BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0166.9
(746 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
KLC_DROME (P46824) Kinesin light chain (KLC) 76 4e-13
KLC8_HUMAN (Q9NSK0) Kinesin-like protein 8 74 2e-12
KLC_CAEEL (P46822) Kinesin light chain (KLC) 73 3e-12
KLC8_MOUSE (Q9DBS5) Kinesin-like protein 8 71 9e-12
KLC1_RAT (P37285) Kinesin light chain 1 (KLC 1) 66 3e-10
KLC2_HUMAN (Q9H0B6) Kinesin light chain 2 (KLC 2) 66 4e-10
KLC1_MOUSE (O88447) Kinesin light chain 1 (KLC 1) 66 4e-10
KLC1_HUMAN (Q07866) Kinesin light chain 1 (KLC 1) 65 5e-10
KLC2_MOUSE (O88448) Kinesin light chain 2 (KLC 2) 65 9e-10
KLC_LOLPE (P46825) Kinesin light chain (KLC) 64 2e-09
KLC_STRPU (Q05090) Kinesin light chain (KLC) 63 2e-09
KA43_HUMAN (Q96AY4) TPR repeat containing protein KIAA1043 53 3e-06
NFM_HUMAN (P07197) Neurofilament triplet M protein (160 kDa neur... 51 1e-05
OGT1_RAT (P56558) UDP-N-acetylglucosamine--peptide N-acetylgluco... 48 8e-05
OGT1_HUMAN (O15294) UDP-N-acetylglucosamine--peptide N-acetylglu... 48 8e-05
OGT_CAEEL (O18158) UDP-N-acetylglucosamine--peptide N-acetylgluc... 48 1e-04
TTCJ_HUMAN (Q6DKK2) Tetratricopeptide repeat protein 19 (TPR rep... 47 1e-04
IF3X_DICDI (O15818) Putative eukaryotic translation initiation f... 46 4e-04
NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa neur... 44 0.002
TTCJ_MOUSE (Q8CC21) Tetratricopeptide repeat protein 19 (TPR rep... 42 0.005
>KLC_DROME (P46824) Kinesin light chain (KLC)
Length = 508
Score = 75.9 bits (185), Expect = 4e-13
Identities = 75/328 (22%), Positives = 136/328 (40%), Gaps = 37/328 (11%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y ++Y E
Sbjct: 187 RTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKE 246
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL++ GENHPAV + LA L+ + GK K+++ C AL I E + G
Sbjct: 247 AANLLNDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVL-G 305
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+ ++A L N++ + ++ + ++ K Q+AL IY G ++A + + Y
Sbjct: 306 KDHPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYL 365
Query: 589 MLGNYTESYNTLKNAITKLR-----AIGEKKSSFIGIALNQMGLACVQLYAFGEATELFE 643
G YTE+ K +T+ AI K +A + F+
Sbjct: 366 KQGRYTEAEILYKQVLTRAHEREFGAIDSKNKPIWQVAEER-------------EEHKFD 412
Query: 644 EAKSILEHEYGPYH-------PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLG 696
++ EYG +H P NL Y G + A + + + ++E
Sbjct: 413 NRENTPYGEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMRSKKEAYD 472
Query: 697 TANPDVDDEKRRLSELLKEAGRVRSRKV 724
A ++ +LS+LL + RS+ +
Sbjct: 473 LA------KQTKLSQLLTSNEKRRSKAI 494
Score = 55.1 bits (131), Expect = 7e-07
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 3/200 (1%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y E+
Sbjct: 189 LHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAA 248
Query: 598 NTLKNAIT-KLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPY 656
N L +A++ + + +GE + + LN + + + + +A L + A I E G
Sbjct: 249 NLLNDALSIRGKTLGENHPA-VAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKD 307
Query: 657 HPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEA 716
HP+ +NLA G+ DE + + + + E KLG +P+V K L+ +
Sbjct: 308 HPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQ 367
Query: 717 GRVRSRKVMSLENLLDANAR 736
GR +++ + L A+ R
Sbjct: 368 GRYTEAEILYKQVLTRAHER 387
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/293 (21%), Positives = 119/293 (40%), Gaps = 22/293 (7%)
Query: 241 PILLKQARDLI---SSGDNPQKALELALQAMNLLEKLGNGKPSLELVMCLHVTAAIYCNL 297
P L+ +L+ +S + A+ L QA+ LE+ +G ++ L++ A +Y +
Sbjct: 183 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLERT-SGHDHPDVATMLNILALVYRDQ 241
Query: 298 GQYNEAIPILERSIEI--PVIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFE 355
+Y EA +L ++ I +GE+ A L Y G+ +++ E
Sbjct: 242 NKYKEAANLLNDALSIRGKTLGENHPAVAATLNN---LAVLYGKRGKYKDAEPLCKRALE 298
Query: 356 VQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIH--KANSSAPSLEEAAD 413
++ +VLG+ P V + +A ++DE E+ Q ALDI+ K P++ + +
Sbjct: 299 IREKVLGKDHPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKN 358
Query: 414 RRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDEAVFA 473
L G L EA + + ++ E E ++D + +E F
Sbjct: 359 -NLAGCYLKQGRYTEAEILY-----KQVLTRAHEREFGAIDSKNKPIWQVAEEREEHKFD 412
Query: 474 YEKALTVFKTGKGE-----NHPAVGSVFVRLADLHNRTGKIKESKSYCDSALR 521
+ + G + P V + L L+ R G + +++ D A+R
Sbjct: 413 NRENTPYGEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMR 465
>KLC8_HUMAN (Q9NSK0) Kinesin-like protein 8
Length = 625
Score = 73.6 bits (179), Expect = 2e-12
Identities = 51/198 (25%), Positives = 93/198 (46%), Gaps = 6/198 (3%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ +G +E A+ L + + +VA++ + Y ++Y E
Sbjct: 218 RTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKE 277
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL++ ++ G +HPAV + LA L+ + GK KE++ C AL I E + G
Sbjct: 278 AAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVL-G 336
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYY 588
N ++A L N++ + ++ + E + Q+AL IY G + ++A + + Y
Sbjct: 337 TNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYL 396
Query: 589 MLGNYTESYNTLKNAITK 606
G Y E+ K +T+
Sbjct: 397 KQGKYAEAETLYKEILTR 414
Score = 60.8 bits (146), Expect = 1e-08
Identities = 38/134 (28%), Positives = 58/134 (42%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y G Y + K A+ L + + LN + L + EA L +
Sbjct: 225 IQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLND 284
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A SI E GP HP +NLA Y G+ EA + + + +RE+ LGT +PDV
Sbjct: 285 ALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAK 344
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 345 QLNNLALLCQNQGK 358
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/196 (22%), Positives = 77/196 (38%), Gaps = 5/196 (2%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHA-LAKFAGHMQLGDTYAMLGQLEN 345
LH Y G+Y A+P+ ++++E + H +A + L Y + +
Sbjct: 220 LHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILAL--VYRDQNKYKE 277
Query: 346 SIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSSA 405
+ + ++ LG P V T +A + ++ EAE LCQ AL+I +
Sbjct: 278 AAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGT 337
Query: 406 PSLEEAADRRLMGLILDTKGNHEAALEHL--VLASMAMVANGQEVEVASVDCSIGDTYLS 463
+ A + L+ +G +EA + LA VA ++ YL
Sbjct: 338 NHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLK 397
Query: 464 MSRYDEAVFAYEKALT 479
+Y EA Y++ LT
Sbjct: 398 QGKYAEAETLYKEILT 413
Score = 46.6 bits (109), Expect = 2e-04
Identities = 42/199 (21%), Positives = 84/199 (42%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQ-QSSIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y + E A+ L ++AL + G+ +A + + ++Y Y E+
Sbjct: 220 LHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAA 279
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
+ L +A++ + + LN + + + + EA L + A I E G H
Sbjct: 280 HLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNH 339
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ +NLA G+ + + + +++ E +LG NP+V K L+ + G
Sbjct: 340 PDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQG 399
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + E L A+ +
Sbjct: 400 KYAEAETLYKEILTRAHVQ 418
Score = 45.8 bits (107), Expect = 4e-04
Identities = 63/272 (23%), Positives = 111/272 (40%), Gaps = 19/272 (6%)
Query: 260 ALELALQAMNLLEKL-GNGKPSLELVMCLHVTAAIYCNLGQYNEAIPILERSIEIPVIGE 318
A+ L QA+ LE+ G G P ++ L++ A +Y + +Y EA +L ++ I
Sbjct: 236 AVPLCKQALEDLERTSGRGHP--DVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTL 293
Query: 319 SQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEA 378
H A A L Y G+ + + E++ +VLG P V + +A
Sbjct: 294 GPDHP-AVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALL 352
Query: 379 NVQALQFDEAERLCQMALDIHKANSSAPSLEEAADRRLMGLILDTKGNH-EAALEHLVLA 437
+++ ER Q AL I++ + A + + +G + EA + +
Sbjct: 353 CQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 412
Query: 438 SMAMVANGQEVEVASVDCSIGDTYL--------SMSRYDEAVFAYEKALTVFKTGKGENH 489
+ A V E SVD ++ S SR+ E Y + +K K +
Sbjct: 413 TRAHVQ-----EFGSVDDDHKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSS- 466
Query: 490 PAVGSVFVRLADLHNRTGKIKESKSYCDSALR 521
P V + L L+ R GK++ +++ + ALR
Sbjct: 467 PTVNTTLRNLGALYRRQGKLEAAETLEECALR 498
>KLC_CAEEL (P46822) Kinesin light chain (KLC)
Length = 540
Score = 72.8 bits (177), Expect = 3e-12
Identities = 59/235 (25%), Positives = 110/235 (46%), Gaps = 11/235 (4%)
Query: 377 EANVQALQFDEAERLCQMALDIHKANSSAPSLEEAADRRLMGLILD--TKGNHEAALE-- 432
E ++ A QF++ QMA A+++ A R L L++ ++G +E A+
Sbjct: 175 EEDMNASQFNQPTPANQMA-----ASANVGYEIPARLRTLHNLVIQYASQGRYEVAVPLC 229
Query: 433 HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAV 492
L + + +VA++ + Y ++Y EA +AL++ + GE+HPAV
Sbjct: 230 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNEALSIREKCLGESHPAV 289
Query: 493 GSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNEL 552
+ LA L + GK K+++ C AL I E + +P ++A L N++ + ++ +
Sbjct: 290 AATLNNLAVLFGKRGKFKDAEPLCKRALEIREKVLGDDHP-DVAKQLNNLALLCQNQGKY 348
Query: 553 EKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITK 606
E+ K ++AL IY G ++A + + Y G Y E+ K +T+
Sbjct: 349 EEVEKYYKRALEIYESKLGPDDPNVAKTKNNLSSAYLKQGKYKEAEELYKQILTR 403
Score = 57.8 bits (138), Expect = 1e-07
Identities = 71/331 (21%), Positives = 123/331 (36%), Gaps = 36/331 (10%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + G+Y A+P+ ++++E L K +GH L Y
Sbjct: 209 LHNLVIQYASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVY 258
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
+ + + + ++ + LGE+ P V T +A + +F +AE LC+ AL+
Sbjct: 259 RDQNKYKEAANLLNEALSIREKCLGESHPAVAATLNNLAVLFGKRGKFKDAEPLCKRALE 318
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAALEHL--VLASMAMVANGQEVEVASVDC 455
I + + A + L+ +G +E ++ L + VA
Sbjct: 319 IREKVLGDDHPDVAKQLNNLALLCQNQGKYEEVEKYYKRALEIYESKLGPDDPNVAKTKN 378
Query: 456 SIGDTYLSMSRYDEAVFAYEKALT-----VFKTGKGENHPAVGSVFVRLADLHNRTGKIK 510
++ YL +Y EA Y++ LT F GEN P R + H G
Sbjct: 379 NLSSAYLKQGKYKEAEELYKQILTRAHEREFGQISGENKPIWQIAEEREENKHKGEGATA 438
Query: 511 ESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYND-S 569
++ A + V+ + + L N+ A+Y + E A L AL
Sbjct: 439 NEQAGWAKAAK--------VDSPTVTTTLKNLGALYRRQGKYEAAETLEDVALRAKKQHE 490
Query: 570 PGQQSSIAGI-EAQMGVMYYMLGNYTESYNT 599
P + ++ GI E +M +G S T
Sbjct: 491 PLRSGAMGGIDEMSQSMMASTIGGSRNSMTT 521
Score = 54.7 bits (130), Expect = 9e-07
Identities = 48/200 (24%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y E+
Sbjct: 209 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAA 268
Query: 598 NTLKNAIT-KLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPY 656
N L A++ + + +GE + + LN + + + F +A L + A I E G
Sbjct: 269 NLLNEALSIREKCLGESHPA-VAATLNNLAVLFGKRGKFKDAEPLCKRALEIREKVLGDD 327
Query: 657 HPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEA 716
HP+ +NLA G+ +E + + + + E KLG +P+V K LS +
Sbjct: 328 HPDVAKQLNNLALLCQNQGKYEEVEKYYKRALEIYESKLGPDDPNVAKTKNNLSSAYLKQ 387
Query: 717 GRVRSRKVMSLENLLDANAR 736
G+ + + + + L A+ R
Sbjct: 388 GKYKEAEELYKQILTRAHER 407
>KLC8_MOUSE (Q9DBS5) Kinesin-like protein 8
Length = 619
Score = 71.2 bits (173), Expect = 9e-12
Identities = 50/197 (25%), Positives = 93/197 (46%), Gaps = 6/197 (3%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ +G +E A+ L + + +VA++ + Y ++Y E
Sbjct: 212 RTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKE 271
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL++ ++ G +HPAV + LA L+ + GK KE++ C AL I E + G
Sbjct: 272 AAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVL-G 330
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYY 588
+ ++A L N++ + ++ + E + Q+AL IY G + ++A + + Y
Sbjct: 331 TDHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYESQLGPDNPNVARTKNNLASCYL 390
Query: 589 MLGNYTESYNTLKNAIT 605
G Y+E+ K +T
Sbjct: 391 KQGKYSEAEALYKEILT 407
Score = 57.4 bits (137), Expect = 1e-07
Identities = 37/134 (27%), Positives = 57/134 (41%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y G Y + K A+ L + + LN + L + EA L +
Sbjct: 219 IQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLND 278
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A SI E G HP +NLA Y G+ EA + + + +RE+ LGT +PDV
Sbjct: 279 ALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAK 338
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 339 QLNNLALLCQNQGK 352
Score = 50.1 bits (118), Expect = 2e-05
Identities = 44/196 (22%), Positives = 77/196 (38%), Gaps = 5/196 (2%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHA-LAKFAGHMQLGDTYAMLGQLEN 345
LH Y G+Y A+P+ ++++E + H +A + L Y + +
Sbjct: 214 LHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILAL--VYRDQNKYKE 271
Query: 346 SIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSSA 405
+ + ++ LG P V T +A + ++ EAE LCQ AL+I +
Sbjct: 272 AAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGT 331
Query: 406 PSLEEAADRRLMGLILDTKGNHEAALEHL--VLASMAMVANGQEVEVASVDCSIGDTYLS 463
+ A + L+ +G +EA + LA VA ++ YL
Sbjct: 332 DHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYESQLGPDNPNVARTKNNLASCYLK 391
Query: 464 MSRYDEAVFAYEKALT 479
+Y EA Y++ LT
Sbjct: 392 QGKYSEAEALYKEILT 407
Score = 47.8 bits (112), Expect = 1e-04
Identities = 42/199 (21%), Positives = 85/199 (42%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQ-QSSIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y + E A+ L ++AL + G+ +A + + ++Y Y E+
Sbjct: 214 LHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAA 273
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
+ L +A++ + + + LN + + + + EA L + A I E G H
Sbjct: 274 HLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDH 333
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ +NLA G+ + + + +++ E +LG NP+V K L+ + G
Sbjct: 334 PDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYESQLGPDNPNVARTKNNLASCYLKQG 393
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + E L A+ +
Sbjct: 394 KYSEAEALYKEILTCAHVQ 412
Score = 37.0 bits (84), Expect = 0.19
Identities = 36/137 (26%), Positives = 63/137 (45%), Gaps = 8/137 (5%)
Query: 258 QKALELALQAMNLLEK-LGNGKPSLELVMCLHVTAAIYCNLGQYNEAIPILERSIEI--P 314
++A L A+++ E LG P++ L+ A +Y G+Y EA P+ +R++EI
Sbjct: 270 KEAAHLLNDALSIRESTLGRDHPAVAAT--LNNLAVLYGKRGKYKEAEPLCQRALEIREK 327
Query: 315 VIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRY 374
V+G + +AK ++ L G+ E Y + LG +P V T
Sbjct: 328 VLG-TDHPDVAKQLNNLAL--LCQNQGKYEAVERYYQRALAIYESQLGPDNPNVARTKNN 384
Query: 375 VAEANVQALQFDEAERL 391
+A ++ ++ EAE L
Sbjct: 385 LASCYLKQGKYSEAEAL 401
>KLC1_RAT (P37285) Kinesin light chain 1 (KLC 1)
Length = 556
Score = 66.2 bits (160), Expect = 3e-10
Identities = 74/327 (22%), Positives = 133/327 (40%), Gaps = 37/327 (11%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y ++Y +
Sbjct: 210 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKD 269
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL + + G +HPAV + LA L+ + GK KE++ C AL I E + G
Sbjct: 270 AANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL-G 328
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+ ++A L N++ + ++ + E+ Q+AL IY G ++A + + Y
Sbjct: 329 KDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYL 388
Query: 589 MLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSI 648
G + ++ K +T+ + G + E EE K
Sbjct: 389 KQGKFKQAETLYKEILTRAHE-------------REFGSVDDENKPIWMHAEEREECKGK 435
Query: 649 LEH-----EYGPYH-------PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLG 696
+ EYG ++ P NL Y G+ EA + LE ++R K G
Sbjct: 436 QKDGSSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF-EAAETLE-EAALRSRKQG 493
Query: 697 TANPDVDDEKRRLSELLKEAGRVRSRK 723
N K+R++E+L + V R+
Sbjct: 494 LDNV----HKQRVAEVLNDPENVEKRR 516
Score = 53.9 bits (128), Expect = 2e-06
Identities = 44/170 (25%), Positives = 65/170 (37%), Gaps = 19/170 (11%)
Query: 568 DSPGQ----QSSIAGIEAQMG---------------VMYYMLGNYTESYNTLKNAITKLR 608
D PGQ Q S A AQ G + Y G Y + K A+ L
Sbjct: 181 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 240
Query: 609 AIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLA 668
+ LN + L + +A L +A +I E G HP +NLA
Sbjct: 241 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLA 300
Query: 669 GTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAGR 718
Y G+ EA + + + +RE+ LG +PDV + L+ L + G+
Sbjct: 301 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGK 350
Score = 50.4 bits (119), Expect = 2e-05
Identities = 44/199 (22%), Positives = 82/199 (41%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y ++
Sbjct: 212 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAA 271
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
N L +A+ + + LN + + + + EA L + A I E G H
Sbjct: 272 NLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDH 331
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ +NLA G+ +E + + + + KLG +P+V K L+ + G
Sbjct: 332 PDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQG 391
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + + E L A+ R
Sbjct: 392 KFKQAETLYKEILTRAHER 410
Score = 50.1 bits (118), Expect = 2e-05
Identities = 53/257 (20%), Positives = 105/257 (40%), Gaps = 60/257 (23%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + G+Y A+P+ ++++E L K +GH L Y
Sbjct: 212 LHNLVIQYASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVY 261
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
+ +++ + ++ + LG P V T +A + ++ EAE LC+ AL+
Sbjct: 262 RDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 321
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSI 457
I + +++G K + + A + L ++A++ Q
Sbjct: 322 IRE--------------KVLG-----KDHPDVAKQ---LNNLALLCQNQ----------- 348
Query: 458 GDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKS-YC 516
+Y+E + Y++AL +++T G + P V LA + + GK K++++ Y
Sbjct: 349 -------GKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYK 401
Query: 517 DSALRIYENPMPGVNPE 533
+ R +E V+ E
Sbjct: 402 EILTRAHEREFGSVDDE 418
Score = 47.4 bits (111), Expect = 1e-04
Identities = 66/323 (20%), Positives = 132/323 (40%), Gaps = 16/323 (4%)
Query: 228 NSAESALDKPERAPILLKQARDLI---SSGDNPQKALELALQAMNLLEKLGNGKPSLELV 284
++A +A P L+ +L+ +S + A+ L QA+ LEK +G ++
Sbjct: 193 SAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVA 251
Query: 285 MCLHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLE 344
L++ A +Y + +Y +A +L ++ I + H A A L Y G+ +
Sbjct: 252 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHP-AVAATLNNLAVLYGKRGKYK 310
Query: 345 NSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSS 404
+ E++ +VLG+ P V + +A +++E E Q AL+I++
Sbjct: 311 EAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLG 370
Query: 405 APSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSIGDTYLSM 464
A + + +G + A E L ++ E E SVD ++
Sbjct: 371 PDDPNVAKTKNNLASCYLKQGKFKQA-ETLY---KEILTRAHEREFGSVDDENKPIWMHA 426
Query: 465 SRYDEAVFAYEKALTV------FKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDS 518
+E + + +K K ++ P V + L L+ R GK + +++ ++
Sbjct: 427 EEREECKGKQKDGSSFGEYGGWYKACKVDS-PTVTTTLKNLGALYRRQGKFEAAETLEEA 485
Query: 519 ALRIYENPMPGVNPEEIASGLTN 541
ALR + + V+ + +A L +
Sbjct: 486 ALRSRKQGLDNVHKQRVAEVLND 508
>KLC2_HUMAN (Q9H0B6) Kinesin light chain 2 (KLC 2)
Length = 622
Score = 65.9 bits (159), Expect = 4e-10
Identities = 48/198 (24%), Positives = 93/198 (46%), Gaps = 6/198 (3%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y ++Y E
Sbjct: 199 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKE 258
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL + + G++HPAV + LA L+ + GK KE++ C AL I E +
Sbjct: 259 AAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 318
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+P ++A L+N++ + ++ + E+ ++AL IY G ++A + + Y
Sbjct: 319 FHP-DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 377
Query: 589 MLGNYTESYNTLKNAITK 606
G Y ++ K +T+
Sbjct: 378 KQGKYQDAETLYKEILTR 395
Score = 52.8 bits (125), Expect = 3e-06
Identities = 35/134 (26%), Positives = 55/134 (40%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y G Y + K A+ L + LN + L + EA L +
Sbjct: 206 IQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLND 265
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A +I E G HP +NLA Y G+ EA + + + +RE+ LG +PDV
Sbjct: 266 ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAK 325
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 326 QLSNLALLCQNQGK 339
Score = 50.4 bits (119), Expect = 2e-05
Identities = 81/401 (20%), Positives = 156/401 (38%), Gaps = 58/401 (14%)
Query: 192 KNDKPLLRKQTKGVASGVKSLKSSPLGKSVSLNRVENSAESALDKPERAPILLKQARDLI 251
+++K LR Q + + + L+ G L R E A + L++ ++ + + Q R L
Sbjct: 89 ESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQ-AVAQLEEEKQHLLFMSQIRKLD 147
Query: 252 SS-------GDNPQKALELAL---QAMNLLEKLGNGKPSLE--------LVMCLHVTAAI 293
GD P+ L+ + G G S + + LH
Sbjct: 148 EDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQ 207
Query: 294 YCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTYAMLGQLE 344
Y + G+Y A+P+ ++++E L K +GH L Y + +
Sbjct: 208 YASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVYRDQNKYK 257
Query: 345 NSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSS 404
+ + ++ + LG+ P V T +A + ++ EAE LC+ AL+I +
Sbjct: 258 EAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG 317
Query: 405 APSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVA---NGQEVEVASVDCSIGDTY 461
+ A + L+ +G E +E+ ++ + A + VA ++ Y
Sbjct: 318 KFHPDVAKQLSNLALLCQNQGKAE-EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCY 376
Query: 462 LSMSRYDEAVFAYEKALT-----VFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYC 516
L +Y +A Y++ LT F + G+N P +++ + K ++S Y
Sbjct: 377 LKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKP----IWMHAEEREESKDKRRDSAPYG 432
Query: 517 D--SALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKA 555
+ S + + P VN + L ++ A+Y +LE A
Sbjct: 433 EYGSWYKACKVDSPTVN-----TTLRSLGALYRRQGKLEAA 468
Score = 49.7 bits (117), Expect = 3e-05
Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y E+
Sbjct: 201 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAA 260
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
+ L +A+ K + LN + + + + EA L + A I E G +H
Sbjct: 261 HLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFH 320
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ SNLA G+ +E + + +LG +P+V K L+ + G
Sbjct: 321 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 380
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + + E L A+ +
Sbjct: 381 KYQDAETLYKEILTRAHEK 399
>KLC1_MOUSE (O88447) Kinesin light chain 1 (KLC 1)
Length = 537
Score = 65.9 bits (159), Expect = 4e-10
Identities = 77/349 (22%), Positives = 143/349 (40%), Gaps = 43/349 (12%)
Query: 398 IHKANSSAPSLEEAAD-----RRLMGLILD--TKGNHEAALEHL--VLASMAMVANGQEV 448
I ++SSA + + + R L L++ ++G +E A+ L + +
Sbjct: 187 IQHSDSSAAAARQGYEIPARLRTLHNLVIQYASQGRYEVAVPSCKQALEDLEKTSGHDHP 246
Query: 449 EVASVDCSIGDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGK 508
+VA++ + Y ++Y +A AL + + G +HPAV + LA L+ + GK
Sbjct: 247 DVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGK 306
Query: 509 IKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYND 568
KE++ C AL I E + G + ++A L N++ + ++ + E+ Q+AL IY
Sbjct: 307 YKEAEPLCKRALEIREKVL-GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQT 365
Query: 569 --SPGQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMG 626
P + ++A + + Y G + ++ K +T+ + G
Sbjct: 366 KLGPDRTPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEA-------------EFG 412
Query: 627 LACVQLYAFGEATELFEEAKSILEH-----EYGPYH-------PETLGVYSNLAGTYDAI 674
+ E EE K + EYG ++ P NL Y
Sbjct: 413 SVDDENKPIWMHAEEREECKGKQKDGSAFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQ 472
Query: 675 GRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAGRVRSRK 723
G+ EA + LE ++R K G N K+R++E+L + + R+
Sbjct: 473 GKF-EAAETLE-EAAMRSRKQGLDNV----HKQRVAEVLNDPESMEKRR 515
Score = 46.2 bits (108), Expect = 3e-04
Identities = 58/295 (19%), Positives = 118/295 (39%), Gaps = 36/295 (12%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + G+Y A+P ++++E L K +GH L Y
Sbjct: 210 LHNLVIQYASQGRYEVAVPSCKQALE----------DLEKTSGHDHPDVATMLNILALVY 259
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
+ +++ + ++ + LG P V T +A + ++ EAE LC+ AL+
Sbjct: 260 RDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 319
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAM----VANGQEVEVASV 453
I + + A + L+ +G +E +E+ ++ + + + VA
Sbjct: 320 IREKVLGKDHPDVAKQLNNLALLCQNQGKYE-EVEYYYQRALGIYQTKLGPDRTPNVAKT 378
Query: 454 DCSIGDTYLSMSRYDEAVFAYEKALT-----VFKTGKGENHPAVGSVFVRLADLHNRTGK 508
++ YL ++ +A Y++ LT F + EN P +++ + GK
Sbjct: 379 KNNLASCYLKQGKFKQAETLYKEILTRAHEAEFGSVDDENKP----IWMHAEEREECKGK 434
Query: 509 IKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKAL 563
K+ ++ + Y+ V+ + + L N+ A+Y + E A L + A+
Sbjct: 435 QKDGSAFGEYG-GWYK--ACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAM 486
Score = 44.7 bits (104), Expect = 0.001
Identities = 71/355 (20%), Positives = 143/355 (40%), Gaps = 26/355 (7%)
Query: 228 NSAESALDKPERAPILLKQARDLI---SSGDNPQKALELALQAMNLLEKLGNGKPSLELV 284
+S+ +A + P L+ +L+ +S + A+ QA+ LEK +G ++
Sbjct: 191 DSSAAAARQGYEIPARLRTLHNLVIQYASQGRYEVAVPSCKQALEDLEKT-SGHDHPDVA 249
Query: 285 MCLHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLE 344
L++ A +Y + +Y +A +L ++ I + H A A L Y G+ +
Sbjct: 250 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHP-AVAATLNNLAVLYGKRGKYK 308
Query: 345 NSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKAN-- 402
+ E++ +VLG+ P V + +A +++E E Q AL I++
Sbjct: 309 EAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLG 368
Query: 403 -SSAPSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSIGDTY 461
P++ + + + K L +L E E SVD +
Sbjct: 369 PDRTPNVAKTKNNLASCYLKQGKFKQAETLYKEILT------RAHEAEFGSVDDENKPIW 422
Query: 462 LSMSRYDEAV------FAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSY 515
+ +E A+ + +K K ++ P V + L L+ R GK + +++
Sbjct: 423 MHAEEREECKGKQKDGSAFGEYGGWYKACKVDS-PTVTTTLKNLGALYRRQGKFEAAETL 481
Query: 516 CDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSP 570
++A+R + + V+ + +A L + ESM E ++ + L ++ Y P
Sbjct: 482 EEAAMRSRKQGLDNVHKQRVAEVLNDP----ESM-EKRRSRESLNMDVVKYESGP 531
>KLC1_HUMAN (Q07866) Kinesin light chain 1 (KLC 1)
Length = 569
Score = 65.5 bits (158), Expect = 5e-10
Identities = 73/327 (22%), Positives = 134/327 (40%), Gaps = 37/327 (11%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y ++Y +
Sbjct: 210 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKD 269
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL + + G++HPAV + LA L+ + GK KE++ C AL I E + G
Sbjct: 270 AANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL-G 328
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+ ++A L N++ + ++ + E+ Q+AL IY G ++A + + Y
Sbjct: 329 KDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYL 388
Query: 589 MLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSI 648
G + ++ K +T+ + G + E EE K
Sbjct: 389 KQGKFKQAETLYKEILTRAHE-------------REFGSVDDENKPIWMHAEEREECKGK 435
Query: 649 LEH-----EYGPYH-------PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLG 696
+ EYG ++ P NL Y G+ EA + LE ++R K G
Sbjct: 436 QKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF-EAAETLE-EAAMRSRKQG 493
Query: 697 TANPDVDDEKRRLSELLKEAGRVRSRK 723
N K+R++E+L + + R+
Sbjct: 494 LDNV----HKQRVAEVLNDPENMEKRR 516
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/170 (25%), Positives = 65/170 (37%), Gaps = 19/170 (11%)
Query: 568 DSPGQ----QSSIAGIEAQMG---------------VMYYMLGNYTESYNTLKNAITKLR 608
D PGQ Q S A AQ G + Y G Y + K A+ L
Sbjct: 181 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 240
Query: 609 AIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLA 668
+ LN + L + +A L +A +I E G HP +NLA
Sbjct: 241 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 300
Query: 669 GTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAGR 718
Y G+ EA + + + +RE+ LG +PDV + L+ L + G+
Sbjct: 301 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGK 350
Score = 51.6 bits (122), Expect = 7e-06
Identities = 45/199 (22%), Positives = 82/199 (40%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y ++
Sbjct: 212 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAA 271
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
N L +A+ K + LN + + + + EA L + A I E G H
Sbjct: 272 NLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDH 331
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ +NLA G+ +E + + + + KLG +P+V K L+ + G
Sbjct: 332 PDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQG 391
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + + E L A+ R
Sbjct: 392 KFKQAETLYKEILTRAHER 410
Score = 50.4 bits (119), Expect = 2e-05
Identities = 53/257 (20%), Positives = 106/257 (40%), Gaps = 60/257 (23%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + G+Y A+P+ ++++E L K +GH L Y
Sbjct: 212 LHNLVIQYASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVY 261
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
+ +++ + ++ + LG+ P V T +A + ++ EAE LC+ AL+
Sbjct: 262 RDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 321
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSI 457
I + +++G K + + A + L ++A++ Q
Sbjct: 322 IRE--------------KVLG-----KDHPDVAKQ---LNNLALLCQNQ----------- 348
Query: 458 GDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKS-YC 516
+Y+E + Y++AL +++T G + P V LA + + GK K++++ Y
Sbjct: 349 -------GKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYK 401
Query: 517 DSALRIYENPMPGVNPE 533
+ R +E V+ E
Sbjct: 402 EILTRAHEREFGSVDDE 418
Score = 47.0 bits (110), Expect = 2e-04
Identities = 65/323 (20%), Positives = 132/323 (40%), Gaps = 16/323 (4%)
Query: 228 NSAESALDKPERAPILLKQARDLI---SSGDNPQKALELALQAMNLLEKLGNGKPSLELV 284
++A +A P L+ +L+ +S + A+ L QA+ LEK +G ++
Sbjct: 193 SAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVA 251
Query: 285 MCLHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLE 344
L++ A +Y + +Y +A +L ++ I + H A A L Y G+ +
Sbjct: 252 TMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHP-AVAATLNNLAVLYGKRGKYK 310
Query: 345 NSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSS 404
+ E++ +VLG+ P V + +A +++E E Q AL+I++
Sbjct: 311 EAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLG 370
Query: 405 APSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSIGDTYLSM 464
A + + +G + A E L ++ E E SVD ++
Sbjct: 371 PDDPNVAKTKNNLASCYLKQGKFKQA-ETLY---KEILTRAHEREFGSVDDENKPIWMHA 426
Query: 465 SRYDEAVFAYEKALTV------FKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDS 518
+E + + +K K ++ P V + L L+ R GK + +++ ++
Sbjct: 427 EEREECKGKQKDGTSFGEYGGWYKACKVDS-PTVTTTLKNLGALYRRQGKFEAAETLEEA 485
Query: 519 ALRIYENPMPGVNPEEIASGLTN 541
A+R + + V+ + +A L +
Sbjct: 486 AMRSRKQGLDNVHKQRVAEVLND 508
>KLC2_MOUSE (O88448) Kinesin light chain 2 (KLC 2)
Length = 599
Score = 64.7 bits (156), Expect = 9e-10
Identities = 47/198 (23%), Positives = 93/198 (46%), Gaps = 6/198 (3%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y ++Y +
Sbjct: 198 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKD 257
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL + + G++HPAV + LA L+ + GK KE++ C AL I E +
Sbjct: 258 AAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 317
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+P ++A L+N++ + ++ + E+ ++AL IY G ++A + + Y
Sbjct: 318 FHP-DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 376
Query: 589 MLGNYTESYNTLKNAITK 606
G Y ++ K +T+
Sbjct: 377 KQGKYQDAETLYKEILTR 394
Score = 51.6 bits (122), Expect = 7e-06
Identities = 34/134 (25%), Positives = 55/134 (40%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y G Y + K A+ L + LN + L + +A L +
Sbjct: 205 IQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLND 264
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A +I E G HP +NLA Y G+ EA + + + +RE+ LG +PDV
Sbjct: 265 ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAK 324
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 325 QLSNLALLCQNQGK 338
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/333 (20%), Positives = 131/333 (38%), Gaps = 46/333 (13%)
Query: 192 KNDKPLLRKQTKGVASGVKSLKSSPLGKSVSLNRVENSAESALDKPERAPILLKQARDLI 251
+++K LR Q + + + L+ G L R E A + L++ ++ + + Q R L
Sbjct: 89 ESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQ-AVAQLEEEKQHLLFMSQIRKLD 147
Query: 252 S------SGDNPQKALELAL---QAMNLLEKLGNGKPSLE--------LVMCLHVTAAIY 294
GD P+ +L+ + G G + + + LH Y
Sbjct: 148 EMLPQEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQY 207
Query: 295 CNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTYAMLGQLEN 345
+ G+Y A+P+ ++++E L K +GH L Y + ++
Sbjct: 208 ASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVYRDQNKYKD 257
Query: 346 SIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSSA 405
+ + ++ + LG+ P V T +A + ++ EAE LC+ AL+I +
Sbjct: 258 AAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 317
Query: 406 PSLEEAADRRLMGLILDTKGNHEAALEHLVLASMAMVA---NGQEVEVASVDCSIGDTYL 462
+ A + L+ +G E +E+ ++ + A + VA ++ YL
Sbjct: 318 FHPDVAKQLSNLALLCQNQGKAE-EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 376
Query: 463 SMSRYDEAVFAYEKALT-----VFKTGKGENHP 490
+Y +A Y++ LT F + GEN P
Sbjct: 377 KQGKYQDAETLYKEILTRAHEKEFGSVNGENKP 409
Score = 48.5 bits (114), Expect = 6e-05
Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 1/199 (0%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y Y ++
Sbjct: 200 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAA 259
Query: 598 NTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYH 657
+ L +A+ K + LN + + + + EA L + A I E G +H
Sbjct: 260 HLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFH 319
Query: 658 PETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAG 717
P+ SNLA G+ +E + + +LG +P+V K L+ + G
Sbjct: 320 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 379
Query: 718 RVRSRKVMSLENLLDANAR 736
+ + + + E L A+ +
Sbjct: 380 KYQDAETLYKEILTRAHEK 398
>KLC_LOLPE (P46825) Kinesin light chain (KLC)
Length = 571
Score = 63.5 bits (153), Expect = 2e-09
Identities = 48/198 (24%), Positives = 91/198 (45%), Gaps = 6/198 (3%)
Query: 414 RRLMGLILD--TKGNHEAALE--HLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDE 469
R L L++ ++G +E A+ L + + +VA++ + Y +Y E
Sbjct: 221 RTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQGKYKE 280
Query: 470 AVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPG 529
A AL + + G +HPAV + LA L+ + GK K+++ C AL I E + G
Sbjct: 281 AANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALVIREKVL-G 339
Query: 530 VNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYY 588
+ ++A L N++ + ++ + E+ + Q+AL IY G ++A + + Y
Sbjct: 340 KDHPDVAKQLNNLALLCQNQGKYEEVERYYQRALEIYQKELGPDDPNVAKTKNNLASAYL 399
Query: 589 MLGNYTESYNTLKNAITK 606
G Y ++ K +T+
Sbjct: 400 KQGKYKQAEILYKEVLTR 417
Score = 58.9 bits (141), Expect = 5e-08
Identities = 51/212 (24%), Positives = 86/212 (40%), Gaps = 9/212 (4%)
Query: 498 RLADLHNRT------GKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNE 551
RL LHN G+ + + C AL E +P+ +A+ L ++ +Y +
Sbjct: 219 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNILALVYRDQGK 277
Query: 552 LEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAI 610
++A LL AL I + G ++A + V+Y G Y ++ K A+ +
Sbjct: 278 YKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALVIREKV 337
Query: 611 GEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGT 670
K + LN + L C + E ++ A I + E GP P +NLA
Sbjct: 338 LGKDHPDVAKQLNNLALLCQNQGKYEEVERYYQRALEIYQKELGPDDPNVAKTKNNLASA 397
Query: 671 YDAIGRLDEA-IQILEYVVSVREEKLGTANPD 701
Y G+ +A I E + E++ G + D
Sbjct: 398 YLKQGKYKQAEILYKEVLTRAHEKEFGKVDDD 429
Score = 53.5 bits (127), Expect = 2e-06
Identities = 35/134 (26%), Positives = 55/134 (40%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y G Y + K A+ L + LN + L + EA L +
Sbjct: 228 IQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQGKYKEAANLLND 287
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A I E GP HP +NLA Y G+ +A + + + +RE+ LG +PDV
Sbjct: 288 ALGIREKTLGPDHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALVIREKVLGKDHPDVAK 347
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 348 QLNNLALLCQNQGK 361
Score = 50.8 bits (120), Expect = 1e-05
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 3/200 (1%)
Query: 539 LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SIAGIEAQMGVMYYMLGNYTESY 597
L N+ Y S E A+ L ++AL + G +A + + ++Y G Y E+
Sbjct: 223 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQGKYKEAA 282
Query: 598 NTLKNAI-TKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPY 656
N L +A+ + + +G + + LN + + + + +A L + A I E G
Sbjct: 283 NLLNDALGIREKTLGPDHPA-VAATLNNLAVLYGKRGKYKDAEPLCKRALVIREKVLGKD 341
Query: 657 HPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEA 716
HP+ +NLA G+ +E + + + + +++LG +P+V K L+ +
Sbjct: 342 HPDVAKQLNNLALLCQNQGKYEEVERYYQRALEIYQKELGPDDPNVAKTKNNLASAYLKQ 401
Query: 717 GRVRSRKVMSLENLLDANAR 736
G+ + +++ E L A+ +
Sbjct: 402 GKYKQAEILYKEVLTRAHEK 421
Score = 48.9 bits (115), Expect = 5e-05
Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 37/295 (12%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + G+Y A+P+ ++++E L K +GH L Y
Sbjct: 223 LHNLVIQYASQGRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVY 272
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
G+ + + + ++ + LG P V T +A + ++ +AE LC+ AL
Sbjct: 273 RDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALV 332
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAALEHL--VLASMAMVANGQEVEVASVDC 455
I + + A + L+ +G +E + L + VA
Sbjct: 333 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVERYYQRALEIYQKELGPDDPNVAKTKN 392
Query: 456 SIGDTYLSMSRYDEAVFAYEKALT-----VFKTGKGENHPAVGSVFVRLADLHNRTGKIK 510
++ YL +Y +A Y++ LT F +N P ++++ + K K
Sbjct: 393 NLASAYLKQGKYKQAEILYKEVLTRAHEKEFGKVDDDNKP----IWMQAEEREENKAKYK 448
Query: 511 ESKSYCD--SALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKAL 563
+ D S L+ + V+ + + L N+ A+Y + E A L + AL
Sbjct: 449 DGAPQPDYGSWLKAVK-----VDSPTVTTTLKNLGALYRRQGKYEAAETLEECAL 498
Score = 47.8 bits (112), Expect = 1e-04
Identities = 63/307 (20%), Positives = 122/307 (39%), Gaps = 14/307 (4%)
Query: 241 PILLKQARDLI---SSGDNPQKALELALQAMNLLEKLGNGKPSLELVMCLHVTAAIYCNL 297
P L+ +L+ +S + A+ L QA+ LEK +G ++ L++ A +Y +
Sbjct: 217 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQ 275
Query: 298 GQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFEVQ 357
G+Y EA +L ++ I H A A L Y G+ +++ ++
Sbjct: 276 GKYKEAANLLNDALGIREKTLGPDHP-AVAATLNNLAVLYGKRGKYKDAEPLCKRALVIR 334
Query: 358 RQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALDIHKANSSAPSLEEAADRRLM 417
+VLG+ P V + +A +++E ER Q AL+I++ A + +
Sbjct: 335 EKVLGKDHPDVAKQLNNLALLCQNQGKYEEVERYYQRALEIYQKELGPDDPNVAKTKNNL 394
Query: 418 GLILDTKGNHEAALEHLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRYDEAVFAYEKA 477
+G ++ A + ++ E E VD ++ +E Y+
Sbjct: 395 ASAYLKQGKYKQA----EILYKEVLTRAHEKEFGKVDDDNKPIWMQAEEREENKAKYKDG 450
Query: 478 LTVFKTGKG-----ENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPGVNP 532
G + P V + L L+ R GK + +++ + ALR ++ + V
Sbjct: 451 APQPDYGSWLKAVKVDSPTVTTTLKNLGALYRRQGKYEAAETLEECALRSRKSALEVVRQ 510
Query: 533 EEIASGL 539
+I+ L
Sbjct: 511 TKISDVL 517
>KLC_STRPU (Q05090) Kinesin light chain (KLC)
Length = 686
Score = 63.2 bits (152), Expect = 2e-09
Identities = 58/234 (24%), Positives = 95/234 (39%), Gaps = 11/234 (4%)
Query: 482 KTGKGENHPAVGSVFV--RLADLHNRTGKIKESKSY------CDSALRIYENPMPGVNPE 533
+TG G A G + RL LHN + Y C AL E +P+
Sbjct: 196 QTGSGSVSAAAGGYEIPARLRTLHNLVIQYASQSRYEVAVPLCKQALEDLEKTSGHDHPD 255
Query: 534 EIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPG-QQSSIAGIEAQMGVMYYMLGN 592
+A+ L ++ +Y N+ ++A LL AL I + G ++A + V+Y G
Sbjct: 256 -VATMLNILALVYRDQNKYKEAGNLLHDALAIREKTLGPDHPAVAATLNNLAVLYGKRGK 314
Query: 593 YTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKSILEHE 652
Y E+ K A+ + K + LN + L C + E ++ A I E +
Sbjct: 315 YKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEWYYQRALEIYEKK 374
Query: 653 YGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVS-VREEKLGTANPDVDDE 705
GP P +NLA Y G+ A + + V++ E + G + D D++
Sbjct: 375 LGPDDPNVAKTKNNLAAAYLKQGKYKAAETLYKQVLTRAHEREFGLSADDKDNK 428
Score = 62.8 bits (151), Expect = 3e-09
Identities = 42/159 (26%), Positives = 75/159 (46%), Gaps = 2/159 (1%)
Query: 449 EVASVDCSIGDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGK 508
+VA++ + Y ++Y EA AL + + G +HPAV + LA L+ + GK
Sbjct: 255 DVATMLNILALVYRDQNKYKEAGNLLHDALAIREKTLGPDHPAVAATLNNLAVLYGKRGK 314
Query: 509 IKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYND 568
KE++ C AL I E + G + ++A L N++ + ++ + E+ Q+AL IY
Sbjct: 315 YKEAEPLCKRALEIREKVL-GKDHPDVAKQLNNLALLCQNQGKYEEVEWYYQRALEIYEK 373
Query: 569 SPG-QQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITK 606
G ++A + + Y G Y + K +T+
Sbjct: 374 KLGPDDPNVAKTKNNLAAAYLKQGKYKAAETLYKQVLTR 412
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/134 (26%), Positives = 55/134 (40%)
Query: 585 VMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEE 644
+ Y Y + K A+ L + LN + L + EA L +
Sbjct: 223 IQYASQSRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAGNLLHD 282
Query: 645 AKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANPDVDD 704
A +I E GP HP +NLA Y G+ EA + + + +RE+ LG +PDV
Sbjct: 283 ALAIREKTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAK 342
Query: 705 EKRRLSELLKEAGR 718
+ L+ L + G+
Sbjct: 343 QLNNLALLCQNQGK 356
Score = 51.6 bits (122), Expect = 7e-06
Identities = 51/226 (22%), Positives = 95/226 (41%), Gaps = 13/226 (5%)
Query: 523 YENPMPGVNPEEIASG----------LTNVSAIYESMNELEKALKLLQKALLIYNDSPGQ 572
Y P G A+G L N+ Y S + E A+ L ++AL + G
Sbjct: 192 YPQPQTGSGSVSAAAGGYEIPARLRTLHNLVIQYASQSRYEVAVPLCKQALEDLEKTSGH 251
Query: 573 QS-SIAGIEAQMGVMYYMLGNYTESYNTLKNAIT-KLRAIGEKKSSFIGIALNQMGLACV 630
+A + + ++Y Y E+ N L +A+ + + +G + + LN + +
Sbjct: 252 DHPDVATMLNILALVYRDQNKYKEAGNLLHDALAIREKTLGPDHPA-VAATLNNLAVLYG 310
Query: 631 QLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSV 690
+ + EA L + A I E G HP+ +NLA G+ +E + + +
Sbjct: 311 KRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEWYYQRALEI 370
Query: 691 REEKLGTANPDVDDEKRRLSELLKEAGRVRSRKVMSLENLLDANAR 736
E+KLG +P+V K L+ + G+ ++ + + + L A+ R
Sbjct: 371 YEKKLGPDDPNVAKTKNNLAAAYLKQGKYKAAETLYKQVLTRAHER 416
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/182 (24%), Positives = 79/182 (42%), Gaps = 3/182 (1%)
Query: 384 QFDEAERLCQMALDIHKANSSAPSLEEAADRRLMGLILDTKGNHEAA--LEHLVLASMAM 441
+++ A LC+ AL+ + S + A ++ L+ + ++ A L H LA
Sbjct: 230 RYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAGNLLHDALAIREK 289
Query: 442 VANGQEVEVASVDCSIGDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLAD 501
VA+ ++ Y +Y EA ++AL + + G++HP V LA
Sbjct: 290 TLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLAL 349
Query: 502 LHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQK 561
L GK +E + Y AL IYE + G + +A N++A Y + + A L ++
Sbjct: 350 LCQNQGKYEEVEWYYQRALEIYEKKL-GPDDPNVAKTKNNLAAAYLKQGKYKAAETLYKQ 408
Query: 562 AL 563
L
Sbjct: 409 VL 410
Score = 38.9 bits (89), Expect = 0.050
Identities = 41/204 (20%), Positives = 74/204 (36%), Gaps = 21/204 (10%)
Query: 287 LHVTAAIYCNLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQ---------LGDTY 337
LH Y + +Y A+P+ ++++E L K +GH L Y
Sbjct: 218 LHNLVIQYASQSRYEVAVPLCKQALE----------DLEKTSGHDHPDVATMLNILALVY 267
Query: 338 AMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLCQMALD 397
+ + + ++ + LG P V T +A + ++ EAE LC+ AL+
Sbjct: 268 RDQNKYKEAGNLLHDALAIREKTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 327
Query: 398 IHKANSSAPSLEEAADRRLMGLILDTKGNHEAA--LEHLVLASMAMVANGQEVEVASVDC 455
I + + A + L+ +G +E L + VA
Sbjct: 328 IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEWYYQRALEIYEKKLGPDDPNVAKTKN 387
Query: 456 SIGDTYLSMSRYDEAVFAYEKALT 479
++ YL +Y A Y++ LT
Sbjct: 388 NLAAAYLKQGKYKAAETLYKQVLT 411
>KA43_HUMAN (Q96AY4) TPR repeat containing protein KIAA1043
Length = 1642
Score = 52.8 bits (125), Expect = 3e-06
Identities = 54/241 (22%), Positives = 108/241 (44%), Gaps = 21/241 (8%)
Query: 457 IGDTYLSMSRYDEAVFAYEKALTVFKTGKG-ENHPAVGSVFVRLADLHNRTGKIKESKSY 515
+G T ++M+ +EA+ +E+ L + + G E+ G + L D + G +E+ Y
Sbjct: 1 MGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKY 60
Query: 516 CDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQSS 575
+ L + ++ + + GL N + +M L++AL +K L++ ++ G+ +
Sbjct: 61 YEQYLSVAQSLNRMQDQAKAYRGLGNG---HRAMGSLQQALVCFEKRLVVAHEL-GEAFN 116
Query: 576 IAGIEAQMGVMYYMLGNYTESYNTLKNAIT-----KLRAIGEKKSSFIGIALNQMGLACV 630
A ++G ++ LGNY ++ + L+ + K RA+ + +G QMG
Sbjct: 117 KAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDT 176
Query: 631 QLYAFGEATELFEEAKSILEHEYGPYHPETLG-VYSNLAGTYDAIGRLDEAIQILEYVVS 689
L ++ EE + P G Y NL TY+++G + A+ E +S
Sbjct: 177 ALQYHQLDLQIAEETNN----------PTCQGRAYGNLGLTYESLGTFERAVVYQEQHLS 226
Query: 690 V 690
+
Sbjct: 227 I 227
Score = 43.1 bits (100), Expect = 0.003
Identities = 65/319 (20%), Positives = 124/319 (38%), Gaps = 32/319 (10%)
Query: 296 NLGQYNEAIPILERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFE 355
N+ EAI E+ + + + L + + LGD Y LG E +I Y
Sbjct: 7 NMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLS 66
Query: 356 VQRQVLGETDPR-----VGETCRYVAEANVQALQFDEAERLCQMALDIHKANSSAPSLEE 410
V + + D +G R + + F E+ +A ++ +A + A + E
Sbjct: 67 VAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCF---EKRLVVAHELGEAFNKAQAYGE 123
Query: 411 AADRRLMGLILDTKGNHEAA---LEHLVLASMAMVANGQEVEVASVDCSIGDTYLSMSRY 467
+G + GN+E A LE + + M E + A C +G Y M Y
Sbjct: 124 ------LGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAA---CGLGGVYQQMGEY 174
Query: 468 DEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPM 527
D A+ ++ L + + + N G + L + G + + Y + L I
Sbjct: 175 DTALQYHQLDLQIAE--ETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSI----- 227
Query: 528 PGVNPEEIASGLTNVSAI---YESMNELEKALKLLQKALLIYNDSPGQQSSIAGIEAQMG 584
++A+ + S++ + ++ +A+ LQ+ L + + G++ A I +G
Sbjct: 228 -AAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRL-AEQLGRREDEAKIRHGLG 285
Query: 585 VMYYMLGNYTESYNTLKNA 603
+ + GN E+ + L A
Sbjct: 286 LSLWASGNLEEAQHQLYRA 304
Score = 38.9 bits (89), Expect = 0.050
Identities = 43/196 (21%), Positives = 76/196 (37%), Gaps = 11/196 (5%)
Query: 42 RGQNGGPNFPVDGVIEPSIEQLYENVCDMQSSDQSPSRKSFGSDGDESRIDSELRQLVGG 101
+G PN PV + PS ++ V + SSD S +S + E +
Sbjct: 1261 KGSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESNPKLDP 1320
Query: 102 RMREVEIMEEEVEVEVEKERGGSSSGEISSGVGGLSSNEKKLDKVHEIQSATTSSVSTEK 161
+ +I+EE + ER S G++S K + +Q+ ++++V
Sbjct: 1321 QELAQKILEETQSHLIAVERLQRSGGQVS----------KSNNPEDGVQAPSSTAVFRAS 1370
Query: 162 SVKALNSQLDASPKSKPKGKSPPAKAPLERKNDKPLLRKQTKGVASGVKSLKSSPLGKSV 221
A + + + KS+P + K P R + P + + S+K SP S
Sbjct: 1371 ETSAFSRPVLSHQKSQPSPVTVKPKPP-ARSSSLPKVSSGYSSPTTSEMSIKDSPSQHSG 1429
Query: 222 SLNRVENSAESALDKP 237
+ +S S LD+P
Sbjct: 1430 RPSPGCDSQTSQLDQP 1445
Score = 33.1 bits (74), Expect = 2.7
Identities = 21/69 (30%), Positives = 34/69 (48%), Gaps = 1/69 (1%)
Query: 625 MGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLG-VYSNLAGTYDAIGRLDEAIQI 683
MG+ + + EA FE+ ++L+ G G Y NL Y+A+G +EAI+
Sbjct: 1 MGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKY 60
Query: 684 LEYVVSVRE 692
E +SV +
Sbjct: 61 YEQYLSVAQ 69
>NFM_HUMAN (P07197) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Neurofilament 3)
Length = 915
Score = 51.2 bits (121), Expect = 1e-05
Identities = 53/188 (28%), Positives = 81/188 (42%), Gaps = 15/188 (7%)
Query: 83 GSDGDESRIDSELRQLVGGRMREVEIMEEEVEVEVEKERGGSSSGEISSGVGGLSSNEKK 142
G +E + E + G + + E E E EKE G GE + G + K+
Sbjct: 524 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE 583
Query: 143 LDKVHE--IQSATTSSVSTEKSVKALNSQLDASPKS--KPKGKSPPAKAPLERKNDKPLL 198
KV E + AT + + V+ PKS + KGKSP K+P+E K P+
Sbjct: 584 EKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 643
Query: 199 RKQTKGVASGVKSLKSSPL---GKS-VSLNRVENSAESALDKPERAPILLKQARDLISSG 254
+ + G + SP+ GKS VS + VE A+S + K +P+ ++A+ G
Sbjct: 644 KSPVE--EKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK---SPV--EEAKSKAEVG 696
Query: 255 DNPQKALE 262
QK E
Sbjct: 697 KGEQKEEE 704
>OGT1_RAT (P56558) UDP-N-acetylglucosamine--peptide
N-acetylglucosaminyltransferase 110 kDa subunit (EC
2.4.1.-) (O-GlcNAc transferase p110 subunit)
Length = 1036
Score = 48.1 bits (113), Expect = 8e-05
Identities = 88/420 (20%), Positives = 157/420 (36%), Gaps = 86/420 (20%)
Query: 307 LERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFEVQRQVLGETDP 366
L+RS + Q LA+ + LG+ Y GQL+ +I Y ++ + D
Sbjct: 61 LDRSAHFSTLAIKQNPLLAE--AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI---DG 115
Query: 367 RVGETCRYVA--------EANVQALQFDEAERLCQMALDIHKANSSAPSLEEAADRRLMG 418
+ VA +A V ALQ++ L + D+ + LEEA L
Sbjct: 116 YINLAAALVAAGDMEGAVQAYVSALQYNPD--LYCVRSDLGNLLKALGRLEEAKACYLKA 173
Query: 419 LILDTKGNHEAALEHLVLASMAM----VANGQEVEVASVDCSIGDTYLSMSR-------Y 467
+ +T+ N A +L A +A + ++D + D Y+++ +
Sbjct: 174 I--ETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 231
Query: 468 DEAVFAYEKALTV---------------FKTG-----------KGENHPAVGSVFVRLAD 501
D AV AY +AL++ ++ G E P + LA+
Sbjct: 232 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLAN 291
Query: 502 LHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQK 561
G + E++ ++ALR+ A L N++ I +E+A++L +K
Sbjct: 292 ALKEKGSVAEAEDCYNTALRLCPTH---------ADSLNNLANIKREQGNIEEAVRLYRK 342
Query: 562 ALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIA 621
AL ++ + S++A + Q G + L +Y E+ + S A
Sbjct: 343 ALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI---------------RISPTFADA 387
Query: 622 LNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAI 681
+ MG ++ A + + A I +P +SNLA + G + EAI
Sbjct: 388 YSNMGNTLKEMQDVQGALQCYTRAIQI--------NPAFADAHSNLASIHKDSGNIPEAI 439
Score = 32.7 bits (73), Expect = 3.6
Identities = 51/259 (19%), Positives = 93/259 (35%), Gaps = 46/259 (17%)
Query: 481 FKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLT 540
F T + +P + + L +++ G+++E+ + ALR+ + G
Sbjct: 67 FSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL---------KPDFIDGYI 117
Query: 541 NVSAIYESMNELEKALKLLQKALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTL 600
N++A + ++E A++ AL D +S + + +G + Y ++ T
Sbjct: 118 NLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 177
Query: 601 KNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATEL--------------FEEAK 646
N S +G N G + ++ F +A L +EA+
Sbjct: 178 PNFAVAW--------SNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEAR 229
Query: 647 SILEHEYGPY------HPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANP 700
I + Y P V+ NLA Y G +D AI + ++ P
Sbjct: 230 -IFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------P 280
Query: 701 DVDDEKRRLSELLKEAGRV 719
D L+ LKE G V
Sbjct: 281 HFPDAYCNLANALKEKGSV 299
>OGT1_HUMAN (O15294) UDP-N-acetylglucosamine--peptide
N-acetylglucosaminyltransferase 110 kDa subunit (EC
2.4.1.-) (O-GlcNAc transferase p110 subunit)
Length = 1036
Score = 48.1 bits (113), Expect = 8e-05
Identities = 88/420 (20%), Positives = 157/420 (36%), Gaps = 86/420 (20%)
Query: 307 LERSIEIPVIGESQQHALAKFAGHMQLGDTYAMLGQLENSIMCYSSGFEVQRQVLGETDP 366
L+RS + Q LA+ + LG+ Y GQL+ +I Y ++ + D
Sbjct: 61 LDRSAHFSTLAIKQNPLLAE--AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI---DG 115
Query: 367 RVGETCRYVA--------EANVQALQFDEAERLCQMALDIHKANSSAPSLEEAADRRLMG 418
+ VA +A V ALQ++ L + D+ + LEEA L
Sbjct: 116 YINLAAALVAAGDMEGAVQAYVSALQYNPD--LYCVRSDLGNLLKALGRLEEAKACYLKA 173
Query: 419 LILDTKGNHEAALEHLVLASMAM----VANGQEVEVASVDCSIGDTYLSMSR-------Y 467
+ +T+ N A +L A +A + ++D + D Y+++ +
Sbjct: 174 I--ETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 231
Query: 468 DEAVFAYEKALTV---------------FKTG-----------KGENHPAVGSVFVRLAD 501
D AV AY +AL++ ++ G E P + LA+
Sbjct: 232 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLAN 291
Query: 502 LHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQK 561
G + E++ ++ALR+ A L N++ I +E+A++L +K
Sbjct: 292 ALKEKGSVAEAEDCYNTALRLCPTH---------ADSLNNLANIKREQGNIEEAVRLYRK 342
Query: 562 ALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIA 621
AL ++ + S++A + Q G + L +Y E+ + S A
Sbjct: 343 ALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI---------------RISPTFADA 387
Query: 622 LNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAI 681
+ MG ++ A + + A I +P +SNLA + G + EAI
Sbjct: 388 YSNMGNTLKEMQDVQGALQCYTRAIQI--------NPAFADAHSNLASIHKDSGNIPEAI 439
Score = 32.7 bits (73), Expect = 3.6
Identities = 51/259 (19%), Positives = 93/259 (35%), Gaps = 46/259 (17%)
Query: 481 FKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLT 540
F T + +P + + L +++ G+++E+ + ALR+ + G
Sbjct: 67 FSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL---------KPDFIDGYI 117
Query: 541 NVSAIYESMNELEKALKLLQKALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTL 600
N++A + ++E A++ AL D +S + + +G + Y ++ T
Sbjct: 118 NLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 177
Query: 601 KNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATEL--------------FEEAK 646
N S +G N G + ++ F +A L +EA+
Sbjct: 178 PNFAVAW--------SNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEAR 229
Query: 647 SILEHEYGPY------HPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVREEKLGTANP 700
I + Y P V+ NLA Y G +D AI + ++ P
Sbjct: 230 -IFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------P 280
Query: 701 DVDDEKRRLSELLKEAGRV 719
D L+ LKE G V
Sbjct: 281 HFPDAYCNLANALKEKGSV 299
>OGT_CAEEL (O18158) UDP-N-acetylglucosamine--peptide
N-acetylglucosaminyltransferase (EC 2.4.1.-) (O-GlcNAc)
(OGT)
Length = 1151
Score = 47.8 bits (112), Expect = 1e-04
Identities = 75/352 (21%), Positives = 126/352 (35%), Gaps = 66/352 (18%)
Query: 333 LGDTYAMLGQLENSIMCYSSGFEVQRQVLGETDPRVGETCRYVAEANVQALQFDEAERLC 392
LG+ +G+LE + +CY E Q Q +G E + F++A L
Sbjct: 267 LGNLLKAMGRLEEAKVCYLKAIETQPQ-FAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLD 325
Query: 393 QMALDIHKANSSAPSLEEAADRRLMGLI--LDTKGNHEAALEHLVLASMAMVANGQEVEV 450
LD + + DR + + L+ GNH
Sbjct: 326 PNFLDAYINLGNVLKEARIFDRAVSAYLRALNLSGNH----------------------- 362
Query: 451 ASVDCSIGDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIK 510
A V ++ Y D A+ Y+KA+ + P + LA+ G +
Sbjct: 363 AVVHGNLACVYYEQGLIDLAIDTYKKAIDL--------QPHFPDAYCNLANALKEKGSVV 414
Query: 511 ESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSP 570
E++ AL + N N++ I ++E A +L KAL IY +
Sbjct: 415 EAEQMYMKALELCPTHADSQN---------NLANIKREQGKIEDATRLYLKALEIYPEFA 465
Query: 571 GQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACV 630
S++A I Q G + + +Y E+ ++ A T A S +G L +MG +
Sbjct: 466 AAHSNLASILQQQGKLNDAILHYKEA---IRIAPTFADAY-----SNMGNTLKEMGDSSA 517
Query: 631 QLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEAIQ 682
+ + A ++ +P +SNLA + G + EAIQ
Sbjct: 518 AIACYNRAIQI---------------NPAFADAHSNLASIHKDAGNMAEAIQ 554
Score = 38.5 bits (88), Expect = 0.065
Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 32/182 (17%)
Query: 499 LADLHNRTGKIKESKSYCDSALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKL 558
LA ++G E++ YC+ + N +P L +SAI LEK+++
Sbjct: 131 LAHRQFQSGNYVEAEKYCNLVFQSDPNNLPT---------LLLLSAINFQTKNLEKSMQY 181
Query: 559 LQKALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFI 618
A+ + N Q Y LGNY + L++A+ + + K FI
Sbjct: 182 SMLAIKVNN--------------QCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFI 227
Query: 619 GIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLD 678
+N + A V +A + A I +P+ V S+L A+GRL+
Sbjct: 228 DAYIN-LAAALVSGGDLEQAVTAYFNALQI--------NPDLYCVRSDLGNLLKAMGRLE 278
Query: 679 EA 680
EA
Sbjct: 279 EA 280
>TTCJ_HUMAN (Q6DKK2) Tetratricopeptide repeat protein 19 (TPR repeat
protein 19)
Length = 380
Score = 47.4 bits (111), Expect = 1e-04
Identities = 48/195 (24%), Positives = 83/195 (41%), Gaps = 24/195 (12%)
Query: 556 LKLLQKALLIYNDSPGQQSSIAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKS 615
+++ K IY Q+ ++AG E + + E K + ++ EK +
Sbjct: 179 IEISLKLASIYAAQNRQEFAVAGYE-------FCISTLEEKIEREKELAEDIMSVEEKAN 231
Query: 616 S--FIGIALNQMGLACVQLYAFG----EATELFEEAKSILEHEYGPYHPETLGVYSNLAG 669
+ +G+ L+ AC + F +A ++E+A I E G HP+T+ + S+LA
Sbjct: 232 THLLLGMCLD----ACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLAT 287
Query: 670 TYDAIGRLDEAIQILEYVVSVREEKLGTA--NPDVDDEKRRLSELLKEAGRVRSRKVMSL 727
T DA GR DEA Y+ R L +P++ L+ +L R K +
Sbjct: 288 TLDAQGRFDEA-----YIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQ 342
Query: 728 ENLLDANARIPNINL 742
E L A + I++
Sbjct: 343 EALKQAKLKKDEISV 357
Score = 35.4 bits (80), Expect = 0.55
Identities = 28/104 (26%), Positives = 48/104 (45%), Gaps = 5/104 (4%)
Query: 461 YLSMSRY-DEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSA 519
YL S+ +A YEKAL + + +GE HP + LA + G+ E+ Y A
Sbjct: 246 YLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRA 305
Query: 520 LRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKAL 563
+ +N E+ L+N++A+ +A ++ Q+AL
Sbjct: 306 SDLARQ----INHPELHMVLSNLAAVLMHRERYTQAKEIYQEAL 345
>IF3X_DICDI (O15818) Putative eukaryotic translation initiation factor
3 subunit (eIF-3)
Length = 1321
Score = 45.8 bits (107), Expect = 4e-04
Identities = 44/221 (19%), Positives = 88/221 (38%), Gaps = 5/221 (2%)
Query: 458 GDTYLSMSRYDEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCD 517
G T+ + +Y+ A +AL ++ G HP G+ F LA L + + + Y
Sbjct: 963 GKTFFNQRKYELATELLGEALAIYHQVHGPIHPDAGACFTHLAMLAYQNEQYDLAIEYQK 1022
Query: 518 SALRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQS-SI 576
+AL I E G++ E T ++ + +++ ++ L + + G+ +
Sbjct: 1023 NALVITEK-TAGLDHHETVQAYTTLAVFCQRSGRYNESIGYMKHVLYLTDLLGGEYNPER 1081
Query: 577 AGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFG 636
A I + + + + LK + + ++M + C + F
Sbjct: 1082 ASIYTAIAAILEDTERFDLALEFLKQTLKHQEFLFTPDHLMCSTTYHKMAIVCARATNFD 1141
Query: 637 EATELFEEAKSILEHEYGPYHPET---LGVYSNLAGTYDAI 674
++ +++ ILE E G HP T L Y+ L+ T + I
Sbjct: 1142 DSIIHQKKSTDILEKELGEAHPRTKQSLEFYTGLSQTANQI 1182
Score = 36.6 bits (83), Expect = 0.25
Identities = 40/172 (23%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 530 VNPEEIAS-GLTNVSAIYESMNELEKALKLLQKALLIYNDSPGQQSSIAGI-EAQMGVMY 587
VNP L + + + E A +LL +AL IY+ G AG + ++
Sbjct: 949 VNPRSTDGLDLLEAGKTFFNQRKYELATELLGEALAIYHQVHGPIHPDAGACFTHLAMLA 1008
Query: 588 YMLGNYTESYNTLKNAITKLRAIGEKKSSFIGIALNQMGLACVQLYAFGEATELFEEAKS 647
Y Y + KNA+ I EK + G+ ++ A L F + + + E+
Sbjct: 1009 YQNEQYDLAIEYQKNALV----ITEKTA---GLDHHETVQAYTTLAVFCQRSGRYNESIG 1061
Query: 648 ILEHEY-------GPYHPETLGVYSNLAGTYDAIGRLDEAIQILEYVVSVRE 692
++H G Y+PE +Y+ +A + R D A++ L+ + +E
Sbjct: 1062 YMKHVLYLTDLLGGEYNPERASIYTAIAAILEDTERFDLALEFLKQTLKHQE 1113
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/100 (24%), Positives = 44/100 (44%)
Query: 619 GIALNQMGLACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLD 678
G+ L + G + ATEL EA +I +GP HP+ +++LA + D
Sbjct: 956 GLDLLEAGKTFFNQRKYELATELLGEALAIYHQVHGPIHPDAGACFTHLAMLAYQNEQYD 1015
Query: 679 EAIQILEYVVSVREEKLGTANPDVDDEKRRLSELLKEAGR 718
AI+ + + + E+ G + + L+ + +GR
Sbjct: 1016 LAIEYQKNALVITEKTAGLDHHETVQAYTTLAVFCQRSGR 1055
>NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Fragment)
Length = 810
Score = 43.5 bits (101), Expect = 0.002
Identities = 56/263 (21%), Positives = 94/263 (35%), Gaps = 29/263 (11%)
Query: 5 VTNGVCDGAVNEMNGNHSPSKETLAPVKSPRGSLSPQRGQNGGPNFPVDGVIEPSIEQLY 64
V V + E +E +A KSP + +P+ + G +G E E+
Sbjct: 369 VKEEVKEEEAEEKEEKEEAEEEVVAAKKSPVKATAPELKEEEGEKEEEEGQEE---EEEE 425
Query: 65 ENVCDMQSSDQSPSRKSFGSDGDESRIDSELRQLVGGR-------MREVEIMEEEVE--- 114
E +++ S K S+ +E + E G +E + MEE+ E
Sbjct: 426 EEAAKSDQAEEGGSEKEGSSEKEEGEQEEEGETEAEGEGEEAAAEAKEEKKMEEKAEEVA 485
Query: 115 ------VEVEKERGGSSSGEISSGVGGLSSNEKKLD-KVHEIQSATTSSVS--------- 158
E + E+ + ++ S K + K E +S T S +
Sbjct: 486 PKEELAAEAKVEKPEKAKSPVAKSPTTKSPTAKSPEAKSPEAKSPTAKSPTAKSPVAKSP 545
Query: 159 TEKSVKALNSQLDASPKSKPKGKSPPAKAPLERKNDKPLLRKQTKGVASGVKSLKSSPLG 218
T KS +A + + + P KSP AK+P + + + K G G + K
Sbjct: 546 TAKSPEAKSPEAKSPTAKSPTAKSPAAKSPAPKSPVEEVKPKAEAGAEKGEQKEKVEEEK 605
Query: 219 KSVSLNRVENSAESALDKPERAP 241
K + E AE +KP+ P
Sbjct: 606 KEAKESPKEEKAEKKEEKPKDVP 628
>TTCJ_MOUSE (Q8CC21) Tetratricopeptide repeat protein 19 (TPR repeat
protein 19)
Length = 365
Score = 42.4 bits (98), Expect = 0.005
Identities = 29/113 (25%), Positives = 50/113 (43%), Gaps = 8/113 (7%)
Query: 576 IAGIEAQMGVMYYMLGNYTESYNTLKNAITKLRAIGEKKSS--------FIGIALNQMGL 627
+A I A + L Y +TL+ I + + + E S +G+ L+
Sbjct: 176 LANIYAAQNKQEFALAGYEFCISTLEGKIEREKELAEDIMSEETANTYLLLGMCLDSCAR 235
Query: 628 ACVQLYAFGEATELFEEAKSILEHEYGPYHPETLGVYSNLAGTYDAIGRLDEA 680
+ +A ++E+A I + G HP+T+ + S+LA T DA G D+A
Sbjct: 236 YLLFSKQLSQAQRMYEKALQICQEIQGERHPQTIVLMSDLATTLDAQGHFDDA 288
Score = 33.1 bits (74), Expect = 2.7
Identities = 28/104 (26%), Positives = 47/104 (44%), Gaps = 5/104 (4%)
Query: 461 YLSMSRY-DEAVFAYEKALTVFKTGKGENHPAVGSVFVRLADLHNRTGKIKESKSYCDSA 519
YL S+ +A YEKAL + + +GE HP + LA + G ++ Y A
Sbjct: 236 YLLFSKQLSQAQRMYEKALQICQEIQGERHPQTIVLMSDLATTLDAQGHFDDAYIYMQRA 295
Query: 520 LRIYENPMPGVNPEEIASGLTNVSAIYESMNELEKALKLLQKAL 563
+ +N E+ L+N++AI +A ++ Q+AL
Sbjct: 296 SDLARE----INHPELHMVLSNLAAILIHRERYTQAKEIYQEAL 335
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.311 0.130 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,483,122
Number of Sequences: 164201
Number of extensions: 3572778
Number of successful extensions: 11814
Number of sequences better than 10.0: 226
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 186
Number of HSP's that attempted gapping in prelim test: 11300
Number of HSP's gapped (non-prelim): 540
length of query: 746
length of database: 59,974,054
effective HSP length: 118
effective length of query: 628
effective length of database: 40,598,336
effective search space: 25495755008
effective search space used: 25495755008
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Lotus: description of TM0166.9