BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0142.1
(142 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RA50_AQUAE (O67124) Probable DNA double-strand break repair rad5... 46 2e-05
ECX1_METMA (Q8PTT8) Probable exosome complex exonuclease 1 (EC 3... 46 2e-05
IF2_AQUAE (O67825) Translation initiation factor IF-2 42 3e-04
MYSP_BRUMA (Q01202) Paramyosin 42 4e-04
MYSP_DIRIM (P13392) Paramyosin (Fragment) 42 6e-04
ENAH_HUMAN (Q8N8S7) Enabled protein homolog 42 6e-04
MYSP_ONCVO (Q02171) Paramyosin 41 7e-04
BPA1_HUMAN (Q03001) Bullous pemphigoid antigen 1 isoforms 1/2/3/... 41 7e-04
TRHY_RABIT (P37709) Trichohyalin 41 0.001
RA50_PYRAB (Q9UZC8) DNA double-strand break repair rad50 ATPase 40 0.001
RA50_METKA (Q8TXI4) DNA double-strand break repair rad50 ATPase 40 0.001
TRHY_SHEEP (P22793) Trichohyalin 40 0.002
NIN_MOUSE (Q61043) Ninein 40 0.002
MYSP_CAEEL (P10567) Paramyosin 40 0.002
MYS2_DICDI (P08799) Myosin II heavy chain, non muscle 40 0.002
GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7... 40 0.002
USO1_YEAST (P25386) Intracellular protein transport protein USO1 40 0.002
CAFA_MOUSE (Q9QWF0) Chromatin assembly factor 1 subunit A (CAF-1... 40 0.002
YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome ... 39 0.003
TRHY_HUMAN (Q07283) Trichohyalin 39 0.003
>RA50_AQUAE (O67124) Probable DNA double-strand break repair rad50
ATPase
Length = 978
Score = 46.2 bits (108), Expect = 2e-05
Identities = 40/138 (28%), Positives = 64/138 (45%), Gaps = 14/138 (10%)
Query: 3 HLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE---EDLR 59
H E+ S R+ K+ + AL E + EE+ ++ +A+ R ++E D
Sbjct: 665 HFEELSSRKSKLEGELSALNE-SINSLEEERKEKLKELANIYEVAKSPREVVELYLGDKE 723
Query: 60 PELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHA 119
ELER ++EF E S LKL +K +EEKLK E I E ++K +++
Sbjct: 724 AELERKIKEF--------EESFQSLKL--KKSEIEEKLKEYEGIRELSDIKGEYESVKTQ 773
Query: 120 LERLEKDRSEQRQECRRM 137
LE K E ++E +
Sbjct: 774 LEEKHKKLGEVKRELEHL 791
Score = 36.6 bits (83), Expect = 0.018
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 9/113 (7%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQ-EL 79
L+E ++ + L L + E +R +EE LR E+ +L+E + +EE++ E
Sbjct: 515 LKEKEEREIDTTLKLYAQKINSLKEEMEKLRNEVEE-LRKEIPENLKERIKKLEELRIEK 573
Query: 80 SRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERL-EKDRSEQR 131
+LE KL K ++ LE++ K +++E + +L Q LE L EK R + R
Sbjct: 574 EKLEHKLNKYRKALEDRQK------QKEEAQAKLHKAQTELELLKEKIREKSR 620
Score = 36.6 bits (83), Expect = 0.018
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 13/137 (9%)
Query: 4 LEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELE 63
L + VR+ K+ + L++ A EE LN AE + E++ ELE
Sbjct: 290 LTELKVRKNKLTKELAVLKDELSFAQEE---LN-------RIEAEKEKFKEEKEREKELE 339
Query: 64 RDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTA-EEILERDEL-KDRLSNIQHALE 121
L++ E ++ELS+L LKEKER E+ K E++ ER E K ++ + LE
Sbjct: 340 HRLKKLQEIKEILKELSQLS-SSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKLE 398
Query: 122 RLEKDRSEQRQECRRMR 138
++++ SE+ +M+
Sbjct: 399 KIKELFSEEEYTSLKMK 415
Score = 36.2 bits (82), Expect = 0.024
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 8 SVREKKMASYIVALEELRK-KAFEEDLFLNIRHP-EGTTTIAELIR--TLLEEDLRPELE 63
S KK+ ++ LEEL K + + F N+ E EL++ T ++++ +
Sbjct: 150 SSERKKILINLLGLEELEKVRQLASETFKNLEGKREALKKEYELLKDYTPTKKEVLEKTL 209
Query: 64 RDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERL 123
++L E L ++E +E R ELK +EK+ LE +L L+ L N++ +E+L
Sbjct: 210 KNLEEELKELKETEEKLRQELKKAEEKDSLERELSQVVTKLKE------LENLEKEVEKL 263
Query: 124 EK 125
+
Sbjct: 264 RE 265
Score = 35.4 bits (80), Expect = 0.041
Identities = 37/134 (27%), Positives = 69/134 (50%), Gaps = 9/134 (6%)
Query: 9 VREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTI----AELIRTLLE-EDLRPELE 63
V EK + + L+EL++ EE L ++ E ++ ++++ L E E+L E+E
Sbjct: 204 VLEKTLKNLEEELKELKET--EEKLRQELKKAEEKDSLERELSQVVTKLKELENLEKEVE 261
Query: 64 RDLREFLAFVEEVQELSRLELKLLKEKERLEE-KLKTAEEILERDELKDRLSNIQHALER 122
+ LRE L F +V + ++ + ++L E K++ + E LKD LS Q L R
Sbjct: 262 K-LREKLEFSRKVAPYVPIAKRIEEIDKKLTELKVRKNKLTKELAVLKDELSFAQEELNR 320
Query: 123 LEKDRSEQRQECRR 136
+E ++ + ++E R
Sbjct: 321 IEAEKEKFKEEKER 334
Score = 35.0 bits (79), Expect = 0.053
Identities = 38/136 (27%), Positives = 66/136 (47%), Gaps = 16/136 (11%)
Query: 4 LEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELE 63
L++ EK++ LE RK A + I + T ++ + L ++L
Sbjct: 250 LKELENLEKEVEKLREKLEFSRKVAPYVPIAKRIEEIDKKLTELKVRKNKLTKELAV--- 306
Query: 64 RDLREFLAFVEEVQELSRLEL---KLLKEKER---LEEKLKTAEEILERDELKDRLSNIQ 117
L++ L+F +E EL+R+E K +EKER LE +LK +EI E+ LS +
Sbjct: 307 --LKDELSFAQE--ELNRIEAEKEKFKEEKEREKELEHRLKKLQEI---KEILKELSQLS 359
Query: 118 HALERLEKDRSEQRQE 133
+L+ E++ + +QE
Sbjct: 360 SSLKEKEREYEQAKQE 375
Score = 34.3 bits (77), Expect = 0.091
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 15/144 (10%)
Query: 5 EQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELER 64
E R KK+ + E+L K + L R + A+L + E +L E R
Sbjct: 557 ENLKERIKKLEELRIEKEKLEHKLNKYRKALEDRQKQKEEAQAKLHKAQTELELLKEKIR 616
Query: 65 DLREFLAFVEEVQELSRLE-----LK--------LLKEKERLEEKL-KTAEEILER-DEL 109
+ + +E+ + RLE LK L+E E E+KL K EE+ R +L
Sbjct: 617 EKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQEIEEKEKKLRKHFEELSSRKSKL 676
Query: 110 KDRLSNIQHALERLEKDRSEQRQE 133
+ LS + ++ LE++R E+ +E
Sbjct: 677 EGELSALNESINSLEEERKEKLKE 700
Score = 28.5 bits (62), Expect = 5.0
Identities = 23/59 (38%), Positives = 35/59 (58%), Gaps = 5/59 (8%)
Query: 54 LEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDR 112
++E L EL+R L+E E+ +L L K KEK+++ EK+ + LER ELK+R
Sbjct: 414 MKERLLVELQRKLKE---LKEKEGQLENLTQK-YKEKKKVHEKVLNELKELER-ELKER 467
>ECX1_METMA (Q8PTT8) Probable exosome complex exonuclease 1 (EC
3.1.13.-)
Length = 493
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/78 (37%), Positives = 41/78 (52%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLS 114
EEDL +LE DL E L EE E E + L+E+ LE L+ A E+ E DE++ RL
Sbjct: 337 EEDLEEDLEEDLGEELEEEEEELEEEEFEEEALEEETELEASLECAPELKEFDEIEARLE 396
Query: 115 NIQHALERLEKDRSEQRQ 132
++E E+ E +
Sbjct: 397 KEDASIEAEEEIEPEAEE 414
Score = 34.3 bits (77), Expect = 0.091
Identities = 27/84 (32%), Positives = 42/84 (49%), Gaps = 5/84 (5%)
Query: 47 AELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILER 106
AE++ + + D ELE ++ E L EE E E E+E LEE+ + EE LE
Sbjct: 288 AEILASEVIPDFEDELEEEIEEELEESEEDLETEEEEF----EEEALEEEAE-PEEDLEE 342
Query: 107 DELKDRLSNIQHALERLEKDRSEQ 130
D +D ++ E LE++ E+
Sbjct: 343 DLEEDLGEELEEEEEELEEEEFEE 366
Score = 32.0 bits (71), Expect = 0.45
Identities = 29/117 (24%), Positives = 52/117 (43%), Gaps = 9/117 (7%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIA-------ELIRTLLEEDLRPELERDLREFL--AF 72
EEL ++ FEE+ E + A E+ L +ED E E ++ A
Sbjct: 357 EELEEEEFEEEALEEETELEASLECAPELKEFDEIEARLEKEDASIEAEEEIEPEAEEAT 416
Query: 73 VEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSE 129
E ++E + +E E+E +E + + EE E ++ + + A E E+++SE
Sbjct: 417 EEGLEEEAEIEETAASEEENIEAEAEAEEEAEPEVEAEEISTEAEEAEEEPEEEKSE 473
Score = 30.0 bits (66), Expect = 1.7
Identities = 24/86 (27%), Positives = 39/86 (44%), Gaps = 5/86 (5%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERD 107
E+ +L ++ P+ E +L E E +EL E L E+E EE+ E E D
Sbjct: 285 EVEAEILASEVIPDFEDELEE-----EIEEELEESEEDLETEEEEFEEEALEEEAEPEED 339
Query: 108 ELKDRLSNIQHALERLEKDRSEQRQE 133
+D ++ LE E++ E+ E
Sbjct: 340 LEEDLEEDLGEELEEEEEELEEEEFE 365
Score = 27.7 bits (60), Expect = 8.5
Identities = 29/109 (26%), Positives = 44/109 (39%), Gaps = 11/109 (10%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
EE ++ EEDL + E E LEE E +L L E++E
Sbjct: 337 EEDLEEDLEEDLGEELEEEEEELEEEEFEEEALEE------ETELEASLECAPELKEFDE 390
Query: 82 LELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQ 130
+E +L KE +E AEE +E + + ++ E E SE+
Sbjct: 391 IEARLEKEDASIE-----AEEEIEPEAEEATEEGLEEEAEIEETAASEE 434
>IF2_AQUAE (O67825) Translation initiation factor IF-2
Length = 805
Score = 42.4 bits (98), Expect = 3e-04
Identities = 39/136 (28%), Positives = 74/136 (53%), Gaps = 17/136 (12%)
Query: 9 VREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE----EDLRPELER 64
V EKK V +EE+ +K EE+ + ++ ELI+ +LE E + ++E+
Sbjct: 97 VEEKKPE---VIVEEIEEKKEEEE---KKEEEKPKKSVEELIKEILEKKEKEKEKKKVEK 150
Query: 65 DLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLE 124
+ +E V EV++ R E K KE+++ EEK K ER+ ++ ++HA+E+ E
Sbjct: 151 ERKEEKVRVVEVKKEERKEEK--KEEKKEEEKPKIKMSKKEREIMR----KLEHAVEK-E 203
Query: 125 KDRSEQRQECRRMRRD 140
K + E+R++ ++ + +
Sbjct: 204 KKKQEKREKEKKKKEE 219
Score = 29.3 bits (64), Expect = 2.9
Identities = 25/102 (24%), Positives = 48/102 (46%), Gaps = 24/102 (23%)
Query: 46 IAELIR----TLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAE 101
IAEL++ + + + PE+ ++ E ++ EV+ KE+E LEE+ E
Sbjct: 247 IAELMKRGVLATINQPVPPEVAVEVAESFGYLAEVK----------KEEEELEEEALLKE 296
Query: 102 EILERDELKDR------LSNIQHA----LERLEKDRSEQRQE 133
E +EL+ R + ++ H L+R+ K +R++
Sbjct: 297 EEEREEELQPRPPIVVVMGHVDHGKTTLLDRIRKTNVAEREK 338
>MYSP_BRUMA (Q01202) Paramyosin
Length = 880
Score = 42.0 bits (97), Expect = 4e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 1 ASHLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE----- 55
A + EQ + +K++ A L+ + E L +++ + T I E + LE
Sbjct: 330 AEYEEQIEIMLQKISQLEKAKSRLQSEV--EVLIVDLEKAQNTIAILERAKEQLEKTVNE 387
Query: 56 -----EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
++L ELE RE A + E+Q+L L K +++KE L + K ++ L E K
Sbjct: 388 LKVRIDELTVELEAAQREARAALAELQKLKNLYEKAVEQKEALARENKKLQDDLH--EAK 445
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMR 138
+ L++ L L+ + + E R ++
Sbjct: 446 EALADANRKLHELDLENARLAGEIRELQ 473
Score = 28.5 bits (62), Expect = 5.0
Identities = 19/84 (22%), Positives = 43/84 (50%), Gaps = 2/84 (2%)
Query: 50 IRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDEL 109
+RT L+E+ E + + LA E Q S+ + ++ E +E+ K + + ++ E
Sbjct: 275 VRTALDEESAARAEAEHKLALANTEITQWKSKFDAEVALHHEEVEDLRK--KMLQKQAEY 332
Query: 110 KDRLSNIQHALERLEKDRSEQRQE 133
++++ + + +LEK +S + E
Sbjct: 333 EEQIEIMLQKISQLEKAKSRLQSE 356
>MYSP_DIRIM (P13392) Paramyosin (Fragment)
Length = 848
Score = 41.6 bits (96), Expect = 6e-04
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 1 ASHLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE----- 55
A + EQ + +K++ A L+ + E L +++ + T I E + LE
Sbjct: 303 AEYEEQIEIMLQKISQLEKAKSRLQSEV--EVLIVDLEKAQNTIAILERAKEQLEKTVNE 360
Query: 56 -----EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
++L ELE RE A + E+Q++ L K +++KE L + K ++ L E K
Sbjct: 361 LKVRIDELTVELEAAQREARAALAELQKMKNLYEKAIEQKEALARENKKLQDDLH--EAK 418
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMR 138
+ L++ L L+ + + E R ++
Sbjct: 419 EALADANRKLHELDLENARLAGEIRELQ 446
Score = 28.5 bits (62), Expect = 5.0
Identities = 19/84 (22%), Positives = 43/84 (50%), Gaps = 2/84 (2%)
Query: 50 IRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDEL 109
+RT L+E+ E + + LA E Q S+ + ++ E +E+ K + + ++ E
Sbjct: 248 VRTALDEESAARAEAEHKLALANTEITQWKSKFDAEVALHHEEVEDLRK--KMLQKQAEY 305
Query: 110 KDRLSNIQHALERLEKDRSEQRQE 133
++++ + + +LEK +S + E
Sbjct: 306 EEQIEIMLQKISQLEKAKSRLQSE 329
>ENAH_HUMAN (Q8N8S7) Enabled protein homolog
Length = 591
Score = 41.6 bits (96), Expect = 6e-04
Identities = 35/96 (36%), Positives = 51/96 (52%), Gaps = 10/96 (10%)
Query: 51 RTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKL-------KTAEEI 103
R L E+ + ELER+ E E E RLE + L E+ERLE++ + +E
Sbjct: 145 RQLQEQQRQKELERERLERERMERERLERERLERERL-ERERLEQEQLERERQERERQER 203
Query: 104 LERDELKDRLSNIQHALERLEKDRSEQRQECRRMRR 139
LER E +R ++ ERL+++R E RQE R+ R
Sbjct: 204 LERQERLERQERLERQ-ERLDRERQE-RQERERLER 237
Score = 33.9 bits (76), Expect = 0.12
Identities = 32/112 (28%), Positives = 52/112 (45%), Gaps = 7/112 (6%)
Query: 35 LNIRHPEGTTTIAELIRTLLE----EDLRPELERDLREFLAFVEEVQELSRLELKLLKEK 90
LN E A + LE ++ P L R + A V+ LE++ + +
Sbjct: 89 LNFGSKEDANVFASAMMHALEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQ 148
Query: 91 ERLEEKLKTAEEILERDEL-KDRLSNIQHALERLEKDRSEQRQ-ECRRMRRD 140
E+ +K + E LER+ + ++RL + ERLE++R EQ Q E R R+
Sbjct: 149 EQQRQK-ELERERLERERMERERLERERLERERLERERLEQEQLERERQERE 199
Score = 31.2 bits (69), Expect = 0.77
Identities = 36/122 (29%), Positives = 55/122 (44%), Gaps = 16/122 (13%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
+EL ++ E + R L R LE++ + E ER RE +E + L R
Sbjct: 154 KELERERLERERMERERLERERLERERLERERLEQE-QLERERQERERQERLERQERLER 212
Query: 82 LELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQ----ECRRM 137
+ERLE + + E ER E ++RL ++ ER E++R EQ + E R
Sbjct: 213 --------QERLERQERLDRERQERQE-RERLERLER--ERQERERQEQLEREQLEWERE 261
Query: 138 RR 139
RR
Sbjct: 262 RR 263
>MYSP_ONCVO (Q02171) Paramyosin
Length = 879
Score = 41.2 bits (95), Expect = 7e-04
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 1 ASHLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE----- 55
A + EQ + +K++ A L+ + E L +++ + T I E + LE
Sbjct: 330 AEYEEQIEIMLQKISQLEKAKSRLQSEV--EVLIVDLEKAQNTIAILERAKEQLEKTVNE 387
Query: 56 -----EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
++L ELE RE A + E+Q++ L K +++KE L + K ++ L E K
Sbjct: 388 LKVRIDELTVELEAAQREARAALAELQKMKNLYEKAVEQKEALARENKKLQDDLH--EAK 445
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMR 138
+ L++ L L+ + + E R ++
Sbjct: 446 EALADANRKLHELDLENARLAGEIRELQ 473
Score = 28.5 bits (62), Expect = 5.0
Identities = 19/84 (22%), Positives = 43/84 (50%), Gaps = 2/84 (2%)
Query: 50 IRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDEL 109
+RT L+E+ E + + LA E Q S+ + ++ E +E+ K + + ++ E
Sbjct: 275 VRTALDEESAARAEAEHKLALANTEITQWKSKFDAEVALHHEEVEDLRK--KMLQKQAEY 332
Query: 110 KDRLSNIQHALERLEKDRSEQRQE 133
++++ + + +LEK +S + E
Sbjct: 333 EEQIEIMLQKISQLEKAKSRLQSE 356
>BPA1_HUMAN (Q03001) Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8
(230 kDa bullous pemphigoid antigen) (BPA)
(Hemidesmosomal plaque protein) (Dystonia musculorum
protein) (Dystonin) (Fragment)
Length = 3214
Score = 41.2 bits (95), Expect = 7e-04
Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 16/135 (11%)
Query: 14 MASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEE--------DLRPELERD 65
M YI + K+ EE++ +N HP I EL +E DL +
Sbjct: 1638 MTQYIKFAGDSLKRLEEEEVIINSEHP---VNIKELEIKRCKETSEHGAYSDLLQRQKAT 1694
Query: 66 LREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEK 125
+ E ++ EL R+ +L K+K R+EE+L E E +EL+ + N++ L+K
Sbjct: 1695 VLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAE-NELRKQQRNVEDI--SLQK 1751
Query: 126 DRSEQRQECRRMRRD 140
R+E E ++ RR+
Sbjct: 1752 IRAE--SEAKQYRRE 1764
Score = 37.0 bits (84), Expect = 0.014
Identities = 42/145 (28%), Positives = 68/145 (45%), Gaps = 12/145 (8%)
Query: 2 SHLEQFSVREKKMASYIVALEELRK--KAFEEDLFLNIRHPEGTTTIAELIRTLLE-EDL 58
S LE+ KK S + EEL K +A E +L R+ E + + IR E +
Sbjct: 1706 SELERMVAELKKQKSRVE--EELPKVREAAENELRKQQRNVEDISL--QKIRAESEAKQY 1761
Query: 59 RPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKL-----KTAEEILERDELKDRL 113
R ELE +RE A E++ + +L ++ ++ +EE L + E R L+D L
Sbjct: 1762 RRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHL 1821
Query: 114 SNIQHALERLEKDRSEQRQECRRMR 138
+L LE+ +++ +E RR R
Sbjct: 1822 KRKDLSLNDLEQQKNKLMEELRRKR 1846
Score = 29.3 bits (64), Expect = 2.9
Identities = 21/85 (24%), Positives = 42/85 (48%), Gaps = 9/85 (10%)
Query: 56 EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRL-- 113
++L ER+ +E + + E+ + L+L ++RL +++T LERD+L + +
Sbjct: 1255 QELLKSAEREEQEESVYNLYISEVRNIRLRLENCEDRLIRQIRTP---LERDDLHESVFR 1311
Query: 114 ----SNIQHALERLEKDRSEQRQEC 134
++ LERL+ D +C
Sbjct: 1312 ITEQEKLKKELERLKDDLGTITNKC 1336
>TRHY_RABIT (P37709) Trichohyalin
Length = 1407
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/92 (31%), Positives = 50/92 (53%), Gaps = 13/92 (14%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDR-- 112
E++LR E +R LRE E Q L E + L+ +ER E KL+ E++L R+E + R
Sbjct: 901 EQELRQERDRKLRE------EEQLLQESEEERLRRQER-ERKLREEEQLLRREEQELRRE 953
Query: 113 ----LSNIQHALERLEKDRSEQRQECRRMRRD 140
L + L+ E++R +++ R++R +
Sbjct: 954 RARKLREEEQLLQEREEERLRRQERARKLREE 985
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 14/91 (15%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEIL-----ERDEL 109
E++LR E ER LRE E Q L R E +L +E+ER KL+ E++L ER
Sbjct: 641 EQELRQERERKLRE------EEQLLRREEQELRQERER---KLREEEQLLQEREEERLRR 691
Query: 110 KDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
++R ++ + L ++ E RQE R R+
Sbjct: 692 QERARKLREEEQLLRQEEQELRQERERKLRE 722
Score = 38.1 bits (87), Expect = 0.006
Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEED---------LRPELERDLREFLAF 72
+E +K EE+ L R E E R L EE+ LR E ER LRE
Sbjct: 668 QERERKLREEEQLLQEREEERLRR-QERARKLREEEQLLRQEEQELRQERERKLREEEQL 726
Query: 73 VEEVQELSRLE--LKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQ 130
+ ++L R E KL +E++ L+E + EE L R E + +L + R E+ ++
Sbjct: 727 LRREEQLLRQERDRKLREEEQLLQE---SEEERLRRQEREQQLRRERDRKFREEEQLLQE 783
Query: 131 RQECRRMRRD 140
R+E R R++
Sbjct: 784 REEERLRRQE 793
Score = 37.4 bits (85), Expect = 0.011
Identities = 40/135 (29%), Positives = 64/135 (46%), Gaps = 19/135 (14%)
Query: 5 EQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELER 64
EQ RE+++ +E +K EE+ L E L R E+ LR E +R
Sbjct: 724 EQLLRREEQLLR-----QERDRKLREEEQLLQESEEE------RLRRQEREQQLRRERDR 772
Query: 65 DLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLE 124
RE E Q L E + L+ +ER E KL+ E++L+ E ++RL + + E
Sbjct: 773 KFRE------EEQLLQEREEERLRRQER-ERKLREEEQLLQERE-EERLRRQERERKLRE 824
Query: 125 KDRSEQRQECRRMRR 139
+++ Q +E R+RR
Sbjct: 825 EEQLLQEREEERLRR 839
Score = 36.2 bits (82), Expect = 0.024
Identities = 34/123 (27%), Positives = 63/123 (50%), Gaps = 11/123 (8%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
+EL+++ EE+ R + + E LL + E R+ ++ +EE++E
Sbjct: 212 QELKRELREEEQQRRERREQHERALQEEEEQLLRQRRWREEPREQQQLRRELEEIRERE- 270
Query: 82 LELKLLKEKERLEEKLKTAEEILERDE-----LKDRLSNIQHALERLE-KDRSEQRQECR 135
+ L+++ER E++L+ E+ LE++E L+ L I+ +RLE ++R EQR E
Sbjct: 271 ---QRLEQEERREQQLR-REQRLEQEERREQQLRRELEEIREREQRLEQEERREQRLEQE 326
Query: 136 RMR 138
R
Sbjct: 327 ERR 329
Score = 36.2 bits (82), Expect = 0.024
Identities = 40/126 (31%), Positives = 63/126 (49%), Gaps = 12/126 (9%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRT---LL---EEDLRPELERDLREFLAFV-E 74
+E +K EE+ L E A +R LL E++LR E +R LRE + +
Sbjct: 840 QERERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKLREEEQLLRQ 899
Query: 75 EVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQEC 134
E QEL + + L+E+E+L ++ + EE L R E + +L + L R E+ E R+E
Sbjct: 900 EEQELRQERDRKLREEEQLLQE--SEEERLRRQERERKLREEEQLLRREEQ---ELRRER 954
Query: 135 RRMRRD 140
R R+
Sbjct: 955 ARKLRE 960
Score = 35.8 bits (81), Expect = 0.031
Identities = 37/124 (29%), Positives = 58/124 (45%), Gaps = 14/124 (11%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
E+L ++ EE L R E + E + L E+ ERD + F EE Q L
Sbjct: 1104 EQLLQEREEERL----RRQERARKLREEEQLLRREEQLLRQERDRK----FREEEQLLQE 1155
Query: 82 LELKLLKEKERLEEKLKTAEEIL-----ERDELKDRLSNIQHALERLEKDRSEQRQECRR 136
E + L+ +ER E KL+ E++L ER ++R ++ + L ++ E RQE R
Sbjct: 1156 SEEERLRRQER-ERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERAR 1214
Query: 137 MRRD 140
R+
Sbjct: 1215 KLRE 1218
Score = 35.8 bits (81), Expect = 0.031
Identities = 25/87 (28%), Positives = 49/87 (55%), Gaps = 4/87 (4%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDR-L 113
EE+L+ E R RE E ++L R E + + +ER E + + EE+ + ++L+DR L
Sbjct: 550 EEELQREKRRQERE--REYREEEKLQREEDEKRRRQER-ERQYRELEELRQEEQLRDRKL 606
Query: 114 SNIQHALERLEKDRSEQRQECRRMRRD 140
+ L+ E++R +++ R++R +
Sbjct: 607 REEEQLLQEREEERLRRQERERKLREE 633
Score = 35.4 bits (80), Expect = 0.041
Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 9/95 (9%)
Query: 55 EEDLRPELERDLREFLAFVEEVQE----LSRLELKLLKEKERL---EEKL--KTAEEILE 105
E+ LR E +R LRE ++E +E E +L +E++R EE+L + EE L
Sbjct: 731 EQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREEEQLLQEREEERLR 790
Query: 106 RDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
R E + +L + L+ E++R +++ R++R +
Sbjct: 791 RQERERKLREEEQLLQEREEERLRRQERERKLREE 825
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/88 (35%), Positives = 45/88 (50%), Gaps = 11/88 (12%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERD--ELKDR 112
E++LR E R LRE E Q L E + L+ +ER KL+ E++L R+ EL+
Sbjct: 947 EQELRRERARKLRE------EEQLLQEREEERLRRQERAR-KLREEEQLLRREEQELRQE 999
Query: 113 LSNIQHALERLEKDRSEQRQECRRMRRD 140
E+L ++R E+R RR RD
Sbjct: 1000 RDRKFREEEQLLQEREEER--LRRQERD 1025
Score = 35.4 bits (80), Expect = 0.041
Identities = 39/122 (31%), Positives = 61/122 (49%), Gaps = 15/122 (12%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEED---LRPELERDLREFLAFVEEVQE 78
E+LR+ EE+L R E E + EED R E ER RE +EE+++
Sbjct: 545 EQLRE---EEELQREKRRQEREREYREEEKLQREEDEKRRRQERERQYRE----LEELRQ 597
Query: 79 LSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRMR 138
+L + L+E+E+L ++ + EE L R E + +L + L + E+ E RQE R
Sbjct: 598 EEQLRDRKLREEEQLLQERE--EERLRRQERERKLREEEQLLRQEEQ---ELRQERERKL 652
Query: 139 RD 140
R+
Sbjct: 653 RE 654
Score = 35.0 bits (79), Expect = 0.053
Identities = 43/124 (34%), Positives = 62/124 (49%), Gaps = 19/124 (15%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLR-PELERDLREFLAFVEEVQEL 79
LEELR++ D +R E +L++ EE LR E ER LRE E Q L
Sbjct: 592 LEELRQEEQLRDR--KLREEE------QLLQEREEERLRRQERERKLRE------EEQLL 637
Query: 80 SRLELKLLKEKERL---EEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRR 136
+ E +L +E+ER EE+L EE R E + +L + L+ E++R +RQE R
Sbjct: 638 RQEEQELRQERERKLREEEQLLRREEQELRQERERKLREEEQLLQEREEERL-RRQERAR 696
Query: 137 MRRD 140
R+
Sbjct: 697 KLRE 700
Score = 35.0 bits (79), Expect = 0.053
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 19/136 (13%)
Query: 23 ELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFL--AFVEEVQELS 80
E +K EE+ L R E + EE L E++LR+ F EE Q L
Sbjct: 953 ERARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREEQELRQERDRKFREEEQLLQ 1012
Query: 81 RLELKLLKEKERLEEKLKTAEEILERDELKD----------------RLSNIQHALERLE 124
E + L+ +ER + K + E L R EL++ R + L R E
Sbjct: 1013 EREEERLRRQER-DRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQE 1071
Query: 125 KDRSEQRQECRRMRRD 140
+DR + +E +R R++
Sbjct: 1072 RDRKFREEEQQRRRQE 1087
Score = 35.0 bits (79), Expect = 0.053
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Query: 48 ELIRTLLEEDLR-PELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEIL-E 105
+L++ EE LR E ER LRE E Q L E + L+ +ER E KL+ E++L E
Sbjct: 779 QLLQEREEERLRRQERERKLRE------EEQLLQEREEERLRRQER-ERKLREEEQLLQE 831
Query: 106 RDELKDRLSNIQHALERLEKDRSEQRQECRRMR 138
R+E + R + L E+ ++ QE R+ R
Sbjct: 832 REEERLRRQERERKLREEEQLLRQEEQELRQER 864
Score = 34.7 bits (78), Expect = 0.070
Identities = 35/95 (36%), Positives = 50/95 (51%), Gaps = 7/95 (7%)
Query: 48 ELIRTLLEEDLR-PELERDLREFLAFVE-EVQELSRLELKLLKEKERLEEKLKTAEEILE 105
+L++ EE LR E ER LRE + E QEL R + L+E+E+L ++ + EE L
Sbjct: 917 QLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQERE--EERLR 974
Query: 106 RDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
R E +L + L R E+ E RQE R R+
Sbjct: 975 RQERARKLREEEQLLRREEQ---ELRQERDRKFRE 1006
Score = 34.7 bits (78), Expect = 0.070
Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLA--FVEEVQEL 79
+E +K EE+ L R E + EE L + E++LR+ A EE Q L
Sbjct: 1164 QERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERARKLREEEQLL 1223
Query: 80 SRLELKLLKEKERLEEKLKTAEEILERDEL-----KDRLSNIQHALERLEKDRSEQRQEC 134
+ E +L +E++R K + E++L R+E +DR + L + ++ +RQE
Sbjct: 1224 RQEEQELRQERDR---KFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQER 1280
Query: 135 RRMRRD 140
R R+
Sbjct: 1281 ARKLRE 1286
Score = 33.9 bits (76), Expect = 0.12
Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
Query: 54 LEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDE----- 108
LE++ R E + + L E ++ R EL+ ++E+E+ E+ + E+ LE++E
Sbjct: 273 LEQEERREQQLRREQRLEQEERREQQLRRELEEIREREQRLEQEERREQRLEQEERREQQ 332
Query: 109 LKDRLSNIQHALERLE-KDRSEQ--RQECRRMRRD 140
LK L I+ +RLE ++R EQ +E R R+
Sbjct: 333 LKRELEEIREREQRLEQEERREQLLAEEVREQARE 367
Score = 33.9 bits (76), Expect = 0.12
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLS 114
EE +L R+L E + +++ R E +L +E+ R ++ + EEI ER++ ++
Sbjct: 292 EERREQQLRRELEEIREREQRLEQEERREQRLEQEERREQQLKRELEEIREREQRLEQEE 351
Query: 115 NIQHALERLEKDRSEQRQE--CRRMRR 139
+ L ++++ +R E RR +R
Sbjct: 352 RREQLLAEEVREQARERGESLTRRWQR 378
Score = 32.7 bits (73), Expect = 0.26
Identities = 29/86 (33%), Positives = 45/86 (51%), Gaps = 5/86 (5%)
Query: 55 EEDLRPELERDLREFLAFVE-EVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRL 113
E++LR E +R RE + E QEL R + +E+E+L ++ + EE L R E +L
Sbjct: 1227 EQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQERE--EERLRRQERARKL 1284
Query: 114 SNIQHALERLEKDRSEQRQECRRMRR 139
+ L L +++ EQR R RR
Sbjct: 1285 REEEEQL--LFEEQEEQRLRQERDRR 1308
Score = 31.2 bits (69), Expect = 0.77
Identities = 23/86 (26%), Positives = 44/86 (50%), Gaps = 7/86 (8%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLS 114
E++LR E +R R EE Q L E + L+ +ER + + E++L ++ + RL
Sbjct: 1249 EQELRRERDRKFR------EEEQLLQEREEERLRRQERARKLREEEEQLLFEEQEEQRLR 1302
Query: 115 NIQHALERLEKDRSEQRQECRRMRRD 140
+ R E ++ + ++ RR+ R+
Sbjct: 1303 QERDRRYRAE-EQFAREEKSRRLERE 1327
Score = 30.0 bits (66), Expect = 1.7
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 13/84 (15%)
Query: 52 TLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKD 111
+L E LR E ++ + EE + R EL+ L+E+E+L+ + + A+++ E D ++
Sbjct: 447 SLRERQLRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRR-ERAQQLQEEDSFQE 505
Query: 112 RLSNIQHALERLEKDRSEQRQECR 135
+++R ++QE R
Sbjct: 506 ------------DRERRRRQQEQR 517
Score = 29.3 bits (64), Expect = 2.9
Identities = 38/121 (31%), Positives = 51/121 (41%), Gaps = 25/121 (20%)
Query: 22 EELRKKA--FEEDLFLNIRHPEGTTTIAELI-RTLLEEDLRPELERDLREFLAFVEEVQE 78
EE RKK FE+ R E EL R EE LR RD EF +EE Q
Sbjct: 150 EEQRKKRERFEQHYSRQYRDKEQRLQRQELEERRAEEEQLRRRKGRDAEEF---IEEEQ- 205
Query: 79 LSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRMR 138
L+ +E+ E K + EE +R E ++ QH E+ E+ ++ R R
Sbjct: 206 --------LRRREQQELKRELREEEQQRRERRE-----QH-----ERALQEEEEQLLRQR 247
Query: 139 R 139
R
Sbjct: 248 R 248
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/97 (30%), Positives = 46/97 (46%), Gaps = 15/97 (15%)
Query: 55 EEDLRP----------ELERDLREFLAFV-EEVQELSRLELKLLKEKERLEEKLKTAEEI 103
EE L E ER LRE + E QEL R + L+E+E+L ++ + EE
Sbjct: 915 EEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQERE--EER 972
Query: 104 LERDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
L R E +L + L R E++ ++R R+ R +
Sbjct: 973 LRRQERARKLREEEQLLRREEQELRQERD--RKFREE 1007
Score = 27.7 bits (60), Expect = 8.5
Identities = 20/71 (28%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 74 EEVQELSRLELKLLKEKERLEE----KLKTAEEILERDELKDRLSNIQHALERLEKDRSE 129
E+ +EL+ E + K++ER E+ + + E+ L+R EL++R + + R +D E
Sbjct: 141 EQERELAEEE-EQRKKRERFEQHYSRQYRDKEQRLQRQELEERRAEEEQLRRRKGRDAEE 199
Query: 130 QRQECRRMRRD 140
+E + RR+
Sbjct: 200 FIEEEQLRRRE 210
Score = 27.7 bits (60), Expect = 8.5
Identities = 30/116 (25%), Positives = 48/116 (40%), Gaps = 10/116 (8%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDL---RPELERDLREFLAFVEEVQ 77
L + R + F E+ L E E R EE+ R ELE R+ E
Sbjct: 996 LRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQFRQ------ERD 1049
Query: 78 ELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQE 133
RLE ++ +EKE + + + + +E + R + L R E+DR + +E
Sbjct: 1050 RKFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRR-ERDRKFREEE 1104
>RA50_PYRAB (Q9UZC8) DNA double-strand break repair rad50 ATPase
Length = 880
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/125 (26%), Positives = 65/125 (51%), Gaps = 19/125 (15%)
Query: 23 ELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSRL 82
E KA EE I+ E AE IR L E +E+ L E +VEE+++ ++
Sbjct: 324 ESELKAIEEV----IKEGEKKKERAEEIREKLSE-----IEKRLEELKPYVEELEDAKQV 374
Query: 83 ELKLLKEKERLE--------EKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQEC 134
+ ++ + K RL+ EKL++ E+ ER E+++ + I + ++E++++E+ +
Sbjct: 375 QKQIERLKARLKGLSPGEVIEKLESLEK--ERTEIEEAIKEITTRIGQMEQEKNERMKAI 432
Query: 135 RRMRR 139
+R+
Sbjct: 433 EELRK 437
Score = 32.3 bits (72), Expect = 0.35
Identities = 39/140 (27%), Positives = 66/140 (46%), Gaps = 28/140 (20%)
Query: 13 KMASYIVALEEL--RKKAFEEDLFLNIRH-PEGTTTIAELIRTLLEEDLRPELERDLREF 69
K++ + +E+L RKK EE + R E I+EL + + E E++ R+
Sbjct: 243 KISELKIQVEKLKGRKKGLEEKIVQIERSIEEKKAKISELEEIVKDIPKLQEKEKEYRKL 302
Query: 70 LAFVEEVQ-ELSRLELKLLK---EKERLEEKLKTAEEILER-DELKDRLSNI-------- 116
F +E + +L RLE +L K E + +EE +K E+ ER +E++++LS I
Sbjct: 303 KGFRDEYESKLRRLEKELSKWESELKAIEEVIKEGEKKKERAEEIREKLSEIEKRLEELK 362
Query: 117 ------------QHALERLE 124
Q +ERL+
Sbjct: 363 PYVEELEDAKQVQKQIERLK 382
Score = 30.4 bits (67), Expect = 1.3
Identities = 38/136 (27%), Positives = 61/136 (43%), Gaps = 12/136 (8%)
Query: 4 LEQFSVREKKMASYI--VALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLR-- 59
+E++++ KK+ + EE + + L + +R IAE I+ L E L+
Sbjct: 458 MERYTLEIKKIEEELKRTTEEERKLRVNLRKLEIKLREFSVMRDIAEQIKEL-ESKLKGF 516
Query: 60 --PELERDLREFLAFVEEVQELSRLELKL---LKEKERLEEKLKTAEEILERDELKDRLS 114
ELE+ REF EE +L L L LK + LE + K EE + + K+ L
Sbjct: 517 NLEELEQKEREFEGLNEEFNKLKGELLGLERDLKRIKALEGRRKLIEEKVRK--AKEELE 574
Query: 115 NIQHALERLEKDRSEQ 130
N+ L L + E+
Sbjct: 575 NLHRQLRELGFESVEE 590
Score = 29.6 bits (65), Expect = 2.2
Identities = 27/108 (25%), Positives = 48/108 (44%), Gaps = 10/108 (9%)
Query: 25 RKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLEL 84
R KA EE +R +G + R L EE + +ER E EE++ + E
Sbjct: 428 RMKAIEE-----LRKAKGKCPVCG--RELTEEHKKELMERYTLEIKKIEEELKRTTEEER 480
Query: 85 KLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQ 132
KL +LE KL+ E ++ +++ ++ L+ + EQ++
Sbjct: 481 KLRVNLRKLEIKLR---EFSVMRDIAEQIKELESKLKGFNLEELEQKE 525
Score = 28.1 bits (61), Expect = 6.5
Identities = 32/132 (24%), Positives = 65/132 (49%), Gaps = 11/132 (8%)
Query: 4 LEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPE-GTTTIAELIRTLLEEDLR-PE 61
LE+ R K + +EE +KA EE L+ + E G ++ EL +LR E
Sbjct: 545 LERDLKRIKALEGRRKLIEEKVRKAKEELENLHRQLRELGFESVEEL-------NLRIQE 597
Query: 62 LERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALE 121
LE +++ + EL L+ KL KEK L++ + ++ +E++++ + ++
Sbjct: 598 LEEFHDKYVEAKKSESELRELKNKLEKEKTELDQAFEMLADV--ENEIEEKEAKLKDLES 655
Query: 122 RLEKDRSEQRQE 133
+ ++ E+++E
Sbjct: 656 KFNEEEYEEKRE 667
Score = 27.7 bits (60), Expect = 8.5
Identities = 32/138 (23%), Positives = 63/138 (45%), Gaps = 17/138 (12%)
Query: 4 LEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLR-PEL 62
LE+F + + L EL+ K +E L+ + +A++ + E++ + +L
Sbjct: 598 LEEFHDKYVEAKKSESELRELKNKLEKEKTELD----QAFEMLADVENEIEEKEAKLKDL 653
Query: 63 ERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEIL-----------ERDELKD 111
E E + E+ + L +LE ++ RLEE K+ E+I ER++ K
Sbjct: 654 ESKFNEE-EYEEKRERLVKLEREVSSLTARLEELKKSVEQIKATLRKLKEEKEEREKAKL 712
Query: 112 RLSNIQHALERLEKDRSE 129
+ ++ AL ++E R +
Sbjct: 713 EIKKLEKALSKVEDLRKK 730
>RA50_METKA (Q8TXI4) DNA double-strand break repair rad50 ATPase
Length = 876
Score = 40.4 bits (93), Expect = 0.001
Identities = 40/133 (30%), Positives = 65/133 (48%), Gaps = 34/133 (25%)
Query: 38 RHPEGTTTIAELIRTLLEE---------DLRPELER--DLREFLAFVEEVQ-ELSRLE-- 83
R P G + E +R L EE + ELER +L E + E + EL R+E
Sbjct: 572 RTPSGVEDVEEELRRLEEERDHVGQKLREAEGELERYHNLEEKVKRAREARKELKRIERD 631
Query: 84 --------------LKLLKEK----ERLEEKLKTAEEILERDELKDRLSNIQHALERLEK 125
L+ L+E+ +RLEE+L++ E+ ER ++D+LS ++ L +EK
Sbjct: 632 LEDAKGRLEQVERNLEGLRERYGSEDRLEEELESVEKKYER--VRDKLSEVKGRLNGMEK 689
Query: 126 DRSEQRQECRRMR 138
R E +++ R+ R
Sbjct: 690 RREELKKQVRKYR 702
Score = 36.2 bits (82), Expect = 0.024
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 27/147 (18%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREF 69
+ ++ A ++ + E + + F E +R +G+ + + LEE L+R+++E
Sbjct: 168 KAREQAHELLRVAEAKLETFRE----RVRDLKGSKKELKRVERELEE-----LKREVKEL 218
Query: 70 LAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILE-----RDELK-------------D 111
VEE++E + +E ERLE +L+ E +E RD+L+
Sbjct: 219 EPEVEELKERLNELREAKREFERLEGELRLLENKIESLKGRRDDLRKLVEEGKEAERELQ 278
Query: 112 RLSNIQHALERLEKDRSEQRQECRRMR 138
RL ++ + LE + +E R+ +R
Sbjct: 279 RLGDVPSKVRELENEEAELRRRIEELR 305
Score = 34.7 bits (78), Expect = 0.070
Identities = 24/58 (41%), Positives = 34/58 (58%), Gaps = 9/58 (15%)
Query: 85 KLLKEKERLEEKLKTAEEIL--ERDELKDRLSNIQHALE-------RLEKDRSEQRQE 133
KLL++ E+ E+L+ EE L ER ELKDRL +++ LE RL + R E +E
Sbjct: 446 KLLRDAEKELERLQGREEDLRKERRELKDRLESVRRELEGTKERMWRLRERREELERE 503
Score = 33.5 bits (75), Expect = 0.15
Identities = 40/120 (33%), Positives = 59/120 (48%), Gaps = 17/120 (14%)
Query: 22 EELRKKAFE-EDLFLNIRHP-EGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQEL 79
E+LRK+ E +D ++R EGT +R + R ELER+L E EE+ +L
Sbjct: 463 EDLRKERRELKDRLESVRRELEGTKERMWRLR-----ERREELERELEEIEELKEELADL 517
Query: 80 SRLELKLLKEKERLEE--KLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRM 137
SR +L E++RL E L E L RD L+ R ++ RLEK+ C ++
Sbjct: 518 SR---ELGVEEDRLPELRDLAVRAESLLRD-LERRRGDVL----RLEKELERTLDRCEKV 569
Score = 31.6 bits (70), Expect = 0.59
Identities = 23/73 (31%), Positives = 41/73 (55%), Gaps = 9/73 (12%)
Query: 73 VEEVQE-LSRLELKLLKEKERLEEKLKTAEEILER----DELKDRLSNIQHALERLEKDR 127
VE+V+E L RLE +E++ + +KL+ AE LER +E R + L+R+E+D
Sbjct: 577 VEDVEEELRRLE----EERDHVGQKLREAEGELERYHNLEEKVKRAREARKELKRIERDL 632
Query: 128 SEQRQECRRMRRD 140
+ + ++ R+
Sbjct: 633 EDAKGRLEQVERN 645
Score = 30.4 bits (67), Expect = 1.3
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 26/143 (18%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLL-EEDLRPELER---------DLREFL 70
LEEL+ +A + L + + +E +R L EE+L+ +LE+ D E L
Sbjct: 332 LEELKDEAGVDPERL-VEFKDKIVEASERLRDLRREEELKRKLEKVSDELSELGDREETL 390
Query: 71 -AFVEEVQE-LSRLELKL----LKEKERLE--EKLKTAE-------EILERDELKDRLSN 115
+ EE+QE L ++ +L +KEKE LE E L+ AE L R+ + L +
Sbjct: 391 QSEYEELQERLDEIQGELKEIRVKEKELLERIESLREAEGECPVCLRKLPRERAEKLLRD 450
Query: 116 IQHALERLEKDRSEQRQECRRMR 138
+ LERL+ + R+E R ++
Sbjct: 451 AEKELERLQGREEDLRKERRELK 473
>TRHY_SHEEP (P22793) Trichohyalin
Length = 1549
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 23/99 (23%)
Query: 51 RTLLEEDLRPE---------LERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAE 101
R LEE+L+ E L R+ RE ++E+V EL R E +L +EK R E + + E
Sbjct: 744 RKYLEEELQQEEDRLQREKQLLREDREKRQYLEKV-ELQREEEQLQREKRRQERERQYRE 802
Query: 102 EILERDELKDRLSNIQHALERL-EKDRSEQRQECRRMRR 139
E L R+E ERL K++ QR+EC + RR
Sbjct: 803 EELLREE------------ERLHRKEQQLQREECEKRRR 829
Score = 37.0 bits (84), Expect = 0.014
Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 32/142 (22%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
+E +K EE+ L R EL R E LR E +R RE ++E ++L R
Sbjct: 1165 QERDRKFREEEQLLQERE--------ELRRQEREPQLRQERDRKFREEEQLLQEREKLRR 1216
Query: 82 LEL--KLLKEKERL----EEKLKTAEEILERDELKDR--------LSNIQHALERLEKDR 127
E +L +E++R E+ L+ EE L R E +DR L + L R E+DR
Sbjct: 1217 QEREPQLRQERDRKFHEEEQLLQEREEQLRRQE-RDRKFREEAQLLQEREEQLRRQERDR 1275
Query: 128 ---------SEQRQECRRMRRD 140
E+ ++ RR RD
Sbjct: 1276 KFREEEQLLQEREEQLRRQERD 1297
Score = 37.0 bits (84), Expect = 0.014
Identities = 31/93 (33%), Positives = 43/93 (45%), Gaps = 9/93 (9%)
Query: 56 EDLRPELERDLREFLAFVEEVQ------ELSRLELK---LLKEKERLEEKLKTAEEILER 106
E R E ER E + EE Q E R E + L KE +R EE+L+ E++L
Sbjct: 610 EKRRQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEKELQRQEERLQEEEQLLRE 669
Query: 107 DELKDRLSNIQHALERLEKDRSEQRQECRRMRR 139
+ K R + LE++E EQ Q R +R
Sbjct: 670 EREKRRQERERQYLEKVELQEEEQLQREEREKR 702
Score = 36.6 bits (83), Expect = 0.018
Identities = 26/89 (29%), Positives = 50/89 (55%), Gaps = 5/89 (5%)
Query: 55 EEDLRPE--LERDLREFLAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDEL 109
EE L+ E L R+ RE E Q L ++EL+ L+ +ER + + + + LE++EL
Sbjct: 657 EERLQEEEQLLREEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKEEL 716
Query: 110 KDRLSNIQHALERLEKDRSEQRQECRRMR 138
+ + +Q E+L+++ E+R++ R +
Sbjct: 717 QRQEERLQREKEQLQREDREKRRQVRERK 745
Score = 36.6 bits (83), Expect = 0.018
Identities = 16/68 (23%), Positives = 41/68 (59%), Gaps = 3/68 (4%)
Query: 75 EVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQ---HALERLEKDRSEQR 131
E++EL E + ++++R ++L+ ++ +R EL++R +Q + L+++R E+
Sbjct: 179 ELEELLNREQRFERQEQRERQRLQVEQQQRQRGELRERQEEVQLQKRETQELQRERLEEE 238
Query: 132 QECRRMRR 139
Q+ ++ +R
Sbjct: 239 QQLQKQKR 246
Score = 36.2 bits (82), Expect = 0.024
Identities = 29/92 (31%), Positives = 56/92 (60%), Gaps = 9/92 (9%)
Query: 53 LLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDE--LK 110
L +E+L+ + ER RE E++Q R + + ++E++ LEE+L+ E+ L+R++ L+
Sbjct: 711 LEKEELQRQEERLQRE----KEQLQREDREKRRQVRERKYLEEELQQEEDRLQREKQLLR 766
Query: 111 DRLSNIQHALERLEKDRSEQ--RQECRRMRRD 140
+ Q+ LE++E R E+ ++E RR R+
Sbjct: 767 EDREKRQY-LEKVELQREEEQLQREKRRQERE 797
Score = 35.8 bits (81), Expect = 0.031
Identities = 32/102 (31%), Positives = 50/102 (48%), Gaps = 13/102 (12%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERD 107
+L R E+ LR E +R RE L+ E ++ R E +LL+E+E E+L+ E +
Sbjct: 971 QLRRLEREQQLRQERDRKFREELSRQERDRKF-REEEQLLQERE---EQLRRQERDRKFR 1026
Query: 108 ELKDRLSNIQHALERLEKDR---------SEQRQECRRMRRD 140
E + L + L R E+DR E+ ++ RR RD
Sbjct: 1027 EEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERD 1068
Score = 35.4 bits (80), Expect = 0.041
Identities = 42/154 (27%), Positives = 65/154 (41%), Gaps = 28/154 (18%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLRE- 68
R++K L+E ++ ++ R E + E E+ LR E R RE
Sbjct: 1044 RDRKFREEEQLLQEREEQLRRQERDRKFREEEQQLRLLER-----EQQLRQERNRKFREE 1098
Query: 69 -FLAFVEEVQELSRLELKLLKEKERL----EEKLKTAEEILERDELKDR--------LSN 115
L EE L E +L ++++R E+ L+ EE L R E +DR L
Sbjct: 1099 QLLREREEQLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRRQE-RDRKFREEAQILKE 1157
Query: 116 IQHALERLEKDRS--------EQRQECRRMRRDP 141
+ L R E+DR ++R+E RR R+P
Sbjct: 1158 REEQLRRQERDRKFREEEQLLQEREELRRQEREP 1191
Score = 35.4 bits (80), Expect = 0.041
Identities = 33/103 (32%), Positives = 53/103 (51%), Gaps = 12/103 (11%)
Query: 47 AELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLEL--KLLKEKERL---EEKLKTAE 101
A++++ E+ R E +R RE ++E +EL R E +L +E++R EE+L
Sbjct: 1152 AQILKEREEQLRRQERDRKFREEEQLLQEREELRRQEREPQLRQERDRKFREEEQLLQER 1211
Query: 102 EILERDELKDRLSNIQ----HALERLEKDRSEQRQECRRMRRD 140
E L R E + +L + H E+L ++R EQ RR RD
Sbjct: 1212 EKLRRQEREPQLRQERDRKFHEEEQLLQEREEQ---LRRQERD 1251
Score = 35.0 bits (79), Expect = 0.053
Identities = 40/130 (30%), Positives = 58/130 (43%), Gaps = 14/130 (10%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELS 80
LEE RK EE + + E R EE R E +R RE ++E +E
Sbjct: 959 LEEDRKFREEEQQLRRLEREQQLRQ--ERDRKFREELSRQERDRKFREEEQLLQEREEQL 1016
Query: 81 RLELKLLKEKERLEEKLKTAEEILERDELKDR--------LSNIQHALERLEKDRS--EQ 130
R + + K +E E+ L+ EE L R E +DR L + L R E+DR E+
Sbjct: 1017 RRQERDRKFREE-EQLLQEREEQLRRQE-RDRKFREEEQLLQEREEQLRRQERDRKFREE 1074
Query: 131 RQECRRMRRD 140
Q+ R + R+
Sbjct: 1075 EQQLRLLERE 1084
Score = 34.7 bits (78), Expect = 0.070
Identities = 36/148 (24%), Positives = 62/148 (41%), Gaps = 25/148 (16%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREF 69
R++K L+E ++ ++ R E +L++ E+ R E +R RE
Sbjct: 1250 RDRKFREEAQLLQEREEQLRRQERDRKFREEE------QLLQEREEQLRRQERDRKFREE 1303
Query: 70 LAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKD--- 126
++E +E R + + K +E E+ LK +EE L R E + +H L E+
Sbjct: 1304 EQLLQEREEQLRRQERDRKFREE-EQLLKESEEQLRRQERDRKFHEKEHLLREREEQQLR 1362
Query: 127 ---------------RSEQRQECRRMRR 139
R+EQ +E RR R+
Sbjct: 1363 RQELEGVFSQEEQLRRAEQEEEQRRQRQ 1390
Score = 34.3 bits (77), Expect = 0.091
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 12/106 (11%)
Query: 46 IAELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLL------KEKERLEEKLKT 99
I+E +++L E+ R L+++ R + +++E S+ L +E+ R EE+L+
Sbjct: 339 ISEEVQSLQEDQGRQRLKQEQRYDQNWRWQLEEESQRRRYTLYAKPAQREQVREEEQLRL 398
Query: 100 AEEILERD------ELKDRLSNIQHALERLEKDRSEQRQECRRMRR 139
EE L+R+ E + R +Q ERL+++ + ++E R RR
Sbjct: 399 KEEKLQREKRRQERERQYREVELQREEERLQREEEQLQREEREKRR 444
Score = 34.3 bits (77), Expect = 0.091
Identities = 31/94 (32%), Positives = 44/94 (45%), Gaps = 12/94 (12%)
Query: 59 RPELERDLREFLAFVEEVQELSRL--ELKLLKEKER-LEEKLKTAEEILERDELKDRLSN 115
R E R L E F EE Q+L RL E +L +E++R E+L E + E + L
Sbjct: 952 REEKIRYLEEDRKFREEEQQLRRLEREQQLRQERDRKFREELSRQERDRKFREEEQLLQE 1011
Query: 116 IQHALERLEKDR---------SEQRQECRRMRRD 140
+ L R E+DR E+ ++ RR RD
Sbjct: 1012 REEQLRRQERDRKFREEEQLLQEREEQLRRQERD 1045
Score = 32.7 bits (73), Expect = 0.26
Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 13/120 (10%)
Query: 23 ELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELE-RDLREFLAFVEE-VQELS 80
ELR++ +E++ L R + EL R LEE+ + + + R L E L E QEL
Sbjct: 212 ELRER--QEEVQLQKRETQ------ELQRERLEEEQQLQKQKRGLEERLLEQERREQELR 263
Query: 81 RLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
R E + +++ R E++ T EEI ER E R S Q LE E D +++ R R++
Sbjct: 264 RKEQERREQQLRQEQEEATQEEISERGE--SRTSRCQWQLES-EADARQRKVYSRPHRQE 320
Score = 32.7 bits (73), Expect = 0.26
Identities = 22/61 (36%), Positives = 36/61 (58%), Gaps = 3/61 (4%)
Query: 73 VEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQ 132
V E ++L E KL +EK R E + + E L+R+E +RL + L+R E+++ +RQ
Sbjct: 390 VREEEQLRLKEEKLQREKRRQERERQYREVELQREE--ERLQREEEQLQREEREK-RRRQ 446
Query: 133 E 133
E
Sbjct: 447 E 447
Score = 32.0 bits (71), Expect = 0.45
Identities = 25/91 (27%), Positives = 43/91 (46%), Gaps = 9/91 (9%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERD 107
+L R EE+ R + +RD + F+EE Q L R + + + + K EE L R+
Sbjct: 1375 QLRRAEQEEEQRRQRQRDRK----FLEEEQSLQREREEEKRRVQEQDRKFLEQEEQLHRE 1430
Query: 108 ELKD-----RLSNIQHALERLEKDRSEQRQE 133
E ++ +L A E+ ++ +RQE
Sbjct: 1431 EQEELRRRQQLDQQYRAEEQFAREEKRRRQE 1461
Score = 31.2 bits (69), Expect = 0.77
Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 4/121 (3%)
Query: 21 LEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELS 80
L + R + F E+L R + +L++ E+ R E +R RE ++E +E
Sbjct: 981 LRQERDRKFREELSRQERDRKFREE-EQLLQEREEQLRRQERDRKFREEEQLLQEREEQL 1039
Query: 81 RLELKLLKEKERLEEKL-KTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRMRR 139
R + + K +E EE+L + EE L R E + + L LE+++ +++ R+ R
Sbjct: 1040 RRQERDRKFRE--EEQLLQEREEQLRRQERDRKFREEEQQLRLLEREQQLRQERNRKFRE 1097
Query: 140 D 140
+
Sbjct: 1098 E 1098
Score = 30.8 bits (68), Expect = 1.0
Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREF 69
RE++ + EE R + EE L R + +E +L+R+ RE
Sbjct: 412 RERQYREVELQREEERLQREEEQLQREEREKRRRQEREKQYLEKVELWEEEQLQREEREK 471
Query: 70 LAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKD 126
E Q L ++EL+ L+ +ER + + + + LE+ EL++ + L+R E++
Sbjct: 472 RRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQE-----EEQLQREERE 526
Query: 127 RSEQRQE 133
+ Q +E
Sbjct: 527 KRRQERE 533
Score = 30.4 bits (67), Expect = 1.3
Identities = 38/138 (27%), Positives = 64/138 (45%), Gaps = 18/138 (13%)
Query: 4 LEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELE 63
L+ VRE + + L++ +++ E + R + AE LLE + + E E
Sbjct: 879 LDDSWVRESQFQQDLRPLQDEQEEKREREQEWRSRQKRDSQFPAE---QLLEREQQKETE 935
Query: 64 RDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALE-R 122
R R+F R E +LLK + EEK++ EE + E + +L ++ + R
Sbjct: 936 RRDRKF-----------REEEQLLKGQR--EEKIRYLEEDRKFREEEQQLRRLEREQQLR 982
Query: 123 LEKDRSEQRQECRRMRRD 140
E+DR + R+E R RD
Sbjct: 983 QERDR-KFREELSRQERD 999
Score = 30.4 bits (67), Expect = 1.3
Identities = 21/76 (27%), Positives = 42/76 (54%), Gaps = 8/76 (10%)
Query: 61 ELERDLREFLAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDELKDRLSNIQ 117
+L+R RE E Q L ++EL+ L+ +ER + + + ++ LE+ EL++ +
Sbjct: 547 QLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVELQE-----E 601
Query: 118 HALERLEKDRSEQRQE 133
L+R E+++ Q +E
Sbjct: 602 EQLQRQEREKRRQERE 617
Score = 30.0 bits (66), Expect = 1.7
Identities = 38/142 (26%), Positives = 66/142 (45%), Gaps = 13/142 (9%)
Query: 5 EQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELER 64
EQ +E++ + L K +E+ ++ E E R LE++L+ + ER
Sbjct: 602 EQLQRQEREKRRQERERQYLEKVELQEEE--QVQRQEREKRRQERERQYLEKELQRQEER 659
Query: 65 DLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDEL-KDRLSNIQHALERL 123
L+E + E +E R E +E++ LE+ EE L+R+E K R + LE+
Sbjct: 660 -LQEEEQLLREEREKRRQE----RERQYLEKVELQEEEQLQREEREKRRQERERQYLEKE 714
Query: 124 EKDRSEQR-----QECRRMRRD 140
E R E+R ++ +R R+
Sbjct: 715 ELQRQEERLQREKEQLQREDRE 736
Score = 30.0 bits (66), Expect = 1.7
Identities = 24/74 (32%), Positives = 37/74 (49%), Gaps = 10/74 (13%)
Query: 75 EVQELSRLELKLLKEKERLEEKLKTAEEILER---------DELKDRLSNIQHALERLEK 125
E + L R EL+ L E+E L EK E+ L+R +EL+ R + E L +
Sbjct: 128 EERRLKRQELEELAEEEELREKQVRREQRLQRREQEEYGGEEELQQRPKG-RELEELLNR 186
Query: 126 DRSEQRQECRRMRR 139
++ +RQE R +R
Sbjct: 187 EQRFERQEQRERQR 200
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 55 EEDLRPELERDLR----EFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
EE LR + ERD + E L E Q+L R EL+ + +E E+L+ AE+ E+ +
Sbjct: 1334 EEQLRRQ-ERDRKFHEKEHLLREREEQQLRRQELEGVFSQE---EQLRRAEQEEEQRRQR 1389
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMRR 139
R + L+++R E+++ + R
Sbjct: 1390 QRDRKFLEEEQSLQREREEEKRRVQEQDR 1418
Score = 29.6 bits (65), Expect = 2.2
Identities = 21/76 (27%), Positives = 42/76 (54%), Gaps = 8/76 (10%)
Query: 61 ELERDLREFLAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDELKDRLSNIQ 117
+L+R+ RE E Q L ++EL+ L+ +ER + + + ++ LE+ EL++ +
Sbjct: 519 QLQREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQE-----E 573
Query: 118 HALERLEKDRSEQRQE 133
L+R E+ + Q +E
Sbjct: 574 EQLQRQERQKRRQERE 589
Score = 29.3 bits (64), Expect = 2.9
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 8/76 (10%)
Query: 61 ELERDLREFLAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDELKDRLSNIQ 117
+L+R RE E Q L ++EL+ L+ +ER + + + + LE+ EL++ +
Sbjct: 491 QLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKVELQE-----E 545
Query: 118 HALERLEKDRSEQRQE 133
L+R E+++ Q +E
Sbjct: 546 EQLQRQEREKRRQERE 561
Score = 28.1 bits (61), Expect = 6.5
Identities = 19/83 (22%), Positives = 45/83 (53%), Gaps = 8/83 (9%)
Query: 61 ELERDLREFLAFVEEVQELSRLELK---LLKEKERLEEKLKTAEEILERDELKDRLSNIQ 117
+L+R R+ E Q L ++EL+ L+ +ER + + + + LE+ EL++ +
Sbjct: 575 QLQRQERQKRRQEREKQYLEKVELQEEEQLQRQEREKRRQERERQYLEKVELQE-----E 629
Query: 118 HALERLEKDRSEQRQECRRMRRD 140
++R E+++ Q +E + + ++
Sbjct: 630 EQVQRQEREKRRQERERQYLEKE 652
>NIN_MOUSE (Q61043) Ninein
Length = 2035
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/96 (31%), Positives = 49/96 (50%), Gaps = 18/96 (18%)
Query: 54 LEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEE----------- 102
L+E+LR E ER+L+ A +++ E R E + L + EEK++ E+
Sbjct: 715 LQEELRQEHERELQ---ARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEE 771
Query: 103 --ILERDELKDRLSNIQHALERLEKDRSEQRQECRR 136
LE++EL++ LS +H L++ R E EC R
Sbjct: 772 KHALEKEELREELS--EHHRRELQEGREEMETECNR 805
Score = 33.1 bits (74), Expect = 0.20
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 23/100 (23%)
Query: 59 RPELERDLREFLAFVEEVQELSRLELKLLKEKERLE-EKLKTAEEILERDELKDRLS-NI 116
R ELE+++++ A EE RL L L KE RLE E L+ AE++ E + L +L ++
Sbjct: 452 RVELEQEIQK--AKTEENYIRDRLALSL-KENNRLETELLENAEKLAEYESLTQKLQRSL 508
Query: 117 QHAL------------------ERLEKDRSEQRQECRRMR 138
++ L ERL + R+E Q+CR ++
Sbjct: 509 ENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQ 548
Score = 30.0 bits (66), Expect = 1.7
Identities = 27/91 (29%), Positives = 44/91 (47%), Gaps = 9/91 (9%)
Query: 53 LLEEDLRPEL-ERDLREFLAFVEEVQ-----ELSRLELKLLKEKERLEEKLKTAEEILE- 105
L +E+LR EL E RE EE++ +S++E + + E++ E + + LE
Sbjct: 775 LEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEV 834
Query: 106 --RDELKDRLSNIQHALERLEKDRSEQRQEC 134
R EL+D L + E ++ E QEC
Sbjct: 835 RHRQELRDLLDQHLEERSQWEFEKDELTQEC 865
Score = 30.0 bits (66), Expect = 1.7
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 12/69 (17%)
Query: 58 LRPELER--------DLREFLAFVEEVQELSRLELKLLKEKERLEEKLKT-AEEILERDE 108
L+ ELER DL +F +++ + KLLKEKE L E+LK+ A+++ E
Sbjct: 1668 LKDELERLKQLHRCPDLSDFQ---QKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSL 1724
Query: 109 LKDRLSNIQ 117
L+ R++ ++
Sbjct: 1725 LEHRIATMK 1733
>MYSP_CAEEL (P10567) Paramyosin
Length = 882
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/148 (23%), Positives = 66/148 (43%), Gaps = 14/148 (9%)
Query: 1 ASHLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE----- 55
A + EQ + +K++ A L+ + E L +++ + T + E R LE
Sbjct: 341 AEYEEQIEIMLQKISQLEKAKSRLQSEV--EVLIVDLEKAQNTIALLERAREQLERQVGE 398
Query: 56 -----EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
+++ ELE RE A E+Q++ L K +++KE L + K + E E K
Sbjct: 399 LKVRIDEITVELEAAQRELRAVNAELQKMKHLYEKAVEQKEALARENKKLHD--ELHEAK 456
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMR 138
+ L++ L L+ + + E R ++
Sbjct: 457 EALADANRKLHELDLENARLAGEIRELQ 484
Score = 28.1 bits (61), Expect = 6.5
Identities = 34/142 (23%), Positives = 63/142 (43%), Gaps = 22/142 (15%)
Query: 4 LEQFSVREKKMASYIVALEELR---------KKAFEEDLFLNIRHPEGTTTIAELIRTLL 54
L+Q+++ ++K+A+ LEE + +K E DL E I++LI
Sbjct: 612 LDQYALAQRKVAALSAELEECKTALDNAIRARKQAEVDL------EEANGRISDLISINN 665
Query: 55 E-EDLRPELERDLREFLAFVEEVQELSRLELKLLKEK--ERLEEKLKTAEEILERDELKD 111
++ +LE +L A ++EV + EL E+ L + + E++ E E
Sbjct: 666 NLTSIKNKLETELSTAQADLDEVTK----ELHAADERANRALADAARAVEQLHEEQEHSM 721
Query: 112 RLSNIQHALERLEKDRSEQRQE 133
++ ++ +LE K Q QE
Sbjct: 722 KIDALRKSLEEQVKQLQVQIQE 743
>MYS2_DICDI (P08799) Myosin II heavy chain, non muscle
Length = 2116
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/127 (26%), Positives = 66/127 (51%), Gaps = 10/127 (7%)
Query: 11 EKKMASYIVALEELRKKAFEEDLFLN--IRHPEGTTTIAELIRTLLEE--DLRPELERDL 66
EKK+ S + ++E++++ +E L + ++ E +R LEE D R ELE
Sbjct: 1670 EKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSK 1729
Query: 67 REFLAFVEEVQELSRLEL----KLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALER 122
R VE++++ E+ KL + K++L + + T ++ LE + K +L+ + A +R
Sbjct: 1730 RRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDE--KKKLNESERAKKR 1787
Query: 123 LEKDRSE 129
LE + +
Sbjct: 1788 LESENED 1794
Score = 30.0 bits (66), Expect = 1.7
Identities = 18/67 (26%), Positives = 34/67 (49%), Gaps = 2/67 (2%)
Query: 74 EEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQE 133
EE+QE +L L K K++ EE+L+ + + D D +S ++ + L+K+ E +
Sbjct: 933 EELQEEQKLRNTLEKLKKKYEEELEEMKRV--NDGQSDTISRLEKIKDELQKEVEELTES 990
Query: 134 CRRMRRD 140
+D
Sbjct: 991 FSEESKD 997
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/144 (20%), Positives = 71/144 (48%), Gaps = 24/144 (16%)
Query: 19 VALEELRKKAFEEDLFL-NIRHPEGTTTIAELIRTLLEE-----DLRPELERDLREFLAF 72
+ +E++ + E+ L L N+++ + ++ E +R L EE LR LE+ +++
Sbjct: 898 IRVEDMESELDEKKLALENLQNQK--RSVEEKVRDLEEELQEEQKLRNTLEKLKKKYEEE 955
Query: 73 VEEVQELSRLELKLLKEKERLEEKL-KTAEEILE---------------RDELKDRLSNI 116
+EE++ ++ + + E+++++L K EE+ E R L+ L ++
Sbjct: 956 LEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTRVRLQSELDDL 1015
Query: 117 QHALERLEKDRSEQRQECRRMRRD 140
L+ KD+SE ++ +++ +
Sbjct: 1016 TVRLDSETKDKSELLRQKKKLEEE 1039
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC
2.7.1.37)
Length = 1142
Score = 40.0 bits (92), Expect = 0.002
Identities = 27/105 (25%), Positives = 52/105 (48%), Gaps = 5/105 (4%)
Query: 33 LFLNIRHPEGTTTIAELIRTLLEED----LRPELERDLREFLAFVEEVQELSRLELKLLK 88
L +++ TT + L E+D + E +R F ++E+ E + E ++ K
Sbjct: 503 LIPSMKRESVTTKLMSTYAKLAEDDDWEYIEKETKRTSSNFATLIDEIFEYEKYE-QIRK 561
Query: 89 EKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQE 133
EKE LE K++ A+ E + + + + A + LEK+ +++QE
Sbjct: 562 EKEELERKVREAKAREELERRRRKQEEKERARKLLEKEDLKRKQE 606
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 39.7 bits (91), Expect = 0.002
Identities = 29/98 (29%), Positives = 49/98 (49%), Gaps = 8/98 (8%)
Query: 41 EGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTA 100
E I+EL +T R ELE +L + E++ K LKE + EE LK
Sbjct: 1072 ENVNKISELTKT------REELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEE 1125
Query: 101 EEILERD--ELKDRLSNIQHALERLEKDRSEQRQECRR 136
+ LE++ E K +L++++ LE LEK+ + + ++
Sbjct: 1126 KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKK 1163
Score = 34.7 bits (78), Expect = 0.070
Identities = 29/97 (29%), Positives = 52/97 (52%), Gaps = 11/97 (11%)
Query: 54 LEEDLRPELERDLREFLAFVEE----VQE-LSRLELKLLKEKERLE---EKLKTAEEILE 105
+E D + +LE L+E L +E V+E L +LE + KEK LE E +K E +E
Sbjct: 1457 IERDNKRDLE-SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIE 1515
Query: 106 RDE--LKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
+E LK + I+ + E+LE+ + ++ + ++ +
Sbjct: 1516 SNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHE 1552
Score = 33.1 bits (74), Expect = 0.20
Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 7/137 (5%)
Query: 2 SHLEQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPE 61
+ LE+ KK+ S I + E K + E + + + + E I+ L E + +
Sbjct: 1498 AELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHE--KSD 1555
Query: 62 LERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEIL-----ERDELKDRLSNI 116
L + E +EE++ R+E K E E ++++L A+E + E LK +L +I
Sbjct: 1556 LISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDI 1615
Query: 117 QHALERLEKDRSEQRQE 133
+ L+ + + ++E
Sbjct: 1616 ERELKDKQAEIKSNQEE 1632
Score = 32.7 bits (73), Expect = 0.26
Identities = 21/73 (28%), Positives = 41/73 (55%), Gaps = 9/73 (12%)
Query: 73 VEEVQELSRLELKLLKE-------KERLEEKLKTAEEILERDELKDRLSNIQHALERLEK 125
V ++ EL++ +L E K LE KL+T+E+ L+ E+K+ +++ +LEK
Sbjct: 1074 VNKISELTKTREELEAELAAYKNLKNELETKLETSEKALK--EVKENEEHLKEEKIQLEK 1131
Query: 126 DRSEQRQECRRMR 138
+ +E +Q+ +R
Sbjct: 1132 EATETKQQLNSLR 1144
Score = 28.9 bits (63), Expect = 3.8
Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 30/140 (21%)
Query: 23 ELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLE-----EDLRPELERDLREFLAFVEEVQ 77
E KK+ EED+ N++H + ++LI + E E+L+ +L + + Q
Sbjct: 1536 EQSKKSAEEDI-KNLQHEK-----SDLISRINESEKDIEELKSKLRIEAKSGSELETVKQ 1589
Query: 78 ELSRLELKL---------LKEK-ERLEEKLKTAEEIL-----ERDELKDRLSNIQHALE- 121
EL+ + K+ LK K E +E +LK + + E++ L RL ++ L+
Sbjct: 1590 ELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDS 1649
Query: 122 ---RLEKDRSEQRQECRRMR 138
+ +K E+R E R+ +
Sbjct: 1650 TQQKAQKSEEERRAEVRKFQ 1669
>CAFA_MOUSE (Q9QWF0) Chromatin assembly factor 1 subunit A (CAF-1
subunit A) (Chromatin assembly factor I p150 subunit)
(CAF-I 150 kDa subunit) (CAF-Ip150)
Length = 911
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/92 (35%), Positives = 51/92 (54%), Gaps = 8/92 (8%)
Query: 56 EDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELK-DRLS 114
E R E E+ LRE + +E + E K LKEKER E++ K +E E+ LK ++
Sbjct: 323 EQQREEKEK-LREEIRRAKEEARKKKEEEKELKEKERREKREKDEKEKAEKQRLKEEKRK 381
Query: 115 NIQHALE-RLEKDRSEQ-----RQECRRMRRD 140
Q ALE +LE+ R ++ R+E +R+R +
Sbjct: 382 ERQEALEAKLEEKRKKEEEKRLREEEKRLREE 413
>YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome III
precursor
Length = 887
Score = 39.3 bits (90), Expect = 0.003
Identities = 29/90 (32%), Positives = 55/90 (60%), Gaps = 6/90 (6%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAF-VEEVQELSRLELKLLKEKERLEEKLKTAEEILER 106
EL R LEE R E ER +E +A + +++EL RL+L+ ++ ER+ ++L+ A + +
Sbjct: 373 ELERIRLEEKKR-ENERVRQEEIAMEISKIRELERLQLERQRKNERVRQELEAARKYKLQ 431
Query: 107 DELKDRLSNIQHALERLEKDRSEQRQECRR 136
+E +R IQ +++E ++ Q++E R+
Sbjct: 432 EE--ERQRKIQQ--QKVEMEQIRQQEEARQ 457
Score = 33.9 bits (76), Expect = 0.12
Identities = 36/134 (26%), Positives = 62/134 (45%), Gaps = 13/134 (9%)
Query: 5 EQFSVREKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTL-LEEDLRPELE 63
E VR++++A I + EL + E R E E R L+E+ E +
Sbjct: 385 ENERVRQEEIAMEISKIRELERLQLERQ-----RKNERVRQELEAARKYKLQEE---ERQ 436
Query: 64 RDLREFLAFVEEV--QELSRLELKLLKEKERLEEKLKTAEEILERDELKD--RLSNIQHA 119
R +++ +E++ QE +R E + E+ER E + +E LER + R
Sbjct: 437 RKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQK 496
Query: 120 LERLEKDRSEQRQE 133
++LEKDR ++ Q+
Sbjct: 497 KKKLEKDREQREQQ 510
Score = 27.7 bits (60), Expect = 8.5
Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 12/81 (14%)
Query: 53 LLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDR 112
+LEE+ ELER +R+ EE++ ++E+ +E+++ ++KL+ E E+ E ++
Sbjct: 462 VLEEERARELER-VRQ-----EELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEEL 515
Query: 113 LSNIQHALERLEKDRSEQRQE 133
I +EK+ E +Q+
Sbjct: 516 NRMI------IEKEMKENKQK 530
>TRHY_HUMAN (Q07283) Trichohyalin
Length = 1898
Score = 39.3 bits (90), Expect = 0.003
Identities = 29/95 (30%), Positives = 52/95 (54%), Gaps = 6/95 (6%)
Query: 46 IAELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILE 105
+ EL R EE + ER R F EE +E + E L KE+E+L+E+ + L+
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 106 RDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
+E ++L ++ + L ++R E+ Q+ +R+RR+
Sbjct: 273 EEE--EQLRKLER--QELRRERQEEEQQQQRLRRE 303
Score = 37.4 bits (85), Expect = 0.011
Identities = 28/84 (33%), Positives = 43/84 (50%), Gaps = 4/84 (4%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLS 114
+E L+ E + R E QE R E +++ER E++LK E E + L+ RL
Sbjct: 636 DERLKREEPEEERRHELLKSEEQEERRHEQLRREQQERREQRLKREE---EEERLEQRLK 692
Query: 115 NIQHALERLEKDRSEQRQECRRMR 138
+H ER E++ +E+ QE R R
Sbjct: 693 R-EHEEERREQELAEEEQEQARER 715
Score = 36.6 bits (83), Expect = 0.018
Identities = 32/130 (24%), Positives = 59/130 (44%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREF 69
+E++ + LEE ++ +E +R + L R EE L+ L + +
Sbjct: 499 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 558
Query: 70 LAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSE 129
E +++L + E + E+ER E++LK +E LK Q L+R +++R E
Sbjct: 559 REQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 618
Query: 130 QRQECRRMRR 139
QR + + R
Sbjct: 619 QRLKREEVER 628
Score = 35.4 bits (80), Expect = 0.041
Identities = 29/101 (28%), Positives = 52/101 (50%), Gaps = 10/101 (9%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEK---LKTAEEIL 104
+L+R E+ R E ER R+ +E ++L R E +EK RL+E+ + EE+
Sbjct: 1019 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE----REKRRLQERERQYREEEELQ 1074
Query: 105 ERDEL---KDRLSNIQHALERLEKDRSEQRQECRRMRRDPP 142
+ +E ++R + + LER + E +QE ++ R+ P
Sbjct: 1075 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1115
Score = 35.0 bits (79), Expect = 0.053
Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 8/87 (9%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAE-EILERDELKDRL 113
EE + L+R+ E L Q L R E++ L+++ER +E+LK E E R EL
Sbjct: 602 EERRQQRLKREQEERLE-----QRLKREEVERLEQEERRDERLKREEPEEERRHELLKSE 656
Query: 114 SNIQHALERLEKDRSEQRQECRRMRRD 140
+ E+L +++ E+R++ R++R+
Sbjct: 657 EQEERRHEQLRREQQERREQ--RLKRE 681
Score = 34.3 bits (77), Expect = 0.091
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 9/88 (10%)
Query: 59 RPELERDLREFLAFVEEVQELSRLELKLLKEKERL-----EEKLKTAEEILERDELKDRL 113
R ELER R+ +E ++L R E + + +ER EE+L+ EE L R+E + R
Sbjct: 1090 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1149
Query: 114 SNIQHALERLEKDRSE-QRQECRRMRRD 140
+ LER ++ E QRQ+ ++ RD
Sbjct: 1150 ---RQELERQYREEEELQRQKRKQRYRD 1174
Score = 34.3 bits (77), Expect = 0.091
Identities = 40/149 (26%), Positives = 65/149 (42%), Gaps = 18/149 (12%)
Query: 10 REKKMASYIVALEELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEED---LRPELERDL 66
RE+K L + R + F E+ L E E R LEE+ R E +R
Sbjct: 1400 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1459
Query: 67 RE--------FLAFVEEVQELSR--LELKLLKEKERLEEKLKTAEEILERD-----ELKD 111
RE F+EE Q+L R + K L+E+++L + + + +RD E +
Sbjct: 1460 REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL 1519
Query: 112 RLSNIQHALERLEKDRSEQRQECRRMRRD 140
R + L R E+DR + +E + R++
Sbjct: 1520 RQEREEQQLSRQERDRKFRLEEQKVRRQE 1548
Score = 32.7 bits (73), Expect = 0.26
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 10/81 (12%)
Query: 55 EEDLRPELERDLREFLAFVEEV----QELSRLELKLLKEKERLEEKLKTAEEILERDELK 110
E+ L+ E E + R++L EE QE + +LK +E+ER E LK EE ER E +
Sbjct: 463 EQRLKREQE-ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE--ERREQQ 519
Query: 111 DRLSNIQHALERLEKDRSEQR 131
+R + L R +++R EQR
Sbjct: 520 ERR---EQQLRREQEERREQR 537
Score = 32.3 bits (72), Expect = 0.35
Identities = 21/86 (24%), Positives = 50/86 (57%), Gaps = 2/86 (2%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEILERDELKDRLS 114
+E+ R E + + RE E+ +E +L+ +++ER E++L+ +E R++ R
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRR-EQEERREQQLRREQEEERREQQLRREQ 368
Query: 115 NIQHALERLEKDRSEQRQECRRMRRD 140
+ ++L +++ E+R+E +++RR+
Sbjct: 369 EEERREQQLRREQEEERRE-QQLRRE 393
Score = 32.0 bits (71), Expect = 0.45
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 11/93 (11%)
Query: 55 EEDLRPELERDLREFLAFVEEVQ---ELSRLELKLLKEKE-RLEEKLKTAEEILERDELK 110
++ L+ + E + RE +EE + + R E +L +E+E R E++LK EE + L+
Sbjct: 492 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE---EERLQ 548
Query: 111 DRLSNIQHALERLEKDRSEQ---RQECRRMRRD 140
RL + Q L R +++R EQ R+E +R+ ++
Sbjct: 549 QRLRSEQQ-LRREQEERLEQLLKREEEKRLEQE 580
Score = 31.2 bits (69), Expect = 0.77
Identities = 29/95 (30%), Positives = 45/95 (46%), Gaps = 23/95 (24%)
Query: 50 IRTLLEEDLRPELERDLRE--FLAFVEEVQELSRL------ELKLLKEKERLEEKLKTAE 101
+R E LR E ER RE FL EE ++ R EL+ L+E+E+L+
Sbjct: 808 LREQRERQLRAE-ERQQREQRFLPEEEEKEQRGRQRREREKELQFLEEEEQLQR------ 860
Query: 102 EILERDELKDRLSNIQHALERLEKDRSEQRQECRR 136
++R +Q + L++D+ +RQE RR
Sbjct: 861 --------RERAQQLQEEEDGLQEDQERRRQEQRR 887
Score = 30.8 bits (68), Expect = 1.0
Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKE-----RLEEKLKTAEE 102
+L+R E+ E ER RE +E ++L E + + +E R EE+L+ EE
Sbjct: 1049 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1108
Query: 103 ILERDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
L R+E + R + R E++ ++ ++ R R+
Sbjct: 1109 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1146
Score = 30.0 bits (66), Expect = 1.7
Identities = 36/118 (30%), Positives = 56/118 (46%), Gaps = 27/118 (22%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQ----------ELSRLELKLLKEKERLEE-- 95
+L+R E+ R ELER RE EE+Q E R +LK E E+
Sbjct: 1139 QLLREEREKRRRQELERQYRE----EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1194
Query: 96 ------KLKTAEEI--LERDELKDRLS--NIQHAL-ERLEKDRSEQRQECRRMRRDPP 142
K + E+ LE +++DR S ++QH L E+ E+DR ++R+ ++ R P
Sbjct: 1195 DNKVYCKGRENEQFRQLEDSQVRDRQSQQDLQHLLGEQQERDREQERRRWQQANRHFP 1252
Score = 29.6 bits (65), Expect = 2.2
Identities = 25/87 (28%), Positives = 41/87 (46%), Gaps = 1/87 (1%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLL-KEKERLEEKLKTAEEILERDELKDRL 113
EE LR ++LR E+ Q+ R E +L K++E E+ + E ER E ++
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 114 SNIQHALERLEKDRSEQRQECRRMRRD 140
Q E+ E+ + R+E RR+
Sbjct: 335 REQQLRREQEERREQQLRREQEEERRE 361
Score = 29.6 bits (65), Expect = 2.2
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 74 EEVQELSRLELKLLKEKERLEEKLKTAE---EILERDELKDRLSNIQHALERLEKDRSEQ 130
E++QE + L+E+E KL+ E E E ++ + RL Q + E++R EQ
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 131 RQECRRMR 138
++E R +
Sbjct: 318 QEERREQQ 325
Score = 29.3 bits (64), Expect = 2.9
Identities = 27/98 (27%), Positives = 49/98 (49%), Gaps = 8/98 (8%)
Query: 48 ELIRTLLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERL-----EEKLKTAEE 102
+L+R E+ R E ER R+ ++ ++L E + + +ER EE+L+ EE
Sbjct: 959 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1018
Query: 103 ILERDELKDRLSNIQHALERLEKDRSEQRQECRRMRRD 140
L R+E + R + ER + + E +QE ++ R+
Sbjct: 1019 QLLREEREKRR---RQEWERQYRKKDELQQEEEQLLRE 1053
Score = 29.3 bits (64), Expect = 2.9
Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 24/103 (23%)
Query: 55 EEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLKTAEEI----------- 103
E+ LR E E + E + E R E +L +E+E + LK EE
Sbjct: 441 EQQLRREQEEERHE------QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 494
Query: 104 LERD---ELKDRLSNIQHALERLEKDRSEQR----QECRRMRR 139
L+RD E ++R ++ R +++R EQ+ QE RR +R
Sbjct: 495 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 537
Score = 29.3 bits (64), Expect = 2.9
Identities = 28/89 (31%), Positives = 49/89 (54%), Gaps = 6/89 (6%)
Query: 53 LLEEDLRPELERDLREFLAFVEEVQELSRLELKLLKEKERL--EEKLKTAEEILERDELK 110
LL+E+ EL+R+ RE E+ ++ R E +L +E+E+L EE+ K + ER K
Sbjct: 922 LLQEE-EEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLREEREKRRRQERERQYRK 979
Query: 111 DRLSNIQHALERLEKDRSEQRQECRRMRR 139
D+ +Q E+L + E+R+ R ++
Sbjct: 980 DK--KLQQKEEQLLGEEPEKRRRQEREKK 1006
Score = 28.5 bits (62), Expect = 5.0
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 8/118 (6%)
Query: 22 EELRKKAFEEDLFLNIRHPEGTTTIAELIRTLLEEDLRPELERDLREFLAFVEEVQELSR 81
+EL+++ EE L +R + E R EE+ EL+++ + L E +
Sbjct: 1041 DELQQE--EEQL---LREEREKRRLQERERQYREEE---ELQQEEEQLLGEERETRRRQE 1092
Query: 82 LELKLLKEKERLEEKLKTAEEILERDELKDRLSNIQHALERLEKDRSEQRQECRRMRR 139
LE + KE+E +E+ + E E+ ++R + E +++ R+E + RR
Sbjct: 1093 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1150
Score = 28.1 bits (61), Expect = 6.5
Identities = 31/101 (30%), Positives = 48/101 (46%), Gaps = 16/101 (15%)
Query: 48 ELIRTLLEEDLRP-ELERDLREFLAFVEEVQELSRLELKLLKEKERLEEKLK--TAEEIL 104
E R L + +R + ++DL+ L E QE R + E+ R ++ + EE L
Sbjct: 1206 EQFRQLEDSQVRDRQSQQDLQHLLG---EQQERDREQ-----ERRRWQQANRHFPEEEQL 1257
Query: 105 ERDELK-----DRLSNIQHALERLEKDRSEQRQECRRMRRD 140
ER+E K DR S + L R E++ +RQE R R+
Sbjct: 1258 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1298
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.316 0.135 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,779,402
Number of Sequences: 164201
Number of extensions: 686438
Number of successful extensions: 7987
Number of sequences better than 10.0: 880
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 5936
Number of HSP's gapped (non-prelim): 2313
length of query: 142
length of database: 59,974,054
effective HSP length: 99
effective length of query: 43
effective length of database: 43,718,155
effective search space: 1879880665
effective search space used: 1879880665
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Lotus: description of TM0142.1