BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0211.11
         (298 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ZAP3_MOUSE (Q9R0I7) Nuclear protein ZAP3                               36  0.10
APT_CLOTE (Q892A7) Adenine phosphoribosyltransferase (EC 2.4.2.7...    35  0.29
RL7A_AERPE (Q9YAX7) 50S ribosomal protein L7Ae                         34  0.38
APT_PASMU (P57841) Adenine phosphoribosyltransferase (EC 2.4.2.7...    33  0.86
TRXB_MYCPU (Q98PK9) Thioredoxin reductase (EC 1.8.1.9) (TRXR)          33  1.1
YDC9_SCHPO (Q10172) Hypothetical protein C25G10.09c in chromosome I    32  1.9
RRPL_RDVA (Q02119) RNA-directed RNA polymerase (EC 2.7.7.48) (Re...    32  1.9
WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7...    32  2.5
R3HD_HUMAN (Q15032) R3H domain protein 1                               32  2.5
MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.1.-)         32  2.5
ESR1_BOVIN (P49884) Estrogen receptor (ER) (Estradiol receptor) ...    31  3.3
RRPL_RDVF (Q98631) RNA-directed RNA polymerase (EC 2.7.7.48) (Re...    31  4.2
PGCN_RAT (P55067) Neurocan core protein precursor (Chondroitin s...    31  4.2
NQRD_NEIMB (Q9K0M6) Na(+)-translocating NADH-quinone reductase s...    31  4.2
VBL1_CLVN (P14971) BL1 protein (33.7 kDa protein)                      30  5.5
S6AG_HUMAN (Q9GZN6) Orphan sodium- and chloride-dependent neurot...    30  5.5
GCSR_HUMAN (Q99062) Granulocyte colony stimulating factor recept...    30  5.5
ATF7_HUMAN (P17544) Cyclic-AMP-dependent transcription factor AT...    30  5.5
YNI7_YEAST (P48231) Hypothetical 132.5 kDa protein in TOP2-MKT1 ...    30  7.2
VBL1_CLVK (P14981) BL1 protein (33.7 kDa protein)                      30  7.2

>ZAP3_MOUSE (Q9R0I7) Nuclear protein ZAP3
          Length = 1386

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 19/69 (27%), Positives = 31/69 (44%)

Query: 5   FPPHMTLPPLSSIKPSPTRLLLSPPSPLPKSNSLFCSRPIISSLRKNQTLSLKPSLASSG 64
           +PP    P L   +PSP++  L PP  +P  N     +  + S  KN+T   K +     
Sbjct: 176 YPPSSAQPYLPPAQPSPSKPQLPPPPSIPSGNKTAIQQEPLESGAKNKTAEQKQAAPEPD 235

Query: 65  TSWLSHAQQ 73
            S ++  +Q
Sbjct: 236 PSTMTPQEQ 244


>APT_CLOTE (Q892A7) Adenine phosphoribosyltransferase (EC 2.4.2.7)
           (APRT)
          Length = 172

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 7/98 (7%)

Query: 127 DLKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVLERWYPSVEEGNDKGIVVLVTS 186
           DLK  +  ++   K  I+F  V  +  + +AF+Y    L      VEE  DK + V+V  
Sbjct: 2   DLKDKIRVIQGFPKEGISFKDVTTILQEKEAFKYTIDTL------VEELKDKNVDVVVGP 55

Query: 187 QKEGAVTGGPAFVQAVGENILDATVAENLPVLATDEKY 224
           +  G + G P    A+G   +       LP      KY
Sbjct: 56  EARGFLFGAP-LAYALGAGFVPVRKKGKLPSTTISSKY 92


>RL7A_AERPE (Q9YAX7) 50S ribosomal protein L7Ae
          Length = 127

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 19/78 (24%), Positives = 39/78 (49%)

Query: 158 FEYADQVLERWYPSVEEGNDKGIVVLVTSQKEGAVTGGPAFVQAVGENILDATVAENLPV 217
           FE  + + E+ Y +V+   + G +   T++   AV  G A +  + E++    +  +LP+
Sbjct: 9   FEVPEDLAEKAYEAVKRARETGRIKKGTNETTKAVERGLAKLVVIAEDVDPPEIVMHLPL 68

Query: 218 LATDEKYNEAVLSTAKRL 235
           L  ++K     + + KRL
Sbjct: 69  LCDEKKIPYVYVPSKKRL 86


>APT_PASMU (P57841) Adenine phosphoribosyltransferase (EC 2.4.2.7)
           (APRT)
          Length = 180

 Score = 33.1 bits (74), Expect = 0.86
 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 16/137 (11%)

Query: 103 LNEVPAKDSYVVD-------DAGVLSRVTRSDLKGLLSDLESRKKFHINFITVRK----- 150
           L EVPA    VVD       + G+ ++V  ++ +G +         ++ F+ VRK     
Sbjct: 31  LLEVPAAFQTVVDLFVTRYKEKGI-TKVLGTESRGFIFGAPVALALNVPFVLVRKPGKLP 89

Query: 151 --LTSKADAFEYADQVLERWYPSVEEGNDKGIVVLVTSQKEGAVTGGPAFVQAVGENILD 208
               S+    EY    LE    ++    DK +++       G V      VQ +G ++ D
Sbjct: 90  RETISQTYQLEYGQDTLEIHTDAIH-AQDKVLIIDDLLATGGTVEATVKLVQRLGGDVQD 148

Query: 209 ATVAENLPVLATDEKYN 225
           A    NLP L  + + N
Sbjct: 149 AAFVINLPDLGGEARLN 165


>TRXB_MYCPU (Q98PK9) Thioredoxin reductase (EC 1.8.1.9) (TRXR)
          Length = 307

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 23/70 (32%), Positives = 38/70 (53%), Gaps = 8/70 (11%)

Query: 93  GNALASEFDVLNEVPAKDSYVVDDAGVLSRVTRSDLKGLLSDLESRKKFHINF-ITVRKL 151
           GN+   E   L+ + +K   +V D+  ++       K L++DL+SRK   + F  +V++L
Sbjct: 157 GNSAVEEGTFLSSIASKVYVIVRDSDFIAE------KALVNDLKSRKNIEVLFNASVKEL 210

Query: 152 TSKADAFEYA 161
             K DA EYA
Sbjct: 211 HGK-DALEYA 219


>YDC9_SCHPO (Q10172) Hypothetical protein C25G10.09c in chromosome I
          Length = 1794

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 14/32 (43%), Positives = 19/32 (58%)

Query: 6    PPHMTLPPLSSIKPSPTRLLLSPPSPLPKSNS 37
            PP M++PP  S  P P     +PP PLP S++
Sbjct: 1709 PPPMSVPPPPSAPPMPAGPPSAPPPPLPASSA 1740


>RRPL_RDVA (Q02119) RNA-directed RNA polymerase (EC 2.7.7.48)
           (Replicase)
          Length = 1444

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 43/157 (27%), Positives = 60/157 (37%), Gaps = 34/157 (21%)

Query: 90  FLSGNALASEFDVLNEVPAKDSYVVDDAGVLSRVTRSDLKGLL------SDLESRKKFHI 143
           FLSG       D+LN   A     ++D G   R+T+S L G        SDLE++     
Sbjct: 490 FLSGADPEKNIDILNAWMAP---TMEDCGY--RLTKSILFGKFRKAKYPSDLEAKSNIDY 544

Query: 144 NFITVRKLTSKADAFEYADQVLERWYPSVEEGNDKGIVVLVTSQKEGAVTGGPAFVQAVG 203
            ++T R                     S   GN +  +     + +   T   AFV A+G
Sbjct: 545 -YVTAR---------------------SAGIGNLRISIETDKRKYKVRTTSKSAFVNAMG 582

Query: 204 ENILDATVAENLPVLATDEKYNEAVLSTAKRLVAAID 240
             ILD     N P++ TD    +    T   L AAID
Sbjct: 583 SGILDVNPVSNEPMMLTDYLLTQTP-ETRANLEAAID 618


>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC
           2.7.1.37) (Protein kinase with no lysine 2) (Protein
           kinase, lysine-deficient 2) (P/OKcl.13)
          Length = 2297

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 14/42 (33%), Positives = 21/42 (49%), Gaps = 4/42 (9%)

Query: 4   IFPPHMTLPPLSSIKPSPTRLLLSPPSPLPKSNSLFCSRPII 45
           + PP  TLPP   + P PTR    PP P+     +   +P++
Sbjct: 955 VLPPQPTLPPQPVLPPQPTR----PPQPVLPPQPMLPPQPVL 992


>R3HD_HUMAN (Q15032) R3H domain protein 1
          Length = 971

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 17/60 (28%), Positives = 29/60 (48%)

Query: 4   IFPPHMTLPPLSSIKPSPTRLLLSPPSPLPKSNSLFCSRPIISSLRKNQTLSLKPSLASS 63
           ++ P MT  P+ S  P P +  L  P   P +N +F  +  + S   + +L+ +PS   S
Sbjct: 375 VYNPPMTQQPVRSQVPGPPQPPLPAPPQQPAANHIFSQQDNLGSQFSHMSLARQPSADGS 434


>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.1.-)
          Length = 1116

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 30/135 (22%), Positives = 61/135 (44%), Gaps = 1/135 (0%)

Query: 46  SSLRKNQTLSLKPSLASSGTSWLSHAQQGLAALAITLALNFSPIFLSGNALASEFDVLNE 105
           SSLR+  TL+ +PS+  + +S         A+     + +      S N+L    + L+E
Sbjct: 551 SSLRRKNTLTRRPSIRHARSSPYIDTGHNEASKFSHTSFDPKASSKSSNSLKESVEALSE 610

Query: 106 VPAKDSYVVDDAGVLSRVTRSDLKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVL 165
           +P +D+  +D++  LS      ++   S  +  K+ H N  +   + ++A     A+++ 
Sbjct: 611 IPFEDAPALDESD-LSGDPFWAIQPKQSSSQVPKENHHNIQSKLSINTEAATDLKANELS 669

Query: 166 ERWYPSVEEGNDKGI 180
               P    G+D+ I
Sbjct: 670 SPKTPEYCRGDDRSI 684


>ESR1_BOVIN (P49884) Estrogen receptor (ER) (Estradiol receptor)
           (ER-alpha)
          Length = 596

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 13/21 (61%), Positives = 15/21 (70%)

Query: 12  PPLSSIKPSPTRLLLSPPSPL 32
           PPL+S+ PSP  LL  PP PL
Sbjct: 98  PPLNSVSPSPLVLLHPPPQPL 118


>RRPL_RDVF (Q98631) RNA-directed RNA polymerase (EC 2.7.7.48)
           (Replicase)
          Length = 1444

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 1/48 (2%)

Query: 193 TGGPAFVQAVGENILDATVAENLPVLATDEKYNEAVLSTAKRLVAAID 240
           T   AFV A+G  ILD     N P++ TD    +    T   L AAID
Sbjct: 572 TSKSAFVNAMGSGILDVNPVSNEPMMLTDYLLTQTP-ETRANLEAAID 618


>PGCN_RAT (P55067) Neurocan core protein precursor (Chondroitin
           sulfate proteoglycan 3) (245 kDa early postnatal core
           glycoprotein) [Contains: 150 kDa adult core
           glycoprotein]
          Length = 1257

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 45/179 (25%), Positives = 67/179 (37%), Gaps = 37/179 (20%)

Query: 7   PHMTLPPLSSIKPSPTRLLLSPPSPLPKS-NSLFCSRPIISSLRKN----QTLSLKPSLA 61
           P + L P S++ P+ + + LSP SPLP S       RP+           QT    P  A
Sbjct: 642 PKLWLLPHSTLVPNVSPIPLSPASPLPSSVPEEQAVRPVSFGAEDPETPFQTTMAAPGEA 701

Query: 62  SSGTSWLSHAQ-QGLAALAITLALNFSPIFLSGNALASEFDVLNEVPAKDSYVVDDAGVL 120
           S G+      + +G++++  T      PI     +L S    +N VP+    +  ++GVL
Sbjct: 702 SHGSPEADSIEIEGISSMQATK----HPISGPWASLDSSNVTVNPVPSDAGILGTESGVL 757

Query: 121 SRVTRSDLKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVLERWYPSVEEGNDKG 179
                 DL G                     +  +D     D VL  W P    G D G
Sbjct: 758 ------DLPG---------------------SPTSDGQATVDMVLATWLPLPGHGLDTG 789


>NQRD_NEIMB (Q9K0M6) Na(+)-translocating NADH-quinone reductase
           subunit D (EC 1.6.5.-) (Na(+)-translocating NQR subunit
           D) (Na(+)-NQR subunit D) (NQR complex subunit D) (NQR-1
           subunit D)
          Length = 208

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 33/142 (23%), Positives = 56/142 (39%), Gaps = 9/142 (6%)

Query: 76  AALAITLALNFSPIFLSGNALASEFD------VLNEVPAKDSYVVDDAGVLSRVTRSD-- 127
           +ALA+T  L  + +     AL + F       V N +P     +V  A + S VT  D  
Sbjct: 30  SALAVTTKLQTAIVMGISVALVTGFSSFFISLVRNYIPNSIRIIVQMAIIASLVTLVDQL 89

Query: 128 LKGLLSDLESRKKFHINFITVRKLT-SKADAFEYADQVLERWYPSVEEGNDKGIVVLVTS 186
           L+    +L  +    +  I    +   +A+AF   +  LE     +  G   GI++LV +
Sbjct: 90  LQAFAYELSKQLSVFVGLIITNCIVMGRAEAFAMKEPPLESLIDGIGNGAGYGIMLLVVA 149

Query: 187 QKEGAVTGGPAFVQAVGENILD 208
                +  G      V + + D
Sbjct: 150 TVRELIGSGKLLGYTVFQTVQD 171


>VBL1_CLVN (P14971) BL1 protein (33.7 kDa protein)
          Length = 298

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 11/131 (8%)

Query: 68  LSHAQQGLAALAITLALNFSPIFLSGNALASEFDVLNEVPAKDSYVVDDAGVLSRVTRSD 127
           LS  QQ  A     +  N    + S    AS F + + VP +  Y V+D+ V + VT + 
Sbjct: 79  LSDEQQDQAQFTFPIGCNVDLHYFS----ASYFSIDDNVPWQLLYKVEDSNVKNGVTFAQ 134

Query: 128 LKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVLERWYPSVEEGNDKGIVVLVTSQ 187
           +K  L  L + K  H   I  ++ T K  + +Y    ++ W      G  K I  L+ ++
Sbjct: 135 IKAKLK-LSAAK--HSTDIRFKQPTIKILSKDYGPDCVDFW----SVGKPKPIRRLIQNE 187

Query: 188 KEGAVTGGPAF 198
                  GP +
Sbjct: 188 PGTDYDTGPKY 198


>S6AG_HUMAN (Q9GZN6) Orphan sodium- and chloride-dependent
          neurotransmitter transporter NTT5 (Solute carrier
          family 6 member 16)
          Length = 736

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 21/60 (35%), Positives = 27/60 (45%)

Query: 29 PSPLPKSNSLFCSRPIISSLRKNQTLSLKPSLASSGTSWLSHAQQGLAALAITLALNFSP 88
          PS    +N+ +    I  S+  +QT   K SL  S TSW S AQ   A +A   A    P
Sbjct: 7  PSTSLLANTSWTGTVISDSVPGSQTWEDKGSLTRSATSWTSEAQVSAARVAEAQARTSQP 66


>GCSR_HUMAN (Q99062) Granulocyte colony stimulating factor receptor
           precursor (G-CSF-R) (CD114 antigen)
          Length = 836

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 4/86 (4%)

Query: 1   MGTIFPPHMTLPPLSSIKPSPTRLLLSPPSP---LPKSNSL-FCSRPIISSLRKNQTLSL 56
           +GT   P + L P+  +K  P  L    PSP    P++  L  C  P    L  NQ   L
Sbjct: 209 LGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCEL 268

Query: 57  KPSLASSGTSWLSHAQQGLAALAITL 82
           +        SW       L AL   L
Sbjct: 269 RHKPQRGEASWALVGPLPLEALQYEL 294


>ATF7_HUMAN (P17544) Cyclic-AMP-dependent transcription factor ATF-7
           (Activating transcription factor 7) (Transcription
           factor ATF-A)
          Length = 494

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 16/53 (30%), Positives = 24/53 (45%)

Query: 6   PPHMTLPPLSSIKPSPTRLLLSPPSPLPKSNSLFCSRPIISSLRKNQTLSLKP 58
           P H+   PL    PSPT ++   P    +  S   S P++  L   QT+ + P
Sbjct: 168 PLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLP 220


>YNI7_YEAST (P48231) Hypothetical 132.5 kDa protein in TOP2-MKT1
           intergenic region
          Length = 1178

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 17/64 (26%), Positives = 34/64 (52%), Gaps = 6/64 (9%)

Query: 118 GVLSRVTRSDLKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVLERWYPSVEEGND 177
           G+L R +    +  L DL  +++      TV K+TS  ++ E+ +  L++++P +E    
Sbjct: 134 GMLYRTSSKKYRESLRDLAQKEQ------TVEKITSDYESVEWLNTFLDKYWPIIEPSVS 187

Query: 178 KGIV 181
           + IV
Sbjct: 188 QQIV 191


>VBL1_CLVK (P14981) BL1 protein (33.7 kDa protein)
          Length = 298

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 11/131 (8%)

Query: 68  LSHAQQGLAALAITLALNFSPIFLSGNALASEFDVLNEVPAKDSYVVDDAGVLSRVTRSD 127
           LS  QQ  A     +  N    + S    AS F + + VP +  Y V+D+ V + +T + 
Sbjct: 79  LSDEQQDQAQFTFPIGCNVDLHYFS----ASYFSIDDNVPWQLLYKVEDSNVKNGITFAQ 134

Query: 128 LKGLLSDLESRKKFHINFITVRKLTSKADAFEYADQVLERWYPSVEEGNDKGIVVLVTSQ 187
           +K  L  L + K  H   I  ++ T K  + +Y    ++ W      G  K I  L+ ++
Sbjct: 135 IKAKLK-LSAAK--HSTDIKFKQPTIKILSKDYGPDCVDFW----SVGKPKPIRRLIQNE 187

Query: 188 KEGAVTGGPAF 198
                  GP +
Sbjct: 188 PGTDYDTGPKY 198


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.315    0.133    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,943,695
Number of Sequences: 164201
Number of extensions: 1428971
Number of successful extensions: 3761
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3734
Number of HSP's gapped (non-prelim): 48
length of query: 298
length of database: 59,974,054
effective HSP length: 109
effective length of query: 189
effective length of database: 42,076,145
effective search space: 7952391405
effective search space used: 7952391405
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)