BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0103.10
         (418 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

SIL3_HUMAN (O60292) Signal-induced proliferation-associated 1 li...    36  0.16
BRF3_HUMAN (Q9ULD4) Bromodomain and PHD finger-containing protei...    35  0.27
SMOO_HUMAN (P53814) Smoothelin                                         35  0.36
SECD_MYCTU (Q50634) Protein-export membrane protein secD               33  1.0
GAT4_XENLA (Q91677) Transcription factor xGATA-4 (GATA binding f...    33  1.4
DRPL_HUMAN (P54259) Atrophin-1 (Dentatorubral-pallidoluysian atr...    33  1.4
SOC7_MOUSE (Q8VHQ2) Suppressor of cytokine signaling 7                 33  1.8
SOC7_HUMAN (O14512) Suppressor of cytokine signaling 7 (SOCS-6) ...    33  1.8
TDR3_MOUSE (Q91W18) Tudor domain containing protein 3                  32  2.3
SPKC_SYNY3 (P74745) Serine/threonine-protein kinase C (EC 2.7.1.37)    32  2.3
PUM1_MOUSE (Q80U78) Pumilio homolog 1                                  32  2.3
GUNC_PSEFL (P27033) Endoglucanase C precursor (EC 3.2.1.4) (Endo...    32  2.3
E2BD_YEAST (P12754) Translation initiation factor eIF-2B delta s...    32  2.3
ADG3_SCHPO (O74851) Adg3 protein precursor                             32  2.3
ABF1_MOUSE (Q61329) Alpha-fetoprotein enhancer binding protein (...    32  2.3
SX14_DROME (P40656) Putative transcription factor SOX-14               32  3.0
MUC1_HUMAN (P15941) Mucin 1 precursor (MUC-1) (Polymorphic epith...    32  3.0
ENDR_BOVIN (P07106) Endozepine-related protein precursor (Membra...    32  3.0
CN04_HUMAN (Q9H1B7) Protein C14orf4 (My039 protein)                    32  3.0
YL54_CAEEL (P34434) Hypothetical protein F44E2.4 in chromosome III     32  4.0

>SIL3_HUMAN (O60292) Signal-induced proliferation-associated 1 like
            protein 3 (Fragment)
          Length = 1368

 Score = 36.2 bits (82), Expect = 0.16
 Identities = 53/196 (27%), Positives = 79/196 (40%), Gaps = 30/196 (15%)

Query: 227  EKKNNVSFPPRINLKGDKASLLRIQAGRKRPLGEEDP--RPSPKRLNSGEPSGTIPAQHG 284
            EKK+ +S           AS L +  GR RPL   DP   P P      E S  + A   
Sbjct: 1198 EKKSTIS-----------ASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKA 1246

Query: 285  L-VDGSLSRPTVISSPLGPNLTSSANAPPPPVHTSTLSSGSVSRGFSCSLTL-TSAQMAR 342
              V  ++S  ++    L P++        PP H+   S  S+ RG     T  T ++   
Sbjct: 1247 YEVQRAVSLFSLNDPALSPDI--------PPAHSPVHSHLSLERGPPTPRTTPTMSEEPP 1298

Query: 343  MDEVVKQRGLDNISEGAVARVLHAFHCYRRSAQDADKLRSEVVRLRALNSQLAEDREVLA 402
            +D   K   L+      + + LH     ++  QD   L+SEV  LR  N +L E+ +  +
Sbjct: 1299 LDLTGKVYQLE-----VMLKQLHT--DLQKEKQDKVVLQSEVASLRQNNQRLQEESQAAS 1351

Query: 403  AQLIAKDNSFSKELAE 418
             QL      F +E  E
Sbjct: 1352 EQLRKFAEIFCREKKE 1367


>BRF3_HUMAN (Q9ULD4) Bromodomain and PHD finger-containing protein 3
           (Fragment)
          Length = 1214

 Score = 35.4 bits (80), Expect = 0.27
 Identities = 37/149 (24%), Positives = 58/149 (38%), Gaps = 8/149 (5%)

Query: 183 DPSEDSLTPEHKAVIDFLARLAVSDCSRVIGQTHRA----DEELLAAFEKKNNVSFPPRI 238
           DP   +  PE   + DF  R +  D   ++   +RA    + +L    EK + VS     
Sbjct: 712 DPERGTHLPESPKLEDFY-RFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSS 770

Query: 239 NLKGDKASLLRIQAGRKRPLGEEDPRPSPKRLNSGEPSGTIPA-QHGLVDGSLSRPTVIS 297
             +  +  LLR +    R    + P P P  LN    +G +PA   G  D ++    +  
Sbjct: 771 GARTRRVRLLRREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQG--DAAVLEQALQE 828

Query: 298 SPLGPNLTSSANAPPPPVHTSTLSSGSVS 326
            P        +  PPPP    T  + S+S
Sbjct: 829 EPEDDGDRDDSKLPPPPTLEPTGPAPSLS 857


>SMOO_HUMAN (P53814) Smoothelin
          Length = 917

 Score = 35.0 bits (79), Expect = 0.36
 Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)

Query: 259 GEEDPRPSPKRLNSGEP--SGTIPAQHG-----LVDGSLSRPTVISSPLGPNLTSSANAP 311
           G  +P PSP +  S EP  S T+P+  G     L+ G    P   S P GP+ T  A+  
Sbjct: 232 GSPEPPPSPPKTTSPEPQESPTLPSTEGQVVNKLLSGPKETPAAQSPPRGPSDTKRADVA 291

Query: 312 PP 313
            P
Sbjct: 292 GP 293


>SECD_MYCTU (Q50634) Protein-export membrane protein secD
          Length = 573

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 23/64 (35%), Positives = 29/64 (44%), Gaps = 5/64 (7%)

Query: 256 RPLGEE-DPRPSPKRLNSGEPSGTIPAQHGLV----DGSLSRPTVISSPLGPNLTSSANA 310
           +P  EE  P PS +    G+P+   PAQ G       G+  RP        PN TS A+ 
Sbjct: 128 QPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPASPQPGAQPRPYPQDPAPSPNPTSPASP 187

Query: 311 PPPP 314
           PP P
Sbjct: 188 PPAP 191


>GAT4_XENLA (Q91677) Transcription factor xGATA-4 (GATA binding
           factor-4)
          Length = 392

 Score = 33.1 bits (74), Expect = 1.4
 Identities = 25/76 (32%), Positives = 37/76 (47%), Gaps = 5/76 (6%)

Query: 7   TKSSKRNVVAATPLRASSPLERPWLRPKDDFVGAPHFFYVYGYMFPNLKIKFPFSPFICS 66
           T  S R V  ++PL  S+     + R     +GA +      YM P++   +  SPF  S
Sbjct: 100 TAPSSREVSYSSPLGISANGREQYSRG----LGATYASPYPAYMSPDMGAAWTASPFDSS 155

Query: 67  VLHNI-NVAPSQLHPN 81
           +LHN+ N A +  HPN
Sbjct: 156 MLHNLQNRAVTSRHPN 171


>DRPL_HUMAN (P54259) Atrophin-1 (Dentatorubral-pallidoluysian
           atrophy protein)
          Length = 1185

 Score = 33.1 bits (74), Expect = 1.4
 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 10/91 (10%)

Query: 256 RPLGEEDPRPSPKRLNSGEPSGTIPAQH-------GLVDGSLSRPTVISSPLG-PNLTSS 307
           RPL       SP  L +    G +P+ H       GL  G    PT+  SP   P  +SS
Sbjct: 308 RPLNNASA--SPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365

Query: 308 ANAPPPPVHTSTLSSGSVSRGFSCSLTLTSA 338
           A APP     S+ SS S +   S S + +SA
Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSA 396


>SOC7_MOUSE (Q8VHQ2) Suppressor of cytokine signaling 7
          Length = 579

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 18/89 (20%)

Query: 232 VSFPPRINLKGDKASLLRIQAGRKRPLGEEDPRPSPKRLNS----GEPSGTIPAQHGLVD 287
           VSF P     G+  SL+ +   ++       P P P    S     + SGT+P       
Sbjct: 275 VSFSPLFT--GETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPT------ 326

Query: 288 GSLSRPTVISSPLGPNLTSSANAPPPPVH 316
                 +V+ +P+G +L S    PPPP H
Sbjct: 327 ------SVLVAPMGSSLQSFPLPPPPPPH 349


>SOC7_HUMAN (O14512) Suppressor of cytokine signaling 7 (SOCS-6)
           (Nck, Ash and phospholipase C gamma-binding protein)
           (Nck-associated protein 4) (NAP-4) (Fragment)
          Length = 485

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 18/89 (20%)

Query: 232 VSFPPRINLKGDKASLLRIQAGRKRPLGEEDPRPSPKRLNS----GEPSGTIPAQHGLVD 287
           VSF P     G+  SL+ +   ++       P P P    S     + SGT+P       
Sbjct: 154 VSFSPLFT--GETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPT------ 205

Query: 288 GSLSRPTVISSPLGPNLTSSANAPPPPVH 316
                 +V+ +P+G +L S    PPPP H
Sbjct: 206 ------SVLVAPMGSSLQSFPLPPPPPPH 228


>TDR3_MOUSE (Q91W18) Tudor domain containing protein 3
          Length = 650

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 11/76 (14%)

Query: 258 LGEEDPRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPP---- 313
           L  E+P+  P+ L+ G+  G    Q+G+ DGS SR    +    P      N  PP    
Sbjct: 284 LNVEEPKSQPQHLHQGQHRGWNAEQNGMKDGSQSRHLPRNDTRQPR-----NERPPRFQK 338

Query: 314 --PVHTSTLSSGSVSR 327
             P   ST+ +  +SR
Sbjct: 339 DTPTSKSTVENSVLSR 354


>SPKC_SYNY3 (P74745) Serine/threonine-protein kinase C (EC 2.7.1.37)
          Length = 535

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 18/53 (33%), Positives = 22/53 (40%)

Query: 263 PRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPPPV 315
           P P PK   S  P  T+P Q        +   VI  P  P+  +  N P PPV
Sbjct: 473 PAPVPKPSPSPTPKPTVPPQISPTPQPSNTVPVIPPPENPSAETEPNLPAPPV 525


>PUM1_MOUSE (Q80U78) Pumilio homolog 1
          Length = 1189

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 7/119 (5%)

Query: 253 GRKRPLGEEDPRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPP 312
           G  RPLG + P+P P++    +PS  + +     + SLS  +  SS         AN   
Sbjct: 619 GPFRPLGTQQPQPQPQQ----QPSNNLASSSFYGNNSLSSNSQSSSLFSQGSAQPANTSL 674

Query: 313 PPVHTSTLSS--GSVSRGFSCSL-TLTSAQMARMDEVVKQRGLDNISEGAVARVLHAFH 368
               +S+L +  GS   GF  ++    +   +R D +     L   +  ++A + H+F+
Sbjct: 675 GFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLAPIGHSFY 733


>GUNC_PSEFL (P27033) Endoglucanase C precursor (EC 3.2.1.4)
           (Endo-1,4-beta-glucanase) (Cellulase) (EGC)
           (Cellodextrinase C)
          Length = 748

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 280 PAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPPPVHTSTLSSGSVSRGFSCSLTLTSA 338
           PA +G+V GS S P+ ISS    + +SS+  PP    +S++ S S S   S S+  +S+
Sbjct: 219 PAPYGIVGGS-SSPSSISSSSVRSSSSSSVVPPSSSSSSSVPSSSCSSVSSSSVVSSSS 276


>E2BD_YEAST (P12754) Translation initiation factor eIF-2B delta
           subunit (eIF-2B GDP-GTP exchange factor) (Guanine
           nucleotide exchange factor subunit GCD2) (GCD complex
           subunit GCD2)
          Length = 651

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 266 SPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPPPVHTSTLSSGSV 325
           SPK          +P     + GS         P+GPN +S+ +A  P   T+TL + S 
Sbjct: 131 SPKTSRITAAGLMVPVVASALSGSNVLTASSLMPVGPNASSTVSASAPASTTTTLPASSA 190

Query: 326 SRGFSCSLTLTSAQMARMDEVVKQRGLD 353
           +     S   T+   A   E+      D
Sbjct: 191 ALSAGTSSASTNTPTAIQQEIASSNASD 218


>ADG3_SCHPO (O74851) Adg3 protein precursor
          Length = 1131

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 27/74 (36%), Positives = 40/74 (53%), Gaps = 7/74 (9%)

Query: 271 NSGEPSGTIPAQHGLVDGSLSRP---TVISSPLGPNLTSSANAPPPPVHTSTLSSGSVS- 326
           NSG  S +IP+     +G+ S     TV SS L P+LTSS +     +  S+ SS ++S 
Sbjct: 896 NSGSTSYSIPSSSSRNEGTTSYSSNITVTSSTLKPSLTSSVSTASSYI-ASSASSNTLST 954

Query: 327 --RGFSCSLTLTSA 338
             + FS S TL+ +
Sbjct: 955 EPKTFSSSSTLSES 968


>ABF1_MOUSE (Q61329) Alpha-fetoprotein enhancer binding protein (AT
           motif-binding factor) (AT-binding transcription factor
           1)
          Length = 3726

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 260 EEDPRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPPPVHTST 319
           EE+   SP    SG P+G    +    D +LS P++ +SPL PN+  + +  P    +++
Sbjct: 502 EEELEDSPSE-ESGPPAGGTTKK----DLALSNPSISNSPLMPNVLQTLSRGPASTTSNS 556

Query: 320 LSSGSVSRGFSCSLTLTSAQMARMDEVVKQRGLDNISEGA 359
            S+  V  G +    L+         V + R LD   E A
Sbjct: 557 ASNFVVFDGANRRSRLSFNSEGVRANVAEGRRLDFADESA 596


>SX14_DROME (P40656) Putative transcription factor SOX-14
          Length = 472

 Score = 32.0 bits (71), Expect = 3.0
 Identities = 17/57 (29%), Positives = 25/57 (43%)

Query: 263 PRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSANAPPPPVHTST 319
           P PSP    S  P+ T  AQ      +++ P  ++SP  P   ++   P  P   ST
Sbjct: 58  PSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEPRST 114


>MUC1_HUMAN (P15941) Mucin 1 precursor (MUC-1) (Polymorphic
           epithelial mucin) (PEM) (PEMT) (Episialin)
           (Tumor-associated mucin) (Carcinoma-associated mucin)
           (Tumor-associated epithelial membrane antigen) (EMA)
           (H23AG) (Peanut-reactive urinary mucin) (PUM)
          Length = 1255

 Score = 32.0 bits (71), Expect = 3.0
 Identities = 21/59 (35%), Positives = 28/59 (46%), Gaps = 7/59 (11%)

Query: 275 PSGTIPAQHGLVDGSLSRPTVISS-PLGPNLTSSANAPP------PPVHTSTLSSGSVS 326
           P  T P  HG+     +RP   S+ P    +TS+ +  P      PPVH  T +SGS S
Sbjct: 908 PGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGSTAPPVHNVTSASGSAS 966


>ENDR_BOVIN (P07106) Endozepine-related protein precursor
           (Membrane-associated diazepam binding inhibitor)
           (MA-DBI)
          Length = 533

 Score = 32.0 bits (71), Expect = 3.0
 Identities = 17/42 (40%), Positives = 22/42 (51%), Gaps = 1/42 (2%)

Query: 110 RVSVQP-SPQRSWVSLEARPGRQRFNPIWPSITIALAHKFFR 150
           + S QP SP+ SW   E  PG   F  IWP I   L H +++
Sbjct: 485 QTSNQPTSPRPSWWPFEMSPGALTFAIIWPFIAQWLVHLYYQ 526


>CN04_HUMAN (Q9H1B7) Protein C14orf4 (My039 protein)
          Length = 796

 Score = 32.0 bits (71), Expect = 3.0
 Identities = 32/115 (27%), Positives = 43/115 (36%), Gaps = 22/115 (19%)

Query: 224 AAFEKKNNVSFPPRINLKGDKASLLRIQAGRKRPLGEEDPRP--SPKRLNSGEPSGTIPA 281
           AA E+++   +PP     G  +   R+  G   P G   P P   P  LN   P+ +  A
Sbjct: 163 AAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAA 222

Query: 282 --------QHGLVDGSLSRPTVISSP---LGPNL---------TSSANAPPPPVH 316
                    HG +   L  P     P   + PNL          S+A  PPPP H
Sbjct: 223 ASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPH 277


>YL54_CAEEL (P34434) Hypothetical protein F44E2.4 in chromosome III
          Length = 1283

 Score = 31.6 bits (70), Expect = 4.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 29/128 (22%)

Query: 258 LGEED--PRPSPKRLNSGEPSGTIPAQHGLVDGSLSRPTVISSPLGPNLTSSA-----NA 310
           LGEE+  PR  P  L+             ++   ++RPT ++ P  P   ++      +A
Sbjct: 598 LGEEEGCPRDPPANLDE------------IISRPVARPTPVTMP--PRAPTAKPLPIPSA 643

Query: 311 PPPPVHTSTLSSGSVSRGFSCSLTLTSAQMARMDEVVKQRGLDNISEGAVARVLHAFHCY 370
           P PPV +S  S     +   C   LTS Q   +  +   R +D   E        AFH +
Sbjct: 644 PTPPVASSKCSIEDQKKFEECVKPLTSFQPHPLSVIAIPRDIDQACE--------AFHTF 695

Query: 371 RRSAQDAD 378
           +  + +++
Sbjct: 696 KACSAESN 703


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.320    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,128,040
Number of Sequences: 164201
Number of extensions: 2321507
Number of successful extensions: 6588
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 6539
Number of HSP's gapped (non-prelim): 85
length of query: 418
length of database: 59,974,054
effective HSP length: 113
effective length of query: 305
effective length of database: 41,419,341
effective search space: 12632899005
effective search space used: 12632899005
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)