BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0228a.2
         (510 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02         106  1e-22
BDF1_YEAST (P35817) BDF1 protein                                       99  3e-20
BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3 (Bromodomai...    99  3e-20
BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like...    95  4e-19
BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3 prot...    94  8e-19
BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1 prot...    94  1e-18
BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic ch...    93  1e-18
FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chor...    91  9e-18
YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02           84  7e-16
BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2...    76  2e-13
BA2B_HUMAN (Q9UIF8) Bromodomain adjacent to zinc finger domain 2...    74  9e-13
BA2A_MOUSE (Q91YE5) Bromodomain adjacent to zinc finger domain 2...    71  8e-12
CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48)                  70  2e-11
WDR9_HUMAN (Q9NSI6) WD-repeat protein 9                                69  2e-11
TF1A_HUMAN (O15164) Transcription intermediary factor 1-alpha (T...    69  4e-11
CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)                  68  5e-11
BA2A_HUMAN (Q9UIF9) Bromodomain adjacent to zinc finger domain 2...    68  5e-11
GCN5_YEAST (Q03330) Histone acetyltransferase GCN5 (EC 2.3.1.48)       67  8e-11
P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48)          67  1e-10
TF1A_MOUSE (Q64127) Transcription intermediary factor 1-alpha (T...    67  1e-10

>YCK2_SCHPO (Q9Y7N0) Hypothetical bromodomain protein C1450.02
          Length = 578

 Score =  106 bits (265), Expect = 1e-22
 Identities = 53/112 (47%), Positives = 72/112 (63%), Gaps = 6/112 (5%)

Query: 77  RKGSTQ---CAAILKCLMSYPY---SWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKL 130
           RK ++Q   C+ +LK L    Y   ++ F +PVDPVA + PDYF +I +PMDL TI SKL
Sbjct: 251 RKNNSQMRFCSTVLKELYKRQYESFAFPFYQPVDPVACDCPDYFDVIKEPMDLSTIQSKL 310

Query: 131 KKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDMDK 182
            KN YS +EEF +D+ L F+N  TYNPP   VH+M ++L  +F  KW+   K
Sbjct: 311 NKNEYSTLEEFESDILLMFNNCFTYNPPGTPVHVMGRQLENVFKEKWEARPK 362



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 83/303 (27%), Positives = 124/303 (40%), Gaps = 40/303 (13%)

Query: 10  TRKLKIKFSTKRIEVDPGQKCEFGQRGLQTDENGRCNSAEKLF-KPDSIKRGPPEGFEGQ 68
           +R+ ++K  TK    + G     G   +Q+ +     + E L  K DS   G   G   Q
Sbjct: 5   SRENEVKAETKDEIANDGSPQLNGDNNIQSSDGHNDENEESLSRKRDS--SGATVGDLKQ 62

Query: 69  KEKR-----------QKIDRKG-----STQCAAILKCLMSYPYSWVFNKPVDPVALNIPD 112
           +EK            +KI   G        C AI++ L     S  F  PVDP+  NIPD
Sbjct: 63  EEKESMPKKEPEPTVKKIRGSGMPPPQQKYCLAIVRQLKRTKNSAPFKVPVDPIKQNIPD 122

Query: 113 YFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQI 172
           Y  I+  PMDLGTI  KL    YS  +EF  D+ L FSN   YN   + V  M K L ++
Sbjct: 123 YPTIVKNPMDLGTIEKKLTSYEYSVPQEFIDDMNLMFSNCFLYNGTESPVGSMGKALQEV 182

Query: 173 FDSKWKDMDKKWKCEDELGKSVTGTIKETARKSCNVMHPRQKDTFPKKSQVSEHKRVLKI 232
           F+ + K +        +  +     +K++ +KS +   PR              +R   +
Sbjct: 183 FERQLKQL-------PDAEQPAAAPVKKSKQKSASTAPPRT-------------RRNSSV 222

Query: 233 SSLAARDAKVEVPKLSQVHCKSIEKDLIKGSEERDRIAPGAVAFKQKRQIKSTS-PLERK 291
           SS +A  A    PK +        K   + +  + R     +    KRQ +S + P  + 
Sbjct: 223 SSTSASVAASTAPKAASPAVLPEGKPRRRKNNSQMRFCSTVLKELYKRQYESFAFPFYQP 282

Query: 292 SDP 294
            DP
Sbjct: 283 VDP 285


>BDF1_YEAST (P35817) BDF1 protein
          Length = 686

 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 49/118 (41%), Positives = 75/118 (63%), Gaps = 4/118 (3%)

Query: 65  FEGQKEKRQKIDRKGSTQCAAILKCLMSYP---YSWVFNKPVDPVALNIPDYFAIIAKPM 121
           +E +K K +++ ++    C ++LK LM+     Y++ F +PVDPV++N+P YF  + +PM
Sbjct: 304 YESKKPKSKRL-QQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPM 362

Query: 122 DLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKD 179
           DLGTI+ KL    Y  +E+F  DVRL F N  T+NP    V+MM   L ++F+SKW D
Sbjct: 363 DLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWAD 420



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 57/225 (25%), Positives = 92/225 (40%), Gaps = 23/225 (10%)

Query: 27  GQKCEFGQRGLQTDENGRCNSAEKLFK----------PDSIKRGPPEGFEGQKEKRQKID 76
           G   E  Q+GL+ +E G+    E L +          P      PP   +     +  I 
Sbjct: 91  GSGAEDEQQGLKKEEGGQGTKQEDLDENSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIP 150

Query: 77  RKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYS 136
           +         +K +     +  F +PVDPV L+IP YF  I +PMDL TI  KL    Y 
Sbjct: 151 KHQQKHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYE 210

Query: 137 CVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDMDKKWKCEDELGKSVTG 196
             E+   D  L  +N++ +N P+  +  MA+ +   F+    +M  K      + K    
Sbjct: 211 VPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAK-DAPPVIAKGRRS 269

Query: 197 TIKETA------------RKSCNVMHPRQKDTFPKKSQVSEHKRV 229
           + +E A            R    +  P+ KD +P +S+  + KR+
Sbjct: 270 SAQEDAPIVIRRAQTHNGRPKRTIHPPKSKDIYPYESKKPKSKRL 314


>BRD3_MOUSE (Q8K2F0) Bromodomain-containing protein 3
           (Bromodomain-containing FSH-like protein FSRG2)
          Length = 726

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 99/401 (24%), Positives = 168/401 (41%), Gaps = 57/401 (14%)

Query: 61  PPEGFEGQKEKRQKIDRKGSTQ-----CAAILKCLMSYP---YSWVFNKPVDPVALNIPD 112
           PP+      E  Q   +KG        C +IL+ ++S     Y+W F KPVD  AL + D
Sbjct: 287 PPKKDLEDGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHD 346

Query: 113 YFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQI 172
           Y  II  PMDL T+  K+    Y   + FAAD+RL FSN   YNPP ++V  MA++L  +
Sbjct: 347 YHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDV 406

Query: 173 FDSKWKDMDKKWKCEDELGKSVTGTIKETARKSCNVMHPRQKDTFPKKSQVSEHKRVLKI 232
           F+ ++  M  +      L       + + A  S       ++ +    S  SE +R  ++
Sbjct: 407 FEMRFAKMPDEPMEAPALPAPTAPIVSKGAESS----RSSEESSSDSGSSDSEEERATRL 462

Query: 233 SSL------------AARDAKVEVPKLSQV----------HCKSIEKDLIKGSEERDRIA 270
           + L            A   A V  PK  +             K  EK+  K   E ++ A
Sbjct: 463 AELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKDKDKEKEKHKAKSEEEKKA 522

Query: 271 PGAVAFKQKRQIKSTSPLERKSDPDSDGAVSSLDSEHVYPGSQHATPATDASSGEVWSTP 330
             A A KQ +Q         K  P      ++  S  +  G + A+ + D+   E     
Sbjct: 523 KAAPAAKQAQQ---------KKAPTKKANSTTTASRQLKKGGKQASASYDSEEEE----E 569

Query: 331 DFPVQLSPKKAL-----RAAMLKSRFADTILKAQQKTLLEHGDKGDPLKMQ-LEKERLER 384
             P+    K+ L     R    K      I+++++ +L +       +  + L+   L  
Sbjct: 570 GLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRE 629

Query: 385 IQREERARIEAQ----IKTAEAAARARAEEELRQQREKERE 421
           ++R  ++ ++ +    + T+     A+++EEL Q+++KE E
Sbjct: 630 LERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELE 670



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 44/130 (33%), Positives = 66/130 (49%), Gaps = 2/130 (1%)

Query: 54  PDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDY 113
           P  +   PPE     K  R+    +       ++K L  + ++W F +PVD + LN+PDY
Sbjct: 15  PGPVNPPPPEVSNPSKPGRKTNQLQYMQN--VVVKTLWKHQFAWPFYQPVDAIKLNLPDY 72

Query: 114 FAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIF 173
             II  PMD+GTI  +L+ N Y    E   D    F+N   YN P +D+ +MA+ L +IF
Sbjct: 73  HKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 132

Query: 174 DSKWKDMDKK 183
             K   M ++
Sbjct: 133 LQKVAQMPQE 142


>BRD3_HUMAN (Q15059) Bromodomain-containing protein 3 (RING3-like
           protein)
          Length = 726

 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 102/396 (25%), Positives = 163/396 (40%), Gaps = 49/396 (12%)

Query: 61  PPEGFEGQKEKRQKIDRKGSTQ-----CAAILKCLMSYP---YSWVFNKPVDPVALNIPD 112
           PP+      E  Q   +KG        C +IL+ ++S     Y+W F KPVD  AL + D
Sbjct: 288 PPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHD 347

Query: 113 YFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQI 172
           Y  II  PMDL T+  K+    Y   + FAADVRL FSN   YNPP ++V  MA++L  +
Sbjct: 348 YHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDV 407

Query: 173 FDSKWKDMDKKWKCEDELGKSVTGTIKETARKSCNVMHPRQKDTFPKKSQVSEHKRVLKI 232
           F+ ++  M  +      L       + + A  S       ++ +    S  SE +R  ++
Sbjct: 408 FEMRFAKMPDEPVEAPALPAPAAPMVSKGAESS----RSSEESSSDSGSSDSEEERATRL 463

Query: 233 SSL------------AARDAKVEVPKLSQVHC----------KSIEKDLIKGSEERD-RI 269
           + L            A   A V  PK  +             K  EK  +K  EE+  ++
Sbjct: 464 AELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKV 523

Query: 270 APGAVAFKQKR----QIKSTSPLERKSDPDSDGAVSSLDSEHVYPGSQHATPATDASSGE 325
           AP A   +QK+    +  ST+   R+       A +S DSE    G   +       S +
Sbjct: 524 APPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLD 583

Query: 326 VWSTPDFPVQLSPKKALRAAMLKSRFADTILKAQQKTLLEHGDKGDPLKMQLEKERLERI 385
           +   P        K      +++SR          +  ++          +LE+     +
Sbjct: 584 INRLP------GEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCL 637

Query: 386 QREERARIEAQIKTAEAAARARAEEELRQQREKERE 421
           Q+++R    A  K   A    +++EEL Q+++KE E
Sbjct: 638 QKKQRKPFSASGKKQAA----KSKEELAQEKKKELE 669



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 44/130 (33%), Positives = 66/130 (49%), Gaps = 2/130 (1%)

Query: 54  PDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDY 113
           P  +   PPE     K  R+    +       ++K L  + ++W F +PVD + LN+PDY
Sbjct: 16  PGPVNPPPPEVSNPSKPGRKTNQLQYMQN--VVVKTLWKHQFAWPFYQPVDAIKLNLPDY 73

Query: 114 FAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIF 173
             II  PMD+GTI  +L+ N Y    E   D    F+N   YN P +D+ +MA+ L +IF
Sbjct: 74  HKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 133

Query: 174 DSKWKDMDKK 183
             K   M ++
Sbjct: 134 LQKVAQMPQE 143


>BRD2_HUMAN (P25440) Bromodomain-containing protein 2 (RING3
           protein) (O27.1.1)
          Length = 801

 Score = 94.0 bits (232), Expect = 8e-19
 Identities = 52/123 (42%), Positives = 70/123 (56%), Gaps = 4/123 (3%)

Query: 61  PPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYP---YSWVFNKPVDPVALNIPDYFAII 117
           P    + Q  K+ K+  +    C  ILK L+S     Y+W F KPVD  AL + DY  II
Sbjct: 332 PDSQQQHQSSKKGKLSEQ-LKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDII 390

Query: 118 AKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKW 177
             PMDL T+  K++   Y   +EFAADVRL FSN   YNPP +DV  MA++L  +F+ ++
Sbjct: 391 KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 450

Query: 178 KDM 180
             M
Sbjct: 451 AKM 453



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 38/98 (38%), Positives = 57/98 (57%)

Query: 86  ILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADV 145
           ++K L  + ++W F +PVD V L +PDY  II +PMD+GTI  +L+ N Y    E   D 
Sbjct: 86  VMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDF 145

Query: 146 RLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDMDKK 183
              F+N   YN P +D+ +MA+ L +IF  K   M ++
Sbjct: 146 NTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQE 183


>BRD4_HUMAN (O60885) Bromodomain-containing protein 4 (HUNK1
           protein)
          Length = 1362

 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 82/280 (29%), Positives = 120/280 (42%), Gaps = 31/280 (11%)

Query: 38  QTDENGRCNSAEKLFKPDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYP--- 94
           Q  E+ R     K   PDS +   PE       K  K+  +    C+ ILK + +     
Sbjct: 320 QRRESSRPVKPPKKDVPDSQQHPAPE-------KSSKVSEQLKC-CSGILKEMFAKKHAA 371

Query: 95  YSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMT 154
           Y+W F KPVD  AL + DY  II  PMD+ TI SKL+   Y   +EF ADVRL FSN   
Sbjct: 372 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYK 431

Query: 155 YNPPHNDVHMMAKELNQIFDSKWKDMDKKWKCEDELGKSVTGTIKETARKSCNVMHPRQK 214
           YNPP ++V  MA++L  +F+ ++       K  DE  + V             V+ P   
Sbjct: 432 YNPPDHEVVAMARKLQDVFEMRFA------KMPDEPEEPVVAVSSPAVPPPTKVVAPPSS 485

Query: 215 DTFPKKSQV--------SEHKRVLKISSL-----AARDAKVEVPKLSQVHCKSIEKDLIK 261
                 S          SE +R  +++ L     A  +    + +  Q   K  EKD  +
Sbjct: 486 SDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKE 545

Query: 262 GSEERDRIAPGAVAFKQKRQIKSTSPLERKSDPDSDGAVS 301
             +E+ +     V   +K + K   P + K +  S+  VS
Sbjct: 546 KKKEKHK-RKEEVEENKKSKAKEPPPKKTKKNNSSNSNVS 584



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 52/149 (34%), Positives = 77/149 (50%), Gaps = 15/149 (10%)

Query: 61  PPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKP 120
           PPE     K KRQ    +   +   +LK L  + ++W F +PVD V LN+PDY+ II  P
Sbjct: 47  PPETSNPNKPKRQTNQLQYLLR--VVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTP 104

Query: 121 MDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDM 180
           MD+GTI  +L+ N Y   +E   D    F+N   YN P +D+ +MA+ L ++F  K  ++
Sbjct: 105 MDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164

Query: 181 DKKWKCEDEL----------GKSVTGTIK 199
             +   E E+          G+  TGT K
Sbjct: 165 PTE---ETEIMIVQAKGRGRGRKETGTAK 190



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 45/190 (23%), Positives = 88/190 (45%), Gaps = 29/190 (15%)

Query: 240  AKVEVPKLSQVHCKSIEKDLIKGSEERDRIAPGAVAFKQKRQIKSTSPLERKSDPD--SD 297
            A V +P+  ++    + + +I+  E+     P     K K++ +  +P+  K D    + 
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQN--APPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1199

Query: 298  GAVSSLDSEHVYPGSQHATPATDASSGEVWSTPDFPVQLSPKKALRAAMLKSRFADTILK 357
            G+ +SL  +H        TP++ A S    S+  F       +  R A  +    +  LK
Sbjct: 1200 GSWASLVQKHP------TTPSSTAKS----SSDSF-------EQFRRAAREKEEREKALK 1242

Query: 358  AQQKTLLEHGDKGDPLKMQLEKERLERIQREERARIEAQIKTAEAAARARAEEELRQQRE 417
            AQ     EH +K    K +L +ER+ R + +E A  +A+    EA  R   +++ RQ+++
Sbjct: 1243 AQA----EHAEKE---KERLRQERM-RSREDEDALEQARRAHEEARRRQEQQQQQRQEQQ 1294

Query: 418  KEREAARAAI 427
            ++++   AA+
Sbjct: 1295 QQQQQQAAAV 1304


>BRD4_MOUSE (Q9ESU6) Bromodomain-containing protein 4 (Mitotic
           chromosome-associated protein) (MCAP)
          Length = 1400

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 80/271 (29%), Positives = 120/271 (43%), Gaps = 19/271 (7%)

Query: 41  ENGRCNSAEKLFKPDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYP---YSW 97
           E+ R     K   PDS +   PE       K  KI  +    C+ ILK + +     Y+W
Sbjct: 324 ESSRPVKPPKKDVPDSQQHPGPE-------KSSKISEQLKC-CSGILKEMFAKKHAAYAW 375

Query: 98  VFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNP 157
            F KPVD  AL + DY  II  PMD+ TI SKL+   Y   +EF ADVRL FSN   YNP
Sbjct: 376 PFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNP 435

Query: 158 PHNDVHMMAKELNQIFDSKWKDM--DKKWKCEDELGKSVTGTIKETARKSCNVMHPRQKD 215
           P ++V  MA++L  +F+ ++  M  + +         +V    K  A  S +        
Sbjct: 436 PDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPPTKVVAPPSSSDSSSDSSS 495

Query: 216 TFPKKSQVSEHKRVLKISSL-----AARDAKVEVPKLSQVHCKSIEKDLIKGSEERDRIA 270
                +  SE +R  +++ L     A  +    + +  Q   K  EKD  +  +E+ +  
Sbjct: 496 DSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHK-K 554

Query: 271 PGAVAFKQKRQIKSTSPLERKSDPDSDGAVS 301
              V   +K + K   P + K +  S+  VS
Sbjct: 555 KEEVEENKKSKTKELPPKKTKKNNSSNSNVS 585



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 45/120 (37%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 61  PPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKP 120
           PPE     K KRQ    +   +   +LK L  + ++W F +PVD V LN+PDY+ II  P
Sbjct: 47  PPETSNPNKPKRQTNQLQYLLR--VVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTP 104

Query: 121 MDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDM 180
           MD+GTI  +L+ N Y   +E   D    F+N   YN P +D+ +MA+ L ++F  K  ++
Sbjct: 105 MDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 48/195 (24%), Positives = 84/195 (42%), Gaps = 37/195 (18%)

Query: 240  AKVEVPKLSQVHCKSIEKDLIKGSEERDRIAPGAVAFKQKRQIKSTSPLERKSDPD--SD 297
            A V +P+  ++    I + +I+  E+     P     K K++ +  +P+  K D    + 
Sbjct: 1178 APVHLPQRPEMKPVDIGRPVIRPPEQS--APPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1235

Query: 298  GAVSSLDSEHVYPGSQHATPATDASSGEVWSTPDFPVQLSPKKALRAAMLKSRFADTILK 357
            G+ +SL  +H        TP++ A S    S+  F       +  R A  +    +  LK
Sbjct: 1236 GSWASLVQKHP------TTPSSTAKS----SSDSF-------EHFRRAAREKEEREKALK 1278

Query: 358  AQQKTLLEHGDKGDPLKMQLEKERLERIQREERARIEAQIKTAEAAARARAEEELRQQRE 417
            AQ     EH +K        EKERL    R+ER R        E A RA  E   RQ+++
Sbjct: 1279 AQA----EHAEK--------EKERL----RQERMRSREDEDALEQARRAHEEARRRQEQQ 1322

Query: 418  KEREAARAAIEEMKR 432
            ++++  R   ++ ++
Sbjct: 1323 QQQQQQRQEQQQQQQ 1337


>FSH_DROME (P13709) Female sterile homeotic protein (Fragile-chorion
           membrane protein)
          Length = 2038

 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 46/101 (45%), Positives = 60/101 (58%), Gaps = 3/101 (2%)

Query: 83  CAAILKCLMSYP---YSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVE 139
           C  ILK L S     Y+W F KPVD   L + DY  II KPMDLGT+  K+    Y    
Sbjct: 484 CNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAP 543

Query: 140 EFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDM 180
           EFAADVRL F+N   YNPP +DV  M ++L  +F+ ++ ++
Sbjct: 544 EFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANI 584



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 39/98 (39%), Positives = 58/98 (58%)

Query: 86  ILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADV 145
           ++K +  + +SW F +PVD   LN+PDY  II +PMD+GTI  +L+ N Y   +E   D 
Sbjct: 46  VMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDF 105

Query: 146 RLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDMDKK 183
              F+N   YN P  DV +MA+ L ++F  K + M K+
Sbjct: 106 NTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKE 143


>YK82_SCHPO (Q9HGP4) Hypothetical bromodomain protein C631.02
          Length = 727

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 41/98 (41%), Positives = 57/98 (57%), Gaps = 3/98 (3%)

Query: 83  CAAILKCLMSYP---YSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVE 139
           C ++LK L+      Y++ F KPV+P A   PDYF +I  PMDLGT+ +KL  N Y+ ++
Sbjct: 397 CQSVLKELLKKQHEAYAYPFYKPVNPTACGCPDYFKVIKHPMDLGTMQNKLNHNEYASMK 456

Query: 140 EFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKW 177
            F AD+ L F N   +N     VH+M K+L  IF   W
Sbjct: 457 AFEADMVLMFKNCYKFNSAGTPVHLMGKKLESIFQKLW 494



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 42/115 (36%), Positives = 58/115 (49%)

Query: 66  EGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGT 125
           E  K++   + ++      A+L+ L     S  F  PVDPV  NIPDY  II  P+DLGT
Sbjct: 221 ENDKDQYPPMTKEQHKYIHAMLRQLRRGRDSIPFRAPVDPVKQNIPDYPTIIKNPIDLGT 280

Query: 126 ISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDM 180
           +  K    VYS  + F  D+ L FSN   YN   + V +M K L   F+ + K +
Sbjct: 281 MQKKFSSGVYSSAQHFIDDMNLMFSNCFLYNGTESPVGVMGKNLQATFERQLKQL 335


>BA2B_CHICK (Q9DE13) Bromodomain adjacent to zinc finger domain 2B
            (Extracellular matrix protein F22)
          Length = 2130

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 45/133 (33%), Positives = 67/133 (49%), Gaps = 3/133 (2%)

Query: 50   KLFKPDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALN 109
            K+ +  S+ +G  E F   K K ++ D K    C+ IL  L ++  +W F  PV+     
Sbjct: 1999 KMDESVSVSQGKQENFTAIK-KPKRDDSKDLAICSMILSELETHEDAWPFLLPVNLKL-- 2055

Query: 110  IPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKEL 169
            +P Y  +I KPMD  TI  KL    Y  VE F+ DVRL F N  T+N   +D+      +
Sbjct: 2056 VPGYKKVIKKPMDFSTIRDKLTSGQYPNVEAFSLDVRLVFDNCETFNEDDSDIGRAGHNM 2115

Query: 170  NQIFDSKWKDMDK 182
             + F+ KW ++ K
Sbjct: 2116 RKYFEKKWTEIFK 2128



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 35/123 (28%), Positives = 63/123 (50%), Gaps = 14/123 (11%)

Query: 339 KKALRAAMLKS--RFADTILKAQQKTLLEHGDKGDPLKMQLEKERLERIQREERARIEAQ 396
           ++A  A +L++  R  +  ++ QQ  LL+H         +LE+ RL+ ++RE R +    
Sbjct: 887 EEAANAKLLEAEKRIKEKEMRRQQAVLLKH--------QELERHRLD-MERERRRQHMML 937

Query: 397 IKTAEAAARARAEEELRQQREKEREAARAAIEEMKRTVEIEHNLEIVKELETLSGCTLSY 456
           +K  EA  +A  +E L+Q++  E+   +    E +R +E+E   E+ K  E +  C    
Sbjct: 938 MKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRR-LELEMAKELKKPNEDM--CLADQ 994

Query: 457 KAL 459
           KAL
Sbjct: 995 KAL 997



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 41/166 (24%), Positives = 72/166 (42%), Gaps = 25/166 (15%)

Query: 290 RKSDPDSDGAVSSLDSEHVYPGSQHATPATDASSGEVWSTPDFPVQLSPKKALRAAMLKS 349
           RK  P + G+   LDS             TDA         +   Q +  K LR    + 
Sbjct: 779 RKGRPPNVGSTEFLDS-------------TDAKLLRKLQAQEIARQAAQIKLLRKLQKQE 825

Query: 350 RFADTILKAQQKTLLEHGDKG---DPLKMQLEKERLERIQ-----REERAR--IEAQIKT 399
           +        +Q+ ++   +K    + +K+  ++E+++RIQ     +E RA+  +EA+ K 
Sbjct: 826 QARAAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKK 885

Query: 400 AEAAARARAEEELRQQREKEREAARAAIEEMKRTVEIEHNLEIVKE 445
            E AA A+  E   ++R KE+E  R     +K      H L++ +E
Sbjct: 886 KEEAANAKLLEA--EKRIKEKEMRRQQAVLLKHQELERHRLDMERE 929


>BA2B_HUMAN (Q9UIF8) Bromodomain adjacent to zinc finger domain 2B
            (hWALp4)
          Length = 1972

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 45/133 (33%), Positives = 64/133 (47%), Gaps = 3/133 (2%)

Query: 50   KLFKPDSIKRGPPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALN 109
            K+ +  SI     E F   K K ++ D K    C+ IL  + ++  +W F  PV+     
Sbjct: 1841 KMEENTSINLSKQESFTSVK-KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKL-- 1897

Query: 110  IPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKEL 169
            +P Y  +I KPMD  TI  KL    Y  +E FA DVRL F N  T+N   +D+      +
Sbjct: 1898 VPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNM 1957

Query: 170  NQIFDSKWKDMDK 182
             + F+ KW D  K
Sbjct: 1958 RKYFEKKWTDTFK 1970



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 6/114 (5%)

Query: 335 QLSPKKALRAAMLKSRFADTILKAQQKTLLEHGDKGDPLKMQLEKERLERIQREERARIE 394
           Q+  +K LRA  +         +A    LLE   +    +M+ ++  L + Q  ER R  
Sbjct: 756 QIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQH 815

Query: 395 AQI-KTAEAAARARAEEELRQQREKEREAARAAIEEMKRTVEIEHNLEIVKELE 447
             + K  EA  +A  +E L+Q++  E+   +    E +R       LE+ KEL+
Sbjct: 816 MMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRL-----ELEMAKELK 864


>BA2A_MOUSE (Q91YE5) Bromodomain adjacent to zinc finger domain 2A
            (Transcription termination factor-I interacting protein
            5) (TTF-I interacting protein 5) (Tip5)
          Length = 1850

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 39/126 (30%), Positives = 65/126 (50%), Gaps = 4/126 (3%)

Query: 56   SIKRGPPEGFEGQKEKRQKIDRKGS--TQCAAILKCLMSYPYSWVFNKPVDPVALNIPDY 113
            ++ R P +G    K +R  +    S  T C  IL  + S+  +W F +PV+P  ++   Y
Sbjct: 1718 AVPRYPEDGLSPPKRRRHSMRSHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVS--GY 1775

Query: 114  FAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQIF 173
              +I  PMD  T+  +L +  Y+  EEFAAD  L F N  T+N   ++V      + + F
Sbjct: 1776 RRVIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHVMRRFF 1835

Query: 174  DSKWKD 179
            +S+W++
Sbjct: 1836 ESRWEE 1841



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 28/95 (29%), Positives = 57/95 (59%), Gaps = 5/95 (5%)

Query: 369 KGDPLKMQLEKERL-ERIQREERARIEAQIKTA-EAAARARAEEELR-QQREKEREAARA 425
           K +  KM+ ++E+L E+++RE++ +++A+ K    A    RA++ L  Q+R +E++  +A
Sbjct: 708 KAEKEKMKTKQEKLKEKVKREKKEKVKAKGKEGPRARPSCRADKTLATQKRLEEQQRQQA 767

Query: 426 AIEEMKRTVE--IEHNLEIVKELETLSGCTLSYKA 458
            +EEMK+  E     + + + +   + G TLS +A
Sbjct: 768 ILEEMKKPTEGMCLSDHQPLPDFTRIPGLTLSSRA 802


>CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48)
          Length = 2441

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 35/83 (42%), Positives = 47/83 (56%)

Query: 94   PYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAM 153
            P S  F +PVDP  L IPDYF I+  PMDL TI  KL    Y    ++  DVRL F+NA 
Sbjct: 1107 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAW 1166

Query: 154  TYNPPHNDVHMMAKELNQIFDSK 176
             YN   + V+    +L ++F+ +
Sbjct: 1167 LYNRKTSRVYKFCSKLAEVFEQE 1189


>WDR9_HUMAN (Q9NSI6) WD-repeat protein 9
          Length = 2269

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 59/211 (27%), Positives = 90/211 (41%), Gaps = 14/211 (6%)

Query: 16   KFSTKRIEVDPGQKCEFGQRGLQTDENGRCNSAEKLFKPDSIKR--GPPEGFEGQKEKRQ 73
            K + + ++    Q C        T EN   N AE L   D  K   G     +G+K  R 
Sbjct: 1252 KITDQLLKFIKNQHCTNISELSNTSENDEQN-AEDLDDSDLPKTSSGRRRVHDGKKSIRA 1310

Query: 74   K--IDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLK 131
               ++     QC  ++  +     S  F +PVD V    PDY  II  PMD GT+   L 
Sbjct: 1311 TNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLV--EYPDYRDIIDTPMDFGTVRETLD 1368

Query: 132  KNVYSCVEEFAADVRLTFSNAMTYNP-PHNDVHMMAKELNQIFDSKWKDMDKKWKCEDEL 190
               Y    EF  D+RL FSNA  Y P   + ++ M   L+ +F+ K K +   +K   + 
Sbjct: 1369 AGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKF 1428

Query: 191  GKSVTGTIKETARKSCNVMHPRQKDTFPKKS 221
             + +  + +   R++C      + D+ P KS
Sbjct: 1429 NEKLRRSQRFKQRQNC------KGDSQPNKS 1453



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 7/109 (6%)

Query: 61   PPEGFEGQKEKRQKIDRKGSTQCAAILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKP 120
            P  G  GQK + ++ DR  S      +  L++   +  F  PVD      P Y  ++A P
Sbjct: 1152 PQAGEWGQKSRDEECDRIISG-----IDQLLNLDIAAAFAGPVD--LCTYPKYCTVVAYP 1204

Query: 121  MDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKEL 169
             DL TI  +L    Y  +     +VR    NA T+N P + +   AK++
Sbjct: 1205 TDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253


>TF1A_HUMAN (O15164) Transcription intermediary factor 1-alpha
            (TIF1-alpha) (Tripartite motif-containing protein 24)
          Length = 1050

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 8/141 (5%)

Query: 45   CNSAEKLFKPDSIKRGPPEGFEGQKEKRQ---KIDRKGSTQCAAILKCLMSYPYSWVFNK 101
            C     L KP+            +K+K +   K+      +C  +L  L  +  S  F  
Sbjct: 867  CTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQ- 925

Query: 102  PVDPVALNIPDYFAIIAKPMDLGTISSKLKK--NVYSCVEEFAADVRLTFSNAMTYNPPH 159
              DPV L +PDY+ II  PMDL TI  +L++  ++YS  E+F AD RL F N   +N P 
Sbjct: 926  --DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD 983

Query: 160  NDVHMMAKELNQIFDSKWKDM 180
            ++V     +L   F+   K++
Sbjct: 984  SEVANAGIKLENYFEELLKNL 1004


>CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)
          Length = 2442

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 54/197 (27%), Positives = 85/197 (42%), Gaps = 28/197 (14%)

Query: 8    VPTRKLKIKFSTKRIEVDPGQ-----KCEFGQRGLQ--TDENGRCNSAEKLFKPDSIKRG 60
            VP  ++K +   +  E DPG+     + E  +  LQ  +      + AE+  +P  +   
Sbjct: 992  VPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEK 1051

Query: 61   PPEGFEGQKEKRQKIDRKGSTQCAA-------------ILKCLMSY--------PYSWVF 99
             PE     KE+ +      ++Q  +             + + LM          P S  F
Sbjct: 1052 KPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPF 1111

Query: 100  NKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPH 159
             +PVDP  L IPDYF I+  PMDL TI  KL    Y    ++  DV L F+NA  YN   
Sbjct: 1112 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1171

Query: 160  NDVHMMAKELNQIFDSK 176
            + V+    +L ++F+ +
Sbjct: 1172 SRVYKFCSKLAEVFEQE 1188


>BA2A_HUMAN (Q9UIF9) Bromodomain adjacent to zinc finger domain 2A
            (Transcription termination factor-I interacting protein
            5) (TTF-I interacting protein 5) (Tip5) (hWALp3)
          Length = 1878

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 41/128 (32%), Positives = 64/128 (49%), Gaps = 4/128 (3%)

Query: 54   PDSIKRGPPEGFEGQKEKRQKIDRKGS--TQCAAILKCLMSYPYSWVFNKPVDPVALNIP 111
            P +  R   EG    K +R  +    S  T C  IL  + S+  +W F +PV+P  ++  
Sbjct: 1744 PAAGPRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVS-- 1801

Query: 112  DYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAMTYNPPHNDVHMMAKELNQ 171
             Y  II  PMD  T+  +L +  Y+  EEFAAD  L F N  T+N   ++V      + +
Sbjct: 1802 GYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRR 1861

Query: 172  IFDSKWKD 179
             F+S+W++
Sbjct: 1862 FFESRWEE 1869



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 22/81 (27%), Positives = 44/81 (54%), Gaps = 8/81 (9%)

Query: 357 KAQQKTLLEHGD-KGDPLKMQLEKERLERIQREERARIEAQIKTAEAAARARAEEELRQQ 415
           K + K   E G  K + LK ++++E+ E+++ +E+  +       +A    +A++ L  Q
Sbjct: 724 KKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEEV------TKAKPACKADKTLATQ 777

Query: 416 RE-KEREAARAAIEEMKRTVE 435
           R  +ER+  +  +EEMK+  E
Sbjct: 778 RRLEERQKQQMILEEMKKPTE 798


>GCN5_YEAST (Q03330) Histone acetyltransferase GCN5 (EC 2.3.1.48)
          Length = 439

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 34/95 (35%), Positives = 54/95 (56%), Gaps = 2/95 (2%)

Query: 86  ILKCLMSYPYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADV 145
           IL  L ++  +W F +PV+     +PDY+  I +PMDL T+  KL+ N Y  +E+F  D 
Sbjct: 339 ILTELQNHAAAWPFLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDA 396

Query: 146 RLTFSNAMTYNPPHNDVHMMAKELNQIFDSKWKDM 180
           RL F+N   YN  +   +  A  L + F++K K++
Sbjct: 397 RLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEI 431


>P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48)
          Length = 2414

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 33/83 (39%), Positives = 47/83 (55%)

Query: 94   PYSWVFNKPVDPVALNIPDYFAIIAKPMDLGTISSKLKKNVYSCVEEFAADVRLTFSNAM 153
            P S  F +PVDP  L IPDYF I+  PMDL TI  KL    Y    ++  D+ L F+NA 
Sbjct: 1070 PESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAW 1129

Query: 154  TYNPPHNDVHMMAKELNQIFDSK 176
             YN   + V+    +L+++F+ +
Sbjct: 1130 LYNRKTSRVYKYCSKLSEVFEQE 1152


>TF1A_MOUSE (Q64127) Transcription intermediary factor 1-alpha
            (TIF1-alpha) (Tripartite motif-containing protein 24)
          Length = 1051

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 8/141 (5%)

Query: 45   CNSAEKLFKPDSIKRGPPEGFEGQKEKRQ---KIDRKGSTQCAAILKCLMSYPYSWVFNK 101
            C     L KP+            +K K +   K+      +C  +L  L  +  S  F  
Sbjct: 868  CTFCRDLSKPEVDYDCDVPSHHSEKRKSEGLTKLTPIDKRKCERLLLFLYCHEMSLAFQ- 926

Query: 102  PVDPVALNIPDYFAIIAKPMDLGTISSKLKKN--VYSCVEEFAADVRLTFSNAMTYNPPH 159
              DPV L +PDY+ II  PMDL TI  +L+++  +Y+  E+F AD RL F N   +N P 
Sbjct: 927  --DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYCMYTKPEDFVADFRLIFQNCAEFNEPD 984

Query: 160  NDVHMMAKELNQIFDSKWKDM 180
            ++V     +L   F+   K++
Sbjct: 985  SEVANAGIKLESYFEELLKNL 1005


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.313    0.130    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,711,646
Number of Sequences: 164201
Number of extensions: 2541941
Number of successful extensions: 13054
Number of sequences better than 10.0: 568
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 420
Number of HSP's that attempted gapping in prelim test: 10286
Number of HSP's gapped (non-prelim): 1981
length of query: 510
length of database: 59,974,054
effective HSP length: 115
effective length of query: 395
effective length of database: 41,090,939
effective search space: 16230920905
effective search space used: 16230920905
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)