BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0276.3
         (333 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PIP_ARATH (P93732) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   566  e-161
PIP_PLEBO (O83041) Probable proline iminopeptidase (EC 3.4.11.5)...   403  e-112
PIP_XYLFT (Q87DF8) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   366  e-101
PIP_XYLFA (Q9PD69) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   363  e-100
PIP_XANCI (P52279) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   361  1e-99
PIP_SERMA (O32449) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   360  2e-99
PIP_NEIGO (P42786) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   330  4e-90
PIP_NEIMB (Q9JZR6) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   328  9e-90
PIP_NEIMA (Q9JUV1) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...   327  3e-89
PIP_STRCO (Q9S2L4) Probable proline iminopeptidase (EC 3.4.11.5)...   230  3e-60
PIP_MYCGE (P47266) Putative proline iminopeptidase (EC 3.4.11.5)...   185  2e-46
PIP_MYCPN (P75092) Putative proline iminopeptidase (EC 3.4.11.5)...   184  2e-46
PIP_LACHE (P52278) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...    64  7e-10
PIP_BACCO (P46541) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...    63  1e-09
TPES_PSEPU (P07383) Tropinesterase (EC 3.1.1.10) (Atropinesteras...    59  2e-08
PIP_LACDE (P46544) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...    50  6e-06
DMPD_PSEUF (P19076) 2-hydroxymuconic semialdehyde hydrolase (EC ...    50  8e-06
PRXC_PSEFL (O31158) Non-heme chloroperoxidase (EC 1.11.1.10) (Ch...    49  2e-05
PIP_AERSO (P46547) Proline iminopeptidase (EC 3.4.11.5) (PIP) (P...    48  3e-05
HYEP_HUMAN (P07099) Epoxide hydrolase 1 (EC 3.3.2.3) (Microsomal...    47  7e-05

>PIP_ARATH (P93732) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 329

 Score =  567 bits (1460), Expect = e-161
 Identities = 264/316 (83%), Positives = 290/316 (91%), Gaps = 1/316 (0%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LY  IEPYS+G LKVSD+HT+YWEQSG P GHPVVFLHGGPGGGT+PSNRRFFDPEFY
Sbjct: 13  RTLYAPIEPYSSGNLKVSDVHTLYWEQSGKPDGHPVVFLHGGPGGGTAPSNRRFFDPEFY 72

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           RI+LFDQRGAGKSTPHACLE NTTWDL++DIEKLREHL+IPEW VFGGSWGSTLALAYSQ
Sbjct: 73  RIVLFDQRGAGKSTPHACLEENTTWDLVNDIEKLREHLKIPEWLVFGGSWGSTLALAYSQ 132

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERG-CFVDAYKK 190
           SHPDKVTG++LRGIFLLRKKEIDWFYEGGAAAI+PDAWE FRDLIPENERG   VDAY K
Sbjct: 133 SHPDKVTGLVLRGIFLLRKKEIDWFYEGGAAAIYPDAWEEFRDLIPENERGSSLVDAYHK 192

Query: 191 RLNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFF 250
           RLNSDD++ Q+AAARAWTKWEMMTA+L PN +NV+K +DD FSLAFARIENHYFVNKGFF
Sbjct: 193 RLNSDDLEIQYAAARAWTKWEMMTAYLRPNLENVQKAEDDKFSLAFARIENHYFVNKGFF 252

Query: 251 SSDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELG 310
            SDS+LLD VDKIRHI TTIVQGRYDVCCPMMSAWDLHKAWPEA+ ++V DAGHSANE G
Sbjct: 253 PSDSHLLDNVDKIRHIKTTIVQGRYDVCCPMMSAWDLHKAWPEAELKIVYDAGHSANEPG 312

Query: 311 IAAELVAANEKLKNII 326
           I+AELV ANEK+K ++
Sbjct: 313 ISAELVVANEKMKALM 328


>PIP_PLEBO (O83041) Probable proline iminopeptidase (EC 3.4.11.5)
           (PIP) (Prolyl aminopeptidase) (PAP)
          Length = 321

 Score =  403 bits (1035), Expect = e-112
 Identities = 194/310 (62%), Positives = 231/310 (73%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LYP I PY +G+L VS LHTIY+EQSGNP+G PVVFLHGGPGGGT P+ R++FDP  +
Sbjct: 2   RQLYPAIAPYQSGMLPVSALHTIYYEQSGNPNGKPVVFLHGGPGGGTIPTYRQYFDPSKW 61

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           RIILFDQRGAGKSTPHA L  NTTWDL+ DIEKLR HL I  W VFGGSWGSTL+LAYSQ
Sbjct: 62  RIILFDQRGAGKSTPHAELRENTTWDLVSDIEKLRSHLNIDRWFVFGGSWGSTLSLAYSQ 121

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKR 191
           +HPD+  G+ILRGIFLLR+KEI WFY+ GA+ IFPDAWE + + IP  ER   + AY +R
Sbjct: 122 THPDRCLGLILRGIFLLRRKEILWFYQDGASWIFPDAWEHYLEPIPPEERDDMISAYYRR 181

Query: 192 LNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFS 251
           L S D + +  AA+AW+ WE  T+ LI +     K  DD F+ AFARIE HYF+N+GFF 
Sbjct: 182 LTSKDAEIRSTAAKAWSVWEGTTSRLIVDPSLQSKFADDEFADAFARIECHYFINRGFFE 241

Query: 252 SDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGI 311
           +D  LL   D+I HI T IVQGRYDV CPM SAW LHKA PE++  VV DAGHS  E GI
Sbjct: 242 TDDQLLQNCDRIAHIPTVIVQGRYDVVCPMTSAWALHKALPESELIVVPDAGHSMMEAGI 301

Query: 312 AAELVAANEK 321
            + L+ A ++
Sbjct: 302 LSALIDATDR 311


>PIP_XYLFT (Q87DF8) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 313

 Score =  366 bits (940), Expect = e-101
 Identities = 172/309 (55%), Positives = 220/309 (70%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LYP + P+  G+L V D H +Y+EQ GNP G PVV LHGGPGGG +   RRF DP+ Y
Sbjct: 2   RTLYPEVTPFDHGMLCVDDSHRLYYEQCGNPHGKPVVILHGGPGGGCNDKMRRFHDPDKY 61

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           RI+LFDQRGAG+S PHA L +NTTWDL+ DIEKLR  L I  WQVFGGSWGSTLALAY+Q
Sbjct: 62  RIVLFDQRGAGRSMPHANLTNNTTWDLVADIEKLRVALGITRWQVFGGSWGSTLALAYAQ 121

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKR 191
           +HP++ T ++LRGIF+LR+ E++WFY+ GA+ +FPDAW+ +   IP  ER   + A+ +R
Sbjct: 122 THPEQTTELVLRGIFMLRRWELEWFYQEGASRLFPDAWDRYIAAIPPVERHDLISAFHRR 181

Query: 192 LNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFS 251
           L SDD  T+ AAA+AW+ WE  T+ L  ++D +   ++ HF+LAFARIENHYFVN GFF 
Sbjct: 182 LTSDDEATRLAAAQAWSLWEGATSCLYMDQDFIASHENPHFALAFARIENHYFVNGGFFE 241

Query: 252 SDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGI 311
            +  LL    +I +I   IV GRYDV CP+ +AWDLHKAWP+A  ++   AGHSA E   
Sbjct: 242 VEDQLLRDAQRIANIPGVIVHGRYDVVCPLQNAWDLHKAWPKASLKITPGAGHSAFEPQN 301

Query: 312 AAELVAANE 320
              LV A +
Sbjct: 302 IDALVCATD 310


>PIP_XYLFA (Q9PD69) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 313

 Score =  363 bits (933), Expect = e-100
 Identities = 170/309 (55%), Positives = 221/309 (71%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LYP + P+  G+L V D H +Y+EQ GNP G PVV LHGGPG G +   RRF DP+ Y
Sbjct: 2   RTLYPEVTPFEHGILCVDDNHRLYYEQCGNPHGKPVVILHGGPGSGCNDKMRRFHDPDKY 61

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           RI+LFDQRGAG+STPHA L +NTTWDL+ DIEKLR  L I  WQVFGGSWGSTLALAY+Q
Sbjct: 62  RIVLFDQRGAGRSTPHANLTNNTTWDLVADIEKLRVALGITRWQVFGGSWGSTLALAYAQ 121

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKR 191
           +HP++ T ++LRGIF+LR+ E++WFY+ GA+ +FPDAW+ +  +IP  ER   + A+ +R
Sbjct: 122 THPEQTTELVLRGIFMLRRWELEWFYQEGASHLFPDAWDRYIAVIPPVERHDLISAFHRR 181

Query: 192 LNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFS 251
           L S+D  T+ AAA+AW+ WE  T+ L  ++D +   ++ HF+LAFARIENHYFVN GFF 
Sbjct: 182 LTSEDEATRLAAAQAWSLWEGATSCLYMDQDFIASHENPHFALAFARIENHYFVNGGFFE 241

Query: 252 SDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGI 311
            ++ LL    +I +I   IV GRYDV CP+ +AWDLHK WP+A  ++   AGHSA E   
Sbjct: 242 VENQLLRDAQRIANIPGVIVHGRYDVVCPLQNAWDLHKVWPKASLKITPGAGHSAFEPQN 301

Query: 312 AAELVAANE 320
              LV A +
Sbjct: 302 IDALVCATD 310


>PIP_XANCI (P52279) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 313

 Score =  361 bits (927), Expect = 1e-99
 Identities = 176/309 (56%), Positives = 214/309 (68%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LYP I PY  G LKV D HT+Y+EQ GNP G PVV LHGGPGGG +   RRF DP  Y
Sbjct: 2   RTLYPEITPYQQGSLKVDDRHTLYFEQCGNPHGKPVVMLHGGPGGGCNDKMRRFHDPAKY 61

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           RI+LFDQRG+G+STPHA L  NTTWDL+ DIE+LR HL +  WQVFGGSWGSTLALAY+ 
Sbjct: 62  RIVLFDQRGSGRSTPHADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLALAYAA 121

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKR 191
                   ++LRGIFLLR+ E++WFY+ GA+ +FPDAWE + + IP  ER   + A+ +R
Sbjct: 122 DPSAAGHQLVLRGIFLLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERADLMSAFHRR 181

Query: 192 LNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFS 251
           L SDD  T+ AAA+AW+ WE  T+ L  +ED V   +D HF+LAFARIENHYFVN GFF 
Sbjct: 182 LTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHYFVNGGFFE 241

Query: 252 SDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGI 311
            +  LL    +I  I   IV GRYDV CP+ SAWDLHKAWP+A  ++   +GHSA E   
Sbjct: 242 VEDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKAQLQISPASGHSAFEPEN 301

Query: 312 AAELVAANE 320
              LV A +
Sbjct: 302 VDALVRATD 310


>PIP_SERMA (O32449) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 317

 Score =  360 bits (925), Expect = 2e-99
 Identities = 165/310 (53%), Positives = 220/310 (70%), Gaps = 1/310 (0%)

Query: 12  RNLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFY 71
           R LYP +  Y +G L   D H IYWE SGNP+G P VF+HGGPGGG SP +R+ FDPE Y
Sbjct: 5   RGLYPPLAAYDSGWLDTGDGHRIYWELSGNPNGKPAVFIHGGPGGGISPHHRQLFDPERY 64

Query: 72  RIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQ 131
           +++LFDQRG G+S PHA L++NTTW L+ DIE+LRE   + +W VFGGSWGSTLALAY+Q
Sbjct: 65  KVLLFDQRGCGRSRPHASLDNNTTWHLVADIERLREMAGVEQWLVFGGSWGSTLALAYAQ 124

Query: 132 SHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKR 191
           +HP++V+ ++LRGIF LRK+ + W+Y+ GA+  FP+ WE    ++ ++ER   + AY++R
Sbjct: 125 THPERVSEMVLRGIFTLRKQRLHWYYQDGASRFFPEKWERVLSILSDDERKDVIAAYRQR 184

Query: 192 LNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFS 251
           L S D Q Q  AA+ W+ WE  T  L+P+ ++   G+DD F+LAFARIENHYF + GF  
Sbjct: 185 LTSADPQVQLEAAKLWSVWEGETVTLLPSRESASFGEDD-FALAFARIENHYFTHLGFLE 243

Query: 252 SDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGI 311
           SD  LL  V  IRHI   IV GRYD+ C + +AWDL KAWPEA+  +V  AGHS +E GI
Sbjct: 244 SDDQLLRNVPLIRHIPAVIVHGRYDMACQVQNAWDLAKAWPEAELHIVEGAGHSYDEPGI 303

Query: 312 AAELVAANEK 321
             +L+ A ++
Sbjct: 304 LHQLMIATDR 313


>PIP_NEIGO (P42786) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 310

 Score =  330 bits (845), Expect = 4e-90
 Identities = 161/310 (51%), Positives = 211/310 (67%), Gaps = 6/310 (1%)

Query: 14  LYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRI 73
           +Y   +P+ +G L+VS++H IYWE+SGNP G PV+FLHGGPG G SP  R FF+P+ +RI
Sbjct: 1   MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRI 60

Query: 74  ILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSH 133
           ++ DQRG G+S P+AC E NTTWDL+ DIEK+RE L I +W VFGGSWGSTL+LAY+Q+H
Sbjct: 61  VIIDQRGCGRSHPYACAEDNTTWDLVADIEKVREMLGIGKWLVFGGSWGSTLSLAYAQTH 120

Query: 134 PDKVTGIILRGIFLLRKKEIDWFYE-GGAAAIFPDAWEPFRDLIPENERGCFVDAYKKRL 192
           P++V G++LRGIFL R  E  W  E GG + I+P+ W+ F   I EN R   ++AY   L
Sbjct: 121 PERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKFVAPIAENRRNRLIEAYHGLL 180

Query: 193 NSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSS 252
              D +   +AA+AW  WE       P   +    +D + SLA AR+ENHYFVN G+   
Sbjct: 181 FHQDEEVCLSAAKAWADWESYLIRFEPEGVD----EDAYASLAIARLENHYFVNGGWLQG 236

Query: 253 DSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGIA 312
           D  +L+ + KIRHI T IVQGRYD+C PM SAW+L KA+PEA+ RVV  AGH A +  +A
Sbjct: 237 DKAILNNIGKIRHIPTVIVQGRYDLCTPMQSAWELSKAFPEAELRVV-QAGHCAFDPPLA 295

Query: 313 AELVAANEKL 322
             LV A E +
Sbjct: 296 DALVQAVEDI 305


>PIP_NEIMB (Q9JZR6) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 310

 Score =  328 bits (842), Expect = 9e-90
 Identities = 161/310 (51%), Positives = 210/310 (66%), Gaps = 6/310 (1%)

Query: 14  LYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRI 73
           +Y   +P+ +G L+VS++H IYWE+SGNP G PV+FLHGGPG G SP  R FF+P+ +RI
Sbjct: 1   MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRI 60

Query: 74  ILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSH 133
           ++ DQRG G+S P+AC E NTTWDL+ DIEK+RE L I +W VFGGSWGSTL+LAY+Q+H
Sbjct: 61  VIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIGKWLVFGGSWGSTLSLAYAQTH 120

Query: 134 PDKVTGIILRGIFLLRKKEIDWFYE-GGAAAIFPDAWEPFRDLIPENERGCFVDAYKKRL 192
           P++V G++LRGIFL R  E  W  E GG + I+P+ W+ F   I EN R   ++AY   L
Sbjct: 121 PERVKGLVLRGIFLCRPSETVWLNEAGGVSRIYPEQWQKFVAPIAENRRNRLIEAYHGLL 180

Query: 193 NSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSS 252
              D +   +AA+AW  WE       P E +    +D + SLA AR+ENHYFVN G+   
Sbjct: 181 FHQDEEVCLSAAKAWADWESYLIRFEPEEVD----EDAYASLAIARLENHYFVNGGWLQG 236

Query: 253 DSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGIA 312
           D  +L+ + KIRHI T IVQGRYD+C PM SAW L KA+PEA+ RVV  AGH A +  + 
Sbjct: 237 DRAILNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVV-QAGHRAFDPPLV 295

Query: 313 AELVAANEKL 322
             LV A E +
Sbjct: 296 DALVQAVEDI 305


>PIP_NEIMA (Q9JUV1) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 310

 Score =  327 bits (838), Expect = 3e-89
 Identities = 160/310 (51%), Positives = 210/310 (67%), Gaps = 6/310 (1%)

Query: 14  LYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRI 73
           +Y   +P+ +G L+VS++H IYWE+SGNP G PV+FLHGGPG G SP  R FF+P+ +RI
Sbjct: 1   MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRI 60

Query: 74  ILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSH 133
           ++ DQRG G+S P+AC E NTTWDL+ DIEK+RE L I +W VFGGSWGSTL+LAY+Q+H
Sbjct: 61  VIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIGKWLVFGGSWGSTLSLAYAQTH 120

Query: 134 PDKVTGIILRGIFLLRKKEIDWFYE-GGAAAIFPDAWEPFRDLIPENERGCFVDAYKKRL 192
           P++V G++LRGIFL R  E  W  E GG + I+P+ W+ F   I EN R   ++AY   L
Sbjct: 121 PERVKGLVLRGIFLCRPSETVWLNEAGGVSRIYPEQWQKFVAPIAENRRNQLIEAYHGLL 180

Query: 193 NSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSS 252
              D +   +AA+AW  WE       P E +    +D + SLA AR+ENHYFVN G+   
Sbjct: 181 FHQDEEVCLSAAKAWADWESYLIRFEPEEVD----EDAYASLAIARLENHYFVNGGWLQG 236

Query: 253 DSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANELGIA 312
           D  +L+ + KI+HI T IVQGRYD+C PM SAW L KA+PEA+ RVV  AGH A +  + 
Sbjct: 237 DRAILNNIGKIQHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVV-QAGHRAFDPPLV 295

Query: 313 AELVAANEKL 322
             LV A E +
Sbjct: 296 DALVQAVEDI 305


>PIP_STRCO (Q9S2L4) Probable proline iminopeptidase (EC 3.4.11.5)
           (PIP) (Prolyl aminopeptidase) (PAP)
          Length = 323

 Score =  230 bits (587), Expect = 3e-60
 Identities = 134/318 (42%), Positives = 175/318 (54%), Gaps = 13/318 (4%)

Query: 13  NLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYR 72
           +LYP IEPY  G+L V D + +YWE  GNP G P V LHGGPG   SP  RR+FDP  YR
Sbjct: 2   SLYPEIEPYDHGMLDVGDGNHVYWETCGNPHGKPAVVLHGGPGSRASPGLRRYFDPAAYR 61

Query: 73  IILFDQRGAGKSTPHAC-----LEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLAL 127
           I+L DQRGAG+S P A      +  NTT  L+ D+E+LR HL I  W V+G SWGS L L
Sbjct: 62  IVLLDQRGAGRSLPRASAPDTDMSVNTTAHLMADLERLRVHLGIERWLVWGVSWGSVLGL 121

Query: 128 AYSQSHPDKVTGIILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPF-RDLIPENERGCFVD 186
            Y+Q+HP  VT ++L G+      E+      G   IFP+A E F  +L P+   G    
Sbjct: 122 RYAQTHPGVVTELVLTGVATGSNAEVA-LLTRGLGNIFPEAHERFLAELPPDARDGNLPA 180

Query: 187 AYKKRLNSDDIQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVN 246
           AY + L S D   +  AARAWT WE  T    P   +V +  D  F + FAR   HY+ N
Sbjct: 181 AYNRLLESPDPAVRERAARAWTDWETATIPAPPG--SVARYQDPDFRMGFARTVTHYWGN 238

Query: 247 KGFF---SSDSYLLDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAG 303
             F    + +  ++     ++ I  T+VQG  D    +   W LH AWP++D  +V +AG
Sbjct: 239 DHFLGDGNDEGVVIRDAHLLKGIPGTLVQGSLDFGNLLGIVWRLHHAWPDSDLVIVDEAG 298

Query: 304 HSANELGIAAELVAANEK 321
           H A   G  A L+AA +K
Sbjct: 299 HDAGTTGDEA-LLAATDK 315


>PIP_MYCGE (P47266) Putative proline iminopeptidase (EC 3.4.11.5)
           (PIP) (Prolyl aminopeptidase) (PAP)
          Length = 308

 Score =  185 bits (469), Expect = 2e-46
 Identities = 105/288 (36%), Positives = 149/288 (51%), Gaps = 6/288 (2%)

Query: 24  GLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRIILFDQRGAGK 83
           G L V D H +Y+   GNP+G PV+++HGGPG GT     ++FD E   IIL DQRG GK
Sbjct: 9   GYLNVGDNHQLYYWTQGNPNGKPVLYIHGGPGSGTDEGCLKYFDLETTWIILLDQRGCGK 68

Query: 84  STPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSHPDKVTGIILR 143
           S  +     N T  L+ D E LR+ L I  W +FGGSWGS LAL Y+  HP  V  I LR
Sbjct: 69  SKTNDIFYENNTDKLVSDFEILRQKLNIKNWTLFGGSWGSALALVYAIKHPQVVDKIFLR 128

Query: 144 GIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIP---ENERGCFVDAYKKRLNSDDIQTQ 200
            +FL R+K+      G     +P   + F D IP   +N     V+    +  + D  T+
Sbjct: 129 ALFLAREKDWSEALMGLGKMFYPYEHQRFMDSIPKAYQNSYEQIVNYCYDQFQNGDESTK 188

Query: 201 FAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSSDSYLLDGV 260
              A+AW  WE  +  L P         D       A +E HY VNK F   ++++LD +
Sbjct: 189 EKLAKAWVDWE--STLLSPINKIHSTATDFKLVEKLALLECHYAVNKSFL-DENFILDNI 245

Query: 261 DKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANE 308
             +++ +  +  GR+D+ CP+     L +A+PE    V  +AGHS ++
Sbjct: 246 SVLKNKSIYLAHGRFDLICPLYQPLALKQAFPELQLYVTNNAGHSGSD 293


>PIP_MYCPN (P75092) Putative proline iminopeptidase (EC 3.4.11.5)
           (PIP) (Prolyl aminopeptidase) (PAP)
          Length = 309

 Score =  184 bits (468), Expect = 2e-46
 Identities = 100/292 (34%), Positives = 159/292 (54%), Gaps = 5/292 (1%)

Query: 20  PYSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRIILFDQR 79
           P  +G LKV + H +Y+  +GNP G   +++HGGPG GT     ++FD +   +IL DQR
Sbjct: 5   PKQSGYLKVGNGHEVYFWTAGNPQGKSALYVHGGPGSGTDAGCLKYFDLDTTYVILLDQR 64

Query: 80  GAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSHPDKVTG 139
           G G+S     L HNTT DL+ D+E LR+HL++  W +FGGSWGSTLAL Y+ +HP  V  
Sbjct: 65  GCGQSKAVNPLLHNTTQDLVGDLEALRQHLKLERWTLFGGSWGSTLALVYAITHPQVVEQ 124

Query: 140 IILRGIFLLRKKEIDWFYEGGAAAIFPDAWEPFRDLIPE---NERGCFVDAYKKRLNSDD 196
           + LR +FL R+++      G     +P   +     IP+    +   F + + + L  +D
Sbjct: 125 VFLRALFLGREQDWAEMLLGLGKLFYPYEHQTLLKAIPQACRTDFTKFTNYFYEVLQGND 184

Query: 197 IQTQFAAARAWTKWEMMTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSSDSYL 256
              +   A AW KWE      I    + +K +D +F+   A +E HY  +  F    +++
Sbjct: 185 SALKTQLANAWVKWENTLLSPISYVKD-EKAEDANFTFKLALLECHYAKHHSFL-KPNFI 242

Query: 257 LDGVDKIRHINTTIVQGRYDVCCPMMSAWDLHKAWPEADFRVVADAGHSANE 308
           L+ V  ++     ++ GR+D+ CP+  A +L +A P  +  V  +AGHS ++
Sbjct: 243 LENVAVLKDKPVHLIHGRFDLVCPLSQALELKRALPTLNLYVTNNAGHSGSD 294


>PIP_LACHE (P52278) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 294

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 21/122 (17%)

Query: 32  HTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFD-------PEFYRIILFDQRGAGKS 84
           + I  E+S  P   P+V LHGGPG     S+  +F+        +  RII++DQ G G+S
Sbjct: 17  YRIVGERSEKP---PLVLLHGGPG-----SSHNYFEVLDELAQKDGRRIIMYDQLGCGES 68

Query: 85  T---PHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAY-SQSHPDKVTGI 140
           +    H  L    TW  + ++E LREHL + +  + G SWG  LA+ Y    HP+ +  +
Sbjct: 69  SIPDDHPELYTKETW--VKELEALREHLALRKMHLLGQSWGGMLAIIYMCDYHPEGIQSL 126

Query: 141 IL 142
           IL
Sbjct: 127 IL 128


>PIP_BACCO (P46541) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 288

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 39/124 (31%), Positives = 60/124 (47%), Gaps = 6/124 (4%)

Query: 21  YSTGLLKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRIILFDQRG 80
           Y+ G + V+     + +   N  G PV+ LHGGPG             +   +IL+DQ G
Sbjct: 2   YTEGFIDVTGGRVSFQKFDENGGGTPVIVLHGGPGSSCYSLLGLKALAKDRPVILYDQLG 61

Query: 81  AGKSTPHACLEHNTTWDL---IDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSHPDKV 137
            GKS         T W L   ++++ ++R+ L + E  + G SWG+TLA AY  + P  V
Sbjct: 62  CGKSDRPM---DTTLWRLDRFVEELAQIRQALNLDEVHILGHSWGTTLAAAYCLTKPSGV 118

Query: 138 TGII 141
             +I
Sbjct: 119 KSVI 122


>TPES_PSEPU (P07383) Tropinesterase (EC 3.1.1.10) (Atropinesterase)
           (Atropine acylhydrolase)
          Length = 272

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/142 (28%), Positives = 65/142 (45%), Gaps = 4/142 (2%)

Query: 26  LKVSDLHTIYWEQSGNPSGHPVVFLHGGPGGGTSPSNRRFFDPEFYRIILFDQRG-AGKS 84
           ++++D   + + + GNPSG PV+ LHG      + S+   F  +  R +  D RG  G S
Sbjct: 18  IQINDAIKMRYVEWGNPSGDPVLLLHGYTDTSRAFSSLAPFLSKDKRYLALDLRGHGGTS 77

Query: 85  TPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSHPDKVTGIILRG 144
            P  C   +   D  +D+    + + +    V G S GS  A   +  HPDKV+ ++L  
Sbjct: 78  IPKCCYYVS---DFAEDVSDFIDKMGLHNTTVIGHSMGSMTAGVLASIHPDKVSRLVLIS 134

Query: 145 IFLLRKKEIDWFYEGGAAAIFP 166
             L     ++W Y+      FP
Sbjct: 135 TALKTGPVLEWVYDTVLQKDFP 156


>PIP_LACDE (P46544) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 295

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 65/272 (23%), Positives = 107/272 (38%), Gaps = 40/272 (14%)

Query: 46  PVVFLHGGPGGGTSPSNRRFFD-------PEFYRIILFDQRGAGKST-PHACLEHN---T 94
           P++ LHGGPG     S+  +F+           ++I++DQ G G S+ P    E      
Sbjct: 29  PLLLLHGGPG-----SSHNYFEVLDQVAEKSGRQVIMYDQLGCGNSSIPDDQAETAYTAQ 83

Query: 95  TWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAY-SQSHPDKVTGIILRGIFLLRKKEI 153
           TW  + ++E +RE L + +  + G SWG  LAL Y     P+ V  +IL           
Sbjct: 84  TW--VKELENVREQLGLDQIHLLGQSWGGMLALIYLCDYQPEGVKSLILSSTL------- 134

Query: 154 DWFYEGGAAAIFPDAWEPFRDLIPENERGCFVDAYKKRLNSDDIQTQFAAARAWTKWEM- 212
                  +A ++          +P+ E+    +A +   N D +  Q A A    +  + 
Sbjct: 135 ------ASAKLWSQELHRLIKYLPKGEQAAIKEA-ETTGNYDSLAYQAANAHFMDQHAIK 187

Query: 213 MTAHLIPNEDNVKKGDDDHFSLAFARIENHYFVNKGFFSSDSYLLDGVDKIRHINTTIVQ 272
           +T  L       KKG    +   +   E     N   +     L D      H+   I  
Sbjct: 188 LTPDLPEPVLRKKKGGSLAYLTGWGPNEYTPIGNLHGYEYTDRLKD-----LHLPALITS 242

Query: 273 GRYDVCCPMMSAWDLHKAWPEADFRVVADAGH 304
           G  D+C P++ A  ++   P A + + A  GH
Sbjct: 243 GTDDLCTPLV-AKSMYDNLPNARWELFAGCGH 273


>DMPD_PSEUF (P19076) 2-hydroxymuconic semialdehyde hydrolase (EC
           3.1.1.-) (HMSH)
          Length = 283

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 6/106 (5%)

Query: 43  SGHPVVFLHGGPGGGTSPSNRRFFDPEFY---RIILFDQRGAGKSTPHACLEHNT-TWDL 98
           +G P++ +HG   G T+ +N R   PE     R+I  D  G G S   A  ++N   W  
Sbjct: 28  AGFPLMMIHGSGPGVTAWANWRLVMPELAKSRRVIAPDMLGFGYSERPADAQYNRDVW-- 85

Query: 99  IDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSHPDKVTGIILRG 144
           +D    + + LEI +  + G S+G  +ALA +  HP++V  ++L G
Sbjct: 86  VDHAVGVLDALEIEQADLVGNSFGGGIALALAIRHPERVRRLVLMG 131


>PRXC_PSEFL (O31158) Non-heme chloroperoxidase (EC 1.11.1.10)
           (Chloride peroxidase) (CPO-F) (Chloroperoxidase F)
          Length = 273

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/101 (34%), Positives = 50/101 (48%), Gaps = 5/101 (4%)

Query: 34  IYWEQSGNPSGHPVVFLHGGPGGGTS-PSNRRFFDPEFYRIILFDQRGAGKSTPHACLEH 92
           IY++  G  SG P+VF HG P    S  S   F   + YR+I  D+RG G+S+       
Sbjct: 11  IYYKDWG--SGQPIVFSHGWPLNADSWESQMIFLAAQGYRVIAHDRRGHGRSSQPWSGND 68

Query: 93  NTTWDLIDDIEKLREHLEIPEWQVFGGSWGSTLALAYSQSH 133
             T+   DD+ +L EHL++ +  +FG S G      Y   H
Sbjct: 69  MDTY--ADDLAQLIEHLDLRDAVLFGFSTGGGEVARYIGRH 107


>PIP_AERSO (P46547) Proline iminopeptidase (EC 3.4.11.5) (PIP)
           (Prolyl aminopeptidase) (PAP)
          Length = 424

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 21/118 (17%)

Query: 47  VVFLHGGPG-GGTSPSNRRFFDP---EFYRIILFDQRGAGKSTP-HA------------- 88
           +++L GGPG G   PS    +     + +R++L DQRG G STP HA             
Sbjct: 53  LLYLQGGPGFGAPRPSANGGWIKRALQEFRVLLLDQRGTGHSTPIHAELLAHLNPRQQAD 112

Query: 89  CLEHNTTWDLIDDIEKLREHLEIPE--WQVFGGSWGSTLALAYSQSHPDKVTGIILRG 144
            L H     ++ D E +RE L  P+  W + G S+G   +L Y    PD +  + L G
Sbjct: 113 YLSHFRADSIVRDAELIREQLS-PDHPWSLLGQSFGGFCSLTYLSLFPDSLHEVYLTG 169


>HYEP_HUMAN (P07099) Epoxide hydrolase 1 (EC 3.3.2.3) (Microsomal
           epoxide hydrolase) (Epoxide hydratase)
          Length = 455

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 41/149 (27%), Positives = 59/149 (39%), Gaps = 18/149 (12%)

Query: 13  NLYPHIEPYSTGLLKVSDLHTIYWEQSGNPSGH---PVVFLHGGPGGG----------TS 59
           N YPH +    GL    D+H I+ +    P+GH   P++ +HG PG            T 
Sbjct: 111 NRYPHFKTKIEGL----DIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTD 166

Query: 60  PSNRRFFDPEFYRIILFDQRGAGKSTPHACLEHNTTWDLIDDIEKLREHLEIPEWQVFGG 119
           P N    D   + +I     G G S   +    N+         KL   L   E+ + GG
Sbjct: 167 PKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSV-ATARIFYKLMLRLGFQEFYIQGG 225

Query: 120 SWGSTLALAYSQSHPDKVTGIILRGIFLL 148
            WGS +    +Q  P  V G+ L    +L
Sbjct: 226 DWGSLICTNMAQLVPSHVKGLHLNMALVL 254


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.320    0.138    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,989,551
Number of Sequences: 164201
Number of extensions: 2131300
Number of successful extensions: 4419
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 4333
Number of HSP's gapped (non-prelim): 86
length of query: 333
length of database: 59,974,054
effective HSP length: 111
effective length of query: 222
effective length of database: 41,747,743
effective search space: 9267998946
effective search space used: 9267998946
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)