BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0231b.3
(490 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PUR1_SOYBN (P52418) Amidophosphoribosyltransferase, chloroplast ... 773 0.0
PUR1_VIGAC (P52419) Amidophosphoribosyltransferase, chloroplast ... 716 0.0
PUR1_BACSU (P00497) Amidophosphoribosyltransferase precursor (EC... 398 e-110
PUR1_SYNY3 (Q55621) Amidophosphoribosyltransferase precursor (EC... 389 e-107
PUR1_STAAN (P99164) Amidophosphoribosyltransferase precursor (EC... 387 e-107
PUR1_STAAM (P65831) Amidophosphoribosyltransferase precursor (EC... 387 e-107
PUR1_STAAW (Q8NX91) Amidophosphoribosyltransferase precursor (EC... 386 e-107
PUR1_RHIET (P77935) Amidophosphoribosyltransferase precursor (EC... 385 e-106
PUR1_ARCFU (O29388) Probable amidophosphoribosyltransferase (EC ... 383 e-106
PUR1_STAEP (Q8CT30) Amidophosphoribosyltransferase precursor (EC... 381 e-105
PUR1_METTH (O26742) Amidophosphoribosyltransferase precursor (EC... 377 e-104
PUR1_SYNP7 (Q55038) Amidophosphoribosyltransferase precursor (EC... 376 e-104
PUR1_METJA (Q57657) Probable amidophosphoribosyltransferase (EC ... 374 e-103
PUR1_MYCTU (P65829) Amidophosphoribosyltransferase precursor (EC... 351 2e-96
PUR1_MYCBO (P65830) Amidophosphoribosyltransferase precursor (EC... 351 2e-96
PUR1_MYCLE (Q50028) Amidophosphoribosyltransferase precursor (EC... 345 2e-94
PUR1_PYRAB (Q9V253) Amidophosphoribosyltransferase precursor (EC... 333 8e-91
PUR1_PYRHO (O57979) Amidophosphoribosyltransferase precursor (EC... 332 2e-90
PUR1_HUMAN (Q06203) Amidophosphoribosyltransferase precursor (EC... 325 2e-88
PUR1_CHICK (P28173) Amidophosphoribosyltransferase precursor (EC... 325 2e-88
>PUR1_SOYBN (P52418) Amidophosphoribosyltransferase, chloroplast
precursor (EC 2.4.2.14) (Glutamine
phosphoribosylpyrophosphate amidotransferase) (ATASE)
(GPAT)
Length = 569
Score = 773 bits (1997), Expect = 0.0
Identities = 405/493 (82%), Positives = 432/493 (87%), Gaps = 10/493 (2%)
Query: 2 AASNFSTLSSSS-SSFSKSKPFTNTPCFPGNKTLHNPTSFPNPTTLSHAHKPPYPSPC-- 58
AASN STLSSSS S S S PF NTP LHN S PN +LSH P P C
Sbjct: 3 AASNLSTLSSSSLSKPSSSFPFRNTPTNNNASFLHNK-SLPNQNSLSHKLSSPLPLACNP 61
Query: 59 KNHNTTFPEPLCNDDEDQKPREECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVH 118
KN NT + DDEDQKPREECGVVGIYGDPEASRLC LALHALQHRGQEGAGIV VH
Sbjct: 62 KNQNTC----VFFDDEDQKPREECGVVGIYGDPEASRLCSLALHALQHRGQEGAGIVAVH 117
Query: 119 NNKIFQSVTGVGLVADVFTEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSV 178
+N + QSVTGVGLV+DVF ++KL +LPGT AIGHVRYSTAGQSMLKNVQPF+A YRF +V
Sbjct: 118 DNHL-QSVTGVGLVSDVFEQSKLSRLPGTSAIGHVRYSTAGQSMLKNVQPFLADYRFAAV 176
Query: 179 GVAHNGNLVNYRSLREKLEEN-GSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKG 237
VAHNGN VNYRSLR +LE N GSIFNT+SDTEVVLHLIATSK RPF+LRIVDACE L+G
Sbjct: 177 AVAHNGNFVNYRSLRARLEHNNGSIFNTTSDTEVVLHLIATSKHRPFLLRIVDACEHLQG 236
Query: 238 AYSFVFVTEDKLVAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVL 297
AYS VFVTEDKLVAVRDPFGFRPLVMG+R+NGAVV ASETCALDLIEA YEREVYPGEV+
Sbjct: 237 AYSLVFVTEDKLVAVRDPFGFRPLVMGRRTNGAVVLASETCALDLIEATYEREVYPGEVI 296
Query: 298 VVDKNGLQSLCLVSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECD 357
VVD G+QSLCLVSHPEPKQCIFEHIYF+LP+SVVFG+SVYESR+ FGEILA+ESPVECD
Sbjct: 297 VVDHTGIQSLCLVSHPEPKQCIFEHIYFALPNSVVFGRSVYESRKKFGEILASESPVECD 356
Query: 358 VVIAVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAV 417
VVIAVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRD GVKLKLSPV AV
Sbjct: 357 VVIAVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVHAV 416
Query: 418 LEGKRVVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELI 477
LEGKRVVVVDDSIVRGTTSSKIVRL+KEAGAKEVHMRIACPPI+ SCYYGVDTPSSEELI
Sbjct: 417 LEGKRVVVVDDSIVRGTTSSKIVRLLKEAGAKEVHMRIACPPIVASCYYGVDTPSSEELI 476
Query: 478 SNRMSVDEIREFI 490
SNRMSV+EIR+FI
Sbjct: 477 SNRMSVEEIRKFI 489
>PUR1_VIGAC (P52419) Amidophosphoribosyltransferase, chloroplast
precursor (EC 2.4.2.14) (Glutamine
phosphoribosylpyrophosphate amidotransferase) (ATASE)
(GPAT) (Fragment)
Length = 485
Score = 716 bits (1847), Expect = 0.0
Identities = 360/418 (86%), Positives = 386/418 (92%), Gaps = 2/418 (0%)
Query: 73 DEDQKPREECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLV 132
++D+KPREECGVVGIYGDPEASRLC LALHALQHRGQEGAGIV VH+N +F V GVGLV
Sbjct: 10 NDDEKPREECGVVGIYGDPEASRLCSLALHALQHRGQEGAGIVAVHDN-LFHQVNGVGLV 68
Query: 133 ADVFTEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSL 192
+DVF EAKL +LPG+ AIGHVRYSTAG S L NVQPFVAGYRFGSV VAHNGN VNYRSL
Sbjct: 69 SDVFNEAKLSELPGSCAIGHVRYSTAGHSKLVNVQPFVAGYRFGSVAVAHNGNFVNYRSL 128
Query: 193 REKLEENGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAV 252
R KLE+NGSIFNT+SDTEVVLHLIATSK RPF+LR+VDACE LKGAYS VF+TEDKLVAV
Sbjct: 129 RAKLEDNGSIFNTTSDTEVVLHLIATSKHRPFLLRVVDACENLKGAYSLVFLTEDKLVAV 188
Query: 253 RDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSH 312
RD FGFRPLVMG+R NGAVVFASETCALDLI+A YEREV PGEV+VVD G+QSLCLV+H
Sbjct: 189 RD-FGFRPLVMGRRKNGAVVFASETCALDLIDATYEREVNPGEVVVVDHTGIQSLCLVTH 247
Query: 313 PEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALG 372
EPKQCIFEHIYF+LP+SVVFG+SVYESRR FGEILATESPVECDVVIAVPDSGVVAALG
Sbjct: 248 QEPKQCIFEHIYFALPNSVVFGRSVYESRRKFGEILATESPVECDVVIAVPDSGVVAALG 307
Query: 373 YAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVR 432
YAAKAGVPFQQGLIRSH+VGRTFIEPSQKIRD GVKLKL PV+ VLEGKRVVVVDDSIVR
Sbjct: 308 YAAKAGVPFQQGLIRSHHVGRTFIEPSQKIRDFGVKLKLFPVRGVLEGKRVVVVDDSIVR 367
Query: 433 GTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
GTTSSKIVRLIKEAGAKEVHMRIACPPI+ SCYYGVDTPS EELISNRM V+EIR+FI
Sbjct: 368 GTTSSKIVRLIKEAGAKEVHMRIACPPIVASCYYGVDTPSKEELISNRMDVEEIRKFI 425
>PUR1_BACSU (P00497) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 476
Score = 398 bits (1023), Expect = e-110
Identities = 209/412 (50%), Positives = 285/412 (68%), Gaps = 3/412 (0%)
Query: 80 EECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
EECGV GI+G EA ++ Y LH+LQHRGQEGAGIV K+ + G GL+ +VF
Sbjct: 10 EECGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKL-TAHKGQGLITEVFQNG 68
Query: 140 KLDQLPGTLAIGHVRYSTAGQSMLKNVQPFV-AGYRFGSVGVAHNGNLVNYRSLREKLEE 198
+L ++ G AIGHVRY+TAG +NVQP + GS+ +AHNGNLVN L+++LE
Sbjct: 69 ELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLEN 128
Query: 199 NGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFGF 258
GSIF TSSDTEV+ HLI S +I ++ LKGAY+F+ +TE +++ DP G
Sbjct: 129 QGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGL 188
Query: 259 RPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPEPKQC 318
RPL +G + VV ASETCA D++ A Y REV PGE+L+++ G++S + C
Sbjct: 189 RPLSIGMMGDAYVV-ASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSIC 247
Query: 319 IFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYAAKAG 378
E+IYFS P S + G +V+ +R+ G++LA ES VE DVV VPDS + AA+GYA G
Sbjct: 248 SMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATG 307
Query: 379 VPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSK 438
+P++ GLI++ YVGRTFI+PSQ +R+ GV++KLS V+ V+EGKRVV+VDDSIVRGTTS +
Sbjct: 308 IPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRR 367
Query: 439 IVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
IV +++EAGA EVH++I+ PPI C+YG+DT + EELI++ SV EIR+ I
Sbjct: 368 IVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVGEIRQEI 419
>PUR1_SYNY3 (Q55621) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 495
Score = 389 bits (998), Expect = e-107
Identities = 211/430 (49%), Positives = 286/430 (66%), Gaps = 8/430 (1%)
Query: 67 EPLCNDDEDQKPREECGVVGIYGDPEA-SRLCYLALHALQHRGQEGAGIVTVHNNKIFQS 125
+PL D KP E CGV GIY EA ++L Y L+ALQHRGQE AGI T +
Sbjct: 15 QPLSGHHAD-KPEEACGVFGIYAPEEAVAKLTYFGLYALQHRGQESAGIATFAGTTV-HC 72
Query: 126 VTGVGLVADVFTEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGN 185
+GLV+ VF E+KL+++ GTLA+GH RYST G S N QP V R G + +AHNGN
Sbjct: 73 HKDMGLVSQVFQESKLNEMVGTLAVGHTRYSTTGSSHRVNAQPAVLPTRLGPLALAHNGN 132
Query: 186 LVNYRSLREKLEENG-SIFNTSSDTEVVLHLIATS--KQRPFILRIVDACEKLKGAYSFV 242
LVN LRE L E G F T++D+E++ IA K + ++ + A GAYS V
Sbjct: 133 LVNTNQLREALAERGCEDFVTTTDSEMIAVAIANEVDKGKDWVEGTIAALTLCAGAYSLV 192
Query: 243 FVTEDKLVAVRDPFGFRPLVMG--KRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVD 300
T + ++ VRDP G RPLV+G + V ASETCALD+I A Y R V GE++ +
Sbjct: 193 IGTPEGIIGVRDPHGIRPLVIGVLEEETPRYVLASETCALDIIGATYVRTVEAGELVHIT 252
Query: 301 KNGLQSLCLVSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVI 360
++GL S L + K C+FE IYFS P SVV +S+Y R G+ LA ESPV+ D+V+
Sbjct: 253 ESGLVSHRLAESADRKLCVFEMIYFSRPDSVVNDESLYTYRMRIGKHLAKESPVDADLVM 312
Query: 361 AVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEG 420
VPDSG+ AA+G++ +G+P+ +GLI++ YVGRTFI+P+Q +R+ G+++KL+P+K VL G
Sbjct: 313 GVPDSGIPAAIGFSQASGIPYAEGLIKNRYVGRTFIQPTQHMREHGIRMKLNPLKDVLAG 372
Query: 421 KRVVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNR 480
KR+++VDDSIVRGTTS KIVR ++EAGA EVHMRI+ PP+ C+YG+DT S ++LI+ R
Sbjct: 373 KRIIIVDDSIVRGTTSRKIVRALREAGATEVHMRISSPPVTHPCFYGIDTDSQDQLIAAR 432
Query: 481 MSVDEIREFI 490
++V EI E I
Sbjct: 433 LTVAEIAEQI 442
>PUR1_STAAN (P99164) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 494
Score = 387 bits (993), Expect = e-107
Identities = 186/412 (45%), Positives = 289/412 (70%), Gaps = 2/412 (0%)
Query: 80 EECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
EECGV GI+ PEA++L Y+ LH+LQHRGQEGAGIV N++ + G+GL+ + +
Sbjct: 9 EECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNEL-KGERGLGLLTEAINDD 67
Query: 140 KLDQLPGTL-AIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEE 198
++++L G AIGHVRY+T+G ++N+QPF+ + SVG+ HNGNL+N +SLR+ LE+
Sbjct: 68 QMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEK 127
Query: 199 NGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFGF 258
G+IF++SSDTEV++HLI SK F + ++ K+KG ++F +T+D L DP
Sbjct: 128 QGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAI 187
Query: 259 RPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPEPKQC 318
RPLV+GK +G + ASETCA+D++ AE+ ++++ GE +V++ G+ H
Sbjct: 188 RPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAIS 247
Query: 319 IFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYAAKAG 378
E+IYF+ P S + GK+V+ R+ G+ LA ESPV D+VI VP+S + AA GYA + G
Sbjct: 248 AMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIG 307
Query: 379 VPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSK 438
+P++ GL+++ YV RTFI+P+Q++R+ GV++KLS VK +++GK +++VDDSIVRGTT +
Sbjct: 308 LPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRR 367
Query: 439 IVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
IV+++K++GA +VH+RIA P + +YG+D ++ ELIS S +EI+++I
Sbjct: 368 IVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYI 419
>PUR1_STAAM (P65831) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 494
Score = 387 bits (993), Expect = e-107
Identities = 186/412 (45%), Positives = 289/412 (70%), Gaps = 2/412 (0%)
Query: 80 EECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
EECGV GI+ PEA++L Y+ LH+LQHRGQEGAGIV N++ + G+GL+ + +
Sbjct: 9 EECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNEL-KGERGLGLLTEAINDD 67
Query: 140 KLDQLPGTL-AIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEE 198
++++L G AIGHVRY+T+G ++N+QPF+ + SVG+ HNGNL+N +SLR+ LE+
Sbjct: 68 QMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEK 127
Query: 199 NGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFGF 258
G+IF++SSDTEV++HLI SK F + ++ K+KG ++F +T+D L DP
Sbjct: 128 QGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAI 187
Query: 259 RPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPEPKQC 318
RPLV+GK +G + ASETCA+D++ AE+ ++++ GE +V++ G+ H
Sbjct: 188 RPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAIS 247
Query: 319 IFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYAAKAG 378
E+IYF+ P S + GK+V+ R+ G+ LA ESPV D+VI VP+S + AA GYA + G
Sbjct: 248 AMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIG 307
Query: 379 VPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSK 438
+P++ GL+++ YV RTFI+P+Q++R+ GV++KLS VK +++GK +++VDDSIVRGTT +
Sbjct: 308 LPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRR 367
Query: 439 IVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
IV+++K++GA +VH+RIA P + +YG+D ++ ELIS S +EI+++I
Sbjct: 368 IVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYI 419
>PUR1_STAAW (Q8NX91) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 494
Score = 386 bits (992), Expect = e-107
Identities = 186/412 (45%), Positives = 289/412 (70%), Gaps = 2/412 (0%)
Query: 80 EECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
EECGV GI+ PEA++L Y+ LH+LQHRGQEGAGIV N++ + G+GL+ + +
Sbjct: 9 EECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNEL-KGERGLGLLTEAIKDD 67
Query: 140 KLDQLPGTL-AIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEE 198
++++L G AIGHVRY+T+G ++N+QPF+ + SVG+ HNGNL+N +SLR+ LE+
Sbjct: 68 QMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEK 127
Query: 199 NGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFGF 258
G+IF++SSDTEV++HLI SK F + ++ K+KG ++F +T+D L DP
Sbjct: 128 QGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAI 187
Query: 259 RPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPEPKQC 318
RPLV+GK +G + ASETCA+D++ AE+ ++++ GE +V++ G+ H
Sbjct: 188 RPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAIS 247
Query: 319 IFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYAAKAG 378
E+IYF+ P S + GK+V+ R+ G+ LA ESPV D+VI VP+S + AA GYA + G
Sbjct: 248 AMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIG 307
Query: 379 VPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSK 438
+P++ GL+++ YV RTFI+P+Q++R+ GV++KLS VK +++GK +++VDDSIVRGTT +
Sbjct: 308 LPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRR 367
Query: 439 IVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
IV+++K++GA +VH+RIA P + +YG+D ++ ELIS S +EI+++I
Sbjct: 368 IVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYI 419
>PUR1_RHIET (P77935) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 498
Score = 385 bits (989), Expect = e-106
Identities = 213/442 (48%), Positives = 301/442 (67%), Gaps = 17/442 (3%)
Query: 60 NHNTTFP--EPLCNDDEDQKPREECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTV 117
N + +FP +PL D EECGV GI G P+A+ L L LHALQHRGQE AGIV+
Sbjct: 2 NQSHSFPTDDPLDGDTL----HEECGVFGILGHPDAAALTALGLHALQHRGQEAAGIVSF 57
Query: 118 HNNKIFQSVTGVGLVADVFTEAK-LDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFG 176
+ +Q +GLV D +T L +LPG+++IGH RYST G+ ++NVQP A G
Sbjct: 58 DGKRFYQE-RHMGLVGDHYTNPMTLARLPGSISIGHTRYSTTGEVAMRNVQPLFAELEEG 116
Query: 177 SVGVAHNGNLVNYRSLREKLEENGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLK 236
+ +AHNGN N +LR ++ G+I ++SDTEVVLHLIA S+ R +DA +++
Sbjct: 117 GIAIAHNGNFTNGLTLRRQIIATGAICQSTSDTEVVLHLIARSRHASTSDRFIDAIRQME 176
Query: 237 GAYSFVFVTEDKLVAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEV 296
G YS + +T KL+A P G RPLVMG+ +G +F SETCALD+I A++ R+V GEV
Sbjct: 177 GGYSMLAMTRTKLIAASHPTGIRPLVMGEL-DGKPIFCSETCALDIIGAKFIRDVENGEV 235
Query: 297 LVVDKNGLQSLCL----VSHPEPKQ-CIFEHIYFSLPSSVVFGKSVYESRRLFGEILATE 351
++ + S+ + S P+P++ C+FE++YF+ P SVV G++VY +R+ G LA E
Sbjct: 236 IICEIQPDGSISIDARKPSKPQPERLCLFEYVYFARPDSVVGGRNVYTTRKNMGMNLAKE 295
Query: 352 SPVECDVVIAVPDSGVVAALGYAAKAGVPFQQ--GLIRSHYVGRTFIEPSQKIRDLGVKL 409
SPV+ DVV+ VPD G AA GYA ++G+PF+ G+IR+HYVGRTFIEP+Q+IR GVKL
Sbjct: 296 SPVDADVVVPVPDGGTSAAGGYAQESGIPFEYEYGIIRNHYVGRTFIEPTQQIRAFGVKL 355
Query: 410 KLSPVKAVLEGKRVVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVD 469
K S +A++EGKRVV+VDDSIVRGTTS KIV++I+EAGA+EVH+R+A P I +YG
Sbjct: 356 KHSANRAMIEGKRVVLVDDSIVRGTTSLKIVQMIREAGAREVHIRVASPMIFFRDFYGSI 415
Query: 470 TPSSEELISNRMS-VDEIREFI 490
P+ ++L++N+ + V+ + ++I
Sbjct: 416 RPTPDKLLANQYADVEAMAKYI 437
>PUR1_ARCFU (O29388) Probable amidophosphoribosyltransferase (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 456
Score = 383 bits (983), Expect = e-106
Identities = 201/414 (48%), Positives = 281/414 (67%), Gaps = 17/414 (4%)
Query: 82 CGVVGIYG-DPE-ASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
CGVVGIY D E A RL Y +L +LQHRGQE AGI + N+ + G+GLV +VF +
Sbjct: 1 CGVVGIYHPDGELAPRLAYYSLFSLQHRGQESAGIASFDNH--IRQKRGMGLVTEVFNDE 58
Query: 140 KLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEEN 199
+ L G IGHVRYST G+S L+N QPFV + G + VAHNGNLVNY LR +LE
Sbjct: 59 DFELLAGKSVIGHVRYSTTGRSRLENAQPFVVKSKAGYIAVAHNGNLVNYSQLRNELENE 118
Query: 200 GSIFNTSSDTEVVLHLIATSKQRPFILR---IVDACEKLK----GAYSFVFVTEDKLVAV 252
G +F T SDTEV+ L++ F++ I++A E+L G+Y+ + +D ++
Sbjct: 119 GRVFTTDSDTEVISQLLSK-----FLIEEGDIINALERLNESLVGSYTMTMLVDDAVIGY 173
Query: 253 RDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSH 312
RDP GF+PL +G+ +G V+ SE+CA+D + E+ R+V PG+ ++ L+ + +
Sbjct: 174 RDPLGFKPLCVGRIDDGYVI-CSESCAIDALGGEFIRDVQPGKAAIIKDGELEFVKIAKS 232
Query: 313 PEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALG 372
CIFE+IYF+ P S++ G SVY++R G++LA ESPVE D V AVPDSG+ AA+G
Sbjct: 233 ERRAVCIFEYIYFARPDSIIDGISVYKARSEMGKVLARESPVEADFVSAVPDSGITAAIG 292
Query: 373 YAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVR 432
YA ++G+P+ +GLI++ YVGRTFI P Q +R+ V+LK++ V+ + G+RVV+VDDSIVR
Sbjct: 293 YAQESGLPYFEGLIKNRYVGRTFIMPVQSLRETSVRLKVNVVRENVRGRRVVLVDDSIVR 352
Query: 433 GTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEI 486
GTTS +IV++IK+AGAKEVHMRI PPII CY+G+D S EELI+ +V+EI
Sbjct: 353 GTTSRRIVQMIKDAGAKEVHMRIGSPPIIAPCYFGIDMKSREELIAASHTVEEI 406
>PUR1_STAEP (Q8CT30) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 494
Score = 381 bits (979), Expect = e-105
Identities = 186/412 (45%), Positives = 284/412 (68%), Gaps = 2/412 (0%)
Query: 80 EECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
EECGV GI+ PEA++L Y+ LH+LQHRGQEGAGIV V N++ + G+GL+ + +
Sbjct: 9 EECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIV-VSNHETLKGERGLGLLTEAIKDE 67
Query: 140 KLDQLPG-TLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEE 198
+ + G AIGHVRY+T+G ++N+QPF+ + SVG+ HNGNL+N +SLR+ LEE
Sbjct: 68 HMSNIKGYPHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEE 127
Query: 199 NGSIFNTSSDTEVVLHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFGF 258
G+IF++SSDTEV++HLI SK F + ++ +KG ++F +T+D L V DP
Sbjct: 128 QGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRLIKGGFTFAILTKDALYGVVDPNAI 187
Query: 259 RPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPEPKQC 318
RPLV+GK NGA + ASETCA+D++ AE+ ++++ GE +V+ G++
Sbjct: 188 RPLVVGKMENGAYILASETCAIDVLGAEFIQDIHAGEYVVITDEGIEVKTYTRQTTTAIS 247
Query: 319 IFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYAAKAG 378
E+IYF+ P S + GK+V+ R+ G+ LA E+P + D+VI VP+S + AA GYA + G
Sbjct: 248 AMEYIYFARPDSTIAGKNVHAVRKASGKRLAQENPAKADMVIGVPNSSLSAASGYAEEIG 307
Query: 379 VPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSK 438
+P++ GL+++ YV RTFI+P+Q++R+ GV++KLS VK +++GK +V+VDDSIVRGTT +
Sbjct: 308 LPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKDIVLVDDSIVRGTTIKR 367
Query: 439 IVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
IV+++K++GA +H+RIA P + +YG+D ++ ELIS S +EI+ I
Sbjct: 368 IVKMLKDSGANRIHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKNHI 419
>PUR1_METTH (O26742) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 474
Score = 377 bits (969), Expect = e-104
Identities = 189/421 (44%), Positives = 284/421 (66%), Gaps = 7/421 (1%)
Query: 75 DQKPREECGVVGIYGDPEASRLC---YLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGL 131
+ + R++CG+VGIY + + + Y AL+ALQHRGQE AGI T + N I G+GL
Sbjct: 4 ESEVRDKCGIVGIYSQDKKTGVASQIYYALYALQHRGQESAGISTFNGNDILTH-RGMGL 62
Query: 132 VADVFTEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRS 191
V DVF KL++L G + IGHVRYST G+S ++N QPF + ++ G + +AHNG+++N
Sbjct: 63 VCDVFNPEKLEELKGNVGIGHVRYSTTGESRIENSQPFWSEFQGGKIAIAHNGDIINSME 122
Query: 192 LREKLEENGSIFNTSSDTEVVLHLIATS-KQRP-FILRIVDACEKLKGAYSFVFVTEDKL 249
LRE+LEE G F +++D+EV+ HL++ ++P I I E+L G+YS V + L
Sbjct: 123 LREELEEEGHNFVSTTDSEVICHLLSREYDEKPNMIYSIKRVSEQLVGSYSLVVLLNQDL 182
Query: 250 VAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCL 309
VRDP G +PL ++ + +V ASET A D+I AE+ R+V PGE+L +++ +
Sbjct: 183 YVVRDPVGIKPLAFARKGSTQIV-ASETVAFDVIGAEHVRDVQPGEILHLNRGKSYWVAN 241
Query: 310 VSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVA 369
+ C+FE++YF+ P SV+ G++VY R GE L E P DVV+ VPDS + A
Sbjct: 242 APNTRRAHCMFEYVYFARPDSVIDGRNVYRVRLNIGEALYREHPANADVVVPVPDSSIPA 301
Query: 370 ALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDS 429
A+GY+ +G+P+ +GLI++ YVGRTFI P+Q+ R+ VKLK++P+++ LEGKR+V++DDS
Sbjct: 302 AIGYSRASGIPYGEGLIKNRYVGRTFIMPTQEERETAVKLKMNPIRSELEGKRIVLIDDS 361
Query: 430 IVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREF 489
IVRGTTS ++ +I++AGA+E+H+RI CPPI CYYG+ + +ELI++ +V+EIR
Sbjct: 362 IVRGTTSRALIDIIRDAGAEEIHLRIGCPPIKSPCYYGIAMATKKELIASTRNVEEIRRI 421
Query: 490 I 490
I
Sbjct: 422 I 422
>PUR1_SYNP7 (Q55038) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 493
Score = 376 bits (966), Expect = e-104
Identities = 191/424 (45%), Positives = 277/424 (65%), Gaps = 7/424 (1%)
Query: 73 DEDQKPREECGVVGIYGD-PEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGL 131
+ +P E CGV +Y E +R+ Y L+ALQHRGQE AGI +++ +GL
Sbjct: 18 ERPDRPEEACGVFALYAPGEEVARMAYFGLYALQHRGQESAGIAVFEGDRVMLH-KDMGL 76
Query: 132 VADVFTEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRS 191
V+ VF L QL G+LA+GH RYST G S + N QP + R G V +AHNGNLVN
Sbjct: 77 VSQVFDPEILQQLQGSLAVGHTRYSTTGSSRIANAQPALLETRLGPVALAHNGNLVNTVE 136
Query: 192 LREKLEENGSIFNTSSDTEVVLHLI--ATSKQRPFILRIVDACEKLKGAYSFVFVTEDKL 249
LR++L T++D+E++ I A ++ + + I AC + +GA+S T + L
Sbjct: 137 LRQELLAKNHELTTTTDSELIAFAIMEAVAEGQDWRGAIESACRRSQGAFSLTIGTPEAL 196
Query: 250 VAVRDPFGFRPLVMGK-RSNGAV--VFASETCALDLIEAEYEREVYPGEVLVVDKNGLQS 306
RDP G RPLV+G SNG V +SETC LD+I A+Y R++ PGE++ + GL+S
Sbjct: 197 YGTRDPNGIRPLVLGTLESNGQTRYVLSSETCGLDIIGADYVRDIAPGEMVRITDAGLES 256
Query: 307 LCLVSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSG 366
P+PK C+FE IYF+ P S+ G+S+Y RR G+ LA E+P + D+V+ VPDSG
Sbjct: 257 WTWAEAPQPKLCVFEMIYFARPDSLFHGESLYSYRRRIGQRLAKEAPADVDLVLGVPDSG 316
Query: 367 VVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVV 426
+ AA+G++ G+P+ +GLI++ YVGRTFI+P+Q +R+ G+++KL+P+K VL GKR+ ++
Sbjct: 317 IPAAIGFSEALGIPYAEGLIKNRYVGRTFIQPTQSMRETGIRMKLNPLKDVLAGKRIAII 376
Query: 427 DDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEI 486
DDSIVRGTTS K+V+ +++AGA EVHMRI+ PP+ C+YG+DT + ++LI+ SV EI
Sbjct: 377 DDSIVRGTTSRKLVKALRDAGATEVHMRISSPPVTHPCFYGIDTDTQDQLIAATRSVSEI 436
Query: 487 REFI 490
E I
Sbjct: 437 TEQI 440
>PUR1_METJA (Q57657) Probable amidophosphoribosyltransferase (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 470
Score = 374 bits (961), Expect = e-103
Identities = 202/428 (47%), Positives = 277/428 (64%), Gaps = 21/428 (4%)
Query: 82 CGVVGIYGDPE--ASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTEA 139
CG+ GIY ++ Y L ALQHRGQEGAGI T + K +GLV DVF
Sbjct: 1 CGIFGIYSYERLNVAKKIYYGLFALQHRGQEGAGIAT-SDGKNIHYYKNIGLVTDVFKNE 59
Query: 140 KLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEEN 199
L L G + IGHVRYST G ++N QPFV FG++ +AHNG+LVN LR +LE
Sbjct: 60 TLQNLFGYIGIGHVRYSTTGGKAVENCQPFVVKSSFGNIAIAHNGDLVNSDELRRELEMK 119
Query: 200 GSIFNTSSDTEVVLHLIATS--KQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRDPFG 257
G IF +S+D+EV+ L+ K I I + +KL GAYS + + D L+AVRDP+G
Sbjct: 120 GHIFTSSTDSEVIAQLLVRELLKTSDKIEAIKNTLKKLVGAYSLLIMFNDSLIAVRDPWG 179
Query: 258 FRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCL---VSHPE 314
F+PL +G R + +SE CAL ++AE+ +++ PGE++ + + S L VS
Sbjct: 180 FKPLCIG-RDESNIYISSEDCALTTLDAEFVKDIEPGEIIEIKDGEIISHKLDYGVSEYN 238
Query: 315 PKQ------------CIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAV 362
P C+FE++YF+ P S + G SVY+ R+ G+ILA E PV+ DVV +
Sbjct: 239 PVNVDVPCIYRGAATCMFEYVYFARPDSTIDGISVYKVRKRIGKILAKEHPVDADVVSPI 298
Query: 363 PDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKR 422
PDSGV ALG++ ++G+P+ +GLI++ YVGRTFI PSQ R+L V+LKLSPVK+VLEGKR
Sbjct: 299 PDSGVTFALGFSEESGIPYYEGLIKNRYVGRTFILPSQNERELAVRLKLSPVKSVLEGKR 358
Query: 423 VVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMS 482
VV+VDDSIVRGTTS +IV ++++AGAKEVH+RI CP II CYYG+D + +ELI++ +
Sbjct: 359 VVLVDDSIVRGTTSRRIVNMVRKAGAKEVHLRIGCPKIISPCYYGIDMATKKELIASNKT 418
Query: 483 VDEIREFI 490
+EI + I
Sbjct: 419 EEEIGKAI 426
>PUR1_MYCTU (P65829) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 527
Score = 351 bits (901), Expect = 2e-96
Identities = 189/422 (44%), Positives = 277/422 (64%), Gaps = 12/422 (2%)
Query: 78 PREECGVVGIYGDPE-ASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVF 136
PREECGV G++ E ++L Y L+ALQHRGQE AGI +++ +GLV+ VF
Sbjct: 31 PREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLV-FKDLGLVSQVF 89
Query: 137 TEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGS-VGVAHNGNLVNYRSLREK 195
E L + G +AIGH RYST G + +N QP G+ V + HNGNLVN +L +
Sbjct: 90 DEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAAR 149
Query: 196 LEENGSIFN-----TSSDTEVVLHLIATSKQRPFILRI-VDACEKLKGAYSFVFVTEDKL 249
+ G I ++D++++ L+A + + +D ++GA+ F+ E+ L
Sbjct: 150 ARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTL 209
Query: 250 VAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCL 309
A RDP+G RPL +G+ G VV ASET ALD++ A + R++ PGE+L +D +G++S
Sbjct: 210 YACRDPYGVRPLSLGRLDRGWVV-ASETAALDIVGASFVRDIEPGELLAIDADGVRSTRF 268
Query: 310 VSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVA 369
++P PK C+FE++Y + P S + G+SV+ +R G LA E PVE D+VI VP+SG A
Sbjct: 269 -ANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPA 327
Query: 370 ALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDS 429
A+GYA ++GVP+ QGL+++ YVGRTFI+PSQ IR LG++LKL+P+K V+ GKR++VVDDS
Sbjct: 328 AVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDS 387
Query: 430 IVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRM-SVDEIRE 488
IVRG T +VR+++EAGA E+H+RIA PP+ C+YG+D PS ELI+N + + DE+ E
Sbjct: 388 IVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLE 447
Query: 489 FI 490
+
Sbjct: 448 AV 449
>PUR1_MYCBO (P65830) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 527
Score = 351 bits (901), Expect = 2e-96
Identities = 189/422 (44%), Positives = 277/422 (64%), Gaps = 12/422 (2%)
Query: 78 PREECGVVGIYGDPE-ASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVF 136
PREECGV G++ E ++L Y L+ALQHRGQE AGI +++ +GLV+ VF
Sbjct: 31 PREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLV-FKDLGLVSQVF 89
Query: 137 TEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGS-VGVAHNGNLVNYRSLREK 195
E L + G +AIGH RYST G + +N QP G+ V + HNGNLVN +L +
Sbjct: 90 DEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAAR 149
Query: 196 LEENGSIFN-----TSSDTEVVLHLIATSKQRPFILRI-VDACEKLKGAYSFVFVTEDKL 249
+ G I ++D++++ L+A + + +D ++GA+ F+ E+ L
Sbjct: 150 ARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTL 209
Query: 250 VAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCL 309
A RDP+G RPL +G+ G VV ASET ALD++ A + R++ PGE+L +D +G++S
Sbjct: 210 YACRDPYGVRPLSLGRLDRGWVV-ASETAALDIVGASFVRDIEPGELLAIDADGVRSTRF 268
Query: 310 VSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVA 369
++P PK C+FE++Y + P S + G+SV+ +R G LA E PVE D+VI VP+SG A
Sbjct: 269 -ANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPA 327
Query: 370 ALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDS 429
A+GYA ++GVP+ QGL+++ YVGRTFI+PSQ IR LG++LKL+P+K V+ GKR++VVDDS
Sbjct: 328 AVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDS 387
Query: 430 IVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRM-SVDEIRE 488
IVRG T +VR+++EAGA E+H+RIA PP+ C+YG+D PS ELI+N + + DE+ E
Sbjct: 388 IVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLE 447
Query: 489 FI 490
+
Sbjct: 448 AV 449
>PUR1_MYCLE (Q50028) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 556
Score = 345 bits (884), Expect = 2e-94
Identities = 183/416 (43%), Positives = 271/416 (64%), Gaps = 11/416 (2%)
Query: 78 PREECGVVGIYGDPE-ASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVF 136
PREECGV G++ E ++L Y L+ALQHRGQE AGI +++ +GLV+ VF
Sbjct: 54 PREECGVFGVWAPGELVAKLTYFGLYALQHRGQEAAGIAVADGSQVLV-FKDLGLVSQVF 112
Query: 137 TEAKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGS-VGVAHNGNLVNYRSLREK 195
E L + G +AIGH RYST G + +N QP GS V + HNGNLVN L +
Sbjct: 113 DEQTLAAMEGHVAIGHCRYSTTGDTTWENAQPVFRNIAAGSGVALGHNGNLVNTAELAAR 172
Query: 196 LEENGSIFN-----TSSDTEVVLHLIATSKQRPFILRI-VDACEKLKGAYSFVFVTEDKL 249
+ G I ++D++++ L+A + + ++ ++GA+ F+ E+ L
Sbjct: 173 ARDAGLIAKRCPAPATTDSDILGALLAHGAADSTLEQAALELLPTVRGAFCLTFMDENTL 232
Query: 250 VAVRDPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCL 309
A RDP+G RPL +G+ G VV ASET LD++ A + R++ PGE+L +D +G++S
Sbjct: 233 YACRDPYGVRPLSLGRLDRGWVV-ASETAGLDIVGASFVRDIEPGELLAIDADGVRSTRF 291
Query: 310 VSHPEPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVA 369
++P PK C+FE++Y + P S + G+SV+ +R G LA E PVE D+VI VP+SG A
Sbjct: 292 -ANPTPKGCVFEYVYLARPDSTLAGRSVHGTRVEIGRRLARECPVEADLVIGVPESGTPA 350
Query: 370 ALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDS 429
A+GYA ++G+ + QGL+++ YVGRTFI+PSQ IR LG++LKL+P+K V+ GKR++VVDDS
Sbjct: 351 AVGYAQESGISYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDS 410
Query: 430 IVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDE 485
+VRG T +VR+++EAGA E+H+RIA PP+ C+YG+D PS ELI+N ++ +E
Sbjct: 411 VVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANVVADEE 466
>PUR1_PYRAB (Q9V253) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 447
Score = 333 bits (853), Expect = 8e-91
Identities = 201/416 (48%), Positives = 273/416 (65%), Gaps = 18/416 (4%)
Query: 79 REECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTE 138
RE+CG+ G+ + +A R Y L ALQHRGQEGAGI +V N +I +++ G GLV++VF E
Sbjct: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRI-RTIKGHGLVSEVFDE 64
Query: 139 AKLDQLPGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNYRSLREKLEE 198
L+ L +AIGHVRYST+G L VQP + +AHNG L N+ LR E
Sbjct: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
Query: 199 NGSIFNTSSDTEVV----LHLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVRD 254
G F++S DTEV+ L+ + K +R V E++KGAYS + + + K++A RD
Sbjct: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRV--FEEVKGAYSILILFDGKIIAARD 179
Query: 255 PFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHPE 314
P GFRPLV G+ FASE AL + E R+V PGEV V+D +S L + +
Sbjct: 180 PVGFRPLVFGE--GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVL-AREK 235
Query: 315 PKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGYA 374
C+FE+IYF+ P S + G +VY +R G LA ESP E DVVIAVPDSG AALG+A
Sbjct: 236 HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
Query: 375 AKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRGT 434
++G+P+ +GLI++ Y+GRTFI PS R L VKLKLSPV+ V+ GKRVV+VDDSIVRGT
Sbjct: 296 HESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
Query: 435 TSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
T ++IV+++++AGA+EVH+RIA PPI CY G+D P+ ELI+ S+++IR+ I
Sbjct: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEI 409
>PUR1_PYRHO (O57979) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPATase)
Length = 449
Score = 332 bits (850), Expect = 2e-90
Identities = 198/417 (47%), Positives = 270/417 (64%), Gaps = 19/417 (4%)
Query: 79 REECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVHNNKIFQSVTGVGLVADVFTE 138
+E+CG+ G Y +A++ Y L ALQHRGQEGAGI +V + I ++V G GLV++VF
Sbjct: 7 KEKCGIFGAYSQ-DATKKTYYGLMALQHRGQEGAGI-SVWDGDI-RTVKGHGLVSEVFKG 63
Query: 139 AKLDQLPGTLAIGHVRYSTAGQSMLKNVQPF---VAGYRFGSVGVAHNGNLVNYRSLREK 195
+ +L G IGHVRYST+G L VQP GY+ V +AHNG L N+ LR
Sbjct: 64 GSIRRLNGNPVIGHVRYSTSGS--LSEVQPLEVECCGYK---VSIAHNGTLTNFLPLRRF 118
Query: 196 LEENGSIFNTSSDTEVVL--HLIATSKQRPFILRIVDACEKLKGAYSFVFVTEDKLVAVR 253
E G F +S DTEV+ L S+ + + E++KGAYS + + KL+AVR
Sbjct: 119 YESRGFKFRSSIDTEVIAVSFLNHYSELKDEFEAMSRVFEEVKGAYSVLMLFNGKLIAVR 178
Query: 254 DPFGFRPLVMGKRSNGAVVFASETCALDLIEAEYEREVYPGEVLVVDKNGLQSLCLVSHP 313
DP GFRPL G + F+SE AL + R+V PGEV+VV K+G +V
Sbjct: 179 DPVGFRPLSFG--AGDGYYFSSEDSALRMFCTNI-RDVSPGEVIVV-KDGEAESKIVGRS 234
Query: 314 EPKQCIFEHIYFSLPSSVVFGKSVYESRRLFGEILATESPVECDVVIAVPDSGVVAALGY 373
E C+FE+IYF+ P S++ G SVY +R G LA ESP E DVVIAVPDSG AALG+
Sbjct: 235 EHAYCVFEYIYFARPDSIINGISVYWARYRMGVELARESPAEGDVVIAVPDSGRTAALGF 294
Query: 374 AAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDLGVKLKLSPVKAVLEGKRVVVVDDSIVRG 433
A ++G+P+ +GLI++ Y+GRTFI PS R++ V+LKLSPVK V++G+R+V+VDDSIVRG
Sbjct: 295 AHESGIPYMEGLIKNRYIGRTFIMPSG--REIKVRLKLSPVKEVIKGRRIVLVDDSIVRG 352
Query: 434 TTSSKIVRLIKEAGAKEVHMRIACPPIIGSCYYGVDTPSSEELISNRMSVDEIREFI 490
TT IV+++++AGA+EVH+RIA PPI CY G+D P+ ELI+ S++EI++ I
Sbjct: 353 TTMKNIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWKSIEEIKKEI 409
>PUR1_HUMAN (Q06203) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPAT)
Length = 517
Score = 325 bits (833), Expect = 2e-88
Identities = 187/445 (42%), Positives = 268/445 (60%), Gaps = 34/445 (7%)
Query: 79 REECGVVGIYGDPE------ASRLCYLALHALQHRGQEGAGIVTVHNNKI--FQSVTGVG 130
REECGV G E + L L LQHRGQE AGIVT + + F+S G+G
Sbjct: 9 REECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMG 68
Query: 131 LVADVFTEAKLDQL-PGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNY 189
LV VFTE L +L L IGH RY+T G+ L+N QPFV G + VAHNG LVN
Sbjct: 69 LVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNA 128
Query: 190 RSLREKLEENGSIFNTSSDTEVVLHLIATSKQRP------FILRIVDACEKLKGAYSFVF 243
LR+KL +G +TSSD+E++ L+A + + ++ RI + ++ AYS +
Sbjct: 129 ARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLI 188
Query: 244 VTEDKLVAVRDPFGFRPLVMGK---------------RSNGAVVFASETCALDLIEAEYE 288
+ D + AVRDP+G RPL +G+ + G VV +SE+C+ I A Y
Sbjct: 189 MHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVV-SSESCSFLSIGARYY 247
Query: 289 REVYPGEVLVVDKNGLQSLCLVSHPEPKQ---CIFEHIYFSLPSSVVFGKSVYESRRLFG 345
REV PGE++ + ++ +Q+L ++S E CIFE++YF+ P S+ + VY R G
Sbjct: 248 REVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG 307
Query: 346 EILATESPVECDVVIAVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDL 405
+ LA E+PV+ D+V VP+S AAL YA K G+P+ + L ++ YVGRTFI+P+ ++R L
Sbjct: 308 QQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQL 367
Query: 406 GVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCY 465
GV K + +GKR+V+VDDSIVRG T S I++L+KE+GAKEVH+R+A PPI C+
Sbjct: 368 GVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCF 427
Query: 466 YGVDTPSSEELISNRMSVDEIREFI 490
G++ P+ EELI+N+ D + E++
Sbjct: 428 MGINIPTKEELIANKPEFDHLAEYL 452
>PUR1_CHICK (P28173) Amidophosphoribosyltransferase precursor (EC
2.4.2.14) (Glutamine phosphoribosylpyrophosphate
amidotransferase) (ATASE) (GPAT)
Length = 510
Score = 325 bits (832), Expect = 2e-88
Identities = 188/445 (42%), Positives = 266/445 (59%), Gaps = 34/445 (7%)
Query: 79 REECGVVGIYG------DPEASRLCYLALHALQHRGQEGAGIVTV--HNNKIFQSVTGVG 130
REECGV G + + + L L LQHRGQE AGIVT +++ F+ G+G
Sbjct: 9 REECGVFGCIAAGVWPTELDVPHVITLGLVGLQHRGQESAGIVTSDGESSQAFKVHKGMG 68
Query: 131 LVADVFTEAKLDQL-PGTLAIGHVRYSTAGQSMLKNVQPFVAGYRFGSVGVAHNGNLVNY 189
L+ VF L +L L IGH RYST+G S L+N QPFV G + VAHNG L N
Sbjct: 69 LINHVFNADSLKKLYVSNLGIGHTRYSTSGISELQNCQPFVVETLHGKIAVAHNGELTNA 128
Query: 190 RSLREKLEENGSIFNTSSDTEVVLHLIA------TSKQRPFILRIVDACEKLKGAYSFVF 243
LR KL +G +TSSD+E++ L+A ++ RI + + +YS +
Sbjct: 129 VRLRRKLMRHGVGLSTSSDSELITQLLAFTPPLENDDTADWVARIKNLMNETPTSYSLLI 188
Query: 244 VTEDKLVAVRDPFGFRPLVMGK---------------RSNGAVVFASETCALDLIEAEYE 288
+ +D + AVRDP+G RPL +G+ + G VV +SE+C+ I AEY
Sbjct: 189 MHKDIIYAVRDPYGNRPLCIGRLIPVGDINGKGKDNSETEGWVV-SSESCSFLSIGAEYY 247
Query: 289 REVYPGEVLVVDKNGLQSLCLVSHPEPKQ---CIFEHIYFSLPSSVVFGKSVYESRRLFG 345
REV PGE++ + + +Q+L +V PE CIFE++YF+ P S+ G+ VY RR G
Sbjct: 248 REVLPGEIVKISRYDVQTLDVVPRPEGDPSAFCIFEYVYFARPDSIFEGQMVYSVRRRCG 307
Query: 346 EILATESPVECDVVIAVPDSGVVAALGYAAKAGVPFQQGLIRSHYVGRTFIEPSQKIRDL 405
+ LA E+PVE D+V VP+S AALGYA K G+P+ + L ++ YVGRTFI+P+ ++R L
Sbjct: 308 QQLAIEAPVEADLVSTVPESATPAALGYAQKCGLPYVEVLCKNRYVGRTFIQPNMRLRQL 367
Query: 406 GVKLKLSPVKAVLEGKRVVVVDDSIVRGTTSSKIVRLIKEAGAKEVHMRIACPPIIGSCY 465
GV K + +GKRVV++DDSIVRG T S I++L++E+GAKEVH+R+A PPI CY
Sbjct: 368 GVAKKFGVLSDNFKGKRVVIIDDSIVRGNTISPIIKLLRESGAKEVHIRVASPPIRFPCY 427
Query: 466 YGVDTPSSEELISNRMSVDEIREFI 490
G++ P+ EELI+NR ++ +I
Sbjct: 428 MGINIPTKEELIANRPEFHDLANYI 452
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.136 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,754,187
Number of Sequences: 164201
Number of extensions: 2716226
Number of successful extensions: 8168
Number of sequences better than 10.0: 318
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 7604
Number of HSP's gapped (non-prelim): 344
length of query: 490
length of database: 59,974,054
effective HSP length: 114
effective length of query: 376
effective length of database: 41,255,140
effective search space: 15511932640
effective search space used: 15511932640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Lotus: description of TM0231b.3