BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0122.3
(1172 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BMS1_SCHPO (O94653) Ribosome biogenesis protein BMS1 homolog 826 0.0
BMS1_YEAST (Q08965) Ribosome biogenesis protein BMS1 774 0.0
BMS1_HUMAN (Q14692) Ribosome biogenesis protein BMS1 homolog 510 e-144
MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein) 57 3e-07
DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contai... 57 4e-07
INCE_MOUSE (Q9WU62) Inner centromere protein 55 9e-07
SR40_YEAST (P32583) Suppressor protein SRP40 53 6e-06
ITN1_MOUSE (Q9Z0R4) Intersectin 1 (EH and SH3 domains protein 1) 51 2e-05
DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin... 50 3e-05
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 50 3e-05
ITN1_RAT (Q9WVE9) Intersectin 1 (EH domain and SH3 domain regula... 50 4e-05
ITN1_HUMAN (Q15811) Intersectin 1 (SH3 domain-containing protein... 50 4e-05
ATRX_RAT (P70486) Transcriptional regulator ATRX (X-linked nucle... 50 4e-05
ITN1_XENLA (O42287) Intersectin 1 49 1e-04
TRHY_RABIT (P37709) Trichohyalin 48 2e-04
TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protei... 48 2e-04
GAR2_SCHPO (P41891) Protein gar2 47 2e-04
DMP1_MOUSE (O55188) Dentin matrix acidic phosphoprotein 1 precur... 47 2e-04
A3B1_HUMAN (O00203) Adapter-related protein complex 3 beta 1 sub... 47 3e-04
TRHY_HUMAN (Q07283) Trichohyalin 47 4e-04
>BMS1_SCHPO (O94653) Ribosome biogenesis protein BMS1 homolog
Length = 1121
Score = 826 bits (2134), Expect = 0.0
Identities = 498/1202 (41%), Positives = 699/1202 (57%), Gaps = 152/1202 (12%)
Query: 11 KAHRIRQSGAKSFKKKQNKKKKQDDDDGLIDKPQNPRAFAFSSTNKAKRLKSRAVEKEQR 70
K H + SG K+ KKK K DG NP+AFA +S + R R + Q+
Sbjct: 5 KGHYAKHSGPKAEKKKLKKVS-----DG--SASNNPKAFAVASAGRMARQAMRTADISQK 57
Query: 71 RLHVPITDRSYGE-PAPYVIVVQGPPQVGKSLLIKSLVKHYTKHNLPEVRGPITIVSGKQ 129
+LHVP+ DR+ E P P ++ V GPP GKS LIKSLV+ Y+K+ + ++ GPIT+V+GK+
Sbjct: 58 KLHVPMVDRTPDEAPPPVIVAVMGPPGTGKSTLIKSLVRRYSKYTISQITGPITVVAGKK 117
Query: 130 RRLQFVECPNDINGMIDAAKFADLALLLIDGSYGFEMETFEFLNILQVHGFPKVMGVLTH 189
RR+ F+ECPND++ MID AK ADL LLLID ++GFEMET EFLNIL HG P++MGVLTH
Sbjct: 118 RRITFLECPNDLSSMIDVAKIADLVLLLIDANFGFEMETMEFLNILAPHGMPRIMGVLTH 177
Query: 190 LDKFKDVKKLRKTKQRLKHRFWTEIYDGAKLFYLSGLIHGKYVKREVHNLARFISVMKFH 249
LD FK LR+ K+RLKHRFWTE+Y GAKLFYLSG+++G+Y RE+ NL+RFISVMKF
Sbjct: 178 LDLFKKTSTLREAKKRLKHRFWTELYQGAKLFYLSGVLNGRYPDREILNLSRFISVMKFR 237
Query: 250 PLSWRTSHPYVLADRFEDITPPEKVHSNNKCDRKITLYGYLRGCNLKKGN-KVHIAGVGD 308
PL WR HPY+LADR ED+T P + N K RKITLYGYL G NL K + VHI GVGD
Sbjct: 238 PLRWRNQHPYLLADRMEDLTLPVDIEQNPKVGRKITLYGYLHGTNLPKHDASVHIPGVGD 297
Query: 309 YSLAGVTALPDPCPLPSAAK--KKGLRDKEKLFYAPMSGLGDLLYDKDAVYININDHFVQ 366
+ + V++L DPCP P A K ++ L +K+KL Y PM+ +G +L+DKD VYI +
Sbjct: 298 FVTSDVSSLEDPCPPPDADKVRRRRLSEKQKLIYGPMADIGGILFDKDRVYIEVPTS--N 355
Query: 367 FTKVDDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGA 426
F+K DENS E GE +V LQE + P+ NS + LF+ S
Sbjct: 356 FSK--DENS-------EAGFGERMVMQLQEAQQPLGVD-GNSGLQLFSNSD--------- 396
Query: 427 NMDVEQDGIIETVNYNEMDSDGGSESSDQDEADAMT---GSGLPDQ---AEDDAAGDKST 480
I+TV+ ESS+ D T +GL +Q ED+ A D S
Sbjct: 397 --------AIDTVD---------RESSEIDNVGRKTRRQPTGLINQELIKEDEGAFDDSD 439
Query: 481 NKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSG------NEDGSASDDGASSDSESL 534
N AD+++ +D +G NED S +++ A +DS+S
Sbjct: 440 ----------------------VNSADENEDVDFTGKIGAINNEDESDNEEVAFADSDSD 477
Query: 535 NEEEEDDVMGNVSKWKESLAERTL------SQKTPSLMQLVYGES-TVNLISINKENDSS 587
+ DD N+ +WKE LA + ++ ++ ++ Y ES + + +S+
Sbjct: 478 LGGQFDDEDSNL-RWKEGLASKAALAYSQSGKRRRNIQKIFYDESLSPKDAYAEYKGESA 536
Query: 588 EDEESD-------GDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKD-NE 639
+ ESD DFF+ + +V +++ ++ + +E + + K+W+
Sbjct: 537 KSSESDLVVSDDEEDFFK-VSKVANESISSN-HEKLMESE-----SDRLSKKWENPQLLA 589
Query: 640 EIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETGEKIENNQTDDAT------ 693
++++RF+TG+L + + E DD GDFEDLE E +N+ ++++
Sbjct: 590 QLKSRFITGSLLDSI------EGQEEVSQDDEEGDFEDLEDEENSSDNEMEESSGSSVTA 643
Query: 694 ---HNGDDLEAETRRLKKLALQEDGGNENEAKFR-----RGQP--NETSYFDKLKEEIEL 743
+ D+++ +T R +E+ + E + R RG P + ++ + KE+I
Sbjct: 644 ENEESADEVDFQTER------EENARKKEELRLRFEEEDRGDPEKKDVDWYTEEKEKIAR 697
Query: 744 QKQMNIAELNDLDEATRLEIEGFRTGTYVRLEVHDVPCEMVEYFDPYHPILIGGVGLGEE 803
Q +N D+D +R EIEG+R GTYVR+ ++DVP E VE+FD +P+++GG+ E+
Sbjct: 698 QLVINREAFEDMDPESRAEIEGYRAGTYVRIVINDVPFEFVEHFDSRYPVVVGGLLPNEQ 757
Query: 804 NVGYMQARLKRHRWHKKVLKTRDPIIVSAGWRRYQTTPVYAIEDHNGRHRMLKYTPEHMH 863
G +Q R+KRHRWHKK+LKT DP+I S GWRR+Q+ PVY+I D R+RMLKYTPEHMH
Sbjct: 758 RYGLVQVRIKRHRWHKKILKTNDPLIFSMGWRRFQSIPVYSISDSRTRNRMLKYTPEHMH 817
Query: 864 CLAMFYGPLAPPNTGIVAVQNLSNNQA---TFRITATAVVLEFNHAARIVKKIKLVGYPC 920
C FYGP PN+G AVQ+++N+ A +FRI AT VL + + IVKK+KL G P
Sbjct: 818 CFGTFYGPFVAPNSGFCAVQSVANSFAKAGSFRIAATGSVLNIDQSTDIVKKLKLTGVPY 877
Query: 921 KIFKKTALIKEMFTSDLEIARFEGAAIRTVSGIRGQVKKAAKEEIGNQPKRKGGITKEGI 980
KIFK TA IK+MF+S LE+A+FEGA IRTVSGIRGQVKKA +E G+
Sbjct: 878 KIFKNTAFIKKMFSSPLEVAKFEGANIRTVSGIRGQVKKAVDQEHGH------------- 924
Query: 981 ARCTFEDKILMSDIVFLRAWTQVEVPQFYNPLTTALQPRDQTWKGMRTVAELRRDHDLPV 1040
R TFEDKILMSDIVFLRAW V+V +F +T L+ W GMR E+R + L
Sbjct: 925 FRATFEDKILMSDIVFLRAWYPVQVRKFCTMVTNLLETDKTEWNGMRLTGEVRHELGLKT 984
Query: 1041 PVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEP 1100
P+ +S Y++I R R FNPL VP SLQ +LPF S+ K R++P Q+R V++
Sbjct: 985 PLRPNSQYQEIVRPSRHFNPLKVPASLQAQLPFNSRQKALRPRSKPTYMQKRT--VLLNA 1042
Query: 1101 RERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQ 1160
ERKV L+Q + ++ DK KRK K+ + + + KEEQ +++REE+ E +
Sbjct: 1043 EERKVRDLLQKVMTLHTDKEAKRKAKKAAEHERYHKRMQKEEQAYIEKKREEKAEWFAQH 1102
Query: 1161 DK 1162
K
Sbjct: 1103 GK 1104
>BMS1_YEAST (Q08965) Ribosome biogenesis protein BMS1
Length = 1183
Score = 774 bits (1999), Expect = 0.0
Identities = 483/1256 (38%), Positives = 694/1256 (54%), Gaps = 167/1256 (13%)
Query: 7 DQSNKAHRIRQSGAKSFKKKQNKKKKQDDDDGLIDKPQNPRAFAFSSTNKAKRLKSRAVE 66
+QSNK HR K+K KKK L + N +AFA ++ K R R+ +
Sbjct: 2 EQSNKQHR-------KAKEKNTAKKK------LHTQGHNAKAFAVAAPGKMARTMQRSSD 48
Query: 67 KEQRRLHVPITDRS-YGEPAPYVIVVQGPPQVGKSLLIKSLVKHYTKHNLPEVRGPITIV 125
+R+LHVP+ DR+ +P P+++ V GPP GK+ LI+SLV+ TK L +++GPIT+V
Sbjct: 49 VNERKLHVPMVDRTPEDDPPPFIVAVVGPPGTGKTTLIRSLVRRMTKSTLNDIQGPITVV 108
Query: 126 SGKQRRLQFVECP-NDINGMIDAAKFADLALLLIDGSYGFEMETFEFLNILQVHGFPKVM 184
SGK RRL F+ECP +D+N MID AK ADL LLLIDG++GFEMET EFLNI Q HG P+V+
Sbjct: 109 SGKHRRLTFLECPADDLNAMIDIAKIADLVLLLIDGNFGFEMETMEFLNIAQHHGMPRVL 168
Query: 185 GVLTHLDKFKDVKKLRKTKQRLKHRFWTEIYDGAKLFYLSGLIHGKYVKREVHNLARFIS 244
GV THLD FK LR +K+RLKHRFWTE+Y GAKLFYLSG+I+G+Y RE+ NL+RFIS
Sbjct: 169 GVATHLDLFKSQSTLRASKKRLKHRFWTEVYQGAKLFYLSGVINGRYPDREILNLSRFIS 228
Query: 245 VMKFHPLSWRTSHPYVLADRFEDITPPEKVHSNN-KCDRKITLYGYLRGCNLKK--GNKV 301
VMKF PL WR HPY+LADRF D+T PE + + + DRK+ +YGYL G L G +V
Sbjct: 229 VMKFRPLKWRNEHPYMLADRFTDLTHPELIETQGLQIDRKVAIYGYLHGTPLPSAPGTRV 288
Query: 302 HIAGVGDYSLAGVTALPDPCPLP----------------------------SAAKKKGLR 333
HIAGVGD+S+A + LPDPCP P + ++K L
Sbjct: 289 HIAGVGDFSVAQIEKLPDPCPTPFYQQKLDDFEREKMKEEAKANGEITTASTTRRRKRLD 348
Query: 334 DKEKLFYAPMSGLGDLLYDKDAVYININDHFVQFTKVDDENSDITRKGNERDIGEVLVRS 393
DK+KL YAPMS +G +L DKDAVYI+I K ++E S + G ER GE L+
Sbjct: 349 DKDKLIYAPMSDVGGVLMDKDAVYIDIG-------KKNEEPSFV--PGQERGEGEKLMTG 399
Query: 394 LQETKYPINEKLENSMINLFAQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESS 453
LQ + I EK + + LF+ +E + E ++ MD + G ES
Sbjct: 400 LQSVEQSIAEKFDGVGLQLFSNGTE----------------LHEVADHEGMDVESGEESI 443
Query: 454 DQDEADAMTGSGL-PDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSD-- 510
+ DE + + L + ++ + D+L E + ND D D
Sbjct: 444 EDDEGKSKGRTSLRKPRIYGKPVQEEDADIDNLPSDEE----------PYTNDDDVQDSE 493
Query: 511 --LMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLA---ERTLSQK-TPS 564
+++ N G + + +++S EE ED+ W+ + A ++T S+K T +
Sbjct: 494 PRMVEIDFNNTGEQGAEKLALETDSEFEESEDEF-----SWERTAANKLKKTESKKRTWN 548
Query: 565 LMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEE--VKKKN---VRDGLNDGNVNT 619
+ +L+Y ++ I + +D + + D E +++ +KK+ ++G D V+
Sbjct: 549 IGKLIYMDNISPEECIRRWRGEDDDSKDESDIEEDVDDDFFRKKDGTVTKEGNKDHAVDL 608
Query: 620 E---DYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFE 676
E Y + + K+W K + I+ RF+ + + K+ + E +++YGDFE
Sbjct: 609 EKFVPYFDTFEKLAKKW--KSVDAIKERFLGAGILG---NDNKTKSDSNEGGEELYGDFE 663
Query: 677 DLETG---EKIENN-------QTDDATHNGDD------------------LEAETRRLKK 708
DLE G E+ E+N + ++ NGDD E E KK
Sbjct: 664 DLEDGNPSEQAEDNSDKESEDEDENEDTNGDDDNSFTNFDAEEKKDLTMEQEREMNAAKK 723
Query: 709 LALQEDGGNENEAKFRRGQPNE--TSYFDKLKEEIELQKQMNIAELNDLDEATRLEIEGF 766
L+ E F+ N ++++ K +I Q ++N E ++ R IEGF
Sbjct: 724 EKLRAQFEIEEGENFKEDDENNEYDTWYELQKAKISKQLEINNIEYQEMTPEQRQRIEGF 783
Query: 767 RTGTYVRLEVHDVPCEMVEYFDPYHPILIGGVGLGEENVGYMQARLKRHRWHKKVLKTRD 826
+ G+YVR+ VP E V+ F+P PI++GG+ E G ++ARL+RHRWHKK+LKT D
Sbjct: 784 KAGSYVRIVFEKVPMEFVKNFNPKFPIVMGGLLPTEIKFGIVKARLRRHRWHKKILKTND 843
Query: 827 PIIVSAGWRRYQTTPVYAIEDHNGRHRMLKYTPEHMHCLAMFYGPLAPPNTGIVAVQNLS 886
P+++S GWRR+QT P+Y D R RMLKYTPEH +C A FYGPL PNT VQ ++
Sbjct: 844 PLVLSLGWRRFQTLPIYTTTDSRTRTRMLKYTPEHTYCNAAFYGPLCSPNTPFCGVQIVA 903
Query: 887 NNQA--TFRITATAVVLEFNHAARIVKKIKLVGYPCKIFKKTALIKEMFTSDLEIARFEG 944
N+ FRI AT +V E + IVKK+KLVG+P KIFK TA IK+MF+S +E+ARFEG
Sbjct: 904 NSDTGNGFRIAATGIVEEIDVNIEIVKKLKLVGFPYKIFKNTAFIKDMFSSAMEVARFEG 963
Query: 945 AAIRTVSGIRGQVKKAAKEEIGNQPKRKGGITKEGIARCTFEDKILMSDIVFLRAWTQVE 1004
A I+TVSGIRG++K+A + EG R FEDKILMSDIV LR+W V
Sbjct: 964 AQIKTVSGIRGEIKRALSK-------------PEGHYRAAFEDKILMSDIVILRSWYPVR 1010
Query: 1005 VPQFYNPLTTALQPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVP 1064
V +FYNP+T+ L WKG+R ++R +L P N DS Y KIER R FN L VP
Sbjct: 1011 VKKFYNPVTSLLLKEKTEWKGLRLTGQIRAAMNLETPSNPDSAYHKIERVERHFNGLKVP 1070
Query: 1065 RSLQERLPFASKPKE-TPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKR 1123
+++Q+ LPF S+ + P++ + + +R VV+ E+K + +Q + I+ K KR
Sbjct: 1071 KAVQKELPFKSQIHQMKPQKKKTYMAKR---AVVLGGDEKKARSFIQKVLTISKAKDSKR 1127
Query: 1124 KLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSS----------KKMRR 1169
K ++ +RK + AK E+ +R +E+++E + K + +KMRR
Sbjct: 1128 KEQKASQRKERLKKLAKMEEEKSQRDKEKKKEYFAQNGKRTTMGGDDESRPRKMRR 1183
>BMS1_HUMAN (Q14692) Ribosome biogenesis protein BMS1 homolog
Length = 1282
Score = 510 bits (1314), Expect = e-144
Identities = 321/873 (36%), Positives = 474/873 (53%), Gaps = 116/873 (13%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDV 430
DDE D + + + G S +E + N ++ + + + L + + MD+
Sbjct: 443 DDEEDDEMSEDDGLENGS----SDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDL 498
Query: 431 ----EQDGIIETVNYNEMDSDGGSESSDQDEADAMTG--SGLPDQAEDDAAGDKSTN--- 481
+ D +E + E +++ ESS++++ A SG E AG N
Sbjct: 499 PAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQS 558
Query: 482 -KDHLEEHI--------EFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGA----- 527
+ +LE+ + F +G +F ++ + + S E+ S +++
Sbjct: 559 DRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLS 618
Query: 528 -------------------SSDSESLNEEEEDDVMGN--------VSKWKESLAERTLS- 559
+SD E+L +EEED N KWKE L+ +
Sbjct: 619 KPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEA 678
Query: 560 -----QKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFF--EPIEEVKKKNVRDGL 612
Q P+L +L+YG T + N+E D EE G F +P E K K
Sbjct: 679 FLRQQQAAPNLRKLIYGTVTED----NEEEDDDTLEELGGLFRVNQPDRECKHK------ 728
Query: 613 NDGNVNTEDYSKCAQFMDKR---WDKKD-NEEIRNRFVTGNLAKAALRNGLPKATTEEEN 668
D C++F+ + WD ++ IR+ FVTG + A E+
Sbjct: 729 -------ADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKW-----EDDKDAAKVLAED 776
Query: 669 DDVYGDFEDLETGEKIE-----NNQTDD----ATHNGDDLEAETRRLKKLALQEDGGNEN 719
+++YGDFEDLETG+ + N Q +D D E E+ + K L +
Sbjct: 777 EELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMF 836
Query: 720 EAKFRRGQPNETSYFDKLKEEIELQKQMNIAELNDLDEATRLEIEGFRTGTYVRLEVHDV 779
+A++ G E++YFD LK E++ Q Q+N AE D D+ R++ EGFR G YVR+E+ +V
Sbjct: 837 DAEYDEG---ESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENV 893
Query: 780 PCEMVEYFDPYHPILIGGVGLGEENVGYMQARLKRHRWHKKVLKTRDPIIVSAGWRRYQT 839
PCE V+ FDP++PI++GG+G E NVGY+Q RLK+HRW+KK+LK+RDPII S GWRR+QT
Sbjct: 894 PCEFVQNFDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQT 953
Query: 840 TPVYAIEDHNGRHRMLKYTPEHMHCLAMFYGPLAPPNTGIVAVQNLSNNQATFRITATAV 899
P+Y IEDHNGR R+LKYTP+HMHC A F+GP+ P TG +A+Q++S FRI AT V
Sbjct: 954 IPLYYIEDHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGV 1013
Query: 900 VLEFNHAARIVKKIKLVGYPCKIFKKTALIKEMFTSDLEIARFEGAAIRTVSGIRGQVKK 959
VL+ + + +IVKK+KL G+P KIFK T+ IK MF S LE+A+FEGA IRTVSGIRGQ+KK
Sbjct: 1014 VLDLDKSIKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKK 1073
Query: 960 AAKEEIGNQPKRKGGITKEGIARCTFEDKILMSDIVFLRAWTQVEVPQFYNPLTTALQP- 1018
A + EG R +FEDK+LMSDIVF+R W V +P FYNP+T+ L+P
Sbjct: 1074 ALR-------------APEGAFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPV 1120
Query: 1019 -RDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKP 1077
TW GMRT +LR H + + NKDSLYK I R+ + FN L +P++LQ+ LPF +KP
Sbjct: 1121 GEKDTWSGMRTTGQLRLAHGVRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKP 1180
Query: 1078 KETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAE 1137
K K + + + RR+ V+ EP ERK+LAL+ + ++ KMKK K + + K H
Sbjct: 1181 KTQAKAGK-VPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRA 1239
Query: 1138 KAKEEQLSKKRRREERREKYRTQDKSSKKMRRS 1170
K KEE+ KR+++ R++ +R Q + ++ ++S
Sbjct: 1240 KQKEEEEKLKRQKDLRKKLFRIQGQKERRNQKS 1272
Score = 473 bits (1218), Expect = e-132
Identities = 285/755 (37%), Positives = 418/755 (54%), Gaps = 87/755 (11%)
Query: 8 QSNKAHRIRQSGAKSFKKKQNKKKKQDDDDGLIDKPQNPRAFAFSSTNKAKRLKSRAVEK 67
+ K HR + SG K+ KKK+ + D + +NP+AFA S + R R +
Sbjct: 4 KDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRTQDL 63
Query: 68 EQRRLHVPITDRSYGEPAPYVIVVQGPPQVGKSLLIKSLVKHYTKHNLPEVRGPITIVSG 127
+ ++ H+P+ DR+ EP P V+VV GPP+VGKS LI+ L++++T+ L E+RGP+TIVSG
Sbjct: 64 KTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTIVSG 123
Query: 128 KQRRLQFVECPNDINGMIDAAKFADLALLLIDGSYGFEMETFEFLNILQVHGFPKVMGVL 187
K+RRL +EC DIN MID AK ADL L+LID S+GFEMETFEFLNI QVHGFPK+MGVL
Sbjct: 124 KKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGVL 183
Query: 188 THLDKFKDVKKLRKTKQRLKHRFWTEIYDGAKLFYLSGLIHGKYVKREVHNLARFISVMK 247
THLD FK K+L+KTK+RLKHRFWTE+Y GAKLFYLSG++HG+Y +E+HNL RFI+VMK
Sbjct: 184 THLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMK 243
Query: 248 FHPLSWRTSHPYVLADRFEDITPPEKVHSNNKCDRKITLYGYLRGCNLKKGNKVHIAGVG 307
F PL+W+TSHPY+LADR ED+T PE + +N KCDRK++LYGYLRG +LK +++H+ GVG
Sbjct: 244 FRPLTWQTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMPGVG 303
Query: 308 DYSLAGVTALPDPCPLPSAAKKKGLRDKEKLFYAPMSGLGDLLYDKDAVYININDHFVQF 367
D++++ ++ LPDPC LP KK+ L +KEKL YAP+SG+G +LYDKDAVY+++ V
Sbjct: 304 DFAVSDISFLPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSHVFQ 363
Query: 368 TKVDDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGAN 427
+V + LV+SL T I+ K+ +S + LF+ S +E
Sbjct: 364 DEVGPTHE--------------LVQSLISTHSTIDAKMASSRVTLFSDSKPLGSE----- 404
Query: 428 MDVEQDGIIETVNYNEMDSDGG-------------SESSDQDEADAMTGSGLPDQAEDDA 474
D++ G++ +MD + G S SD +E D M+ + D
Sbjct: 405 -DIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDE 463
Query: 475 AGDKSTNKDHLEEHIEFHNGRRRRRAI-FGNDADQSDLMDSSGNEDGSASDDGASSDSES 533
++ N + ++++ +RR+ + ++ D DS + + S++++G + +++
Sbjct: 464 EAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADE 523
Query: 534 LNEEE-----EDDVMGNVSKWKESLA--------------ERTLSQKTPSLMQLVYGEST 574
+EEE E + G+ + + S A E++L K +L G T
Sbjct: 524 SSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCT 583
Query: 575 VNLI----SINKENDSSEDEESDGDFFEPIEE--VKKKNVRDGLNDGNVNTEDYSKCAQF 628
+ ++E+ S EE D + E I + K V G G N D + +
Sbjct: 584 AEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIEN 643
Query: 629 MDKRWDKKDNEEIRNRFVTGNL----------AKAALRN------------GLPKATTEE 666
+ K + E ++ +G L A+A LR G EE
Sbjct: 644 LLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEE 703
Query: 667 ENDDVYGDFEDLETGEKIENNQTD-DATHNGDDLE 700
E+DD E G NQ D + H D L+
Sbjct: 704 EDDDTLE-----ELGGLFRVNQPDRECKHKADSLD 733
>MDN1_YEAST (Q12019) Midasin (MIDAS-containing protein)
Length = 4910
Score = 57.0 bits (136), Expect = 3e-07
Identities = 78/312 (25%), Positives = 133/312 (42%), Gaps = 27/312 (8%)
Query: 422 EAQGANMDVEQDGIIETVNYNEM--DSDGGSESSDQDE----ADAMTGSGLPDQAEDDAA 475
E M+ + G +E ++ E D D SE + DE + + + D+ DD A
Sbjct: 4105 EDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKA 4164
Query: 476 GDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLN 535
D S KD +++++ N +A ND Q D + G+ED +A +DG N
Sbjct: 4165 SDNSKEKD-TDQNLDGKNQEEDVQAA-ENDEQQRDNKE-GGDEDPNAPEDGDEEIENDEN 4221
Query: 536 EEEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGD 595
EEE+DV + K+ E L P + L E +NL S ++E+D D SDG
Sbjct: 4222 AEEENDVGEQEDEVKDEEGE-DLEANVPEIETLDLPED-MNLDSEHEESDEDVD-MSDG- 4277
Query: 596 FFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAAL 655
+++ K+ V G D V E + D+ ++D E A+ +
Sbjct: 4278 ---MPDDLNKEEV--GNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDV 4332
Query: 656 RNGLPKATTEEEN---DDVYGDFEDLETGEKIENNQTDDATHNGDDLE-----AETRRL- 706
+ +EEN + D E+L+ +E N+ N + L+ A+T +
Sbjct: 4333 DMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDID 4392
Query: 707 KKLALQEDGGNE 718
++ A+Q+D G++
Sbjct: 4393 QEAAVQQDSGSK 4404
Score = 53.1 bits (126), Expect = 4e-06
Identities = 60/276 (21%), Positives = 118/276 (42%), Gaps = 44/276 (15%)
Query: 509 SDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMG---NVSKWKESLAERTLSQKTPSL 565
S+ +D ++G+ DG + + + + E+++D+ N +K ++ ER + ++
Sbjct: 4050 SEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENEDDAV 4109
Query: 566 MQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKC 625
+ +S +END DE++D + E EE+ D LN+ + N D
Sbjct: 4110 EMEGDMAGELEDLSNGEEND---DEDTDSEEEELDEEI------DDLNEDDPNAID---- 4156
Query: 626 AQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEEN-DDVYGDFEDLET---- 680
DK WD K ++ + + NL + A +E+ D+ G ED
Sbjct: 4157 ----DKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDG 4212
Query: 681 GEKIENNQTDDATHN------------GDDLEAETRRLKKLALQEDGG-------NENEA 721
E+IEN++ + ++ G+DLEA ++ L L ED ++ +
Sbjct: 4213 DEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDV 4272
Query: 722 KFRRGQPNETSYFDKLKEEIELQKQMNIAELNDLDE 757
G P++ + + E+ E++++ I N+ DE
Sbjct: 4273 DMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDE 4308
Score = 40.4 bits (93), Expect = 0.028
Identities = 84/406 (20%), Positives = 145/406 (35%), Gaps = 60/406 (14%)
Query: 372 DENSDITRKGNERDIGE-----------VLVRSLQETKYPINEKLENSMINLFAQSSEAL 420
+EN D E ++ E + + + K N K +++ NL ++ E
Sbjct: 4126 EENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQE-- 4183
Query: 421 AEAQGANMDVEQ----DGIIETVNYNEMDSDGGSESSDQDEADAMTGSG-LPDQAEDDAA 475
+ Q A D +Q +G E N E DG E + + A+ G D+ +D+
Sbjct: 4184 EDVQAAENDEQQRDNKEGGDEDPNAPE---DGDEEIENDENAEEENDVGEQEDEVKDEEG 4240
Query: 476 GDKSTNKDHLE-----EHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSD 530
D N +E E + + D D SD M N++ ++D
Sbjct: 4241 EDLEANVPEIETLDLPEDMNLDSEHEES----DEDVDMSDGMPDDLNKEEVGNEDEEVKQ 4296
Query: 531 SESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDE 590
+ + E+D G E+ + + + E + + +E S++E
Sbjct: 4297 ESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEE 4356
Query: 591 ESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNL 650
E D +EE K+K G NTE +D +K D E+I
Sbjct: 4357 ELKQD--AAMEENKEKG-------GEQNTEG-------LDGVEEKADTEDIDQEAAVQQ- 4399
Query: 651 AKAALRNGLPKATTEEENDDVYGD-------FEDLETGEKIENNQTDDAT----HNGDDL 699
+ + AT +E DDV G ED E K ++AT GD +
Sbjct: 4400 -DSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSM 4458
Query: 700 EAETRRLKKLALQEDGGNENEAKFRRGQ-PNETSYFDKLKEEIELQ 744
+ RR + + + G E+E + + P+E + + E + Q
Sbjct: 4459 KEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQ 4504
>DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contains:
Dentin phosphoprotein (Dentin phosphophoryn) (DPP);
Dentin sialoprotein (DSP)]
Length = 1253
Score = 56.6 bits (135), Expect = 4e-07
Identities = 60/328 (18%), Positives = 122/328 (36%), Gaps = 10/328 (3%)
Query: 373 ENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDVEQ 432
++SD + D + ++ N +S + + SS++ + +N
Sbjct: 697 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSS 756
Query: 433 DGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFH 492
D + + + DS S+SSD + S + D + S+N + +
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 493 NGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKES 552
+ + N +D SD +SS + D S S D SSDS+S N + N S +S
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD--SSDSDSSNRSDS----SNSSDSSDS 870
Query: 553 LAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGL 612
S + S ES+ + S + N S D + + + + +
Sbjct: 871 SDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 930
Query: 613 NDG-NVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEEND-- 669
N N N+ D S + D D ++ + N + N + ++ N + + +D
Sbjct: 931 NSSDNSNSSDSSNSSDSSDSS-DSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSS 989
Query: 670 DVYGDFEDLETGEKIENNQTDDATHNGD 697
D + ++ + ++ + D++ + D
Sbjct: 990 DSSDSSDSSDSSDSSNSSDSSDSSDSSD 1017
Score = 52.8 bits (125), Expect = 6e-06
Identities = 55/327 (16%), Positives = 123/327 (36%), Gaps = 17/327 (5%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDV 430
D ++SD + + D + S ++ + K ++S + S++ +++ +N
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 431 EQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIE 490
D + + N +S S+SSD ++ + + D ++ S+N + +
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSS---------SSDSSSSSDSSNSSDSSDSSD 700
Query: 491 FHNGRRRRRAIFGNDADQSDLMDSSG-----NEDGSASDDGASSDSESLNEEEEDDVMGN 545
N + +D+D SD DSS ++ ++SD SSDS + + +
Sbjct: 701 SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSD 760
Query: 546 VSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKK 605
S +S S + S +S+ + S + N S SD +
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820
Query: 606 KNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTE 665
N D N + + S + D D++ NR + N + ++ + ++
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDS-SNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 666 EENDDVYGDFEDLETGEKIENNQTDDA 692
++ D E + + +++ + D+
Sbjct: 880 SDSSDSSDSNESSNSSDSSDSSNSSDS 906
Score = 51.2 bits (121), Expect = 2e-05
Identities = 50/260 (19%), Positives = 100/260 (38%), Gaps = 13/260 (5%)
Query: 440 NYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRR 499
+YN +S SD A+ D D+ G+ + D ++ + +G+ +
Sbjct: 492 SYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND---DNDKSDSGKGKSD 548
Query: 500 AIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLS 559
+ + +D S+ DSS + D +SD +SSDS+S + + D + S S S
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 560 QKTPSLMQLVYGESTVNLISINKENDSSE-DEESDGDFFEPIEEVKKKNVRDGLNDGNVN 618
+ S +S + S E+DSS+ D +SD + + D N N +
Sbjct: 609 DSSDSSDSSDSSDSKSD--SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 619 TEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDL 678
S + D + + N + + + ++ ++E + D +
Sbjct: 667 DSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSS-------NSSESSDSSDSSDSDSS 719
Query: 679 ETGEKIENNQTDDATHNGDD 698
++ + +N +D + N D
Sbjct: 720 DSSDSSNSNSSDSDSSNSSD 739
Score = 48.9 bits (115), Expect = 8e-05
Identities = 55/337 (16%), Positives = 127/337 (37%), Gaps = 45/337 (13%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANM-- 428
+ ++SD + N D + S + + ++S + + SS++ ++ ++
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 712
Query: 429 --DVEQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLE 486
D + ++ N N DSD + S D +D+ S D ++ + + S + D
Sbjct: 713 SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS-- 770
Query: 487 EHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGA--SSDSESLNEEEEDDVMG 544
+ +D SD +SS + D S S D + S+ S+S N + D
Sbjct: 771 ----------------SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 545 NVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVK 604
+ + ++ + S + + N + +DSS+ +SD
Sbjct: 815 SSDSDSSNSSDSSNSSDS---------SDSSNSSDSSDSSDSSDSSDSD----------- 854
Query: 605 KKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATT 664
N D N + + S + D D+ E N + + + ++ + + +
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 914
Query: 665 EEENDDVYGDFEDLETGEKIENNQTDDATHNGDDLEA 701
+ +D + E+ +N+ + D++++ D ++
Sbjct: 915 SDSSDS-SNSSDSSESSNSSDNSNSSDSSNSSDSSDS 950
Score = 48.9 bits (115), Expect = 8e-05
Identities = 56/360 (15%), Positives = 132/360 (36%), Gaps = 24/360 (6%)
Query: 414 AQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDD 473
+ SS++ + ++ D + N DS S SSD D +D+ S D +
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 924
Query: 474 AAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGS------------ 521
+ + S + D+ ++ + N +D S+ DSS + D S
Sbjct: 925 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSN 984
Query: 522 ASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISIN 581
+SD SSDS ++ + + S +S S + S +S+ + S +
Sbjct: 985 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1044
Query: 582 KENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTE--DYSKCAQFMDKRWDKKDNE 639
N S + SD + G +D + +++ D S + D D D+
Sbjct: 1045 SSNSSDSSDSSDS---------SDSSDSSGSSDSSDSSDSSDSSDSSDSSDSS-DSSDSS 1094
Query: 640 EIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETGEKIENNQTDDATHNGDDL 699
E + + + + ++ + ++ ++ D ++ + +++ + D++ + D
Sbjct: 1095 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1154
Query: 700 EAETRRLKKLALQEDGGNENEAKFRRGQPNETSYFDKLKEEIELQKQMNIAELNDLDEAT 759
++ + +++ NE+S + + + ++ +D ++T
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1214
Score = 47.0 bits (110), Expect = 3e-04
Identities = 47/280 (16%), Positives = 113/280 (39%), Gaps = 8/280 (2%)
Query: 442 NEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAI 501
++ DS + SSD D +D S D ++ D++ D S + D + + +
Sbjct: 567 SDSDSSDSNSSSDSDSSD----SDSSDSSDSDSS-DSSNSSDSSDSSDSSDSSDSSDSSD 621
Query: 502 FGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQK 561
+D+ +S+ DSS ++ S S D SSDS ++ + N S +S S
Sbjct: 622 SKSDSSKSE-SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 562 TPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTED 621
+ S S+ + S + N S + SD + + N +D + N+ D
Sbjct: 681 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS-NSSD 739
Query: 622 YSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETG 681
S + D + D+ + + + + + ++ + ++ +++D + ++
Sbjct: 740 SSDSSDSSDSS-NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798
Query: 682 EKIENNQTDDATHNGDDLEAETRRLKKLALQEDGGNENEA 721
+++ + D++ + D ++++ + D + + +
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Score = 47.0 bits (110), Expect = 3e-04
Identities = 45/274 (16%), Positives = 108/274 (38%), Gaps = 8/274 (2%)
Query: 431 EQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIE 490
E D T + N DS+G + + D + +G G D ++ D++ D S + D +
Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSS-DSSNSSDSSDSSDS 569
Query: 491 FHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDG---ASSDSESLNEEEEDDVMGNVS 547
+ +D+D SD DS ++ ++SD SSDS + + D + S
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSDSS 627
Query: 548 KWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKN 607
K + ++ + +++ + S N N S + SD + +
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSS 687
Query: 608 VRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEE 667
+D + ++ D S ++ D D D++ + + + + + + ++ +
Sbjct: 688 DSSNSSDSS-DSSDSSNSSESSDSS-DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSD 745
Query: 668 NDDVYGDFEDLETGEKIENNQTDDATHNGDDLEA 701
+ D + ++ + ++ + D++ + D ++
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Score = 46.2 bits (108), Expect = 5e-04
Identities = 61/378 (16%), Positives = 137/378 (36%), Gaps = 18/378 (4%)
Query: 359 NINDHFVQFTKVDDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSE 418
N +D D ++SD + + D S + ++S + + SS+
Sbjct: 893 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 952
Query: 419 ALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQ-DEADAMTGSGLPDQAEDDAAGD 477
+ + +N + ++ + N DS S SSD D +D+ S D + + D
Sbjct: 953 SSNSSDSSNSG-DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1011
Query: 478 KSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEE 537
S + D ++ + + +D SD DSS + + S S D SSDS ++
Sbjct: 1012 SSDSSD------SSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDS 1063
Query: 538 EEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFF 597
+ S +S S + S S + S + ++ S D D
Sbjct: 1064 SGSSDSSDSSDSSDSSDSSDSSDSSDS--------SDSSESSDSSDSSDSSDSSDSSDSS 1115
Query: 598 EPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRN 657
+ + + D N + + S + D D+ + + + + + ++ +
Sbjct: 1116 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 658 GLPKATTEEENDDVYGDFEDLETGEKIENNQTDDATHNGDDLEAETRRLKKLALQEDGGN 717
++ E+ D + ++ +++ + D++ + D E+ K + G+
Sbjct: 1176 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1235
Query: 718 ENEAKFRRGQPNETSYFD 735
++++ N ++ D
Sbjct: 1236 DSDSDSEGSDSNHSTSDD 1253
Score = 37.4 bits (85), Expect = 0.24
Identities = 51/280 (18%), Positives = 110/280 (39%), Gaps = 26/280 (9%)
Query: 422 EAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTN 481
+ QG +++E G S+ GS+S+ D D+ Q +D + D+S
Sbjct: 415 KTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNS-DGYDSYDFDDKSMQGDDPNSSDESNG 473
Query: 482 KDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDD 541
D + ++ R G+ + SD +GN GS S DS+S ++ D
Sbjct: 474 NDDANSESDNNSSSR------GDASYNSDESKDNGN--GSDSKGAEDDDSDSTSDTNNSD 525
Query: 542 VMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIE 601
GN + + +++ S K S S + + +DSS+ +SD
Sbjct: 526 SNGNGNNGNDD-NDKSDSGKGKS------DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578
Query: 602 EVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPK 661
+ + D + + ++ D S + D D D+ + + + ++ K
Sbjct: 579 DSDSSD-SDSSDSSDSDSSDSSNSSDSSDSS-DSSDSSDSSD--------SSDSKSDSSK 628
Query: 662 ATTEEENDDVYGDFEDLETGEKIENNQTDDATHNGDDLEA 701
+ ++ + D D D + + +N+ + D++++ + ++
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668
Score = 35.8 bits (81), Expect = 0.70
Identities = 72/339 (21%), Positives = 129/339 (37%), Gaps = 52/339 (15%)
Query: 401 INEKLENSMINLFAQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSD---QDE 457
I+ K EN N Q ++ + GA +G + N D G Q++
Sbjct: 124 IHGKEENITANGI-QGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQED 182
Query: 458 ADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSG- 516
+ GS ED+ + N+ + E N +R N ++++ +G
Sbjct: 183 GPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKR-------NGTKEAEVTPGTGE 235
Query: 517 -----NEDGSASDDGASSDSESLNEEEEDDVMG------NVSKWKE------------SL 553
N DGS S +GA D + + ++ED+ G N SK +E S+
Sbjct: 236 DAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSI 295
Query: 554 AERTLSQK--TPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDG 611
+ + S++ P + + E + S ++EN + E++ + IE+ +K N R+
Sbjct: 296 GQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGS---QRIEDTQKLNHRES 352
Query: 612 LNDGNVNTEDYSKCA--QFMDK----RWDKKDNEEIRNRFVTGNLAKA-----ALRNGLP 660
N T++ A + DK + N I GN K + G
Sbjct: 353 KRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKG 412
Query: 661 KATTEEENDDVYGDFEDLETGEKIENNQT-DDATHNGDD 698
T+ E ++ G + E G K+ ++ T D+ +G D
Sbjct: 413 NVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYD 451
>INCE_MOUSE (Q9WU62) Inner centromere protein
Length = 880
Score = 55.5 bits (132), Expect = 9e-07
Identities = 38/129 (29%), Positives = 72/129 (55%), Gaps = 7/129 (5%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
K+ K+IE+K + + ++ +ERL +K K T K+ + + +R+Q E R
Sbjct: 567 KEEKKKQIEQKFAQIDEKT-EKAKEERLAEKAKKKATAKKMEEVEARRKQ-----EEEAR 620
Query: 1104 KVLALVQHIQLINHDKMKKRKLKEN-EKRKAHEAEKAKEEQLSKKRRREERREKYRTQDK 1162
++ L Q + H +M +RK +E E+RKA EA + E++ ++RR +ERRE+ R + +
Sbjct: 621 RLRWLQQEEEERRHQEMLQRKKEEEQERRKAAEARRLAEQREQERRREQERREQERREQE 680
Query: 1163 SSKKMRRSE 1171
++ R+ +
Sbjct: 681 RREQERKEQ 689
Score = 39.7 bits (91), Expect = 0.048
Identities = 30/112 (26%), Positives = 64/112 (56%), Gaps = 13/112 (11%)
Query: 1068 QERLPFASKPKETPKRNQPLLEQ--RRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKL 1125
++RL + +E +R + +E+ RR+ V RE ++ ++Q + + ++MK+ K
Sbjct: 514 RQRLESLRRKEEAEQRRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV--EQMKEEKK 571
Query: 1126 KENEKRKAH---EAEKAKEEQLSKKRRRE------ERREKYRTQDKSSKKMR 1168
K+ E++ A + EKAKEE+L++K +++ E E R Q++ ++++R
Sbjct: 572 KQIEQKFAQIDEKTEKAKEERLAEKAKKKATAKKMEEVEARRKQEEEARRLR 623
Score = 32.7 bits (73), Expect = 5.9
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 14/132 (10%)
Query: 1043 NKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRE 1102
+++ L +K E + + R ++R + +E ++ + E+R Q+ E RE
Sbjct: 634 HQEMLQRKKEEEQERRKAAEARRLAEQREQERRREQERREQERREQERREQERKEQERRE 693
Query: 1103 RKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREE--RREKYRTQ 1160
++ L KR+++E EK + E+ ++E L +K+R+EE R + + Q
Sbjct: 694 QEQERL-----------RAKREMQEREKALRLQKERLQKE-LEEKKRKEEQQRLAEQQLQ 741
Query: 1161 DKSSKKMRRSEA 1172
++ +KK + A
Sbjct: 742 EEQAKKAKEVAA 753
>SR40_YEAST (P32583) Suppressor protein SRP40
Length = 406
Score = 52.8 bits (125), Expect = 6e-06
Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 20/198 (10%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDV 430
+ E+ D T+K E +ETK E +S + S + +E++ +
Sbjct: 119 ESESEDETKKRARESDNE----DAKETKKAKTEPESSSSSESSSSGSSSSSESESGS--- 171
Query: 431 EQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIE 490
E D + + + DS+ SES Q + + + D D ++ D S++ D
Sbjct: 172 ESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDS--DSSSSDSSSDSDSSSSSSS 229
Query: 491 FHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVS--- 547
+ +D+D S DSSG+ D S+S D +S +S S + + D + S
Sbjct: 230 SSSDS-------DSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSE 282
Query: 548 -KWKESLAERTLSQKTPS 564
+ KE+ A+ + +++TP+
Sbjct: 283 LETKEATADESKAEETPA 300
Score = 52.0 bits (123), Expect = 9e-06
Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 4/155 (2%)
Query: 445 DSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNK----DHLEEHIEFHNGRRRRRA 500
DS+ SES + + S D++ ++ + T K E+ E + +
Sbjct: 91 DSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKKAKTEPES 150
Query: 501 IFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQ 560
+++ S SS +E GS SD +SS S S ++ E D + S S ++ +
Sbjct: 151 SSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDS 210
Query: 561 KTPSLMQLVYGESTVNLISINKENDSSEDEESDGD 595
+ S +S+ + S + ++DS D SD D
Sbjct: 211 DSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSD 245
Score = 43.9 bits (102), Expect = 0.003
Identities = 51/305 (16%), Positives = 118/305 (37%), Gaps = 12/305 (3%)
Query: 428 MDVEQDGIIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEE 487
+ V++ I E + + S S SS + + + + ++ S + D +
Sbjct: 14 LSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDS 73
Query: 488 HIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVS 547
+ + +D++ S DSS + GS+S +SSD S E ED+
Sbjct: 74 ESSSSSSSSSSSSSSSSDSESSSESDSSSS--GSSSSSSSSSDESSSESESEDETKKRAR 131
Query: 548 KWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKN 607
+ A+ T KT ES+ + S + + SS + ES G + +
Sbjct: 132 ESDNEDAKETKKAKTEP-------ESSSSSESSSSGSSSSSESES-GSESDSDSSSSSSS 183
Query: 608 VRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEE 667
D +D +++ S + D D D+ + + + + ++ + + ++
Sbjct: 184 SSDSESDSESDSQS-SSSSSSSDSSSD-SDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSS 241
Query: 668 NDDVYGDFEDLETGEKIENNQTDDATHNGDDLEAETRRLKKLALQEDGGNENEAKFRRGQ 727
+D D + ++++ + + D ++++ +L +E +E++A+
Sbjct: 242 SDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPAS 301
Query: 728 PNETS 732
NE++
Sbjct: 302 SNEST 306
Score = 35.8 bits (81), Expect = 0.70
Identities = 25/123 (20%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 414 AQSSEALAEAQGANMDVEQDG-IIETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAED 472
+ SS++ +++ ++ D D + + + DSD S+SS ++ + S +
Sbjct: 201 SSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSS----SSS 256
Query: 473 DAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSE 532
D++ D+ST+ D + + +G AD+S ++ + + S +SS +
Sbjct: 257 DSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSSSSAN 316
Query: 533 SLN 535
LN
Sbjct: 317 KLN 319
>ITN1_MOUSE (Q9Z0R4) Intersectin 1 (EH and SH3 domains protein 1)
Length = 1714
Score = 51.2 bits (121), Expect = 2e-05
Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 27/179 (15%)
Query: 996 FLRAWTQVEVPQFYNPLTTALQP--------RDQTWKGMRTVAELRRDHDLPVPVNKDSL 1047
F+ A ++V PL L P R ++ GM ++ D LP + +
Sbjct: 279 FILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSVDQRLPEEPSSED- 337
Query: 1048 YKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLA 1107
E++P K P+ F K +E +R LE+RRQ + + +E++ LA
Sbjct: 338 ----EQQPEKKLPVT----------FEDKKRENFERGSVELEKRRQALLEQQRKEQERLA 383
Query: 1108 LVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKK 1166
++ + + K+R+ +E E ++ E EK E+Q +R+REE R K + +++K+
Sbjct: 384 QLERAE----QERKERERQEQEAKRQLELEKQLEKQRELERQREEERRKEIERREAAKR 438
>DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin
matrix protein-3) (DMP-3) [Contains: Dentin
phosphoprotein (Dentin phosphophoryn) (DPP); Dentin
sialoprotein (DSP)]
Length = 934
Score = 50.4 bits (119), Expect = 3e-05
Identities = 38/183 (20%), Positives = 76/183 (40%), Gaps = 1/183 (0%)
Query: 414 AQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQ-DEADAMTGSGLPDQAED 472
+ SS++ + ++ D + + + DS S+SSD D +D+ S D ++
Sbjct: 741 SDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 800
Query: 473 DAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSE 532
+ D S + + + + + + +D SD DSS + D S S D + S
Sbjct: 801 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 860
Query: 533 SLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEES 592
S + + D + S + ++ + S S G+S + + +DS+ D +S
Sbjct: 861 SDSSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDSKSGNGNSDSNSDSNSDSDS 920
Query: 593 DGD 595
D +
Sbjct: 921 DSE 923
Score = 50.1 bits (118), Expect = 4e-05
Identities = 50/286 (17%), Positives = 111/286 (38%), Gaps = 7/286 (2%)
Query: 417 SEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQ-DEADAMTGSGLPDQAEDDAA 475
SE E+ ++ D D E+ + + SD S+SSD D +D+ S D ++ +
Sbjct: 525 SEDKDESDSSDHDNSSDS--ESKSDSSDSSDDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 582
Query: 476 GDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGA----SSDS 531
D +++ D + + + +D SD DSS + D S S D + SSDS
Sbjct: 583 SDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 642
Query: 532 ESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEE 591
S ++ + + S +S S + S S + S + ++ SS D
Sbjct: 643 SSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDSSDSSDSSSSSDSS 702
Query: 592 SDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLA 651
D + + + D + ++ S + D D+ + + + + +
Sbjct: 703 DSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSDSSESSDSS 762
Query: 652 KAALRNGLPKATTEEENDDVYGDFEDLETGEKIENNQTDDATHNGD 697
++ + ++ ++ D + ++ +++ + D++ + D
Sbjct: 763 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 808
Score = 49.3 bits (116), Expect = 6e-05
Identities = 51/255 (20%), Positives = 103/255 (40%), Gaps = 14/255 (5%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDV 430
D +SD + N D + S ++ ++S + + SS++ A + ++
Sbjct: 674 DSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSD 733
Query: 431 EQDGIIETVNYNEMDSDGGSESSDQDEA-DAMTGSGLPDQAEDDAAGDKSTNKDHLEEHI 489
D + + + DS S+SSD E+ D+ S D ++ + D S + D +
Sbjct: 734 SSDS---SSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 790
Query: 490 EFHNGRRRRRAIFGNDADQSDLMDSSGNEDGS-ASDDGASSDSESLNEEEEDDVMGNVSK 548
++ + +D SD DSS + D S +SD SSDS ++ + + S
Sbjct: 791 SSNSSDS------SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 844
Query: 549 WKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNV 608
+S S + S +S+ + S + + S+ + SD D + + +
Sbjct: 845 SSDSSDSSDSSDSSDSSDS---SDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDS 901
Query: 609 RDGLNDGNVNTEDYS 623
+ G + + N++ S
Sbjct: 902 KSGNGNSDSNSDSNS 916
Score = 48.1 bits (113), Expect = 1e-04
Identities = 43/260 (16%), Positives = 106/260 (40%), Gaps = 16/260 (6%)
Query: 442 NEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAI 501
++ + DG SES D+DE+D+ S + ++ ++ D S + D + + + +
Sbjct: 515 SDSNGDGDSESEDKDESDS---SDHDNSSDSESKSDSSDSSDDSSDSSDSSDS-----SD 566
Query: 502 FGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQK 561
+ +D SD DSS + D ++S D + S S + + D + S ++ + S
Sbjct: 567 SSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSD 626
Query: 562 TPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTED 621
+ S + S + ++ SS D + + + D + + ++ D
Sbjct: 627 SSD-------SSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSD 679
Query: 622 YSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETG 681
S + D D D+ + + + + ++ +G ++ + D + ++
Sbjct: 680 SSSSSNSSDSS-DSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSS 738
Query: 682 EKIENNQTDDATHNGDDLEA 701
+++ + D++ + D E+
Sbjct: 739 SSSDSSDSSDSSDSSDSSES 758
Score = 43.1 bits (100), Expect = 0.004
Identities = 45/256 (17%), Positives = 100/256 (38%), Gaps = 25/256 (9%)
Query: 452 SSDQDEADAMTGSGLPDQAEDD------AAGDKSTNKDHLEEHIEFHNGRRRRRAIFGND 505
S Q E+D G+ A + + S D E E G + + N
Sbjct: 403 SPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQGDDPKSSDESNG 462
Query: 506 ADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSL 565
+D+SD S NE GS D +SD S ++ + D G +S +
Sbjct: 463 SDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSGD---------- 512
Query: 566 MQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKC 625
G+S N + +++S + +ESD + + + K+ +D + ++ D S
Sbjct: 513 -----GDSDSN---GDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDS 564
Query: 626 AQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETGEKIE 685
+ D D D+ + + + + + ++ +G ++ + D + ++ + +
Sbjct: 565 SDSSDSS-DSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSD 623
Query: 686 NNQTDDATHNGDDLEA 701
++ + D++ + D ++
Sbjct: 624 SSDSSDSSDSSDSSDS 639
Score = 40.8 bits (94), Expect = 0.022
Identities = 84/395 (21%), Positives = 152/395 (38%), Gaps = 60/395 (15%)
Query: 378 TRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQSSEALAE----AQGANMDVEQD 433
T+ G D+ + +L + P ++NS + +A Q + E
Sbjct: 161 TKSGGASDVSQNGDATLVQENEPPEASIKNSTNHEAGIHGSGVATHETTPQREGLGSENQ 220
Query: 434 GIIETVNYNE---MDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLE-EHI 489
G T + E +D GS S + E D TGSG + AE AGD + D + +
Sbjct: 221 GTEVTPSIGEDAGLDDTDGSPSGNGVEEDEDTGSGDGEGAE---AGDGRESHDGTKGQGG 277
Query: 490 EFHNGRRRRRAIFGNDADQSDLMDSSG-----NEDGSASDDG--------ASSDSESLNE 536
+ H G R + D + G N D S+ ++G A+ D E L+
Sbjct: 278 QSHGGNTDHRGQSSVSTEDDDSKEQEGFPNGHNGDNSSEENGVEEGDSTQATQDKEKLSP 337
Query: 537 EEEDDVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDS-SEDEESDGD 595
++ D G + S +E S K+ G + N I KE+ S ++S+G
Sbjct: 338 KDTRDAEGGII----SQSEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSNGH 393
Query: 596 FFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFM-------DKRWDKKDNEEIRNRFVTG 648
+ +E K+ + + G +D T + S + D D+ E + + G
Sbjct: 394 --QGVELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQG 451
Query: 649 NLAKAALR-NGLPKATTEEEN-------------DDVYGDFEDLETGEKIENNQTDDATH 694
+ K++ NG ++ T E+ D D ++ E++ +DD++
Sbjct: 452 DDPKSSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSG 511
Query: 695 NGD-------DLEAETRRLKKLALQEDGGNENEAK 722
+GD D E+E + + + D +++E+K
Sbjct: 512 DGDSDSNGDGDSESEDKD-ESDSSDHDNSSDSESK 545
Score = 36.2 bits (82), Expect = 0.54
Identities = 33/142 (23%), Positives = 56/142 (39%), Gaps = 19/142 (13%)
Query: 414 AQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSD-QDEADAMTGSGLPDQAED 472
+ SS + + ++ D + + + DS S+SSD D +D+ S D ++
Sbjct: 807 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 866
Query: 473 DAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSG-NEDGSASDDGASSDS 531
+ D S + D +D+ SD DSS + DG + +SDS
Sbjct: 867 SDSSDSSDSSDSSN----------------SSDSSDSDSKDSSSDSSDGDSKSGNGNSDS 910
Query: 532 ES-LNEEEEDDVMGNVSKWKES 552
S N + + D G+ S S
Sbjct: 911 NSDSNSDSDSDSEGSDSNHSTS 932
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 50.4 bits (119), Expect = 3e-05
Identities = 58/284 (20%), Positives = 123/284 (42%), Gaps = 32/284 (11%)
Query: 450 SESSDQDEADAMTGS-GLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQ 508
SE SD+DE + GL +A KS ++ E+ E +++ + + +++
Sbjct: 183 SEESDEDEKPSKKSKKGLKKKA-------KSESESESEDEKEVKKSKKKSKKVVKKESES 235
Query: 509 SDLMDSSGNEDG---SASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLS---QKT 562
D + S + SS+SE +EEEE+ K K+ LA + LS +
Sbjct: 236 EDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESE 295
Query: 563 PSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDY 622
S ++++ + +++ +++ +D++S+ + + E+V KK + + + + D
Sbjct: 296 ESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKK--QESSESGSDS 353
Query: 623 SKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEENDDVYGDFEDLETGE 682
S+ + ++++ KK+ E + + + + +K L K T + E + E + E
Sbjct: 354 SEGSITVNRKSKKKEKPEKKKKGIIMDSSK------LQKETIDAER----AEKERRKRLE 403
Query: 683 KIENNQTDDATHNGDDL------EAETRRLKKLALQEDGGNENE 720
K + G+DL + R+LK + L D +E
Sbjct: 404 KKQKEFNGIVLEEGEDLTEMLTGTSSQRKLKSVVLDPDSSTVDE 447
Score = 45.1 bits (105), Expect = 0.001
Identities = 61/323 (18%), Positives = 128/323 (38%), Gaps = 42/323 (13%)
Query: 448 GGSESSDQD-----EADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIF 502
G SES D D + D + ++ ++ A ++ + ++R+A
Sbjct: 4 GVSESEDSDGHVIEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASS 63
Query: 503 GNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKT 562
+ D + + S + S A S+SES +EE+D + SK K ++ S+K
Sbjct: 64 SEEDDDDE--EESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKK- 120
Query: 563 PSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDY 622
+ SSEDE+SD + + ++ KK + ++ + +E+
Sbjct: 121 ------------------KRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEE 162
Query: 623 SKCAQFMDKRWDKKDNEEIRNRFVTGNLA------KAALRNGL---PKATTEEENDDVYG 673
K K+ K + ++ R T + + GL K+ +E E++D
Sbjct: 163 RKV-----KKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKE 217
Query: 674 DFEDLETGEKIENNQTDDATHNGDDLEAETRRLKKLALQEDGGNENEAKFRRGQPNETSY 733
+ + +K+ +++ + + E R+ K + +E +E+E + E+S
Sbjct: 218 VKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEE--SSESEKSDEEEEEKESSP 275
Query: 734 FDKLKEEIELQKQMNIAELNDLD 756
K K+ + ++K + E + D
Sbjct: 276 KPKKKKPLAVKKLSSDEESEESD 298
Score = 32.7 bits (73), Expect = 5.9
Identities = 21/96 (21%), Positives = 49/96 (50%), Gaps = 5/96 (5%)
Query: 1078 KETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAH--- 1134
K+T + E+ R+ + +E+ V + + + D+ +K K+ K+KA
Sbjct: 149 KQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSES 208
Query: 1135 --EAEKAKEEQLSKKRRREERREKYRTQDKSSKKMR 1168
E+E KE + SKK+ ++ +++ ++D++ +K +
Sbjct: 209 ESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKK 244
>ITN1_RAT (Q9WVE9) Intersectin 1 (EH domain and SH3 domain regulator
of endocytosis 1)
Length = 1217
Score = 50.1 bits (118), Expect = 4e-05
Identities = 45/182 (24%), Positives = 85/182 (45%), Gaps = 33/182 (18%)
Query: 996 FLRAWTQVEVPQFYNPLTTALQP--------RDQTWKGMRTVAELRRDHDLPV-PVNKDS 1046
F+ A ++V PL L P R ++ GM ++ D LP P ++D
Sbjct: 279 FILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSADQRLPEEPSSEDE 338
Query: 1047 LYKKIERKPRKFNPLVVPRSLQERLP--FASKPKETPKRNQPLLEQRRQKGVVMEPRERK 1104
+ ++++LP F K +E +R LE+RRQ + + +E++
Sbjct: 339 ------------------QQVEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQE 380
Query: 1105 VLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSS 1164
LA ++ + + K+R+ +E E+++ E EK E+Q +R+REE R K + +++
Sbjct: 381 RLAQLERAE----QERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAA 436
Query: 1165 KK 1166
K+
Sbjct: 437 KR 438
Score = 34.7 bits (78), Expect = 1.6
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 13/111 (11%)
Query: 1067 LQERLPFASKPKETPK--RNQPLLEQR--RQKGVVMEPRERKVLALVQHIQ-----LINH 1117
LQE F ++ KE + Q L +QR + + + +ERK L L + + +
Sbjct: 596 LQEIDVFNNQLKELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQER 655
Query: 1118 DKMKKRKLKENEK---RKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSK 1165
DK + +++ E+ RK HE +K K E KK+ EE R K QDK S+
Sbjct: 656 DKQWQEHVQQEEQQRPRKPHEEDKLKREDSVKKKEAEE-RAKPEVQDKQSR 705
>ITN1_HUMAN (Q15811) Intersectin 1 (SH3 domain-containing protein 1A)
(SH3P17)
Length = 1721
Score = 50.1 bits (118), Expect = 4e-05
Identities = 46/182 (25%), Positives = 85/182 (46%), Gaps = 32/182 (17%)
Query: 996 FLRAWTQVEVPQFYNPLTTALQP--------RDQTWKGMRTVAELRRDHDLPV-PVNKDS 1046
F+ A ++V PL L P R ++ G+ ++ D LP PV +D
Sbjct: 279 FILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDE 338
Query: 1047 LYKKIERKPRKFNPLVVPRSLQERLP--FASKPKETPKRNQPLLEQRRQKGVVMEPRERK 1104
+ L+++LP F K +E +R LE+RRQ + + +E++
Sbjct: 339 -----------------QQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQE 381
Query: 1105 VLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSS 1164
LA ++ + + K+R+ +E E+++ E EK E+Q +R+REE R K + +++
Sbjct: 382 RLAQLERAE----QERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAA 437
Query: 1165 KK 1166
K+
Sbjct: 438 KR 439
Score = 33.9 bits (76), Expect = 2.7
Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 1065 RSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRK 1124
+ LQ++ ++ + ++ + ++E +QK + + ++H+Q ++
Sbjct: 617 QQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQ---------QE 667
Query: 1125 LKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDK 1162
+ RK HE EK K E+ KK+ EE + K QDK
Sbjct: 668 DEHQRPRKLHEEEKLKREESVKKKDGEE-KGKQEAQDK 704
>ATRX_RAT (P70486) Transcriptional regulator ATRX (X-linked nuclear
protein) (pABP-2) (Fragment)
Length = 527
Score = 50.1 bits (118), Expect = 4e-05
Identities = 64/302 (21%), Positives = 124/302 (40%), Gaps = 39/302 (12%)
Query: 450 SESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQS 509
S +S + + +GS D AE + K K + + N + R+R +
Sbjct: 239 SSNSKRSTKEVKSGSSSSD-AEGSSEDAKKQKKQRMSAKKKNSNTKERKRKSLRATTTKR 297
Query: 510 DLMDSSGNEDGSASDDGASSDSESLNEEE-----EDDVMGNVSKWKESLAERTLSQKTPS 564
D + + DD S+ ES +E++ E+ V+ + + + +S + S+ P+
Sbjct: 298 KQADITSSSSDIGDDDQNSAGEESSDEQKIKPVTENLVLPSHTGFCQSSGDEAFSKSVPA 357
Query: 565 LM---------------QLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVR 609
+ +++ E NL S E+ SS+DE +G+ ++ ++
Sbjct: 358 TVDDDDDDNDPENRIAKKMLLEEIKANLSS--DEDGSSDDEPKEGEKKRIGKQSEETPGD 415
Query: 610 DGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKATTEEEND 669
DG N VN+E S + R+ R+R + L+ + +G K T +E+
Sbjct: 416 DGSN--QVNSESDSDSEESKKPRY--------RHRLLRHKLSLSDGESGGEKKTKPKEHK 465
Query: 670 DVYG------DFEDLETGEKIENNQTDDATHNGDDLEAETRRLKKLALQEDGGNENEAKF 723
+ G ED E + E+ +++ + + D+ TR KK L+E+ + + K
Sbjct: 466 ETKGRNRRKVSSEDSEDTDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 525
Query: 724 RR 725
RR
Sbjct: 526 RR 527
>ITN1_XENLA (O42287) Intersectin 1
Length = 1270
Score = 48.5 bits (114), Expect = 1e-04
Identities = 29/105 (27%), Positives = 61/105 (57%), Gaps = 6/105 (5%)
Query: 1064 PRSLQERLP--FASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMK 1121
P++ ++LP F K +E +R LE+RRQ + + +E++ LA ++ + + K
Sbjct: 337 PQNADKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE----QERK 392
Query: 1122 KRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKK 1166
+R+ ++ E+++ + EK E+Q +R+REE R K + +++K+
Sbjct: 393 ERERQDQERKRQQDLEKQLEKQRELERQREEERRKEIERREAAKR 437
>TRHY_RABIT (P37709) Trichohyalin
Length = 1407
Score = 47.8 bits (112), Expect = 2e-04
Identities = 38/161 (23%), Positives = 81/161 (49%), Gaps = 8/161 (4%)
Query: 1017 QPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASK 1076
Q RD+ + + + + L + L ++ +RK R+ L+ R +ERL +
Sbjct: 736 QERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREEEQLLQERE-EERLRRQER 794
Query: 1077 PKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKK----RKLKENEKRK 1132
++ + Q LL++R ++ + + RERK+ Q +Q +++++ RKL+E E+
Sbjct: 795 ERKLREEEQ-LLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLL 853
Query: 1133 AHEAEKAKEEQLSKKRRREE--RREKYRTQDKSSKKMRRSE 1171
E ++ ++E+ K R E+ R+E+ + + +K+R E
Sbjct: 854 RQEEQELRQERARKLREEEQLLRQEEQELRQERDRKLREEE 894
Score = 45.4 bits (106), Expect = 9e-04
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 36/191 (18%)
Query: 1017 QPRDQTWKGMRTVAELR----RDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLP 1072
+PR Q + +R E R R+ +L + ++ E R+ L SL+ER
Sbjct: 394 RPRRQEEQSLRQDQERRQRQERERELEEQARRQQQWQAEEESERRRQRLSARPSLRERQL 453
Query: 1073 FASKPKETPKRNQPLLEQRRQKGVVMEPRE-------RKVLALVQHIQLINHDKMKKRK- 1124
A + +E +R + EQRR++ ++ E R+ +Q D+ ++R+
Sbjct: 454 RAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDRERRRRQ 513
Query: 1125 ------------LKENEKRKAH--------EAEKAKEEQLSKKRRREERREKYRTQDK-- 1162
L+E +R+ H + + +EE+L +++RR+ER +YR ++K
Sbjct: 514 QEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYREEEKLQ 573
Query: 1163 --SSKKMRRSE 1171
+K RR E
Sbjct: 574 REEDEKRRRQE 584
Score = 45.1 bits (105), Expect = 0.001
Identities = 31/127 (24%), Positives = 67/127 (52%), Gaps = 2/127 (1%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
+ L ++ +RK R+ L+ R +ERL + ++ + + LL + +++ + + R+R
Sbjct: 1249 EQELRRERDRKFREEEQLLQERE-EERLRRQERARKLREEEEQLLFEEQEEQRLRQERDR 1307
Query: 1104 KVLALVQHIQLINHDKMKKRKLKENEKRKAHEAE-KAKEEQLSKKRRREERREKYRTQDK 1162
+ A Q + ++++ +E E+R+ E E K +EEQL +++ E+RR + R +
Sbjct: 1308 RYRAEEQFAREEKSRRLERELRQEEEQRRRRERERKFREEQLRRQQEEEQRRRQLRERQF 1367
Query: 1163 SSKKMRR 1169
+ RR
Sbjct: 1368 REDQSRR 1374
Score = 43.1 bits (100), Expect = 0.004
Identities = 39/138 (28%), Positives = 71/138 (51%), Gaps = 17/138 (12%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
+ L ++ ERK R+ L+ R +ERL + ++ + Q LL Q Q+ + + RER
Sbjct: 663 EQELRQERERKLREEEQLLQERE-EERLRRQERARKLREEEQ-LLRQEEQE--LRQERER 718
Query: 1104 KVLALVQHIQLINHDKM-----KKRKLKENEKRKAHEAEKA-----KEEQLSKKRRREER 1153
K L + QL+ ++ + RKL+E E+ E+ +E+QL ++R R+ R
Sbjct: 719 K---LREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFR 775
Query: 1154 REKYRTQDKSSKKMRRSE 1171
E+ Q++ +++RR E
Sbjct: 776 EEEQLLQEREEERLRRQE 793
Score = 42.0 bits (97), Expect = 0.010
Identities = 31/120 (25%), Positives = 62/120 (50%), Gaps = 10/120 (8%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQH 1111
ERK R+ L+ + R A K +E + LL++R ++ + + R RK L +
Sbjct: 933 ERKLREEEQLLRREEQELRRERARKLRE----EEQLLQEREEERLRRQERARK---LREE 985
Query: 1112 IQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
QL+ ++ ++L++ RK E E+ +E+ ++ RR+ER K+R +++ ++ E
Sbjct: 986 EQLLRREE---QELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEE 1042
Score = 42.0 bits (97), Expect = 0.010
Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 21/166 (12%)
Query: 1016 LQPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFAS 1075
LQ R++ + A R+ + + + L ++ +RK R+ L+ R +ERL
Sbjct: 965 LQEREEERLRRQERARKLREEEQLLRREEQELRQERDRKFREEEQLLQERE-EERLRRQE 1023
Query: 1076 KPK-----ETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEK 1130
+ + E R Q L EQ RQ+ R+RK Q I +K +K+ ++
Sbjct: 1024 RDRKFREEERQLRRQELEEQFRQE------RDRKFRLEEQ----IRQEKEEKQLRRQERD 1073
Query: 1131 RKAHEAEKAK-----EEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
RK E E+ + E+QL ++R R+ R E+ Q++ +++RR E
Sbjct: 1074 RKFREEEQQRRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQE 1119
Score = 40.4 bits (93), Expect = 0.028
Identities = 38/144 (26%), Positives = 72/144 (49%), Gaps = 22/144 (15%)
Query: 1019 RDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPK 1078
R + + R + ELR++ L +RK R+ L+ R +ERL + +
Sbjct: 582 RQERERQYRELEELRQEEQLR------------DRKLREEEQLLQERE-EERLRRQERER 628
Query: 1079 ETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEK 1138
+ + Q LL Q Q+ + + RERK L + QL+ ++ ++L++ +RK E E+
Sbjct: 629 KLREEEQ-LLRQEEQE--LRQERERK---LREEEQLLRREE---QELRQERERKLREEEQ 679
Query: 1139 AKEEQLSKKRRREERREKYRTQDK 1162
+E+ ++ RR+ER K R +++
Sbjct: 680 LLQEREEERLRRQERARKLREEEQ 703
Score = 39.7 bits (91), Expect = 0.048
Identities = 43/178 (24%), Positives = 86/178 (48%), Gaps = 27/178 (15%)
Query: 1016 LQPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFAS 1075
LQ R++ + A R+ + + + L ++ +RK R+ L+ S +ERL
Sbjct: 1107 LQEREEERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEEQLL-QESEEERLRRQE 1165
Query: 1076 KPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKM-----KKRKLKENEK 1130
+ ++ + Q LL++R ++ + + R RK L + QL+ ++ + RKL+E E+
Sbjct: 1166 RERKLREEEQ-LLQEREEERLRRQERARK---LREEEQLLRQEEQELRQERARKLREEEQ 1221
Query: 1131 ---------RKAHEAEKAKEEQLSKKRRREERREKYR--------TQDKSSKKMRRSE 1171
R+ + + +EEQL ++ +E RRE+ R Q++ +++RR E
Sbjct: 1222 LLRQEEQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQE 1279
Score = 39.7 bits (91), Expect = 0.048
Identities = 33/126 (26%), Positives = 63/126 (49%), Gaps = 12/126 (9%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQH 1111
ERK R+ L+ QE + + + + LL RR++ + + RERK+ Q
Sbjct: 627 ERKLREEEQLL----RQEEQELRQERERKLREEEQLL--RREEQELRQERERKLREEEQL 680
Query: 1112 IQLINHDKMKK----RKLKENEKRKAHEAEKAKEEQLSKKRRREE--RREKYRTQDKSSK 1165
+Q +++++ RKL+E E+ E ++ ++E+ K R E+ RRE+ + + +
Sbjct: 681 LQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDR 740
Query: 1166 KMRRSE 1171
K+R E
Sbjct: 741 KLREEE 746
Score = 39.3 bits (90), Expect = 0.063
Identities = 34/148 (22%), Positives = 70/148 (46%), Gaps = 24/148 (16%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
+ L ++ RK R+ L+ R +ERL + ++ + Q L RR++ + + R+R
Sbjct: 947 EQELRRERARKLREEEQLLQERE-EERLRRQERARKLREEEQLL---RREEQELRQERDR 1002
Query: 1104 KVLALVQHIQLINHDKMKK----RKLKENEK----------------RKAHEAEKAKEEQ 1143
K Q +Q +++++ RK +E E+ RK E+ ++E+
Sbjct: 1003 KFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEK 1062
Query: 1144 LSKKRRREERREKYRTQDKSSKKMRRSE 1171
K+ RR+ER K+R +++ ++ R +
Sbjct: 1063 EEKQLRRQERDRKFREEEQQRRRQEREQ 1090
Score = 38.9 bits (89), Expect = 0.083
Identities = 36/143 (25%), Positives = 72/143 (50%), Gaps = 19/143 (13%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
+ L ++ +RK R+ L+ R +ERL + ++ + Q L RR++ ++ + R+R
Sbjct: 1089 EQQLRRERDRKFREEEQLLQERE-EERLRRQERARKLREEEQLL---RREEQLLRQERDR 1144
Query: 1104 KVLALVQHIQLINHDKMKK----RKLKENEK----------RKAHEAEKAKEE-QLSKKR 1148
K Q +Q +++++ RKL+E E+ R+ A K +EE QL ++
Sbjct: 1145 KFREEEQLLQESEEERLRRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQE 1204
Query: 1149 RREERREKYRTQDKSSKKMRRSE 1171
+E R+E+ R + + +R+ E
Sbjct: 1205 EQELRQERARKLREEEQLLRQEE 1227
Score = 38.5 bits (88), Expect = 0.11
Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 1021 QTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKET 1080
QTW+ RR H L + ++ E R+ R +E + E
Sbjct: 520 QTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYREEEKLQREEDEK 579
Query: 1081 PKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAK 1140
+R E+ RQ + E R+ + L + +L +++ + + +E +R+ E + +
Sbjct: 580 RRRQ----ERERQYRELEELRQEEQL---RDRKLREEEQLLQEREEERLRRQERERKLRE 632
Query: 1141 EEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
EEQL ++ +E R+E+ R + + +RR E
Sbjct: 633 EEQLLRQEEQELRQERERKLREEEQLLRREE 663
Score = 38.1 bits (87), Expect = 0.14
Identities = 31/135 (22%), Positives = 65/135 (47%), Gaps = 6/135 (4%)
Query: 1041 PVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPL---LEQRRQKGVV 1097
P + L +++E + L +++L + ++ +R Q L LE+ R++
Sbjct: 253 PREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQQLRRELEEIREREQR 312
Query: 1098 MEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKY 1157
+E ER+ L Q + ++ KR+L+E +R+ ++ + EQL + RE+ RE+
Sbjct: 313 LEQEERREQRLEQEER---REQQLKRELEEIREREQRLEQEERREQLLAEEVREQARERG 369
Query: 1158 RTQDKSSKKMRRSEA 1172
+ + ++ SEA
Sbjct: 370 ESLTRRWQRQLESEA 384
Score = 37.4 bits (85), Expect = 0.24
Identities = 17/91 (18%), Positives = 51/91 (55%)
Query: 1082 KRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKE 1141
+ + LL++R ++ + + RERK+ Q +Q +++++++ + + + ++ +E
Sbjct: 775 REEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLQEREE 834
Query: 1142 EQLSKKRRREERREKYRTQDKSSKKMRRSEA 1172
E+L ++ R + RE+ + + +++R+ A
Sbjct: 835 ERLRRQERERKLREEEQLLRQEEQELRQERA 865
Score = 37.4 bits (85), Expect = 0.24
Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 33/144 (22%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQH 1111
ERK R+ L+ + R A K +E + LL Q Q+ + + R+RK L +
Sbjct: 843 ERKLREEEQLLRQEEQELRQERARKLRE----EEQLLRQEEQE--LRQERDRK---LREE 893
Query: 1112 IQLINHDKM-----KKRKLKENE-----------KRKAHEAEKAKEEQLSKKRRREERRE 1155
QL+ ++ + RKL+E E +R+ E + +EEQL ++ +E RRE
Sbjct: 894 EQLLRQEEQELRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRE 953
Query: 1156 KYR--------TQDKSSKKMRRSE 1171
+ R Q++ +++RR E
Sbjct: 954 RARKLREEEQLLQEREEERLRRQE 977
Score = 37.0 bits (84), Expect = 0.31
Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 1068 QERLPFASKPKETPKRNQPL---LEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRK 1124
+E+L + +E P+ Q L LE+ R++ +E ER+ L + +L ++ +++
Sbjct: 240 EEQLLRQRRWREEPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQQL 299
Query: 1125 LKENEKRKAHEAEKAKEEQLSKKRRREERREK 1156
+E E+ + E +EE+ ++ +EERRE+
Sbjct: 300 RRELEEIREREQRLEQEERREQRLEQEERREQ 331
Score = 36.6 bits (83), Expect = 0.41
Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 1076 KPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMK-KRKLKENE----- 1129
+ KE + Q L E+R ++ + + R ++ QL ++ + KR+L+E E
Sbjct: 168 RDKEQRLQRQELEERRAEEEQLRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRE 227
Query: 1130 KRKAHE-AEKAKEEQLSKKRR-REERREKYRTQDKSSKKMRRSE 1171
+R+ HE A + +EEQL ++RR REE RE+ + + + + R +
Sbjct: 228 RREQHERALQEEEEQLLRQRRWREEPREQQQLRRELEEIREREQ 271
Score = 35.8 bits (81), Expect = 0.70
Identities = 20/90 (22%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Query: 1082 KRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKE 1141
+ + LL++R ++ + + R RK+ + QL+ ++ ++R +E ++R E + A+E
Sbjct: 1261 REEEQLLQEREEERLRRQERARKLRE--EEEQLLFEEQEEQRLRQERDRRYRAEEQFARE 1318
Query: 1142 EQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
E+ + R + E+ R + + +K R +
Sbjct: 1319 EKSRRLERELRQEEEQRRRRERERKFREEQ 1348
Score = 35.4 bits (80), Expect = 0.91
Identities = 35/161 (21%), Positives = 80/161 (48%), Gaps = 20/161 (12%)
Query: 1027 RTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQP 1086
R ELR++ + + + L ++ E + R+ R +E+L + + +R +
Sbjct: 661 REEQELRQERERKLREEEQLLQEREEERLRRQERARKLRE-EEQLLRQEEQELRQERERK 719
Query: 1087 LLEQ----RRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEE 1142
L E+ RR++ ++ + R+RK+ Q +Q +++++++ +E + R+ + + +EE
Sbjct: 720 LREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQE-REQQLRRERDRKFREEE 778
Query: 1143 QLSKKRRREERR------------EKYRTQDKSSKKMRRSE 1171
QL ++R EE R E+ Q++ +++RR E
Sbjct: 779 QLLQER--EEERLRRQERERKLREEEQLLQEREEERLRRQE 817
Score = 35.4 bits (80), Expect = 0.91
Identities = 29/117 (24%), Positives = 57/117 (47%), Gaps = 11/117 (9%)
Query: 1065 RSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALV----QHIQLINHDKM 1120
+ LQE F + +E +R Q + + + E +R+ L Q QL +++
Sbjct: 495 QQLQEEDSF-QEDRERRRRQQEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEEL 553
Query: 1121 KKRKLKENEKRKAHEAEKAKEEQLSKKRRREERR-----EKYRTQDK-SSKKMRRSE 1171
++ K ++ +R+ E EK + E+ K+RR+E R E+ R +++ +K+R E
Sbjct: 554 QREKRRQEREREYREEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDRKLREEE 610
Score = 33.1 bits (74), Expect = 4.5
Identities = 22/96 (22%), Positives = 50/96 (51%), Gaps = 4/96 (4%)
Query: 1078 KETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAE 1137
+E + + L E+ +Q+ E ER + + QL+ + ++ ++ + R+ E
Sbjct: 209 REQQELKRELREEEQQRRERREQHERALQE--EEEQLLRQRRWREEPREQQQLRRELEEI 266
Query: 1138 KAKEEQLSKKRRREE--RREKYRTQDKSSKKMRRSE 1171
+ +E++L ++ RRE+ RRE+ Q++ ++ R E
Sbjct: 267 REREQRLEQEERREQQLRREQRLEQEERREQQLRRE 302
Score = 33.1 bits (74), Expect = 4.5
Identities = 29/123 (23%), Positives = 62/123 (49%), Gaps = 6/123 (4%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQH 1111
+ + RKF + + QE+ + +E ++ + +QRR++ + R + +
Sbjct: 1046 QERDRKFR--LEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRRERDRKFREE 1103
Query: 1112 IQLINHDKMKKRKLKENEKRKAHEAEKA--KEEQLSKKRR-REERREKYRTQDKSSKKMR 1168
QL+ ++ ++R ++ RK E E+ +EEQL ++ R R+ R E+ Q+ +++R
Sbjct: 1104 EQLLQ-EREEERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLR 1162
Query: 1169 RSE 1171
R E
Sbjct: 1163 RQE 1165
Score = 32.7 bits (73), Expect = 5.9
Identities = 27/105 (25%), Positives = 52/105 (48%), Gaps = 17/105 (16%)
Query: 1082 KRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKK----RKLKENEKRKAHEAE 1137
+ + LL Q Q+ + + R+RK+ Q +Q +++++ RKL+E E+ E +
Sbjct: 891 REEEQLLRQEEQE--LRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQ 948
Query: 1138 KAK---------EEQLSKKRRRE--ERREKYRTQDKSSKKMRRSE 1171
+ + EEQL ++R E R+E+ R + + +RR E
Sbjct: 949 ELRRERARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREE 993
Score = 32.7 bits (73), Expect = 5.9
Identities = 21/101 (20%), Positives = 51/101 (49%), Gaps = 10/101 (9%)
Query: 1078 KETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHE-- 1135
++ P+R + +++ ++ E + +K QH DK ++ + +E E+R+A E
Sbjct: 129 EDEPERRRWQKQEQERELAEEEEQRKKRERFEQHYSRQYRDKEQRLQRQELEERRAEEEQ 188
Query: 1136 --------AEKAKEEQLSKKRRREERREKYRTQDKSSKKMR 1168
AE+ EE+ ++R ++E + + R +++ ++ R
Sbjct: 189 LRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERR 229
Score = 32.7 bits (73), Expect = 5.9
Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 9/99 (9%)
Query: 1079 ETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEK 1138
E + + LEQ ++ +E ER+ L + ++ I + ++++L++ E+R+ AE+
Sbjct: 304 EEIREREQRLEQEERREQRLEQEERREQQLKRELEEI---REREQRLEQEERREQLLAEE 360
Query: 1139 AKE------EQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
+E E L+++ +R+ E Q K + RR E
Sbjct: 361 VREQARERGESLTRRWQRQLESEAGARQSKVYSRPRRQE 399
>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC
6.3.2.-)
Length = 4065
Score = 47.8 bits (112), Expect = 2e-04
Identities = 58/273 (21%), Positives = 111/273 (40%), Gaps = 45/273 (16%)
Query: 462 TGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFG-------------NDADQ 508
+G+ DQAED+ D S+ + L + E R + G ++ D
Sbjct: 2356 SGTAGTDQAEDEFLSDGSSVSEDLTDDRE-ETPDLYRNSTLGMLEPGRDDEFSDEDEDDD 2414
Query: 509 SDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQL 568
D+ D +D D S D+E +EEDD+ + E P ++++
Sbjct: 2415 EDMYDDEQYDDELDYGDDMSQDNEDNPSDEEDDL--------GEMGEMGGMPGQPGVVEV 2466
Query: 569 VYGES-----TVNLISINKENDSSEDEE---SDGDFFEPIEEVKKKNVRDGLN----DGN 616
+ GE+ ++ ++++++ ED+E SD D E + ++ D ++ +GN
Sbjct: 2467 LMGENDDEEDNDDMDDMDEDDEMDEDDEQELSDEDEDEEVGSEDMDDLEDDIHIVDEEGN 2526
Query: 617 VNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRN-----GLPKATTEEENDDV 671
+D + D+ D++D EE+ N+ +A L N + +A E DD+
Sbjct: 2527 AIDDDGASWDDGTDE--DEEDEEELDYEAEAQNMQEAQLHNRRTFPEIMRAAMENAGDDL 2584
Query: 672 ----YGDFEDLETGEKIENNQTDDATHNGDDLE 700
DF+ + + + DD DD++
Sbjct: 2585 DAEPIRDFDGHYIDDDEDGEEDDDEDEGEDDMD 2617
Score = 43.1 bits (100), Expect = 0.004
Identities = 44/178 (24%), Positives = 73/178 (40%), Gaps = 43/178 (24%)
Query: 432 QDGIIETV---NYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEH 488
Q G++E + N +E D+D + + DE D L D+ ED+ G S + D LE+
Sbjct: 2460 QPGVVEVLMGENDDEEDNDDMDDMDEDDEMDEDDEQELSDEDEDEEVG--SEDMDDLEDD 2517
Query: 489 IEFHNGRRRRRAIFGNDADQSDLMDSSGN---EDGSASDDGASSDSESLNEEEEDDVMGN 545
I ++D GN +DG++ DDG D E +EEE D
Sbjct: 2518 IH--------------------IVDEEGNAIDDDGASWDDGTDEDEE---DEEELDYEAE 2554
Query: 546 VSKWKESLAERTLSQKTPSLMQLVYGESTVNLIS----------INKENDSSEDEESD 593
+E A+ + P +M+ + +L + I+ + D ED++ D
Sbjct: 2555 AQNMQE--AQLHNRRTFPEIMRAAMENAGDDLDAEPIRDFDGHYIDDDEDGEEDDDED 2610
Score = 39.3 bits (90), Expect = 0.063
Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 39/220 (17%)
Query: 361 NDHFVQFTKVDDENS-DITRKGNERDIGEVLVRSLQETKYPINEKL-ENSMINLFAQSSE 418
+D F + DDE+ D + +E D G+ + + ++ + L E +
Sbjct: 2403 DDEFSDEDEDDDEDMYDDEQYDDELDYGDDMSQDNEDNPSDEEDDLGEMGEMGGMPGQPG 2462
Query: 419 ALAEAQGANMDVEQDGIIETVNYN-EMDSDGGSESSDQDEADAMTGSGLPDQAEDD---- 473
+ G N D E + ++ ++ + EMD D E SD+DE D GS D EDD
Sbjct: 2463 VVEVLMGENDDEEDNDDMDDMDEDDEMDEDDEQELSDEDE-DEEVGSEDMDDLEDDIHIV 2521
Query: 474 -----------AAGDKSTNKDHLEEH-------------IEFHNGR------RRRRAIFG 503
A+ D T++D +E + HN R R G
Sbjct: 2522 DEEGNAIDDDGASWDDGTDEDEEDEEELDYEAEAQNMQEAQLHNRRTFPEIMRAAMENAG 2581
Query: 504 NDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVM 543
+D D + D G+ +DG D E E++ DD M
Sbjct: 2582 DDLDAEPIRDFDGHYIDD-DEDGEEDDDEDEGEDDMDDDM 2620
Score = 37.0 bits (84), Expect = 0.31
Identities = 59/264 (22%), Positives = 108/264 (40%), Gaps = 64/264 (24%)
Query: 508 QSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQ 567
Q L+ +SG ++D SD S++E+ DD ++TP L
Sbjct: 2349 QLGLIPASGTAGTDQAEDEFLSDGSSVSEDLTDD-----------------REETPDL-- 2389
Query: 568 LVYGESTVNLISINKEND-SSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKCA 626
Y ST+ ++ ++++ S EDE+ D D ++ + D L+ G+ ++D
Sbjct: 2390 --YRNSTLGMLEPGRDDEFSDEDEDDDEDMYD------DEQYDDELDYGDDMSQDNE--- 2438
Query: 627 QFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLP--------KATTEEENDDVYGDFEDL 678
D D++D+ G + + G P + EE+NDD+ ED
Sbjct: 2439 ---DNPSDEEDD--------LGEMGEMGGMPGQPGVVEVLMGENDDEEDNDDMDDMDEDD 2487
Query: 679 ETGEKIENNQTDD------ATHNGDDLEAETRRLKKLALQEDGG--NENEAKFRRGQPNE 730
E E E +D+ + + DDLE + + E+G +++ A + G +
Sbjct: 2488 EMDEDDEQELSDEDEDEEVGSEDMDDLEDDIH-----IVDEEGNAIDDDGASWDDGTDED 2542
Query: 731 TSYFDKLKEEIELQKQMNIAELND 754
++L E E Q M A+L++
Sbjct: 2543 EEDEEELDYEAEAQ-NMQEAQLHN 2565
Score = 33.5 bits (75), Expect = 3.5
Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 4/48 (8%)
Query: 1126 KENEKRKAHEAEKAKEEQLSKKRRREER--REKYRTQDKSSKKMRRSE 1171
KE + RKA KA+EE+ KKR+ EER RE ++K++++ + +E
Sbjct: 2845 KEEKARKAEADRKAEEER--KKRQEEERKKREAKEAEEKAAREKKEAE 2890
Score = 33.1 bits (74), Expect = 4.5
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 1115 INHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
I +K +K + E + RKA E K ++E+ KKR +E EK + K +++ R E
Sbjct: 2841 IQAEKEEKARKAEAD-RKAEEERKKRQEEERKKREAKEAEEKAAREKKEAEERERLE 2896
Score = 32.3 bits (72), Expect = 7.7
Identities = 14/44 (31%), Positives = 29/44 (65%)
Query: 1121 KKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSS 1164
++RK ++ E+RK EA++A+E+ +K+ EER R + +++
Sbjct: 2860 EERKKRQEEERKKREAKEAEEKAAREKKEAEERERLERERAEAA 2903
>GAR2_SCHPO (P41891) Protein gar2
Length = 500
Score = 47.4 bits (111), Expect = 2e-04
Identities = 43/206 (20%), Positives = 91/206 (43%), Gaps = 10/206 (4%)
Query: 443 EMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIF 502
E S+ SESS E+++ + +E +++ +S++ + EE + ++ +
Sbjct: 82 ESSSESESESSSS-ESESSSSESESSSSESESSSSESSSSES-EEEVIVKTEEKKESSSE 139
Query: 503 GNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKT 562
+ + +S+ + + + + + S SES + E E + + S+ +E + E+T +K
Sbjct: 140 SSSSSESEEEEEAVVKIEEKKESSSDSSSESSSSESESESSSSESEEEEEVVEKTEEKKE 199
Query: 563 PSLMQLVYGESTVNLISINKENDSSEDEESDGDF-------FEPIEEVKKKNVRDGLNDG 615
S ES+ + S + ++DSS D ES+ EP E + + D
Sbjct: 200 GSSESSSDSESSSDSSSESGDSDSSSDSESESSSEDEKKRKAEPASEERPAKITKPSQDS 259
Query: 616 NVN-TEDYSKCAQFMDKRWDKKDNEE 640
N T + + +D +W ++ EE
Sbjct: 260 NETCTVFVGRLSWNVDDQWLGQEFEE 285
Score = 42.7 bits (99), Expect = 0.006
Identities = 31/154 (20%), Positives = 70/154 (45%), Gaps = 8/154 (5%)
Query: 393 SLQETKYPINEKLENSMINLFAQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSES 452
S E++ +E +S + + S + ++ ++ + E++ I++T E S+ S S
Sbjct: 85 SESESESSSSESESSSSESESSSSESESSSSESSSSESEEEVIVKTEEKKESSSESSSSS 144
Query: 453 SDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLE-------EHIEFHNGRRRRRAIFGND 505
++E +A+ ++ D++ + S+++ E E E ++
Sbjct: 145 ESEEEEEAVVKIEEKKESSSDSSSESSSSESESESSSSESEEEEEVVEKTEEKKEGSSES 204
Query: 506 ADQSDLMDSSGNEDGSASDDGASSDSESLNEEEE 539
+ S+ S +E G SD + S+SES +E+E+
Sbjct: 205 SSDSESSSDSSSESGD-SDSSSDSESESSSEDEK 237
>DMP1_MOUSE (O55188) Dentin matrix acidic phosphoprotein 1 precursor
(Dentin matrix protein-1) (DMP-1) (AG1)
Length = 503
Score = 47.4 bits (111), Expect = 2e-04
Identities = 55/317 (17%), Positives = 115/317 (35%), Gaps = 37/317 (11%)
Query: 436 IETVNYNEMDSDGGSESSDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLE-----EHIE 490
+ Y+ +S+ E +D + E A+ + N DH E +
Sbjct: 17 LPVARYHNTESESSEERTDDLAGSPPPPTNSESSEESQASPEAQANSDHTHSSESGEELG 76
Query: 491 FHNGRRRRRAIF----GNDADQSDLMDSSGNEDGSASDDGASSDSESLNE----EEEDDV 542
+ G+ R G AD+ D D SG++ D+G + + ++D
Sbjct: 77 YDRGQYRPAGGLSKSTGTGADKDDDEDDSGDDTFGDEDNGLGPEEGQWGGPSKLDSDEDS 136
Query: 543 MGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEE 602
++S ++ +Q TP S +K+ DS +D S D + +
Sbjct: 137 ADTTQSSEDSTSQENSAQDTP---------------SDSKDQDSEDDAHSRPDAGDSAQH 181
Query: 603 VKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVTGNLAKAALRNGLPKA 662
+ + R G G+ + ++F D+ D E R+ ++ A +R+ K
Sbjct: 182 SESEEQRVG--GGSEGQSSHGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKG 239
Query: 663 TTEEENDDVYGDFEDLE--TGEKIENNQTDDATHNGDDLEAETRRLKK-----LALQEDG 715
E + D + +E + + ++ + + G+ ++ +R + A +E+
Sbjct: 240 DREPTSTQDSDDSQSVEFSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTEDTASKEES 299
Query: 716 GNENEAKFRRGQPNETS 732
+E++ Q E S
Sbjct: 300 RSESQEDTAESQSQEDS 316
Score = 46.2 bits (108), Expect = 5e-04
Identities = 68/364 (18%), Positives = 146/364 (39%), Gaps = 43/364 (11%)
Query: 371 DDENSDITRKGNERDIGEVLVRSLQETKYPINEKLENSMINLFAQ----SSEALAEAQGA 426
D++++D T+ + E S Q+T P + K ++S + ++ S +E++
Sbjct: 133 DEDSADTTQSSEDSTSQE---NSAQDT--PSDSKDQDSEDDAHSRPDAGDSAQHSESEEQ 187
Query: 427 NMDVEQDGIIETVNYNEMDSDG----GSESSDQDEADA-MTGSGLPDQAEDDAAGDKSTN 481
+ +G + +E D +G ES+ D A M+ +G+ + ST
Sbjct: 188 RVGGGSEGQSSHGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKGDREPTSTQ 247
Query: 482 KDHLEEHIEFHNGRRRRRAIFGNDADQSDLMDSSGNEDGSASDDGASSDSESLNEEEED- 540
+ +EF + + RR+ + + +L DS+ E S S + +S ES +E +ED
Sbjct: 248 DSDDSQSVEFSSRKSFRRSRVSEEDYRGELTDSNSRETQSDSTEDTASKEESRSESQEDT 307
Query: 541 -------------DVMGNVSKWKESLAERTLSQKTPSLMQLVYGESTVNLISINKENDSS 587
D S+ ++ + S+ + G++ N + DS
Sbjct: 308 AESQSQEDSPEGQDPSSESSEEAGEPSQESSSESQEGVTSESRGDNPDNTSQTGDQEDSE 367
Query: 588 EDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKCAQFMDKRWDKKDNEEIRNRFVT 647
EE + F E + D ++ +++ + S Q + D E ++++
Sbjct: 368 SSEEDSLNTFSSSESQSTEEQADSESNESLSLSEES---QESAQDGDSSSQEGLQSQ--- 421
Query: 648 GNLAKAALRNGLPKATTEEENDDVYGDFEDLETGEKIENNQTDDATHNGDD-----LEAE 702
A+ + ++ +E+++ + K E+N T A+ + +D +EA+
Sbjct: 422 ----SASTESRSQESQSEQDSRSEEDSDSQDSSRSKEESNSTGSASSSEEDIRPKNMEAD 477
Query: 703 TRRL 706
+R+L
Sbjct: 478 SRKL 481
Score = 43.5 bits (101), Expect = 0.003
Identities = 64/338 (18%), Positives = 129/338 (37%), Gaps = 28/338 (8%)
Query: 453 SDQDEADAMTGSGLPDQAEDDAAGDKSTNKDHLEEHIEFHNGRRRRRAIFGNDADQSDLM 512
SD+D AD S E+ A S +KD E + H+ R G+ A S+
Sbjct: 132 SDEDSADTTQSSEDSTSQENSAQDTPSDSKDQDSED-DAHS-----RPDAGDSAQHSESE 185
Query: 513 D---SSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLA----ERTLSQKTPSL 565
+ G+E S+ DG+ D E + ++ + + + S A E + + P+
Sbjct: 186 EQRVGGGSEGQSSHGDGSEFDDEGMQSDDPESTRSDRGHARMSSAGIRSEESKGDREPTS 245
Query: 566 MQLVYGESTVNLISINKENDSSEDEESDGDFFEPIEEVKKKNVRDGLNDGNVNTEDYSKC 625
Q +V S S EE E + ++ D D E S+
Sbjct: 246 TQDSDDSQSVEFSSRKSFRRSRVSEEDYRG--ELTDSNSRETQSDSTEDTASKEESRSES 303
Query: 626 AQFMDKRWDKKDNEE-----IRNRFVTGNLAKAALRNGLPKATTEE-----ENDDVYGDF 675
+ + ++D+ E + G ++ + T+E +N GD
Sbjct: 304 QEDTAESQSQEDSPEGQDPSSESSEEAGEPSQESSSESQEGVTSESRGDNPDNTSQTGDQ 363
Query: 676 EDLETGEKIENNQTDDATHNGDDLEAETRRLKKLALQE---DGGNENEAKFRRGQPNETS 732
ED E+ E+ N + + +A++ + L+L E + + ++ + G ++++
Sbjct: 364 EDSESSEEDSLNTFSSSESQSTEEQADSESNESLSLSEESQESAQDGDSSSQEGLQSQSA 423
Query: 733 YFDKLKEEIELQKQMNIAELNDLDEATRLEIEGFRTGT 770
+ +E + ++ E +D +++R + E TG+
Sbjct: 424 STESRSQESQSEQDSRSEEDSDSQDSSRSKEESNSTGS 461
>A3B1_HUMAN (O00203) Adapter-related protein complex 3 beta 1
subunit (Beta3A-adaptin) (Adaptor protein complex AP-3
beta-1 subunit) (AP-3 complex beta-1 subunit) (Clathrin
assembly protein complex 3 beta-1 large chain)
Length = 1094
Score = 47.0 bits (110), Expect = 3e-04
Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 32/176 (18%)
Query: 404 KLENSMINLFAQSSEALAEAQGANMDVEQDGIIETVNYNEMDSDGGSESSDQDEADAMTG 463
K ENS +++S E E+D + + ++ +S+ GSES +Q E
Sbjct: 667 KQENSAKKFYSESEE------------EEDS---SDSSSDSESESGSESGEQGE------ 705
Query: 464 SGLPDQAEDDAAGDKSTNKDH---LEEHIEFHNGRRRRRAIFGN--------DADQSDLM 512
SG + +D++ D S+ +D E +E +R G + ++S
Sbjct: 706 SGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTS 765
Query: 513 DSSGNEDGSASDDGASSDSESLNEEEEDDVMGNVSKWKESLAERTLSQKTPSLMQL 568
DSS +E S D + S+SES E E + K K++ +RT K SL+ L
Sbjct: 766 DSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDL 821
>TRHY_HUMAN (Q07283) Trichohyalin
Length = 1898
Score = 46.6 bits (109), Expect = 4e-04
Identities = 40/167 (23%), Positives = 78/167 (45%), Gaps = 16/167 (9%)
Query: 1017 QPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASK 1076
Q RDQ W+ RR H L K +L +++ ++ + +ER +
Sbjct: 885 QRRDQKWRWQLEEERKRRRHTLYA---KPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 941
Query: 1077 PKETPKRNQPLLEQRRQKGVVMEPRE-----------RKVLALVQHIQLINHDKMKKRKL 1125
+E R + L+Q ++ ++ E RE RK L Q + + ++ +KR+
Sbjct: 942 EQERQYREEEQLQQEEEQ-LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 1000
Query: 1126 KENEKRKAHEAE-KAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
+E EK+ E E + +EEQL ++ R + RR+++ Q + ++++ E
Sbjct: 1001 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1047
Score = 43.5 bits (101), Expect = 0.003
Identities = 31/146 (21%), Positives = 75/146 (51%), Gaps = 4/146 (2%)
Query: 1026 MRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQ 1085
+R +LRR+ L ++ +K E++ R+ + R +ER + + +ET + Q
Sbjct: 432 LRREQQLRREQQLRREQEEERHEQKHEQERREQR---LKREQEERRDWLKREEETERHEQ 488
Query: 1086 PLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLS 1145
+Q+ ++ E RER L L + + ++ +++ +E E+R+ ++ +EE+
Sbjct: 489 ERRKQQLKRDQEEERRERW-LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 547
Query: 1146 KKRRREERREKYRTQDKSSKKMRRSE 1171
++R R E++ + +++ + ++R E
Sbjct: 548 QQRLRSEQQLRREQEERLEQLLKREE 573
Score = 43.5 bits (101), Expect = 0.003
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 1026 MRTVAELRRDHDLPVPVNKDSLYKKIERKPRKF-NPLVVPRSLQERLPFASKPKETPKRN 1084
+R E RR + KD KK+++K + R QER + +E +
Sbjct: 961 LREEREKRRRQERERQYRKD---KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1017
Query: 1085 QPLLEQRRQKG--VVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAE-KAKE 1141
+ LL + R+K E + RK L Q + + ++ +KR+L+E E++ E E + +E
Sbjct: 1018 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1077
Query: 1142 EQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
EQL + R RR++ Q + +++++ E
Sbjct: 1078 EQLLGEERETRRRQELERQYRKEEELQQEE 1107
Score = 43.5 bits (101), Expect = 0.003
Identities = 37/133 (27%), Positives = 70/133 (51%), Gaps = 10/133 (7%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQ--KGVVMEPR 1101
KD L ++ E+ R+ R LQER + +E + + LL + R+ + +E +
Sbjct: 1040 KDELQQEEEQLLREERE---KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1096
Query: 1102 ERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAE-KAKEEQLSK----KRRREERREK 1156
RK L Q + + ++ +KR+ +E E++ E E + +EEQL + KRRR+E +
Sbjct: 1097 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1156
Query: 1157 YRTQDKSSKKMRR 1169
YR +++ ++ R+
Sbjct: 1157 YREEEELQRQKRK 1169
Score = 43.1 bits (100), Expect = 0.004
Identities = 30/126 (23%), Positives = 57/126 (44%), Gaps = 4/126 (3%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRER 1103
+D L K+ E + ++ + R +ERL K +E + Q R K E R
Sbjct: 594 RDQLLKREEERRQQR----LKREQEERLEQRLKREEVERLEQEERRDERLKREEPEEERR 649
Query: 1104 KVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKS 1163
L + + H+++++ + + E+R E E+ + EQ K+ EERRE+ +++
Sbjct: 650 HELLKSEEQEERRHEQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 709
Query: 1164 SKKMRR 1169
+ R
Sbjct: 710 EQARER 715
Score = 40.8 bits (94), Expect = 0.022
Identities = 31/148 (20%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 1027 RTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQP 1086
R +L+RD + + + K+E + R R QER + ++ +R Q
Sbjct: 490 RRKQQLKRDQE----EERRERWLKLEEEER--------REQQERREQQLRREQEERREQR 537
Query: 1087 LLEQRRQKGVVMEPRERKVLALVQHI---QLINHDKMKKRKLKENEKRKAHEAEKAKEEQ 1143
L Q ++ + R + L Q QL+ ++ K+ + + E+R E E+ +++
Sbjct: 538 LKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQL 597
Query: 1144 LSKKRRREERREKYRTQDKSSKKMRRSE 1171
L ++ R ++R K +++ ++++R E
Sbjct: 598 LKREEERRQQRLKREQEERLEQRLKREE 625
Score = 40.0 bits (92), Expect = 0.037
Identities = 22/88 (25%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Query: 1082 KRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKE 1141
+ ++ LL++R ++ + + R+RK L + QL ++ +++L+ + RK E E+ +
Sbjct: 1577 REDEQLLQEREEQQLHRQERDRKFLE--EEPQLRRQER--EQQLRHDRDRKFREEEQLLQ 1632
Query: 1142 EQLSKKRRREERREKYRTQDKSSKKMRR 1169
E ++ RR+ER K+R +++ ++ R
Sbjct: 1633 EGEEQQLRRQERDRKFREEEQQLRRQER 1660
Score = 39.3 bits (90), Expect = 0.063
Identities = 35/129 (27%), Positives = 62/129 (47%), Gaps = 11/129 (8%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFAS-KPKETPKRNQPLLEQRR-------QKGVVMEPRER 1103
E + RKF L+ER + ++ + Q L Q R ++ V + RER
Sbjct: 1343 EERERKFLKEEQQLRLEEREQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1402
Query: 1104 KVLALVQHIQLINHDKMKKRK--LKENEKRKAHEAEK-AKEEQLSKKRRREERREKYRTQ 1160
K L Q ++ H K ++ + L+E E+++ H E+ K + ++ RR+ER K+R Q
Sbjct: 1403 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1462
Query: 1161 DKSSKKMRR 1169
+ S++ R
Sbjct: 1463 ELRSQEPER 1471
Score = 38.1 bits (87), Expect = 0.14
Identities = 28/121 (23%), Positives = 57/121 (46%), Gaps = 10/121 (8%)
Query: 1049 KKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLAL 1108
+K ER ++ + R +ER A + ++ +R P E++ Q+G RE+++ L
Sbjct: 793 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRGRQRREREKELQFL 852
Query: 1109 VQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMR 1168
+ QL ++ ++ E E +E ++R+ + R +K+R Q + +K R
Sbjct: 853 EEEEQLQRRER----------AQQLQEEEDGLQEDQERRRQEQRRDQKWRWQLEEERKRR 902
Query: 1169 R 1169
R
Sbjct: 903 R 903
Score = 37.7 bits (86), Expect = 0.18
Identities = 36/160 (22%), Positives = 69/160 (42%), Gaps = 8/160 (5%)
Query: 1020 DQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKE 1079
+Q + R E D + ++ ++++R+ + + R ERL + E
Sbjct: 578 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRDE 637
Query: 1080 TPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKK--------RKLKENEKR 1131
KR +P E+R + E ER+ L + Q ++K+ ++LK +
Sbjct: 638 RLKREEPEEERRHELLKSEEQEERRHEQLRREQQERREQRLKREEEEERLEQRLKREHEE 697
Query: 1132 KAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
+ E E A+EEQ + R + R K++ Q +S R+S+
Sbjct: 698 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 737
Score = 36.2 bits (82), Expect = 0.54
Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 13/128 (10%)
Query: 1049 KKIERKPRKFNPLVVPRSLQERLPFASKPKETPKR---NQPLLEQRRQKGVVMEPRERKV 1105
K+ +R+ RK + L+E + +ET ++ + LL++R ++ ++ + R+RK
Sbjct: 1263 KEAKRRDRKSQE--EKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLLRQERDRKF 1320
Query: 1106 LALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERRE----KYRTQD 1161
+ +L++ ++ +K +E R+ E + KEEQ + RE+ R+ K+R ++
Sbjct: 1321 ----REEELLHQEQGRKFLEEEQRLREERERKFLKEEQQLRLEEREQLRQDRDRKFREEE 1376
Query: 1162 KSSKKMRR 1169
+ + R
Sbjct: 1377 QQLSRQER 1384
Score = 35.0 bits (79), Expect = 1.2
Identities = 29/137 (21%), Positives = 69/137 (50%), Gaps = 11/137 (8%)
Query: 1044 KDSLYKKIERKPRKFNPLVVPRS---LQERLPFASKPKETPKRNQPLLEQRRQKGVVMEP 1100
+D ++++ E K + V+ + LQE P + +E + + L + RQ+
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP--QRQRELQEEEEQLRKLERQELRRERQ 291
Query: 1101 RERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRR--EERRE--- 1155
E + ++ Q + + ++R+ ++ E+R+ E + +EE+ ++ RR EERRE
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 1156 -KYRTQDKSSKKMRRSE 1171
+ + +++ +++RR +
Sbjct: 352 RREQEEERREQQLRREQ 368
Score = 35.0 bits (79), Expect = 1.2
Identities = 32/121 (26%), Positives = 62/121 (50%), Gaps = 10/121 (8%)
Query: 1052 ERKPRKFNPLVVPRSLQER-LPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQ 1110
+ + RKF QER F + + + + LE+ +Q + + R+RK L Q
Sbjct: 1437 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ--LHRQQRQRKFLQEEQ 1494
Query: 1111 HIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRS 1170
QL ++ ++R+ ++ RK E E+ ++E+ ++ R+ER K+R ++ +K+RR
Sbjct: 1495 --QLRRQERGQQRR--QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE---QKVRRQ 1547
Query: 1171 E 1171
E
Sbjct: 1548 E 1548
Score = 34.7 bits (78), Expect = 1.6
Identities = 25/94 (26%), Positives = 47/94 (49%), Gaps = 8/94 (8%)
Query: 1068 QERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKE 1127
QER + + P+ Q LE+ QK R+ + + QL+ ++ +KR+ +E
Sbjct: 1239 QERRRWQQANRHFPEEEQ--LEREEQKEAKRRDRKSQ-----EEKQLLREEREEKRRRQE 1291
Query: 1128 NEKRKAHEAEKAKEEQLSKKRRREERREKYRTQD 1161
+ RK E E+ +E+ + R+ER K+R ++
Sbjct: 1292 TD-RKFREEEQLLQEREEQPLLRQERDRKFREEE 1324
Score = 34.3 bits (77), Expect = 2.0
Identities = 30/152 (19%), Positives = 73/152 (47%), Gaps = 11/152 (7%)
Query: 1027 RTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQP 1086
R +LRR+ + ++ ++ + + R+ L + + R + +E +R Q
Sbjct: 334 RREQQLRREQE----ERREQQLRREQEEERREQQLRREQEEERREQQLRREQEEERREQQ 389
Query: 1087 LLEQ---RRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKL--KENEKRKAHEAEKAKE 1141
L + RR++ + E + R+ L + QL ++++ + +E + R+ + + +E
Sbjct: 390 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 449
Query: 1142 EQLSKKRRREERREK--YRTQDKSSKKMRRSE 1171
E+ +++ +ERRE+ R Q++ ++R E
Sbjct: 450 EERHEQKHEQERREQRLKREQEERRDWLKREE 481
Score = 33.9 bits (76), Expect = 2.7
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 9/95 (9%)
Query: 1076 KPKETPKRNQPLLEQRRQKGVVMEP----RERKVLALVQHIQLINHDKMKKRKLKENEKR 1131
K E + + LL + R+K + E RE + L + L + ++R+ E + R
Sbjct: 1039 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1098
Query: 1132 KAHEAEKAKEEQL----SKKRRREERREKYRTQDK 1162
K E ++ +EEQL +KRRR+ER + R +++
Sbjct: 1099 KEEELQQ-EEEQLLREEPEKRRRQERERQCREEEE 1132
Score = 33.5 bits (75), Expect = 3.5
Identities = 23/104 (22%), Positives = 51/104 (48%), Gaps = 15/104 (14%)
Query: 1068 QERLPFASKPKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKE 1127
+ER + +E +R + E+RR++ + E ER+ + + R+ +E
Sbjct: 312 EERREQQEERREQQERREQQ-EERREQQLRREQEERR--------------EQQLRREQE 356
Query: 1128 NEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
E+R+ + +EE+ ++ RRE+ E+ Q + +++RR +
Sbjct: 357 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 400
Score = 33.1 bits (74), Expect = 4.5
Identities = 31/160 (19%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 1017 QPRDQTWKGMRTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASK 1076
+ ++ W+ TV + + ++ E + RK + R QE +
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 1077 -PKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHE 1135
+E R + E+R Q+ E +ER+ + Q + ++ ++R E++ E
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR-----EQQLRRE 354
Query: 1136 AEKAKEEQLSKKRRREERRE----KYRTQDKSSKKMRRSE 1171
E+ + EQ ++ + EERRE + + +++ +++RR +
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 394
Score = 32.7 bits (73), Expect = 5.9
Identities = 35/167 (20%), Positives = 74/167 (43%), Gaps = 24/167 (14%)
Query: 1027 RTVAELRRDHDLPVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQP 1086
R E RR+ L ++ +++ R+ + + R Q R + ++ +R Q
Sbjct: 366 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 425
Query: 1087 LLEQ---RRQKGVVMEPRERKVLALVQHIQLINHDKMKKRK----------LKENEKRKA 1133
L + RR++ + E + R+ +H Q ++ ++R LK E+ +
Sbjct: 426 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 485
Query: 1134 HEAEKAKEEQLSKKRRREERREKY---------RTQDKSSKKMRRSE 1171
HE E+ K++ K+ + EERRE++ Q++ +++RR +
Sbjct: 486 HEQERRKQQ--LKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 530
Score = 32.7 bits (73), Expect = 5.9
Identities = 30/130 (23%), Positives = 67/130 (51%), Gaps = 15/130 (11%)
Query: 1052 ERKPRKFNPLVVPRSLQERLPFASK-PKETPKRNQPLLEQRRQKGVVMEPRERKVLALVQ 1110
ER+ ++ LQ+RL + +E +R + LL++ +K + E RE+++ +
Sbjct: 532 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQE 591
Query: 1111 HIQ---LINHDKMKKRKLK-ENEKR-----KAHEAEKAKEEQLSKKRRREERREKYRTQD 1161
+ L ++ ++++LK E E+R K E E+ ++E+ RR+ER ++ ++
Sbjct: 592 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE-----RRDERLKREEPEE 646
Query: 1162 KSSKKMRRSE 1171
+ ++ +SE
Sbjct: 647 ERRHELLKSE 656
Score = 32.3 bits (72), Expect = 7.7
Identities = 19/108 (17%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Query: 1065 RSLQERLPFASKPKETPKRNQPLLEQRRQKGVVMEP-RERKVLALVQHIQLINHDKMKKR 1123
R Q+R+ + KE KR + +L + +K EP R+R++ + ++ + ++++
Sbjct: 231 RERQDRVFQEEEEKEWRKR-ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 1124 KLKENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRRSE 1171
+ +E ++++ E+ + ++RR ++ + + + + ++ RR +
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Score = 32.3 bits (72), Expect = 7.7
Identities = 40/172 (23%), Positives = 74/172 (42%), Gaps = 31/172 (18%)
Query: 1027 RTVAELRRDHDL----PVPVNKDSLYKKIERKPRKFNPLVVPRSLQERLPFASKPKETPK 1082
R E RRD L P + L K E++ R+ L R QER K +E +
Sbjct: 628 RLEQEERRDERLKREEPEEERRHELLKSEEQEERRHEQL--RREQQERREQRLKREEEEE 685
Query: 1083 RNQPLL-----EQRRQKGVVMEPRERKVLALVQHI-----QLINHDKMKKRKL------- 1125
R + L E+RR++ + E +E+ + I QL + ++ K+
Sbjct: 686 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVLLEAPQA 745
Query: 1126 --------KENEKRKAHEAEKAKEEQLSKKRRREERREKYRTQDKSSKKMRR 1169
+E ++R+ E + +EE+ ++++ EE+R + Q ++ +K R
Sbjct: 746 GRAEAPQEQEEKRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 797
Score = 32.3 bits (72), Expect = 7.7
Identities = 29/132 (21%), Positives = 63/132 (46%), Gaps = 9/132 (6%)
Query: 1044 KDSLY--KKIERKPRKFNPLVVPRSLQERLPFASKPKETPKRNQPLLE----QRRQKGVV 1097
K+SL ++ E R+F P R L+E P + ++ ++ + L E +Q+ +
Sbjct: 106 KESLLQDRRTEEDQRRFEPR--DRQLEEE-PGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 1098 MEPRERKVLALVQHIQLINHDKMKKRKLKENEKRKAHEAEKAKEEQLSKKRRREERREKY 1157
R+R+ L + Q + ++ + ++ + K HE E+ +E+ ++R E R K
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 1158 RTQDKSSKKMRR 1169
R + + ++ R+
Sbjct: 223 REEKQQQRRERQ 234
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.314 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 143,203,620
Number of Sequences: 164201
Number of extensions: 6689928
Number of successful extensions: 30380
Number of sequences better than 10.0: 580
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 468
Number of HSP's that attempted gapping in prelim test: 24818
Number of HSP's gapped (non-prelim): 3226
length of query: 1172
length of database: 59,974,054
effective HSP length: 121
effective length of query: 1051
effective length of database: 40,105,733
effective search space: 42151125383
effective search space used: 42151125383
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 72 (32.3 bits)
Lotus: description of TM0122.3