gaps = 33/465 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLFGS 93
S++F V +A +G QFG+ G + + I L +L E +SL +
Sbjct: 9 SLVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPREGLLTTLWSLCVA 68
Query: 94 LSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGRLLEG 150
+ +VG M+G+ + G GR+ S+++ + I+G + FAK L +GRL+ G
Sbjct: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIG 128
Query: 151 FGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL-FVN-----WRVLA 204
G+ + VP+YI E++P LRG G++NQL + +GIL+A + GL F+ W L
Sbjct: 129 IFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLL 188
Query: 205 ILGILPCTILIPGLFFIPESPRWLAKMGMTEEFESSLQVLRGFDT-DISVEVHEIKRSIV 263
L I+P + L F PESPR+L + EE +++ + R + T D+ E+ E+K +
Sbjct: 189 GLTIIPAILQSAALPFCPESPRFLL-INRKEEDQATEILQRLWGTPDVIQEIQEMKDESI 247
Query: 264 PRGRRVAIRFADLQRKRYWF-PLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAA 322
+ + +L + +F PL++ + L + QQ SGIN V +YST IF +AG+ A
Sbjct: 248 RMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPIYA 307
Query: 323 TVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYK 382
T+G G + I T +S +LV+++GRR L ++ M V V ++I+ L+ Y+
Sbjct: 308 TIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDE-------YE 360
Query: 383 ILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMTA 442
+ V +V ++V V F +G GPIPW I++E+ + A + A +NW +++ + M
Sbjct: 361 AMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFF 420
Query: 443 NLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++ F ++FT+ VPETKGRT E+I +F
Sbjct: 421 PSAAAYLGAYVFIIFAAFLVFFLIFTSFKVPETKGRTFEDITRAF 465
>GTR3_MOUSE (P32037) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 493
Score = 229 bits (583), Expect = 2e-59
Identities = 151/466 (32%), Positives = 242/466 (51%), Gaps = 35/466 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLFGS 93
S++F V +A +G QFG+ G + + + L +L E +SL +
Sbjct: 9 SLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVA 68
Query: 94 LSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGRLLEG 150
+ +VG M+G+ + G GR+ S+++ + II + FAK L +GRLL G
Sbjct: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIG 128
Query: 151 FGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL-FVN-----WRVLA 204
G+ + VP+YI E++P LRG G++NQL + +GIL+A + GL F+ W L
Sbjct: 129 IFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLL 188
Query: 205 ILGILPCTILIPGLFFIPESPRWLAKMGMTEEFESS--LQVLRGFDTDISVEVHEIKRSI 262
L I+P + L F PESPR+L + EE +++ LQ L G +D+ E+ E+K
Sbjct: 189 GLTIIPAILQSAALPFCPESPRFLL-INKKEEDQATEILQRLWG-TSDVVQEIQEMKDES 246
Query: 263 VPRGRRVAIRFADLQRK-RYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSA 321
V + + +L R Y PL++ I L + QQLSGIN V +YST IF +AG+
Sbjct: 247 VRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIY 306
Query: 322 ATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLY 381
AT+G G + I T +S +LV+++GRR L ++ M V V ++I+ L+ Y
Sbjct: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDD-------Y 359
Query: 382 KILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT 441
+ + V +V +++ V F +G GPIPW I++E+ + A + A NW +++ + M
Sbjct: 360 EAMSFVCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGML 419
Query: 442 ANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++ F ++FT VPETKGRT E+I +F
Sbjct: 420 FPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDIARAF 465
>GTR3_CANFA (P47842) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 495
Score = 225 bits (574), Expect = 2e-58
Identities = 149/467 (31%), Positives = 239/467 (50%), Gaps = 33/467 (7%)
Query: 46 SVSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLF 91
+VS++F + IA +G QFG+ G + + I L +L E +SL
Sbjct: 7 TVSLIFALSIATIGSFQFGYNTGVINAPETIIKDFLNYTLEEKSENLPTEVLLTSLWSLS 66
Query: 92 GSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGRLL 148
++ +VG M+G+ + G GR+ S+++ + + G + F K L +GRL+
Sbjct: 67 VAIFSVGGMIGSFSVGLFVNRFGRRNSMLMVNLLAVAGGCLMGFCKIAQSVEMLILGRLI 126
Query: 149 EGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN------WRV 202
G G+ + VP+YI EI+P LRG G++NQL + IGIL+A + GL V W +
Sbjct: 127 IGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVIMGTEELWPL 186
Query: 203 LAILGILPCTILIPGLFFIPESPRWLAKMGMTEE-FESSLQVLRGFDTDISVEVHEIKRS 261
L I+P + L F PESPR+L EE + LQ L G D+S ++ E+K
Sbjct: 187 LLGFTIIPAVLQSAALPFCPESPRFLLINRKEEENAKEILQRLWGTQ-DVSQDIQEMKDE 245
Query: 262 IVPRGRRVAIRFADLQRKR-YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSS 320
+ + +L R R Y P+++ I L + QQLSGIN V +YST IF +AG+
Sbjct: 246 SARMAQEKQVTVLELFRSRSYRQPIIISIMLQLSQQLSGINAVFYYSTGIFKDAGVEEPI 305
Query: 321 AATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHL 380
AT+G G + I T +S +LV+++GRR L ++ M V ++++I+ L+
Sbjct: 306 YATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSILMTISLLLKDN------- 358
Query: 381 YKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITM 440
Y + V + ++V V F +G GPIPW I++E+ + A + A +NW +++ + +
Sbjct: 359 YNWMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL 418
Query: 441 TANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++T +VFT VPET+GRT EEI +F
Sbjct: 419 LFPSAAFYLGAYVFIIFTGFLIVFLVFTFFKVPETRGRTFEEITRAF 465
>GTR3_SHEEP (P47843) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 494
Score = 223 bits (569), Expect = 7e-58
Identities = 149/464 (32%), Positives = 236/464 (50%), Gaps = 33/464 (7%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLFGSL 94
++F + IA +G QFG+ G + + I L +L E +SL ++
Sbjct: 10 LIFAISIATIGSFQFGYNTGVINAPEAIIKDFLNYTLEERSETPPSSVLLTSLWSLSVAI 69
Query: 95 SNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGRLLEGF 151
+VG M+G+ + G GR+ S++I + I G + F K L +GRL+ G
Sbjct: 70 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAIAGGCLMGFCKIAESVEMLILGRLIIGL 129
Query: 152 GVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN------WRVLAI 205
G+ + VP+YI EI+P LRG G++NQL + IGIL+A + GL V W +L
Sbjct: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVILGTEDLWPLLLG 189
Query: 206 LGILPCTILIPGLFFIPESPRWLAKMGMTEE-FESSLQVLRGFDTDISVEVHEIKRSIVP 264
ILP I L F PESPR+L EE + LQ L G + D++ ++ E+K +
Sbjct: 190 FTILPAIIQCAALPFCPESPRFLLINRKEEEKAKEILQRLWGTE-DVAQDIQEMKDESMR 248
Query: 265 RGRRVAIRFADLQRK-RYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAAT 323
+ + +L R Y P+++ I L + QQLSGIN V +YST IF +AG+ AT
Sbjct: 249 MSQEKQVTVLELFRAPNYRQPIIISIMLQLSQQLSGINAVFYYSTGIFKDAGVQEPVYAT 308
Query: 324 VGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYKI 383
+G G + I T +S +LV+++GRR L L+ M ++++I+ L+ Y
Sbjct: 309 IGAGVVNTIFTVVSVFLVERAGRRTLHLIGLGGMAFCSILMTISLLLKDN-------YSW 361
Query: 384 LGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMTAN 443
+ + + ++V V F +G GPIPW I++E+ + A + A +NW +++ + +
Sbjct: 362 MSFICIGAILVFVAFFEIGPGPIPWFIVAELFGQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
Query: 444 LLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++TV VFT VPET+GRT EEI +F
Sbjct: 422 SATFYLGAYVFIVFTVFLVIFWVFTFFKVPETRGRTFEEITRAF 465
>GTR3_BOVIN (P58352) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 494
Score = 221 bits (564), Expect = 3e-57
Identities = 148/464 (31%), Positives = 235/464 (49%), Gaps = 33/464 (7%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLFGSL 94
++F + +A +G QFG+ G + + I L +L E +SL ++
Sbjct: 10 LIFAISVATIGSFQFGYNTGVINAPEAIIKDFLNYTLEERSEPPPSSVLLTSLWSLSVAI 69
Query: 95 SNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGRLLEGF 151
+VG M+G+ + G GR S++I + I G + F K L +GRL+ G
Sbjct: 70 FSVGGMIGSFSVGLFVNRFGRGNSMLIVNLLAIAGGCLMGFCKIAESVEMLILGRLIIGL 129
Query: 152 GVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN------WRVLAI 205
G+ + VP+YI EI+P LRG G++NQL + IGIL+A + GL V W +L
Sbjct: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVILGTEDLWPLLLG 189
Query: 206 LGILPCTILIPGLFFIPESPRWLAKMGMTEE-FESSLQVLRGFDTDISVEVHEIKRSIVP 264
ILP I L F PESPR+L EE + LQ L G + D++ ++ E+K +
Sbjct: 190 FTILPAIIQCAALPFCPESPRFLLINRKEEEKAKEILQRLWGTE-DVAQDIQEMKDESMR 248
Query: 265 RGRRVAIRFADLQRK-RYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAAT 323
+ + +L R Y P+++ I L + QQLSGIN V +YST IF +AG+ AT
Sbjct: 249 MSQEKQVTVLELFRAPNYRQPIIISIMLQLSQQLSGINAVFYYSTGIFKDAGVQEPVYAT 308
Query: 324 VGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYKI 383
+G G + I T +S +LV+++GRR L L+ M ++++I+ L+ Y
Sbjct: 309 IGAGVVNTIFTVVSVFLVERAGRRTLHLIGLGGMAFCSILMTISLLLKDN-------YSW 361
Query: 384 LGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMTAN 443
+ + + ++V V F +G GPIPW I++E+ + A + A +NW +++ + +
Sbjct: 362 MSFICIGAILVFVAFFEIGPGPIPWFIVAELFGQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
Query: 444 LLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++TV VFT VPET+GRT EEI +F
Sbjct: 422 SAAFYLGAYVFIVFTVFLVIFWVFTFFKVPETRGRTFEEITRAF 465
>XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose
transporter)
Length = 457
Score = 221 bits (562), Expect = 4e-57
Identities = 142/451 (31%), Positives = 241/451 (52%), Gaps = 20/451 (4%)
Query: 47 VSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSEFSLFGSLSNVGAMVGAIAS 106
VS F ALG + FG+ G S I + L + S +GA++GA
Sbjct: 4 VSTGFVYFFGALGGLLFGYDTGVISGAILFIQKQMNLGSWQQGWVVSAVLLGAILGAAII 63
Query: 107 GQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYIAE 166
G ++ GR+ L+++AI +G L +F+ ++ L + R++ G VG S ++P Y+AE
Sbjct: 64 GPSSDRFGRRKLLLLSAIIFFVGALGSAFSPEFWTLIISRIILGMAVGAASALIPTYLAE 123
Query: 167 IAPENLRGGLGSVNQLSVTIGILLAYLL-----GLFVNWRVLAILGILPCTILIPGLFFI 221
+AP + RG + S+ QL V GILLAY+ G + WR + +P +L G +
Sbjct: 124 LAPSDKRGTVSSLFQLMVMTGILLAYITNYSFSGFYTGWRWMLGFAAIPAALLFLGGLIL 183
Query: 222 PESPRWLAKMGMTEEFESSLQVLRGFD-TDISVEVHEIKRSIVPRGRRVAIRFADLQRKR 280
PESPR+L K G +E L + D ++ E+++I+ S + V+ +++L K
Sbjct: 184 PESPRFLVKSGHLDEARHVLDTMNKHDQVAVNKEINDIQES----AKIVSGGWSELFGKM 239
Query: 281 YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSA--ATVGLGAIQVIATGIST 338
L++GIGL + QQ+ G N VL+Y+ +IF + G S+A A +G+G VI T I+
Sbjct: 240 VRPSLIIGIGLAIFQQVMGCNTVLYYAPTIFTDVGFGVSAALLAHIGIGIFNVIVTAIAV 299
Query: 339 WLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYKILGIVSVVGLVVMVIG 398
++DK R+ ++ + + M +SL V+SI G + I+SV+ L V +
Sbjct: 300 AIMDKIDRKKIVNIGAVGMGISLFVMSIGMKFSGG-------SQTAAIISVIALTVYIAF 352
Query: 399 FSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-ANLLLTWSSGGTFTMY 457
FS GP+ WV++ E+ P++I+GL S A++ NW + +++T +LL + +G F Y
Sbjct: 353 FSATWGPVMWVMIGEVFPLNIRGLGNSFASVINWTANMIVSLTFPSLLDFFGTGSLFIGY 412
Query: 458 TVVAAFTVVFTALWVPETKGRTLEEIQSSFR 488
++ ++ F V ET+ R+LE+I+++ R
Sbjct: 413 GILCFASIWFVQKKVFETRNRSLEDIEATLR 443
>GTR2_HUMAN (P11168) Solute carrier family 2, facilitated glucose
transporter, member 2 (Glucose transporter type 2,
liver)
Length = 524
Score = 220 bits (560), Expect = 7e-57
Identities = 138/426 (32%), Positives = 232/426 (54%), Gaps = 19/426 (4%)
Query: 74 QDAIVSDLKLSLSEFSLFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAI 133
++ V+ +L +SL S VG M + G + + +GR ++++A I +++G L +
Sbjct: 83 EEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLM 142
Query: 134 SFAK---DYSFLYMGRLLEGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILL 190
F+K + + GR + G G+IS +VP+YI EIAP LRG LG+ +QL++ GIL+
Sbjct: 143 GFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILI 202
Query: 191 AYLLGL------FVNWRVLAILGILPCTILIPGLFFIPESPRWL-AKMGMTEEFESSLQV 243
+ ++GL + W +L L + + LFF PESPR+L K+ + + SL+
Sbjct: 203 SQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKR 262
Query: 244 LRGFDTDISVEVHEIKRSIVPRGRRVAIRFADL-QRKRYWFPLMVGIGLLVLQQLSGING 302
LRG+D D++ +++E+++ + L Y P++V + L V QQ SGING
Sbjct: 263 LRGYD-DVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGING 321
Query: 303 VLFYSTSIFANAGISSSSAATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLV 362
+ +YSTSIF AGIS AT+G+GA+ ++ T +S +LV+K+GRR L L+ S M V +
Sbjct: 322 IFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAI 381
Query: 363 VVSIAFYLEGTVSEDSHLYKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGL 422
+S+ L S S+ VS++ + + V F +G GPIPW +++E +
Sbjct: 382 FMSVGLVLLNKFSWMSY-------VSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPA 434
Query: 423 AGSTATMANWLTSWAITMTANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEE 482
A + A +NW ++ + + + + F ++ V +FT VPETKG++ EE
Sbjct: 435 ALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEE 494
Query: 483 IQSSFR 488
I + F+
Sbjct: 495 IAAEFQ 500
>GTR3_CHICK (P28568) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3)
(CEF-GT3)
Length = 496
Score = 219 bits (559), Expect = 1e-56
Identities = 148/467 (31%), Positives = 239/467 (50%), Gaps = 35/467 (7%)
Query: 46 SVSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLF 91
+ S+++ V +AA+G +QFG+ G + + I + +LS+ +SL
Sbjct: 8 TASLIYAVSVAAIGSLQFGYNTGVINAPEKIIQAFYNRTLSQRSGETISPELLTSLWSLS 67
Query: 92 GSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGW--LAIS-FAKDYSFLYMGRLL 148
++ +VG M+G+ + GR+ S+++ + G +A+S AK L +GR +
Sbjct: 68 VAIFSVGGMIGSFSVSLFFNRFGRRNSMLLVNVLAFAGGALMALSKIAKAVEMLIIGRFI 127
Query: 149 EGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLF------VNWRV 202
G G+ + VP+YI+E++P +LRG G++NQL + +GIL+A + GL W +
Sbjct: 128 IGLFCGLCTGFVPMYISEVSPTSLRGAFGTLNQLGIVVGILVAQIFGLEGIMGTEALWPL 187
Query: 203 LAILGILPCTILIPGLFFIPESPRWLAKMGMTEE-FESSLQVLRGFDTDISVEVHEIKRS 261
L I+P + L F PESPR+L M EE ++ LQ LRG D+S ++ E+K
Sbjct: 188 LLGFTIVPAVLQCVALLFCPESPRFLLINKMEEEKAQTVLQKLRGTQ-DVSQDISEMKEE 246
Query: 262 IVPRGRRVAIRFADLQRK-RYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSS 320
+ +L R Y P+++ I L + QQLSGIN V +YST IF AGI+
Sbjct: 247 SAKMSQEKKATVLELFRSPNYRQPIIISITLQLSQQLSGINAVFYYSTGIFERAGITQPV 306
Query: 321 AATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHL 380
AT+G G + + T +S +LV+++GRR L L+ M V V++IA L+
Sbjct: 307 YATIGAGVVNTVFTVVSLFLVERAGRRTLHLVGLGGMAVCAAVMTIALALK------EKW 360
Query: 381 YKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITM 440
+ + IV+ G V + F +G GPIPW I++E+ + A + A +NW +++ + M
Sbjct: 361 IRYISIVATFGFVAL---FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGM 417
Query: 441 TANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
F ++ V +FT VPETKGRT E+I F
Sbjct: 418 LFPYAEKLCGPYVFLIFLVFLLIFFIFTYFKVPETKGRTFEDISRGF 464
>CSBC_BACSU (P46333) Probable metabolite transport protein csbC
Length = 461
Score = 218 bits (554), Expect = 4e-56
Identities = 139/439 (31%), Positives = 236/439 (53%), Gaps = 18/439 (4%)
Query: 57 ALGPIQFGFTCGYSSPTQDAIVSDLKLSLSEFSLFGSLSNVGAMVGAIASGQIAEYVGRK 116
ALG + +G+ G S I +D+ L+ L S+ +GA+ G+ SG ++ GR+
Sbjct: 15 ALGGLLYGYDTGVISGALLFINNDIPLTTLTEGLVVSMLLLGAIFGSALSGTCSDRWGRR 74
Query: 117 GSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYIAEIAPENLRGGL 176
+ + +I IIG LA +F++ L R++ G VG + +VPVY++E+AP +RG L
Sbjct: 75 KVVFVLSIIFIIGALACAFSQTIGMLIASRVILGLAVGGSTALVPVYLSEMAPTKIRGTL 134
Query: 177 GSVNQLSVTIGILLAYLLGL----FVNWRVLAILGILPCTILIPGLFFIPESPRWLAKMG 232
G++N L + GILLAY++ F WR + L +P +L+ G+ F+PESPRWL K G
Sbjct: 135 GTMNNLMIVTGILLAYIVNYLFTPFEAWRWMVGLAAVPAVLLLIGIAFMPESPRWLVKRG 194
Query: 233 MTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQRKRYWFPLMVGIGLL 292
EE + + DI +E+ E+K+ + L+ K L++G+GL
Sbjct: 195 SEEEARRIMNITHD-PKDIEMELAEMKQG---EAEKKETTLGVLKAKWIRPMLLIGVGLA 250
Query: 293 VLQQLSGINGVLFYSTSIFANAGISSSSAA--TVGLGAIQVIATGISTWLVDKSGRRLLL 350
+ QQ GIN V++Y+ +IF AG+ +S++A T+G+G + VI + L+D+ GR+ LL
Sbjct: 251 IFQQAVGINTVIYYAPTIFTKAGLGTSASALGTMGIGILNVIMCITAMILIDRVGRKKLL 310
Query: 351 LLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYKILGIVSVVGLVVMVIGFSLGLGPIPWVI 410
+ S +T+SL +S G + + + +VV L V ++ + GP+ WV+
Sbjct: 311 IWGSVGITLSLAALSGVLLTLGLSASTAWM-------TVVFLGVYIVFYQATWGPVVWVL 363
Query: 411 MSEILPVSIKGLAGSTATMANWLTSWAITMTANLLLT-WSSGGTFTMYTVVAAFTVVFTA 469
M E+ P +G A T+ + +++ L+L+ F +++V+ + F
Sbjct: 364 MPELFPSKARGAATGFTTLVLSAANLIVSLVFPLMLSAMGIAWVFMVFSVICLLSFFFAF 423
Query: 470 LWVPETKGRTLEEIQSSFR 488
VPETKG++LEEI++S +
Sbjct: 424 YMVPETKGKSLEEIEASLK 442
>ITR1_YEAST (P30605) Myo-inositol transporter 1
Length = 584
Score = 216 bits (550), Expect = 1e-55
Identities = 149/481 (30%), Positives = 255/481 (52%), Gaps = 35/481 (7%)
Query: 32 SSVMGSTTQVMRDGSVSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLK---LSLSEF 88
+SVM + Q + +++ F +A++ FG+ GY S +I +DL L+ E
Sbjct: 72 TSVMITFNQSLSPFIITLTF---VASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEK 128
Query: 89 SLFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLL 148
+ + +++GA++ +I +G A+ GRK LM + + +IG + A + + +GRL+
Sbjct: 129 EIVTAATSLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLI 188
Query: 149 EGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN-----WRVL 203
GFGVGI S + P++I+EIAP+ +RG L +N L +T G L+AY G +N WR+L
Sbjct: 189 MGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRIL 248
Query: 204 AILGILPCTILIPGLFFIPESPRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIK---- 259
L ++P + L F+P++PR+ G + + +VL+ TD S E+ E K
Sbjct: 249 VGLSLIPTAVQFTCLCFLPDTPRYYVMKG---DLARATEVLKRSYTDTSEEIIERKVEEL 305
Query: 260 ---RSIVPRGRRVAIRFADLQRKRYWFP-----LMVGIGLLVLQQLSGINGVLFYSTSIF 311
+P G+ V + + ++ + P L++G GL +QQ +G N ++++S +IF
Sbjct: 306 VTLNQSIP-GKNVPEKVWNTIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIF 364
Query: 312 ANAGISSSSAATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLE 371
G +SSA ++ + I T ++ + +DK GRR +LL+ MT++LVV SIAF+
Sbjct: 365 ETVGFKNSSAVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFL 424
Query: 372 GTVSED------SHLYKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGS 425
G + S + GIV +V ++V ++LG+G +PW SE+ P +++G+ S
Sbjct: 425 GIKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYALGIGTVPWQ-QSELFPQNVRGIGTS 483
Query: 426 TATMANWLTSWAITMT-ANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQ 484
AT NW S I T +L + GTF + ++ + +F PE G LEE+Q
Sbjct: 484 YATATNWAGSLVIASTFLTMLQNITPAGTFAFFAGLSCLSTIFCYFCYPELSGLELEEVQ 543
Query: 485 S 485
+
Sbjct: 544 T 544
>GTR4_MOUSE (P14142) Solute carrier family 2, facilitated glucose
transporter, member 4 (Glucose transporter type 4,
insulin-responsive) (GT2)
Length = 509
Score = 215 bits (548), Expect = 2e-55
Identities = 148/470 (31%), Positives = 243/470 (51%), Gaps = 37/470 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLS------------------LSEFS 89
+++ V A LG +QFG+ G + Q I + + ++
Sbjct: 23 TLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNATWLGRQGPGGPDSIPQGTLTTLWA 82
Query: 90 LFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGR 146
L ++ +VG M+ + G I++++GRK +++ + ++G + A Y L +GR
Sbjct: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVLGGALMGLANAVASYEILILGR 142
Query: 147 LLEGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL------FVNW 200
L G G+ S +VP+Y+ EIAP +LRG LG++NQL++ IGIL+A +LGL W
Sbjct: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILVAQVLGLESMLGTATLW 202
Query: 201 RVLAILGILPCTILIPGLFFIPESPRWLAKMGMTE-EFESSLQVLRGFDTDISVEVHEIK 259
+L L +LP + + L F PESPR+L + E SL+ L G+ D+S + E+K
Sbjct: 203 PLLLALTVLPALLQLILLPFCPESPRYLYIIRNLEGPARKSLKRLTGW-ADVSDALAELK 261
Query: 260 RSIVPRGRRVAIRFADLQRKR-YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISS 318
R + L R + PL++ + L + QQLSGIN V +YSTSIF +AG+
Sbjct: 262 DEKRKLERERPMSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFESAGVGQ 321
Query: 319 SSAATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDS 378
+ AT+G G + + T +S LV+++GRR L LL + M +++++A L V S
Sbjct: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMS 381
Query: 379 HLYKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAI 438
+ VS+V + V F +G GPIPW I++E+ + A + A +NW ++ +
Sbjct: 382 Y-------VSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTCNFIV 434
Query: 439 TMTANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSFR 488
M + F ++ V+ +FT L VPET+GRT ++I ++FR
Sbjct: 435 GMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLKVPETRGRTFDQISAAFR 484
>GTR4_RAT (P19357) Solute carrier family 2, facilitated glucose
transporter, member 4 (Glucose transporter type 4,
insulin-responsive)
Length = 509
Score = 214 bits (544), Expect = 5e-55
Identities = 147/470 (31%), Positives = 242/470 (51%), Gaps = 37/470 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLS------------------LSEFS 89
+++ V A LG +QFG+ G + Q I + + ++
Sbjct: 23 TLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNATWLGRQGPGGPDSIPQGTLTTLWA 82
Query: 90 LFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGR 146
L ++ +VG M+ + G I++++GRK +++ + ++G + A Y L +GR
Sbjct: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVLGGALMGLANAAASYEILILGR 142
Query: 147 LLEGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL------FVNW 200
L G G+ S +VP+Y+ EIAP +LRG LG++NQL++ IGIL+A +LGL W
Sbjct: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILVAQVLGLESMLGTATLW 202
Query: 201 RVLAILGILPCTILIPGLFFIPESPRWLAKMGMTE-EFESSLQVLRGFDTDISVEVHEIK 259
+L + +LP + + L F PESPR+L + E SL+ L G+ D+S + E+K
Sbjct: 203 PLLLAITVLPALLQLLLLPFCPESPRYLYIIRNLEGPARKSLKRLTGW-ADVSDALAELK 261
Query: 260 RSIVPRGRRVAIRFADLQRKR-YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISS 318
R + L R + PL++ + L + QQLSGIN V +YSTSIF AG+
Sbjct: 262 DEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFELAGVEQ 321
Query: 319 SSAATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDS 378
+ AT+G G + + T +S LV+++GRR L LL + M +++++A L V S
Sbjct: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPSMS 381
Query: 379 HLYKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAI 438
+ VS+V + V F +G GPIPW I++E+ + A + A +NW ++ +
Sbjct: 382 Y-------VSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTCNFIV 434
Query: 439 TMTANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSFR 488
M + F ++ V+ +FT L VPET+GRT ++I ++FR
Sbjct: 435 GMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISATFR 484
>GTR4_HUMAN (P14672) Solute carrier family 2, facilitated glucose
transporter, member 4 (Glucose transporter type 4,
insulin-responsive)
Length = 509
Score = 213 bits (543), Expect = 7e-55
Identities = 148/469 (31%), Positives = 243/469 (51%), Gaps = 37/469 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLS------------------LSEFS 89
+++ V A LG +QFG+ G + Q I + + ++
Sbjct: 23 TLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWA 82
Query: 90 LFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAK---DYSFLYMGR 146
L ++ +VG M+ + G I++++GRK ++++ + ++G + A Y L +GR
Sbjct: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142
Query: 147 LLEGFGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL------FVNW 200
L G G+ S +VP+Y+ EIAP +LRG LG++NQL++ IGIL+A +LGL W
Sbjct: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202
Query: 201 RVLAILGILPCTILIPGLFFIPESPRWLAKMGMTE-EFESSLQVLRGFDTDISVEVHEIK 259
+L L +LP + + L F PESPR+L + E SL+ L G+ D+S + E+K
Sbjct: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGW-ADVSGVLAELK 261
Query: 260 RSIVPRGRRVAIRFADLQRKR-YWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISS 318
R + L R + PL++ + L + QQLSGIN V +YSTSIF AG+
Sbjct: 262 DEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQ 321
Query: 319 SSAATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDS 378
+ AT+G G + + T +S LV+++GRR L LL + M +++++A L V S
Sbjct: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMS 381
Query: 379 HLYKILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAI 438
+ VS+V + V F +G GPIPW I++E+ + A + A +NW +++ I
Sbjct: 382 Y-------VSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFII 434
Query: 439 TMTANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
M + F ++ V+ +FT L VPET+GRT ++I ++F
Sbjct: 435 GMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483
>ITR2_YEAST (P30606) Myo-inositol transporter 2
Length = 612
Score = 212 bits (540), Expect = 2e-54
Identities = 141/463 (30%), Positives = 244/463 (52%), Gaps = 30/463 (6%)
Query: 49 VLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLK---LSLSEFSLFGSLSNVGAMVGAIA 105
++ +A++ FG+ GY S +I DL L+ E L + +++GA++ ++
Sbjct: 112 IITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSLGALITSVG 171
Query: 106 SGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPVYIA 165
+G A+ GR+ LM + + +IG + A + + GRL+ GFGVGI S + P++I+
Sbjct: 172 AGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFIS 231
Query: 166 EIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN-----WRVLAILGILPCTILIPGLFF 220
EIAP+ +RG L +N L +T G L+AY G +N WR+L L ++P + F
Sbjct: 232 EIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCF 291
Query: 221 IPESPRWLAKMGMTEEFESSLQ--VLRGFDTDISVEVHEIK--RSIVPRGRRVAIRFADL 276
+P++PR+ G + + L+ + D I +V E+ +P G+ +F ++
Sbjct: 292 LPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIP-GKNPITKFWNM 350
Query: 277 QRKRYWFP-----LMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSAATVGLGAIQV 331
++ + P L++G GL +QQ +G N ++++S +IF G +SSA ++ +
Sbjct: 351 VKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNF 410
Query: 332 IATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEG--------TVSEDSHLYKI 383
+ T I+ + +DK GRR +LL+ MTV+LV+ +IAF+ G V+ D +
Sbjct: 411 VFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDG--FSS 468
Query: 384 LGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-A 442
GIV +V ++V ++LG+G +PW SE+ P +++G+ S AT NW S I T
Sbjct: 469 WGIVIIVFIIVYAAFYALGIGTVPWQ-QSELFPQNVRGVGTSYATATNWAGSLVIASTFL 527
Query: 443 NLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQS 485
+L + GTF+ + VA + +F PE G LEE+Q+
Sbjct: 528 TMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQT 570
>GALP_ECOLI (P37021) Galactose-proton symporter (Galactose
transporter)
Length = 464
Score = 211 bits (538), Expect = 3e-54
Identities = 141/450 (31%), Positives = 233/450 (51%), Gaps = 18/450 (4%)
Query: 43 RDGSVSVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSEFSLFGSLSNVGAMVG 102
R F +AAL + FG G + I + +++ S GA VG
Sbjct: 9 RSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIADEFQITSHTQEWVVSSMMFGAAVG 68
Query: 103 AIASGQIAEYVGRKGSLMIAAIPNIIGWLAISFAKDYSFLYMGRLLEGFGVGIISYVVPV 162
A+ SG ++ +GRK SLMI AI + G L + A + L + R+L G VG+ SY P+
Sbjct: 69 AVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAAPNVEVLILSRVLLGLAVGVASYTAPL 128
Query: 163 YIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGLFVN----WRVLAILGILPCTILIPGL 218
Y++EIAPE +RG + S+ QL +TIGIL AYL + WR + + I+P +L+ G+
Sbjct: 129 YLSEIAPEKIRGSMISMYQLMITIGILGAYLSDTAFSYTGAWRWMLGVIIIPAILLLIGV 188
Query: 219 FFIPESPRWLAKMGMTEEFESSLQVLRGFDTDISVEVHEIKRSIVPRGRRVAIRFADLQR 278
FF+P+SPRW A + E L LR + E+ EI+ S+ + A+ +
Sbjct: 189 FFLPDSPRWFAAKRRFVDAERVLLRLRDTSAEAKRELDEIRESLQVKQSGWALFKENSNF 248
Query: 279 KRYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSA---ATVGLGAIQVIATG 335
+R F +G+ L V+QQ +G+N +++Y+ IF AG ++++ TV +G V+AT
Sbjct: 249 RRAVF---LGVLLQVMQQFTGMNVIMYYAPKIFELAGYTNTTEQMWGTVIVGLTNVLATF 305
Query: 336 ISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLYKILGIVSVVGLVVM 395
I+ LVD+ GR+ L L +M + V+ ++ G S + + ++ L++
Sbjct: 306 IAIGLVDRWGRKPTLTLGFLVMAAGMGVLGTMMHI-GIHSPSAQYF------AIAMLLMF 358
Query: 396 VIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT-ANLLLTWSSGGTF 454
++GF++ GP+ WV+ SEI P+ + + +T NW+ + + T +L T + TF
Sbjct: 359 IVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTATNWIANMIVGATFLTMLNTLGNANTF 418
Query: 455 TMYTVVAAFTVVFTALWVPETKGRTLEEIQ 484
+Y + ++ T VPETK +LE I+
Sbjct: 419 WVYAALNVLFILLTLWLVPETKHVSLEHIE 448
>GTR3_HUMAN (P11169) Solute carrier family 2, facilitated glucose
transporter, member 3 (Glucose transporter type 3,
brain)
Length = 496
Score = 211 bits (537), Expect = 3e-54
Identities = 138/466 (29%), Positives = 238/466 (50%), Gaps = 35/466 (7%)
Query: 48 SVLFCVLIAALGPIQFGFTCGYSSPTQDAIVSDLKLSLSE--------------FSLFGS 93
+++F + +A +G QFG+ G + + I + +L++ +SL +
Sbjct: 9 ALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68
Query: 94 LSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLAISF---AKDYSFLYMGRLLEG 150
+ +VG M+G+ + G GR+ S++I + + G + AK L +GRL+ G
Sbjct: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
Query: 151 FGVGIISYVVPVYIAEIAPENLRGGLGSVNQLSVTIGILLAYLLGL-FVN-----WRVLA 204
G+ + VP+YI EI+P LRG G++NQL + +GIL+A + GL F+ W +L
Sbjct: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188
Query: 205 ILGILPCTILIPGLFFIPESPRWLAKMGMTEEFESSLQVLRGF--DTDISVEVHEIKRSI 262
ILP + L F PESPR+L + +E E++ Q+L+ D+S ++ E+K
Sbjct: 189 GFTILPAILQSAALPFCPESPRFL--LINRKEEENAKQILQRLWGTQDVSQDIQEMKDES 246
Query: 263 VPRGRRVAIRFADLQR-KRYWFPLMVGIGLLVLQQLSGINGVLFYSTSIFANAGISSSSA 321
+ + +L R Y P+++ I L + QQLSGIN V +YST IF +AG+
Sbjct: 247 ARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIY 306
Query: 322 ATVGLGAIQVIATGISTWLVDKSGRRLLLLLSSSIMTVSLVVVSIAFYLEGTVSEDSHLY 381
AT+G G + I T +S +LV+++GRR L ++ M +++++ L+ Y
Sbjct: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDN-------Y 359
Query: 382 KILGIVSVVGLVVMVIGFSLGLGPIPWVIMSEILPVSIKGLAGSTATMANWLTSWAITMT 441
+ V + ++V V F +G GPIPW I++E+ + A + A +NW +++ + +
Sbjct: 360 NGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLL 419
Query: 442 ANLLLTWSSGGTFTMYTVVAAFTVVFTALWVPETKGRTLEEIQSSF 487
+ F ++T + FT VPET+GRT E+I +F
Sbjct: 420 FPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.324 0.139 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,172,219
Number of Sequences: 164201
Number of extensions: 2171018
Number of successful extensions: 6738
Number of sequences better than 10.0: 270
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 5938
Number of HSP's gapped (non-prelim): 364
length of query: 488
length of database: 59,974,054
effective HSP length: 114
effective length of query: 374
effective length of database: 41,255,140
effective search space: 15429422360
effective search space used: 15429422360
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Lotus: description of TM0283.13