BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0180a.12
(1023 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ODO1_YEAST (P20967) 2-oxoglutarate dehydrogenase E1 component, m... 938 0.0
ODO1_HUMAN (Q02218) 2-oxoglutarate dehydrogenase E1 component, m... 881 0.0
ODO1_MOUSE (Q60597) 2-oxoglutarate dehydrogenase E1 component, m... 879 0.0
ODO1_COXBU (P51056) 2-oxoglutarate dehydrogenase E1 component (E... 720 0.0
ODO1_ALCEU (Q59106) 2-oxoglutarate dehydrogenase E1 component (E... 706 0.0
ODO1_RICCN (Q92J42) 2-oxoglutarate dehydrogenase E1 component (E... 705 0.0
ODO1_ECOLI (P07015) 2-oxoglutarate dehydrogenase E1 component (E... 702 0.0
ODO1_RICPR (Q9ZDY3) 2-oxoglutarate dehydrogenase E1 component (E... 701 0.0
ODO1_AZOVI (P20707) 2-oxoglutarate dehydrogenase E1 component (E... 694 0.0
ODO1_HAEIN (P45303) 2-oxoglutarate dehydrogenase E1 component (E... 686 0.0
ODO1_BUCAP (Q8K9N3) 2-oxoglutarate dehydrogenase E1 component (E... 647 0.0
ODO1_BUCAI (P57388) 2-oxoglutarate dehydrogenase E1 component (E... 631 e-180
ODO1_BUCBP (Q89AJ7) Oxoglutarate dehydrogenase (EC 1.2.4.2) 621 e-177
ODO1_BACSU (P23129) 2-oxoglutarate dehydrogenase E1 component (E... 553 e-157
ODPA_RHIME (Q9R9N5) Pyruvate dehydrogenase E1 component, alpha s... 67 2e-10
ODPT_ASCSU (P26268) Pyruvate dehydrogenase E1 component alpha su... 56 4e-07
ODPA_KLULA (O13366) Pyruvate dehydrogenase E1 component alpha su... 54 3e-06
ODPA_CAEEL (P52899) Probable pyruvate dehydrogenase E1 component... 53 4e-06
ODPA_MYCPN (P75390) Pyruvate dehydrogenase E1 component, alpha s... 52 8e-06
ODPA_ASCSU (P26267) Pyruvate dehydrogenase E1 component alpha su... 52 1e-05
>ODO1_YEAST (P20967) 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor (EC 1.2.4.2) (Alpha-ketoglutarate
dehydrogenase)
Length = 1014
Score = 938 bits (2424), Expect = 0.0
Identities = 479/1029 (46%), Positives = 677/1029 (65%), Gaps = 61/1029 (5%)
Query: 28 YVTRTTNLPSTSRKLHTTIFKSEAHAAPVPRPVPLSRLTDNFLDGTSSAYLEELQRAWEA 87
+V+ T S+ L T++ K+ + V R + + TDNFL +++ Y++E+ +AW+
Sbjct: 4 FVSSQTCRYSSRGLLKTSLLKNASTVKIVGRGLATTG-TDNFLSTSNATYIDEMYQAWQK 62
Query: 88 DPSSVDESWDNFFRNF----------------------------VGQASTSPGISGQTIQ 119
DPSSV SWD +F+N +G A T G + +
Sbjct: 63 DPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLGTAMT--GSVDENVS 120
Query: 120 ESMRLLLLVRAYQVNGHMKAKLDPLGL-----KERNIPDELDPGLYGFTEADLDREFFLG 174
+++ LL RAYQV GH+KA +DPLG+ K +P EL YGF++ DLD+E LG
Sbjct: 121 IHLKVQLLCRAYQVRGHLKAHIDPLGISFGSNKNNPVPPELTLDYYGFSKHDLDKEINLG 180
Query: 175 VWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPTQF 234
+ F + + +L+ I+ LE+ YC S G +Y HIP + KC+WLR++IE P P Q+
Sbjct: 181 PGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQY 240
Query: 235 SRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVENIV 294
+ +++ I DRL W+T FE+FL+TK+ + KRFGLEG E+++PG+K + DR+ +LGVE+IV
Sbjct: 241 TVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIV 300
Query: 295 MGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKYHLGTSYDRPTRGG 354
+GMAHRGRLNVL NVVRKP IF EF G +D++ G+GDVKYHLG +Y RPT G
Sbjct: 301 LGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDI---EGSGDVKYHLGMNYQRPTTSG 357
Query: 355 RRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDA-ERMKNMGVLIHGDGSFAGQGVVYE 413
+ ++LSL+ANPSHLE+ +P+V+G+TRA + ND E+ K +GVL+HGD +FAGQGVVYE
Sbjct: 358 KYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYE 417
Query: 414 TLHLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVES 473
T+ LP Y+TGGTIH++ NNQ+ FTTDP RS+ Y +D+AKA++APIFHVN +DVE+
Sbjct: 418 TMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEA 477
Query: 474 VVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQK 533
V + LAAEWR FH+D ++D+V +R+ GHNE D+PSFTQP MYK I S +++Y +
Sbjct: 478 VTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTE 537
Query: 534 KLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGFKSPEQLSR--- 590
KL+ G +++DID+ K V ++ D F +KDY+P +R+WL+A W GFKSP++L+
Sbjct: 538 KLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKDYVPSQREWLTAAWEGFKSPKELATEIL 597
Query: 591 -IRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEALAFA 649
T V LK +GK +++ PE H+ +K++ + R + +ETGE IDW EALAF
Sbjct: 598 PHEPTNVPESTLKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFG 657
Query: 650 TLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEMFTVSNSSLS 709
TL+++G +VR+SG+DVERGTFS RHAV+HDQ + Y PL +N + FT++NSSLS
Sbjct: 658 TLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAIYTPLS--TLNNEKADFTIANSSLS 715
Query: 710 EFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLVVLLPH 769
E+GV+GFE GYS+ +P+ LV+WEAQFGDFAN AQVI D F++ GE KW +++GLV+ LPH
Sbjct: 716 EYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPH 775
Query: 770 GYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTTPANFFHVLR 829
GYDGQGPEHSSGRLER+LQ+A++ P P + L++Q Q+CN Q+V TTPAN FH+LR
Sbjct: 776 GYDGQGPEHSSGRLERFLQLANEDPRYFPS-EEKLQRQHQDCNFQVVYPTTPANLFHILR 834
Query: 830 RQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSN 889
RQ HR+FRKPL + K LLR + RS+LSEF + F+ +I+D +
Sbjct: 835 RQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTE-----------GGFQWIIEDIEHGKS 883
Query: 890 V--EEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRELKRYPN-A 946
+ +E +RL+L SG+VY L ++R K A ++EQL PFP+ ++ L YPN
Sbjct: 884 IGTKEETKRLVLLSGQVYTALHKRRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLE 943
Query: 947 EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKVHQREQ 1006
E+VWCQEEP+NMG ++Y PRL T++K + V+Y GR PS A A G +H E+
Sbjct: 944 EIVWCQEEPLNMGSWAYTEPRLHTTLKETDKYKDFKVRYCGRNPSGAVAAGSKSLHLAEE 1003
Query: 1007 AELVHKAMQ 1015
+ Q
Sbjct: 1004 DAFLKDVFQ 1012
>ODO1_HUMAN (Q02218) 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor (EC 1.2.4.2) (Alpha-ketoglutarate
dehydrogenase)
Length = 1002
Score = 881 bits (2276), Expect = 0.0
Identities = 475/1021 (46%), Positives = 637/1021 (61%), Gaps = 88/1021 (8%)
Query: 30 TRTTNLPSTSRKLHTTIFKSEAHAAPVPRPVPLSRLTDNFLDGTSSAYLEELQRAWEADP 89
T + N P+ +R T + ++APV + FL GTSS Y+EE+ AW +P
Sbjct: 22 TFSQNRPAAAR----TFQQIRCYSAPVA--------AEPFLSGTSSNYVEEMYCAWLENP 69
Query: 90 SSVDESWDNFFRNFVGQASTSPGISGQT----------------------------IQES 121
SV +SWD FFRN A PG + Q+ +++
Sbjct: 70 KSVHKSWDIFFRNT--NAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDH 127
Query: 122 MRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDP---------GLYGFTEADLDREFF 172
+ + L+RAYQ+ GH A+LDPLG+ + ++ + G YG E+DLD+ F
Sbjct: 128 LAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFH 187
Query: 173 LGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPT 232
L + F+ LR I+ RLE AYC IG E+M I D ++C W+R K ETP
Sbjct: 188 LPT---TTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIM 244
Query: 233 QFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVEN 292
QF+ E + + RL ST FE FL KW+S KRFGLEG E LIP +K + D++S+ GV+
Sbjct: 245 QFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDY 304
Query: 293 IVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKYHLGTSYDRPTR 352
++MGM HRGRLNVL NV+RK L QIFC+F L + G+GDVKYHLG + R R
Sbjct: 305 VIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD----EGSGDVKYHLGMYHRRINR 360
Query: 353 -GGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVV 411
R I LSL+ANPSHLEA +P+V+GKT+A+Q+Y D E K M +L+HGD +FAGQG+V
Sbjct: 361 VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV 420
Query: 412 YETLHLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDV 471
YET HLS LP+YTT GT+H+V NNQ+ FTTDP RSS Y TDVA+ +NAPIFHVN DD
Sbjct: 421 YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDP 480
Query: 472 ESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIY 531
E+V++VC++AAEWR TFH DVVVDLVCYRR GHNE+DEP FTQP MYK IR L+ Y
Sbjct: 481 EAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKY 540
Query: 532 QKKLLELGELTQEDIDKIHKKVTSILNDEFLASKD-YIPKRRDWLSAYWSGF----KSPE 586
+ L+ G + Q + ++ K I + F SKD I + WL + W GF P
Sbjct: 541 AELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPR 600
Query: 587 QLSRIRNTGVKPDILKNVGKAITALP-ESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEA 645
+S +TG+ DIL ++G +++P E+ H + ++ + R +MV+ +DW AE
Sbjct: 601 SMS-CPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVK-NRTVDWALAEY 658
Query: 646 LAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYC-PLDHVIMNQNEEMFTVS 704
+AF +L+ EG H+RLSGQDVERGTFSHRH V+HDQ ++ C P++H+ NQ +TV
Sbjct: 659 MAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQ--APYTVC 716
Query: 705 NSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLV 764
NSSLSE+GVLGFE G M +PN+LV+WEAQFGDF N AQ I D F+ G++KW+RQ G+V
Sbjct: 717 NSSLSEYGVLGFEAGLRMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIV 776
Query: 765 VLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTL--RKQIQECNLQIVNVTTPA 822
+LLPHG +G GPEHSS R ER+LQM +D P ++P++ Q+ +CN +VN +TP
Sbjct: 777 LLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPG 836
Query: 823 NFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIK 882
NFFHVLRRQI FRKPLI+ +PK+LLR RS+ E GT F+R+I
Sbjct: 837 NFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEM----------LPGTHFQRVIP 886
Query: 883 DQNDHSNVEEGIRRLILCSGKVYYELD-EQRTKDDAKDVAICRVEQLCPFPYDLVQRELK 941
+ + E ++RL+ C+GKVYY+L E++ +D VAI R+EQL PFP+DL+ +E++
Sbjct: 887 EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQ 946
Query: 942 RYPNAEVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKV 1001
+YPNAE+ WCQEE N G Y Y+ PRL T++ + V Y GR P+AA ATG K
Sbjct: 947 KYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRA-----KPVWYAGRNPAAAPATGNKKT 1001
Query: 1002 H 1002
H
Sbjct: 1002 H 1002
>ODO1_MOUSE (Q60597) 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor (EC 1.2.4.2) (Alpha-ketoglutarate
dehydrogenase)
Length = 1019
Score = 879 bits (2271), Expect = 0.0
Identities = 478/1019 (46%), Positives = 639/1019 (61%), Gaps = 82/1019 (8%)
Query: 30 TRTTNLPSTSRKLHTTIFKSEAHAAPVPRPVPLSRLTDNFLDGTSSAYLEELQRAWEADP 89
T + N P+ R T + ++APV + FL GTSS Y+EE+ AW +P
Sbjct: 22 TFSQNKPAAIR----TFQQIRCYSAPVA--------AEPFLSGTSSNYVEEMYCAWLENP 69
Query: 90 SSVDESWDNFFRNFVGQASTSPGISGQT----------------------------IQES 121
SV +SWD FFRN A PG + Q+ +++
Sbjct: 70 KSVHKSWDIFFRNT--NAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDH 127
Query: 122 MRLLLLVRAYQVNGHMKAKLDPLGLKERNIPD-----ELDPGLYGFTEADLDREFFLGVW 176
+ + L+RAYQV GH AKLDPLG+ N D + G YG E+DLD+ F L
Sbjct: 128 LAVQSLIRAYQVRGHHIAKLDPLGISCVNFDDAPVTVSSNVGFYGLHESDLDKVFHLPT- 186
Query: 177 NMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPTQFSR 236
+ F+ P LR I+ RLE AYC IG E+M I D ++C W+R K ETP QF+
Sbjct: 187 --TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTN 244
Query: 237 ERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVENIVMG 296
E + + RL ST FE FL KW+S KRFGLEG E LIP +K + D +S GV+ ++MG
Sbjct: 245 EEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMG 304
Query: 297 MAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKYHLGTSYDRPTR-GGR 355
M HRGRLNVL NV+RK L QIFC+F L + G+GD+KYHLG + R R R
Sbjct: 305 MPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD----EGSGDMKYHLGMYHRRINRVTDR 360
Query: 356 RIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETL 415
I LSL+ANPSHLEA +P+V+GKT+A+Q+Y D E K M +L+HGD +FA QG+VYET
Sbjct: 361 NITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAVQGIVYETF 420
Query: 416 HLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVV 475
HLS LP+YTT GT+H+V NNQ+ FTTDP RSS Y TDVA+ +NAPIFHVN DD E+V+
Sbjct: 421 HLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVM 480
Query: 476 HVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQKKL 535
+VC++AAEWR TFH DVVVDLVCYRR GHNE+DEP FTQP MYK IR L+ Y + L
Sbjct: 481 YVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELL 540
Query: 536 LELGELTQEDIDKIHKKVTSILNDEFLASKD-YIPKRRDWLSAYWSGFKSPEQLSR---I 591
+ G + Q + ++ K I + F SKD I + WL + W GF + + R
Sbjct: 541 VSQGFVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFTLDGQPRSMTC 600
Query: 592 RNTGVKPDILKNVGKAITALP-ESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEALAFAT 650
+TG++ D+L ++GK +++P E+ H + ++ + R ++V T +DW AE +AF +
Sbjct: 601 PSTGLEEDVLFHIGKVASSVPVENFTIHGGLSRILKTRRELV-TNRTVDWALAEYMAFGS 659
Query: 651 LIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYC-PLDHVIMNQNEEMFTVSNSSLS 709
L+ EG HVRLSGQDVERGTFSHRH V+HDQ ++ C P++H+ NQ +TV NSSLS
Sbjct: 660 LLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQ--APYTVCNSSLS 717
Query: 710 EFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLVVLLPH 769
E+GVLGFELG++M +PN+LV+WEAQFGDF N AQ I D F+ G++KW+RQ G+V+LLPH
Sbjct: 718 EYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPH 777
Query: 770 GYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTL--RKQIQECNLQIVNVTTPANFFHV 827
G +G GPEHSS R ER+LQM +D P ++P++ Q+ +CN +VN +TP NFFHV
Sbjct: 778 GMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHV 837
Query: 828 LRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDH 887
LRRQI FRKPLIV +PK+LLR R++ E GT F+R+I +
Sbjct: 838 LRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEM----------LPGTHFQRVIPENGPA 887
Query: 888 SNVEEGIRRLILCSGKVYYELD-EQRTKDDAKDVAICRVEQLCPFPYDLVQRELKRYPNA 946
+ ++RL+ C+GKVYY+L E++ ++ ++VAI R+EQL PFP+DL+ +E ++YPNA
Sbjct: 888 AQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPNA 947
Query: 947 EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKVHQRE 1005
E+ WCQEE N G Y Y+ PRL T++ + V Y GR P+AA ATG K H E
Sbjct: 948 ELAWCQEEHKNQGYYDYVKPRLRTTIDRA-----KPVWYAGRDPAAAPATGNKKTHLTE 1001
>ODO1_COXBU (P51056) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 934
Score = 720 bits (1858), Expect = 0.0
Identities = 418/979 (42%), Positives = 586/979 (59%), Gaps = 87/979 (8%)
Query: 67 DNFLDGTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSPGISGQTIQESMRLL- 125
+++L ++ Y+E L + DP SV+E W ++FR AST P IS TI+E R L
Sbjct: 12 NSYLADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGAST-PDISHATIREEFRELA 70
Query: 126 ---------------------LLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYGFTE 164
LL+ Y+ GH+ AK++PLG R + L+ G Y TE
Sbjct: 71 RKPRSISPTAITPAAEQAAVDLLIEGYRRFGHLNAKINPLG-DNRPVDSRLELGHYNLTE 129
Query: 165 ADLDREFFLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRD 224
+D ++ F G L N+P TL+ I TRL + YCGSIG +Y I D + NWLRD
Sbjct: 130 SDFNKTFAT-----YGLL--NKPKATLKEIYTRLREIYCGSIGVQYSTISDERERNWLRD 182
Query: 225 KIETPSPT-QFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFD 283
+E P+ +F +E + I +L + E +L TK+ R+ LEGG++LIP + E+
Sbjct: 183 YVEQRLPSIEFDKETKRNILQQLVTAESLEKYLDTKYVGQVRYSLEGGDSLIPLLDELTK 242
Query: 284 RASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKYHL 343
RA +E IV+ MAHRGR+NVL N++ + ++F EF G + + GL +G DVKYH
Sbjct: 243 RARHQKIEEIVICMAHRGRVNVLLNIMGQSAAELFQEFEG---KKDYGLMSG--DVKYHR 297
Query: 344 GTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDG 403
G S D T G IHLSL NPSHLE + P+ +G RA+Q N +R M V+IHGD
Sbjct: 298 GYSRDVKTDAGP-IHLSLAFNPSHLEFICPVAMGSVRARQERQNGHKRDYAMTVMIHGDA 356
Query: 404 SFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKALNAP 462
SF+G+G+V E L +S + GG+IHI+ NNQV FTT +P RSS Y +D+AK L+AP
Sbjct: 357 SFSGEGIVMEALSMSQTRAHHVGGSIHIILNNQVGFTTSNPHDARSSMYCSDIAKMLDAP 416
Query: 463 IFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIR 522
+FHVNGDD E+VV V +LA ++R FH DV +DLVCYRR GH E+D+P TQP MYKVI+
Sbjct: 417 VFHVNGDDPEAVVAVTQLALDYRMAFHKDVFIDLVCYRRHGHQEVDDPMPTQPAMYKVIQ 476
Query: 523 NHPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGF 582
HP+ +Y K L+E T E++D + D + + + LSA+++
Sbjct: 477 EHPTTRTLYAKNLIEKKLCTAEEVD----QWIDDYRDRLDRGRQLVETLPEGLSAHYAAN 532
Query: 583 KSP---EQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDID 639
+P + + + +T + LK +GK + LP +L+ HR V+ +Y+ R +M E +D
Sbjct: 533 WTPYLGQDWTTLVDTTLPLKKLKALGKKFSTLPNTLHLHRKVEAIYKARLEMAEGKTPMD 592
Query: 640 WGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEE 699
WGFAE LA+A+L+ EG VRL GQD RGTF HRHAVV DQ TG++Y PL H ++ +
Sbjct: 593 WGFAEMLAYASLLEEGFSVRLVGQDSRRGTFFHRHAVVFDQETGKEYEPLKH--LSDKQA 650
Query: 700 MFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLR 759
+ +S L E G LGFE GYS +PNSLVIWEAQFGDFAN AQVI D F+SSG KW R
Sbjct: 651 APHIYDSLLCEAGALGFEYGYSTADPNSLVIWEAQFGDFANVAQVIVDQFISSGWQKWNR 710
Query: 760 QTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVT 819
+G+V+ LPHGY+G+GPEHSS RLERYLQ+ + N+Q+ T
Sbjct: 711 LSGIVLFLPHGYEGKGPEHSSARLERYLQLCAQN------------------NMQVCAPT 752
Query: 820 TPANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKR 879
TP+ FH+LRRQ+ R +RKPL+V++PK++LR+K+ S+L D + K
Sbjct: 753 TPSQIFHLLRRQVLRPYRKPLVVLTPKSVLRNKLAVSSLE-----------DLARGQLKL 801
Query: 880 LIKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAK--DVAICRVEQLCPFPYDLVQ 937
LI + H + I R+ILCSGKVYY+L +R + K +A+ R+EQL PFPYD ++
Sbjct: 802 LIPEIEKHD--PKKITRVILCSGKVYYDLLAKRREHKGKLNHIAMIRIEQLYPFPYDELK 859
Query: 938 RELKRYPNA-EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATAT 996
EL++YPNA +V+WCQEEP N G + RLI M+ + ++YVGR+ AA A
Sbjct: 860 AELEKYPNAKQVIWCQEEPKNQGAWFCTRHRLIKCMR-----DDQTLEYVGRSAFAAPAA 914
Query: 997 GFLKVHQREQAELVHKAMQ 1015
G+ ++ + Q +LV++A++
Sbjct: 915 GYSALYVKLQEQLVNQALE 933
>ODO1_ALCEU (Q59106) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 950
Score = 706 bits (1822), Expect = 0.0
Identities = 410/985 (41%), Positives = 573/985 (57%), Gaps = 89/985 (9%)
Query: 66 TDNFLDGTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSPGISGQTI------- 118
++++L G ++ Y+EEL A+ +P+SV ++W +F + + G +G+ I
Sbjct: 7 SNSYLFGGNAPYVEELYEAYLQNPASVPDNWRAYF-DAMQNVPAVDGSNGRDIPHAPIVA 65
Query: 119 -------QESMRLLL----------------LVRAYQVNGHMKAKLDPLGLKERNIPDEL 155
Q +R ++ L+ AY+ G A LDPL +ER +L
Sbjct: 66 SFAERAKQGPIRTIVASADSDMGRKRVAATQLIAAYRNIGSHWADLDPLKRQERPPLPDL 125
Query: 156 DPGLYGFTEADLDREFFLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPD 215
DP YGF+EADLD V+N S + +LR +L L + YCG+IG+E+M++ D
Sbjct: 126 DPAFYGFSEADLDI-----VFNASNTYF-GKESMSLRELLNNLRETYCGTIGFEFMYVSD 179
Query: 216 RDKCNWLRDKIETP-SPTQFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETL 274
+ + W ++++ET S F+ E+++ I DRL + E FL TK+ KRF LEGGE+
Sbjct: 180 QAQKRWWQERLETTRSKPVFTLEKKKHILDRLTAAEGLERFLHTKYVGQKRFSLEGGESF 239
Query: 275 IPGMKEMFDRASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYT 334
I M E+ A GV+ IV+GMAHRGRLNVL N + K +F EF G D
Sbjct: 240 IAAMDELIQHAGSKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDD-----L 294
Query: 335 GTGDVKYHLGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKN 394
GDVKYH G S D T GG +HLSL NPSHLE VNP+V G +A+Q + +
Sbjct: 295 PAGDVKYHKGFSSDVSTEGGP-VHLSLAFNPSHLEIVNPVVEGSAKARQERRGEVGHKEV 353
Query: 395 MGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYST 453
+ V +HGD +FAGQGVV ETL+L+ Y TGG++HIV NNQ+ FTT DP RS+ Y T
Sbjct: 354 LPVQVHGDAAFAGQGVVMETLNLAQTRGYGTGGSMHIVINNQIGFTTSDPRDARSTLYCT 413
Query: 454 DVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFT 513
DV K + AP+ HVNGDD E+VV+ +LA ++R F DVVVD++C+R+ GHNE D P+ T
Sbjct: 414 DVVKMIEAPVLHVNGDDPEAVVYAMQLAVDFRMEFKKDVVVDIICFRKLGHNEQDTPAVT 473
Query: 514 QPKMYKVIRNHPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRD 573
QP MYK I HP ++Y KL + E D+ K + ++ + + ++
Sbjct: 474 QPLMYKKIAQHPGTRKLYADKLAAQNLVPAEFGDEKVKAYRAAMDAGKHTADPVLSNFKN 533
Query: 574 WLSAYWSGFKSPEQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVE 633
+ W F + + + +T V LK + + IT PE+L H V+KV + RA M
Sbjct: 534 KFAVDWMPFLN-RKWTDAADTAVPVTELKRLAERITTTPETLKLHPLVEKVVKDRANMGR 592
Query: 634 TGEDIDWGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGE----KYCPL 689
+ +DWG E LAFA+L+ G VR++ QD RGTF+HRHAV+HDQA Y PL
Sbjct: 593 GDQPLDWGMGEHLAFASLVSSGYPVRITAQDAGRGTFTHRHAVLHDQARERWDAGSYVPL 652
Query: 690 DHVIMNQNEEMFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNF 749
+V ++N+ FTV +S LSE VLGFE GYS PN+LVIWEAQFGDF NGAQV+ D F
Sbjct: 653 QNV--SENQAPFTVIDSVLSEEAVLGFEYGYSAAEPNALVIWEAQFGDFVNGAQVVIDQF 710
Query: 750 LSSGESKWLRQTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQ 809
+SSGE KW R +GL ++LPHGY+GQGPEHSS R+ER+LQ+ DH
Sbjct: 711 ISSGEVKWGRASGLTLMLPHGYEGQGPEHSSARIERFLQLCADH---------------- 754
Query: 810 ECNLQIVNVTTPANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPG 869
N+Q+ TTPA FH+LRRQ+ R FRKPL++M+PK+LLR+K S LS D +GH
Sbjct: 755 --NMQVCQPTTPAQIFHLLRRQMIRLFRKPLVIMTPKSLLRNKDAVSPLS--DLAKGH-- 808
Query: 870 FDKQGTRFKRLIKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLC 929
F+ +I D + + ++R+I+CSGKVYY+L R + +A D A+ R+EQL
Sbjct: 809 -------FETVIPDHEELN--ASKVKRVIMCSGKVYYDLVNTRKEREANDTAVIRLEQLY 859
Query: 930 PFPYDLVQRELKRYPNA-EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGR 988
PFP+ V ELK+YPNA E+VWCQ+EP N G + ++ ++ +M + + Y GR
Sbjct: 860 PFPHKAVAAELKKYPNATEIVWCQDEPQNQGAWFFVQHYIMENMT-----DGQKLGYAGR 914
Query: 989 APSAATATGFLKVHQREQAELVHKA 1013
SA+ A G+ H +Q L+ A
Sbjct: 915 PASASPAVGYYAKHNEQQKALLEAA 939
>ODO1_RICCN (Q92J42) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 928
Score = 705 bits (1820), Expect = 0.0
Identities = 404/973 (41%), Positives = 575/973 (58%), Gaps = 83/973 (8%)
Query: 69 FLDGTSSAYLEELQRAWEADPSSVDESWDNFF-----RNFVGQASTSPGISGQTIQE--- 120
+L G ++ ++EEL + + A+P+SVD++W FF N + ST+ I I++
Sbjct: 10 YLFGGNAVFVEELYKQYLANPASVDQTWQEFFAGIKDNNTLLNKSTAKIIIPDEIKKESL 69
Query: 121 ----------SMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGL--YGFTEADLD 168
S++ ++ AY+ + H A LDPLGL+ R ++L + +G L+
Sbjct: 70 NNNLSSEDLNSLKAKEMINAYRKHAHYLANLDPLGLELRKTKNDLKLNIETFGLDSGQLE 129
Query: 169 REF-----FLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLR 223
F+G WN L ++T+ ++ Y GSIG E+ I + NWL
Sbjct: 130 ENINITDEFVGTWNCK-----------LSELVTKFDKVYTGSIGVEFEQIENVAGKNWLY 178
Query: 224 DKIETPSPTQFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFD 283
+K+E S FS E ++ I + L FE +L TK+ AKRF +EGG+ I M + D
Sbjct: 179 NKLE--SEVTFSSEDKKTILNDLVEVEGFEQYLHTKFPGAKRFSIEGGDASIVAMSKAID 236
Query: 284 RASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEF-SGGLPQDEVGLYTGTGDVKYH 342
+ GV IV+GMAHRGRLN L VV KP + + +F SG + DE+ + +GDVKYH
Sbjct: 237 LSMHQGVSEIVIGMAHRGRLNTLTKVVGKPYKAVIADFISGSVFPDELNV---SGDVKYH 293
Query: 343 LGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGD 402
LG S DR T ++IHLSL NPSHLEAVNP+V GK RAKQ D +R K +L+HGD
Sbjct: 294 LGYSSDR-TLEDKKIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTKRSKVKAILVHGD 352
Query: 403 GSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAP 462
+F GQGVV E+L +S L Y GG +H V NNQ+ FT + R+S+YST+ AK + AP
Sbjct: 353 AAFCGQGVVAESLSMSPLAAYDIGGILHFVINNQLGFTANAADTRASRYSTEFAKIIAAP 412
Query: 463 IFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIR 522
I HVNGDD+E+V+ +A E+RQ F DVVV+++CYR++GHNE DEP +TQ KMY +I+
Sbjct: 413 ILHVNGDDIEAVLKATNIAVEYRQKFGKDVVVEIICYRKYGHNEGDEPMYTQGKMYNIIK 472
Query: 523 NHPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGF 582
N + IY +L++ G + K+ ++ + L+ E+ +K Y + +L W G
Sbjct: 473 NKLTPGNIYANELVKSGVIDNNYFAKLKEEFKAKLDKEYEQAKSY-KQEAHFLGGLWQGI 531
Query: 583 KSPEQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDWGF 642
+ I TG+ L ++G + +P+ + + K++E R + + IDW
Sbjct: 532 SRTRTQATI--TGISKKTLHDLGTKLCEIPKDFAVNPKLVKLFEARKATLTADQPIDWAT 589
Query: 643 AEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEMFT 702
AE LAFA+L+ G ++RL+GQD RGTFSHRH+V+H+Q G Y PL++ +++ + +
Sbjct: 590 AEQLAFASLLASGTNIRLTGQDSGRGTFSHRHSVLHNQIDGTTYIPLNN--LSKEQAKYE 647
Query: 703 VSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTG 762
V++S+LSE+ VLGFE GYS+ NP +LV+WEAQFGDFANGAQ+IFD F+SS E+KWLR +G
Sbjct: 648 VADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSG 707
Query: 763 LVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTTPA 822
LVVLLPH ++GQGPEHSS RLER+LQ+A E N+ + TTPA
Sbjct: 708 LVVLLPHAFEGQGPEHSSARLERFLQLA------------------AENNMYVTYPTTPA 749
Query: 823 NFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIK 882
+ FH+LRRQI + RKPLIVMSPK+LLR K S L E + T F ++
Sbjct: 750 SIFHLLRRQILDDTRKPLIVMSPKSLLRHKYAVSKLDELG----------ENTTFLPVLD 799
Query: 883 DQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRELKR 942
+ I ++ILCSGKVYY+L E R + ++AI R+EQL PF LV LK+
Sbjct: 800 EVTKVDT--NNITKVILCSGKVYYDLFEMRGNN--SNIAIIRLEQLYPFEKKLVASLLKK 855
Query: 943 YPNA-EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKV 1001
Y E +WCQEEP NMG + YI+ L ++K G + KYVGR SA+ A G L+V
Sbjct: 856 YNRTQEFIWCQEEPKNMGTWCYIVSHLNDALKEAGI--KNEFKYVGREESASPAVGSLQV 913
Query: 1002 HQREQAELVHKAM 1014
H ++Q +L+ A+
Sbjct: 914 HNKQQEKLLRTAL 926
>ODO1_ECOLI (P07015) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 933
Score = 702 bits (1813), Expect = 0.0
Identities = 406/975 (41%), Positives = 560/975 (56%), Gaps = 79/975 (8%)
Query: 65 LTDNFLDGTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSPGISGQTIQ----- 119
L ++L G + +++E+L + DP SVD +W + F+ G QT +
Sbjct: 10 LDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRL 69
Query: 120 ------------------ESMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYG 161
+ +++L L+ AY+ GH A LDPLGL +++ +LDP +
Sbjct: 70 AKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHD 129
Query: 162 FTEADLDREFFLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNW 221
TEAD F N+ F S + L +L L+Q YCG IG EYMHI ++ W
Sbjct: 130 LTEADFQETF-----NVGSFAS-GKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRW 183
Query: 222 LRDKIETPSPTQFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEM 281
++ +IE+ T S E++ + + A L E +L K+ AKRF LEGG+ LIP +KEM
Sbjct: 184 IQQRIESGRATFNSEEKKRFLSELTAAEGL-ERYLGAKFPGAKRFSLEGGDALIPMLKEM 242
Query: 282 FDRASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKY 341
A + G +V+GMAHRGRLNVL NV+ K + +F EF+G + + GTGDVKY
Sbjct: 243 IRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKE-----HLGTGDVKY 297
Query: 342 HLGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHG 401
H+G S D T GG +HL+L NPSHLE V+P+V+G RA+ ++ K + + IHG
Sbjct: 298 HMGFSSDFQTDGGL-VHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHG 356
Query: 402 DGSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKALN 460
D + GQGVV ETL++S Y GGT+ IV NNQV FTT +P RS+ Y TD+ K +
Sbjct: 357 DAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQ 416
Query: 461 APIFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKV 520
APIFHVN DD E+V V LA ++R TF DV +DLVCYRR GHNE DEPS TQP MY+
Sbjct: 417 APIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQK 476
Query: 521 IRNHPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWS 580
I+ HP+ +IY KL + T ED ++ L+ ++ P S WS
Sbjct: 477 IKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMH--SFTWS 534
Query: 581 GFKSPEQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDW 640
+ + E N V+ L+ + K I+ +PE++ V K+Y R M + DW
Sbjct: 535 PYLNHEWDEEYPNK-VEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDW 593
Query: 641 GFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEM 700
G AE LA+ATL+ EG VRLSG+D RGTF HRHAV+H+Q+ G Y PL H+ + +
Sbjct: 594 GGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHI--HNGQGA 651
Query: 701 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQ 760
F V +S LSE VL FE GY+ P +L IWEAQFGDFANGAQV+ D F+SSGE KW R
Sbjct: 652 FRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRM 711
Query: 761 TGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTT 820
GLV+LLPHGY+GQGPEHSS RLERYLQ+ E N+Q+ +T
Sbjct: 712 CGLVMLLPHGYEGQGPEHSSARLERYLQLC------------------AEQNMQVCVPST 753
Query: 821 PANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRL 880
PA +H+LRRQ R R+PL+VMSPK+LLR + S+L E + P +
Sbjct: 754 PAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGE-------- 805
Query: 881 IKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQREL 940
D+ D +G++R+++CSGKVYY+L EQR K++ DVAI R+EQL PFP+ +Q L
Sbjct: 806 -IDELD----PKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVL 860
Query: 941 KRYPNA-EVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFL 999
+++ + + VWCQEEP+N G + Y + G ++Y GR SA+ A G++
Sbjct: 861 QQFAHVKDFVWCQEEPLNQGAW-YCSQHHFREVIPFG----ASLRYAGRPASASPAVGYM 915
Query: 1000 KVHQREQAELVHKAM 1014
VHQ++Q +LV+ A+
Sbjct: 916 SVHQKQQQDLVNDAL 930
>ODO1_RICPR (Q9ZDY3) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 936
Score = 701 bits (1810), Expect = 0.0
Identities = 405/979 (41%), Positives = 578/979 (58%), Gaps = 95/979 (9%)
Query: 69 FLDGTSSAYLEELQRAWEADPSSVDESWDNFF-----RNFVGQASTSPGISGQTIQE--- 120
+L ++ ++EEL R + A+P+SVD++W FF N V ST+ IS +
Sbjct: 10 YLFSGNAVFVEELYRQYLANPNSVDQTWQEFFADIKDNNVVLNKSTAKVISTNVTNKELL 69
Query: 121 ----------SMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGL--YGFTEADLD 168
+++ ++ AY+ N H A LDPLGL+ R ++L + +G + L
Sbjct: 70 NNNLSSETLNNLKAKEMISAYRRNAHYLANLDPLGLEIRKTKNDLKLNIEAFGLDSSQLG 129
Query: 169 REF-----FLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLR 223
F+G WN L ++T+L++ Y SIG E+ I + ++ NWL
Sbjct: 130 ENINIMDEFIGTWNCK-----------LSELVTKLDKVYTSSIGVEFDQIENVEEKNWLY 178
Query: 224 DKIETPSPTQFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFD 283
K+ET F+ E ++ I + L FE FL K+ AKRF +EGG+ I M + D
Sbjct: 179 TKLETD--ITFTSEEKKSILNDLVEVECFEQFLHIKFPGAKRFSIEGGDASIVAMNKAID 236
Query: 284 RASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEF-SGGLPQDEVGLYTGTGDVKYH 342
+ GVE IV+GMAHRGRLN L VV KP +++ F +G + D + + +GDVKYH
Sbjct: 237 LSMHQGVEEIVIGMAHRGRLNTLTKVVGKPYKEVIASFINGNIFPDGLNV---SGDVKYH 293
Query: 343 LGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGD 402
LG S DR R ++IHLSL NPSHLEA+N +V GK RAKQ D +R K +L+HGD
Sbjct: 294 LGYSADR-VRANQKIHLSLADNPSHLEAINSIVAGKVRAKQDIFVDTKRSKIKAILVHGD 352
Query: 403 GSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAP 462
+F GQGVV E+L +S L Y GG +H V NNQ+ FT + R+S+YST+ AK ++AP
Sbjct: 353 AAFCGQGVVAESLSMSPLTAYNVGGILHFVINNQLGFTANAADTRASRYSTEFAKIISAP 412
Query: 463 IFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIR 522
I HVNGDD+E+V+ ++A E+RQ F DVVV+++CYR++GHNE DEP +TQ KMY +I+
Sbjct: 413 ILHVNGDDIEAVLKATDIAVEYRQKFSKDVVVEIICYRKYGHNEGDEPMYTQSKMYNIIK 472
Query: 523 NHPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGF 582
+ P+ IY +L++ G + K+ +K L+ E+ +K Y + + YW G
Sbjct: 473 SKPTPGSIYANELVKNGIIDNNYYAKLKEKFKIRLDQEYEQAKSY-KQETHFFEGYWKG- 530
Query: 583 KSPEQLSRIRN----TGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDI 638
+SRIR TGV IL+++G + +P+ + + +++E R + T + I
Sbjct: 531 -----ISRIRGKDAITGVNKKILQDLGTKLCEIPKDFAINPKLIRLFEVRKTTLTTDQPI 585
Query: 639 DWGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNE 698
DW AE LAFA L+ G ++RL+GQD RGTFSHRH+++H+Q Y PL++ +++ +
Sbjct: 586 DWATAEQLAFAHLLCSGINIRLTGQDSARGTFSHRHSILHNQIDDTTYIPLNN--LSKTQ 643
Query: 699 EMFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWL 758
+ V+NS+LSE+ LGFE GYS+ NP +LV+WEAQFGDFANGAQ+IFD F+SS +KWL
Sbjct: 644 AKYEVANSNLSEYAALGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSATKWL 703
Query: 759 RQTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNV 818
R +GLVVLLPH ++GQGPEHSS RLER+LQ+A E N+ I
Sbjct: 704 RMSGLVVLLPHAFEGQGPEHSSARLERFLQLA------------------AEENMYITYP 745
Query: 819 TTPANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFK 878
TTPA+ FH+LRRQI RKPLIVMSPK+LLR K S L E + T F
Sbjct: 746 TTPASIFHLLRRQILESTRKPLIVMSPKSLLRHKYAVSKLDELG----------ENTTFI 795
Query: 879 RLIKD--QNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLV 936
++ + + D +NV ++ILCSGKVYY+L RT + ++ I R+EQL PF LV
Sbjct: 796 PILDEVTKIDTNNV----TKVILCSGKVYYDLFAMRTNN--SNIVIIRLEQLYPFEKKLV 849
Query: 937 QRELKRYPNAEV-VWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATA 995
LK+Y A+ +WCQEEP NMG + YI L ++K + KYVGR SA+ A
Sbjct: 850 ASLLKKYNKAQAFIWCQEEPKNMGAWHYIATHLNDALKEAEIN--NEFKYVGREESASPA 907
Query: 996 TGFLKVHQREQAELVHKAM 1014
G L+VH ++Q +L+ +A+
Sbjct: 908 VGSLQVHNKQQEKLLMEAL 926
>ODO1_AZOVI (P20707) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 943
Score = 694 bits (1791), Expect = 0.0
Identities = 403/978 (41%), Positives = 566/978 (57%), Gaps = 86/978 (8%)
Query: 70 LDGTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSP------------------ 111
L G ++AY+EEL + DP++V E W +F +A TS
Sbjct: 15 LSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLPAEAGTSTDVPHAPVRDQFVLLAKNQ 74
Query: 112 ---------GISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYGF 162
+S + ++ + +L L++AY+ GH ++LDPLGL +R P +L YG
Sbjct: 75 RRAQPVATSSVSTEHEKKQVEVLRLIQAYRTRGHQASQLDPLGLWQRTAPSDLSITHYGL 134
Query: 163 TEADLDREFFLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWL 222
T ADLD F +G L + TLR IL L++ YC +IG E+ HI D ++ NW
Sbjct: 135 TNADLDTPF------RTGELYIGKEEATLREILQALQETYCRTIGAEFTHIVDSEQRNWF 188
Query: 223 RDKIETPSPTQ-FSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEM 281
++E+ +S+E + + +RL+ + E +L TK+ KRFGLEGGE+L+P + E+
Sbjct: 189 AQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPGTKRFGLEGGESLVPVVDEI 248
Query: 282 FDRASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKY 341
R+ G + +V+GMAHRGRLN+L N + K R +F EF G + + G+GDVKY
Sbjct: 249 IQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFEG-----KHLVELGSGDVKY 303
Query: 342 HLGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHG 401
H G S + T GG +HL++ NPSHLE V+P+V G RA+Q DA K + + IHG
Sbjct: 304 HQGFSSNVMTSGGE-VHLAMAFNPSHLEIVSPVVEGSVRARQDRRVDATGEKVVPISIHG 362
Query: 402 DGSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKALN 460
D +FAGQGVV ET +S + Y TGGTIHIV NNQV FTT +P RS++Y TD AK +
Sbjct: 363 DSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVDTRSTEYCTDPAKMIQ 422
Query: 461 APIFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKV 520
AP+ HVNGDD E+V+ V +LA ++R F DVV+DLVCYRR GHNE DEPS TQP MY+
Sbjct: 423 APVLHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMYQK 482
Query: 521 IRNHPSALEIYQKKLLELGELTQEDID-KIHKKVTSILNDEFLASKDYIPKRRDWLSAYW 579
I P+ E+Y L++ G L+QE++ K+ + T++ N + + K + + L W
Sbjct: 483 IAKQPTTRELYADALVKEGSLSQEEVQAKVDEYRTALDNGQHVL-KSLVKEPNTELFVDW 541
Query: 580 SGFKSPEQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDID 639
+ + +R +T + L+ + + +PE R V K+ E R +M I+
Sbjct: 542 TPYLGHAWTAR-HDTSFELKTLQELNAKLLQIPEGFVVQRQVAKILEDRGRMGVGAMPIN 600
Query: 640 WGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEE 699
WG AE LA+ATL+ EG+ VR++GQDV RGTFSHRHA +H+Q +Y PL ++ Q +
Sbjct: 601 WGCAETLAYATLLKEGHPVRITGQDVGRGTFSHRHAALHNQKDASRYIPLQNLYEGQPK- 659
Query: 700 MFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLR 759
F + +S LSE VL FE GY+ PN+LVIWEA GDFANGAQV+ D F+SSGE+KW
Sbjct: 660 -FELYDSFLSEEAVLAFEYGYATTTPNALVIWEASSGDFANGAQVVIDQFISSGETKWGA 718
Query: 760 QTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVT 819
GL +LLPHGY+GQGPEHSS RLERYLQ+ E N+Q+ T
Sbjct: 719 LCGLTMLLPHGYEGQGPEHSSARLERYLQLC------------------AEQNIQVCVPT 760
Query: 820 TPANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKR 879
TPA +H+LRRQ+ R RKPL+ ++PK+LLR K S L + HP +
Sbjct: 761 TPAQVYHMLRRQVIRPLRKPLVALTPKSLLRHKSAISTLEDLALGSFHPVLPE------- 813
Query: 880 LIKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRE 939
D D VE RL+LCSGKVYY+L ++R + +D+AI R+EQL PFP + +
Sbjct: 814 --VDSLDPKKVE----RLVLCSGKVYYDLLDKRHAEGREDIAIVRIEQLYPFPEEELAEV 867
Query: 940 LKRYPNAE-VVWCQEEPMNMGGY---SYILPRLITSMKALGRGGYEDVKYVGRAPSAATA 995
+ Y N + VVWCQEEPMN G + + + R+ ++ K ++Y GR SAA A
Sbjct: 868 MAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRVASAHKK-----ELFLQYAGREASAAPA 922
Query: 996 TGFLKVHQREQAELVHKA 1013
G+ +H +Q +L+ A
Sbjct: 923 CGYASMHAEQQEKLLQDA 940
>ODO1_HAEIN (P45303) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 935
Score = 686 bits (1770), Expect = 0.0
Identities = 396/988 (40%), Positives = 568/988 (57%), Gaps = 103/988 (10%)
Query: 65 LTDNFLDGTSSAYLEELQRAWEADPSSVDESWDNFF----------------RNFVGQAS 108
L L G + +Y+EEL ++ +DP SV+ESW F R++ + +
Sbjct: 11 LASTALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLA 70
Query: 109 TSPGISGQTI------QESMRLLLLVRAYQVNGHMKAKLDPLGLKERNIP--DELDPGLY 160
T+ + +++L + AY+ GH++A LDPL + ELD +
Sbjct: 71 RENHNEAVTVIDPAAGAKLVKVLQFINAYRFRGHLEANLDPLNYYRWKVSFVPELDYRHH 130
Query: 161 GFTEADLDREFFLGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCN 220
GFTE DL+ F N++ ++ + ++ L + L++ YCGSIG E+MH+ D ++
Sbjct: 131 GFTEQDLNETF-----NINHYVYKRDTIK-LGELAQMLKETYCGSIGLEFMHVQDMEQKM 184
Query: 221 WLRDKIET-PSPTQFSRERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMK 279
WL+ K+E+ F+ E R L + E +L K+ AKRF LEG + IP MK
Sbjct: 185 WLQSKMESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDAFIPLMK 244
Query: 280 EMFDRASDLGVENIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDV 339
E+ +S GV ++VMGMAHRGRLN+L NV+ K +F EF+G + TGDV
Sbjct: 245 EIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAGKHSSER------TGDV 298
Query: 340 KYHLGTSYDRPTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLI 399
KYH G S D +R+HL+L NPSHLE V+P+V+G R++Q ND E K + + +
Sbjct: 299 KYHQGFSSDFAV-DDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAITV 357
Query: 400 HGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKA 458
HGD + AGQGVV ETL++S Y+ GGTI IV NNQ+ FTT +P RS++Y TD+AK
Sbjct: 358 HGDSAVAGQGVVQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIAKM 417
Query: 459 LNAPIFHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMY 518
+ API HVNGDD E+V +A E+R F D+ +DL+ YRR GHNE DEP TQP MY
Sbjct: 418 IQAPIIHVNGDDPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPMMY 477
Query: 519 KVIRNHPSALEIYQKKLLELGELTQEDIDKIHK----------KVTSILNDEFLASKDYI 568
+I+ HP+ ++Y +L+ G +T+E + ++ +V S + A D++
Sbjct: 478 SIIKKHPTPRKVYADRLVSEGVMTEEQVTEMANDYRDALDNGDRVVSEWREMDTAKMDWL 537
Query: 569 P-KRRDWLSAYWSGFKSPEQLSRIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQ 627
DW + Y S F L+ + K + PESL H V+K+Y
Sbjct: 538 QYLNYDWTAPYESKFSQERFLT--------------LAKRVCEYPESLRAHPRVEKIYND 583
Query: 628 RAQMVETGEDIDWGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYC 687
R M + + +DWG AE +A+ATL+ EG +VRLSG+D RGTF HRHAVVH+Q G Y
Sbjct: 584 RKAMYQGEKLLDWGMAETMAYATLLDEGVNVRLSGEDAGRGTFFHRHAVVHNQNDGTGYV 643
Query: 688 PLDHVIMNQNEEMFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFD 747
PL H+ NQ F V +S LSE VL FE GY+ +P +L IWEAQFGDFANGAQ++ D
Sbjct: 644 PLTHLHANQGR--FEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQIVID 701
Query: 748 NFLSSGESKWLRQTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQ 807
F+SSGE KW R GLV+LLPHGY+GQGPEHSS RLERYLQ+
Sbjct: 702 QFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC----------------- 744
Query: 808 IQECNLQIVNVTTPANFFHVLRRQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGH 867
E N+Q+ +TPA +H+LRRQ R+ R+PLI +SPK+LLR + S+L E +
Sbjct: 745 -AEQNMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLDELIN---- 799
Query: 868 PGFDKQGTRFKRLIKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQ 927
GT F+ +I + ++ + ++R+++CSGKVYY+L EQR ++ KDVAI R+EQ
Sbjct: 800 ------GT-FQTVIGEIDELD--PKDVKRVVMCSGKVYYDLLEQRRANNQKDVAIIRIEQ 850
Query: 928 LCPFPYDLVQRELKRYPN-AEVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYV 986
L PFP++ V++ L+ Y + + VWCQEEP+N G + +++ + +KY
Sbjct: 851 LYPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIPESVK-----LKYA 905
Query: 987 GRAPSAATATGFLKVHQREQAELVHKAM 1014
GR SA+ A G++ +H ++Q +LV A+
Sbjct: 906 GRPASASPAVGYMSLHTKQQKQLVEDAL 933
>ODO1_BUCAP (Q8K9N3) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 923
Score = 647 bits (1668), Expect = 0.0
Identities = 377/969 (38%), Positives = 555/969 (56%), Gaps = 79/969 (8%)
Query: 68 NFLDGTSSAYLEELQRAWEADPSSVDESWDNFFRN---------------FVGQASTSPG 112
++L G + Y+E++ ++ +P SVD +W + F + + +
Sbjct: 13 SWLSGNNQNYIEKIYESYLINPKSVDITWQDKFSDLSKKRKNILKEEKFVYKNNSFKEIK 72
Query: 113 ISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYGFTEADLDREFF 172
I Q I E ++ ++ ++ G+ K+ +DPL L E+ L+P Y F+E +L +
Sbjct: 73 IDKQEILEK-KINYIINTFRKKGYKKSLIDPLKLNEQKKYKYLEPTFYHFSEDELKKTVK 131
Query: 173 LGVWNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPT 232
+ N S + + +R + +L YCGSIG+EYM+I + + W+ IE
Sbjct: 132 IDFKNSSQYEIK------IRDLYEQLNNKYCGSIGFEYMYIENSFEKKWITKHIELFFKE 185
Query: 233 QFSRERREVIF-DRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVE 291
++ ++ F + + FE +L K++ KRF LEGGETLI + E+ + V
Sbjct: 186 NLFIKKEKIRFLKEILYGETFEKYLGKKFSGTKRFSLEGGETLISILHEIIRYSKKNDVS 245
Query: 292 NIVMGMAHRGRLNVLGNVVRKPLRQIFCEFSG-GLPQDEVGLYTGTGDVKYHLGTSYDRP 350
I++GMAHRGRLNVL NV+ K + +F EFSG +P++ +GDVKYH+G +
Sbjct: 246 EIILGMAHRGRLNVLVNVLNKNPQVLFNEFSGINIPKEY------SGDVKYHMG-GITKI 298
Query: 351 TRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGV 410
++I+L L NPSHLE VNP+V+G RA +E K + + IHGD S GQGV
Sbjct: 299 KNDKKKIYLKLAYNPSHLEIVNPVVLGIARASINQLKISEN-KFLSINIHGDASIIGQGV 357
Query: 411 VYETLHLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKALNAPIFHVNGD 469
+ ETL++S Y GGTIHIV NNQ+ FTT +P++ RSS+Y TDVAK + AP+FHVN D
Sbjct: 358 IQETLNMSQTEAYKIGGTIHIVINNQIGFTTSNPKNLRSSKYCTDVAKMIQAPVFHVNAD 417
Query: 470 DVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALE 529
D+E+ + +LA ++++ F DV +DLVCYRR GHNE+D+P TQP MYK I NHP+ +
Sbjct: 418 DIEASIFAIQLALKFKKKFKKDVFIDLVCYRRHGHNEVDDPFVTQPIMYKKIHNHPTIGQ 477
Query: 530 IYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGFKSPEQLS 589
IY L+ +T DI+KI +K T+ + + K+ + + R+ + +G K+
Sbjct: 478 IYSNLLISEKLITSNDIEKIIEKYTT----KLVQGKNVLSQERN--ITFQNGNKNFFIKK 531
Query: 590 RIRNTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEALAFA 649
+ NT + +K++ +I +P S+ H VKK+Y++R M + +DWG AE LA+A
Sbjct: 532 QKENTQLNFLNIKDLLYSINTIPNSIEVHNRVKKIYQERIGMADGQILLDWGTAELLAYA 591
Query: 650 TLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEMFTVSNSSLS 709
T++ EG RLSG+D+ RGTF HRHA +HDQ G Y PL ++ NQ + F + +S LS
Sbjct: 592 TILKEGISCRLSGEDISRGTFFHRHAFIHDQNNGSIYVPLQNIEKNQGK--FEIWDSVLS 649
Query: 710 EFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLVVLLPH 769
E VL FE GYS+ N+L IWEAQFGDFANGAQV+ D F+SS E KW +++ LV+ LPH
Sbjct: 650 EEAVLAFEYGYSLFPSNNLTIWEAQFGDFANGAQVVIDQFISSSEQKWNQKSNLVLFLPH 709
Query: 770 GYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTTPANFFHVLR 829
GY+GQGPEHSS RLER+LQ+ E N+Q+ T + FH+LR
Sbjct: 710 GYEGQGPEHSSARLERFLQLC------------------AENNIQVCIPTVSSQIFHLLR 751
Query: 830 RQIHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSN 889
RQI KPLIV++PK+LLR+ V RS+L FK +I N+
Sbjct: 752 RQIFSNVYKPLIVLTPKSLLRNNVARSSLEVL-----------VNENFKNVI---NEIDK 797
Query: 890 VEEGIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRELKRYPNA-EV 948
++ ++R+I CSGK+YY+L E R K D +V + R+EQL PFP D + LK Y +
Sbjct: 798 NQKEVKRIIFCSGKIYYDLLEYRNKCDINNVLLIRIEQLYPFPKDEILTILKSYSYVQDF 857
Query: 949 VWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKVHQREQAE 1008
+WCQEEP N G + YI L T + + YV R +A+ A G + +H++EQ +
Sbjct: 858 IWCQEEPHNQGAWFYIKDLLSTLLPL-----NSHLNYVSRPSAASPAAGHILIHRKEQEK 912
Query: 1009 LVHKAMQHK 1017
L++ A K
Sbjct: 913 LINNAFNFK 921
>ODO1_BUCAI (P57388) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 909
Score = 631 bits (1628), Expect = e-180
Identities = 367/963 (38%), Positives = 563/963 (58%), Gaps = 79/963 (8%)
Query: 65 LTDNFLDGTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSPGISGQTIQESMRL 124
L ++L + Y+E + +++ + S+D+ W F F + + + + L
Sbjct: 10 LNSSWLSRENQNYIETIYKSFLTNAQSIDDMWHKAFLEFSEEQKNT--YERNNTKNNKYL 67
Query: 125 LL-----LVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYGFTEADLDREFFLGVWNMS 179
L+ ++ A++ G+ ++ +DPL LK+R +LD Y FTE + + + N +
Sbjct: 68 LIKKIDHMIHAFRSEGYQQSLIDPLKLKKRTKIHDLDLSFYNFTEEETRQTVEINFKNCT 127
Query: 180 GFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETP-SPTQFSRER 238
F + + S+ L + YCGSIG+EYM++ + + W+ + IE+ + F+ E
Sbjct: 128 NFRTN------IISLYKILYKKYCGSIGFEYMYVNNLLEKQWITNHIESFFNENVFTIEE 181
Query: 239 REVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVENIVMGMA 298
+ L ++ E ++ K+ AKRF LEG ETLIP + E+ + + IV+GMA
Sbjct: 182 KINFLKELTYAETLEKYIGKKFPGAKRFSLEGAETLIPVLHEVIRFSKKNNISKIVLGMA 241
Query: 299 HRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTG-TGDVKYHLGTSYDRPTRGGRRI 357
HRGRLNVL NV+ K + +F EFS + L+ +GDVKYH+G + + + ++I
Sbjct: 242 HRGRLNVLINVLNKSPKVLFDEFSN------LNLFQKISGDVKYHMGGTAE--IQYEKKI 293
Query: 358 HLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKN--MGVLIHGDGSFAGQGVVYETL 415
+ NPSHLE +NP+V G +R+ Y ++ + + N + + IHGD S GQGVV ETL
Sbjct: 294 IFHMACNPSHLEIINPVVSGISRS---YIDNMKNIDNEVLPISIHGDASVIGQGVVQETL 350
Query: 416 HLSALPNYTTGGTIHIVFNNQVAFTT-DPESGRSSQYSTDVAKALNAPIFHVNGDDVESV 474
++S Y GGT+HI+ NNQ+ FTT +P+ RSS+Y TDVAK + AP+FHVN DD+E+
Sbjct: 351 NMSQTEGYKVGGTVHIIINNQIGFTTSNPKHLRSSEYCTDVAKIIQAPVFHVNADDLEAS 410
Query: 475 VHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQKK 534
+ +LA +R+ F DV +DLVCYRR GHNE+DEPS TQP MY+ I+NHP++ IY
Sbjct: 411 IFAIQLALHFRKIFKKDVFIDLVCYRRNGHNEVDEPSVTQPIMYQKIKNHPTSRTIYSDV 470
Query: 535 LLELGELTQEDIDKIHKKVTSILND-EFLASKDYIPKRRDWLSAYWSGFKSPEQLSRIRN 593
L+ +T E +I + S L ++ SK K + + + F +++ +I+
Sbjct: 471 LISKKIITSEKNQEIMNQYLSKLQKGHYIFSKS---KNIHFKNEF---FLEEKKIKKIKK 524
Query: 594 TGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEALAFATLIV 653
V LKN+ I +P+S+ H+ VKK+YE+R +M + + DWG AE LA+AT++
Sbjct: 525 D-VNFSDLKNLACLINQIPDSVKMHQRVKKIYEERLEMAQRLKLFDWGAAETLAYATILN 583
Query: 654 EGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEMFTVSNSSLSEFGV 713
EG R+SG+DV RGTF HRHA +H+Q G Y PL+++ Q + F + +S LSE V
Sbjct: 584 EGISCRISGEDVSRGTFFHRHAFIHNQINGSIYIPLNNISKKQGK--FQIWDSVLSEEAV 641
Query: 714 LGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLVVLLPHGYDG 773
L FE GYS+ +PN+L IWEAQFGDF NGAQ++ D F+SSGE KW +++ LVVLLPHGY+G
Sbjct: 642 LAFEYGYSLSSPNTLTIWEAQFGDFINGAQIVIDQFISSGEQKWNKKSNLVVLLPHGYEG 701
Query: 774 QGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTTPANFFHVLRRQIH 833
QGPEHSS R+ER+LQ+ E N+QI TT + FH+ R+QI
Sbjct: 702 QGPEHSSSRIERFLQLC------------------AEENMQICIPTTSSQIFHIFRKQIF 743
Query: 834 REFRKPLIVMSPKNLLRSKVCRSNLSEFDD-VQGHPGFDKQGTRFKRLIKDQNDHSNVEE 892
+ KPLI+ +PK+LLR+ + S+ FDD V G +F++++ D+ D+ N +E
Sbjct: 744 DKILKPLIIFTPKSLLRNPMASSS---FDDLVYG---------KFQKIL-DEVDNVNKKE 790
Query: 893 GIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRELKRY-PNAEVVWC 951
RLI CSGK+YY+L R + + + R+EQL PFP + + LK Y + +WC
Sbjct: 791 --IRLIFCSGKIYYDLLRNRREKKINSIILIRIEQLYPFPEGEILKILKNYFYIKDFIWC 848
Query: 952 QEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKVHQREQAELVH 1011
QEEP N G + YI L + +KY+GR+ SA+ A G++ +H+++Q ++++
Sbjct: 849 QEEPYNQGAWFYIKDCLSNILPL-----DASLKYIGRSSSASPAVGYISIHKKQQEKIIY 903
Query: 1012 KAM 1014
A+
Sbjct: 904 NAL 906
>ODO1_BUCBP (Q89AJ7) Oxoglutarate dehydrogenase (EC 1.2.4.2)
Length = 916
Score = 621 bits (1602), Expect = e-177
Identities = 359/966 (37%), Positives = 554/966 (57%), Gaps = 71/966 (7%)
Query: 63 SRLTDNFLDGTSSAYLEELQRAWEADPSSVDESWDNFF-----RNFVGQASTSPGISGQT 117
+ +++ +S+Y++ L + DP+S+D SW F N++ + Q
Sbjct: 4 NEFNSSWMSSFNSSYIDNLYNKFLLDPTSIDNSWYIVFTELSKENYINSTNKYLNNKFQD 63
Query: 118 IQESMRLL--LLVRAYQVNGHMKAKLDPLGLKERNIPDELDPGLYGFTEADLDREFFLGV 175
+++++L LL+ ++ G+ A L+PL + + L L + + +
Sbjct: 64 SKDTIKLTIELLINIFRTLGYKFAHLNPLDTFKNDNSLSLKKFLKSSEAFRIQDSYLV-- 121
Query: 176 WNMSGFLSENRPVQTLRSILTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPTQFS 235
+S ++ ++ T +++ + YC IGY++MHI + ++ NW+++ IET
Sbjct: 122 -KLSQYVLDDI---TTKNVYDDYKNIYCKRIGYQFMHIHNSNEMNWIKNYIETKHSNILK 177
Query: 236 RERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVENIVM 295
++++ I L S + E + ++K+ S KRF +EG E+LIP +KE+ + I+
Sbjct: 178 KKKKIQILKHLIISEMLEKYFSSKFPSIKRFSIEGAESLIPMLKEVIKYTKKFNLHKIIF 237
Query: 296 GMAHRGRLNVLGNVVRKPLRQIFCEFSGGLPQDEVGLYTGTGDVKYHLGTSYDRPTRGGR 355
GM+HRGRLNVL N++ KP++ IF EF + +GDVKYH+G + T G R
Sbjct: 238 GMSHRGRLNVLANILDKPIKTIFNEFCENNSNN-----FNSGDVKYHMGFCCTK-TIGLR 291
Query: 356 RIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDAERMKN-MGVLIHGDGSFAGQGVVYET 414
+I L L +NPSHLE +NP+VVG +RA SND +N + ++IHGD + +GQGVV E
Sbjct: 292 KIILDLKSNPSHLEVINPVVVGSSRA-YIDSNDNLNDENILPIIIHGDAAISGQGVVQEL 350
Query: 415 LHLSALPNYTTGGTIHIVFNNQVAFTTDPESG-RSSQYSTDVAKALNAPIFHVNGDDVES 473
L++S Y GGTIHIV NNQ+ FTT R+SQY TD+AK +++PIFHVN DD ES
Sbjct: 351 LNMSQARGYKVGGTIHIVVNNQIGFTTSKVKDLRTSQYCTDIAKMIDSPIFHVNADDPES 410
Query: 474 VVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQK 533
V+ V LA +R F DV ++LVCYRR GHNEID+PS TQP +Y I+NHP+ Y
Sbjct: 411 VIFVTHLALNYRFCFKKDVFINLVCYRRHGHNEIDDPSITQPVLYSKIKNHPTTATSYYN 470
Query: 534 KLLELGELTQEDIDKIHKKVTSILNDEF-LASKDYIPKRRDWLSAYWSGFKSPEQLSRIR 592
KLL + + + KK+ L+ E+ L +K KR S + + + +S
Sbjct: 471 KLLLKNIINKSFLITYQKKIKKKLDVEYNLHNKKMSEKRLKCCSIVKADYIN---VSNTP 527
Query: 593 NTGVKPDILKNVGKAITALPESLNPHRAVKKVYEQRAQMVETGEDIDWGFAEALAFATLI 652
+ L + K I ++P ++ H V K+Y+ R +M + DWG +E LA+A+L+
Sbjct: 528 INNISQSDLTILAKKIFSIPNNIEVHNRVFKIYKDRLKMANNEKLFDWGASELLAYASLL 587
Query: 653 VEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEEMFTVSNSSLSEFG 712
EG RLSG+DV RGTF HRHAV+HDQ KY PL ++ + Q F + +S LSE
Sbjct: 588 NEGISCRLSGEDVCRGTFFHRHAVIHDQKNDSKYIPLKNIKLKQGN--FYIWDSVLSEEA 645
Query: 713 VLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLRQTGLVVLLPHGYD 772
L FE GYS++ N+L +WEAQFGDFANGAQ+I D F+ SGE KW LV+LLPHGY+
Sbjct: 646 TLAFEYGYSIDQKNTLNVWEAQFGDFANGAQIIIDQFICSGEQKWNVTCNLVMLLPHGYE 705
Query: 773 GQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVTTPANFFHVLRRQI 832
GQGPEHSS R+ERYLQ++ ++ N++I+ T + +H++R+Q
Sbjct: 706 GQGPEHSSARIERYLQLSANN------------------NIKIIIPTISSQIYHIIRKQA 747
Query: 833 HREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSNVEE 892
+KPLI+MSPK+LLR + S+LSE + +F+ +I D+ D+ + ++
Sbjct: 748 FSLIKKPLIIMSPKSLLRFPLAASSLSELSN-----------GKFRTVI-DEIDNLDTKK 795
Query: 893 GIRRLILCSGKVYYELDEQRTKDDAKDVAICRVEQLCPFPYDLVQRELKRYPNA-EVVWC 951
++R+ILCSGK+YY+L QR + K++ I R+EQ+ P P + L Y + + +WC
Sbjct: 796 -VQRIILCSGKIYYDLLTQRRINQQKNIVILRIEQIYPRPTKKLSAILYNYKDVHDYIWC 854
Query: 952 QEEPMNMGGYSY---ILPRLITSMKALGRGGYEDVKYVGRAPSAATATGFLKVHQREQAE 1008
QEEP N G + Y L +L+ + + YVGR+ SA+ ATG++K+H+ +Q +
Sbjct: 855 QEEPCNQGAWLYHKSYLKKLLPK--------HSKLNYVGRSSSASPATGYMKIHKEQQKK 906
Query: 1009 LVHKAM 1014
+++ A+
Sbjct: 907 IIYDAL 912
>ODO1_BACSU (P23129) 2-oxoglutarate dehydrogenase E1 component (EC
1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Length = 941
Score = 553 bits (1426), Expect = e-157
Identities = 356/984 (36%), Positives = 537/984 (54%), Gaps = 98/984 (9%)
Query: 72 GTSSAYLEELQRAWEADPSSVDESWDNFFRNFVGQASTSPGISG------------QTIQ 119
G + Y EL + DP S+D F S SG Q I
Sbjct: 17 GPNLGYALELYDQYTQDPYSIDPDLKEMFDELGAPPSDIKEASGTKEKGRVTADLIQKIA 76
Query: 120 ESMRLLLLVRAYQVNGHMKAKLDPLGLKERNIPDELDP-GLYGFTEADLDREFFLGVWNM 178
++RL +R Y GH+ A ++PL E+ EL P YG TE ++
Sbjct: 77 SAVRLAEDIRTY---GHLNASVNPLRKDEKK--SELFPLSDYGLTEEEIKAI-------P 124
Query: 179 SGFLSENRPVQTLRSI--LTRLEQAYCGSIGYEYMHIPDRDKCNWLRDKIETPSPTQF-S 235
+ + ++ P + + L Y +I +E+ H+ D + WL KIE+ Q S
Sbjct: 125 ASVICKDAPKNISNGLEAIQYLRNTYKRTISFEFDHVHDFKEREWLTRKIESGELFQKNS 184
Query: 236 RERREVIFDRLAWSTLFENFLATKWTSAKRFGLEGGETLIPGMKEMFDRASDLGVENIVM 295
E+ + +RL FE FL + KRF +EG + L+P + ++ ++ G ++ +
Sbjct: 185 AEKLSAVLERLTEVEGFEQFLHRTFVGQKRFSIEGLDALVPVLDDIIAQSVKSGTTSVNI 244
Query: 296 GMAHRGRLNVLGNVVRKPLRQIFCEFSGG---LPQDEVGLYTGTGDVKYHLGTSYDR--- 349
GMAHRGRLNVL +V+ KP IF EF L E L + T D + T + R
Sbjct: 245 GMAHRGRLNVLAHVLGKPYEIIFSEFQHAPRSLVPSEDPLESAT-DGRGMSNTIWGRIGS 303
Query: 350 -PTRGGRRIHLSLMANPSHLEAVNPLVVGKTRAKQYYSNDA-----ERMKNMGVLIHGDG 403
T + L L NPSHLE +NP+V G TRA Q + + K++ +LIHGD
Sbjct: 304 FKTLKQNQPALPLANNPSHLEFINPIVEGSTRAAQETRTQSGYPVQDETKSLAILIHGDA 363
Query: 404 SFAGQGVVYETLHLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPI 463
+F G+G+V ETL+LS+L Y GG IHI+ NN + FTT+ RS++Y++D+AK PI
Sbjct: 364 AFPGEGIVAETLNLSSLKGYQVGGAIHIIANNMIGFTTESAESRSTKYASDLAKGYEIPI 423
Query: 464 FHVNGDDVESVVHVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRN 523
HVN DD E+ + + A E+R+TF+ D ++DL+ YRR+GHNE+DEPS TQP +Y +R
Sbjct: 424 VHVNADDPEACLSAVKFAVEYRKTFNKDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRK 483
Query: 524 HPSALEIYQKKLLELGELTQEDIDKIHKKVTSILNDEFLASKDYIPKRRDWLSAYWSGFK 583
HP++ + KKL++ G +T+E + I K VT + + +P +++ + +
Sbjct: 484 HPTSNKFSLKKLVKEGVVTEEVVQNIEKSVTKRIE----VAIQKVPSKKEHTAC---EIE 536
Query: 584 SPEQLSR---IRNTGVKPDILKNV-GKAITALPESLNPHRAVKKVYEQRAQMVETGEDID 639
PE +S +T + +L+ + G+ IT ES +A K + + A+ + ++
Sbjct: 537 LPEPVSNGFPDVDTSIHFHVLRKLNGELITG--ESFMFSQA-KAHFRKTAKAFDDDRKVE 593
Query: 640 WGFAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVVHDQATGEKYCPLDHVIMNQNEE 699
W AE+LAFA+++ +G +RL+GQD ERGTF+ R+ V+HD TG+++ PL H ++
Sbjct: 594 WSLAESLAFASILKDGTPIRLTGQDSERGTFAQRNLVLHDSETGKEFVPLHH--LSDCST 651
Query: 700 MFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVIFDNFLSSGESKWLR 759
F V NS LSE VLGFE GY++ +P +LV+WEAQ+GDFAN AQV FD F+S+G +KW +
Sbjct: 652 SFAVHNSPLSEGSVLGFEYGYNVHSPETLVLWEAQYGDFANAAQVYFDQFISAGRAKWGQ 711
Query: 760 QTGLVVLLPHGYDGQGPEHSSGRLERYLQMADDHPYIIPEMDPTLRKQIQECNLQIVNVT 819
++GLV+LLPHGY+GQGPEHSSGR+ER+LQ+A E N + N+T
Sbjct: 712 KSGLVMLLPHGYEGQGPEHSSGRIERFLQLA------------------AENNWTVANLT 753
Query: 820 TPANFFHVLRRQ---IHREFRKPLIVMSPKNLLRSKVCRSNLSEFDDVQGHPGFDKQGTR 876
+ A +FH+LRRQ + RE +PL++M+PK+LLR+ S + E + + P +++ G
Sbjct: 754 SAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNTVSEVQELSESRFQPVYEQSGL- 812
Query: 877 FKRLIKDQNDHSNVEEGIRRLILCSGKVYYELDEQRTK-DDAKD-VAICRVEQLCPFPYD 934
S+ E + RL+L SGKV ++ K +D K+ + I R+EQL PFP
Sbjct: 813 -----------SHDYEKVTRLVLSSGKVSIDISVHFNKLEDGKEWLHIARIEQLYPFPAK 861
Query: 935 LVQRELKRYPN-AEVVWCQEEPMNMGGYSYILPRLITSMKALGRGGYEDVKYVGRAPSAA 993
V+ + PN E+VW QEEP NMG + YI P L T + G V+Y+GR ++
Sbjct: 862 GVKELFAKLPNLKEIVWVQEEPQNMGAWGYISPYL-TEIAPEG----VSVQYIGRRRRSS 916
Query: 994 TATGFLKVHQREQAELVHKAMQHK 1017
A G VH++EQ +V ++ K
Sbjct: 917 PAEGDPTVHKKEQERIVSDSLTRK 940
>ODPA_RHIME (Q9R9N5) Pyruvate dehydrogenase E1 component, alpha
subunit (EC 1.2.4.1)
Length = 348
Score = 67.0 bits (162), Expect = 2e-10
Identities = 48/186 (25%), Positives = 89/186 (47%), Gaps = 9/186 (4%)
Query: 374 LVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVF 433
L G A +Y ND N+ + GDG+ A QG VYE+ +++AL I+IV
Sbjct: 150 LGTGLAFANRYRGND-----NVSLAYFGDGA-ANQGQVYESFNMAALWKLPV---IYIVE 200
Query: 434 NNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTFHSDVV 493
NN+ A T + + + P + V+G DV +V + A E ++ ++
Sbjct: 201 NNRYAMGTSVSRASAQTDFSQRGASFGIPGYQVDGMDVRAVKAAADEAVEHCRSGKGPII 260
Query: 494 VDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQKKLLELGELTQEDIDKIHKKV 553
++++ YR GH+ D + + +R+ +E + +L + G T++++ +I K+V
Sbjct: 261 LEMLTYRYRGHSMSDPAKYRSKDEVQKMRSEHDPIEQVKARLTDKGWATEDELKQIDKEV 320
Query: 554 TSILND 559
I+ D
Sbjct: 321 RDIVAD 326
>ODPT_ASCSU (P26268) Pyruvate dehydrogenase E1 component alpha
subunit type II, mitochondrial precursor (EC 1.2.4.1)
(PDHE1-A) (Fragment)
Length = 391
Score = 56.2 bits (134), Expect = 4e-07
Identities = 53/242 (21%), Positives = 107/242 (43%), Gaps = 30/242 (12%)
Query: 313 PLRQIFCEFSGGLPQDEVGLYTGTGDVKYHLGTSYDRPTRGGRRIHLSLMANPSHLEAVN 372
P+ ++ CE +G + G G G + G ++ GG I + A
Sbjct: 121 PVAKVLCELTGRI----TGNVYGKGGSMHMYGENF----YGGNGI----------VGAQQ 162
Query: 373 PLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIV 432
PL G A +Y ++ KN+ + + GDG+ QG +YE+++++ L +++
Sbjct: 163 PLGTGIAFAMKY-----KKQKNVCITLFGDGA-TNQGQLYESMNMAKLWELPV---LYVC 213
Query: 433 FNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTFHSDV 492
NN T + RSS + + P F V+G DV +V EW +
Sbjct: 214 ENNGYGMGTS--AARSSASTDYYTRGDYVPGFWVDGMDVLAVRQAIRWGKEWCNAGKGPL 271
Query: 493 VVDLVCYRRFGHNEIDE-PSFTQPKMYKVIRNHPSALEIYQKKLLELGELTQEDIDKIHK 551
++++ YR GH+ D S+ + + +R + ++ K++ G +T++++ ++ K
Sbjct: 272 MIEMATYRYGGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDKIVTAGLVTEDELKEVDK 331
Query: 552 KV 553
++
Sbjct: 332 EI 333
>ODPA_KLULA (O13366) Pyruvate dehydrogenase E1 component alpha
subunit, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A)
Length = 412
Score = 53.5 bits (127), Expect = 3e-06
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 373 PLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIV 432
PL G A QY DA ++GDG+ + QG V+E+ +++ L N +
Sbjct: 184 PLGAGLAFAHQYKHEDA-----CSFALYGDGA-SNQGQVFESFNMAKLWNLPA---VFCC 234
Query: 433 FNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTFHSDV 492
NN+ T + RSS + + P VNG D+ +V + A +W + + +
Sbjct: 235 ENNKYGMGT--AAARSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWTVSGNGPI 292
Query: 493 VVDLVCYRRFGHNEIDEPSFTQPKMYKV--IRNHPSALEIYQKKLLELGELTQEDIDKIH 550
V++ YR GH+ + +P T ++ +R+ + + LLELG T+++I K +
Sbjct: 293 VLEYETYRYGGHS-MSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLLELGIATEDEI-KAY 350
Query: 551 KKVTSILNDEFLASKDYIPKRRDWLS-----AYWSGFKSPEQLSRIR 592
K DE + D P +S Y G ++P R++
Sbjct: 351 DKAARKYVDEQVELADAAPAPEAKMSILFEDVYVPGSETPTLRGRLQ 397
>ODPA_CAEEL (P52899) Probable pyruvate dehydrogenase E1 component
alpha subunit, mitochondrial precursor (EC 1.2.4.1)
(PDHE1-A)
Length = 397
Score = 53.1 bits (126), Expect = 4e-06
Identities = 56/247 (22%), Positives = 112/247 (44%), Gaps = 21/247 (8%)
Query: 370 AVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTI 429
A PL G A +Y KN+ V ++GDG+ A QG ++E +++ L + +
Sbjct: 163 AQQPLGAGVALAMKY-----REQKNVCVTLYGDGA-ANQGQLFEATNMAKLWDLPV---L 213
Query: 430 HIVFNNQVAF-TTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTF 488
+ NN TT S S++Y T + P V+G D+ +V + A E+ +
Sbjct: 214 FVCENNGFGMGTTAERSSASTEYYT---RGDYVPGIWVDGMDILAVREATKWAKEYCDSG 270
Query: 489 HSDVVVDLVCYRRFGHNEIDE-PSFTQPKMYKVIRNHPSALEIYQKKLLELGELTQEDID 547
+++++ YR GH+ D S+ + + +R + ++ +++ T+E++
Sbjct: 271 KGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELK 330
Query: 548 KIHKKVTSILND--EFLASKDYIPKRRDWLSAYWSGFKSPEQLSRIRNTGVKP-----DI 600
I K+V +++ + S +P + Y + + + I T V+P D+
Sbjct: 331 AIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQEIRGATIDETIVQPFKTSADV 390
Query: 601 LKNVGKA 607
LK++G+A
Sbjct: 391 LKSIGRA 397
>ODPA_MYCPN (P75390) Pyruvate dehydrogenase E1 component, alpha
subunit (EC 1.2.4.1)
Length = 358
Score = 52.0 bits (123), Expect = 8e-06
Identities = 44/198 (22%), Positives = 92/198 (46%), Gaps = 12/198 (6%)
Query: 364 NPSHLEA-VNPLVVGKTRAKQY-------YSNDAERMKNMGVLIHGDGSFAGQGVVYETL 415
N S +EA L + T QY Y +++ N+ V + GDG A +G YE +
Sbjct: 118 NGSKIEAKYKTLPINITIGAQYSHAAGLGYMLHYKKLPNVAVTMIGDGGTA-EGEFYEAM 176
Query: 416 HLSALPNYTTGGTIHIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVV 475
+++++ + + + + NNQ A +T + + + A A+N P V+G+D+ +
Sbjct: 177 NIASIHKWNS---VFCINNNQFAISTRTKLESAVSDLSTKAIAVNIPRIRVDGNDLIASY 233
Query: 476 HVCELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRNHPSALEIYQKKL 535
AA + ++ + V+++ +R+ H D+PS + K + ++ + L
Sbjct: 234 EAMHEAANYARSGNGPVLIEFFSWRQGPHTTSDDPSIYRTKEEEAEAMKSDPVKRLRNFL 293
Query: 536 LELGELTQEDIDKIHKKV 553
+ G LT + +++ K+
Sbjct: 294 FDRGILTPQQEEEMVAKI 311
>ODPA_ASCSU (P26267) Pyruvate dehydrogenase E1 component alpha
subunit type I, mitochondrial precursor (EC 1.2.4.1)
(PDHE1-A)
Length = 396
Score = 51.6 bits (122), Expect = 1e-05
Identities = 44/185 (23%), Positives = 87/185 (46%), Gaps = 12/185 (6%)
Query: 370 AVNPLVVGKTRAKQYYSNDAERMKNMGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTI 429
A PL G A +Y + KN+ + + GDG+ QG ++E+++++ L + +
Sbjct: 165 AQQPLGTGIAFAMKY-----RKEKNVCITMFGDGA-TNQGQLFESMNMAKLWDLPV---L 215
Query: 430 HIVFNNQVAFTTDPESGRSSQYSTDVAKALNAPIFHVNGDDVESVVHVCELAAEWRQTFH 489
++ NN T + RSS + + P V+G DV +V A EW
Sbjct: 216 YVCENNGYGMGT--AAARSSASTDYYTRGDYVPGIWVDGMDVLAVRQAVRWAKEWCNAGK 273
Query: 490 SDVVVDLVCYRRFGHNEIDE-PSFTQPKMYKVIRNHPSALEIYQKKLLELGELTQEDIDK 548
+++++ YR GH+ D S+ + + +R + ++ K++ G +T+++I +
Sbjct: 274 GPLMIEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDKIVTAGLVTEDEIKE 333
Query: 549 IHKKV 553
I K+V
Sbjct: 334 IDKQV 338
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129,265,721
Number of Sequences: 164201
Number of extensions: 5908481
Number of successful extensions: 13465
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 13278
Number of HSP's gapped (non-prelim): 51
length of query: 1023
length of database: 59,974,054
effective HSP length: 120
effective length of query: 903
effective length of database: 40,269,934
effective search space: 36363750402
effective search space used: 36363750402
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Lotus: description of TM0180a.12