BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0146.2
         (687 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

VML1_HUMAN (Q8NFU1) Bestrophin 2 (Vitelliform macular dystrophy ...    34  1.5
VML2_HUMAN (Q8NFU0) Bestrophin 3 (Vitelliform macular dystrophy ...    33  2.5
SYE1_COXBU (Q83EV3) Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Gl...    33  3.3
VML1_MOUSE (Q8BGM5) Bestrophin 2 (Vitelliform macular dystrophy ...    32  4.3
SPCN_CHICK (P07751) Spectrin alpha chain, brain (Spectrin, non-e...    32  7.3

>VML1_HUMAN (Q8NFU1) Bestrophin 2 (Vitelliform macular dystrophy
           2-like protein 1)
          Length = 509

 Score = 33.9 bits (76), Expect = 1.5
 Identities = 17/52 (32%), Positives = 26/52 (49%), Gaps = 4/52 (7%)

Query: 470 FDKTVQFYNKKLLNLSPFTYAPSYYATNAFKAWWSEYWAQISKPLVDCLQCM 521
           F+K V  Y  +  +L P ++   +Y T     WWS+Y   +  PL D L C+
Sbjct: 62  FEKLV-IYCDQYASLIPVSFVLGFYVTLVVNRWWSQY---LCMPLPDALMCV 109


>VML2_HUMAN (Q8NFU0) Bestrophin 3 (Vitelliform macular dystrophy
           2-like protein 2)
          Length = 473

 Score = 33.1 bits (74), Expect = 2.5
 Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 3/48 (6%)

Query: 477 YNKKLLNLSPFTYAPSYYATNAFKAWWSEYWAQISKPLVDCLQCMTDA 524
           Y  +  +L P ++   +Y T     WWS+Y    S PL D L C+  A
Sbjct: 68  YCNRSADLIPLSFVLGFYVTLVVNRWWSQY---TSIPLPDQLMCVISA 112


>SYE1_COXBU (Q83EV3) Glutamyl-tRNA synthetase 1 (EC 6.1.1.17)
           (Glutamate--tRNA ligase 1) (GluRS 1)
          Length = 469

 Score = 32.7 bits (73), Expect = 3.3
 Identities = 25/97 (25%), Positives = 47/97 (47%), Gaps = 12/97 (12%)

Query: 120 YLKWLDRVEGDKKQHWKD--VGIFDLIQLSRSPISYNPAMLLSALYFWERSTNCLHVPFG 177
           YL  L    GD++   ++  V +FD+  +SRSP ++NP  LL     + ++         
Sbjct: 263 YLIRLGWAHGDQEIFSREEMVQLFDISAVSRSPAAFNPEKLLWLNQHYLKT--------- 313

Query: 178 MITPTLLDVAAITGLWPIGDDYHSAPAPVKPISIPTD 214
            ++PT++  A  T L   G D  + P+  + I++  +
Sbjct: 314 -VSPTIIAEAFATQLEKAGTDLRNGPSLEQVIALQAE 349


>VML1_MOUSE (Q8BGM5) Bestrophin 2 (Vitelliform macular dystrophy
           2-like protein 1)
          Length = 508

 Score = 32.3 bits (72), Expect = 4.3
 Identities = 16/52 (30%), Positives = 26/52 (49%), Gaps = 4/52 (7%)

Query: 470 FDKTVQFYNKKLLNLSPFTYAPSYYATNAFKAWWSEYWAQISKPLVDCLQCM 521
           F+K V  Y  +  +L P ++   +Y T     WW++Y   +  PL D L C+
Sbjct: 62  FEKLV-IYCDQYASLIPVSFVLGFYVTLVVHRWWNQY---LCMPLPDALMCI 109


>SPCN_CHICK (P07751) Spectrin alpha chain, brain (Spectrin,
            non-erythroid alpha chain) (Fodrin alpha chain)
          Length = 2477

 Score = 31.6 bits (70), Expect = 7.3
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 15/99 (15%)

Query: 288  LNEAVEDIRNTKTVSLNAAGPLWLFQLWLNAVFESLL-PVQDNPLTASNTRIDAHRLETL 346
            L EA E  R  + + L  A     F  W     E L  PV+ N L           ++ L
Sbjct: 2084 LLEAQEHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSL---------EEIKAL 2134

Query: 347  TPAYDA-----SSFEADFRKYFTMFLELKHYRSSFSPYS 380
              A+DA     SS +ADF +   +  ++K +R + +PY+
Sbjct: 2135 REAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYT 2173


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.321    0.136    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,045,311
Number of Sequences: 164201
Number of extensions: 3652209
Number of successful extensions: 7729
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 7728
Number of HSP's gapped (non-prelim): 6
length of query: 687
length of database: 59,974,054
effective HSP length: 117
effective length of query: 570
effective length of database: 40,762,537
effective search space: 23234646090
effective search space used: 23234646090
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)