BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0148.5
(586 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SLP1_CLOTM (Q06852) Cell surface glycoprotein 1 precursor (Outer... 80 1e-14
NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa neur... 61 9e-09
PCLO_RAT (Q9JKS6) Piccolo protein (Multidomain presynaptic cytom... 59 4e-08
ZAN_HUMAN (Q9Y493) Zonadhesin precursor 58 6e-08
IGA4_HAEIN (P45386) Immunoglobulin A1 protease precursor (EC 3.4... 57 1e-07
TRDN_RABIT (Q28820) Triadin 57 2e-07
SSP2_PLAYO (Q01443) Sporozoite surface protein 2 precursor 55 5e-07
DD21_MOUSE (Q9JIK5) Nucleolar RNA helicase II (Nucleolar RNA hel... 52 3e-06
PCLO_MOUSE (Q9QYX7) Piccolo protein (Presynaptic cytomatrix prot... 52 4e-06
NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 k... 52 6e-06
NFM_CHICK (P16053) Neurofilament triplet M protein (160 kDa neur... 52 6e-06
UN89_CAEEL (O01761) Muscle M-line assembly protein unc-89 (Uncoo... 51 7e-06
HRX_MOUSE (P55200) Zinc finger protein HRX (ALL-1) (Fragment) 51 7e-06
SPKC_SYNY3 (P74745) Serine/threonine-protein kinase C (EC 2.7.1.37) 50 2e-05
IF2_BORPE (Q7VYR2) Translation initiation factor IF-2 50 2e-05
IF2_BORPA (Q7W9A5) Translation initiation factor IF-2 50 2e-05
HS1_HUMAN (P14317) Hematopoietic lineage cell specific protein (... 49 4e-05
Y046_UREPA (Q9PR99) Hypothetical protein UU046 48 6e-05
RRP1_DROME (P27864) Recombination repair protein 1 (DNA-(apurini... 48 6e-05
YKF4_YEAST (P35732) Hypothetical 84.0 kDa protein in NUP120-CSE4... 48 8e-05
>SLP1_CLOTM (Q06852) Cell surface glycoprotein 1 precursor (Outer
layer protein B) (S-layer protein 1)
Length = 1664
Score = 80.5 bits (197), Expect = 1e-14
Identities = 112/477 (23%), Positives = 171/477 (35%), Gaps = 64/477 (13%)
Query: 59 VLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPE 118
V+ P P+ A+ PI +TP ++ E P P P + EP P
Sbjct: 759 VIQPAPIKAASDEPIPTDTPSDEPTPSDE-----PTPSDEPTPSD----------EPTPS 803
Query: 119 PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKP 178
EP P ET + PT S + + S+E ++ P P P
Sbjct: 804 DEPTPSETP--EEPIPTDTPSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETP 855
Query: 179 KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEK 238
+EP T+ P P P P ++ EP S+ P PE P+ P D E
Sbjct: 856 EEPIPTDTPSDEPTPS---DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EP 911
Query: 239 NKGENLTPTDE-NELDRRNRREELVALVTSDEKIVN--PRDHLVPL-KSIPGFVLEQQTQ 294
+ TP+DE D +E T +E I P D P + P +
Sbjct: 912 TPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDE 971
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN-TEPPETK 353
P P P+ T P E+ I + + + D+ ++ P
Sbjct: 972 PTPSDEPTPSDEPTPSDEPT-PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1030
Query: 354 KRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKN 413
+EP + P ++ IP+D+ PT + TP
Sbjct: 1031 DEPTPSDEPTPSDEPTPSETP-------EEPIPTDTPSDEPTPSDEPTPS---------- 1073
Query: 414 VLLSEGGKSNEH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMS 471
E S+E + +PT + + P + PS +PT P+D+P P D TP E S
Sbjct: 1074 ---DEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPS-DEPTPS 1128
Query: 472 NAQRNNVLLSEGVKSNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATPKHS 527
+ + E + PT+TP + + PS +PT P+D+P P D TP +
Sbjct: 1129 DEPTPSETPEEPI-----PTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTPSET 1179
Score = 79.0 bits (193), Expect = 3e-14
Identities = 114/520 (21%), Positives = 170/520 (31%), Gaps = 68/520 (13%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKI-KEEGIESHEHDQVLLPEPVVVATAIPITLE 76
E EP+P+ E + S + + +E S E PE PI +
Sbjct: 896 ETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEE-------PIPTD 948
Query: 77 TPKEQGAEPIEATVV-HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPT 135
TP ++ E T P P P + E +P P P+E TD
Sbjct: 949 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDE 1008
Query: 136 QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPL 195
S + + S+E ++ P P P+EP T+ P P P
Sbjct: 1009 PTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPS- 1067
Query: 196 GLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-NELDR 254
P ++ EP S+ P PE P+ P D E + TP+DE D
Sbjct: 1068 --DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPTPSDE 1124
Query: 255 RNRREELVALVTSDEKIVN--PRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQS 312
+E T +E I P D P +P P P+
Sbjct: 1125 PTPSDEPTPSETPEEPIPTDTPSDEPTP-----------SDEPTPSDEPTPSDEPTPSDE 1173
Query: 313 QTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPET 372
T P E+ I P ++ P +EP + P
Sbjct: 1174 PT-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPSDEPTPSDEPTPSD 1215
Query: 373 LMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEH--NGQPT 430
S ++ IP+D+ PT + TP E S+E + +PT
Sbjct: 1216 EPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEPTPSDEPTPSDEPT 1261
Query: 431 ETPVQKSVSPINAPSIDPT-----LPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVK 485
+ + P + PS +PT P+D+P P D TP ++
Sbjct: 1262 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETP 1321
Query: 486 SNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATP 524
PT+TP + + PS +PT P+D+P P D TP
Sbjct: 1322 EEPIPTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTP 1360
Score = 79.0 bits (193), Expect = 3e-14
Identities = 119/528 (22%), Positives = 170/528 (31%), Gaps = 77/528 (14%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP--------EPVVVATAIPI 73
EP PS E + + EE I + P EP P
Sbjct: 830 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 889
Query: 74 TLETPKEQGAEPIEATVV--HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
TP E EPI P P P + E +P P P+E TD
Sbjct: 890 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDT 949
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
S + + S+E ++ P P P+EP T+ P P
Sbjct: 950 PSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1009
Query: 192 EP---------PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGE 242
P P P ++ EP S+ P PE P+ P D E +
Sbjct: 1010 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSD 1068
Query: 243 NLTPTDE-NELDRRNRREELVALVTSDEKIVN--PRDHLVPLKSIPGFVLEQQTQPGPVI 299
TP+DE D +E T +E I P D P +P P
Sbjct: 1069 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTP-----------SDEPTPSD 1117
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDR 359
P+ T P E+ I P ++ P
Sbjct: 1118 EPTPSDEPTPSDEPT-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPS 1159
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEG 419
+EP + P S ++ IP+D+ PT + TP E
Sbjct: 1160 DEPTPSDEPTPSDEPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEP 1205
Query: 420 GKSNEH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNN 477
S+E + +PT + + P + PS +PT P+D+P P D TP E S+ +
Sbjct: 1206 TPSDEPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPS-DEPTPSDEPTPS 1263
Query: 478 VLLSEGVKSNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATP 524
E + PT+TP + + PS +PT P+D+P P D TP
Sbjct: 1264 ETPEEPI-----PTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTP 1305
Score = 76.3 bits (186), Expect = 2e-13
Identities = 117/527 (22%), Positives = 170/527 (32%), Gaps = 69/527 (13%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP--------EPVVVATAIPI 73
EP PS E + + EE I + P EP P
Sbjct: 787 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 846
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
TP E EPI P P + E +P P EP + +
Sbjct: 847 DEPTPSETPEEPIPTDT----PSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPI 902
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEP 193
PT S + + S+E ++ P P P+EP T+ P P P
Sbjct: 903 PTDTPSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETPEEPIPTDTPSDEPTP 956
Query: 194 ---------PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENL 244
P P ++ EP S+ P PE P+ P D E +
Sbjct: 957 SDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEP 1015
Query: 245 TPTDE-NELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCP 303
TP+DE D +E SDE P D P +T P+ P
Sbjct: 1016 TPSDEPTPSDEPTPSDEPTP---SDEP--TPSDEPTP----------SETPEEPIPTDTP 1060
Query: 304 NSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPN 363
+ T T S +P ++ P +EP
Sbjct: 1061 SDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPT 1120
Query: 364 KCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSN 423
+ P S ++ IP+D+ PT + TP E S+
Sbjct: 1121 PSDEPTPSDEPTPSETP-EEPIPTDTPSDEPTPSDEPTPS-------------DEPTPSD 1166
Query: 424 EH--NGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLS 481
E + +PT + + P + PS +PT P+D+P P D TP E S+ +
Sbjct: 1167 EPTPSDEPTPSETPEEPIPTDTPSDEPT-PSDEPTPSDEPTPS-DEPTPSDEPTPSETPE 1224
Query: 482 EGVKSNEQPTETPVQKSV-NPIKAPSIDPTLPTDQPVPIDLATPKHS 527
E + PT+TP + + PS +PT P+D+P P D TP +
Sbjct: 1225 EPI-----PTDTPSDEPTPSDEPTPSDEPT-PSDEPTPSDEPTPSET 1265
Score = 64.3 bits (155), Expect = 8e-10
Identities = 108/506 (21%), Positives = 157/506 (30%), Gaps = 52/506 (10%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP----EPVVVATAIPI 73
E P P+P + E+ + +E S E P EP P
Sbjct: 928 EPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPS 987
Query: 74 TLETPKEQGAEPIEATVV--HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDH 131
TP E EPI P P P + E +P P EP +
Sbjct: 988 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 1047
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCP 191
SE + + S+E ++ P P P+EP T+ P P
Sbjct: 1048 SETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1107
Query: 192 EPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-N 250
P P ++ EP S+ P PE P+ P D E + TP+DE
Sbjct: 1108 TPS---DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPT 1163
Query: 251 ELDRRNRREELVALVTSDEKIVN--PRDHLVPL-KSIPGFVLEQQTQPGPVIPVCPNSAS 307
D +E T +E I P D P + P +P P P+
Sbjct: 1164 PSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETP 1223
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPP-ETKKRVLDREEPNKCN 366
+ IP + + + P + P ET + + + P+
Sbjct: 1224 ----EEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEP 1279
Query: 367 AKLPETLMLASNCHIDQAIPSDS-NPA-VPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNE 424
E D+ PSD P+ PT + TP + + + E S+E
Sbjct: 1280 TPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDE 1339
Query: 425 HNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGV 484
TP + PS +PT P+D+P P D TP
Sbjct: 1340 PTPSDEPTPSDEPT-----PSDEPT-PSDEPTPSDEPTPS-------------------- 1373
Query: 485 KSNEQPTETPVQKSVNPIKAPSIDPT 510
++ E+PT T P PS PT
Sbjct: 1374 ETPEEPTPT-----TTPTPTPSTTPT 1394
Score = 58.9 bits (141), Expect = 4e-08
Identities = 95/452 (21%), Positives = 131/452 (28%), Gaps = 51/452 (11%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPKEQ 81
EP PS E + + EE I + P + P + P
Sbjct: 1026 EPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1085
Query: 82 GAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP----EPKETSNTDHSEPTQL 137
T P+P P+ + EP P EP EP + + PT
Sbjct: 1086 DEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDT 1145
Query: 138 CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGL 197
S + + S+E ++ P P P+EP T+ P P P
Sbjct: 1146 PSDEPTPSDEPTPSDEPTP------SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPS--- 1196
Query: 198 AIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE-NELDRRN 256
P ++ EP S+ P PE P+ P D E + TP+DE D
Sbjct: 1197 DEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSD-EPTPSDEPTPSDEPTPSDEPT 1255
Query: 257 RREELVALVTSDEKIV--NPRDHLVPL-KSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQ 313
+E T +E I P D P + P +P P P+
Sbjct: 1256 PSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEP 1315
Query: 314 TIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETL 373
T P E+ I P ++ P +EP + P
Sbjct: 1316 T-PSETPEEPI-----------------PTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDE 1357
Query: 374 MLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNG------ 427
S D+ PSD P PE TP GG G
Sbjct: 1358 PTPS----DEPTPSD-EPTPSETPEEPTPTTTPTPTPSTTPTSGSGGSGGSGGGGGGGGG 1412
Query: 428 ----QPTETPVQKSVSPINAPSIDPTLPTDQP 455
PT TP K S I+ P+D P
Sbjct: 1413 TVPTSPTPTPTSKPTSTPAPTEIEEPTPSDVP 1444
Score = 31.6 bits (70), Expect = 6.0
Identities = 18/44 (40%), Positives = 28/44 (62%), Gaps = 7/44 (15%)
Query: 479 LLSEGVKSNEQPTETPVQKSVNPIKAPSIDPT-LPTDQPVPIDL 521
+++EG + E+PTE PV P + P +DPT T++PVP +L
Sbjct: 365 IVAEGEEPGEEPTEEPV-----PTETP-VDPTPTVTEEPVPSEL 402
>NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1026
Score = 60.8 bits (146), Expect = 9e-09
Identities = 108/517 (20%), Positives = 177/517 (33%), Gaps = 35/517 (6%)
Query: 72 PITLETPKEQGAEPIEATVVH-PVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTD 130
PI P +G I + H V + K K +K+ ++E Q E +E + +
Sbjct: 417 PIPFSLP--EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEE 474
Query: 131 HSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTE--HPR 188
E + ++ K+ +G E EA E T+ P + PE + K P E P
Sbjct: 475 EKEAKE----EEGKEEEGGEEEEA--EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA 528
Query: 189 VCPEPPLGLA-IPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPT 247
P A P + + K P + A+ P P A K+ + +P
Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588
Query: 248 DENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSAS 307
E + A E+ +P + P+K E ++ P + S
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 308 LIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNA 367
E++ K +K K P+K + K + P K A
Sbjct: 649 PEKAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 708
Query: 368 KLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNG 427
K PE + + + S P E KTP+K K K++ + +
Sbjct: 709 KSPE----KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 764
Query: 428 QPTETPVQKSVSPINAPSIDPTLP--TDQPVPIDLATPKHSEGKM---SNAQRNNVLLSE 482
++P K+ + A S P PV ++ +P+ ++ + + A + E
Sbjct: 765 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 824
Query: 483 GVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKR 542
VKS + E P + V K P P ++ P ATPK E K SK + K
Sbjct: 825 EVKSPVKEEEKPQEVKV---KEP---PKKAEEEKAP---ATPKTEEKKDSKKEEAPK--- 872
Query: 543 ALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVK 579
K A V + + P + K EA+ K
Sbjct: 873 --KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 907
Score = 52.0 bits (123), Expect = 4e-06
Identities = 89/443 (20%), Positives = 155/443 (34%), Gaps = 69/443 (15%)
Query: 12 SKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI 71
+K + PE SP +++ +S K K +K K S E ++ PE
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAK-------SPEKEEAKSPEKA----KS 674
Query: 72 PITLETPK-EQGAEPIEATVVHPVPDQRPAKTHRK--KKKKETVLEPQPEPE----PEPK 124
P+ E E+ P++A P + P K K +K K V E PE P +
Sbjct: 675 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 734
Query: 125 ETSNTDHSEPTQLCSVKKKKKRKGAESNEAV----AELATVCTEPPAVQGGVLPEPKPKE 180
E + ++ K +K K E + + E T E PE K K
Sbjct: 735 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE-KAKS 793
Query: 181 PCSTEHPRVCPEPPLGLAIPIDPEKNRKEAE-PNESNAEHPRACPEPPLGLAIPIDPEKN 239
P E + P P+ + E E P + + P E P + + P+K
Sbjct: 794 PVKEE-----VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 848
Query: 240 KGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVI 299
+ E T + E + +++EE P K P +E++ +P
Sbjct: 849 EEEKAPATPKTEEKKDSKKEE------------------APKKEAPKPKVEEKKEPA--- 887
Query: 300 PVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDR 359
+ + + V +++ + ++ +++ + K + +P E K + +
Sbjct: 888 ---------VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE--KTEVAK 936
Query: 360 EEPNKCNAKLPETLMLASNCHIDQAIP--SDSNPAVPTNPEHKTPKKWKKRAKKKNVLLS 417
+EP+ AK P + +A P D+ PE K PK K + L
Sbjct: 937 KEPDDAKAKEP-----SKPAEKKEAAPEKKDTKEEKAKKPEEK-PKTEAKAKEDDKTLSK 990
Query: 418 EGGKSNEHNGQPTETPVQKSVSP 440
E K + + + QK P
Sbjct: 991 EPSKPKAEKAEKSSSTDQKDSKP 1013
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/171 (26%), Positives = 74/171 (42%), Gaps = 22/171 (12%)
Query: 12 SKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAI 71
SKK +K P P E+ +E + K K K + KEE D+ +P P A A
Sbjct: 865 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA-----EDKKKVPTPEKEAPA- 918
Query: 72 PITLETPKEQGAEPIEAT-VVHPVPD----QRPAKTHRKKK----KKETVLEPQPEPEPE 122
+ ++ A+P E T V PD + P+K KK+ KK+T E +PE +
Sbjct: 919 ----KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 974
Query: 123 PKETSNTDHSEPT---QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQG 170
PK + + T + K +K K + +++ ++ TE A +G
Sbjct: 975 PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1025
>PCLO_RAT (Q9JKS6) Piccolo protein (Multidomain presynaptic
cytomatrix protein)
Length = 5085
Score = 58.9 bits (141), Expect = 4e-08
Identities = 127/566 (22%), Positives = 201/566 (35%), Gaps = 80/566 (14%)
Query: 19 EKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPE--------------P 64
++P P SP Q S + K ++ G+E Q P+ P
Sbjct: 284 QQPGPAKSPAQPAGTGKSPAQPPAKTPGQQAGLEKTSSSQQPGPKSLAQTPGHGKFPLGP 343
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPV--PDQR--PAKTHRKKKKKETVLEPQPEP- 119
V P T + P +Q A V P P Q+ P KT ++ QP P
Sbjct: 344 VKSPAQQPGTAKHPAQQPGPQTAAKVPGPTKTPAQQSGPGKTPAQQPGPTKPSPQQPIPA 403
Query: 120 EPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPK 179
+P+P++ T ++P Q K + ++ A + P Q +P+P+
Sbjct: 404 KPQPQQPVATK-TQPQQSAPAKPQPQQPAP----AKPQPQQPTPAKPQPQPPTPAKPQPQ 458
Query: 180 EPCSTEHPRVCPEPPL---------GLAIPIDPEKNRKEAEPNESNAEHP---RACPEPP 227
P +T+ P+PP GLA P + + ++ P A P
Sbjct: 459 PPTATKPQ---PQPPTATKPHHQQPGLAKPSAQQPTKSISQTVTGRPLQPPPTSAAQTPA 515
Query: 228 LGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGF 287
GL+ I P N E L E N E + V S NP HL +K
Sbjct: 516 QGLSKTICPLCNTTELLLHIPEKA--NFNTCTECQSTVCSLCGF-NPNPHLTEIKEWLCL 572
Query: 288 VLE-QQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRK---RMNSMPD 343
+ Q+ G + P+S ++ T P T K S+ + K++ + +S
Sbjct: 573 NCQMQRALGGDLAAAIPSSPQPTPKAATAPTA-TASKSPVPSQQASPKKEPPSKQDSPKA 631
Query: 344 KHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCH-----------IDQAIPSDSNPA 392
+ +PPE KK ++ P K P L+ H + +A+P + P
Sbjct: 632 LESKKPPEPKKPPEPKKPPEP---KKPPPLVKQPTLHGPTPATAPQLPVAEALPEPAPPK 688
Query: 393 VPTNP------------EHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSP 440
P+ P E K PK + RA ++ S K + + Q K+ SP
Sbjct: 689 EPSGPLPEQAKAPVGDVEPKQPKMTETRA---DIQSSSTTKPDILSSQVQSQAQVKTASP 745
Query: 441 INAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTE--TPVQKS 498
+ S P+ P + TP S+ A + ++ G S + + P+QK
Sbjct: 746 LKTDSAKPS--QSFPPTGEKTTPLDSKAMPRPASDSKIISQPGPGSESKDPKHIDPIQKK 803
Query: 499 VNPIKAPSIDPTLPTDQPVPIDLATP 524
P KA P +PVP TP
Sbjct: 804 DEPKKAQPKGSPKPETKPVPKGSPTP 829
Score = 46.2 bits (108), Expect = 2e-04
Identities = 65/306 (21%), Positives = 109/306 (35%), Gaps = 32/306 (10%)
Query: 67 VATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKET 126
+A AIP + + + P PVP Q+ + K+++ + + PEPK+
Sbjct: 584 LAAAIPSSPQPTPKAATAPTATASKSPVPSQQASPKKEPPSKQDSPKALESKKPPEPKKP 643
Query: 127 SNTDH-SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTE 185
EP + + K+ G T T P LPEP P + S
Sbjct: 644 PEPKKPPEPKKPPPLVKQPTLHG----------PTPATAPQLPVAEALPEPAPPKEPSGP 693
Query: 186 HPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHP-----RACPEPPLGLAIPIDPEKNK 240
P + P+G P P+ A+ S+ P + + + A P+ + K
Sbjct: 694 LPEQA-KAPVGDVEPKQPKMTETRADIQSSSTTKPDILSSQVQSQAQVKTASPLKTDSAK 752
Query: 241 --------GENLTPTDENELDRRNRREELVA-----LVTSDEKIVNP-RDHLVPLKSIPG 286
GE TP D + R ++++ + D K ++P + P K+ P
Sbjct: 753 PSQSFPPTGEKTTPLDSKAMPRPASDSKIISQPGPGSESKDPKHIDPIQKKDEPKKAQPK 812
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHN 346
+ +T+P P P S + Q P K ++SR + + P
Sbjct: 813 GSPKPETKPVPKGSPTP-SGTRPTAGQAAPPSQQPPKPQEQSRRFSLNLGGITDAPKSQP 871
Query: 347 TEPPET 352
T P ET
Sbjct: 872 TTPQET 877
Score = 39.7 bits (91), Expect = 0.022
Identities = 108/540 (20%), Positives = 181/540 (33%), Gaps = 108/540 (20%)
Query: 99 PAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPT--QLCSVKKKKKRKGAESNEAVA 156
P + + KK + P+PE +P PK + + PT Q ++ + +S
Sbjct: 799 PIQKKDEPKKAQPKGSPKPETKPVPKGSPTPSGTRPTAGQAAPPSQQPPKPQEQSRRFSL 858
Query: 157 ELATVCTEPPAVQGGVLPEPK--PKEPCSTEHPRVC---------------------PEP 193
L GG+ PK P P T ++ P P
Sbjct: 859 NL-----------GGITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQQGPHP 907
Query: 194 PLGLAIPID----PEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDE 249
G A P P ++ P +S + P P P A+ + + ENL E
Sbjct: 908 QTGPAAPSKQAPTPSQSPAAQGPAKSTGQLP---PAPAKATAVKKEAKAAAAENLESKPE 964
Query: 250 NELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLI 309
+ ++ K+ P P K++P ++ T+P P P+C +L
Sbjct: 965 QAPTAKKTEKDKKP---PPAKVGKPPPS-EPEKAVPAHKPDKTTKPKPACPLCRTELNLG 1020
Query: 310 GQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKL 369
Q TE K N+ + P H TE E L+ + + +L
Sbjct: 1021 SQEPPNFNTCTECK-NQVCNLCGFN-------PTPHLTEIQEWL--CLNCQTQRAISGQL 1070
Query: 370 PETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNV--------------- 414
+ + +A P + PA P++ KTP + + KKK
Sbjct: 1071 GDMGKMPPAPSGPKASPMPA-PAEPSS--QKTPTGTQVKGKKKEAEGKTEAEKPVPEKET 1127
Query: 415 --------LLSEGGKSNEHNGQPTET---PVQKSVSPINAPSID-----------PTLPT 452
+++ K E G+ ++ P +K A S D P L
Sbjct: 1128 ASIEKTPPMVTTDQKLEESEGKKSKVSALPEKKPSEEEKAISADKKERKPPAEEKPPLEE 1187
Query: 453 DQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVK-SNEQPTETPVQKSVNPIKAPSIDP-T 510
+P+P+D P ++ S + + +L V+ E+PT K+ + P P
Sbjct: 1188 KKPIPVDKKLPPEAKPLSSEGEEKHEILKAHVQIPEEEPTGKVAAKAGEEEQQPDSRPEA 1247
Query: 511 LPTDQPVPIDLATPK-------HSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTP 563
LP P+ + A K +EG Q + ++ K + SS Q K+P
Sbjct: 1248 LPGATPLTLPKAGEKERAVAQPQAEGSSKDGQGERSKEKTEKE--EDKSDTSSSQQPKSP 1305
Score = 38.1 bits (87), Expect = 0.064
Identities = 45/184 (24%), Positives = 77/184 (41%), Gaps = 15/184 (8%)
Query: 78 PKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQL 137
P A P+ A P + P T K KKKE + + E KET++ + + P +
Sbjct: 1080 PSGPKASPMPAPA-EPSSQKTPTGTQVKGKKKEAEGKTEAEKPVPEKETASIEKT-PPMV 1137
Query: 138 CSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGL 197
+ +K ++ +G +S + A +P + + + K ++P + E P + + P
Sbjct: 1138 TTDQKLEESEGKKSKVS----ALPEKKPSEEEKAISADKKERKPPAEEKPPLEEKKP--- 1190
Query: 198 AIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNR 257
IP+D +K EA+P S E L + I E+ G+ E E +R
Sbjct: 1191 -IPVD-KKLPPEAKPLSSEGEEKHEI----LKAHVQIPEEEPTGKVAAKAGEEEQQPDSR 1244
Query: 258 REEL 261
E L
Sbjct: 1245 PEAL 1248
Score = 37.4 bits (85), Expect = 0.11
Identities = 79/346 (22%), Positives = 125/346 (35%), Gaps = 44/346 (12%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHE--HDQVLLPE 63
+ + + + K+ R+ E P E+ + KK + K + EG E HE V +PE
Sbjct: 1164 EEKAISADKKERKPPAEEKPPLEEKKPIPVDKKLPPEAKPLSSEGEEKHEILKAHVQIPE 1223
Query: 64 PVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPE----- 118
E ++ + P +P P + +K+ V +PQ E
Sbjct: 1224 EEPTGKVAAKAGEEEQQPDSRP------EALPGATPLTLPKAGEKERAVAQPQAEGSSKD 1277
Query: 119 ------PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGV 172
E KE +D S Q S + G S+ L + + P+ + +
Sbjct: 1278 GQGERSKEKTEKEEDKSDTSSSQQPKS-PQGLSDTGYSSDGISGSLGEIPSLIPSDEKDL 1336
Query: 173 LPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAI 232
L K K+ S E P P LA + EA+ + E +P
Sbjct: 1337 LKGLK-KDSFSQES---SPSSPSDLAKLESTVLSILEAQASTLVGEKAEKKTQPQ----- 1387
Query: 233 PIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFV--LE 290
I PEK + + T T LD EE + S EK V+P+ S GF E
Sbjct: 1388 KISPEKPQDQQKTQTASETLDITISEEE---IKESQEKKVSPKK-----DSEQGFPSRKE 1439
Query: 291 QQTQPGPVIPVCPNSASL-----IGQSQTIPVVDTEQKINKRSRMS 331
+ +P V + P AS +S+ PVV +++ + S S
Sbjct: 1440 HKEKPELVDDLSPRRASYDSVEDSSESENSPVVRRKRRTSIGSSSS 1485
Score = 36.6 bits (83), Expect = 0.19
Identities = 35/147 (23%), Positives = 54/147 (35%), Gaps = 12/147 (8%)
Query: 429 PTETPVQKS---VSPINAPSIDPTLPTDQ------PVPIDLATPKHSEGKMSNAQRNNVL 479
PT+TP Q+S +P P PT P+ Q P P K + + A+
Sbjct: 372 PTKTPAQQSGPGKTPAQQPG--PTKPSPQQPIPAKPQPQQPVATKTQPQQSAPAKPQPQQ 429
Query: 480 LSEGVKSNEQPTET-PVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRK 538
+ +QPT P + P K PT QP P P H + ++K ++
Sbjct: 430 PAPAKPQPQQPTPAKPQPQPPTPAKPQPQPPTATKPQPQPPTATKPHHQQPGLAKPSAQQ 489
Query: 539 KNKRALKSAWSESVHHSSDQNAKTPVQ 565
K ++ + A+TP Q
Sbjct: 490 PTKSISQTVTGRPLQPPPTSAAQTPAQ 516
>ZAN_HUMAN (Q9Y493) Zonadhesin precursor
Length = 2812
Score = 58.2 bits (139), Expect = 6e-08
Identities = 100/454 (22%), Positives = 176/454 (38%), Gaps = 70/454 (15%)
Query: 87 EATVVHPVPDQRPAKTHRKKK------KKETVLEPQPEPEPE----PKETSNTDHSEPT- 135
E V PV P++T + KK TV +P E PKE +PT
Sbjct: 541 ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
Query: 136 --QLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEP 193
+ ++ +K +E +E T+ TE P + P KP P +E P + E
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTI-----PSEKPTIP--SEKPTISTEK 653
Query: 194 PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELD 253
P +P + EP E + EP + P P + PT++ +
Sbjct: 654 P---TVPTE--------EPTTPTEETTTSMEEPVIPTEKPSIPTEKPS---IPTEKPTIS 699
Query: 254 RRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQ 313
++++++ ++P +P + P E+ T P P P I +
Sbjct: 700 MEE------TIISTEKPTISPEKPTIPTEK-PTIPTEKST-ISPEKPTTPTEKPTIPTEK 751
Query: 314 TIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPE-----TKKRVLDREEPNKCNAK 368
P + E+ + + K ++P + T P E T+K + EEP
Sbjct: 752 --PTISPEKPTTPTEKPTISPEKL--TIPTEKPTIPTEKPTIPTEKPTISTEEP---TTP 804
Query: 369 LPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQ 428
ET + +IP + P +PT + ++ +K + + + S E
Sbjct: 805 TEETTISTEK----PSIPME-KPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
Query: 429 PTETPVQKSVSP--INAPSIDPTLPTDQP-VPIDLATPKHSEGKMSNAQRNNVLLSEGVK 485
PTE P ++SP + P+ T+PT++P +PI+ T +E ++ + +
Sbjct: 860 PTEKP---TISPEKLTIPTEKLTIPTEKPTIPIE-ETTISTEKLTIPTEKPTISPEKPTI 915
Query: 486 SNEQPTETPVQKSVNPIKAPSIDP---TLPTDQP 516
S E+PT P +K P + +I T+PT++P
Sbjct: 916 STEKPT-IPTEKPTIPTEETTISTEKLTIPTEKP 948
Score = 57.8 bits (138), Expect = 8e-08
Identities = 104/492 (21%), Positives = 181/492 (36%), Gaps = 87/492 (17%)
Query: 55 EHDQVLLPEPVVVATAIPITLE---TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKET 111
E+ + +P V +T E PKE+ P E + P++ +K T
Sbjct: 561 ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPT 620
Query: 112 VLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAV--Q 169
+ +P E + + P++ ++ +K E E T E P + +
Sbjct: 621 IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE 680
Query: 170 GGVLPEPKPKEP------------CSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNA 217
+P KP P STE P + PE P I EK E + +
Sbjct: 681 KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKP-----TIPTEKPTIPTEKSTISP 735
Query: 218 EHPRACPEPPLGLAIPID-PEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRD 276
E P E P IP + P + + TPT++ + L EK P +
Sbjct: 736 EKPTTPTEKP---TIPTEKPTISPEKPTTPTEKPTISPEK-------LTIPTEKPTIPTE 785
Query: 277 HLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRK 336
P E+ T P + S+ + T+P +T + + + + +
Sbjct: 786 KPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEE----TTISTE 841
Query: 337 RMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTN 396
++ +K T+K + E+P KL IP++ +PT
Sbjct: 842 KLTIPMEKPTI---STEKPTIPTEKPTISPEKL--------------TIPTE-KLTIPT- 882
Query: 397 PEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSID---PTLPTD 453
+K + + E S E PTE P ++SP P+I PT+PT+
Sbjct: 883 -------------EKPTIPIEETTISTEKLTIPTEKP---TISP-EKPTISTEKPTIPTE 925
Query: 454 QP-VPID---LATPK---HSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPS 506
+P +P + ++T K +E + ++ + + S E+PT P +K P + P+
Sbjct: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT-IPTEKLTIPTEKPT 984
Query: 507 I---DPTLPTDQ 515
I PT+PT++
Sbjct: 985 IPTEKPTIPTEK 996
Score = 36.2 bits (82), Expect = 0.24
Identities = 44/188 (23%), Positives = 67/188 (35%), Gaps = 10/188 (5%)
Query: 19 EKPEPLPSPEQD---QEQSCSKKKRR---KKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
EKP LP+ E +E + S +K +K I E + PE + + T
Sbjct: 820 EKPT-LPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE-- 876
Query: 73 ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHS 132
L P E+ PIE T + P + +K T+ +P E + +
Sbjct: 877 -KLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETT 935
Query: 133 EPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPE 192
T+ ++ +K E E T+ TE P + L P K TE P + E
Sbjct: 936 ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTE 995
Query: 193 PPLGLAIP 200
L P
Sbjct: 996 KLTALRPP 1003
>IGA4_HAEIN (P45386) Immunoglobulin A1 protease precursor (EC
3.4.21.72) (IGA1 protease)
Length = 1849
Score = 57.4 bits (137), Expect = 1e-07
Identities = 104/508 (20%), Positives = 193/508 (37%), Gaps = 68/508 (13%)
Query: 75 LETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEP 134
+ETP A E+ + P+ RPA+T + +ET E P+ + T++
Sbjct: 1033 VETPVPPPAPATESAIASEQPETRPAET-AQPAMEETNTANSTETAPKSDTATQTENPNS 1091
Query: 135 TQLCSVKKKKKRKGA-ESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEP 193
+ S +K + + NE VA+ TEP G V E +P +T+
Sbjct: 1092 ESVPSETTEKVAENPPQENETVAKNEQEATEPTPQNGEVAKEDQPTVEANTQ-------- 1143
Query: 194 PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELD 253
E + E + E+ ++ P + ++ PEK ++ D
Sbjct: 1144 --------TNEATQSEGKTEETQTAETKSEPTESVTVS-ENQPEKT-------VSQSTED 1187
Query: 254 RRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGP-VIPVCPNS--ASLIG 310
+ +E A V ++E P+ V K P +Q +P P +P N+ A +
Sbjct: 1188 KVVVEKEEKAKVETEETQKAPQ---VTSKEPP-----KQAEPAPEEVPTDTNAEEAQALQ 1239
Query: 311 QSQ--TIPVVDTEQKINKRSRMSKMKRKRMNSMP------DKHNTEPPETKKRVLDREEP 362
Q+Q T+ +T +K + ++ ++ N+ P + T+P ET++ +E
Sbjct: 1240 QTQPTTVAAAETTSPNSKPAEETQQPSEKTNAEPVTPVVSENTATQPTETEETAKVEKE- 1298
Query: 363 NKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKS 422
K E +AS Q P PA P+ +T K + ++NVL ++
Sbjct: 1299 -----KTQEVPQVAS-----QESPKQEQPA--AKPQAQT--KPQAEPARENVLTTK---- 1340
Query: 423 NEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPK-HSEGKMSNAQRNNVLLS 481
N QP P +S + P+ T +P A K +E N N
Sbjct: 1341 NVGEPQPQAQPQTQSTA---VPTTGETAANSKPAAKPQAQAKPQTEPARENVSTVNTKEP 1397
Query: 482 EGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNK 541
+ S TE P +++ + ++ P+ + ++ T + K + +M +
Sbjct: 1398 QSQTSATVSTEQPAKETSSNVEQPAPENSINTGSATTMTETAEKSDKPQMETVTENDRQP 1457
Query: 542 RALKSAWSESVHHSSDQNAKTPVQRTES 569
A A + ++S +K+ +R+ S
Sbjct: 1458 EANTVADNSVANNSESSESKSRRRRSVS 1485
Score = 40.4 bits (93), Expect = 0.013
Identities = 78/357 (21%), Positives = 125/357 (34%), Gaps = 24/357 (6%)
Query: 5 SQSELLHSKKRRREEKPEPLPS-------PEQDQEQSCSKKKR-RKKKKIKEEGIESHEH 56
+QSE + + E K EP S PE+ QS K K++K K E E+ +
Sbjct: 1148 TQSEGKTEETQTAETKSEPTESVTVSENQPEKTVSQSTEDKVVVEKEEKAKVETEETQKA 1207
Query: 57 DQVLLPEPVVVATAIPITLETPKEQGAEPIEATV-VHPVPDQRPAKTHRKKKKKETVLEP 115
QV EP A P E P + AE +A P T K E +P
Sbjct: 1208 PQVTSKEPPKQAEPAPE--EVPTDTNAEEAQALQQTQPTTVAAAETTSPNSKPAEETQQP 1265
Query: 116 QPEPEPEPKE--TSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAV-QGGV 172
+ EP S ++PT+ K +K K E + ++ + +P A Q
Sbjct: 1266 SEKTNAEPVTPVVSENTATQPTETEETAKVEKEKTQEVPQVASQESPKQEQPAAKPQAQT 1325
Query: 173 LPEPKP-KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLA 231
P+ +P +E T P+P E N A P+A +P A
Sbjct: 1326 KPQAEPARENVLTTKNVGEPQPQAQPQTQSTAVPTTGETAANSKPAAKPQAQAKPQTEPA 1385
Query: 232 IPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQ 291
+N T +++ E+ +S+ + P + + + +
Sbjct: 1386 -----RENVSTVNTKEPQSQTSATVSTEQPAKETSSNVEQPAPENSINTGSATTMTETAE 1440
Query: 292 QTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTE 348
++ + V N Q + V D N S SK +R+R S P + + E
Sbjct: 1441 KSDKPQMETVTENDR----QPEANTVADNSVANNSESSESKSRRRRSVSQPKETSAE 1493
>TRDN_RABIT (Q28820) Triadin
Length = 705
Score = 56.6 bits (135), Expect = 2e-07
Identities = 108/544 (19%), Positives = 204/544 (36%), Gaps = 91/544 (16%)
Query: 10 LHSKKRRREEKPE-PLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVA 68
+H +K ++EKPE +P+ +E+ K+K ++K+K +++ + ++ PE V
Sbjct: 143 IHKEKIEKQEKPERKIPTKVVHKEKEKEKEKVKEKEKPEKKATHKEKLEKKEKPETKTV- 201
Query: 69 TAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVL---EPQPEPEPEPKE 125
T E K + E IE ++ K +++K K+TV E Q P+P+ KE
Sbjct: 202 -----TKEEKKARTKEKIEEKT------KKEVKGVKQEKVKQTVAKAKEVQKTPKPKEKE 250
Query: 126 TSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTE 185
+ T +V K++++ + ++ P Q +P P P E S
Sbjct: 251 SKET--------AAVSKQEQKDQYAFCRYMIDIFVHGDLKPG-QSPAIPPPSPTEQAS-- 299
Query: 186 HPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLT 245
P L P + E +K+AE + +A E K K E T
Sbjct: 300 ------RPTPALPTPEEKEGEKKKAEKKVTTETKKKAEKE----------DAKKKSEKET 343
Query: 246 PTDENELDRRNR--------REELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGP 297
D + + + A DEK + + P + P +Q+ +
Sbjct: 344 DIDMKKKEPGKSPDTKPGTVKVTTQAATKKDEKKEDSKKAKKPAEEQPK-GKKQEKKEKH 402
Query: 298 VIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVL 357
P S+ + KI ++ +S K+ ++P K + +T ++
Sbjct: 403 EEPAKSTKKEHAAPSEK----QAKAKIERKEEVSAASTKK--AVPAKKEEKTTKTVEQET 456
Query: 358 DREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHK--TPKKWKKRAKKKNVL 415
+E+P K ++ L D+ + + VP + + K KK +K +K + +
Sbjct: 457 RKEKPGKISSVLK-----------DKELTKEKEVKVPASLKEKGSETKKDEKTSKPEPQI 505
Query: 416 LSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQR 475
E E +P + ++K P +Q + T H GK
Sbjct: 506 KKEEKPGKEVKPKPPQPQIKKEEKP------------EQDIMKPEKTALH--GKPEEKVL 551
Query: 476 NNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQ 535
V + V + + P +K+ + K P P++ TD+P P+ +E K +
Sbjct: 552 KQV---KAVTTEKHVKPKPAKKAEHQEKEP---PSIKTDKPKSTSKGMPEVTESGKKKIE 605
Query: 536 RRKK 539
+ +K
Sbjct: 606 KSEK 609
Score = 48.9 bits (115), Expect = 4e-05
Identities = 93/489 (19%), Positives = 179/489 (36%), Gaps = 80/489 (16%)
Query: 6 QSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPV 65
+ + H +K ++EKPE + ++++++ +K+K +K K + +G++ + Q +
Sbjct: 181 EKKATHKEKLEKKEKPE-TKTVTKEEKKARTKEKIEEKTKKEVKGVKQEKVKQTVAKAKE 239
Query: 66 VVATAIP----------ITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEP 115
V T P ++ + K+Q A + D +P ++ T
Sbjct: 240 VQKTPKPKEKESKETAAVSKQEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPSPTEQAS 299
Query: 116 QPE---PEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGV 172
+P P PE KE + + KK +K + +E ++ EP G
Sbjct: 300 RPTPALPTPEEKEGEKKKAEKKVTTETKKKAEKEDAKKKSEKETDIDMKKKEP-----GK 354
Query: 173 LPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAE--PNESNAEHPRACPEPPLGL 230
P+ KP T + D +K +K AE P E EP
Sbjct: 355 SPDTKPGTVKVTTQAATKKDEK-----KEDSKKAKKPAEEQPKGKKQEKKEKHEEP---- 405
Query: 231 AIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLE 290
+ K E+ P+++ + R+EE+ A S +K V + K++ E
Sbjct: 406 -----AKSTKKEHAAPSEKQAKAKIERKEEVSA--ASTKKAVPAKKEEKTTKTV-----E 453
Query: 291 QQT---QPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNT 347
Q+T +PG + +S++ + + + + + + S+ K+ S P+
Sbjct: 454 QETRKEKPGKI-------SSVLKDKELTKEKEVKVPASLKEKGSETKKDEKTSKPE---- 502
Query: 348 EPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKK 407
P+ KK E+P K P + +Q I A+ PE K K+ K
Sbjct: 503 --PQIKK----EEKPGKEVKPKPPQPQIKKEEKPEQDIMKPEKTALHGKPEEKVLKQVKA 556
Query: 408 RAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSE 467
+K+V K+ +P P++ TD+P P+ +E
Sbjct: 557 VTTEKHVKPKPAKKAEHQEKEP------------------PSIKTDKPKSTSKGMPEVTE 598
Query: 468 GKMSNAQRN 476
+++
Sbjct: 599 SGKKKIEKS 607
Score = 48.5 bits (114), Expect = 5e-05
Identities = 60/277 (21%), Positives = 106/277 (37%), Gaps = 32/277 (11%)
Query: 332 KMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSD--- 388
K K K + +K E T K L+++E + E + I++ +
Sbjct: 165 KEKEKEKEKVKEKEKPEKKATHKEKLEKKEKPETKTVTKEEKKARTKEKIEEKTKKEVKG 224
Query: 389 ------SNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHN--GQPTETPVQKSVSP 440
KTPK K++ K+ +S+ + +++ + V + P
Sbjct: 225 VKQEKVKQTVAKAKEVQKTPKP-KEKESKETAAVSKQEQKDQYAFCRYMIDIFVHGDLKP 283
Query: 441 INAPSIDPTLPTDQ---PVPIDLATPKHSEGKMSNAQ-------RNNVLLSEGVKSNEQP 490
+P+I P PT+Q P P L TP+ EG+ A+ + + K +E+
Sbjct: 284 GQSPAIPPPSPTEQASRPTPA-LPTPEEKEGEKKKAEKKVTTETKKKAEKEDAKKKSEKE 342
Query: 491 TETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSK-----AQRRKKNKRALK 545
T+ ++K P K+P T P V AT K + + SK A+ + K K+ K
Sbjct: 343 TDIDMKKK-EPGKSPD---TKPGTVKVTTQAATKKDEKKEDSKKAKKPAEEQPKGKKQEK 398
Query: 546 SAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVKAKS 582
E S+ + P ++ K+ + V A S
Sbjct: 399 KEKHEEPAKSTKKEHAAPSEKQAKAKIERKEEVSAAS 435
Score = 39.3 bits (90), Expect = 0.029
Identities = 54/243 (22%), Positives = 88/243 (35%), Gaps = 32/243 (13%)
Query: 348 EPPETKKRVLDR--EEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKW 405
EPP +K + E+ K K+P ++ + + P + K KK
Sbjct: 135 EPPLKRKDIHKEKIEKQEKPERKIPTKVVHKEKEKEKEKVKEKEKPEKKATHKEKLEKKE 194
Query: 406 KKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKH 465
K K + E K+ + E +K V + + T+ + V PK
Sbjct: 195 KPETK---TVTKEEKKARTK--EKIEEKTKKEVKGVKQEKVKQTVAKAKEVQ-KTPKPKE 248
Query: 466 SEGKMSNAQRNNVLLSEGVKSNEQPTETP---------VQKSVNPIKAPSIDPTLPTDQ- 515
E K + A V EQ + V + P ++P+I P PT+Q
Sbjct: 249 KESKETAA----------VSKQEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPSPTEQA 298
Query: 516 --PVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLV 573
P P L TP+ EG+ KA+ +K K A E S++ +++ E K
Sbjct: 299 SRPTPA-LPTPEEKEGEKKKAE-KKVTTETKKKAEKEDAKKKSEKETDIDMKKKEPGKSP 356
Query: 574 EAK 576
+ K
Sbjct: 357 DTK 359
>SSP2_PLAYO (Q01443) Sporozoite surface protein 2 precursor
Length = 827
Score = 55.1 bits (131), Expect = 5e-07
Identities = 94/439 (21%), Positives = 145/439 (32%), Gaps = 122/439 (27%)
Query: 92 HPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAES 151
+P P +R K K K +P P +P P E SN + P + + K + +
Sbjct: 389 NPNPKKRNPKRRNPNKPKPN--KPNPN-KPNPNEPSNPNKPNPNEPSNPNKPNPNEPSNP 445
Query: 152 NEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAE 211
N +P P EP + P P PL P +P + +
Sbjct: 446 N----------------------KPNPNEPSNPNKPN--PNEPLN---PNEPSNPNEPSN 478
Query: 212 PNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEKI 271
PN + + + P P P +P + P++ NE ++ +K
Sbjct: 479 PNAPSNPNEPSNPNEPSNPNEPSNPNE-------PSNPNE-------------PSNPKKP 518
Query: 272 VNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMS 331
NP + S P L P P PN S + E+ N +
Sbjct: 519 SNPNE-----PSNPNEPLNPNEPSNPNEPSNPNEPS-----------NPEEPSNPK---- 558
Query: 332 KMKRKRMNSMPDKHNTEPPETKKRVLDREE---PNKCNAKLPETLMLASNCHIDQAIPSD 388
+ S P++ N E P K + EE P + N K P P +
Sbjct: 559 EPSNPNEPSNPEEPNPEEPSNPKEPSNPEEPINPEELNPKEPSN-------------PEE 605
Query: 389 SNPAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPI------- 441
SNP P NPE PK+ +N L+ + +P E +V PI
Sbjct: 606 SNPKEPINPEESNPKEPINPEDNENPLIIQ--------DEPIEPRNDSNVIPILPIIPQK 657
Query: 442 --NAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSV 499
N PS P P+D V ++ + NN + S+ NE
Sbjct: 658 GNNIPSNLPENPSDSEV-------EYPRPNDNGENSNNTMKSKKNIPNE----------- 699
Query: 500 NPIKAPSIDPTLPTDQPVP 518
PI +P +P ++ +P
Sbjct: 700 -PIPSPGDNPYKGHEERIP 717
Score = 52.0 bits (123), Expect = 4e-06
Identities = 94/405 (23%), Positives = 142/405 (34%), Gaps = 34/405 (8%)
Query: 132 SEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQ---GGVLPEPKPKEPCSTEHPR 188
SE + C +K +R+ V+E+ T C Q V+P P++P + E P
Sbjct: 245 SECSTTCDEGRKIRRRQILHPGCVSEMTTPCKVRDCPQIPIPPVIPNKIPEKPSNPEEP- 303
Query: 189 VCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENL---- 244
V P P P +P PN N + P P P +P N
Sbjct: 304 VNPNDPNDPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNP 363
Query: 245 ----TPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIP 300
P + N + N + + K NP+ P K P +P P P
Sbjct: 364 NNPNNPNNPNNPNNPNNPNDPSNPNNPNPKKRNPKRRN-PNKPKPN--KPNPNKPNPNEP 420
Query: 301 VCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDRE 360
PN + P + N+ S +K ++ P+K N P +
Sbjct: 421 SNPNKPN-----PNEPSNPNKPNPNEPSNPNKPNPNEPSN-PNKPNPNEPLNPNEPSNPN 474
Query: 361 EPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNP-EHKTPKKWKK--RAKKKNVLLS 417
EP+ NA P SN + SNP P+NP E PKK N L+
Sbjct: 475 EPSNPNA--PSNPNEPSNPNEPSNPNEPSNPNEPSNPNEPSNPKKPSNPNEPSNPNEPLN 532
Query: 418 EGGKSNEHN-GQPTETPVQKSVSPINAPSIDPTLPT--DQPVPIDLATPKHSEGKMSNAQ 474
SN + P E + S PS +P P+ ++P P + + PK SN +
Sbjct: 533 PNEPSNPNEPSNPNEPSNPEEPSNPKEPS-NPNEPSNPEEPNPEEPSNPKEP----SNPE 587
Query: 475 RNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPI 519
K P E+ ++ +NP ++ +P P D P+
Sbjct: 588 EPINPEELNPKEPSNPEESNPKEPINPEESNPKEPINPEDNENPL 632
Score = 48.5 bits (114), Expect = 5e-05
Identities = 79/380 (20%), Positives = 138/380 (35%), Gaps = 54/380 (14%)
Query: 78 PKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQL 137
PK P + P +P K EP +P P E SN + P +
Sbjct: 405 PKPNKPNPNKPNPNEPSNPNKPNPNEPSNPNKPNPNEPSNPNKPNPNEPSNPNKPNPNEP 464
Query: 138 C-----SVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLP----EP-KPKEPCSTEHP 187
S + A SN + P P EP PK+P + P
Sbjct: 465 LNPNEPSNPNEPSNPNAPSNPNEPSNPNEPSNPNEPSNPNEPSNPNEPSNPKKPSNPNEP 524
Query: 188 RVCPEP--------------PLGLAIPIDPEKNRKEAEPNE-SNAEHPRACPEPPLGLAI 232
EP P + P +P ++ + PNE SN E P PE P
Sbjct: 525 SNPNEPLNPNEPSNPNEPSNPNEPSNPEEPSNPKEPSNPNEPSNPEEPN--PEEPSNPKE 582
Query: 233 PIDPEKN-KGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQ 291
P +PE+ E L P + + + N +E + ++ ++ +NP D+ PL + ++
Sbjct: 583 PSNPEEPINPEELNPKEPSNPEESNPKEPINPEESNPKEPINPEDNENPL-----IIQDE 637
Query: 292 QTQPG------PVIPVCPNSASLIGQSQTIPVVDTE---QKINKRSRMSKMKRKRMNSMP 342
+P P++P+ P + I + D+E + N S K ++P
Sbjct: 638 PIEPRNDSNVIPILPIIPQKGNNIPSNLPENPSDSEVEYPRPNDNGENSNNTMKSKKNIP 697
Query: 343 DKHNTEPPETKKRVLDRE--EPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHK 400
++ P + + + +P++ N + + +N + + + P +P N E++
Sbjct: 698 NEPIPSPGDNPYKGHEERIPKPHRSN----DDYVYDNNVNKN----NKDEPEIPNN-EYE 748
Query: 401 TPKKWKKRAKKKNVLLSEGG 420
K K ++K N GG
Sbjct: 749 EDKN-KNQSKSNNGYKIAGG 767
Score = 41.6 bits (96), Expect = 0.006
Identities = 62/289 (21%), Positives = 99/289 (33%), Gaps = 14/289 (4%)
Query: 297 PVIPVCPNSASLIGQSQTIPVV--DTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKK 354
P+ PV PN + PV D N + + N+ + +N P
Sbjct: 284 PIPPVIPNKIPEKPSNPEEPVNPNDPNDPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPN 343
Query: 355 RVLDREEPNKCN-AKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKN 413
+ PN N P +N + + +NP P+NP + PK K+ K++N
Sbjct: 344 NPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNNPNDPSNPNNPNPK--KRNPKRRN 401
Query: 414 VLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNA 473
+ K N + P E +P N PS +P P P + P +E N
Sbjct: 402 PNKPKPNKPNPNKPNPNEPSNPNKPNP-NEPS-NPNKPNPNE-PSNPNKPNPNEPSNPNK 458
Query: 474 QRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSK 533
N L+ SN P S NP +P+ P + P + + P
Sbjct: 459 PNPNEPLNPNEPSNPNEPSNPNAPS-NP-----NEPSNPNEPSNPNEPSNPNEPSNPNEP 512
Query: 534 AQRRKKNKRALKSAWSESVHHSSDQNAKTPVQRTESLKLVEAKSVKAKS 582
+ +K + S +E ++ + N P E E + K S
Sbjct: 513 SNPKKPSNPNEPSNPNEPLNPNEPSNPNEPSNPNEPSNPEEPSNPKEPS 561
>DD21_MOUSE (Q9JIK5) Nucleolar RNA helicase II (Nucleolar RNA
helicase Gu) (RH II/Gu) (DEAD-box protein 21)
Length = 851
Score = 52.4 bits (124), Expect = 3e-06
Identities = 68/275 (24%), Positives = 105/275 (37%), Gaps = 42/275 (15%)
Query: 18 EEKPEPLPSPEQDQEQSCSKKKRRKKKKIK-EEGIESHEHDQVLLPEPVVVATAIPITLE 76
EE E LP P + KK R++K K K EE E E V + A +
Sbjct: 17 EESMETLPKPSE-------KKTRKEKTKSKTEEATEGMEE--------AVSSKAKKTNKK 61
Query: 77 TPKEQGAEPIE---ATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSE 133
P E +P + A P A T + KKK+ LE Q + E + T E
Sbjct: 62 GPSEDDVDPPKSRKAKKQEEEPQDDTASTSKTSKKKKEPLEKQADSETKEIITEEPSEEE 121
Query: 134 PTQLCSVKKKKKRKGAESN----EAVAELATVCTEPPAVQGGVLPEPKPK-----EPCST 184
K KK +KG E+N E +L ++P + + PKPK + +
Sbjct: 122 ADM---PKPKKMKKGKEANGDAGEKSPKLKNGLSQPSEEEADI---PKPKKMKKGKEANG 175
Query: 185 EHPRVCPEPPLGLAIP----IDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNK 240
+ P+ GL+ P +D K +K + E++ + P GL+ P +P+ N
Sbjct: 176 DAGEKSPKLKNGLSQPSEEEVDIPKPKKMKKGKEASGDAGEKSPRLKDGLSQPSEPKSNS 235
Query: 241 ----GENLTPTDENELDRRNRREELVALVTSDEKI 271
GE + E E+ + S+E +
Sbjct: 236 SDAPGEESSSETEKEIPVEQKEGAFSNFPISEETV 270
Score = 35.4 bits (80), Expect = 0.42
Identities = 50/248 (20%), Positives = 93/248 (37%), Gaps = 33/248 (13%)
Query: 320 TEQKINKRSRMSKMKRKRMNSM-PDKHNTEPPETKKRVLDREEP-------NKCNAKLPE 371
TE+ K K+ N P + + +PP+++K EEP +K + K E
Sbjct: 40 TEEATEGMEEAVSSKAKKTNKKGPSEDDVDPPKSRKAKKQEEEPQDDTASTSKTSKKKKE 99
Query: 372 TLMLASNCHIDQAI---PSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSEG-GKSNEHNG 427
L ++ + I PS+ +P + K K+ A +K+ L G + +E
Sbjct: 100 PLEKQADSETKEIITEEPSEEEADMPKPKKMKKGKEANGDAGEKSPKLKNGLSQPSEEEA 159
Query: 428 QPTETPVQKSVSPIN------APSIDPTLPTDQPVPIDLATPKH-SEGK--MSNAQRNNV 478
+ K N +P + L +D+ PK +GK +A +
Sbjct: 160 DIPKPKKMKKGKEANGDAGEKSPKLKNGLSQPSEEEVDIPKPKKMKKGKEASGDAGEKSP 219
Query: 479 LLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRK 538
L +G+ +P N AP + + T++ +P++ EG S +
Sbjct: 220 RLKDGLSQPSEPKS-------NSSDAPGEESSSETEKEIPVE-----QKEGAFSNFPISE 267
Query: 539 KNKRALKS 546
+ + LK+
Sbjct: 268 ETVKLLKA 275
>PCLO_MOUSE (Q9QYX7) Piccolo protein (Presynaptic cytomatrix protein)
(Aczonin) (Brain-derived HLMN protein)
Length = 5038
Score = 52.0 bits (123), Expect = 4e-06
Identities = 121/560 (21%), Positives = 195/560 (34%), Gaps = 96/560 (17%)
Query: 77 TPKEQGAEPIEAT----VVHPVPDQR---PAKTHRKKKKKETVLEPQPEPEPEPKETSNT 129
TP + A P A+ V HP P P + + KK +T + P+P+ +P PK +
Sbjct: 727 TPLDSKAMPRPASDSKIVSHPGPTSESKDPVQKKEEPKKAQTKVTPKPDTKPVPKGSPTP 786
Query: 130 DHSEPT--QLCSVKKKKKRKGAESNEAVAELATVCTEPPA--------VQG-----GVLP 174
+ PT Q ++ + +S L + P + V G G
Sbjct: 787 SGTRPTTGQATPQSQQPPKPPEQSRRFSLNLGGIADAPKSQPTTPQETVTGKLFGFGASI 846
Query: 175 EPKPKEPCST-----EHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLG 229
+ ST HP+ P P A P P + P +S +HP A
Sbjct: 847 FSQASNLISTAGQQAPHPQTGPAAPSKQAPP--PSQTLAAQGPPKSTGQHPSA------- 897
Query: 230 LAIPIDPEKNKGENLTPTDENELDRRNRREELVALVTSDEK----IVNPRDHLVPLKSIP 285
P K E P EN L+ + + V D+K V+ P K++
Sbjct: 898 ---PAKTTAVKKETKGPAAEN-LEAKPAQAPTVKKAEKDKKHPPGKVSKPPPTEPEKAVL 953
Query: 286 GFVLEQQTQPGPVIPVC-----------PN----------SASLIGQSQTIPVVDTEQKI 324
++ T+P P P+C PN +L G + T + + ++ +
Sbjct: 954 AQKPDKTTKPKPACPLCRTELNVGSQDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWL 1013
Query: 325 ---NKRSRMSKMKRKRMNSMPDKHN---TEPPETKKRVLDREEPNKCNA--KLPETLMLA 376
+ R + M+ MP + P ++ P +A K ET + A
Sbjct: 1014 CLNCQTQRAISGQLGDMDKMPPASSGPKASPVPAPAEPPPQKTPTAAHAKGKKKETEVKA 1073
Query: 377 SNCHIDQAIPSDSNPAV-PTNPEHKTPKKWKKRAKKKNV--LLSEGGKSNEHNGQPTETP 433
++ IP P++ T P T +K ++ K++ +L E S E P +
Sbjct: 1074 ET---EKQIPEKETPSIEKTPPAVATDQKLEESEVTKSLVSVLPEKKPSEEEKALPAD-- 1128
Query: 434 VQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQ---- 489
+K P A + P L +P+P D P ++ S + LL V+ E+
Sbjct: 1129 -KKEKKPPAAEA--PPLEEKKPIPDDQKLPPDAKPSASEGEEKRDLLKAHVQIPEEGPIG 1185
Query: 490 -----PTETPVQKSVNPIKAPSIDP-TLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRA 543
E Q P P P TLP D+ T +EG + + R
Sbjct: 1186 KVASLACEGEQQPDTRPEDLPGATPQTLPKDRQKESRDVTQPQAEGTAKEGRGEPSKDRT 1245
Query: 544 LKSAWSESVHHSSDQNAKTP 563
K + SS Q K+P
Sbjct: 1246 EKE--EDKSDTSSSQQPKSP 1263
Score = 50.1 bits (118), Expect = 2e-05
Identities = 46/176 (26%), Positives = 74/176 (41%), Gaps = 23/176 (13%)
Query: 83 AEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKK 142
A P+ A P P + P H K KKKET ++ + E + KET + + + P K
Sbjct: 1042 ASPVPAPA-EPPPQKTPTAAHAKGKKKETEVKAETEKQIPEKETPSIEKTPPAVATDQK- 1099
Query: 143 KKKRKGAESNEAVAELATVCTE-PPAVQGGVLP-EPKPKEPCSTEHPRVCPEPPLGLAIP 200
E +E L +V E P+ + LP + K K+P + E P + + P+
Sbjct: 1100 ------LEESEVTKSLVSVLPEKKPSEEEKALPADKKEKKPPAAEAPPLEEKKPIP---- 1149
Query: 201 IDPEKNRKEAEPNESNAE--------HPRACPEPPLGLAIPIDPEKNKGENLTPTD 248
D +K +A+P+ S E H + E P+G + E + + P D
Sbjct: 1150 -DDQKLPPDAKPSASEGEEKRDLLKAHVQIPEEGPIGKVASLACEGEQQPDTRPED 1204
Score = 47.4 bits (111), Expect = 1e-04
Identities = 108/485 (22%), Positives = 158/485 (32%), Gaps = 60/485 (12%)
Query: 62 PEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEP 121
P P P T + P +Q + V P P + PA+ K P +P P
Sbjct: 340 PGPAKSPAQQPGTAKLPAQQPGPQTASKV--PGPTKTPAQLSGPGKT------PAQQPGP 391
Query: 122 EPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEP 181
++P V K + + + + T P P+P+ P
Sbjct: 392 TKPSPQQPIPAKPQPQQPVATKPQPQQPAPAKPQPQHPTPAKPQPQQPTPAKPQPQQPTP 451
Query: 182 CSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPL-GLAIPIDPEKNK 240
+ P LG P K+ + P + + P GL+ I P N
Sbjct: 452 AKPQPQH----PGLGKPSAQQPSKSISQTVTGRPLQAPPTSAAQAPAQGLSKTICPLCNT 507
Query: 241 GENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIP 300
E L T E N E + V S NP HL +K + Q G +
Sbjct: 508 TELLLHTPEKA--NFNTCTECQSTVCSLCGF-NPNPHLTEIKEWLCLNCQMQRALGGELA 564
Query: 301 VCPNS-------ASLIGQSQTIPVVDTEQKINKRSRMSKM---------KRKRMNSMPDK 344
P+S AS+ + + V ++Q K+ SK K + P
Sbjct: 565 AIPSSPQPTPKAASVQPATASKSPVPSQQASPKKELPSKQDSPKAPESKKPPPLVKQPTL 624
Query: 345 HNTEP-----PETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEH 399
H P P + + P K +A LPE +A +D P P E
Sbjct: 625 HGPTPATAPQPPVAEALPKPAPPKKPSAALPEQA---------KAPVADVEPKQPKTTET 675
Query: 400 KTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPID 459
T A K +LS ++ Q T P K+ S + S PT D
Sbjct: 676 LTDSPSSAAATSKPAILSSQVQAQ---AQVTTAPPLKTDSAKTSQSFPPTG--------D 724
Query: 460 LATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPI 519
TP S+ A + ++ G S ++ PVQK P KA + P +PVP
Sbjct: 725 TITPLDSKAMPRPASDSKIVSHPGPTSE---SKDPVQKKEEPKKAQTKVTPKPDTKPVPK 781
Query: 520 DLATP 524
TP
Sbjct: 782 GSPTP 786
Score = 40.4 bits (93), Expect = 0.013
Identities = 90/422 (21%), Positives = 146/422 (34%), Gaps = 98/422 (23%)
Query: 93 PVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESN 152
P P PA ++ L Q P+ ++ S P + +VKK+ K AE+
Sbjct: 862 PHPQTGPAAPSKQAPPPSQTLAAQGPPK-----STGQHPSAPAKTTAVKKETKGPAAENL 916
Query: 153 EAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEP 212
EA A P K E P +PP P +PEK +P
Sbjct: 917 EAKPAQA--------------PTVKKAEKDKKHPPGKVSKPP-----PTEPEKAVLAQKP 957
Query: 213 NESNAEHPRACP--EPPLGLAIPIDPEKN-----KGENLTPTDENELDRRNRREELVALV 265
+++ P ACP L + P N K + N +E + L
Sbjct: 958 DKTTKPKP-ACPLCRTELNVGSQDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1016
Query: 266 TSDEKIVNPR----DHLVPLKSIPGFVLEQQTQPGPVIPV---CPNSASLIGQSQ----- 313
++ ++ + D + P S P + P P P P +A G+ +
Sbjct: 1017 CQTQRAISGQLGDMDKMPPASSGP----KASPVPAPAEPPPQKTPTAAHAKGKKKETEVK 1072
Query: 314 -----------------TIPVVDTEQKINK----RSRMSKMKRKRMN----SMP-DKHNT 347
T P V T+QK+ + +S +S + K+ + ++P DK
Sbjct: 1073 AETEKQIPEKETPSIEKTPPAVATDQKLEESEVTKSLVSVLPEKKPSEEEKALPADKKEK 1132
Query: 348 EPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKK 407
+PP + L+ ++P +P+ DQ +P D+ P+ E K+
Sbjct: 1133 KPPAAEAPPLEEKKP------IPD----------DQKLPPDAKPSASEGEE-------KR 1169
Query: 408 RAKKKNVLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDP-TLPTDQPVPIDLATPKHS 466
K +V + E G + E Q P + P P TLP D+ T +
Sbjct: 1170 DLLKAHVQIPEEGPIGKVASLACEGEQQPDTRPEDLPGATPQTLPKDRQKESRDVTQPQA 1229
Query: 467 EG 468
EG
Sbjct: 1230 EG 1231
Score = 31.6 bits (70), Expect = 6.0
Identities = 92/471 (19%), Positives = 153/471 (31%), Gaps = 53/471 (11%)
Query: 132 SEPTQLCSVKKKK-KRKGAESNEAVAELATVCTEP---PAVQGG---VLPEPKPKEPCST 184
SE Q + KK+K +K +E + + + P P QG V+P+ P + S+
Sbjct: 179 SEAVQEETTKKQKVAQKDQGKSEGITKPSLQQPSPKLIPKQQGPGKEVIPQDIPSKSVSS 238
Query: 185 EHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHP---RACPEPPLGLAIPIDPEKNKG 241
+ G A P + A+ + A+ P +A + P P P
Sbjct: 239 QQAEKTKPQAPGTAKPSQQSPAQTPAQQAKPVAQQPGPAKATVQQPGPAKSPAQPAGTGK 298
Query: 242 ENLTPTDENELDRRNRREELVALVTSDEKIV--NPRDHLVPLKSIPGFVLEQQTQPG--- 296
P + + E +L K + P VP PG QPG
Sbjct: 299 SPAQPPVTAKPPAQQAGLEKTSLQQPGPKSLAQTPGQGKVP----PGPAKSPAQQPGTAK 354
Query: 297 -PVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKR 355
P P +AS + P + + K +P K + P K
Sbjct: 355 LPAQQPGPQTASKVPGPTKTPAQLSGPGKTPAQQPGPTKPSPQQPIPAKPQPQQPVATKP 414
Query: 356 VLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPT--NPEHKTPKKWKKRAKKKN 413
+ P K + P + Q P+ P PT P+ + P K A++ +
Sbjct: 415 QPQQPAPAKPQPQHPTP----AKPQPQQPTPAKPQPQQPTPAKPQPQHPGLGKPSAQQPS 470
Query: 414 VLLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTL-PTDQPVPIDLATPKHSEGKMSN 472
+S+ G+P + P S + A + T+ P + L TP+ +
Sbjct: 471 KSISQ-----TVTGRPLQAP-PTSAAQAPAQGLSKTICPLCNTTELLLHTPEKANFNTCT 524
Query: 473 AQRNNVLLSEGVKSNEQPTE-------------------TPVQKSVNPI-KAPSIDPTLP 512
++ V G N TE + S P KA S+ P
Sbjct: 525 ECQSTVCSLCGFNPNPHLTEIKEWLCLNCQMQRALGGELAAIPSSPQPTPKAASVQPATA 584
Query: 513 TDQPVPIDLATPKHSEGKMSKAQRRKKNKRALKSAWSESVHHSSDQNAKTP 563
+ PVP A+PK + + ++K+ ++H + A P
Sbjct: 585 SKSPVPSQQASPKKELPSKQDSPKAPESKKPPPLVKQPTLHGPTPATAPQP 635
>NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 kDa
protein) (140 kDa nucleolar phosphoprotein) (Nopp140)
(Nucleolar and coiled-body phosphoprotein 1)
Length = 704
Score = 51.6 bits (122), Expect = 6e-06
Identities = 109/565 (19%), Positives = 207/565 (36%), Gaps = 67/565 (11%)
Query: 20 KPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETPK 79
K P + +KK +++ S E D+ +P A A +L P+
Sbjct: 59 KSTKAPKVKLQSNGPVAKKAKKETSSSDSSEDSSEEEDKAQVPTQKAAAPAKRASL--PQ 116
Query: 80 EQG---AEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPE---PEPEPKETSNTDHSE 133
G A+ E++ ++ K +KK ++ ++PQ + P P+ E+S ++
Sbjct: 117 HAGKAAAKASESSSSEESSEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDS 176
Query: 134 PTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEP 193
++ + + +K + A + +A + T+ PA G P +P +
Sbjct: 177 SSEDEAPQTQKPKAAATAAKAPTKAQ---TKAPAKPG----PPAKAQPKAANGKAGSSSS 229
Query: 194 PLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTPTDENELD 253
+ D E+ +K A P + A + + P+ + + + E+ + +E E
Sbjct: 230 SSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQK 289
Query: 254 RRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPVIPVCPNSASLIGQSQ 313
+ +++ P + P P L +++ V P A+ +Q
Sbjct: 290 KPMKKK------------AGPYSSVPP----PSVSLSKKS----VGAQSPKKAA----AQ 325
Query: 314 TIPVVDTEQKINKRSRMSKMKRKR--MNSMPDKHNTEPPETKKRV---LDREEPNKCNAK 368
T P D+ ++ S S + K+ ++ K +P KK+ D + + +
Sbjct: 326 TQP-ADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSEDE 384
Query: 369 LPETLMLASNCHIDQAIPSDSNPAV-PTNPEHK---TPKKWKKRAKKKNVLLSEGGKSNE 424
P + A+ + S PAV P P K TPK+ +K ++ S E
Sbjct: 385 APAKPVSATKSPL-------SKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEE 437
Query: 425 HNGQPTETPVQKSVSPINA---PSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLS 481
+ E +KSV+ A P+LP Q + SE S ++
Sbjct: 438 ESSSSEEEATKKSVTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKP 497
Query: 482 EGVK---SNEQPTETPVQKSV--NPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQR 536
K P TPV+K+ + + S + + ++ P ATPK GK +
Sbjct: 498 PAKKKAAGAAVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPA 557
Query: 537 RKKNKRALKSAWSESVHHSSDQNAK 561
+ K + SE ++QN K
Sbjct: 558 SQNGKAGKE---SEEEEEDTEQNKK 579
Score = 45.4 bits (106), Expect = 4e-04
Identities = 84/450 (18%), Positives = 154/450 (33%), Gaps = 65/450 (14%)
Query: 117 PEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
P + KETS++D SE + E A++ T PA + LP+
Sbjct: 73 PVAKKAKKETSSSDSSEDSS--------------EEEDKAQVPTQKAAAPAKRAS-LPQH 117
Query: 177 KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDP 236
K E + E+ K+ +P + A P+A P P
Sbjct: 118 AGKAAAKASESSSSEESSE------EEEEKDKKKKPVQQKAVKPQAKAVRP--------P 163
Query: 237 EKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPG 296
K + + +D + D + ++ A T+ K P K P + + G
Sbjct: 164 PKKAESSESESDSSSEDEAPQTQKPKAAATA-AKAPTKAQTKAPAKPGPPAKAQPKAANG 222
Query: 297 PVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRV 356
S+S S + + E+K + + K++ + P K P +
Sbjct: 223 KA-----GSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSS 277
Query: 357 LDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLL 416
D + K P + ++P S + ++PKK + + +
Sbjct: 278 EDSSSEEEEEQKKP----MKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSA 333
Query: 417 SEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRN 476
+S+ + + +TP + VS A +P P+ S+ S++
Sbjct: 334 DSSEESDSSSEEEKKTPAKTVVSKTPA----------KPAPVKKKAESSSDSSDSDS--- 380
Query: 477 NVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKAQR 536
S ++ PV + +P+ P++ P P + V ATPK G K Q
Sbjct: 381 ---------SEDEAPAKPVSATKSPLSKPAVTPKPPAAKAV----ATPKQPAGSGQKPQS 427
Query: 537 RKKNKRALKSAWSESVHHSSDQNAKTPVQR 566
RK + + + S S ++ ++ TP R
Sbjct: 428 RKADSSSSEEESSSSEEEATKKSVTTPKAR 457
Score = 40.4 bits (93), Expect = 0.013
Identities = 105/555 (18%), Positives = 186/555 (32%), Gaps = 65/555 (11%)
Query: 5 SQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEP 64
S SE ++ +++K +P+ + + +K + + E S E + +P
Sbjct: 129 SSSEESSEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDSSSEDEAPQTQKP 188
Query: 65 VVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPK 124
ATA + + A+P P + A + + E E K
Sbjct: 189 KAAATAAKAPTKAQTKAPAKPGPPAKAQP----KAANGKAGSSSSSSSSSSSDDSEEEKK 244
Query: 125 ETSNTDHSEPTQLCSVKKKKK------RKGAESNEAVAELATVCTEPPAVQGGVLPEPKP 178
+ + P + K K +K + S ++ +E +P + G P
Sbjct: 245 AAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVPP 304
Query: 179 KEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEK 238
++ P A + + +E ++S++E + P + P P
Sbjct: 305 PSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAP 364
Query: 239 NKGENLTPTDENELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQPGPV 298
K + + +D ++ D + +E A S K PL P
Sbjct: 365 VKKKAESSSDSSDSD--SSEDEAPAKPVSATK--------SPLSK-------------PA 401
Query: 299 IPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLD 358
+ P +A V +Q + K +S + ++E TKK V
Sbjct: 402 VTPKPPAAK--------AVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKSVTT 453
Query: 359 REEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLSE 418
+ A A D + S+S+ + E KTP K AKKK +
Sbjct: 454 PKARVTAKAAPSLPAKQAPRAGGDSSSDSESS---SSEEEKKTPP--KPPAKKK----AA 504
Query: 419 GGKSNEHNGQPTETPVQKSV--SPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSN--AQ 474
G P TPV+K+ S ++ S + + ++ P ATPK GK + A
Sbjct: 505 GA------AVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPAS 558
Query: 475 RNNVLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPTDQPVPIDLATPKHSEGKMSKA 534
+N G +S E+ +T K K S + + ATP+ + K+
Sbjct: 559 QNG---KAGKESEEEEEDTEQNKKAAGTKPGSGKKRKHNE--TADEAATPQSKKVKLQTP 613
Query: 535 QRRKKNKRALKSAWS 549
K K+ K A S
Sbjct: 614 NTFPKRKKGEKRASS 628
Score = 32.7 bits (73), Expect = 2.7
Identities = 48/265 (18%), Positives = 92/265 (34%), Gaps = 19/265 (7%)
Query: 320 TEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNC 379
+E++ K + +++K + P PP K + E + + P+T +
Sbjct: 135 SEEEEEKDKKKKPVQQKAVK--PQAKAVRPPPKKAESSESESDSSSEDEAPQTQKPKAAA 192
Query: 380 HIDQAIPSDSN---PAVPTNPEHKTPKKWKKRAKKKNVLLSEGGKSNEHNGQPTETPVQK 436
+A P+ + PA P P PK +A + S + + P++K
Sbjct: 193 TAAKA-PTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKK 251
Query: 437 SVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQ 496
+ + P T P ++ + S + Q+ + G S+ P +
Sbjct: 252 TAPKKQVVAKAPVKVTAAPTQKS-SSSEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVSLS 310
Query: 497 KSVNPIKAP------------SIDPTLPTDQPVPIDLATPKHSEGKMSKAQRRKKNKRAL 544
K ++P S D + +D + TP + + A+ K+A
Sbjct: 311 KKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAE 370
Query: 545 KSAWSESVHHSSDQNAKTPVQRTES 569
S+ S S D+ PV T+S
Sbjct: 371 SSSDSSDSDSSEDEAPAKPVSATKS 395
>NFM_CHICK (P16053) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M)
Length = 857
Score = 51.6 bits (122), Expect = 6e-06
Identities = 72/294 (24%), Positives = 114/294 (38%), Gaps = 50/294 (17%)
Query: 1 MDSHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKI--KEEGIESHEH-- 56
++ + SE + EEK E E+ + +++ KK++I KEEG E+ E
Sbjct: 495 VEEEAVSEKAAEQAAEEEEKEEEEAEEEEAAKSDAAEEGGSKKEEIEEKEEGEEAEEEEA 554
Query: 57 -------------DQVLLPEPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTH 103
++V P + P ++P + A+ ++ DQ+ K
Sbjct: 555 EAKGKAEEAGAKVEKVKSPPAKSPPKSPP---KSPVTEQAKAVQKAAAEVGKDQKAEKAA 611
Query: 104 RKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCT 163
K K+E PE PK TS + P K +A+
Sbjct: 612 EKAAKEEKA--ASPEKPATPKVTSPEKPATP-----------EKPPTPEKAITPEKVRSP 658
Query: 164 EPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEHPRAC 223
E P V+ P++P S E PR PE P P PEK R +P + E PR+
Sbjct: 659 EKPTTPEKVV---SPEKPASPEKPRT-PEKPASPEKPATPEKPRTPEKP--ATPEKPRS- 711
Query: 224 PEPPLGLAIPIDPEKN-KGENLTPTD------ENELDRRNRREELVALVTSDEK 270
PE P + P+ EK E++T T E E+ + R+E++ +EK
Sbjct: 712 PEKP---SSPLKDEKAVVEESITVTKVTKVTAEVEVSKEARKEDIAVNGEVEEK 762
>UN89_CAEEL (O01761) Muscle M-line assembly protein unc-89
(Uncoordinated protein 89)
Length = 6632
Score = 51.2 bits (121), Expect = 7e-06
Identities = 106/510 (20%), Positives = 192/510 (36%), Gaps = 60/510 (11%)
Query: 93 PVPDQR---PAKTHRK-----KKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKK 144
P PD++ P KT K KK E V P+ + P + + +E VK
Sbjct: 1377 PSPDKKEKSPEKTEEKPASPTKKTGEEVKSPKEKSPASPTKKEKSPAAE-----EVKSPT 1431
Query: 145 KRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPE 204
K++ + S+ E + + P G + E P P S PE P + P+ E
Sbjct: 1432 KKEKSPSSPTKKEKSP--SSPTKKTGDEVKEKSP--PKSPTKKEKSPEKPEDVKSPVKKE 1487
Query: 205 KNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKG---ENLTPTDENELDRRNRREEL 261
K+ E ++E E + + + E+++ + TP +E + +++
Sbjct: 1488 KSPDATNIVEVSSETTIEKTETTMTTEMTHESEESRTSVKKEKTPEKVDEKPKSPTKKDK 1547
Query: 262 VALVTSDEKIVNPRDHLVPLKSIPGFVLEQQTQP-----GPVIPVCPNSASLIGQSQTIP 316
+ E+I +P V + P V E+ P P P P S +
Sbjct: 1548 SPEKSITEEIKSP----VKKEKSPEKVEEKPASPTKKEKSPEKPASPTKKS----ENEVK 1599
Query: 317 VVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLA 376
++K ++S + ++K + S P+K + +P K+ E+ + K P T
Sbjct: 1600 SPTKKEKSPEKSVVEELKSPKEKS-PEKADDKPKSPTKKEKSPEKSATEDVKSP-TKKEK 1657
Query: 377 SNCHIDQAIPS----DSNPAVPTNPEHKTPKKWKKR---AKKKNVLLSEGGKSNEHNG-Q 428
S +++ S +S+P T+ E K+P K +K ++K ++ KS E + +
Sbjct: 1658 SPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVE 1717
Query: 429 PTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNE 488
++P +KS PT P K K + + KS E
Sbjct: 1718 EVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPE----------KSAE 1767
Query: 489 QPTETPVQKSVNPIKAPSID---PTLPTDQPVPID----LATPKHSEGKMSKAQRRKKNK 541
+ ++P +K +P+K + PT P ++ T K + S A+ K
Sbjct: 1768 EKPKSPTKKESSPVKMADDEVKSPTKKEKSPEKVEEKPASPTKKEKTPEKSAAEELKSPT 1827
Query: 542 RALKSAWSESVHHSSDQNAKTPVQRTESLK 571
+ KS S + + K+P + E K
Sbjct: 1828 KKEKSPSSPTKKTGDESKEKSPEKPEEKPK 1857
Score = 49.3 bits (116), Expect = 3e-05
Identities = 97/514 (18%), Positives = 176/514 (33%), Gaps = 52/514 (10%)
Query: 77 TPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQ 136
TPK + + E + R K KKE E E P + + + P +
Sbjct: 1350 TPKRRVSFAEEELPKEVIDSDRKKKKSPSPDKKEKSPEKTEEKPASPTKKTGEEVKSPKE 1409
Query: 137 LCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLG 196
KK K A E+ + + + E P P V + P
Sbjct: 1410 KSPASPTKKEKS----PAAEEVKSPTKKEKSPSSPTKKEKSPSSPTKKTGDEVKEKSP-- 1463
Query: 197 LAIPIDPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKNKGENLTP-----TDENE 251
P P K K E E + P + + E + T T E+E
Sbjct: 1464 ---PKSPTKKEKSPEKPEDVKSPVKKEKSPDATNIVEVSSETTIEKTETTMTTEMTHESE 1520
Query: 252 LDRRNRREELVALVTSDEKIVNP-RDHLVPLKSIPGFV---LEQQTQPGPV--IPVCPNS 305
R + ++E DEK +P + P KSI + ++++ P V P P
Sbjct: 1521 ESRTSVKKEKTP-EKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKPASPTK 1579
Query: 306 ASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRM--------NSMPDKHNTEPPETKKRVL 357
+ P +E ++ ++ K K + P+K + +P K+
Sbjct: 1580 KEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKSPTKKEK 1639
Query: 358 DREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKKWKKRAKKKNVLLS 417
E+ + K P + + P PT E KK K +
Sbjct: 1640 SPEKSATEDVKSPTKKEKSPE-------KVEEKPTSPTKKESSPTKKTDDEVKSP----T 1688
Query: 418 EGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLPTDQPVPIDLATPKHSEGKMSNAQRNN 477
+ KS + + +P +K SP + + P ++ +P+ +E K + +
Sbjct: 1689 KKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEK-------SPEKAEEKPKSPTKKE 1741
Query: 478 VLLSEGVKSNEQPTETPVQKSVNPIKAPSIDPTLPT-DQPVPIDLATPK-HSEGKMSKAQ 535
KS + ++P +K +P K+ P PT + P+ +A + S K K+
Sbjct: 1742 ---KSPEKSAAEEVKSPTKKEKSPEKSAEEKPKSPTKKESSPVKMADDEVKSPTKKEKSP 1798
Query: 536 RRKKNKRALKSAWSESVHHSSDQNAKTPVQRTES 569
+ + K A + ++ S+ + K+P ++ +S
Sbjct: 1799 EKVEEKPASPTKKEKTPEKSAAEELKSPTKKEKS 1832
Score = 48.9 bits (115), Expect = 4e-05
Identities = 98/460 (21%), Positives = 169/460 (36%), Gaps = 91/460 (19%)
Query: 174 PEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKN-----RKEAEPNESNAEHPRACPEPPL 228
P+ K K P TE P G + EK+ +KE P + P + P
Sbjct: 1379 PDKKEKSPEKTEEKPASPTKKTGEEVKSPKEKSPASPTKKEKSPAAEEVKSPTKKEKSPS 1438
Query: 229 GLAIPIDPEKNKGENLTPTDE--NELDRRNRREELVALVTSDEKIVNPRDHLVPLKSIPG 286
P K + +PT + +E+ ++ + S EK P D P+K
Sbjct: 1439 S------PTKKEKSPSSPTKKTGDEVKEKSPPKSPTKKEKSPEK---PEDVKSPVK---- 1485
Query: 287 FVLEQQTQPGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRK---------- 336
++ P V +S + I +++T + + ++ SR S K K
Sbjct: 1486 ----KEKSPDATNIVEVSSETTIEKTETTMTTEMTHE-SEESRTSVKKEKTPEKVDEKPK 1540
Query: 337 ---RMNSMPDKHNTEPPETKKRVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAV 393
+ + P+K TE E K V + P K K AS +++ ++P
Sbjct: 1541 SPTKKDKSPEKSITE--EIKSPVKKEKSPEKVEEKP------ASPTKKEKSPEKPASPTK 1592
Query: 394 PTNPEHKTPKKWKKRAKKKNV--LLSEGGKSNEHNGQPTETPVQKSVSPINAPSIDPTLP 451
+ E K+P K +K +K V L S KS E ++P +K SP + + D P
Sbjct: 1593 KSENEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKSPTKKEKSPEKSATEDVKSP 1652
Query: 452 TDQPVPIDLATPKHSEGKMSNAQRNNVLLSEGVKSNEQPTETPVQKSVNP--IKAPSIDP 509
T + +P+ E K ++ + S K + ++P +K +P ++ P
Sbjct: 1653 TKKE-----KSPEKVEEKPTSPTKKE---SSPTKKTDDEVKSPTKKEKSPQTVEEKPASP 1704
Query: 510 TLPTDQP---VPIDLATPKHSEGKMSKAQRR---KKNKRALKSAWSE------------- 550
T P V ++ +PK + ++ + + KK K KSA E
Sbjct: 1705 TKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPEK 1764
Query: 551 --------------SVHHSSDQNAKTPVQRTESLKLVEAK 576
S +D K+P ++ +S + VE K
Sbjct: 1765 SAEEKPKSPTKKESSPVKMADDEVKSPTKKEKSPEKVEEK 1804
Score = 45.1 bits (105), Expect = 5e-04
Identities = 101/464 (21%), Positives = 157/464 (33%), Gaps = 89/464 (19%)
Query: 12 SKKRRREEKPEPLPSP-------------EQDQEQSCSKKKRRKKKKIKEEGIESHEH-D 57
+KK + EKPE + SP E E + K + ++ E ES
Sbjct: 1468 TKKEKSPEKPEDVKSPVKKEKSPDATNIVEVSSETTIEKTETTMTTEMTHESEESRTSVK 1527
Query: 58 QVLLPEPVVVATAIPITLETPKEQGAE-PIEATVVHPVPDQRPAKTHRKKKKKETVLEPQ 116
+ PE V P T K++ E I + PV ++ + +K T E
Sbjct: 1528 KEKTPEKVDEKPKSP----TKKDKSPEKSITEEIKSPVKKEKSPEKVEEKPASPTKKEKS 1583
Query: 117 PEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEP 176
PE P + S + PT KK K E + V EL + P + +
Sbjct: 1584 PEKPASPTKKSENEVKSPT--------KKEKSPEKS-VVEEL-----KSPKEKSPEKADD 1629
Query: 177 KPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAE-HPRACPEPPLGLAIPID 235
KPK P E PEK+ E + + E P E P
Sbjct: 1630 KPKSPTKKEK---------------SPEKSATEDVKSPTKKEKSPEKVEEK------PTS 1668
Query: 236 PEKNKGENLTPTDENELDRRNRREELVALVTSDEKIVNP-RDHLVPLKSIPGFVLEQQTQ 294
P K + TD+ E+ ++E+ + T +EK +P + P KS+ V + +
Sbjct: 1669 PTKKESSPTKKTDD-EVKSPTKKEK--SPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEK 1725
Query: 295 PGPVIPVCPNSASLIGQSQTIPVVDTEQKINKRSRMSKMKRKRMNSMPDKHNTEPPETKK 354
P S + + + P +++ ++ K K P + K
Sbjct: 1726 SPEKAEEKPKSPT---KKEKSPEKSAAEEVKSPTKKEKSPEKSAEEKPKSPTKKESSPVK 1782
Query: 355 RVLDREEPNKCNAKLPETLMLASNCHIDQAIPSDSNPAVPTNPEHKTPKK---------W 405
D + K PE + + PA PT E KTP+K
Sbjct: 1783 MADDEVKSPTKKEKSPEKV--------------EEKPASPTKKE-KTPEKSAAEELKSPT 1827
Query: 406 KKRAKKKNVLLSEGGKSNEHNGQ-PTETPVQKSVSPINAPSIDP 448
KK + G +S E + + P E P KS +P +P P
Sbjct: 1828 KKEKSPSSPTKKTGDESKEKSPEKPEEKP--KSPTPKKSPPGSP 1869
Score = 35.8 bits (81), Expect = 0.32
Identities = 35/132 (26%), Positives = 52/132 (38%), Gaps = 21/132 (15%)
Query: 12 SKKRRREEKP------EPLPSPEQDQEQSCSKKKRRKKKKI---------KEEGIESHEH 56
S ++ EEKP E P D E KK + +K+ KE+ E
Sbjct: 1761 SPEKSAEEKPKSPTKKESSPVKMADDEVKSPTKKEKSPEKVEEKPASPTKKEKTPEKSAA 1820
Query: 57 DQVLLPEPVVVATAIPI--TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLE 114
+++ P + + P T + KE+ E E P P + P + +KKK K
Sbjct: 1821 EELKSPTKKEKSPSSPTKKTGDESKEKSPEKPEEKPKSPTPKKSPPGSPKKKKSK----S 1876
Query: 115 PQPEPEPEPKET 126
P+ E P PK T
Sbjct: 1877 PEAEKPPAPKLT 1888
>HRX_MOUSE (P55200) Zinc finger protein HRX (ALL-1) (Fragment)
Length = 3866
Score = 51.2 bits (121), Expect = 7e-06
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 46/219 (21%)
Query: 14 KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP-EPVVVATAIP 72
K R+ + + +PS Q+Q+ + KK+ KK K E+ ES E V P EP A P
Sbjct: 1087 KMRKCQNLQWMPSKASLQKQTKAVKKKEKKSKTTEKK-ESKESTSVKSPLEPAQKAAPPP 1145
Query: 73 ITLETPKEQGAEPIEATVVH------------PVPDQRPAKTHRKKKKKETVLEPQPEPE 120
PK+ +EP V P P+ + +K + V +P
Sbjct: 1146 REEPAPKKSSSEPPPRKPVEEKSEEGGAPAPAPAPEPKQVSAPASRKSSKQVSQPAAVVP 1205
Query: 121 PEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPKE 180
P+P T+ P + S KKK +PP PEP P++
Sbjct: 1206 PQPPSTAPQKKEAPKAVPSEPKKK-------------------QPPP------PEPGPEQ 1240
Query: 181 PCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNESNAEH 219
++ +V P P +IP+ + KE P S E+
Sbjct: 1241 ---SKQKKVAPLP----SIPVKQKPKDKEKPPPVSKQEN 1272
Score = 33.1 bits (74), Expect = 2.1
Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 10/119 (8%)
Query: 14 KRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPI 73
+ + EE P P+P + +Q + R+ K++ + V+ P+P A P
Sbjct: 1165 EEKSEEGGAPAPAPAPEPKQVSAPASRKSSKQVSQPAA-------VVPPQPPSTA---PQ 1214
Query: 74 TLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHS 132
E PK +EP + P P +K + ++ +P+ + +P S +++
Sbjct: 1215 KKEAPKAVPSEPKKKQPPPPEPGPEQSKQKKVAPLPSIPVKQKPKDKEKPPPVSKQENA 1273
>SPKC_SYNY3 (P74745) Serine/threonine-protein kinase C (EC 2.7.1.37)
Length = 535
Score = 50.1 bits (118), Expect = 2e-05
Identities = 49/170 (28%), Positives = 67/170 (38%), Gaps = 27/170 (15%)
Query: 84 EPIEATVVHPVPDQRPAKT-HRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKK 142
EP E T + P+P P T P PEP P P + T S PT+ ++
Sbjct: 379 EPTEETPI-PLPSLEPRPNLFETPSPIPTPATPSPEPTPSPSPSPETT-SSPTE-DTITP 435
Query: 143 KKKRKGAESNEAVAE-----LATVCTEP-PAVQGGVLPEPKPK-----EPCSTEHPRVCP 191
+ + + E T+ +P P + V P P PK P T P++ P
Sbjct: 436 MEPEPSLDEPAPIPEPKPSPSPTISPQPSPTISIPVTPAPVPKPSPSPTPKPTVPPQISP 495
Query: 192 EPPLGLAIPI--DPEKNRKEAEPNESNAEHPRACPEPPLGLAIPIDPEKN 239
P +P+ PE E EPN P PP+G PIDPE+N
Sbjct: 496 TPQPSNTVPVIPPPENPSAETEPN---------LPAPPVG-EKPIDPEQN 535
Score = 31.6 bits (70), Expect = 6.0
Identities = 20/85 (23%), Positives = 33/85 (38%), Gaps = 3/85 (3%)
Query: 165 PPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEP--NESNAEHPRA 222
P + P P+P P + P P P++PE + E P + P
Sbjct: 401 PSPIPTPATPSPEPT-PSPSPSPETTSSPTEDTITPMEPEPSLDEPAPIPEPKPSPSPTI 459
Query: 223 CPEPPLGLAIPIDPEKNKGENLTPT 247
P+P ++IP+ P + +PT
Sbjct: 460 SPQPSPTISIPVTPAPVPKPSPSPT 484
>IF2_BORPE (Q7VYR2) Translation initiation factor IF-2
Length = 997
Score = 49.7 bits (117), Expect = 2e-05
Identities = 56/238 (23%), Positives = 91/238 (37%), Gaps = 16/238 (6%)
Query: 13 KKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVATAIP 72
+K+R K +P E EQ+ ++ + + + E + + + EP V A P
Sbjct: 89 RKKRVFVKRDPA---ELAAEQAAARAEEAAAEAVPAEAAPAPA--EPVRAEPAVETAAKP 143
Query: 73 ITLETP-KEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPEPKET---SN 128
+ E P E AEP+ A P P+Q + + EP+P+PEP+P+ +
Sbjct: 144 V--EPPVAEAPAEPVAAPAAEPQPEQPAQAEAQPEPTPAAQAEPEPQPEPQPEAAPAQAV 201
Query: 129 TDHSEPTQLCSVKKKKKRKGAESNEAVAELATVCTEPPAVQGGVLPEPKPK----EPCST 184
+ EP + SV + + + A+ P V P PK EP +
Sbjct: 202 AEPVEPAKNVSVTETEAEQARPEPVVHAQTELTSQTPTPVAQPSAPAESPKSVKAEPAAA 261
Query: 185 EHPRVCPEPPLGLAIPIDPEKNRKEA-EPNESNAEHPRACPEPPLGLAIPIDPEKNKG 241
P A P P++ R+EA E+ A R P + +PE G
Sbjct: 262 PKTTAKPGEIRRAAAPAAPDRAREEARRAAEAEAAALREMLSRPRKVLRAPEPEPQAG 319
Score = 37.4 bits (85), Expect = 0.11
Identities = 46/185 (24%), Positives = 68/185 (35%), Gaps = 40/185 (21%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVA-------TAIPIT 74
EP P PE E + ++ + K + E +Q PEPVV A T P+
Sbjct: 184 EPEPQPEPQPEAAPAQAVAEPVEPAKNVSVTETEAEQAR-PEPVVHAQTELTSQTPTPVA 242
Query: 75 -----LETPKEQGAEPIEATVVHPVPDQ-----RPAKTHRKKKKKETVLEPQ-------- 116
E+PK AEP A P + PA R +++ E +
Sbjct: 243 QPSAPAESPKSVKAEPAAAPKTTAKPGEIRRAAAPAAPDRAREEARRAAEAEAAALREML 302
Query: 117 ---------PEPEPEPKETSNTDH---SEPTQLCSVKKKKK--RKGAESNEAVAELATVC 162
PEPEP+ S T H +P + KK K GA+ AE+++
Sbjct: 303 SRPRKVLRAPEPEPQAGALSGTLHKPAGKPATTAAPKKDAKPGAPGAKKTIKTAEVSSTW 362
Query: 163 TEPPA 167
++ A
Sbjct: 363 SDDSA 367
>IF2_BORPA (Q7W9A5) Translation initiation factor IF-2
Length = 969
Score = 49.7 bits (117), Expect = 2e-05
Identities = 52/211 (24%), Positives = 80/211 (37%), Gaps = 17/211 (8%)
Query: 40 RRKKKKIKEEGIESHEHDQVLLPEPVVVATAIPITLETP-KEQGAEPIEATVVHPVPDQR 98
R+K+ +K + E + EP V A P+ E P E AEP+ A P P+Q
Sbjct: 89 RKKRVFVKRDPAEP------VRAEPAVETAAKPV--EPPVAEAPAEPVAAPAAEPQPEQP 140
Query: 99 PAKTHRKKKKKETVLEPQPEPEPEPKET---SNTDHSEPTQLCSVKKKKKRKGAESNEAV 155
+ + EP+P+PEP+P+ + + EP + SV + + +
Sbjct: 141 AQAEAQPEPTPAAQAEPEPQPEPQPEAAPAQAVAEPVEPAKNVSVTETEAEQARPEPVVH 200
Query: 156 AELATVCTEPPAVQGGVLPEPKPK----EPCSTEHPRVCPEPPLGLAIPIDPEKNRKEA- 210
A+ P V P PK EP + P A P P++ R+EA
Sbjct: 201 AQTELTSQTPAPVAQPSAPAESPKSAKAEPAAAPKTTAKPGEIRRAAAPAAPDRAREEAR 260
Query: 211 EPNESNAEHPRACPEPPLGLAIPIDPEKNKG 241
E+ A R P + +PE G
Sbjct: 261 RAAEAEAAALREMLSRPRKVLRAPEPEPQAG 291
Score = 37.7 bits (86), Expect = 0.084
Identities = 46/185 (24%), Positives = 68/185 (35%), Gaps = 40/185 (21%)
Query: 22 EPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVVA-------TAIPIT 74
EP P PE E + ++ + K + E +Q PEPVV A T P+
Sbjct: 156 EPEPQPEPQPEAAPAQAVAEPVEPAKNVSVTETEAEQA-RPEPVVHAQTELTSQTPAPVA 214
Query: 75 -----LETPKEQGAEPIEATVVHPVPDQ-----RPAKTHRKKKKKETVLEPQ-------- 116
E+PK AEP A P + PA R +++ E +
Sbjct: 215 QPSAPAESPKSAKAEPAAAPKTTAKPGEIRRAAAPAAPDRAREEARRAAEAEAAALREML 274
Query: 117 ---------PEPEPEPKETSNTDH---SEPTQLCSVKKKKK--RKGAESNEAVAELATVC 162
PEPEP+ S T H +P + KK K GA+ AE+++
Sbjct: 275 SRPRKVLRAPEPEPQAGALSGTLHKPAGKPATTAAPKKDAKPGAPGAKKTIKTAEVSSTW 334
Query: 163 TEPPA 167
++ A
Sbjct: 335 SDDSA 339
>HS1_HUMAN (P14317) Hematopoietic lineage cell specific protein
(Hematopoietic cell-specific LYN substrate 1) (LckBP1)
Length = 486
Score = 48.9 bits (115), Expect = 4e-05
Identities = 37/157 (23%), Positives = 71/157 (44%), Gaps = 20/157 (12%)
Query: 8 ELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLPEPVVV 67
E + +KR+REE+ + + QE +K K+ + + + E V P P +
Sbjct: 243 ESMAEEKRKREEEEKAQQVARRQQE----RKAVTKRSPEAPQPVIAMEEPAVPAPLPKKI 298
Query: 68 ATAIPITLETPKEQGAEPIEATVVHPVP------------DQRPAKTHRKKK----KKET 111
++ + TP +EP+ + HPVP ++ PA R + ++E
Sbjct: 299 SSEAWPPVGTPPSSESEPVRTSREHPVPLLPIRQTLPEDNEEPPALPPRTLEGLQVEEEP 358
Query: 112 VLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKG 148
V E +PEPEPEP+ D+ + ++ +++ + +G
Sbjct: 359 VYEAEPEPEPEPEPEPENDYEDVEEMDRHEQEDEPEG 395
>Y046_UREPA (Q9PR99) Hypothetical protein UU046
Length = 791
Score = 48.1 bits (113), Expect = 6e-05
Identities = 35/126 (27%), Positives = 53/126 (41%), Gaps = 17/126 (13%)
Query: 3 SHSQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEHDQVLLP 62
S + L K + + KPEP P+P D + KK+ KK +IK E + E + P
Sbjct: 65 SIKDNNLKEIPKPKPQPKPEPQPTPFPDPIPTPPKKEELKKPEIKPEEPKKPE----IKP 120
Query: 63 EPVVVATAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPEPE 122
EP+ PI TP + E P P + K P+P+P+P+
Sbjct: 121 EPIPKPKPQPIPQPTPPVETKPKEELLPPSPPPPKEEPK-------------PEPDPQPQ 167
Query: 123 PKETSN 128
P++ N
Sbjct: 168 PQQIPN 173
Score = 39.3 bits (90), Expect = 0.029
Identities = 32/129 (24%), Positives = 56/129 (42%), Gaps = 14/129 (10%)
Query: 96 DQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKKKKKRKGAESNEAV 155
D + A+ K + + +P+P+P+PEP+ T P + + KK++ K E
Sbjct: 58 DYQKARPSIKDNNLKEIPKPKPQPKPEPQPT-----PFPDPIPTPPKKEELKKPEIKPEE 112
Query: 156 AELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEPNES 215
+ + EP +P+PKP +P P V +P L +P P ++E +P
Sbjct: 113 PKKPEIKPEP-------IPKPKP-QPIPQPTPPVETKPKEEL-LPPSPPPPKEEPKPEPD 163
Query: 216 NAEHPRACP 224
P+ P
Sbjct: 164 PQPQPQQIP 172
>RRP1_DROME (P27864) Recombination repair protein 1 (DNA-(apurinic
or apyrimidinic site) lyase) (EC 4.2.99.18)
Length = 679
Score = 48.1 bits (113), Expect = 6e-05
Identities = 57/246 (23%), Positives = 90/246 (36%), Gaps = 35/246 (14%)
Query: 8 ELLHSKKRRREEKPEPLPSPEQ-----------DQEQSCSKKKRRKKKKIK-------EE 49
+L K + K EP P+P++ ++ + ++ K RK+K++ EE
Sbjct: 117 DLPAGKATKPRAKKEPTPAPDEVTSSPPKGRAKAEKPTNAQAKGRKRKELPAEANGGAEE 176
Query: 50 GIESHEHDQVLLPEPVVVATAIPITLETPKEQGAEP---------------IEATVVHPV 94
E + P + A P T+ K Q AE I A + P
Sbjct: 177 AAEPPKQRARKEAVPTLKEQAEPGTISKEKVQKAETAAKRARGTKRLADSEIAAALDEPE 236
Query: 95 PDQRPAKTHRKKKKKETVLEPQPEPEPEPKETSNTDHSEPTQLCSVKK--KKKRKGAESN 152
D+ P K K+ KK ++EP PE + + S P + KK KK G +
Sbjct: 237 VDEVPPKAASKRAKKGKMVEPSPETVGDFQSVQEEVESPPKTAAAPKKRAKKTTNGETAV 296
Query: 153 EAVAELATVCTEPPAVQGGVLPEPKPKEPCSTEHPRVCPEPPLGLAIPIDPEKNRKEAEP 212
E + T+ A + G P P K+ S + E + P K RK+A
Sbjct: 297 ELEPKTKAKPTKQRAKKEGKEPAPGKKQKKSADKENGVVEEEAKPSTETKPAKGRKKAPV 356
Query: 213 NESNAE 218
+ E
Sbjct: 357 KAEDVE 362
>YKF4_YEAST (P35732) Hypothetical 84.0 kDa protein in NUP120-CSE4
intergenic region
Length = 738
Score = 47.8 bits (112), Expect = 8e-05
Identities = 53/255 (20%), Positives = 108/255 (41%), Gaps = 43/255 (16%)
Query: 5 SQSELLHSKKRRREEKPEPLPSPEQDQEQSCSKKKRRKKKKIKEEGIESHEH-DQVLLPE 63
+ +E L ++ ++ +EK + EQ Q++ + K+ K+ I++ + S + + +
Sbjct: 181 NNNEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHKQ--IEQPSLSSKKTTSRTSASQ 238
Query: 64 P-----VVVATAIPITL---ETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEP 115
P +AT P + E+P E AE + DQ+ + K ++ET +
Sbjct: 239 PKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIKKDDQKSEASEEKVNEQETSAQE 298
Query: 116 QPEPEPEPKETSNTDH-----SEPTQLCSVKKKKKRKGAESNEAV--------------- 155
Q E EP E N D E Q + KK++ ++ ++ E +
Sbjct: 299 QEEETAEPSE-ENEDRVPEVDGEEVQEEAEKKEQVKEEEQTAEELEQEQDNVAAPEEEVT 357
Query: 156 -----AELATVCTEPPAVQGGVLPEP-----KPKEPCSTEHPRVCPEPPLGLAIPIDPEK 205
E++ V +EPP Q +P+P +P++P + P+ P+ P P P++
Sbjct: 358 VVEEKVEISAVISEPPEDQANTVPQPQQQSQQPQQPQQPQQPQQ-PQQPQQQQQPQQPQQ 416
Query: 206 NRKEAEPNESNAEHP 220
+++ + + + P
Sbjct: 417 PQQQLQQQQQQQQQP 431
Score = 35.4 bits (80), Expect = 0.42
Identities = 36/202 (17%), Positives = 79/202 (38%), Gaps = 25/202 (12%)
Query: 12 SKKRRREEKPEPLPS-----PEQDQEQSCSKKKRRKKKKIKEEGIES--HEHDQVLLPEP 64
S + + EE EP PE D E+ + +++++ K +E+ E E D V PE
Sbjct: 295 SAQEQEEETAEPSEENEDRVPEVDGEEVQEEAEKKEQVKEEEQTAEELEQEQDNVAAPEE 354
Query: 65 VVVA----TAIPITLETPKEQGAEPIEATVVHPVPDQRPAKTHRKKKKKETVLEPQPEPE 120
V I + P E A + Q+P + + ++ ++ + QP+
Sbjct: 355 EVTVVEEKVEISAVISEPPEDQANTVPQPQQQSQQPQQPQQPQQPQQPQQPQQQQQPQQP 414
Query: 121 PEPKETSNTDHSEPTQLCSVK--------------KKKKRKGAESNEAVAELATVCTEPP 166
+P++ + Q + ++++++ A+ + + +
Sbjct: 415 QQPQQQLQQQQQQQQQPVQAQAQAQEEQLSQNYYTQQQQQQYAQQQHQLQQQYLSQQQQY 474
Query: 167 AVQGGVLPEPKPKEPCSTEHPR 188
A Q P+P+ ++P S + P+
Sbjct: 475 AQQQQQHPQPQSQQPQSQQSPQ 496
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.306 0.126 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,557,381
Number of Sequences: 164201
Number of extensions: 3952036
Number of successful extensions: 16587
Number of sequences better than 10.0: 614
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 553
Number of HSP's that attempted gapping in prelim test: 13087
Number of HSP's gapped (non-prelim): 2356
length of query: 586
length of database: 59,974,054
effective HSP length: 116
effective length of query: 470
effective length of database: 40,926,738
effective search space: 19235566860
effective search space used: 19235566860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 69 (31.2 bits)
Lotus: description of TM0148.5