BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0100a.4
(445 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
GDIA_RAT (P50398) Rab GDP dissociation inhibitor alpha (Rab GDI ... 526 e-149
GDIA_CANFA (O97555) Rab GDP dissociation inhibitor alpha (Rab GD... 526 e-149
GDIA_PANTR (P60028) Rab GDP dissociation inhibitor alpha (Rab GD... 525 e-149
GDIA_HUMAN (P31150) Rab GDP dissociation inhibitor alpha (Rab GD... 525 e-149
GDIA_BOVIN (P21856) Rab GDP dissociation inhibitor alpha (Rab GD... 525 e-149
GDIA_PONPY (Q7YQM0) Rab GDP dissociation inhibitor alpha (Rab GD... 525 e-148
GDIA_MOUSE (P50396) Rab GDP dissociation inhibitor alpha (Rab GD... 525 e-148
GDIB_HUMAN (P50395) Rab GDP dissociation inhibitor beta (Rab GDI... 515 e-146
GDIC_MOUSE (Q61598) Rab GDP dissociation inhibitor beta-2 (Rab G... 509 e-144
GDIB_CANFA (O97556) Rab GDP dissociation inhibitor beta (Rab GDI... 506 e-143
YD4C_SCHPO (Q10305) Putative secretory pathway GDP dissociation ... 501 e-141
GDIB_MOUSE (P50397) Rab GDP dissociation inhibitor beta (Rab GDI... 497 e-140
GDIC_RAT (P50399) Rab GDP dissociation inhibitor beta-2 (Rab GDI... 496 e-140
GDI1_YEAST (P39958) Secretory pathway GDP dissociation inhibitor 470 e-132
RAE2_MOUSE (Q9QZD5) Rab proteins geranylgeranyltransferase compo... 128 3e-29
RAEP_YEAST (P32864) Rab proteins geranylgeranyltransferase compo... 123 8e-28
RAE2_HUMAN (P26374) Rab proteins geranylgeranyltransferase compo... 120 9e-27
RAE1_HUMAN (P24386) Rab proteins geranylgeranyltransferase compo... 114 4e-25
RAE1_MOUSE (Q9QXG2) Rab proteins geranylgeranyltransferase compo... 111 3e-24
RAE1_RAT (P37727) Rab proteins geranylgeranyltransferase compone... 108 4e-23
>GDIA_RAT (P50398) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1)
Length = 447
Score = 526 bits (1355), Expect = e-149
Identities = 253/432 (58%), Positives = 332/432 (76%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+D+ F I D YEP +D + F S SYDATTHFETT D+
Sbjct: 359 TAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGSAFD 430
>GDIA_CANFA (O97555) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1)
Length = 447
Score = 526 bits (1354), Expect = e-149
Identities = 252/432 (58%), Positives = 332/432 (76%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSF+Y GKIYKVP
Sbjct: 61 GPPEAMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFIYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQSTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+D+ F I D YEP +D + F S SYDATTHFETT D+
Sbjct: 359 TAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGSAFD 430
>GDIA_PANTR (P60028) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1)
Length = 447
Score = 525 bits (1353), Expect = e-149
Identities = 254/432 (58%), Positives = 330/432 (75%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + V RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T PE E++P ++LL P+D+ F I D YEP +D F S SYDATTHFETT D+
Sbjct: 359 TTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGTAFD 430
>GDIA_HUMAN (P31150) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1) (XAP-4) (Oligophrenin 2)
Length = 447
Score = 525 bits (1353), Expect = e-149
Identities = 254/432 (58%), Positives = 330/432 (75%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + V RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T PE E++P ++LL P+D+ F I D YEP +D F S SYDATTHFETT D+
Sbjct: 359 TTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGTAFD 430
>GDIA_BOVIN (P21856) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1) (SMG P25A GDI)
Length = 447
Score = 525 bits (1353), Expect = e-149
Identities = 253/432 (58%), Positives = 331/432 (76%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T PE E++P ++LL P+D+ F I D YEP +D + F S SYDATTHFETT D+
Sbjct: 359 TTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGSAFD 430
>GDIA_PONPY (Q7YQM0) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1)
Length = 447
Score = 525 bits (1352), Expect = e-148
Identities = 253/432 (58%), Positives = 330/432 (75%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+VR G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T PE E++P ++LL P+D+ F I D YEP +D F S SYDATTHFETT D+
Sbjct: 359 TTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGTAFD 430
>GDIA_MOUSE (P50396) Rab GDP dissociation inhibitor alpha (Rab GDI
alpha) (GDI-1)
Length = 447
Score = 525 bits (1352), Expect = e-148
Identities = 252/432 (58%), Positives = 332/432 (76%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
MDEEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S+S+ L +L+KRF+ +
Sbjct: 1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILE 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK V+GSFVY GKIYKVP
Sbjct: 61 GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMG+FEKRR RKF ++V +++ +DPK+ EG+D + R + K+ L D
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP + ++ GK +GV SEGE A+CK+++CDPSY+PD+V+ G+V
Sbjct: 240 RLSAIYGGTYMLNKPVDDIIMEN-GKVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ SYAHNVA +GKYIA +T E
Sbjct: 299 RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+D+ F I D YEP +D + F S SYDATTHFETT D+
Sbjct: 359 TAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMAGSAFD 430
>GDIB_HUMAN (P50395) Rab GDP dissociation inhibitor beta (Rab GDI
beta) (GDI-2)
Length = 445
Score = 515 bits (1327), Expect = e-146
Identities = 250/432 (57%), Positives = 326/432 (74%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
M+EEYDVIVLGTGL ECILSG++SV+G KVLHMDRN YYGG S S+ L L+KRF+
Sbjct: 1 MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
PE +G R++NVD+IPKF+MANG LV++L++T+VT+YL+FK +GSFVY GKIYKVP
Sbjct: 61 SPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMGLFEKRR RKF +YV +++ DP++ EG+D + T R + K+ L D
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP ++ + GK IGV SEGE A+CK+++CDPSY+ D+V VG+V
Sbjct: 240 RLSAIYGGTYMLNKPIEEIIVQN-GKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ S+AHNVA +GKYIA V+T E
Sbjct: 299 RVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+++ F I D P + FIS++YDATTHFETT D+
Sbjct: 359 TKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIK 418
Query: 420 EIYSKITGKVLD 431
IY ++TG D
Sbjct: 419 NIYKRMTGSEFD 430
>GDIC_MOUSE (Q61598) Rab GDP dissociation inhibitor beta-2 (Rab GDI
beta-2) (GDI-3)
Length = 445
Score = 509 bits (1311), Expect = e-144
Identities = 244/432 (56%), Positives = 328/432 (75%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
M+EEYDVIVLGTGL ECILSG++SV+G KVLHMD+N YYGG S S+ L L+KRF+
Sbjct: 1 MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPG 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
+ P +G R++NVD+IPKF+MANG LV++L+ T+VT+Y++FK ++GSFVY GKIYKVP
Sbjct: 61 QPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMGLFEKRR RKF +YV +++ DP++ EG+D + + R + K+ L D
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GH+LAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP ++ + GK +GV SEGE A+CK+++CDPSY+ D+V VG+V
Sbjct: 240 RLSAIYGGTYMLNKPIEEIIVQN-GKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ S+AHNVA +GKYIA V+T E
Sbjct: 299 RVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+++ F I D + P + FIS++YDATTHFETT D+
Sbjct: 359 TKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++TG D
Sbjct: 419 DIYKRMTGSEFD 430
>GDIB_CANFA (O97556) Rab GDP dissociation inhibitor beta (Rab GDI
beta) (GDI-2)
Length = 445
Score = 506 bits (1303), Expect = e-143
Identities = 246/432 (56%), Positives = 324/432 (74%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
M+EEYDVIVLGTGL ECILSG+++V+G KVLHMDRN YYGG S S+ L L+KRF+
Sbjct: 1 MNEEYDVIVLGTGLTECILSGIMTVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
P +G R++N+D+IPKF+MANG LV++L++T+VT+YL+FK +GSFVY GKIYKVP
Sbjct: 61 APPASMGRGRDWNLDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMGLFEKRR RKF +YV +++ DP++ EG+D + ++ K+ L D
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTAIGEVYKKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCCETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP ++ + GK IGV SEGE A+CK+++CDPSY+ D+V VG+V
Sbjct: 240 RLSAIYGGTYMLNKPIEEIIVQN-GKVIGVKSEGEVARCKQLICDPSYVKDRVEKVGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ S AHNVA +GKYIA V+T AE
Sbjct: 299 RVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISSAHNVAAQGKYIAIVSTTAE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+++ F I D P + FIS++YDATTHFETT D+
Sbjct: 359 TKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIK 418
Query: 420 EIYSKITGKVLD 431
IY ++TG D
Sbjct: 419 NIYKRMTGSEFD 430
>YD4C_SCHPO (Q10305) Putative secretory pathway GDP dissociation
inhibitor
Length = 440
Score = 501 bits (1290), Expect = e-141
Identities = 244/432 (56%), Positives = 322/432 (74%), Gaps = 1/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQLWKRFRGDDK 60
MDEEYDVIVLGTGL EC+LSGLLSVDG KVLH+DRNDYYG S SLNLTQL+ FR ++
Sbjct: 1 MDEEYDVIVLGTGLTECVLSGLLSVDGKKVLHIDRNDYYGADSASLNLTQLYALFRPGEQ 60
Query: 61 SPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPA 120
PE LG R++ VD++PKF+MANG L +LI+TDVT+Y+ FK + GS+VY G+I KVP
Sbjct: 61 RPESLGRDRDWCVDLVPKFLMANGDLTNILIYTDVTRYIEFKQIAGSYVYRDGRIAKVPG 120
Query: 121 TDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDDT 180
++EALKSPLM LFEKRRA+KF +V +Y DP +++ +++++ + + K+GL+ T
Sbjct: 121 NEMEALKSPLMSLFEKRRAKKFLEWVNNYREDDPSTYKDINIDRDSMESVFKKFGLQSGT 180
Query: 181 IDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFAR 240
DFIGHA+AL+LDD+YL PA++ ERI +YA S+A+F G SPYIYPLYGLGELPQ FAR
Sbjct: 181 QDFIGHAMALYLDDAYLKKPARETRERILLYASSIAKF-GKSPYIYPLYGLGELPQGFAR 239
Query: 241 LSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVAR 300
LSA+YGGTYMLN+P ++ + G AIGV S + AK K+++ DPSY +KVR+VG++ R
Sbjct: 240 LSAIYGGTYMLNQPVDEIVYGDDGVAIGVRSGDQVAKAKQIIGDPSYFREKVRSVGRLVR 299
Query: 301 AICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAET 360
AICI++HPIP+T++ S Q+I+PQ Q+ RK D+Y+ S HNV PKG Y+A ++T ET
Sbjct: 300 AICILNHPIPNTDNLDSVQIIIPQNQVKRKHDIYIAGISSVHNVCPKGYYLAIISTIVET 359
Query: 361 DQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVVE 420
P E+ PG+ LLGPV E+F + + YEP D D C+ISKS DAT+HFET DV +
Sbjct: 360 ANPLSEIAPGLKLLGPVVESFSRVQEIYEPVTDGTKDQCYISKSVDATSHFETLTCDVRD 419
Query: 421 IYSKITGKVLDL 432
IY ++TG L L
Sbjct: 420 IYKRMTGTDLVL 431
>GDIB_MOUSE (P50397) Rab GDP dissociation inhibitor beta (Rab GDI
beta) (GDI-2)
Length = 445
Score = 497 bits (1280), Expect = e-140
Identities = 243/432 (56%), Positives = 321/432 (74%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
M+EEYDVIVLG ECILSG++SV+G KVLHMDRN YYGG S S+ L L+KRF+
Sbjct: 1 MNEEYDVIVLGHTGTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
P +G R++NVD+IPKF+MANG LV++L+ T+VT+YL+FK +GSFVY GKIYKVP
Sbjct: 61 APPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYLDFKVTEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMGLFEKRR RKF +YV +++ +DP++ EG+D + + R++ K+ L D
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDENDPRTFEGIDPKKTSMREVYKKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GHALAL+ D YLD P + + RIK+Y+ESLAR+ G SPY+YPLYGLGELPQ FA
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCCETINRIKLYSESLARY-GKSPYLYPLYGLGELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP ++ + GK IGV SEGE A+CK+++CDPSY+ D+V VG+V
Sbjct: 240 RLSAIYGGTYMLNKPIEEIIMQN-GKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ S AHNVA +GKYIA +T E
Sbjct: 299 RVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISSAHNVAAQGKYIAIASTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+++ F I D P + FIS++YDATTHFETT D+
Sbjct: 359 TKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++ G D
Sbjct: 419 DIYKRMMGSEFD 430
>GDIC_RAT (P50399) Rab GDP dissociation inhibitor beta-2 (Rab GDI
beta-2) (GDI-3)
Length = 445
Score = 496 bits (1278), Expect = e-140
Identities = 239/432 (55%), Positives = 323/432 (74%), Gaps = 3/432 (0%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLN-LTQLWKRFRGDD 59
M+EEYDVIVLGTGL ECILSG++SV+G KVLHMD+N YYGG S S+ L L+KRF+
Sbjct: 1 MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPG 60
Query: 60 KSPEHLGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVP 119
+ P +G R++NVD+IPKF+MANG LV++L+ T+VT+Y++FK ++GSFVY GKIYKVP
Sbjct: 61 QPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVP 120
Query: 120 ATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDD 179
+T+ EAL S LMGLFEKRR RKF +YV +++ DP++ EG+D + + R + K+ L D
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQD 180
Query: 180 TIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFA 239
IDF GH+LAL+ D YLD P + + + Y+ESLAR+ G SPY+YPLYG ELPQ FA
Sbjct: 181 VIDFTGHSLALYRTDDYLDQPCCERLTELNFYSESLARY-GKSPYLYPLYGPWELPQGFA 239
Query: 240 RLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNVGKVA 299
RLSA+YGGTYMLNKP ++ + GK +GV SEGE A+CK+++CDPSY+ D+V VG+V
Sbjct: 240 RLSAIYGGTYMLNKPIEEIIVQN-GKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVI 298
Query: 300 RAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAE 359
R ICI+SHPI +TND++S Q+I+PQ Q+ RKSD+Y+ S+AHNVA +GKYIA V+T E
Sbjct: 299 RVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVE 358
Query: 360 TDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETTVKDVV 419
T +PE E++P ++LL P+++ F I D + P + FIS++YDATTHFETT D+
Sbjct: 359 TKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIK 418
Query: 420 EIYSKITGKVLD 431
+IY ++TG D
Sbjct: 419 DIYKRMTGSEFD 430
>GDI1_YEAST (P39958) Secretory pathway GDP dissociation inhibitor
Length = 451
Score = 470 bits (1209), Expect = e-132
Identities = 228/438 (52%), Positives = 322/438 (73%), Gaps = 7/438 (1%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQLWKRFRGDDK 60
+D +YDVIVLGTG+ ECILSGLLSVDG KVLH+D+ D+YGG + S+ L+QL+++F+ +
Sbjct: 6 IDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVTLSQLYEKFKQNPI 65
Query: 61 SPEH----LGSSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIY 116
S E G R++NVD+IPKF+MANG L +LIHTDVT+Y++FK V GS+V+ +GKIY
Sbjct: 66 SKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDFKQVSGSYVFKQGKIY 125
Query: 117 KVPATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGL 176
KVPA ++EA+ SPLMG+FEKRR +KF ++ Y+ D +H+GLDL++ T ++ K+GL
Sbjct: 126 KVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNTMDEVYYKFGL 185
Query: 177 EDDTIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQ 236
+ T +FIGHA+AL +D YL PA+ ERI +Y +S+AR+ G SPY+YP+YGLGELPQ
Sbjct: 186 GNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARY-GKSPYLYPMYGLGELPQ 244
Query: 237 AFARLSAVYGGTYMLNKPECKVEF-DSAGKAIGVTSEGETAKCKKVVCDPSYLPDKVRNV 295
FARLSA+YGGTYML+ P +V + GK GV ++ T K V+ DP+Y P+K ++
Sbjct: 245 GFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKST 304
Query: 296 G-KVARAICIMSHPIPDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFV 354
G +V RAICI++HP+P+T+++ S Q+I+PQ QLGRKSD+Y+ S AHNV KG Y+A +
Sbjct: 305 GQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLAII 364
Query: 355 TTEAETDQPEVELKPGIDLLGPVDETFYDIYDRYEPTNDHAADGCFISKSYDATTHFETT 414
+T ETD+P +EL+P LLGP++E F I + +EP D + D ++S+SYDA++HFE+
Sbjct: 365 STIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESM 424
Query: 415 VKDVVEIYSKITGKVLDL 432
DV +IY ++TG L L
Sbjct: 425 TDDVKDIYFRVTGHPLVL 442
>RAE2_MOUSE (Q9QZD5) Rab proteins geranylgeranyltransferase
component A 2 (Rab escort protein 2) (REP-2)
(Choroideraemia-like protein)
Length = 621
Score = 128 bits (321), Expect = 3e-29
Identities = 92/313 (29%), Positives = 157/313 (49%), Gaps = 15/313 (4%)
Query: 68 SREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPATDVEALK 127
SR FN+D++ K + + G+L+ +LI ++V++Y FK V + +GK+ +VP + +
Sbjct: 225 SRRFNIDLVSKPLYSQGSLIDLLIKSNVSRYAEFKNVTRILAFWEGKVEQVPCSRADVFN 284
Query: 128 SPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDDTIDFIGHA 187
S + + EKR KF + DYE S E D Q + + L + FI H+
Sbjct: 285 SKELSMVEKRMLMKFLTFCLDYE---QHSDEYQDFKQCSFSDYLKTKKLTPNLQHFILHS 341
Query: 188 LALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFARLSAVYGG 247
+A+ + S D ++ K + + L RF G +P+I+PLYG GE+PQ F R+ AV+GG
Sbjct: 342 IAMTSESS---CTTLDGLQATKNFLQCLGRF-GNTPFIFPLYGHGEIPQCFCRMCAVFGG 397
Query: 248 TYML-NKPECKVEFDSAGKAIGVTSE-GETAKCKKVVCDPSYLP-DKVRNV--GKVARAI 302
Y L +K +C V +G+ G+ G+ + + SYLP + NV +++RA+
Sbjct: 398 VYCLRHKVQCLVVDKDSGRCKGIIDAFGQRISANYFIVEDSYLPKETCSNVQYKQISRAV 457
Query: 303 CIMSHPIPDT-NDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVTTEAETD 361
I I T +D + +++P + G S + CS + K Y+ +T +
Sbjct: 458 LITDQSILKTDSDQQISILVVPPLEPGTTSVRVMELCS-STMTCMKDSYLVHLTCSSSKT 516
Query: 362 QPEVELKPGIDLL 374
E +L+P + L
Sbjct: 517 ARE-DLEPVVKQL 528
Score = 50.4 bits (119), Expect = 9e-06
Identities = 23/48 (47%), Positives = 31/48 (63%)
Query: 4 EYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL 51
E+DV+++GTGL E IL+ S G +VLH+D YYGG S + T L
Sbjct: 8 EFDVVIIGTGLPESILAAACSRSGQRVLHVDSRSYYGGNWASFSFTGL 55
>RAEP_YEAST (P32864) Rab proteins geranylgeranyltransferase
component A (Rab escort protein) (REP)
Length = 603
Score = 123 bits (309), Expect = 8e-28
Identities = 103/402 (25%), Positives = 179/402 (43%), Gaps = 43/402 (10%)
Query: 3 EEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL--WKRFRGDDK 60
++ DV++ GTG+ E +L+ L+ G VLH+D+NDYYG S +L + Q+ W +
Sbjct: 45 DKVDVLIAGTGMVESVLAAALAWQGSNVLHIDKNDYYGDTSATLTVDQIKRWVNEVNEGS 104
Query: 61 SPEHLG--------------SSREFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDG 106
+ SSR+F +D+ PK + A L+ +LI + V +YL F+++
Sbjct: 105 VSCYKNAKLYVSTLIGSGKYSSRDFGIDLSPKILFAKSDLLSILIKSRVHQYLEFQSLSN 164
Query: 107 SFVYNKGKIYKVPATDVEALKSPLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVT 166
Y K+ T E + L KR KF +V ++E ++ Q
Sbjct: 165 FHTYENDCFEKLTNTKQEIFTDQNLPLMTKRNLMKFIKFVLNWEAQ-------TEIWQPY 217
Query: 167 ARQLIS-----KYGLEDDTIDFIGHALALHLDDSYLDTPAKDFVERIKVYAESLARFQGG 221
A + +S K+ LE + + ++ L D L+ + ++RI+ Y S + G
Sbjct: 218 AERTMSDFLGEKFKLEKPQVFELIFSIGLCYD---LNVKVPEALQRIRRYLTSFDVY-GP 273
Query: 222 SPYIYPLY-GLGELPQAFARLSAVYGGTYMLNKPECKVEFDSAGKAIGVTSEGETAKCKK 280
P + Y G GEL Q F R +AV G TY LN E V F+ K + +K
Sbjct: 274 FPALCSKYGGPGELSQGFCRSAAVGGATYKLN--EKLVSFNPTTKVATFQDGSKVEVSEK 331
Query: 281 VVCDPSYLPDKVRNVG----KVARAICIMSHPIPD--TNDSHSAQVILPQKQL--GRKSD 332
V+ P+ P ++V +V R CI+ +P + +A V+ P L G K
Sbjct: 332 VIISPTQAPKDSKHVPQQQYQVHRLTCIVENPCTEWFNEGESAAMVVFPPGSLKSGNKEV 391
Query: 333 MYLFCCSYAHNVAPKGKYIAFVTTEAETDQPEVELKPGIDLL 374
+ F + P+G + +++T + + E+++ ++ +
Sbjct: 392 VQAFILGAGSEICPEGTIVWYLSTTEQGPRAEMDIDAALEAM 433
>RAE2_HUMAN (P26374) Rab proteins geranylgeranyltransferase
component A 2 (Rab escort protein 2) (REP-2)
(Choroideraemia-like protein)
Length = 656
Score = 120 bits (300), Expect = 9e-27
Identities = 84/305 (27%), Positives = 156/305 (50%), Gaps = 15/305 (4%)
Query: 69 REFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPATDVEALKS 128
R FN+D++ K + + G L+ +LI +DV++Y+ FK V + +GK+ +VP + + S
Sbjct: 227 RRFNIDLVSKLLYSQGLLIDLLIKSDVSRYVEFKNVTRILAFREGKVEQVPCSRADVFNS 286
Query: 129 PLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDDTIDFIGHAL 188
+ + EKR KF + +YE P ++ Q + + + L + F+ H++
Sbjct: 287 KELTMVEKRMLMKFLTFCLEYE-QHPDEYQA--FRQCSFSEYLKTKKLTPNLQHFVLHSI 343
Query: 189 ALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFARLSAVYGGT 248
A+ + S D + K + + L RF G +P+++PLYG GE+PQ F R+ AV+GG
Sbjct: 344 AMTSESS---CTTIDGLNATKNFLQCLGRF-GNTPFLFPLYGQGEIPQGFCRMCAVFGGI 399
Query: 249 YML-NKPECKVEFDSAGKAIGVTSE-GETAKCKKVVCDPSYLPDKV-RNV--GKVARAIC 303
Y L +K +C V +G+ + G+ K + + SYL ++ NV +++RA+
Sbjct: 400 YCLRHKVQCFVVDKESGRCKAIIDHFGQRINAKYFIVEDSYLSEETCSNVQYKQISRAVL 459
Query: 304 IMSHPIPDTN-DSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVT-TEAETD 361
I I T+ D ++ +I+P + G + CS + K Y+ +T + ++T
Sbjct: 460 ITDQSILKTDLDQQTSILIVPPAEPGACAVRVTELCS-STMTCMKDTYLVHLTCSSSKTA 518
Query: 362 QPEVE 366
+ ++E
Sbjct: 519 REDLE 523
Score = 48.9 bits (115), Expect = 3e-05
Identities = 22/48 (45%), Positives = 31/48 (63%)
Query: 4 EYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL 51
E+DV+++GTGL E IL+ S G +VLH+D YYGG S + + L
Sbjct: 8 EFDVVIIGTGLPESILAAACSRSGQRVLHIDSRSYYGGNWASFSFSGL 55
>RAE1_HUMAN (P24386) Rab proteins geranylgeranyltransferase
component A 1 (Rab escort protein 1) (REP-1)
(Choroideraemia protein) (TCD protein)
Length = 653
Score = 114 bits (286), Expect = 4e-25
Identities = 76/305 (24%), Positives = 155/305 (49%), Gaps = 15/305 (4%)
Query: 69 REFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPATDVEALKS 128
R FN+D++ K + + G L+ +LI ++V++Y FK + + +G++ +VP + + S
Sbjct: 225 RRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNS 284
Query: 129 PLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDDTIDFIGHAL 188
+ + EKR KF + +YE P ++G + ++T + + L + + H++
Sbjct: 285 KQLTMVEKRMLMKFLTFCMEYE-KYPDEYKGYE--EITFYEYLKTQKLTPNLQYIVMHSI 341
Query: 189 ALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFARLSAVYGGT 248
A+ S + D ++ K + L R+ G +P+++PLYG GELPQ F R+ AV+GG
Sbjct: 342 AM---TSETASSTIDGLKATKNFLHCLGRY-GNTPFLFPLYGQGELPQCFCRMCAVFGGI 397
Query: 249 YML-NKPECKVEFDSAGKAIGVTSE-GETAKCKKVVCDPSYLPDKVRN---VGKVARAIC 303
Y L + +C V + K + + G+ + + + SY P+ + + +++RA+
Sbjct: 398 YCLRHSVQCLVVDKESRKCKAIIDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVL 457
Query: 304 IMSHPIPDTNDSHSAQVI-LPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVT-TEAETD 361
I + T+ ++ +P ++ G + + CS + KG Y+ +T T ++T
Sbjct: 458 ITDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCS-STMTCMKGTYLVHLTCTSSKTA 516
Query: 362 QPEVE 366
+ ++E
Sbjct: 517 REDLE 521
Score = 49.3 bits (116), Expect = 2e-05
Identities = 23/51 (45%), Positives = 32/51 (62%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL 51
+ E+DVIV+GTGL E I++ S G +VLH+D YYGG S + + L
Sbjct: 5 LPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGL 55
>RAE1_MOUSE (Q9QXG2) Rab proteins geranylgeranyltransferase
component A 1 (Rab escort protein 1) (REP-1)
(Choroideraemia protein)
Length = 665
Score = 111 bits (278), Expect = 3e-24
Identities = 77/294 (26%), Positives = 147/294 (49%), Gaps = 16/294 (5%)
Query: 69 REFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPATDVEALKS 128
R FN+D++ K + + G L+ +LI ++V++Y FK + + +G + +VP + + S
Sbjct: 237 RRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSRADVFNS 296
Query: 129 PLMGLFEKRRARKFFIYVQDYEVSDPKSHEGLDLNQVTARQLISKYGLEDDTIDFIGHAL 188
+ + EKR KF + +YE P ++ + + T + + L + F+ H++
Sbjct: 297 KQLTMVEKRMLMKFLTFCVEYE-DHPDEYKAYE--ETTFSEYLKTQKLTPNLQYFVLHSI 353
Query: 189 ALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFARLSAVYGGT 248
A+ S + D ++ K + + L R+ G +P+++PLYG GELPQ F R+ AV+GG
Sbjct: 354 AM---TSETTSSTVDGLKATKKFLQCLGRY-GNTPFLFPLYGQGELPQCFCRMCAVFGGI 409
Query: 249 YML-NKPECKVEFDSAGKAIGVTSE-GETAKCKKVVCDPSYLPDKVRN---VGKVARAIC 303
Y L + +C V + K + + G+ K V + SYL + + +++RA+
Sbjct: 410 YCLRHSVQCLVVDKESRKCKAIVDQFGQRIISKHFVIEDSYLSENTCSGVQYRQISRAVL 469
Query: 304 IMSHPI--PDTNDSHSAQVILPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVT 355
I + PD +D + + +P ++ G + + CS + KG Y+ +T
Sbjct: 470 ITDGSVLKPD-SDQQVSILTVPAEESGSFAVRVIELCS-STMTCMKGTYLVHLT 521
Score = 48.1 bits (113), Expect = 4e-05
Identities = 22/51 (43%), Positives = 32/51 (62%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL 51
+ ++DVIV+GTGL E I++ S G +VLH+D YYGG S + + L
Sbjct: 5 LPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGL 55
>RAE1_RAT (P37727) Rab proteins geranylgeranyltransferase component
A 1 (Rab escort protein 1) (REP-1)
Length = 650
Score = 108 bits (269), Expect = 4e-23
Identities = 75/295 (25%), Positives = 145/295 (48%), Gaps = 18/295 (6%)
Query: 69 REFNVDMIPKFMMANGALVRVLIHTDVTKYLNFKAVDGSFVYNKGKIYKVPATDVEALKS 128
R FN+D++ + + + G L+ +LI ++V++Y FK + + +G + +VP + + S
Sbjct: 222 RRFNIDLVSQLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSRADVFNS 281
Query: 129 PLMGLFEKRRARKFFIYVQDYE--VSDPKSHEGLDLNQVTARQLISKYGLEDDTIDFIGH 186
+ + EKR KF + +YE + +++EG T + + L + F+ H
Sbjct: 282 KQLTMVEKRMLMKFLTFCVEYEEHPDEYRAYEG-----TTFSEYLKTQKLTPNLQYFVLH 336
Query: 187 ALALHLDDSYLDTPAKDFVERIKVYAESLARFQGGSPYIYPLYGLGELPQAFARLSAVYG 246
++A+ S + D ++ K + + L R+ G +P+++PLYG GELPQ F R+ AV+G
Sbjct: 337 SIAM---TSETTSCTVDGLKATKKFLQCLGRY-GNTPFLFPLYGQGELPQCFCRMCAVFG 392
Query: 247 GTYML-NKPECKVEFDSAGKAIGVTSE-GETAKCKKVVCDPSYLPDKVRN---VGKVARA 301
G Y L + +C V + K V + G+ K + + SYL + + +++RA
Sbjct: 393 GIYCLRHSVQCLVVDKESRKCKAVIDQFGQRIISKHFIIEDSYLSENTCSRVQYRQISRA 452
Query: 302 ICIMSHPIPDTNDSHSAQVI-LPQKQLGRKSDMYLFCCSYAHNVAPKGKYIAFVT 355
+ I + T+ ++ +P ++ G + CS + KG Y+ +T
Sbjct: 453 VLITDGSVLKTDADQQVSILAVPAEEPGSFGVRVIELCS-STMTCMKGTYLVHLT 506
Score = 48.1 bits (113), Expect = 4e-05
Identities = 22/51 (43%), Positives = 32/51 (62%)
Query: 1 MDEEYDVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYYGGASTSLNLTQL 51
+ ++DVIV+GTGL E I++ S G +VLH+D YYGG S + + L
Sbjct: 5 LPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGL 55
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.137 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,120,162
Number of Sequences: 164201
Number of extensions: 2406364
Number of successful extensions: 5509
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 5412
Number of HSP's gapped (non-prelim): 54
length of query: 445
length of database: 59,974,054
effective HSP length: 113
effective length of query: 332
effective length of database: 41,419,341
effective search space: 13751221212
effective search space used: 13751221212
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Lotus: description of TM0100a.4