BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0214.3
(605 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
USO1_YEAST (P25386) Intracellular protein transport protein USO1 55 5e-07
RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase 50 2e-05
MYSJ_DICDI (P54697) Myosin IJ heavy chain 50 2e-05
MLP1_YEAST (Q02455) MLP1 protein (Myosin-like protein 1) 47 1e-04
FAU_DROME (Q9VGX3) Anoxia up-regulated protein 47 1e-04
SMC_METJA (Q59037) Chromosome partition protein smc homolog 47 2e-04
MYH3_RAT (P12847) Myosin heavy chain, fast skeletal muscle, embr... 47 2e-04
MYSA_DROME (P05661) Myosin heavy chain, muscle 46 3e-04
RA50_YEAST (P12753) DNA repair protein RAD50 (153 kDa protein) 45 4e-04
MYSC_CHICK (P29616) Myosin heavy chain, cardiac muscle isoform (... 45 4e-04
MYH4_HUMAN (Q9Y623) Myosin heavy chain, skeletal muscle, fetal (... 45 4e-04
MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle 45 5e-04
MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper prote... 45 5e-04
YA8D_SCHPO (Q09778) Hypothetical protein C22F3.13 in chromosome I 45 7e-04
MYSP_SCHJA (Q05870) Paramyosin (Antigen Sj97) 45 7e-04
DESP_HUMAN (P15924) Desmoplakin (DP) (250/210 kDa paraneoplastic... 45 7e-04
MYSS_CHICK (P13538) Myosin heavy chain, skeletal muscle, adult 44 0.001
IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B ... 44 0.001
SMC3_RAT (P97690) Structural maintenance of chromosome 3 (Chondr... 44 0.002
SMC3_MOUSE (Q9CW03) Structural maintenance of chromosome 3 (Chon... 44 0.002
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 55.1 bits (131), Expect = 5e-07
Identities = 78/327 (23%), Positives = 137/327 (41%), Gaps = 39/327 (11%)
Query: 277 EQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKDASQPSMEKFM--M 334
E+++++EK K+ S ESN + K + + + S+ S E+ + +
Sbjct: 1490 EEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNL 1549
Query: 335 KNNPQHLAHQSGSSSAPPPTWKSVL----KEFEEL-TSEEVTSLWDSKIDFNALVETNLV 389
++ L + S KS L K EL T ++ + KI NA E N V
Sbjct: 1550 QHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINA--EENTV 1607
Query: 390 FKADQEKIKRIGLKEACQAIMTKGLEIAAI-SKMVDLETAGFDGINSAKQLEEKER--EI 446
K+ E I+R LK+ I + E + S++ +LE D Q E+ER E+
Sbjct: 1608 LKSKLEDIER-ELKDKQAEIKSNQEEKELLTSRLKELEQE-LDSTQQKAQKSEEERRAEV 1665
Query: 447 LKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELN 506
K + LD + E K DL + + K+ + + T + E+ K E+ L
Sbjct: 1666 RKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKELDNLK 1725
Query: 507 SANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSINLAGSNPYARIV 566
+ NS+LK N SEI +L + D L+ +K + ++ L ++S
Sbjct: 1726 AENSKLKEANED-RSEIDDLMLLVTD-LDEKNAKYRSKLKDLGVEIS------------- 1770
Query: 567 DGKLINPDTGDEEEEEEYEGDKNEEDG 593
+EE++E + +++EE+G
Sbjct: 1771 ----------SDEEDDEEDDEEDEEEG 1787
Score = 44.3 bits (103), Expect = 0.001
Identities = 49/234 (20%), Positives = 102/234 (42%), Gaps = 22/234 (9%)
Query: 334 MKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDFNALV-----ETNL 388
M ++ + GS K + + E+ E ++ SK ++ + + +
Sbjct: 1006 MSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLET 1065
Query: 389 VFKADQEKIKRIG----LKEACQAIMT--KGLEIAAISKMVDLETAGFDGINSAKQLEEK 442
A+ E + +I +E +A + K L+ +K+ E A + + + L+E+
Sbjct: 1066 ATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEE 1125
Query: 443 ----EREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKS 498
E+E + K + L ++ + EK+ DLA + LKK+ E ++ ++ E+ +
Sbjct: 1126 KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQ---LKKYEEQIANKERQYNEEISQL 1182
Query: 499 QAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQV 552
EIT N +K +N +L E+ +K++ +Q + K +I LN Q+
Sbjct: 1183 NDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQ----SNLKKSEIDALNLQI 1232
Score = 40.4 bits (93), Expect = 0.013
Identities = 63/358 (17%), Positives = 143/358 (39%), Gaps = 49/358 (13%)
Query: 254 NKLGEYVAKMTRLSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKK---- 309
NK +Y ++++L+D+ I ++E ++ ++K + + + A S S +SN + +
Sbjct: 1170 NKERQYNEEISQLNDE-ITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDAL 1228
Query: 310 -------KKRNETPEPTKGKDASQPSMEKFMMKN----------NPQHLAHQSGSSSAPP 352
KK+NET E + + E +K L + +S
Sbjct: 1229 NLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKN 1288
Query: 353 PTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTK 412
+ + KE E++ E + KI + + + + ++ R+ K + +
Sbjct: 1289 SKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLK-KTSSEERKNA 1347
Query: 413 GLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLAL 472
++ + + ++ F EKER++L ++ + S K++ + + L
Sbjct: 1348 EEQLEKLKNEIQIKNQAF----------EKERKLLNEGSSTITQEYSEKINTLEDELIRL 1397
Query: 473 ENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILD 532
+NE ++K E+ +++E+ +++ +N EL E + I L++ IL
Sbjct: 1398 QNE------------NELKAKEIDNTRSELEKVSLSNDELLEEK---QNTIKSLQDEILS 1442
Query: 533 QLEAGFSKAKEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEGDKNE 590
+ ++ E++L + +L R + G ++ EEE +K E
Sbjct: 1443 YKDK-ITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAE 1499
Score = 37.0 bits (84), Expect = 0.15
Identities = 63/313 (20%), Positives = 120/313 (38%), Gaps = 44/313 (14%)
Query: 246 EFLNAHYENKLGEYVAKMTR-------LSDDDILRFRREQQAAREKRNPAKTLIDADASH 298
E + EN+L TR LS+D++L EK+N K+L D S+
Sbjct: 1393 ELIRLQNENELKAKEIDNTRSELEKVSLSNDELLE---------EKQNTIKSLQDEILSY 1443
Query: 299 SGTESNRPQK--------KKKRNETPEPTKGKDASQPSMEKFMMKNNPQHLAHQSGSSSA 350
+ +K K+ E + S+ +E+ + K L +S A
Sbjct: 1444 KDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKK-----LEEESSKEKA 1498
Query: 351 PPPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVET-NLVFKADQEKIKRIGLKEA--CQ 407
K ++K+ E T L S E K+ +E IK + +++
Sbjct: 1499 ELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLIS 1558
Query: 408 AIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKAT------MKLLDSSNK 461
I +I + + +E + + KQ +E +++ A KL D +
Sbjct: 1559 RINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERE 1618
Query: 462 VSEKKAADLALENE------RLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNE 515
+ +K+A + + E RLK+ + L +TQ+ + + +AE+ + S+L +
Sbjct: 1619 LKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEK 1678
Query: 516 NSKLHSEISELKN 528
L ++ ++L N
Sbjct: 1679 AMLLETKYNDLVN 1691
>RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase
Length = 864
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/172 (27%), Positives = 76/172 (43%), Gaps = 30/172 (17%)
Query: 378 IDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVD------------- 424
ID + + T +V + + +KI E Q IM K L++ I K++D
Sbjct: 118 IDKDIALSTIIVRQGELDKIL-----ENFQEIMGKILKLELIEKLIDSRGPIVEFRKNLE 172
Query: 425 -----LETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLA---LENER 476
L+ D N K +EEK +L++K + L+ K EK+ D+ E E+
Sbjct: 173 NKLRELDRIEQDYNNFKKTVEEKRARVLELKKDKEKLEDEIKNLEKRIKDIKDQFDEYEK 232
Query: 477 LKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKN 528
+ L+ T K+KEGEL + I EL + +L EI+EL+N
Sbjct: 233 KRNQYLKLTTTLKIKEGELNELNRSIEELRKQTENM----DQLEKEINELEN 280
Score = 33.5 bits (75), Expect = 1.6
Identities = 38/200 (19%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 358 VLKEFEELTS-----EEVTSLWDSK---IDFNALVETNLV----FKADQEKIKRIGLKEA 405
+L+ F+E+ E + L DS+ ++F +E L + D K+ ++
Sbjct: 137 ILENFQEIMGKILKLELIEKLIDSRGPIVEFRKNLENKLRELDRIEQDYNNFKKTVEEKR 196
Query: 406 CQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEK 465
+ + K + ++ +LE D + + E+K + LK+ T+K+ + +
Sbjct: 197 ARVLELKKDKEKLEDEIKNLEKRIKDIKDQFDEYEKKRNQYLKLTTTLKIKEGELNELNR 256
Query: 466 KAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISE 525
+L + E + + + ++ + ++ +L + E+ L +++E+ L EI E
Sbjct: 257 SIEELRKQTENMDQLEKEINELENLRNIKLKFEKYEV--LAKSHTEMSANVINLEKEIEE 314
Query: 526 LKNSI--LDQLEAGFSKAKE 543
+ +I ++LE + K KE
Sbjct: 315 YEKAIRRKEELEPKYLKYKE 334
Score = 32.3 bits (72), Expect = 3.7
Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 32/258 (12%)
Query: 355 WKSVLKEFEELTSE-----EVTSLWDSKIDFNALVETNLV-FKADQEKIKRIGLKEACQA 408
+K + ++ EEL + ++ S DSK++ +E + D +K+ L++ +
Sbjct: 332 YKELERKLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSNDIDKVN--SLEQKVEE 389
Query: 409 IMTKGLEIAA-ISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNK---VSE 464
K L + A ++K+ L + + IN+ Q+E + + + LD +K + E
Sbjct: 390 TRKKQLNLRAQLAKVESLISEKNEIINNISQVEGETCPVCG-----RPLDEEHKQKIIKE 444
Query: 465 KKAADLALE------NERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSK 518
K+ L LE E LKK L+ ++ + L ++A + +L E
Sbjct: 445 AKSYILQLELNKNELEEELKKITNELNKIER-EYRRLSNNKASYDNVMRQLKKLNEEIEN 503
Query: 519 LHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSINLAGSNPYARIVDGKLINPD---T 575
LHSEI LKN ++ K E++ L + S +D K + D
Sbjct: 504 LHSEIESLKN-----IDEEIKKINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDEMKK 558
Query: 576 GDEEEEEEYEGDKNEEDG 593
EE E+E G ++E G
Sbjct: 559 KKEEIEKEMRGLESELKG 576
>MYSJ_DICDI (P54697) Myosin IJ heavy chain
Length = 2245
Score = 49.7 bits (117), Expect = 2e-05
Identities = 80/408 (19%), Positives = 157/408 (37%), Gaps = 60/408 (14%)
Query: 216 EAIIKLPDDSLTPEE------------MVDCTFLSSIDLNLTEFLNAHYEN---KLGEYV 260
E +IKL + L EE + D I L LTE N + KL EY
Sbjct: 1217 EQLIKLSSEKLGSEEEAKKQINQLELELTDHKSKLQIQLQLTEQSNEKIKKLKGKLEEYQ 1276
Query: 261 AKMTRLSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTK 320
+ +L + + R ++ +Q+ +++N T + S S +K++ T + T
Sbjct: 1277 DEKKQLQQE-LERIKQSKQSVEDEKNSLITQLTTVKFESTQVSTNVSHQKEKITTLKSTI 1335
Query: 321 GKDASQPSMEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDF 380
+ + KN + + + KEF +L S++ S+I
Sbjct: 1336 EELNKSIGKLQAEQKNKDDEIRKIQFELNDQKQQFTRQTKEFSDLQSQQSIDRPKSEITI 1395
Query: 381 NALVETNLVFKADQEKIKRIGLKEA---CQAIMTKGLEIAAISKMVDLETAGFDGINSAK 437
++L TN K+D E++++ LK+ CQ D IN
Sbjct: 1396 HSLERTNETLKSDFERVQQ-SLKQQERDCQQYK--------------------DTIN--- 1431
Query: 438 QLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVK 497
+LE + +++ ++K + ++ V++++ ++ E+ LK+ + Q E EL +
Sbjct: 1432 RLENEVKQLTQLK---ERFENEFFVAKEQNSNQTQESVYLKEVTTQMQQNQSRIERELEE 1488
Query: 498 SQAEITELNSANSELKNENSKL--------------HSEISELKNSILDQLEAGFSKAKE 543
+ IT ++ ELK + ++L +E+ L+ L E G +K+
Sbjct: 1489 KKQHITRIDDERDELKKQLTQLQQQHEQSSTQLLLAQNELERLRKKELKYKERGHETSKQ 1548
Query: 544 QILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEGDKNEE 591
Q F S+ + ++ + D + D+ + E + E
Sbjct: 1549 QDQFNMEIQSLRITNNDQLKSLQDYEQEKKKLKDKLSSSKQEAQQQRE 1596
Score = 31.2 bits (69), Expect = 8.2
Identities = 38/159 (23%), Positives = 70/159 (43%), Gaps = 27/159 (16%)
Query: 395 EKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMK 454
E++ R + A + TK +I + + VD + G I + +++ +R ++++A +
Sbjct: 913 EQVHRERCENAAIILQTKIRQILS-KREVDKKLRGIILIQARWRMKLAKRVYIQLRAEAR 971
Query: 455 LL----DSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELNSANS 510
L + NK+ EK LE + + +EA Q E + VKS I+EL+S N
Sbjct: 972 SLRTVQEQKNKLQEK------LEELQWRLTSEAKRKQQL--EDQKVKSDTTISELSSNND 1023
Query: 511 --------------ELKNENSKLHSEISELKNSILDQLE 535
EL N N ++SE + + +Q +
Sbjct: 1024 HLELQLSEIQLKYQELDNSNQSSQLQLSECLSKLEEQTQ 1062
>MLP1_YEAST (Q02455) MLP1 protein (Myosin-like protein 1)
Length = 1875
Score = 47.0 bits (110), Expect = 1e-04
Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 14/227 (6%)
Query: 357 SVLKEFEEL--TSEEVTSLWDSKIDFNALVETNLVFKADQEKIK---RIGLKEACQAIMT 411
S +KE+++L T+ + +SK+D + TN + EK +I L + +
Sbjct: 921 SQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLN 980
Query: 412 KGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKA-ADL 470
L++ K ++ E A F S Q KE E +K + KL N + ++ A+
Sbjct: 981 NELDLQ--KKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLDQQTIYANT 1038
Query: 471 ALEN--ERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKN 528
A N + L+KHA+ +++E +L + ++ LN + +L+N + S K
Sbjct: 1039 AQNNYEQELQKHADVSKTISELRE-QLHTYKGQVKTLNLSRDQLENALKENEKSWSSQKE 1097
Query: 529 SILDQLEAGFSKAKE---QILFLNPQVSINLAGSNPYARIVDGKLIN 572
S+L+QL+ S+ ++ Q L Q+ I A +G +N
Sbjct: 1098 SLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVNNSTNGPGLN 1144
Score = 36.6 bits (83), Expect = 0.19
Identities = 39/171 (22%), Positives = 81/171 (46%), Gaps = 11/171 (6%)
Query: 431 DGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKV 490
D + +QL + E K+++ ++ L + E++ A+ + RL++ A+ T K+
Sbjct: 1288 DILEKHEQLSSSDYE--KLESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKL 1345
Query: 491 KEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSIL----DQLEAGFSKAKEQIL 546
+ L + ++ L A + L+N S+ ++ I EL+N+ + +QLEA K +E
Sbjct: 1346 SQDSLTE---QVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEA-IRKLQEDAE 1401
Query: 547 FLNPQVSINLAGS-NPYARIVDGKLINPDTGDEEEEEEYEGDKNEEDGNAN 596
+ ++ L S Y ++G T EE E++ + + + +AN
Sbjct: 1402 KASRELQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSAN 1452
Score = 35.4 bits (80), Expect = 0.43
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 18/127 (14%)
Query: 418 AISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERL 477
A K V+ T G G+N+ +ER+IL K T+ D+ + D+ L++ R
Sbjct: 1129 AADKEVNNSTNG-PGLNNILITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDART 1187
Query: 478 KKHAEALSATQKVKEGELVKSQAEITE-LNSAN----------SELKNENSK---LHSEI 523
K S +K +++ +I E LN N +EL+N N+K L SE+
Sbjct: 1188 KLDN---SRVEKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSEL 1244
Query: 524 SELKNSI 530
+LK ++
Sbjct: 1245 DKLKQNV 1251
Score = 31.6 bits (70), Expect = 6.3
Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 20/102 (19%)
Query: 438 QLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVK 497
QL+EK E+LK+ + ++K+ K+ KK ++L QK++ + +
Sbjct: 541 QLQEKNAELLKVVRNL-----ADKLESKE-----------KKSKQSL---QKIESETVNE 581
Query: 498 SQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFS 539
++ I L S +L++ +L E+ ELK S+ ++ +A +S
Sbjct: 582 AKEAIITLKSEKMDLESRIEELQKELEELKTSVPNE-DASYS 622
Score = 31.2 bits (69), Expect = 8.2
Identities = 44/208 (21%), Positives = 76/208 (36%), Gaps = 35/208 (16%)
Query: 359 LKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAA 418
L++ + + V L D + FN L NL +++K LK+ + T+ +
Sbjct: 32 LEQVKSFDGDVVKHLNDKLLQFNELKSENLKVTVSFDELKASSLKKI-DGLKTEMENVIR 90
Query: 419 ISKMVDLET----AGFDGINSAKQLEEKEREILKMKA----------------TMKLLDS 458
+ + E F+ + + K E E +K K T+K+LD
Sbjct: 91 ENDKIRKERNDTFVKFESVENEKMKLSSELEFVKRKLDDLTEEKKETQSNQQRTLKILDE 150
Query: 459 SNKVSEKKAADLALENERLKKHAEALSATQKVKEG----------ELVKSQAEITELNSA 508
K E + N KK + + ++G EL + E+T L S
Sbjct: 151 RLKEIELVRVENNRSNSECKKLRSTIMDLETKQQGYITNDLNSRTELERKTQELTLLQSN 210
Query: 509 N----SELKNENSKLHSEISELKNSILD 532
N EL+++N + S + ILD
Sbjct: 211 NDWLEKELRSKNEQYLSYRQKTDKVILD 238
>FAU_DROME (Q9VGX3) Anoxia up-regulated protein
Length = 619
Score = 47.0 bits (110), Expect = 1e-04
Identities = 72/320 (22%), Positives = 121/320 (37%), Gaps = 54/320 (16%)
Query: 275 RREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKDASQPSMEKFMM 334
RRE++A +E+R+ + A+ ++ + ++ + E + A+Q + E+
Sbjct: 343 RREERALKEERDRLTAEAEKQAA---AKAKKAAEEAAKIAAEEALLAEAAAQKAAEEAKA 399
Query: 335 KNNPQHLAHQSGSSS--APPPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKA 392
+ A ++ + A + V +E + +EE L E KA
Sbjct: 400 LKAAEDAAQKAAEEARLAEEAAAQKVAEEAAQKAAEEAR-----------LAEEAAAQKA 448
Query: 393 DQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKAT 452
+E ++ + A +A L A K E A + A+ EE A
Sbjct: 449 AEEAAQKAAEEAALKAAEEARLAEEAAQKAA--EEAALKAVEEARAAEE---------AA 497
Query: 453 MKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSEL 512
K + + E A L E ++ E L+ +K EGEL + AE+ E+ SEL
Sbjct: 498 QKAAEEARVAEE---ARLEEEQRVREQELERLAEIEKESEGELARQAAELAEIARQESEL 554
Query: 513 ---------KNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSINLAGSNPYA 563
KNEN + E + +Q E I+ L V+ G N Y
Sbjct: 555 AAQELQAIQKNENETSEPVVEEPVTPVEEQ---------EPIIELGSNVT--PTGGNSYE 603
Query: 564 RIVDGKLINPDTGDEEEEEE 583
+D + + DEEEEEE
Sbjct: 604 EDLDAE----EEEDEEEEEE 619
>SMC_METJA (Q59037) Chromosome partition protein smc homolog
Length = 1169
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/279 (22%), Positives = 130/279 (46%), Gaps = 24/279 (8%)
Query: 271 ILRFRREQQAAREKRNPAKTLIDA-DASHSGTESNRPQKKKKRNETPEPTKGKDASQPSM 329
I F +++ A E+ A+ LI+ D S E+N + KK++ + + K + + +
Sbjct: 171 IAEFDEKKKKAEEELKKARELIEMIDIRISEVENNLKKLKKEKEDAEKYIKLNEELKAAK 230
Query: 330 EKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDF-NALVETNL 388
++K + + ++ +K EEL +E ++ + + ++ N + N
Sbjct: 231 YALILK--------KVSYLNVLLENIQNDIKNLEELKNEFLSKVREIDVEIENLKLRLNN 282
Query: 389 VFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVD-----LETAGFDGINSAKQLEEKE 443
+ EK L E ++I +EI K++D L+ + N K+++E +
Sbjct: 283 IINELNEKGNEEVL-ELHKSIKELEVEIENDKKVLDSSINELKKVEVEIENKKKEIKETQ 341
Query: 444 REILKMKATMKLLDSSNKVSEKKAADLALENERLKKH-AEALSATQKVKEG------ELV 496
++I++ + ++ + K E+K +L E ERLK+ AE+ S + +KE E+
Sbjct: 342 KKIIENRDSIIEKEQQIKEIEEKIKNLNYEKERLKEAIAESESIIKHLKESEMEIADEIA 401
Query: 497 KSQAEITELNSANSELKNENSKLHSEISELKNSILDQLE 535
K+Q E+ L ++L N ++ + EI E N ++ +L+
Sbjct: 402 KNQNELYRLKKELNDLDNLINRKNFEI-EKNNEMIKKLK 439
>MYH3_RAT (P12847) Myosin heavy chain, fast skeletal muscle, embryonic
Length = 1940
Score = 46.6 bits (109), Expect = 2e-04
Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 18/229 (7%)
Query: 360 KEFEELTS--EEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIA 417
+E EEL+ EE + ++I+ N E + K ++ + EA A + K +
Sbjct: 1142 RELEELSERLEEAGGVTSTQIELNKKREAEFL-KLRRDLEEATLQHEATVATLRKKHADS 1200
Query: 418 AISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERL 477
A + D + KQ EKE+ K++ L S VS+ KA L
Sbjct: 1201 AAELAEQI-----DNLQRVKQKLEKEKSEFKLEID-DLSSSVESVSKSKA--------NL 1246
Query: 478 KKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAG 537
+K L G+ ++Q ++EL + S L+ E +L ++ E K SI+ QL
Sbjct: 1247 EKICRTLEDQLSEARGKNEETQRSLSELTTQKSRLQTEAGELSRQLEE-KESIVSQLSRS 1305
Query: 538 FSKAKEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEG 586
+QI L Q+ N A + + D E+ EEE EG
Sbjct: 1306 KQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG 1354
Score = 34.3 bits (77), Expect = 0.97
Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 15/122 (12%)
Query: 437 KQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKE---G 493
K++ + E K K + ++ K E+K L E L+ +A S E
Sbjct: 848 KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCD 907
Query: 494 ELVKSQ-------AEITEL----NSANSELKNENSKLHSEISELKNSILDQLEAGFSKAK 542
+L+K++ E+TE N+EL + KL E SELK I D LE +K +
Sbjct: 908 QLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI-DDLELTLAKVE 966
Query: 543 EQ 544
++
Sbjct: 967 KE 968
>MYSA_DROME (P05661) Myosin heavy chain, muscle
Length = 1962
Score = 45.8 bits (107), Expect = 3e-04
Identities = 67/306 (21%), Positives = 132/306 (42%), Gaps = 19/306 (6%)
Query: 253 ENKLGEYVAKMTRLSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKR 312
EN+L + ++T+ D F+++++A +E K + D + + E ++ K +
Sbjct: 915 ENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDHQI 974
Query: 313 NETPEPTKGKDA--SQPSMEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEV 370
+ +D ++ + EK M Q + ++ V + E+ E
Sbjct: 975 RNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDELE 1034
Query: 371 TSLWDSKIDFNALVETNLVFKAD----QEKIKRI--GLKEACQAIMTKGLEIAAISKMVD 424
SL K + ++ + D QE + + KE Q I K E+++I+ ++
Sbjct: 1035 DSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLE 1094
Query: 425 LETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALE----NERLKKH 480
E + +Q++E + I +++ ++ + +EK+ ADLA E ERL++
Sbjct: 1095 DEQVVV--LKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEA 1152
Query: 481 AEALSA---TQKVKEGELVKSQAEITELN-SANSELKNENSKLHSEISELKNSILDQLEA 536
A SA K +E EL K + ++ E N S L N K + ++E+ + DQL
Sbjct: 1153 GGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQV-DQLNK 1211
Query: 537 GFSKAK 542
+KA+
Sbjct: 1212 LKAKAE 1217
>RA50_YEAST (P12753) DNA repair protein RAD50 (153 kDa protein)
Length = 1312
Score = 45.4 bits (106), Expect = 4e-04
Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 420 SKMVDLETAGFDGINSA-KQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLK 478
+++VD E GFD + + K+LE + ++L++K + L + ++K AD E + LK
Sbjct: 967 NEVVDFEAKGFDELQTTIKELELNKAQMLELKEQLDLKSNEVNEEKRKLADSNNEEKNLK 1026
Query: 479 KHAEALSATQKVK--------------EGELVKSQAEITELNSANSELKNENSKLHSEIS 524
++ E + +++ E E K Q E L + +L +EN+ E+
Sbjct: 1027 QNLELIELKSQLQHIESEISRLDVQNAEAERDKYQEESLRLRTRFEKLSSENAGKLGEMK 1086
Query: 525 ELKNSI 530
+L+N I
Sbjct: 1087 QLQNQI 1092
Score = 32.0 bits (71), Expect = 4.8
Identities = 39/183 (21%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Query: 372 SLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFD 431
++++ +DF A L Q IK + L +A + + L++ S V+ E
Sbjct: 964 TIYNEVVDFEAKGFDEL-----QTTIKELELNKAQMLELKEQLDLK--SNEVNEEKRKLA 1016
Query: 432 GINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLAL-----ENERLKKHAEALSA 486
N+ ++ ++ E++++K+ ++ ++S + + A+ E+ RL+ E LS+
Sbjct: 1017 DSNNEEKNLKQNLELIELKSQLQHIESEISRLDVQNAEAERDKYQEESLRLRTRFEKLSS 1076
Query: 487 TQKVKEGELVKSQAEITEL-NSANSELKNENSKLHSEISEL--KNSILDQLEAGFSKAKE 543
K GE+ + Q +I L + ++ K+ H E EL ++ + D ++ +SKA +
Sbjct: 1077 ENAGKLGEMKQLQNQIDSLTHQLRTDYKDIEKNYHKEWVELQTRSFVTDDIDV-YSKALD 1135
Query: 544 QIL 546
+
Sbjct: 1136 SAI 1138
>MYSC_CHICK (P29616) Myosin heavy chain, cardiac muscle isoform
(Fragment)
Length = 1102
Score = 45.4 bits (106), Expect = 4e-04
Identities = 90/374 (24%), Positives = 154/374 (41%), Gaps = 61/374 (16%)
Query: 252 YENKLGEYVAK---MTRLSDDDILRFRREQQAARE--KRNPAKTLIDADASHSGTESNRP 306
YE+ L E K MTRL +D + + Q E ++ K + + S G S
Sbjct: 418 YEDHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEFVRQLEEKESLISQLSR-GKTSFTQ 476
Query: 307 QKKKKRNETPEPTKGKDASQPSMEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELT 366
Q ++ R + E TK K+A +++ +++ L Q K+ L+
Sbjct: 477 QIEELRRQLEEETKSKNALAHALQA--ARHDCDLLREQYEEEQEA----KAELQRALSKG 530
Query: 367 SEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISK----- 421
+ EV W +K + +A+ T + A ++ + R L+EA +AI + +++ K
Sbjct: 531 NAEVAQ-WRTKYETDAIQRTEELEDAKKKLLAR--LQEAEEAIEAANAKCSSLEKAKHRL 587
Query: 422 -------MVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALEN 474
M+DLE A ++A L++K+R K+ + D K E +A E
Sbjct: 588 QNEQEDMMIDLEKAN----SAAASLDKKQRGFDKI-----INDWKQKYEESQA-----EL 633
Query: 475 ERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSI---- 530
E +K A +LS EL K + E LK EN L EIS+L N I
Sbjct: 634 EASQKEARSLST-------ELFKLKNAYEETLDHLETLKRENKNLQEEISDLTNQISEGN 686
Query: 531 --LDQLEAGFSKAKEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYE--- 585
L ++E K K+Q+ +V + L + + K + + + ++E
Sbjct: 687 KNLHEIE----KVKKQVEQEKSEVQLALEEAEGALEHEESKTLRFQLELSQLKADFERKL 742
Query: 586 GDKNEEDGNANNNE 599
+K+EE N N+
Sbjct: 743 AEKDEEMQNIRRNQ 756
Score = 41.6 bits (96), Expect = 0.006
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 437 KQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGE-- 494
K++ + E LK+K ++ ++ K E+K L E L +A T E
Sbjct: 13 KEMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLLLQLQAEQDTLADAEERCD 72
Query: 495 -LVKS----QAEITELNSA-------NSELKNENSKLHSEISELKNSILDQLEAGFSKAK 542
L+KS +A++ EL NSEL ++ KL E SELK I D LE +K +
Sbjct: 73 LLIKSKIQLEAKVKELTERVEDEEEMNSELTSKKRKLEDECSELKKDI-DDLEITLAKVE 131
Query: 543 EQ 544
++
Sbjct: 132 KE 133
Score = 40.4 bits (93), Expect = 0.013
Identities = 43/164 (26%), Positives = 66/164 (40%), Gaps = 28/164 (17%)
Query: 431 DGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERL---KKHAEALSAT 487
D + KQ EKE+ LKM+ DL E+ K +AE L T
Sbjct: 374 DNLQRVKQKLEKEKSELKMEVD----------------DLTANMEQTVKGKANAEKLWGT 417
Query: 488 QKVKEGELVKSQAEITELNSANSELKNENSKLHSEISEL------KNSILDQLEAGFSKA 541
E L +++ ++ E+ ++L + +KL SE E K S++ QL G +
Sbjct: 418 Y---EDHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEFVRQLEEKESLISQLSRGKTSF 474
Query: 542 KEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYE 585
+QI L Q+ N A + + D E+ EEE E
Sbjct: 475 TQQIEELRRQLEEETKSKNALAHALQAARHDCDLLREQYEEEQE 518
Score = 39.3 bits (90), Expect = 0.030
Identities = 69/329 (20%), Positives = 130/329 (38%), Gaps = 47/329 (14%)
Query: 283 EKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKDASQPSMEKFMMKNNPQHLA 342
EK N A +D N ++K + ++ K+A S E F +KN +
Sbjct: 599 EKANSAAASLDKKQRGFDKIINDWKQKYEESQAELEASQKEARSLSTELFKLKNAYEETL 658
Query: 343 HQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDFNA-LVETNLVFK-ADQEKIK-R 399
LK + EE++ L + + N L E V K +QEK + +
Sbjct: 659 DHL-----------ETLKRENKNLQEEISDLTNQISEGNKNLHEIEKVKKQVEQEKSEVQ 707
Query: 400 IGLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMK----- 454
+ L+EA A+ + + + A F+ ++L EK+ E+ ++ +
Sbjct: 708 LALEEAEGALEHEESKTLRFQLELSQLKADFE-----RKLAEKDEEMQNIRRNQQRTIDS 762
Query: 455 ---LLDSS----------NKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAE 501
LDS K E ++ ++ +HA + + + + ++ + Q +
Sbjct: 763 LQSTLDSEARSRNEAIRLKKKMEGDLNEMEIQLSHANRHAAEATKSARGLQTQIKELQVQ 822
Query: 502 ITELNSANSELKNE-------NSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSI 554
+ +L N +LK + N+ L SE+ EL+ ++LDQ E A+ ++L +V
Sbjct: 823 LDDLGHLNEDLKEQLAVSDRRNNLLQSELDELR-ALLDQTERARKLAEHELLEATERV-- 879
Query: 555 NLAGSNPYARIVDGKLINPDTGDEEEEEE 583
NL + + I K + D + E E
Sbjct: 880 NLLHTQNTSLINQKKKLEGDISQMQNEVE 908
>MYH4_HUMAN (Q9Y623) Myosin heavy chain, skeletal muscle, fetal
(Myosin heavy chain IIb) (MyHC-IIb)
Length = 1939
Score = 45.4 bits (106), Expect = 4e-04
Identities = 77/335 (22%), Positives = 133/335 (38%), Gaps = 37/335 (11%)
Query: 282 REKRNPAKTLIDADASHSGTESNRPQ---KKKKRNETPEPTKGKDASQPSMEKFMMKNNP 338
R KR L A S TE+++ Q K KK+ +GK + ++ + K
Sbjct: 1054 RAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIK 1113
Query: 339 QHLAH----------QSGSSSAPPPTWKSVLKEFEELTS--EEVTSLWDSKIDFNALVET 386
+ A + S + + +E EE++ EE ++I+ N E
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREA 1173
Query: 387 NLVFKADQEKIKRIGLK-EACQAIMTK--GLEIAAISKMVDLETAGFDGINSAKQLEEKE 443
F+ + ++ L+ EA A + K +A + K +D + KQ EKE
Sbjct: 1174 E--FQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQID-------SLQRVKQKLEKE 1224
Query: 444 REILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEIT 503
+ LKM+ L + VS+ KA E++ + E + K KE E Q I
Sbjct: 1225 KSELKMEIN-DLASNMETVSKAKA-----NFEKMCRTLEDQLSEIKTKEEE---QQRLIN 1275
Query: 504 ELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSINLAGSNPYA 563
EL++ + L E+ + ++ E K++++ QL G +QI L Q+ + A
Sbjct: 1276 ELSAQKARLHTESGEFSRQLDE-KDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLA 1334
Query: 564 RIVDGKLINPDTGDEEEEEEYEGDKNEEDGNANNN 598
+ + D E+ EEE E + G + N
Sbjct: 1335 HALQSARHDCDLLREQYEEEQEAKAELQRGMSKAN 1369
Score = 36.6 bits (83), Expect = 0.19
Identities = 33/122 (27%), Positives = 61/122 (49%), Gaps = 16/122 (13%)
Query: 434 NSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEG 493
N ++ E+ + E+ K +A K L+ ++ DL L+ ++ A+AL+ ++ +
Sbjct: 855 NMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ---VQAEADALADAEE-RCD 910
Query: 494 ELVKSQA-------EITEL----NSANSELKNENSKLHSEISELKNSILDQLEAGFSKAK 542
+L+K++ E+TE N+EL + KL E SELK I D LE +K +
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI-DDLELTLAKVE 969
Query: 543 EQ 544
++
Sbjct: 970 KE 971
Score = 35.4 bits (80), Expect = 0.43
Identities = 67/355 (18%), Positives = 134/355 (36%), Gaps = 44/355 (12%)
Query: 262 KMTRLSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNR--PQKKKKRNETPEPT 319
KM R +D + + +++ + N + A + TES Q +K + +
Sbjct: 1251 KMCRTLEDQLSEIKTKEEEQQRLINE----LSAQKARLHTESGEFSRQLDEKDAMVSQLS 1306
Query: 320 KGKDASQPSMEKFMMKNNPQH-----LAHQSGSSSAPPPTWKSVLKEFEELTSE------ 368
+GK A +E+ + + LAH S+ + +E +E +E
Sbjct: 1307 RGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMS 1366
Query: 369 ---EVTSLWDSKIDFNALVETNLVFKADQEKIKRI-GLKEACQAIMTKGLEIAAISKMVD 424
+ W +K + +A+ T + +A ++ +R+ +E +A+ +K + + +
Sbjct: 1367 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQ 1426
Query: 425 LETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEAL 484
E +E+ ++ + A LD + +K A+ + E + EA
Sbjct: 1427 NE------------VEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEAS 1474
Query: 485 SATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAG-----FS 539
+ EL K + E LK EN L EIS+L I E G
Sbjct: 1475 QKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQI---AEGGKHIHELE 1531
Query: 540 KAKEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYE---GDKNEE 591
K K+Q+ ++ +L + +GK++ + + E + +K+EE
Sbjct: 1532 KVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
Score = 33.5 bits (75), Expect = 1.6
Identities = 61/305 (20%), Positives = 124/305 (40%), Gaps = 47/305 (15%)
Query: 268 DDDILR--FRREQQAARE------KRNPA----KTLIDADASHSGTESNRPQKK--KKRN 313
D D+LR + EQ+A E K N +T + DA E +KK ++
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1402
Query: 314 ETPEPTKGKDASQPSMEKFM--MKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVT 371
+ E + ++ S+EK ++N + L S+A + F+++ +E
Sbjct: 1403 DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAE--- 1459
Query: 372 SLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFD 431
W K + ET +A Q++ + + + + K+ + D
Sbjct: 1460 --WKQKYE-----ETQAELEASQKESRSLSTE---------------LFKVKNAYEESLD 1497
Query: 432 GINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENER--LKKHAEALSATQK 489
+ + K+ E K + T ++ + + E + L++E+ L+ E A+ +
Sbjct: 1498 HLETLKR-ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556
Query: 490 VKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLN 549
+EG++++ Q E LN SE+ + ++ E+ +LK + L +E+ S +I N
Sbjct: 1557 HEEGKILRIQLE---LNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRN 1613
Query: 550 PQVSI 554
+ I
Sbjct: 1614 DALRI 1618
>MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle
Length = 1935
Score = 45.1 bits (105), Expect = 5e-04
Identities = 53/241 (21%), Positives = 104/241 (42%), Gaps = 18/241 (7%)
Query: 360 KEFEELTS--EEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIA 417
+E EE++ EE ++I+ N E F+ + ++ L+ A + +
Sbjct: 1142 RELEEISERLEEAGGATAAQIEMNKKREAE--FQKMRRDLEESTLQHEATAAALRKEQAD 1199
Query: 418 AISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERL 477
+++++ + D + KQ EKE+ KM+ + L S+ + K A+L E++
Sbjct: 1200 SVAELGEQ----IDNLQRVKQKLEKEKSEYKME--IDDLTSNMEAVAKAKANL----EKM 1249
Query: 478 KKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAG 537
+ E + K K E V+ ++ ++N+ + L+ EN + ++ E K +++ QL G
Sbjct: 1250 CRTLEDQLSEIKTKSDENVR---QLNDMNAQRARLQTENGEFSRQLEE-KEALVSQLTRG 1305
Query: 538 FSKAKEQILFLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEGDKNEEDGNANN 597
+QI L + + N A V + D E+ EEE E + G +
Sbjct: 1306 KQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKAELQRGMSKA 1365
Query: 598 N 598
N
Sbjct: 1366 N 1366
Score = 37.4 bits (85), Expect = 0.11
Identities = 65/297 (21%), Positives = 117/297 (38%), Gaps = 55/297 (18%)
Query: 262 KMTRLSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNET--PEPT 319
KM R +D + + + + N ++A + TE+ ++ + E + T
Sbjct: 1248 KMCRTLEDQLSEIKTKSDENVRQLND----MNAQRARLQTENGEFSRQLEEKEALVSQLT 1303
Query: 320 KGKDASQPSMEKFMMKNNPQ-----HLAHQSGSSSAPPPTWKSVLKEFEELTSE------ 368
+GK A +E+ + LAH S+ + +E +E +E
Sbjct: 1304 RGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQYEEEQEAKAELQRGMS 1363
Query: 369 ---EVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISK---- 421
+ W +K + +A+ T + +A ++ +R L++A ++I + A++ K
Sbjct: 1364 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR--LQDAEESIEAVNSKCASLEKTKQR 1421
Query: 422 --------MVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALE 473
M+D+E A + A L++K+R K+ A K K E +A E
Sbjct: 1422 LQGEVEDLMIDVERAN----SLAANLDKKQRNFDKVLAEWK-----QKYEESQA-----E 1467
Query: 474 NERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSI 530
E +K A +LS EL K + E LK EN L EIS+L +
Sbjct: 1468 LEGAQKEARSLST-------ELFKMKNSYEEALDHLETLKRENKNLQQEISDLTEQL 1517
Score = 35.8 bits (81), Expect = 0.33
Identities = 31/111 (27%), Positives = 49/111 (43%), Gaps = 17/111 (15%)
Query: 437 KQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVK---EG 493
K+LEEK +L+ K ++L + E+E L E K K E
Sbjct: 872 KELEEKMVSLLQEKNDLQL-------------QVTAESENLSDAEERCEGLIKSKIQLEA 918
Query: 494 ELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQ 544
+L ++ + + N+EL + KL E SELK I D LE +K +++
Sbjct: 919 KLKETNERLEDEEEINAELTAKKRKLEDECSELKKDI-DDLELTLAKVEKE 968
Score = 31.6 bits (70), Expect = 6.3
Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 11/143 (7%)
Query: 402 LKEACQAIMTKGLEIAAISKMVD-LETAGFDGINSAKQLEEKEREILKMKATMKLLDSSN 460
+K + + ++ IA ++K L+ A ++ + E+K + K K +
Sbjct: 976 VKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKL------- 1028
Query: 461 KVSEKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLH 520
E++ DL E+ KK L ++ EG+L +Q I +L + + + K
Sbjct: 1029 ---EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENEKQQSDEKIKKKD 1085
Query: 521 SEISELKNSILDQLEAGFSKAKE 543
EIS+L + I D+ G K+
Sbjct: 1086 FEISQLLSKIEDEQSLGAQLQKK 1108
Score = 31.2 bits (69), Expect = 8.2
Identities = 76/352 (21%), Positives = 141/352 (39%), Gaps = 61/352 (17%)
Query: 307 QKKKKRNETPEPTKGKDASQPSM-----EKFMMKNNPQHLAHQSGS---SSAPPPTWKSV 358
+K+K +E E K D + ++ EK +N ++L + S S A K
Sbjct: 940 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKA 999
Query: 359 LKEFEELTSEEV--------------TSLWDSKIDFNALVETNLVFKADQEKIKRI---G 401
L+E + T +++ T L D +E + D E+ KR
Sbjct: 1000 LQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1059
Query: 402 LKEACQAIMT--------------KGLEIAAI-SKMVDLETAGFDGINSAKQLEEKEREI 446
LK A ++IM K EI+ + SK+ D ++ G K+++E + I
Sbjct: 1060 LKLAQESIMDLENEKQQSDEKIKKKDFEISQLLSKIEDEQSLG---AQLQKKIKELQARI 1116
Query: 447 LKMKATMKLLDSSNKVSEKKAADLALE----NERLKKHAEALSA---TQKVKEGELVKSQ 499
+++ ++ ++ EK+ ADL+ E +ERL++ A +A K +E E K +
Sbjct: 1117 EELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMR 1176
Query: 500 AEITEL----NSANSELKNENSKLHSEISELKNS---ILDQLEAGFSKAKEQILFLNPQ- 551
++ E + + L+ E + +E+ E ++ + +LE S+ K +I L
Sbjct: 1177 RDLEESTLQHEATAAALRKEQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLTSNM 1236
Query: 552 --VSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEGDKNEEDGNANNNEGE 601
V+ A R ++ +L T +E + D N + GE
Sbjct: 1237 EAVAKAKANLEKMCRTLEDQLSEIKTKSDENVRQL-NDMNAQRARLQTENGE 1287
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein)
(Myosin II) (Non-muscle MHC)
Length = 2057
Score = 45.1 bits (105), Expect = 5e-04
Identities = 70/293 (23%), Positives = 117/293 (39%), Gaps = 31/293 (10%)
Query: 262 KMTRLSDDDILRFRREQQAAREKRNPAKTLIDA-------DASHSGTESNRPQKKKKRNE 314
K L+ D+ E++AAR+K K +DA D + + ++ + K+KK E
Sbjct: 1030 KKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLE 1089
Query: 315 TPEPTKGKDASQPSMEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLW 374
+ D SQ E+ + +HLA A + E EE ++
Sbjct: 1090 ----ERANDLSQTLAEE---EEKAKHLAKLKAKHEA-------TITELEERLHKDQQQRQ 1135
Query: 375 DSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGIN 434
+S +ET + +Q +R+ + E + + E+ +D E+A
Sbjct: 1136 ESDRS-KRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESA--TKAT 1192
Query: 435 SAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKH-AEALSATQKVKEG 493
+ K E E ++ +++ ++ ++ +EK DL+ E E LK ++L T +E
Sbjct: 1193 AQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQEL 1252
Query: 494 ELVKSQAEITELNSANSELKNENSKL----HSEISELKNSILDQLEAGFSKAK 542
+ Q T S E N L H EL NSI DQLE KAK
Sbjct: 1253 RSKREQELATLKKSLEEETVNHEGVLADMRHKHSQEL-NSINDQLE-NLRKAK 1303
Score = 35.8 bits (81), Expect = 0.33
Identities = 64/344 (18%), Positives = 147/344 (42%), Gaps = 31/344 (9%)
Query: 272 LRFRREQQAAREKRNPAKTLIDADASHSGTESN-RPQKKKKRNETPEPTKGKDASQPSME 330
LR +REQ+ A K K+L + +H G ++ R + ++ N + + ++ +E
Sbjct: 1252 LRSKREQELATLK----KSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLE 1307
Query: 331 KFM--MKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNL 388
K ++ LA + S ++ K+ E +E L + + + L E
Sbjct: 1308 KAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCT 1367
Query: 389 VFKADQEKI----KRIGLKEACQAIMTKGLE--IAAISKMVDLETAGFDGINSAKQLEEK 442
+ + E I + LK + +E + ++++ ET G++S + E
Sbjct: 1368 KLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIES 1427
Query: 443 EREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEA-LSATQKVKEG------EL 495
E+E L+ + ++ D + + E+K A++ + + +KK AE ++++EG ++
Sbjct: 1428 EKEALQEQ--LEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDI 1485
Query: 496 VKSQAEITELNSANSELKNENSKLHSEISELKNSI---------LDQLEAGFSKAKEQIL 546
+ ++ EL + N L K+ SE+ + + L++ + F K +
Sbjct: 1486 EALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEK 1545
Query: 547 FLNPQVSINLAGSNPYARIVDGKLINPDTGDEEEEEEYEGDKNE 590
++ Q++ + AR + K+++ +E ++ E +N+
Sbjct: 1546 AISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENK 1589
Score = 33.9 bits (76), Expect = 1.3
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 27/136 (19%)
Query: 437 KQLEEKEREILKMKATMKLLDSSNKVSEKKAA-------DLALENERLKKHAEALSATQK 489
+QLEE+E K++ LD+ K E+ A L E + L++ A LS T
Sbjct: 1041 EQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLA 1100
Query: 490 VKEGEL-------VKSQAEITEL-------NSANSELKNENSKLHSEISELKNSI----- 530
+E + K +A ITEL E K+ +E+++LK +
Sbjct: 1101 EEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRV 1160
Query: 531 -LDQLEAGFSKAKEQI 545
+D+++A +K +E++
Sbjct: 1161 QVDEMQAQLAKREEEL 1176
Score = 31.6 bits (70), Expect = 6.3
Identities = 42/180 (23%), Positives = 83/180 (45%), Gaps = 32/180 (17%)
Query: 382 ALVETNLVFKADQEKIKRIG-LKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLE 440
ALVE + + Q +I+ +E+ +M + E+ + M +LET ++E
Sbjct: 969 ALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDM--MQELET----------RIE 1016
Query: 441 EKEREIL-----KMKATMKLLDSSNKVSEKKAADLALENER------LKKHAEALSAT-- 487
E+E +L K K + + D ++ E++AA L+ E+ +KK+ E L+ T
Sbjct: 1017 EEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDD 1076
Query: 488 ---QKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQ 544
+ +KE +L++ +A A E E +K +++ + + +LE K ++Q
Sbjct: 1077 QNQKLLKEKKLLEERANDLSQTLAEEE---EKAKHLAKLKAKHEATITELEERLHKDQQQ 1133
>YA8D_SCHPO (Q09778) Hypothetical protein C22F3.13 in chromosome I
Length = 899
Score = 44.7 bits (104), Expect = 7e-04
Identities = 52/267 (19%), Positives = 125/267 (46%), Gaps = 24/267 (8%)
Query: 266 LSDDDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKDAS 325
L + +I + R E QAA +R + + ++ ++ R +KK ++E E ++
Sbjct: 608 LLNSEIDKHRSESQAALNRRVKWE-----NDFNNKIKALREEKKAWKSEESELKSSIESL 662
Query: 326 QPSMEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEE-----------LTSEEVTSLW 374
+E ++N+ +A +++ LKE+E+ ++S TS
Sbjct: 663 ISQLES--IRNSQIDIAFSKNQLELKLQLYETKLKEYEQHLSCVNISKKQVSSSSDTSFG 720
Query: 375 DSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGIN 434
++K+D ++++ +N +D+++ + I ++ + ++ L + A +++ + + +
Sbjct: 721 NTKMD-SSMILSNSEAVSDEQERELIESEKHRMKLESENLHLQANIELLKKDLEAINVVY 779
Query: 435 SAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGE 494
AK + ++R + + + N V+ A L+ +E +K++ + L + EG+
Sbjct: 780 EAKIFDLEKR----LSSEANAPELHNPVNLNYDAQLSKISE-IKENYDELLTRYRELEGK 834
Query: 495 LVKSQAEITELNSANSELKNENSKLHS 521
++SQAE+ EL + L + S +HS
Sbjct: 835 FLESQAEVEELKNFQKPLVDTGSSIHS 861
>MYSP_SCHJA (Q05870) Paramyosin (Antigen Sj97)
Length = 866
Score = 44.7 bits (104), Expect = 7e-04
Identities = 40/182 (21%), Positives = 81/182 (43%), Gaps = 30/182 (16%)
Query: 367 SEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLE 426
SEE ++L + FNA + L K ++E +M+K E + + + +
Sbjct: 267 SEEASNLRNQVSKFNADIAA-LKSKFERE-------------LMSKTEEFEEMKRKLTMR 312
Query: 427 TAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSE------------KKAADLALEN 474
+ + ++L+ E LK K T+++ D +++ K A LA E
Sbjct: 313 ITELEDVAERERLKAVSLEKLKTKLTLEIKDLQSEIESLSLENGELIRRAKSAESLASEL 372
Query: 475 ER----LKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEISELKNSI 530
+R L L++ E E ++ ++ + +L N+ L+ EN +++ ++ ELK+S+
Sbjct: 373 QRRVDELTIEVNTLTSQNNQLESENMRLKSLVNDLTDKNNALERENRQMNDQVKELKSSL 432
Query: 531 LD 532
D
Sbjct: 433 RD 434
Score = 35.8 bits (81), Expect = 0.33
Identities = 61/274 (22%), Positives = 115/274 (41%), Gaps = 38/274 (13%)
Query: 285 RNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKD----ASQPSMEKFMMKNNPQH 340
R+ + L D +A S E+ R ++ E + D ASQ ++ + Q
Sbjct: 433 RDANRRLTDLEALRSQLEAERDNLASALHDAEEALRDMDQKYQASQAALNH-LKSEMEQR 491
Query: 341 LAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRI 400
L + + KS + EELT K + + L + AD E I+
Sbjct: 492 LRERDEELES---LRKSTTRTIEELTVTITEMEVKYKSELSRLKKRYESSIADLE-IQLD 547
Query: 401 GLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSN 460
+A +M + +A ++ DLET ++ ++L E L++ K + +N
Sbjct: 548 ATNKANANLMKENKNLA--QRVKDLETF----LDDERRLREAAENNLQI-TEHKRIQLAN 600
Query: 461 KVSEKKAADLALEN-ERLKKHAEA------------------LSATQKVKEGELVKSQAE 501
+V E ++A +EN ERL+KHAE LS ++ EG++ QA+
Sbjct: 601 EVEELRSA---MENLERLRKHAETELEETQSRVSELTIQVNTLSNDKRRLEGDIGVMQAD 657
Query: 502 ITELNSANSELKNENSKLHSEISELKNSILDQLE 535
+ + +A ++ ++L++E+ L + + + E
Sbjct: 658 MDDAINAKQAAEDRATRLNNEVLRLADELRQEQE 691
>DESP_HUMAN (P15924) Desmoplakin (DP) (250/210 kDa paraneoplastic
pemphigus antigen)
Length = 2871
Score = 44.7 bits (104), Expect = 7e-04
Identities = 45/198 (22%), Positives = 90/198 (44%), Gaps = 11/198 (5%)
Query: 354 TWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRI--GLKEACQAIMT 411
T +++ + E++ ++ T S+ VE V + E+ R L +A + I
Sbjct: 1419 TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQD 1478
Query: 412 KGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLA 471
K EI + +++D ET N K LE++ + +++ ++ +SS + K
Sbjct: 1479 KNKEIERLKQLIDKET------NDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQE 1532
Query: 472 LENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLH---SEISELKN 528
E RL+ E +S + VK+ ++ + Q + EL +++ E ++L SE S +
Sbjct: 1533 QELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRK 1592
Query: 529 SILDQLEAGFSKAKEQIL 546
+ ++LE KEQ +
Sbjct: 1593 KLEEELEGMRRSLKEQAI 1610
Score = 38.1 bits (87), Expect = 0.067
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 8/156 (5%)
Query: 386 TNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKERE 445
T L ++ + EK +R +++ + ++ + E G+ + S K ++EKE E
Sbjct: 1112 TRLTYEIEDEKRRRKSVEDRFDQ-QKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYE 1170
Query: 446 ILKMKATMKLLDSSNKVSEKKAADLA------LENERLKKHAEALSATQKVKEGELVKSQ 499
I +++ ++ + + E + A + + N R K E +KE + K
Sbjct: 1171 IERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKED 1230
Query: 500 AEITELNSANSELKNENSKLHSEISELKNSILDQLE 535
+ L + L EN L EI L +SIL E
Sbjct: 1231 -DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATE 1265
>MYSS_CHICK (P13538) Myosin heavy chain, skeletal muscle, adult
Length = 1938
Score = 43.9 bits (102), Expect = 0.001
Identities = 56/222 (25%), Positives = 98/222 (43%), Gaps = 20/222 (9%)
Query: 382 ALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGF----DGINSAK 437
A +E N +A+ +K++R + +A + AA+ K TA D + K
Sbjct: 1161 AQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVK 1216
Query: 438 QLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEGELVK 497
Q EKE+ LKM+ L + VS+ KA E++ + E + K KE +
Sbjct: 1217 QKLEKEKSELKMEID-DLASNMESVSKAKA-----NLEKMCRTLEDQLSEIKTKEEQ--- 1267
Query: 498 SQAEITELNSANSELKNENSKLHSEISELKNSILDQLEAGFSKAKEQILFLNPQVSINLA 557
+Q I +LN+ + L+ E + +S +E K++++ QL G +QI L + +
Sbjct: 1268 NQRMINDLNTQRARLQTETGE-YSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIK 1326
Query: 558 GSNPYARIVDGKLINPDTGDE--EEEEEYEGDKNEEDGNANN 597
N A + + + E EEE+E +G+ AN+
Sbjct: 1327 AKNALAHALQSARHDCELLREQYEEEQEAKGELQRALSKANS 1368
Score = 36.6 bits (83), Expect = 0.19
Identities = 33/122 (27%), Positives = 62/122 (50%), Gaps = 16/122 (13%)
Query: 434 NSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAADLALENERLKKHAEALSATQKVKEG 493
N ++ E+ + E+ K +A K L+ V ++ DL L+ ++ A++L+ ++ +
Sbjct: 853 NMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQ---VQAEADSLADAEE-RCD 908
Query: 494 ELVKSQA-------EITEL----NSANSELKNENSKLHSEISELKNSILDQLEAGFSKAK 542
+L+K++ E+TE N+EL + KL E SELK I D LE +K +
Sbjct: 909 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI-DDLELTLAKVE 967
Query: 543 EQ 544
++
Sbjct: 968 KE 969
Score = 35.8 bits (81), Expect = 0.33
Identities = 45/212 (21%), Positives = 91/212 (42%), Gaps = 20/212 (9%)
Query: 407 QAIMTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKK 466
+ + K EI+ I ++ E A G+ K+++E + I +++ ++ +S +EK
Sbjct: 1080 EKLKKKDFEISQIQSKIEDEQAL--GMQLQKKIKELQARIEELEEEIEAERTSRAKAEKH 1137
Query: 467 AADLALE----NERLKKHAEALSA---TQKVKEGELVKSQAEITELNSANSELKNENSKL 519
ADL+ E +ERL++ A +A K +E E K + ++ E + K
Sbjct: 1138 RADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 520 HSEISELKNSILDQLEAGFSKAKEQILFLNPQV--------SINLAGSN--PYARIVDGK 569
H++ + +D L+ K +++ L ++ S++ A +N R ++ +
Sbjct: 1198 HADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQ 1257
Query: 570 LINPDTGDEEEEEEYEGDKNEEDGNANNNEGE 601
L T EE+ + D N + GE
Sbjct: 1258 LSEIKT-KEEQNQRMINDLNTQRARLQTETGE 1288
Score = 33.1 bits (74), Expect = 2.2
Identities = 34/127 (26%), Positives = 55/127 (42%), Gaps = 25/127 (19%)
Query: 435 SAKQLEEKEREILKMKAT-------MKLLDSSNKVSEKKAADL----------ALENERL 477
S K+ E+ KMK ++ L NK +++ ADL E E++
Sbjct: 1472 SQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGKAVHELEKV 1531
Query: 478 KKHAE----ALSATQKVKEGELVKSQAEI----TELNSANSELKNENSKLHSEISELKNS 529
KKH E L A+ + E L + +I ELN SE+ + ++ EI +LK +
Sbjct: 1532 KKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEIDRKIAEKDEEIDQLKRN 1591
Query: 530 ILDQLEA 536
L +E+
Sbjct: 1592 HLRIVES 1598
Score = 31.6 bits (70), Expect = 6.3
Identities = 21/80 (26%), Positives = 38/80 (47%)
Query: 464 EKKAADLALENERLKKHAEALSATQKVKEGELVKSQAEITELNSANSELKNENSKLHSEI 523
E++ DL E+ KK L ++ EG+L + I +L + +L + K EI
Sbjct: 1030 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEI 1089
Query: 524 SELKNSILDQLEAGFSKAKE 543
S++++ I D+ G K+
Sbjct: 1090 SQIQSKIEDEQALGMQLQKK 1109
>IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B
(eIF-5B) (Translation initiation factor IF-2)
Length = 1220
Score = 43.9 bits (102), Expect = 0.001
Identities = 83/394 (21%), Positives = 149/394 (37%), Gaps = 76/394 (19%)
Query: 269 DDILRFRREQQAAREKRNPAKTLIDADASHSGTESNRPQKKKKRNETPEPTKGKDASQPS 328
D+ L+ R+ Q+ +K P + + + + +KK + K +D +
Sbjct: 191 DEFLQSRKGQKK-NQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAK 249
Query: 329 MEKFMMKNNPQHLAHQSGSSSAPPPTWKSVLKEFEELTSEEVTSLWDSKIDFN------- 381
+ K K + + K ++FEE T + ++ I +
Sbjct: 250 LRKLKEKEELE-------TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP 302
Query: 382 -ALVETNLVFKADQEKIKRIGLKEACQAIMTKGLEIAAISKMVDLETAGFDGINSAKQLE 440
A + N K ++K K+ G KE + KG A + M + AK E
Sbjct: 303 TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA---------LAKLKE 353
Query: 441 EKEREILKMKATMKLLDS-----------SNKVSEKKAADLALENERLKKHAEALSATQK 489
E+ER+ + + +K L+ + E+K ERLKK + L+ +Q+
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQR 413
Query: 490 VK----EGELVKSQAEITELNSANSELKNE---------------NSKLHSEISELKNSI 530
E L QA+ E+ S +S K SK SE EL ++
Sbjct: 414 EARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAV 473
Query: 531 LDQLEAGFSKAKEQILFLNPQVSINLA----------GSNPYARIVDGKLI------NPD 574
+ +E G + +E + P+ + S+ V+G + NP+
Sbjct: 474 -EVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPE 532
Query: 575 TGDEEEEEEYEGDKNEED----GNANNNEGEGEN 604
+EEEEEE E +++EE+ G + +EG+ E+
Sbjct: 533 EEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
>SMC3_RAT (P97690) Structural maintenance of chromosome 3
(Chondroitin sulfate proteoglycan 6) (Chromosome
segregation protein SmcD) (Bamacan) (Basement
membrane-associated chondroitin proteoglycan)
Length = 1191
Score = 43.5 bits (101), Expect = 0.002
Identities = 65/270 (24%), Positives = 105/270 (38%), Gaps = 25/270 (9%)
Query: 252 YENKLGEYVAKMTRLS------DDDILRFRREQQAAREKRNPAKTLI-DADASHSGTESN 304
Y +L E AK+ LS + + R QQ AR+K + + + S +
Sbjct: 228 YNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEE 287
Query: 305 RPQKKKKRNE-----TPEPTKGKD-----ASQPSMEKFMMKNNP---QHLAHQSGSSSAP 351
+ Q +R E T K KD A K ++K + + + +
Sbjct: 288 KEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAET 347
Query: 352 PPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIG--LKEACQAI 409
P + SV KE EE + + D A F + +E+ K I LK QAI
Sbjct: 348 EPKFNSV-KEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAI 406
Query: 410 MTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAAD 469
K +IAAI K DLE + + +Q + ++++ ++KA ++ LD + K +
Sbjct: 407 NDKKRQIAAIHK--DLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDE 464
Query: 470 LALENERLKKHAEALSATQKVKEGELVKSQ 499
L E L + A K +L K Q
Sbjct: 465 LQSERNYLWREENAEQQALAAKREDLEKKQ 494
>SMC3_MOUSE (Q9CW03) Structural maintenance of chromosome 3
(Chondroitin sulfate proteoglycan 6) (Chromosome
segregation protein SmcD) (Bamacan) (Basement
membrane-associated chondroitin proteoglycan) (Mad
member-interacting protein 1)
Length = 1217
Score = 43.5 bits (101), Expect = 0.002
Identities = 65/270 (24%), Positives = 105/270 (38%), Gaps = 25/270 (9%)
Query: 252 YENKLGEYVAKMTRLS------DDDILRFRREQQAAREKRNPAKTLI-DADASHSGTESN 304
Y +L E AK+ LS + + R QQ AR+K + + + S +
Sbjct: 228 YNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEE 287
Query: 305 RPQKKKKRNE-----TPEPTKGKD-----ASQPSMEKFMMKNNP---QHLAHQSGSSSAP 351
+ Q +R E T K KD A K ++K + + + +
Sbjct: 288 KEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAET 347
Query: 352 PPTWKSVLKEFEELTSEEVTSLWDSKIDFNALVETNLVFKADQEKIKRIG--LKEACQAI 409
P + SV KE EE + + D A F + +E+ K I LK QAI
Sbjct: 348 EPKFNSV-KEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAI 406
Query: 410 MTKGLEIAAISKMVDLETAGFDGINSAKQLEEKEREILKMKATMKLLDSSNKVSEKKAAD 469
K +IAAI K DLE + + +Q + ++++ ++KA ++ LD + K +
Sbjct: 407 NDKKRQIAAIHK--DLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDE 464
Query: 470 LALENERLKKHAEALSATQKVKEGELVKSQ 499
L E L + A K +L K Q
Sbjct: 465 LQSERNYLWREENAEQQALAAKREDLEKKQ 494
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.130 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,482,361
Number of Sequences: 164201
Number of extensions: 3218195
Number of successful extensions: 17229
Number of sequences better than 10.0: 664
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 563
Number of HSP's that attempted gapping in prelim test: 15007
Number of HSP's gapped (non-prelim): 2032
length of query: 605
length of database: 59,974,054
effective HSP length: 116
effective length of query: 489
effective length of database: 40,926,738
effective search space: 20013174882
effective search space used: 20013174882
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Lotus: description of TM0214.3