BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0175.3
         (520 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PCNB_HAEIN (P44439) Probable poly(A) polymerase (EC 2.7.7.19) (PAP)   134  6e-31
PCNB_SALTY (Q8ZRQ8) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas...   134  7e-31
PCNB_SALTI (Q8Z9C3) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas...   134  7e-31
PCNB_ECOLI (P13685) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas...   133  1e-30
PAPS_BACSU (P42977) Poly(A) polymerase (EC 2.7.7.19) (PAP)             94  1e-18
CCA_HAEIN (P45269) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    64  7e-10
CCA1_SCHPO (Q9UTQ0) Probable tRNA nucleotidyltransferase (EC 2.7...    63  2e-09
CCA_ECOLI (P06961) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    62  3e-09
CCA1_MOUSE (Q8K1J6) tRNA-nucleotidyltransferase 1, mitochondrial...    61  6e-09
CCA1_HUMAN (Q96Q11) tRNA-nucleotidyltransferase 1, mitochondrial...    61  6e-09
CCA_BUCAI (P57169) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    59  4e-08
CCA_AERHY (P45749) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    58  5e-08
CCA_BUCAP (Q8KA53) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    57  1e-07
CCA1_YEAST (P21269) tRNA nucleotidyltransferase, mitochondrial p...    54  1e-06
CCA_BUCBP (Q89B06) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    53  2e-06
CCA1_CANGA (Q9P4S5) tRNA nucleotidyltransferase, mitochondrial p...    49  3e-05
CCA_FRANO (Q47907) tRNA nucleotidyltransferase (EC 2.7.7.25) (tR...    33  1.4
YDE3_SCHPO (Q10437) Hypothetical WD-repeat protein C12B10.03 in ...    32  4.0
RPOC_COREF (Q8FS96) DNA-directed RNA polymerase beta' chain (EC ...    32  4.0
HEPA_HHV2H (P89431) DNA helicase/primase complex associated protein    31  8.9

>PCNB_HAEIN (P44439) Probable poly(A) polymerase (EC 2.7.7.19) (PAP)
          Length = 452

 Score =  134 bits (337), Expect = 6e-31
 Identities = 75/239 (31%), Positives = 125/239 (51%), Gaps = 15/239 (6%)

Query: 81  VLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFS-WCEIVGKRFPIC 139
           V+  L+++G++ Y+VGGC+RDL+L + PKDFD+ T+A  +++   F   C +VG+RF + 
Sbjct: 39  VVEKLQRQGFEAYIVGGCIRDLLLGKKPKDFDVATNARPEQIQNIFQRQCRLVGRRFRLA 98

Query: 140 HVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKN--------CLNRDFT 191
           H+     ++EV++F  N    R       E      NE  L   N           RDFT
Sbjct: 99  HIMFGRDIIEVATFRANHSDARN------ENQAKQSNEGMLLRDNVYGTIEQDAARRDFT 152

Query: 192 INGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLGFSIS 251
           +N L ++P    + DY  G++D+   K+R +    T +QED  R+LR+IR  A+L   + 
Sbjct: 153 VNALYYNPQDNTLRDYFEGIKDLKAGKLRLIGDPVTRYQEDPVRMLRSIRFMAKLDMFLE 212

Query: 252 RETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYF 310
           + +   ++ L+  +  +   RL  E   +L  G    + RLL ++GL + L P  + YF
Sbjct: 213 KPSEQPIRELAPLLKNIPPARLFDESLKLLQAGQGVKTYRLLRQYGLFEQLFPALSAYF 271


>PCNB_SALTY (Q8ZRQ8) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid
           copy number protein)
          Length = 472

 Score =  134 bits (336), Expect = 7e-31
 Identities = 83/243 (34%), Positives = 125/243 (51%), Gaps = 3/243 (1%)

Query: 74  IAHPTKRVLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVG 133
           I+    +VL  L K GY+ YLVGG VRDL+L + PKDFD+ T+A   +V + F  C +VG
Sbjct: 51  ISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPDQVRKLFRNCRLVG 110

Query: 134 KRFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGC---DNEDFLRWKNCLNRDF 190
           +RF + HV     ++EV++F  +     +         NG    DN      ++   RDF
Sbjct: 111 RRFRLAHVMFGPEIIEVATFRGHHEGSESDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDF 170

Query: 191 TINGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLGFSI 250
           TIN L +      V DY+GGM+D+ +  +R +    T ++ED  R+LRA+R AA+L   I
Sbjct: 171 TINSLYYSVADFTVRDYVGGMQDLQEGVIRLIGNPETRYREDPVRMLRAVRFAAKLNMHI 230

Query: 251 SRETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYF 310
           S ETA  +  L+  +  +   RL  E   +L  G+   + + L  + L   L P    YF
Sbjct: 231 SPETAEPIPRLATLLNDIPPARLFEESLKLLQAGNGYETYQQLREYHLFQPLFPTITRYF 290

Query: 311 VHH 313
             +
Sbjct: 291 TEN 293


>PCNB_SALTI (Q8Z9C3) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid
           copy number protein)
          Length = 472

 Score =  134 bits (336), Expect = 7e-31
 Identities = 83/243 (34%), Positives = 125/243 (51%), Gaps = 3/243 (1%)

Query: 74  IAHPTKRVLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVG 133
           I+    +VL  L K GY+ YLVGG VRDL+L + PKDFD+ T+A   +V + F  C +VG
Sbjct: 51  ISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPDQVRKLFRNCRLVG 110

Query: 134 KRFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGC---DNEDFLRWKNCLNRDF 190
           +RF + HV     ++EV++F  +     +         NG    DN      ++   RDF
Sbjct: 111 RRFRLAHVMFGPEIIEVATFRGHNEGSESDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDF 170

Query: 191 TINGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLGFSI 250
           TIN L +      V DY+GGM+D+ +  +R +    T ++ED  R+LRA+R AA+L   I
Sbjct: 171 TINSLYYSVADFTVRDYVGGMQDLQEGVIRLIGNPETRYREDPVRMLRAVRFAAKLNMRI 230

Query: 251 SRETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYF 310
           S ETA  +  L+  +  +   RL  E   +L  G+   + + L  + L   L P    YF
Sbjct: 231 SPETAEPIPRLATLLNDIPPARLFEESLKLLQAGNGFETYQQLREYHLFQPLFPTITRYF 290

Query: 311 VHH 313
             +
Sbjct: 291 TEN 293


>PCNB_ECOLI (P13685) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid
           copy number protein)
          Length = 472

 Score =  133 bits (335), Expect = 1e-30
 Identities = 83/243 (34%), Positives = 126/243 (51%), Gaps = 3/243 (1%)

Query: 74  IAHPTKRVLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVG 133
           I+    +V+  L K GY+ +LVGG VRDL+L + PKDFD+ T+A  ++V + F  C +VG
Sbjct: 51  ISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLVG 110

Query: 134 KRFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGC---DNEDFLRWKNCLNRDF 190
           +RF + HV     ++EV++F  +     +         NG    DN      ++   RDF
Sbjct: 111 RRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDF 170

Query: 191 TINGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLGFSI 250
           TIN L +      V DY+GGM+D+    +R +    T ++ED  R+LRA+R AA+LG  I
Sbjct: 171 TINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAKLGMRI 230

Query: 251 SRETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYF 310
           S ETA  +  L+  +  +   RL  E   +L  G    + +LL  + L   L P    YF
Sbjct: 231 SPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYF 290

Query: 311 VHH 313
             +
Sbjct: 291 TEN 293


>PAPS_BACSU (P42977) Poly(A) polymerase (EC 2.7.7.19) (PAP)
          Length = 397

 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 71/225 (31%), Positives = 108/225 (47%), Gaps = 8/225 (3%)

Query: 81  VLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPICH 140
           VL  L + G+  Y VGG VRD  +K+T  D DI T A   +V R F     VGK      
Sbjct: 11  VLRILIEAGHQAYFVGGAVRDSYMKRTIGDVDIATDAAPDQVERLFQRTVDVGKEHGTII 70

Query: 141 VHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPY 200
           V  +    EV++F T       R   +++  +  + ED  R      RD TIN +     
Sbjct: 71  VLWEDETYEVTTFRTESDYVDFRRPSEVQFISSLE-EDLKR------RDLTINAMAMTAD 123

Query: 201 AKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLGFSISRETAHSVKN 260
            K++ DY GG +DI +  +RTV      FQED  R+LRA+R  ++LGF++S ET  ++  
Sbjct: 124 GKVL-DYFGGKKDIDQKVIRTVGKPEDRFQEDALRMLRAVRFMSQLGFTLSPETEEAIAK 182

Query: 261 LSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPF 305
               +  +   R  +E   +L   ++  +L+ L +  L + L  F
Sbjct: 183 EKSLLSHVSVERKTIEFEKLLQGRASRQALQTLIQTRLYEELPGF 227


>CCA_HAEIN (P45269) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme)
          Length = 416

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 65/216 (30%), Positives = 94/216 (43%), Gaps = 17/216 (7%)

Query: 92  VYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPICHVHMDGTVVEVS 151
           VYLVGG VRD +L    KD D +        + S  + + VGK FP+           ++
Sbjct: 3   VYLVGGAVRDQLLGLPVKDRDWIVVGADPATLLSLGY-QQVGKDFPVFLNPKTKEEYALA 61

Query: 152 SFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVYDYMGGM 211
                     T F+ D  +P     +D +R      RD TIN +      +I+  Y GG 
Sbjct: 62  RTERKSSAGYTGFICDF-SPTITLEQDLIR------RDLTINAMAQSEDGEIIDPY-GGK 113

Query: 212 EDIVKAKVRTVVPAATSFQEDCARILRAIRIAAR---LGFSISRETAHSVKNLSYS--IL 266
           +D+    +R + PA   F ED  R+LR  R AAR   LGF I+ ET   +  L+ S  + 
Sbjct: 114 QDLENRILRHISPA---FSEDPLRVLRVARFAARYHSLGFKIASETLALMAELAQSGELQ 170

Query: 267 RLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDIL 302
            L   R+ +E    L   + E     L + G L +L
Sbjct: 171 HLTAERIWLETEKALNEKNPEIYFETLHKTGALSVL 206


>CCA1_SCHPO (Q9UTQ0) Probable tRNA nucleotidyltransferase (EC
           2.7.7.25) (tRNA adenylyltransferase) (tRNA
           CCA-pyrophosphorylase) (CCA-adding enzyme)
          Length = 534

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 58/234 (24%), Positives = 109/234 (45%), Gaps = 20/234 (8%)

Query: 82  LSTLKKKGYDVYLVGGCVRDLILKQTPKDFDI----LTSADLKEVMRSF------SWCEI 131
           +  + +K  +V   GG VRD +L+    D D+    ++  +  + ++S+       W   
Sbjct: 62  IGQMDRKEPEVRFAGGWVRDKLLRIESHDIDVAIDCMSGFEFAQHLQSYLAQQHPDWETK 121

Query: 132 VGK--RFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGCDNEDF-LRWKNCLNR 188
           V K    P+   H++     +   + +    R    HD    N  +   F    ++ L R
Sbjct: 122 VIKIDANPLKSKHLETATARIMGMDIDIVNLRH---HDYTNSNSSNKLVFGTPLEDALRR 178

Query: 189 DFTINGLMFDPYAKIVYDYMG-GMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARLG 247
           D TIN L ++  +K V D+ G G+ D+    +RT + A  +F +D  R +R IR A +  
Sbjct: 179 DATINALFYNLKSKTVEDFTGKGLVDLSNKIIRTPLVADETFGDDPLRAVRCIRFATKYD 238

Query: 248 FSISRETAHSVKNLS-YSILR--LDKGRLMMEMNYMLAYGSAEASLRLLWRFGL 298
           F+I  ET   +KN   +  LR  + + R+ +E++ ML + +   +L+++   G+
Sbjct: 239 FNIHEETIKGLKNPELHERLRSSISRERIGVEVDKMLKHCNTNRALKIIHSLGM 292


>CCA_ECOLI (P06961) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme)
          Length = 412

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 63/221 (28%), Positives = 99/221 (44%), Gaps = 23/221 (10%)

Query: 92  VYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPIC---HVHMDGTVV 148
           +YLVGG VRD +L    KD D +      + M    + + VG+ FP+      H +  + 
Sbjct: 3   IYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGY-QQVGRDFPVFLHPQTHEEYALA 61

Query: 149 EVSSFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVYDYM 208
                + + +   T +     AP+    +D  R      RD TIN L  D   +I+  Y 
Sbjct: 62  RTERKSGSGYTGFTCYA----APDVTLEDDLKR------RDLTINALAQDDNGEIIDPY- 110

Query: 209 GGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAAR---LGFSISRETAHSVKNLSYS- 264
            G+ D+    +R V PA   F ED  R+LR  R AAR   LGF I+ ET   ++ ++++ 
Sbjct: 111 NGLGDLQNRLLRHVSPA---FGEDPLRVLRVARFAARYAHLGFRIADETLALMREMTHAG 167

Query: 265 -ILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLP 304
            +  L   R+  E    L   + +   ++L   G L +L P
Sbjct: 168 ELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFP 208


>CCA1_MOUSE (Q8K1J6) tRNA-nucleotidyltransferase 1, mitochondrial
           precursor (EC 2.7.7.25) (mitochondrial tRNA nucleotidyl
           transferase, CCA-adding) (mt tRNA adenylyltransferase)
           (mt tRNA CCA-pyrophosphorylase) (mt tRNA
           CCA-diphosphorylase) (mt CCA-adding e
          Length = 434

 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 60/242 (24%), Positives = 98/242 (39%), Gaps = 13/242 (5%)

Query: 61  KLNSKELGLRNSMIAHPTKRVLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLK 120
           KL S E     S+     K +     K+ +++ + GG VRDL+    P+D D  T+A   
Sbjct: 31  KLQSPEF---QSLFTEGLKSLTELFAKENHELRIAGGAVRDLLNGVKPQDVDFATTATPT 87

Query: 121 EVMRSFSWCEIVGKRFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGCDNEDFL 180
           ++   F   +  G R         GT+   +  +   F+  T  +         + E   
Sbjct: 88  QMKEMF---QSAGIRMINNKGEKHGTIT--ARLHEENFEVTTLRIDVTTDGRHAEVEFTT 142

Query: 181 RW-KNCLNRDFTINGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRA 239
            W K+   RD TIN  MF  +   ++DY  G  D+   KVR V  A    QED  RILR 
Sbjct: 143 DWQKDAERRDLTINS-MFLGFDGTLFDYFNGYADLKNKKVRFVGHAKQRIQEDYLRILRY 201

Query: 240 IRIAARL---GFSISRETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRF 296
            R   R+         ET  ++   +  +  +   R+ +E+  +L        + L++  
Sbjct: 202 FRFYGRIVDRPGDHDHETLEAIAENAKGLAGISGERIWVELKKILTGDHVNHLIHLIYDL 261

Query: 297 GL 298
           G+
Sbjct: 262 GV 263


>CCA1_HUMAN (Q96Q11) tRNA-nucleotidyltransferase 1, mitochondrial
           precursor (EC 2.7.7.25) (Mitochondrial tRNA nucleotidyl
           transferase, CCA-adding) (mt tRNA adenylyltransferase)
           (mt tRNA CCA-pyrophosphorylase) (mt tRNA
           CCA-diphosphorylase) (mt CCA-adding e
          Length = 434

 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 54/187 (28%), Positives = 79/187 (41%), Gaps = 10/187 (5%)

Query: 61  KLNSKELGLRNSMIAHPTKRVLSTLKKKGYDVYLVGGCVRDLILKQTPKDFDILTSADLK 120
           KL S E     S+     K +     K+ +++ + GG VRDL+    P+D D  T+A   
Sbjct: 31  KLQSPEF---QSLFTEGLKSLTELFVKENHELRIAGGAVRDLLNGVKPQDIDFATTATPT 87

Query: 121 EVMRSFSWCEIVGKRFPICHVHMDGTVVEVSSFNTNKFKPRTRFVHDIEAPNGCDNEDFL 180
           ++   F   +  G R         GT+   +  +   F+  T  +         + E   
Sbjct: 88  QMKEMF---QSAGIRMINNRGEKHGTIT--ARLHEENFEITTLRIDVTTDGRHAEVEFTT 142

Query: 181 RW-KNCLNRDFTINGLMFDPYAKIVYDYMGGMEDIVKAKVRTVVPAATSFQEDCARILRA 239
            W K+   RD TIN  MF  +   ++DY  G ED+   KVR V  A    QED  RILR 
Sbjct: 143 DWQKDAERRDLTINS-MFLGFDGTLFDYFNGYEDLKNKKVRFVGHAKQRIQEDYLRILRY 201

Query: 240 IRIAARL 246
            R   R+
Sbjct: 202 FRFYGRI 208


>CCA_BUCAI (P57169) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme)
          Length = 414

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 66/234 (28%), Positives = 99/234 (42%), Gaps = 31/234 (13%)

Query: 92  VYLVGGCVRDLILKQTPKDFDILTSADLKEVM--RSFSWCEIVGKRFPICHVHMDGTVVE 149
           +YLVGG VRD +L    KD D +     ++++  R+F   + VGK FP+           
Sbjct: 3   IYLVGGAVRDSLLNLPVKDKDWVVVGGTEKILLERNF---QQVGKDFPVFLHPETHEEYA 59

Query: 150 VSSFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVYDYMG 209
           ++       K  T F  D        N D    ++ + RD TIN +  D Y   + D   
Sbjct: 60  LARKERKSGKGYTGFDTDC-------NSDVTLEEDLIRRDLTINAIAQDEYGNYI-DPFQ 111

Query: 210 GMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAA---RLGFSISRETAHSV------KN 260
           G +DI    +R V   + SF ED  R+LR  R AA    LGF I+ ET   +      + 
Sbjct: 112 GKKDIECGLIRHV---SESFIEDPLRVLRVARFAATLVHLGFKIAEETMLLMCIIVKKQE 168

Query: 261 LSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYFVHHR 314
           LSY    L   R+  E    L   +     ++L+    L    P   +YF++ +
Sbjct: 169 LSY----LTSNRIWNETEKALKTLNPHVYFQVLYECNALHFFFP--EMYFLYEK 216


>CCA_AERHY (P45749) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme) (Fragment)
          Length = 192

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 58/175 (33%), Positives = 86/175 (49%), Gaps = 19/175 (10%)

Query: 93  YLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPICHVHMDGTVVEVSS 152
           YLVGG VRD +L     D D L      E M +  + + VG+ FP+  +H   T  E + 
Sbjct: 4   YLVGGAVRDRLLGLPQGDRDHLVVGATVEQMLALGFTQ-VGRDFPV-FLH-PKTQQEYAL 60

Query: 153 FNTNKFKPR--TRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVYDYMGG 210
             T + + R  T FV    +P     +D LR      RD T+N +  D   ++ +D  GG
Sbjct: 61  ARTERKQGRGYTGFVCH-ASPEVTLEQDLLR------RDLTVNAIAEDEEGRL-HDPYGG 112

Query: 211 MEDIVKAKVRTVVPAATSFQEDCARILRAIRIAARL---GFSISRETAHSVKNLS 262
           ++D+ +  +R V PA   F ED  RILR  R AAR    GF ++ ET   ++ ++
Sbjct: 113 IQDLERRVLRHVSPA---FAEDPLRILRVARFAARFHAQGFVVAPETLALMREMT 164


>CCA_BUCAP (Q8KA53) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme)
          Length = 412

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 67/234 (28%), Positives = 102/234 (42%), Gaps = 31/234 (13%)

Query: 92  VYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPICHVHMDGTVVEVS 151
           VYLVGG VRD +L    KD D +     KE++   ++ + VGK FP+  +H + T  E S
Sbjct: 3   VYLVGGAVRDSLLNLPIKDRDWVIVGGTKEILLKKNF-QQVGKDFPV-FLHPE-THEEYS 59

Query: 152 SFNTNKFKPR------TRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVY 205
                +   R      T F  D+        ED +R      RD TIN +  D     + 
Sbjct: 60  LARKERKSGRGYTGFHTEFSSDVTL-----EEDLIR------RDLTINAIAQDENGNYI- 107

Query: 206 DYMGGMEDIVKAKVRTVVPAATSFQEDCARILRAIRIAA---RLGFSISRETAHSVKNL- 261
           D   G +D+    +R +   + SF ED  RILR  R AA    LGF I ++T   +  + 
Sbjct: 108 DPFQGRKDL---NLRLLRHVSESFTEDPLRILRTARFAANLMHLGFHIDKDTMILMCKMV 164

Query: 262 -SYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLPFQAVYFVHHR 314
               +L L K R+  E        +     ++L     L+ + P   ++F++ R
Sbjct: 165 KKNELLYLTKNRIWNETEKAFKTLNPHVYFQILHACKALNFIFP--EIFFLYER 216


>CCA1_YEAST (P21269) tRNA nucleotidyltransferase, mitochondrial
           precursor (EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA
           CCA-pyrophosphorylase) (CCA-adding enzyme)
          Length = 546

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 4/124 (3%)

Query: 183 KNCLNRDFTINGLMFDPYAKIVYDYMG-GMEDIVKAKVRTVVPAATSFQEDCARILRAIR 241
           ++ L RD T+N L ++ +   V D+   G++D+    +RT +PA  +F +D  R+LR IR
Sbjct: 167 EDALRRDATLNALFYNIHKGEVEDFTKRGLQDLKDGVLRTPLPAKQTFLDDPLRVLRLIR 226

Query: 242 IAARLGFSISRETAHSVKNLSYSIL---RLDKGRLMMEMNYMLAYGSAEASLRLLWRFGL 298
            A+R  F+I  E    + +   ++    ++ + R+ +EM  +L   +   +L+L+ R  L
Sbjct: 227 FASRFNFTIDPEVMAEMGDPQINVAFNSKISRERVGVEMEKILVGPTPLLALQLIQRAHL 286

Query: 299 LDIL 302
            +++
Sbjct: 287 ENVI 290


>CCA_BUCBP (Q89B06) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme)
          Length = 419

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 62/238 (26%), Positives = 99/238 (41%), Gaps = 26/238 (10%)

Query: 92  VYLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPICHVHMDGTVVEVS 151
           VYLVGG +R+  L    +D D +      E++ S  + + VGK FP+           ++
Sbjct: 3   VYLVGGAIRNKFLNLPVQDRDWVVVGATPEILLSLKFKQ-VGKGFPVFLHPYSKEEYSLA 61

Query: 152 SFNTNKFKPRTRFVHDIEAPNGCDNEDFLRWKNCLNRDFTINGLMFDPYAKIVYDYMGGM 211
             +       T F  D        N+  L+ ++ + RD TIN +  D     + D   G+
Sbjct: 62  RVDRKIGVGHTGFSFDY------SNKVTLK-EDLMRRDLTINAIAQDNNGNYI-DPFKGI 113

Query: 212 EDIVKAKVRTVVPAATSFQEDCARILRAIRIAA---RLGFSISRETAH--SVKNLSYSIL 266
            DI    +R V PA   F ED  R+LR  R  A    LGF I+ ET    S+   +  +L
Sbjct: 114 RDIKNRILRHVSPA---FSEDPLRVLRIARFCALFHHLGFRIATETMKIMSIVVKNNELL 170

Query: 267 RLDKGRLMMEMNYMLAYGSAEASLRLLWRFGLLDILLP-----FQAVYF----VHHRF 315
            L + R+  E        +     ++L     L ++ P     +Q  Y+    ++H F
Sbjct: 171 NLTRDRVWKETEKAFNTDNPHVYFQVLKNCNALSVIFPEINLVYQRQYYCIDNMYHNF 228


>CCA1_CANGA (Q9P4S5) tRNA nucleotidyltransferase, mitochondrial
           precursor (EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA
           CCA-pyrophosphorylase) (CCA-adding enzyme)
          Length = 531

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 34/124 (27%), Positives = 63/124 (50%), Gaps = 4/124 (3%)

Query: 183 KNCLNRDFTINGLMFDPYAKIVYDYMG-GMEDIVKAKVRTVVPAATSFQEDCARILRAIR 241
           ++ L RD T+N L ++     V D+   G +D+    +RT +PA  +F +D  R+LR IR
Sbjct: 151 EDALRRDATLNALFYNIQQDAVEDFTKRGWQDLQDGVLRTPLPARQTFLDDPLRVLRLIR 210

Query: 242 IAARLGFSISR---ETAHSVKNLSYSILRLDKGRLMMEMNYMLAYGSAEASLRLLWRFGL 298
            A+R  F+I     +  H  +       ++ + R+ +EM  +L   +    L+L+ R  L
Sbjct: 211 FASRFNFNIEAGVLKEMHDPEINEAFNNKISRERIGVEMEKILVGPNPILGLKLIQRTHL 270

Query: 299 LDIL 302
            +++
Sbjct: 271 ENVI 274


>CCA_FRANO (Q47907) tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA
           adenylyltransferase) (tRNA CCA-pyrophosphorylase)
           (CCA-adding enzyme) (Fragment)
          Length = 84

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 1/46 (2%)

Query: 93  YLVGGCVRDLILKQTPKDFDILTSADLKEVMRSFSWCEIVGKRFPI 138
           YLVGG VRD++L  TPKD D +     ++ M +  + +I    FP+
Sbjct: 4   YLVGGAVRDMLLGITPKDKDWVVVGATEDEMLANGFIKIAA-NFPV 48


>YDE3_SCHPO (Q10437) Hypothetical WD-repeat protein C12B10.03 in
           chromosome I
          Length = 543

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 278 NYMLAYGSAEASLRLLWRFGLLDILLPFQAVYFVHHRFRRRDKRTNMLLSLFSNLDKLLA 337
           NY +A    +  L LLW F +  I  P  AVY+V+H        +   +S F ++  L  
Sbjct: 423 NYRIASVGLDRKL-LLWDFSVSAIHRPKSAVYYVNH----HSNNSKPAISDFDDVGDLTM 477

Query: 338 PNRPCHSSLWVGILALHKTLS 358
            +   +S+   G + +H TLS
Sbjct: 478 GSEIDNSNYVNGDITIHPTLS 498


>RPOC_COREF (Q8FS96) DNA-directed RNA polymerase beta' chain (EC
           2.7.7.6) (RNAP beta' subunit) (Transcriptase beta'
           chain) (RNA polymerase beta' subunit)
          Length = 1333

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 372 LAVHNGGNLLEAVDISRRINQPHDDRFPELLDPSDLEAEALADEILDLAESVKESLLQMT 431
           L ++ G N++ +VD   R +         LL+  D+EA+A   EI + AE ++E L ++ 
Sbjct: 127 LIIYFGANIITSVDEEARHSDQSTLEAEMLLEKKDVEADA-ESEIAERAEKLEEDLAELE 185

Query: 432 TRHMVSQAMADYPQAPHSDMVFI 454
                + A      A   +M  I
Sbjct: 186 AAGAKADARRKVQNAAEKEMQHI 208


>HEPA_HHV2H (P89431) DNA helicase/primase complex associated protein
          Length = 752

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 23  QCVRKVSQLKLNLNHTHHLASSFISVCFPQNKKTPAWKKL-NSKELGLRNSMIAHPTKRV 81
           QC    S        T   A  + ++ FP  +K  A+  L    E+GLR     HP +  
Sbjct: 190 QCASSASLAVTITTRTARFAREYTTLAFPPTRKEGAFADLVEVCEVGLRPR--GHPQRVT 247

Query: 82  LSTLKKKGYDVYLVGG 97
              L  +GYD ++  G
Sbjct: 248 ARVLLPRGYDYFVSAG 263


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.325    0.138    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,469,624
Number of Sequences: 164201
Number of extensions: 2381704
Number of successful extensions: 6991
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 6957
Number of HSP's gapped (non-prelim): 23
length of query: 520
length of database: 59,974,054
effective HSP length: 115
effective length of query: 405
effective length of database: 41,090,939
effective search space: 16641830295
effective search space used: 16641830295
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)