BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0106.7
(717 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GYP7_YARLI (P09379) GTPase-activating protein GYP7 (GAP for YPT7) 109 3e-23
GYP7_CANGA (Q6FWI1) GTPase-activating protein GYP7 (GAP for YPT7) 105 5e-22
GYP7_DEBHA (Q6BU76) GTPase-activating protein GYP7 (GAP for YPT7) 94 1e-18
GYP7_YEAST (P48365) GTPase-activating protein GYP7 (GAP for YPT7) 87 2e-16
GYP1_YEAST (Q08484) GTPase-activating protein GYP1 (GAP for YPT1) 81 8e-15
CV4L_MACFA (Q95LL3) TBC1 domain family protein C6orf197 homolog ... 74 1e-12
CV4L_HUMAN (Q9NU19) TBC1 domain family protein C6orf197 74 1e-12
CV04_MOUSE (Q8R5A6) TBC1 domain family protein C22orf4 homolog (... 62 5e-09
CV04_MACFA (Q95KI1) TBC1 domain family protein C22orf4 homolog (... 62 7e-09
CV04_HUMAN (Q8WUA7) TBC1 domain family protein C22orf4 62 7e-09
TB13_MOUSE (Q8R3D1) TBC1 domain family member 13 59 3e-08
TBC2_HUMAN (Q9BYX2) TBC1 domain family member 2 (Prostate antige... 55 8e-07
CC16_SCHPO (P36618) Cell division control protein 16 50 3e-05
GYP2_YEAST (P53258) GTPase-activating protein GYP2 (MAC1-depende... 48 1e-04
TB10_HUMAN (Q9BXI6) TBC1 domain family member 10 (EBP50-PDX inte... 44 0.001
TB10_MOUSE (P58802) TBC1 domain family member 10 (EBP50-PDX inte... 44 0.001
TBC8_HUMAN (O95759) TBC1 domain family member 8 (Vascular Rab-GA... 42 0.007
US6L_MOUSE (Q80XC3) USP6 N-terminal like protein 41 0.010
US6L_HUMAN (Q92738) USP6 N-terminal like protein (Related to the... 41 0.010
AZF1_YEAST (P41696) Asparagine-rich zinc finger protein AZF1 41 0.010
>GYP7_YARLI (P09379) GTPase-activating protein GYP7 (GAP for YPT7)
Length = 730
Score = 109 bits (272), Expect = 3e-23
Identities = 100/385 (25%), Positives = 162/385 (41%), Gaps = 82/385 (21%)
Query: 223 NLGRETDGSHCVIDSPFDFPALPVPNLF-----EKSGKDNNSSTEHGSKLS--------- 268
NL + T + V +D PV L +K G D +S+ + +K +
Sbjct: 264 NLAKVTQLTRKVSQGVWDSSPQPVKQLLMKPEVKKIGDDFDSARIYLAKWALSVAEESQR 323
Query: 269 ARHRLRFDDEMHTFQINDNVDLIGESNGQQPRG--------ILHSTNSEIEVASPDEDE- 319
A+ ++ FDDE+ ++ +LI N Q R N + V + E
Sbjct: 324 AKLKVLFDDELRELVSDEGFELIDAENNPQRRNEVSLAEWNAFFDYNGRLIVTVNEVKER 383
Query: 320 -----------PE--------FPSDNAVYEA-QMVNQLKISDVPQPARISAAMSQEWPVG 359
PE +P D+ E ++V++L++ + +EW V
Sbjct: 384 IFHGGLAPAVRPEGWLFLLGVYPWDSTAAERKELVSKLRVD--------YNRLKKEWWVQ 435
Query: 360 EDRVSEWLWT--LHRIVVDVVRTDSHLDFYEDTR-------------------------N 392
ED+ + W L RI DV RTD ++ F+ + +
Sbjct: 436 EDKERDDFWRDQLSRIEKDVHRTDRNITFFAECDAKKDGDDDNYDKDEFGFSSQINSNIH 495
Query: 393 LARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNADAFWCFEMLLRRMRENFQMEG 452
L ++ D+L Y + GY QGMSDLLSP V+ +D+ AFW F + RM N+ +
Sbjct: 496 LIQLRDMLITYNQHNKNLGYVQGMSDLLSPLYVVLQDDTLAFWAFSAFMERMERNY-LRD 554
Query: 453 PTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWEM 512
+ + QL L H+++ ++ HL K + +L F FRMLLV F+REL +++ L +WE+
Sbjct: 555 QSGMRNQLLCLDHLVQFMLPSLYKHLEKTESTNLFFFFRMLLVWFKRELLWDDVLRLWEV 614
Query: 513 MWAADFDESLAYDLEVNCLEALDIH 537
+W + CL LD H
Sbjct: 615 LWTDYLSSQFVLFV---CLAILDKH 636
Score = 48.1 bits (113), Expect = 8e-05
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Query: 55 KWQALSDSEGK-VLGFRKALKLIVLGGVDPSIRPEVWEFLLGCYALSSTAEYRRRLRAAR 113
+W A D G+ ++ + + I GG+ P++RPE W FLLG Y STA R+ L +
Sbjct: 362 EWNAFFDYNGRLIVTVNEVKERIFHGGLAPAVRPEGWLFLLGVYPWDSTAAERKELVSKL 421
Query: 114 REHYSDLVKQ 123
R Y+ L K+
Sbjct: 422 RVDYNRLKKE 431
>GYP7_CANGA (Q6FWI1) GTPase-activating protein GYP7 (GAP for YPT7)
Length = 745
Score = 105 bits (261), Expect = 5e-22
Identities = 65/193 (33%), Positives = 93/193 (47%), Gaps = 25/193 (12%)
Query: 352 MSQEWPVGEDRVSEWLWTLHRIVVDVVRTDSHLDFY-----------EDTR--------- 391
+ +E + D W L RI DV R D ++D Y EDT
Sbjct: 436 VDREVNLDNDEEEYWKDQLFRIEKDVKRNDRNIDIYKYNTSDNLPFPEDTAPTTDDDDSI 495
Query: 392 ---NLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNADAFWCFEMLLRRMRENF 448
NL +++DIL Y +P GY QGM+DLLSP I D FWCF + RM NF
Sbjct: 496 KNPNLKKLADILTTYNIFNPNLGYVQGMTDLLSPLYYIIRDEETTFWCFTNFMERMERNF 555
Query: 449 QMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALS 508
+ + + Q+ L + +L + AHL K + L F FRMLLV F+RE ++++ +
Sbjct: 556 -LRDQSGIRDQMLALTDLCQLMLPRLSAHLQKCDSSDLFFCFRMLLVWFKREFNYDDIFN 614
Query: 509 MWEMMWAADFDES 521
+WE+ + DF S
Sbjct: 615 IWEVFF-TDFYSS 626
Score = 55.1 bits (131), Expect = 6e-07
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 14/130 (10%)
Query: 48 NRMLKPDKWQALSDSEGKVLGFRKALKLIVLGG--VDPSIRPEVWEFLLGCYALSSTAEY 105
N + KW +L DSEG++ +K + G D + R EVW FLLG Y S+ +
Sbjct: 357 NHPMTKQKWNSLFDSEGRLTVTVNEVKDYIFHGGLADDATRKEVWPFLLGVYPWDSSEDE 416
Query: 106 RRRLRAARREHYSDLVKQCQTMHSSVGTGSLAYVVGSKVMDMRTSSKLEREMKGKTSTSN 165
R++LR A + Y +L ++ ++ Y ++E+++K N
Sbjct: 417 RKQLRKALHDEYMELKQKWVDREVNLDNDEEEYWKDQLF-------RIEKDVK-----RN 464
Query: 166 DNNIEVGKYN 175
D NI++ KYN
Sbjct: 465 DRNIDIYKYN 474
>GYP7_DEBHA (Q6BU76) GTPase-activating protein GYP7 (GAP for YPT7)
Length = 757
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/201 (28%), Positives = 93/201 (45%), Gaps = 42/201 (20%)
Query: 355 EWPVGEDRVSEWLWT--LHRIVVDVVRTDSHLDFYEDTRNLA------------------ 394
+W +D+ S W HRI D+ RTD +L +++ + ++
Sbjct: 438 KWVNDDDKRSVDFWKDQKHRIEKDINRTDRNLSIFQNKKKISISGVGSDRLPTTRESSPE 497
Query: 395 ---------------------RMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNADA 433
+M +IL Y + GY QGM+DLLSP V F+D +
Sbjct: 498 TPDEADDDEFDVSNITNPHLFKMREILLTYNEHNVNLGYVQGMTDLLSPLYVTFQDESLT 557
Query: 434 FWCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRML 493
FW F + RM NF + + + Q+ L +++ ++F HL K + L+F FRML
Sbjct: 558 FWAFVNFMDRMERNF-LRDQSGMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYFFFRML 616
Query: 494 LVLFRRELSFNEALSMWEMMW 514
LV F+RE ++ LS+WE++W
Sbjct: 617 LVWFKREFEWSSVLSLWEILW 637
Score = 41.6 bits (96), Expect = 0.007
Identities = 22/67 (32%), Positives = 36/67 (52%), Gaps = 1/67 (1%)
Query: 55 KWQALSDSEGK-VLGFRKALKLIVLGGVDPSIRPEVWEFLLGCYALSSTAEYRRRLRAAR 113
+W+ L D G+ ++ + I GG++ IR E W FLL Y S+AE R+ LR +
Sbjct: 369 EWEGLFDFSGRLIISIDEIKDRIFHGGLEDCIRGEAWLFLLNVYPWDSSAEERKTLRNSF 428
Query: 114 REHYSDL 120
+ Y ++
Sbjct: 429 QTAYEEI 435
>GYP7_YEAST (P48365) GTPase-activating protein GYP7 (GAP for YPT7)
Length = 746
Score = 86.7 bits (213), Expect = 2e-16
Identities = 44/123 (35%), Positives = 68/123 (54%), Gaps = 1/123 (0%)
Query: 392 NLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNADAFWCFEMLLRRMRENFQME 451
+L + +IL Y + GY QGM+DLLSP VI ++ FWCF + M NF +
Sbjct: 509 HLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNF-LR 567
Query: 452 GPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWE 511
+ + +Q+ L +++L E+ HL+K + +L F FRMLLV F+RE + + +WE
Sbjct: 568 DQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIWE 627
Query: 512 MMW 514
W
Sbjct: 628 NFW 630
>GYP1_YEAST (Q08484) GTPase-activating protein GYP1 (GAP for YPT1)
Length = 637
Score = 81.3 bits (199), Expect = 8e-15
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 29/179 (16%)
Query: 361 DRVSEWLWTLHRIVVDVVRTDSHLDFYEDTRNLARMSDILAVYAWVDPATGYCQGMSDLL 420
D+ S + T H+I +D+ RT+ H+ Y+ + IL ++A PA+GY QG++DL+
Sbjct: 325 DQHSRDIPTWHQIEIDIPRTNPHIPLYQFKSVQNSLQRILYLWAIRHPASGYVQGINDLV 384
Query: 421 SPFVVIF----------------------------EDNADAFWCFEMLLRRMRENFQMEG 452
+PF F + AD FWC LL ++ +N+ + G
Sbjct: 385 TPFFETFLTEYLPPSQIDDVEIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNY-IHG 443
Query: 453 PTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWE 511
+++Q++ L +++ D +++ H E + FAFR + L RE + MW+
Sbjct: 444 QPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWD 502
>CV4L_MACFA (Q95LL3) TBC1 domain family protein C6orf197 homolog
(QtsA-20424)
Length = 505
Score = 74.3 bits (181), Expect = 1e-12
Identities = 46/166 (27%), Positives = 80/166 (47%), Gaps = 24/166 (14%)
Query: 369 TLHRIVVDVVRTDSHLDFYEDTRNLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIF- 427
T +I +D+ RT+ + ++ IL ++A PA+GY QG++DL++PF V+F
Sbjct: 264 TYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFL 323
Query: 428 -----ED-----------------NADAFWCFEMLLRRMRENFQMEGPTRVMKQLRELWH 465
ED AD+FWC LL +++N+ P + K+++ L
Sbjct: 324 SEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQP-GIQKKVKALEE 382
Query: 466 ILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWE 511
++ D+++ H + E L FAFR + L REL + +W+
Sbjct: 383 LVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWD 428
>CV4L_HUMAN (Q9NU19) TBC1 domain family protein C6orf197
Length = 505
Score = 74.3 bits (181), Expect = 1e-12
Identities = 46/166 (27%), Positives = 80/166 (47%), Gaps = 24/166 (14%)
Query: 369 TLHRIVVDVVRTDSHLDFYEDTRNLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIF- 427
T +I +D+ RT+ + ++ IL ++A PA+GY QG++DL++PF V+F
Sbjct: 264 TYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFL 323
Query: 428 -----ED-----------------NADAFWCFEMLLRRMRENFQMEGPTRVMKQLRELWH 465
ED AD+FWC LL +++N+ P + K+++ L
Sbjct: 324 SEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQP-GIQKKVKALEE 382
Query: 466 ILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWE 511
++ D+++ H + E L FAFR + L REL + +W+
Sbjct: 383 LVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWD 428
>CV04_MOUSE (Q8R5A6) TBC1 domain family protein C22orf4 homolog
(Fragment)
Length = 353
Score = 62.0 bits (149), Expect = 5e-09
Identities = 41/137 (29%), Positives = 64/137 (45%), Gaps = 25/137 (18%)
Query: 399 ILAVYAWVDPATGYCQGMSDLLSPFVVIF-------ED-----------------NADAF 434
IL ++A PA+GY QG++DL++PF V+F ED AD +
Sbjct: 141 ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDREDVDKVDVSSVPAEVLRNIEADTY 200
Query: 435 WCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLL 494
WC LL +++N+ P MK ++ L ++ D+ + HL L FAFR +
Sbjct: 201 WCMSKLLDGIQDNYTFAQPGIQMK-VKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMN 259
Query: 495 VLFRRELSFNEALSMWE 511
L REL + +W+
Sbjct: 260 NLLMRELPLRCTIRLWD 276
>CV04_MACFA (Q95KI1) TBC1 domain family protein C22orf4 homolog
(QtrA-11492) (Fragment)
Length = 497
Score = 61.6 bits (148), Expect = 7e-09
Identities = 38/137 (27%), Positives = 64/137 (45%), Gaps = 25/137 (18%)
Query: 399 ILAVYAWVDPATGYCQGMSDLLSPFVVIF------------------------EDNADAF 434
IL ++A PA+GY QG++DL++PF V+F AD +
Sbjct: 285 ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLRNIEADTY 344
Query: 435 WCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLL 494
WC LL +++N+ P MK ++ L ++ D+++ HL + L FAFR +
Sbjct: 345 WCMSKLLDGIQDNYTFAQPGIQMK-VKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMN 403
Query: 495 VLFRRELSFNEALSMWE 511
L RE+ + +W+
Sbjct: 404 NLLMREVPLRCTIRLWD 420
>CV04_HUMAN (Q8WUA7) TBC1 domain family protein C22orf4
Length = 517
Score = 61.6 bits (148), Expect = 7e-09
Identities = 38/137 (27%), Positives = 64/137 (45%), Gaps = 25/137 (18%)
Query: 399 ILAVYAWVDPATGYCQGMSDLLSPFVVIF------------------------EDNADAF 434
IL ++A PA+GY QG++DL++PF V+F AD +
Sbjct: 305 ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTY 364
Query: 435 WCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLL 494
WC LL +++N+ P MK ++ L ++ D+++ HL + L FAFR +
Sbjct: 365 WCMSKLLDGIQDNYTFAQPGIQMK-VKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMN 423
Query: 495 VLFRRELSFNEALSMWE 511
L RE+ + +W+
Sbjct: 424 NLLMREVPLRCTIRLWD 440
>TB13_MOUSE (Q8R3D1) TBC1 domain family member 13
Length = 400
Score = 59.3 bits (142), Expect = 3e-08
Identities = 33/130 (25%), Positives = 65/130 (49%), Gaps = 13/130 (10%)
Query: 399 ILAVYAWVDPATGYCQGMSDLLSPFVVIFEDN----------ADAFWCFEMLLRRMRENF 448
IL +YA ++P Y QGM++++ P F + AD F+CF L+ +R+NF
Sbjct: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
Query: 449 QM---EGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNE 505
+ + ++ +++ L+ D E++ L + + FAFR L +L +E +
Sbjct: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQSIKPQFFAFRWLTLLLSQEFLLPD 333
Query: 506 ALSMWEMMWA 515
+ +W+ ++A
Sbjct: 334 VIRIWDSLFA 343
>TBC2_HUMAN (Q9BYX2) TBC1 domain family member 2 (Prostate antigen
recognized and indentified by SEREX) (PARIS-1)
Length = 917
Score = 54.7 bits (130), Expect = 8e-07
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
Query: 395 RMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNADAFWCFEMLLRR-MRENFQMEGP 453
++ +L ++W +P GYCQG++ L + +++ E+ AFWC ++ M ++
Sbjct: 694 KLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTL 753
Query: 454 TRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFRMLLVLFRRELSFNEALSMWE 511
T R L +L + AHL + + F LV+F L N L +W+
Sbjct: 754 TASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWD 811
>CC16_SCHPO (P36618) Cell division control protein 16
Length = 299
Score = 49.7 bits (117), Expect = 3e-05
Identities = 38/144 (26%), Positives = 66/144 (45%), Gaps = 1/144 (0%)
Query: 372 RIVVDVVRTDSHLDFYEDTRNLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFEDNA 431
+I DV RT + + + +S +L Y W A Y QGM+ L SPF+ +
Sbjct: 79 KIQNDVSRTLVVESQFHSRVSQSSLSRLLNAYVWKRGAL-YVQGMNVLASPFLYACKSEN 137
Query: 432 DAFWCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESLHFAFR 491
AF F+ LL+ + + V + + L LE+ D ++ +L G + +A
Sbjct: 138 QAFQFFDRLLQNECPLYVLPNIDGVHRGAKLLDKCLEVLDHRLYTYLLSKGLTAKIYALP 197
Query: 492 MLLVLFRRELSFNEALSMWEMMWA 515
+L L +EAL++W+ ++A
Sbjct: 198 SILTLSACTAPLSEALTIWDFLFA 221
>GYP2_YEAST (P53258) GTPase-activating protein GYP2 (MAC1-dependent
regulator) (MIC1 protein)
Length = 950
Score = 47.8 bits (112), Expect = 1e-04
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 370 LHRIVVDVVRTDSHLDFYEDTRNLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIFED 429
+ I D+ R+ Y+ + R+ ++L Y+W +P GYCQ M+ +++ F +IF
Sbjct: 286 IDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGF-LIFMS 344
Query: 430 NADAFWC 436
AFWC
Sbjct: 345 EEQAFWC 351
>TB10_HUMAN (Q9BXI6) TBC1 domain family member 10 (EBP50-PDX
interactor of 64 kDa) (EPI64 protein)
Length = 508
Score = 44.3 bits (103), Expect = 0.001
Identities = 32/148 (21%), Positives = 60/148 (39%), Gaps = 10/148 (6%)
Query: 375 VDVVRTDSHLDFYEDTRNLAR-------MSDILAVYAWVDPATGYCQGMSDLLSPFVVIF 427
+DV+ D H F ++R + +L Y P GYCQ + + + V++
Sbjct: 151 LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLM 208
Query: 428 EDNAD-AFWCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESL 486
A+ AFWC + + + E + L+ +L+ HLS+ + L
Sbjct: 209 HMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPL 268
Query: 487 HFAFRMLLVLFRRELSFNEALSMWEMMW 514
+ + F R L ++ L +W+M +
Sbjct: 269 LYMTEWFMCAFSRTLPWSSVLRVWDMFF 296
>TB10_MOUSE (P58802) TBC1 domain family member 10 (EBP50-PDX
interactor of 64 kDa) (EPI64 protein)
Length = 500
Score = 43.9 bits (102), Expect = 0.001
Identities = 32/148 (21%), Positives = 60/148 (39%), Gaps = 10/148 (6%)
Query: 375 VDVVRTDSHLDFYEDTRNLAR-------MSDILAVYAWVDPATGYCQGMSDLLSPFVVIF 427
+DV+ D H F ++R + +L Y P GYCQ + + + V++
Sbjct: 151 LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLM 208
Query: 428 EDNAD-AFWCFEMLLRRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAESL 486
A+ AFWC + + + E + L+ +L+ HLS+ + L
Sbjct: 209 HMPAEQAFWCLVQVCEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPL 268
Query: 487 HFAFRMLLVLFRRELSFNEALSMWEMMW 514
+ + F R L ++ L +W+M +
Sbjct: 269 LYMTEWFMCAFARTLPWSSVLRVWDMFF 296
>TBC8_HUMAN (O95759) TBC1 domain family member 8 (Vascular
Rab-GAP/TBC-containing protein) (AD 3)
Length = 897
Score = 41.6 bits (96), Expect = 0.007
Identities = 35/142 (24%), Positives = 63/142 (43%), Gaps = 13/142 (9%)
Query: 373 IVVDVVRTDSHLDF-----YEDTRNLARMSDILAVYAWVDPATGYCQGMSDLLSPFVVIF 427
+V + + D H +++ +A + +L YA +P GYCQ M ++L+ ++++
Sbjct: 302 LVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSM-NILTSVLLLY 360
Query: 428 EDNADAFWCFEMLLRRMRE---NFQMEGPTRVMKQLREL--WHILELADKEMFAHLSKIG 482
+AFW + RM N ++ G EL H+ ELA E LS +
Sbjct: 361 TKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELA--EHMNDLSALA 418
Query: 483 AESLHFAFRMLLVLFRRELSFN 504
+ SL + + L + E + N
Sbjct: 419 SVSLSWFLTLFLSIMPLESAVN 440
>US6L_MOUSE (Q80XC3) USP6 N-terminal like protein
Length = 819
Score = 41.2 bits (95), Expect = 0.010
Identities = 32/148 (21%), Positives = 63/148 (41%), Gaps = 6/148 (4%)
Query: 370 LHRIVVDVVRTDSHLDFYEDTRNLARMS--DILAVYAWVDPATGYCQGMSDLLSPFVVIF 427
+ +I +DV RT + D + + S +LA Y+ + GYCQGMS ++ ++++
Sbjct: 141 IRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQ-ITALLLMY 199
Query: 428 EDNADAFWCFEMLL---RRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAE 484
+ DAFW L + F ++G ++++ IL ++ HL
Sbjct: 200 MNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIY 259
Query: 485 SLHFAFRMLLVLFRRELSFNEALSMWEM 512
+ + + F F L +W++
Sbjct: 260 TSFYTMKWFFQCFLDRTPFRLNLRIWDI 287
>US6L_HUMAN (Q92738) USP6 N-terminal like protein (Related to the N
terminus of tre) (RN-tre)
Length = 828
Score = 41.2 bits (95), Expect = 0.010
Identities = 32/148 (21%), Positives = 63/148 (41%), Gaps = 6/148 (4%)
Query: 370 LHRIVVDVVRTDSHLDFYEDTRNLARMS--DILAVYAWVDPATGYCQGMSDLLSPFVVIF 427
+ +I +DV RT + D + + S +LA Y+ + GYCQGMS ++ ++++
Sbjct: 141 IRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQ-ITALLLMY 199
Query: 428 EDNADAFWCFEMLL---RRMRENFQMEGPTRVMKQLRELWHILELADKEMFAHLSKIGAE 484
+ DAFW L + F ++G ++++ IL ++ HL
Sbjct: 200 MNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIY 259
Query: 485 SLHFAFRMLLVLFRRELSFNEALSMWEM 512
+ + + F F L +W++
Sbjct: 260 TSFYTMKWFFQCFLDRTPFTLNLRIWDI 287
>AZF1_YEAST (P41696) Asparagine-rich zinc finger protein AZF1
Length = 914
Score = 41.2 bits (95), Expect = 0.010
Identities = 27/113 (23%), Positives = 52/113 (45%), Gaps = 2/113 (1%)
Query: 552 DSDDGSVKSGSQSNHNENDNDNTKASQQSNHENTDVSVWDAKLKSLSSYPFCGLARNMWP 611
D+DDG+ S +N+N N+N+N + + +N++N D S+ A ++ + LA
Sbjct: 353 DNDDGN--DSSNNNNNNNNNNNNENNNDNNNDNNDNSINSATSTNIPNQEDHSLASTDTT 410
Query: 612 RNGRVQMSTMSSLTRKEKDELAIFCVAAILVLNRQKVIRETHSFDDMIKASAL 664
N R + + RK ++ + A L++ VI + + I S +
Sbjct: 411 SNSRKDLKEIEQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGM 463
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,345,379
Number of Sequences: 164201
Number of extensions: 3544174
Number of successful extensions: 11497
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 11190
Number of HSP's gapped (non-prelim): 232
length of query: 717
length of database: 59,974,054
effective HSP length: 117
effective length of query: 600
effective length of database: 40,762,537
effective search space: 24457522200
effective search space used: 24457522200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Lotus: description of TM0106.7