BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0280a.7
(121 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SUV4_ARATH (Q8GZB6) Histone-lysine N-methyltransferase, H3 lysin... 73 1e-13
BAT8_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysin... 37 0.008
BAT8_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysin... 37 0.008
HMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysin... 36 0.018
SUV9_ARATH (Q9T0G7) Probable histone-lysine N-methyltransferase,... 33 0.11
SUV3_ARATH (Q9C5P4) Histone-lysine N-methyltransferase, H3 lysin... 32 0.19
SUV5_ARATH (O82175) Histone-lysine N-methyltransferase, H3 lysin... 32 0.25
SUV2_ARATH (O22781) Probable histone-lysine N-methyltransferase,... 32 0.25
SUV6_ARATH (Q8VZ17) Histone-lysine N-methyltransferase, H3 lysin... 32 0.33
SU91_MOUSE (O54864) Histone-lysine N-methyltransferase, H3 lysin... 30 0.74
SU91_HUMAN (O43463) Histone-lysine N-methyltransferase, H3 lysin... 30 0.96
SUV1_ARATH (Q9FF80) Histone-lysine N-methyltransferase, H3 lysin... 29 1.6
YLK1_SCHPO (Q9P7H8) Hypothetical protein C1782.01 in chromosome I 29 2.1
SETB_MOUSE (O88974) Histone-lysine N-methyltransferase, H3 lysin... 29 2.1
SETB_HUMAN (Q15047) Histone-lysine N-methyltransferase, H3 lysin... 29 2.1
SU92_HUMAN (Q9H5I1) Histone-lysine N-methyltransferase, H3 lysin... 28 2.8
SEB2_HUMAN (Q96T68) Probable histone-lysine N-methyltransferase,... 28 2.8
GSHB_WIGBR (Q8D335) Glutathione synthetase (EC 6.3.2.3) (Glutath... 28 4.8
DEOB_CLOAB (Q97HE6) Phosphopentomutase (EC 5.4.2.7) (Phosphodeox... 28 4.8
SU92_MOUSE (Q9EQQ0) Histone-lysine N-methyltransferase, H3 lysin... 27 6.2
>SUV4_ARATH (Q8GZB6) Histone-lysine N-methyltransferase, H3 lysine-9
specific 4 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 4) (H3-K9-HMTase 4) (Suppressor of
variegation 3-9 homolog 4) (Su(var)3-9 homolog 4)
(KRYPTONITE protein)
Length = 624
Score = 72.8 bits (177), Expect = 1e-13
Identities = 38/99 (38%), Positives = 61/99 (61%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVELVIDSVSECGFE 82
NR SQK L++ L+V+ KGWAV + ++I G+PV EY+ +R+ ++ S +E FE
Sbjct: 437 NRTSQKRLRFNLEVFRSAKKGWAVRSWEYIPAGSPVCEYIGVVRRTADVDTISDNEYIFE 496
Query: 83 IDCLKIINEVEGRNRLLHNVSLPASFCVERSVDDEETME 121
IDC + + + GR R L +V++P + V +S +DE E
Sbjct: 497 IDCQQTMQGLGGRQRRLRDVAVPMNNGVSQSSEDENAPE 535
>BAT8_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9
specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase
3) (H3-K9-HMTase 3) (HLA-B associated transcript 8) (G9a)
(NG36)
Length = 1263
Score = 37.0 bits (84), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%)
Query: 18 WT*FDNRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVELVIDSVS 77
W NR+ Q ++ LQ+Y GW V I GT + EYV EL + E +
Sbjct: 1077 WRSCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDD 1136
Query: 78 ECGFEID 84
F++D
Sbjct: 1137 SYLFDLD 1143
>BAT8_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9
specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase
3) (H3-K9-HMTase 3) (HLA-B associated transcript 8) (G9a)
(NG36)
Length = 1210
Score = 37.0 bits (84), Expect = 0.008
Identities = 21/67 (31%), Positives = 30/67 (44%)
Query: 18 WT*FDNRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVELVIDSVS 77
W NR+ Q ++ LQ+Y GW V I GT + EYV EL + E +
Sbjct: 1024 WRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDD 1083
Query: 78 ECGFEID 84
F++D
Sbjct: 1084 SYLFDLD 1090
>HMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9
specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase
5) (H3-K9-HMTase 5) (Euchromatic histone
methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1)
(GLP1)
Length = 1267
Score = 35.8 bits (81), Expect = 0.018
Identities = 23/67 (34%), Positives = 31/67 (45%)
Query: 18 WT*FDNRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVELVIDSVS 77
W NR+ Q L+ LQ+Y GW V + I GT V EYV EL + E +
Sbjct: 1081 WRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREED 1140
Query: 78 ECGFEID 84
F++D
Sbjct: 1141 SYLFDLD 1147
>SUV9_ARATH (Q9T0G7) Probable histone-lysine N-methyltransferase, H3
lysine-9 specific 9 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 9) (H3-K9-HMTase 9) (Suppressor of
variegation 3-9 homolog 9) (Su(var)3-9 homolog 9)
Length = 650
Score = 33.1 bits (74), Expect = 0.11
Identities = 14/39 (35%), Positives = 23/39 (58%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEY 61
NR++QK L+ L+V+ + GW V + D + G + EY
Sbjct: 484 NRVTQKGLRNRLEVFRSLETGWGVRSLDVLHAGAFICEY 522
>SUV3_ARATH (Q9C5P4) Histone-lysine N-methyltransferase, H3 lysine-9
specific 3 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 3) (H3-K9-HMTase 3) (Suppressor of
variegation 3-9 homolog 3) (Su(var)3-9 homolog 3)
Length = 669
Score = 32.3 bits (72), Expect = 0.19
Identities = 15/49 (30%), Positives = 28/49 (56%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVEL 71
NR+ Q L+ L+V+ ++GW + + D + G+ + EY E++ N L
Sbjct: 485 NRVIQTGLKSRLEVFKTRNRGWGLRSWDSLRAGSFICEYAGEVKDNGNL 533
>SUV5_ARATH (O82175) Histone-lysine N-methyltransferase, H3 lysine-9
specific 5 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 5) (H3-K9-HMTase 5) (Suppressor of
variegation 3-9 homolog 5) (Su(var)3-9 homolog 5)
Length = 794
Score = 32.0 bits (71), Expect = 0.25
Identities = 14/42 (33%), Positives = 25/42 (59%)
Query: 24 RISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKEL 65
R+SQ ++ L+++ S+GW V + + I G+ + EY EL
Sbjct: 639 RVSQHGIKIKLEIFKTESRGWGVRSLESIPIGSFICEYAGEL 680
>SUV2_ARATH (O22781) Probable histone-lysine N-methyltransferase, H3
lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of
variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
Length = 651
Score = 32.0 bits (71), Expect = 0.25
Identities = 15/39 (38%), Positives = 22/39 (55%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEY 61
+R++QK L+ L+V+ GW V T D I G + EY
Sbjct: 486 SRVTQKGLRNRLEVFRSKETGWGVRTLDLIEAGAFICEY 524
>SUV6_ARATH (Q8VZ17) Histone-lysine N-methyltransferase, H3 lysine-9
specific 6 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 6) (H3-K9-HMTase 6) (Suppressor of
variegation 3-9 homolog 6) (Su(var)3-9 homolog 6)
Length = 790
Score = 31.6 bits (70), Expect = 0.33
Identities = 15/47 (31%), Positives = 27/47 (56%)
Query: 24 RISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVE 70
R++Q ++ L+++ S+GW V I G+ + EYV EL ++ E
Sbjct: 608 RVTQHGIKLPLEIFKTKSRGWGVRCLKSIPIGSFICEYVGELLEDSE 654
>SU91_MOUSE (O54864) Histone-lysine N-methyltransferase, H3 lysine-9
specific 1 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of
variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
(Position-effect variegation 3-9 homolog)
Length = 412
Score = 30.4 bits (67), Expect = 0.74
Identities = 16/44 (36%), Positives = 26/44 (58%), Gaps = 1/44 (2%)
Query: 23 NRISQKDLQYCLQVY-LKISKGWAVNTRDFILFGTPVLEYVKEL 65
NR+ QK ++Y L ++ +GW V T + I + V+EYV E+
Sbjct: 234 NRVVQKGIRYDLCIFRTNDGRGWGVRTLEKIRKNSFVMEYVGEI 277
>SU91_HUMAN (O43463) Histone-lysine N-methyltransferase, H3 lysine-9
specific 1 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of
variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
Length = 412
Score = 30.0 bits (66), Expect = 0.96
Identities = 16/44 (36%), Positives = 26/44 (58%), Gaps = 1/44 (2%)
Query: 23 NRISQKDLQYCLQVY-LKISKGWAVNTRDFILFGTPVLEYVKEL 65
NR+ QK ++Y L ++ +GW V T + I + V+EYV E+
Sbjct: 234 NRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
>SUV1_ARATH (Q9FF80) Histone-lysine N-methyltransferase, H3 lysine-9
specific 1 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of
variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
Length = 670
Score = 29.3 bits (64), Expect = 1.6
Identities = 16/68 (23%), Positives = 35/68 (50%), Gaps = 1/68 (1%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKELRKNVELVIDSVSECGFE 82
N+++Q ++ L+V+ ++GW + + D I G+ + YV E K+ V +++ +
Sbjct: 486 NKVTQMGVKVRLEVFKTANRGWGLRSWDAIRAGSFICIYVGE-AKDKSKVQQTMANDDYT 544
Query: 83 IDCLKIIN 90
D + N
Sbjct: 545 FDTTNVYN 552
>YLK1_SCHPO (Q9P7H8) Hypothetical protein C1782.01 in chromosome I
Length = 1679
Score = 28.9 bits (63), Expect = 2.1
Identities = 21/81 (25%), Positives = 37/81 (44%), Gaps = 13/81 (16%)
Query: 41 SKGW-----AVNTRDFILFGTPVLEYVKELR-------KNVELVIDSVSECGFEIDCLKI 88
S+ W +VNT +L PV EY+ +L + ++ + +SV E F + L
Sbjct: 1078 SRSWRDRESSVNTLVSLLSNVPVTEYLNQLEDIWNMSFRTLDDIKESVREASFPLCKLLA 1137
Query: 89 INEVEGRNRLLHNVSLPASFC 109
+ ++ + HN S P+ C
Sbjct: 1138 RSVIQSLEKTSHNTS-PSGIC 1157
>SETB_MOUSE (O88974) Histone-lysine N-methyltransferase, H3 lysine-9
specific 4 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 4) (H3-K9-HMTase 4) (SET domain
bifurcated 1) (ERG-associated protein with SET domain)
(ESET)
Length = 1307
Score = 28.9 bits (63), Expect = 2.1
Identities = 15/43 (34%), Positives = 23/43 (52%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKEL 65
NR+ Q LQ LQ++ +KGW + D I G+ V Y ++
Sbjct: 811 NRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKI 853
>SETB_HUMAN (Q15047) Histone-lysine N-methyltransferase, H3 lysine-9
specific 4 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 4) (H3-K9-HMTase 4) (SET domain
bifurcated 1) (ERG-associated protein with SET domain)
(ESET)
Length = 1291
Score = 28.9 bits (63), Expect = 2.1
Identities = 15/43 (34%), Positives = 23/43 (52%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKEL 65
NR+ Q LQ LQ++ +KGW + D I G+ V Y ++
Sbjct: 794 NRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKI 836
>SU92_HUMAN (Q9H5I1) Histone-lysine N-methyltransferase, H3 lysine-9
specific 2 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of
variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
Length = 410
Score = 28.5 bits (62), Expect = 2.8
Identities = 18/44 (40%), Positives = 24/44 (53%), Gaps = 1/44 (2%)
Query: 23 NRISQKDLQYCLQVY-LKISKGWAVNTRDFILFGTPVLEYVKEL 65
NRI QK QY L ++ +GW V T I + V+EYV E+
Sbjct: 241 NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 284
>SEB2_HUMAN (Q96T68) Probable histone-lysine N-methyltransferase, H3
lysine-9 specific (EC 2.1.1.43) (Histone H3-K9
methyltransferase) (H3-K9-HMTase) (SET domain bifurcated
2) (Chronic lymphocytic leukemia deletion region gene 8
protein)
Length = 719
Score = 28.5 bits (62), Expect = 2.8
Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 23 NRISQKDLQYCLQVYLKISKGWAVNTRDFILFGTPVLEYVKEL--RKNVE 70
NR+ Q Q LQV+ KGW V D I GT V Y L R N E
Sbjct: 358 NRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTE 407
>GSHB_WIGBR (Q8D335) Glutathione synthetase (EC 6.3.2.3)
(Glutathione synthase) (GSH synthetase) (GSH-S) (GSHase)
Length = 316
Score = 27.7 bits (60), Expect = 4.8
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 13/110 (11%)
Query: 21 FDNRISQKDLQYCLQVYLKISK----GWAVNTRDFIL-----FGTPVLEYVKELRKNVEL 71
++ +IS +Y + + SK + D IL G + YVK+ NV +
Sbjct: 122 YNEKISTLSFKYSPKTLISCSKKAIYSFQEKFGDIILKPINKMGGDSVFYVKKNDPNVSV 181
Query: 72 VIDSVSECGFEIDCL--KIINEV-EGRNRLLHNVSLPASFCVERSVDDEE 118
+ID ++ G CL + I E+ G R++ P +C+ R +D+E
Sbjct: 182 IIDQLTNYGNSF-CLIQEYIKEILNGDRRIIMINGSPLPYCLVRIPNDKE 230
>DEOB_CLOAB (Q97HE6) Phosphopentomutase (EC 5.4.2.7)
(Phosphodeoxyribomutase)
Length = 390
Score = 27.7 bits (60), Expect = 4.8
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Query: 47 NTRDFIL--FGTPVLEYVKELRKNVELV--IDSVSECGFEIDCLKIINEVEGRNRLL 99
N RDF L F +LEY+KE + NV V I+ + + + I N ++G ++ L
Sbjct: 208 NRRDFALDPFNKTMLEYIKENKSNVMCVGKIEDIFNKKGVTEAVHIKNNMDGVDKTL 264
>SU92_MOUSE (Q9EQQ0) Histone-lysine N-methyltransferase, H3 lysine-9
specific 2 (EC 2.1.1.43) (Histone H3-K9
methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of
variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
Length = 477
Score = 27.3 bits (59), Expect = 6.2
Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 23 NRISQKDLQYCLQVYLKISK--GWAVNTRDFILFGTPVLEYVKEL 65
NRI QK QY L ++ K S GW V T I + V+EYV E+
Sbjct: 308 NRIVQKGTQYSLCIF-KTSNGCGWGVKTLVKIKRMSFVMEYVGEV 351
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.337 0.148 0.478
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,971,898
Number of Sequences: 164201
Number of extensions: 468808
Number of successful extensions: 2019
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2003
Number of HSP's gapped (non-prelim): 27
length of query: 121
length of database: 59,974,054
effective HSP length: 97
effective length of query: 24
effective length of database: 44,046,557
effective search space: 1057117368
effective search space used: 1057117368
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 58 (26.9 bits)
Lotus: description of TM0280a.7