BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0095c.5
         (423 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

HIAT_MOUSE (P70187) Hippocampus abundant transcript 1 protein          84  5e-16
HIAT_HUMAN (Q96MC6) Hippocampus abundant transcript 1 protein (P...    82  2e-15
TCR8_PASMU (P51564) Tetracycline resistance protein, class H (TE...    64  6e-10
TCR2_ECOLI (P02980) Tetracycline resistance protein, class B (TE...    60  1e-08
TCR4_SALOR (P33733) Tetracycline resistance protein, class D (TE...    59  2e-08
TCR1_ECOLI (P02982) Tetracycline resistance protein, class A (TE...    57  7e-08
TCR7_VIBAN (P51563) Tetracycline resistance protein, class G (TE...    55  4e-07
TCR5_ECOLI (Q07282) Tetracycline resistance protein, class E (TE...    53  1e-06
BMR2_BACSU (P39843) Multidrug resistance protein 2 (Multidrug-ef...    50  1e-05
TCR3_ECOLI (P02981) Tetracycline resistance protein, class C (TE...    49  2e-05
YMPB_CAEEL (Q7Z118) Hypothetical protein B0361.11 in chromosome III    42  0.004
OCTL_DROME (Q95R48) Organic cation transporter-like protein            42  0.004
NORA_STAAM (P21191) Quinolone resistance protein norA                  40  0.011
PMRA_LACLA (P58120) Multi-drug resistance efflux pump pmrA homolog     39  0.019
Y450_BUCAP (Q8K999) Hypothetical transport protein BUsg450             39  0.025
Y411_BUCBP (Q89AA9) Hypothetical transport protein bbp411              39  0.033
ARAJ_ECOLI (P23910) Protein araJ precursor                             38  0.056
CIT1_ECOLI (P07661) Citrate-proton symporter (Citrate transporte...    37  0.096
YCEI_BACSU (O34691) Hypothetical metabolite transport protein yceI     37  0.13
BMR1_BACSU (P33449) Multidrug resistance protein 1 (Multidrug-ef...    36  0.16

>HIAT_MOUSE (P70187) Hippocampus abundant transcript 1 protein
          Length = 490

 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 73/304 (24%), Positives = 132/304 (43%), Gaps = 35/304 (11%)

Query: 48  TCPKVIYI-NGLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQS 106
           T PK  ++ NGL Q + G+   +  PL+G LSD  GRK  LL+T+  T     ++     
Sbjct: 65  TFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISP- 123

Query: 107 EEFVYAYYVLRTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVL 166
               + Y+ + + S + +    F +  AYVAD+  E +R+  +  ++  F+AS V    +
Sbjct: 124 ----WWYFAVISVSGVFAV--TFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAI 177

Query: 167 ARFLPEEY------IFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHK 220
             +L + Y      +   +IALL  C     F LV      P+K + + +   +      
Sbjct: 178 GAYLGQMYGDSLVVVLATAIALLDIC-----FILVAVPESLPEKMRPASWGAPISWEQAD 232

Query: 221 RYKSMRNAAEILDNLIIAV-----------QY-----YLKAVFGFNKNQFSELLMMVGIG 264
            + S++   +    L+I +           QY     YLK +  F+    +  + ++GI 
Sbjct: 233 PFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLKQIMKFSPESVAAFIAVLGIL 292

Query: 265 SIFSQMVLLPILNPKVGEKVILSAALLASIAYAWLYGLAWAPWVPYFSASFGIIYVLVKP 324
           SI +Q ++L +L   +G K  +   L   I     YG    PW+ + + +   +  +  P
Sbjct: 293 SIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFP 352

Query: 325 SGKA 328
           +  A
Sbjct: 353 AVSA 356


>HIAT_HUMAN (Q96MC6) Hippocampus abundant transcript 1 protein
           (Putative tetracycline transporter-like protein)
          Length = 490

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 72/304 (23%), Positives = 131/304 (42%), Gaps = 35/304 (11%)

Query: 48  TCPKVIYI-NGLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQS 106
           T PK  ++ NGL Q + G+   +  PL+G LSD  GRK  LL+T+  T     ++     
Sbjct: 65  TFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISP- 123

Query: 107 EEFVYAYYVLRTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVL 166
               + Y+ + + S + +    F +  AYVAD+  E +R+  +  ++  F+AS V    +
Sbjct: 124 ----WWYFAVISVSGVFA--VTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAI 177

Query: 167 ARFLPEEY------IFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHK 220
             +L   Y      +   +IALL  C     F LV      P+K + + +   +      
Sbjct: 178 GAYLGRVYGDSLVVVLATAIALLDIC-----FILVAVPESLPEKMRPASWGAPISWEQAD 232

Query: 221 RYKSMRNAAEILDNLIIAV-----------QY-----YLKAVFGFNKNQFSELLMMVGIG 264
            + S++   +    L+I +           QY     YL+ +  F+    +  + ++GI 
Sbjct: 233 PFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGIL 292

Query: 265 SIFSQMVLLPILNPKVGEKVILSAALLASIAYAWLYGLAWAPWVPYFSASFGIIYVLVKP 324
           SI +Q ++L +L   +G K  +   L   I     YG    PW+ + + +   +  +  P
Sbjct: 293 SIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFP 352

Query: 325 SGKA 328
           +  A
Sbjct: 353 AVSA 356


>TCR8_PASMU (P51564) Tetracycline resistance protein, class H
           (TETA(H))
          Length = 400

 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 61/266 (22%), Positives = 117/266 (43%), Gaps = 27/266 (10%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +    +++  P+LG+LSD++GRKP+LL ++      + ++A+  +   ++  Y+ 
Sbjct: 44  GVLLALYATMQVIFAPILGRLSDKYGRKPILLFSLLGAALDYLLMAFSTT---LWMLYIG 100

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPE---- 172
           R  + I       C S   ++DV     R   F ++ G+F    ++G +L   L +    
Sbjct: 101 RIIAGITGATGAVCASA--MSDVTPAKNRTRYFGFLGGVFGVGLIIGPMLGGLLGDISAH 158

Query: 173 -EYIF-------VVSIALLTFCPVYMQFFLVETVTPAPK--KNQVSGFCTKVVDVLHKRY 222
             +IF       ++ ++LL F     +  LV   TP  +   N V+ F  K +      Y
Sbjct: 159 MPFIFAAISHSILLILSLLFFRETQKREALVANRTPENQTASNTVTVFFKKSLYFWLATY 218

Query: 223 KSMRNAAEILDNLIIAVQYYLKAVFGFNKNQFSELLMMVGIGSIFSQMVLLPILNPKVGE 282
             ++   +I   + +    Y    F +N       L ++G+  IF Q ++   L  K GE
Sbjct: 219 FIIQLIGQIPATIWVLFTQYR---FDWNTTSIGMSLAVLGVLHIFFQAIVAGKLAQKWGE 275

Query: 283 K----VILSAALLASIAYAWLYGLAW 304
           K    + +S  ++  +  AW+ G  W
Sbjct: 276 KTTIMISMSIDMMGCLLLAWI-GHVW 300


>TCR2_ECOLI (P02980) Tetracycline resistance protein, class B
           (TETA(B)) (Metal-tetracycline/H(+) antiporter)
          Length = 401

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 61/257 (23%), Positives = 114/257 (43%), Gaps = 22/257 (8%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +  + +++  P LG++SD  GR+P+LL+++      + +LA+  +   ++  Y+ 
Sbjct: 44  GVLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSA---LWMLYLG 100

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFL----PE 172
           R  S I   G+   ++ + +AD  + S+R   F W+   F    + G ++  F     P 
Sbjct: 101 RLLSGI--TGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPH 158

Query: 173 EYIFVVSIA-LLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKRYKSMRNAAEI 231
              F+ ++  ++TF  + + F+  ET       +   G  T+   V    +K+M     I
Sbjct: 159 SPFFIAALLNIVTF--LVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLII 216

Query: 232 LDNLIIAVQYYLKAVFGFNKNQFSELLMMVG--------IGSIFSQMVLLPILNPKVGEK 283
             +  +  Q        F +N+F    MMVG        + S+F   V   I   K GEK
Sbjct: 217 YFSAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIAT-KWGEK 275

Query: 284 VILSAALLA-SIAYAWL 299
             +    +A S A+A+L
Sbjct: 276 TAVLLGFIADSSAFAFL 292


>TCR4_SALOR (P33733) Tetracycline resistance protein, class D
           (TETA(D))
          Length = 394

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 62/265 (23%), Positives = 116/265 (43%), Gaps = 19/265 (7%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +  + ++   PLLG+ SD+ GR+P+LL++++   F + +LA       ++  Y+ 
Sbjct: 44  GILLALYAVMQVCFAPLLGRWSDKLGRRPVLLLSLAGAAFDYTLLA---LSNVLWMLYLG 100

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNV---LARFLPEE 173
           R  S I   G+   ++ + VAD    S+R A F  +   F A  + G     LA  +   
Sbjct: 101 RIISGI--TGATGAVAASVVADSTAVSERTAWFGRLGAAFGAGLIAGPAIGGLAGDISPH 158

Query: 174 YIFVVSIALLTFCPVYMQFFLVETVT-----PAPKKNQVSG--FCTKVVDVLHKRYKSMR 226
             FV++ A+L  C   M FF+ +        PA +K + +G  F T +  +    +    
Sbjct: 159 LPFVIA-AILNACTFLMVFFIFKPAVQTEEKPADEKQESAGISFITLLKPLALLLFVFF- 216

Query: 227 NAAEILDNLIIAV-QYYLKAVFGFNKNQFSELLMMVGIGSIFSQMVLLPILNPKVGEKVI 285
             A+++  +   V   + ++ F ++       L  +G      Q V+   L  ++ EK I
Sbjct: 217 -TAQLIGQIPATVWVLFTESRFAWDSAAVGFSLAGLGAMHALFQAVVAGALAKRLSEKTI 275

Query: 286 LSAALLASIAYAWLYGLAWAPWVPY 310
           + A  +A      L     + W+ Y
Sbjct: 276 IFAGFIADATAFLLMSAITSGWMVY 300


>TCR1_ECOLI (P02982) Tetracycline resistance protein, class A
           (TETA(A))
          Length = 399

 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 33/127 (25%), Positives = 66/127 (50%), Gaps = 9/127 (7%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +  + +    P+LG LSD  GR+P+LL++++     +A++A   +  F++  Y+ 
Sbjct: 46  GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMA---TAPFLWVLYIG 102

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFS----ASHVVGNVLARFLPE 172
           R  + I   G+   ++ AY+AD+ +  +RA  F +++  F     A  V+G ++  F P 
Sbjct: 103 RIVAGI--TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPH 160

Query: 173 EYIFVVS 179
              F  +
Sbjct: 161 APFFAAA 167


>TCR7_VIBAN (P51563) Tetracycline resistance protein, class G
           (TETA(G))
          Length = 393

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 37/144 (25%), Positives = 68/144 (46%), Gaps = 8/144 (5%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G   ++  + ++V  P+LGQLSD +GR+P+LL +++     + ++A   S   ++  Y+ 
Sbjct: 44  GALLSLYALMQVVFAPMLGQLSDSYGRRPVLLASLAGAAVDYTIMA---SAPVLWVLYIG 100

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFL---PEE 173
           R  S +   G+   ++ + +AD   E  RA  F ++   + A  + G  L   L      
Sbjct: 101 RLVSGV--TGATGAVAASTIADSTGEGSRARWFGYMGACYGAGMIAGPALGGMLGGISAH 158

Query: 174 YIFVVSIALLTFCPVYMQFFLVET 197
             F+ +  L  F  +    FL ET
Sbjct: 159 APFIAAALLNGFAFLLACIFLKET 182


>TCR5_ECOLI (Q07282) Tetracycline resistance protein, class E
           (TETA(E))
          Length = 405

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 59/273 (21%), Positives = 119/273 (42%), Gaps = 36/273 (13%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +  + +++  PLLG+ SD  GR+P+LL+++      +A++A   +   V+  Y+ 
Sbjct: 44  GVLLALYAMMQVIFAPLLGRWSDRIGRRPVLLLSLLGATLDYALMA---TASVVWVLYLG 100

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARF-----LP 171
           R  + I   G+   ++ + +ADV  E  R   F  +   F    + G V+  F     + 
Sbjct: 101 RLIAGI--TGATGAVAASTIADVTPEESRTHWFGMMGACFGGGMIAGPVIGGFAGQLSVQ 158

Query: 172 EEYIFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKRYKSMRNAAEI 231
             ++F  +I  L F  +   F L ET       NQVS       + +++   S+R     
Sbjct: 159 APFMFAAAINGLAF--LVSLFILHET----HNANQVSDELKN--ETINETTSSIREMISP 210

Query: 232 LDNLIIAVQYYLKAVFG---------FNKNQFSELLMMVGIG-SIFS------QMVLLPI 275
           L  L++   +++  + G         F + +F+   +MVG+  ++F       Q +    
Sbjct: 211 LSGLLVV--FFIIQLIGQIPATLWVLFGEERFAWDGVMVGVSLAVFGLTHALFQGLAAGF 268

Query: 276 LNPKVGEKVILSAALLASIAYAWLYGLAWAPWV 308
           +   +GE+  ++  +LA     +L  +    W+
Sbjct: 269 IAKHLGERKAIAVGILADGCGLFLLAVITQSWM 301


>BMR2_BACSU (P39843) Multidrug resistance protein 2
           (Multidrug-efflux transporter 2)
          Length = 400

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 72/333 (21%), Positives = 139/333 (41%), Gaps = 36/333 (10%)

Query: 65  IFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVLRTFSYIIS 124
           I +++  P  G+  D  GRK ++++ +   IFS + L +      V  +Y  R    + S
Sbjct: 56  ISQLITSPFAGRWVDRFGRKKMIILGL--LIFSLSELIFGLGTH-VSIFYFSRILGGV-S 111

Query: 125 QGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPE-----EYIFVVS 179
              I     AYVAD+    +R+    +++   S   ++G     F+        + F  +
Sbjct: 112 AAFIMPAVTAYVADITTLKERSKAMGYVSAAISTGFIIGPGAGGFIAGFGIRMPFFFASA 171

Query: 180 IALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKRYKSMRNAAEILDNLIIAV 239
           IAL+    V   F L E+++   +++Q+S   TK  + +    +S+     I   ++  +
Sbjct: 172 IALIA--AVTSVFILKESLS-IEERHQLSSH-TKESNFIKDLKRSIHPVYFIAFIIVFVM 227

Query: 240 QYYLKAV-----------FGFNKNQFSELLMMVGIGSIFSQMVLLPILNPKVGEKVILSA 288
            + L A            FGF     + ++ +  I ++  Q++L   L  K+GEK ++  
Sbjct: 228 AFGLSAYETVFSLFSDHKFGFTPKDIAAIITISSIVAVVIQVLLFGKLVNKLGEKRMIQL 287

Query: 289 ALLASIAYAWLYG-LAWAPWVPYFSASFGIIYVLVKP---------SGKAQTFIAGAQSI 338
            L+     A++   ++    V   +    + + L++P         +G  Q F+AG  S 
Sbjct: 288 CLITGAILAFVSTVMSGFLTVLLVTCFIFLAFDLLRPALTAHLSNMAGNQQGFVAGMNST 347

Query: 339 SDLLSPIAMSPLTS--WFLSSNAPFDCKGFSII 369
              L  I    L    + L+ + PF   GF +I
Sbjct: 348 YTSLGNIFGPALGGILFDLNIHYPFLFAGFVMI 380


>TCR3_ECOLI (P02981) Tetracycline resistance protein, class C
           (TETA(C))
          Length = 396

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 29/114 (25%), Positives = 54/114 (46%), Gaps = 5/114 (4%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G+   +  + + +  P+LG LSD  GR+P+LL ++      +A++A       +YA  ++
Sbjct: 46  GVLLALYALMQFLCAPVLGALSDRFGRRPVLLASLLGATIDYAIMATTPVLWILYAGRIV 105

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFL 170
              +     G+   ++ AY+AD+ +   RA  F  ++  F    V G V    L
Sbjct: 106 AGIT-----GATGAVAGAYIADITDGEDRARHFGLMSACFGVGMVAGPVAGGLL 154


>YMPB_CAEEL (Q7Z118) Hypothetical protein B0361.11 in chromosome III
          Length = 534

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 22/157 (14%)

Query: 61  TIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSF-AVLAWDQSEEFVYAYYVLRTF 119
           TI  I  ++ +P +  L+D +GRKP++   ++T I +F A +A   S  F   + +LR F
Sbjct: 151 TIFTIGAVIAVPFMSMLADRYGRKPII---VTTAILAFLANMAASFSPNFA-IFLILRAF 206

Query: 120 SYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNV---LARFLPEEY-- 174
               S   +   SVA   + ++E  RA    WIT +++ +  +G V   L   + +++  
Sbjct: 207 IGACSDSYLSVASVA-TCEYLSEKARA----WITVVYNVAWSLGMVWTLLVTLMTDDWRW 261

Query: 175 -IFVVSI------ALLTFCPVYMQFFLVETVTPAPKK 204
             F+VS+      AL  F P    + + +  T   KK
Sbjct: 262 RYFIVSLPGVYGFALWYFLPESPHWLITKNKTEKLKK 298


>OCTL_DROME (Q95R48) Organic cation transporter-like protein
          Length = 567

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 4/98 (4%)

Query: 73  LLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVLRTFSYIISQGSIFCIS 132
           + GQLSD++GRKP+L  ++   +  F VLA    E F Y +  L   +   +   +F ++
Sbjct: 147 VFGQLSDKYGRKPILFASLVIQVL-FGVLAGVAPEYFTYTFARLMVGA---TTSGVFLVA 202

Query: 133 VAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFL 170
                ++V   KR     ++   FS   ++  V A F+
Sbjct: 203 YVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFV 240


>NORA_STAAM (P21191) Quinolone resistance protein norA
          Length = 388

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 37/162 (22%), Positives = 72/162 (43%), Gaps = 22/162 (13%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLL---LITMSTTIFSFAVLAWDQSEEFVYAY 113
           GL      + +M++ P  G L+D+ G+K ++   LI  S + F FAV          ++ 
Sbjct: 41  GLLVAAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAV-------GHNFSV 93

Query: 114 YVLRTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPE- 172
            +L      +S G +       +AD+    ++A  F +++ + ++  ++G  +  F+ E 
Sbjct: 94  LMLSRVIGGMSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEV 153

Query: 173 ----EYIFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGF 210
                + F  ++ +L F    M   L+      PKK+  SGF
Sbjct: 154 SHRMPFYFAGALGILAF---IMSIVLIHD----PKKSTTSGF 188


>PMRA_LACLA (P58120) Multi-drug resistance efflux pump pmrA homolog
          Length = 405

 Score = 39.3 bits (90), Expect = 0.019
 Identities = 37/159 (23%), Positives = 72/159 (45%), Gaps = 13/159 (8%)

Query: 56  NGLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYV 115
           +GL  ++  +   +V P+ G+L+DEHGRK +++        +   +A+  +  ++    +
Sbjct: 52  SGLAFSLPALASGLVAPIWGRLADEHGRKVMMVRASIVMTLTMGGIAFAPNVWWLLGLRL 111

Query: 116 LRTF--SYIISQGSIFCISVAYVADVVNESKRA-AVFSWITGLFSASHV---VGNVLARF 169
           L  F   YI +       S A +A    + K   A+ +  T + S + +   +G +LA +
Sbjct: 112 LMGFFSGYIPN-------STAMIASQAPKDKSGYALGTLATAMVSGTLIGPSLGGLLAEW 164

Query: 170 LPEEYIFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVS 208
                +F++  ALL    +   FF+ E   P  K   +S
Sbjct: 165 FGMANVFLIVGALLALATLLTIFFVHENFEPIAKGEMLS 203



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 23/91 (25%), Positives = 46/91 (50%)

Query: 16  LLFPLSIHWIAEEMTVSVLVDVTTSALCPGGSTCPKVIYINGLQQTIVGIFKMVVLPLLG 75
           +LF L +     ++T   +    T  +    ++   +++I+GL  + VG+  M+    LG
Sbjct: 216 ILFGLLVTTFIIQITSQSIEPFVTLYIKTLTTSTNNLMFISGLIVSAVGLSAMLSSSFLG 275

Query: 76  QLSDEHGRKPLLLITMSTTIFSFAVLAWDQS 106
           +L D++G   L+LI +  T   +  +A+ QS
Sbjct: 276 RLGDKYGSHRLILIGLVFTFIIYLPMAFVQS 306


>Y450_BUCAP (Q8K999) Hypothetical transport protein BUsg450
          Length = 391

 Score = 38.9 bits (89), Expect = 0.025
 Identities = 38/172 (22%), Positives = 74/172 (42%), Gaps = 11/172 (6%)

Query: 54  YINGLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAY 113
           ++ GL   I G  ++V     G LSD  GRK +++  +        ++    S   ++  
Sbjct: 48  FLIGLAVGIYGATQIVFQIPFGILSDRFGRKQIIIFGLFIFFIGSLIVV---STNSIFGL 104

Query: 114 YVLRTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPEE 173
            + R    I   G+I  +S+A ++D++ +  R    S I   F+ S ++  V A  + E 
Sbjct: 105 IIGRA---IQGSGAISGVSMALLSDLIRKENRIKSISIIGVSFAVSFLISVVSAPIIAEN 161

Query: 174 Y----IFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKR 221
           +    IF +S A+ +   + + FFL+ +      KN       K +  +  +
Sbjct: 162 FGFFSIFWIS-AVFSIFSILIVFFLIPSSQNEILKNYKKNIYQKKIKFIFNK 212


>Y411_BUCBP (Q89AA9) Hypothetical transport protein bbp411
          Length = 394

 Score = 38.5 bits (88), Expect = 0.033
 Identities = 44/210 (20%), Positives = 92/210 (42%), Gaps = 23/210 (10%)

Query: 53  IYINGLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFA-VLAWDQSEEFVY 111
           I++ G+   I GIF+++     G LSD++G+K  L+I +    F    ++AW  S   ++
Sbjct: 47  IFLVGVAIGIYGIFQIIFQIPYGWLSDKYGQK--LIINIGLLCFLLGNIIAW--SSNSIW 102

Query: 112 AYYVLRTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLP 171
              + R        G+I  + +  ++++V    R  +   +   F  S  +  +L+  + 
Sbjct: 103 GIILGRGLQ---GSGAISSVCMTLLSELVLPHNRIKIMGLLGVSFGISFFLAVILSPIIV 159

Query: 172 EEY----IFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVD---VLHKRYKS 224
             +    +F+++  L  FC  +  F++  ++     KN V  F +++ +   +L  R   
Sbjct: 160 NMFGFYCLFLINSLLSIFCLFFGMFYIPASLL---NKNVVCNFRSEISNFFKILSNRVLC 216

Query: 225 MRNAAEILDNL-----IIAVQYYLKAVFGF 249
             N +  L +       I +   LK +F F
Sbjct: 217 QINLSVFLIHFFLMCNFIIIPVELKKIFEF 246


>ARAJ_ECOLI (P23910) Protein araJ precursor
          Length = 394

 Score = 37.7 bits (86), Expect = 0.056
 Identities = 40/216 (18%), Positives = 89/216 (40%), Gaps = 25/216 (11%)

Query: 68  MVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVLRTFSYIIS--- 124
           +V  P++   S  +  K +LL  ++  +   A+     S       Y++     ++S   
Sbjct: 52  VVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSS-------YLMLAIGRLVSGFP 104

Query: 125 QGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPEE----YIFVVSI 180
            G+ F +    ++ ++   K  A  + +    + ++++G  L  +L +E    Y F++ I
Sbjct: 105 HGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLL-I 163

Query: 181 ALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKRYKSMRNAAEILDNLIIA-- 238
           A+     +   +F V  +    K N    F       L      +  AA +  N  +   
Sbjct: 164 AVFNIAVMASVYFWVPDIRDEAKGNLREQF-----HFLRSPAPWLIFAATMFGNAGVFAW 218

Query: 239 ---VQYYLKAVFGFNKNQFSELLMMVGIGSIFSQMV 271
              V+ Y+  + GF++   + ++M+VG+G +   M+
Sbjct: 219 FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNML 254


>CIT1_ECOLI (P07661) Citrate-proton symporter (Citrate transporter)
           (Citrate carrier protein) (Citrate utilization
           determinant) (Citrate utilization protein A)
          Length = 431

 Score = 37.0 bits (84), Expect = 0.096
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 62  IVGIFKMVVLPLLGQLSDEHGRKPLLL-ITMSTTIFSFAVLAW-DQSEEFVYAYYVLRTF 119
           +VGI   + LP+ G +SD  GR+P+L+ IT+   + +  V+ W   + +F     VL  F
Sbjct: 279 LVGISNFIWLPIGGAISDRIGRRPVLMGITLLALVTTLPVMNWLTAAPDFTRMTLVLLWF 338

Query: 120 SYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSA 158
           S+    G      VA + +V+    R   FS    L +A
Sbjct: 339 SFFF--GMYNGAMVAALTEVMPVYVRTVGFSLAFSLATA 375


>YCEI_BACSU (O34691) Hypothetical metabolite transport protein yceI
          Length = 400

 Score = 36.6 bits (83), Expect = 0.13
 Identities = 70/350 (20%), Positives = 140/350 (40%), Gaps = 47/350 (13%)

Query: 73  LLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVLRTFSYIISQGSIFCIS 132
           L G L+D  GRK + +IT+        + A+  S   + A+ +LR F   +  G    ++
Sbjct: 65  LFGLLADRIGRKKVFIITLLCFSIGSGISAFVTS---LSAFLILR-FVIGMGLGGELPVA 120

Query: 133 VAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPEEYIFVVSIALLTFCPVYMQF 192
              V++ V   KR  V   +   ++   +   +++ F+   + +  ++ LLT    +   
Sbjct: 121 STLVSEAVVPEKRGRVIVLLESFWAVGWLAAALISYFVIPSFGWQAAL-LLTALTAFYAL 179

Query: 193 FLVETVTPAPKKNQVS----GFCTKVVDVLHKRYKSMRNAAEILDNLIIAVQY----YLK 244
           +L  ++  +PK   +S         V  V  ++Y        I+   ++   Y    +L 
Sbjct: 180 YLRTSLPDSPKYESLSAKKRSMWENVKSVWARQYIRPTVMLSIVWFCVVFSYYGMFLWLP 239

Query: 245 AVF---GFNKNQFSELLMMVGIGSI---FSQMVLLPILNPKVGEKVILSAALLASIAYAW 298
           +V    GF+  Q  E ++++ +  +   FS   L+     K G K IL   L+ +   A+
Sbjct: 240 SVMLLKGFSMIQSFEYVLLMTLAQLPGYFSAAWLI----EKAGRKWILVVYLIGTAGSAY 295

Query: 299 LYG--------LAWAPWVPYFS-ASFGIIY--------VLVKPSGKAQTFIAGAQSISDL 341
            +G        L     + +F+  ++G++Y          ++ +G   T   G   I  +
Sbjct: 296 FFGTADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYPTAIRATGSGTTAAFG--RIGGI 353

Query: 342 LSPIAMSPLTSWFLSSNAPFDCKGFSIICASVSMVAETENEKLKENLQDE 391
             P+ +  L +  +S +       FSI C ++ +         KE  Q E
Sbjct: 354 FGPLLVGTLAARHISFSVI-----FSIFCIAILLAVACILIMGKETKQTE 398


>BMR1_BACSU (P33449) Multidrug resistance protein 1
           (Multidrug-efflux transporter 1)
          Length = 389

 Score = 36.2 bits (82), Expect = 0.16
 Identities = 49/253 (19%), Positives = 102/253 (39%), Gaps = 18/253 (7%)

Query: 57  GLQQTIVGIFKMVVLPLLGQLSDEHGRKPLLLITMSTTIFSFAVLAWDQSEEFVYAYYVL 116
           G       I +++V P+ G+  D  GRK +++I +     S  +    ++ E ++   +L
Sbjct: 44  GYMVACFAITQLIVSPIAGRWVDRFGRKIMIVIGLLFFSVSEFLFGIGKTVEMLFISRML 103

Query: 117 RTFSYIISQGSIFCISVAYVADVVNESKRAAVFSWITGLFSASHVVGNVLARFLPE---- 172
              S       +     A++AD+     R     +++   S   ++G  +  FL E    
Sbjct: 104 GGISAPFIMPGV----TAFIADITTIKTRPKALGYMSAAISTGFIIGPGIGGFLAEVHSR 159

Query: 173 -EYIFVVSIALLTFCPVYMQFFLVETVTPAPKKNQVSGFCTKVVDVLHKRYKSMRNAAEI 231
             + F  + ALL      +    +      P+  ++ G  T    +    Y  +     +
Sbjct: 160 LPFFFAAAFALLA---AILSILTLREPERNPENQEIKGQKTGFKRIFAPMY-FIAFLIIL 215

Query: 232 LDNLIIAVQYYLKAVFGFNKNQF--SELLMMVGIGSI---FSQMVLLPILNPKVGEKVIL 286
           + +  +A    L A+F  +K  F  S++ +M+  G+I    +Q+VL        GE  ++
Sbjct: 216 ISSFGLASFESLFALFVDHKFGFTASDIAIMITGGAIVGAITQVVLFDRFTRWFGEIHLI 275

Query: 287 SAALLASIAYAWL 299
             +L+ S +  +L
Sbjct: 276 RYSLILSTSLVFL 288


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.324    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,963,265
Number of Sequences: 164201
Number of extensions: 1787107
Number of successful extensions: 7424
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 7387
Number of HSP's gapped (non-prelim): 66
length of query: 423
length of database: 59,974,054
effective HSP length: 113
effective length of query: 310
effective length of database: 41,419,341
effective search space: 12839995710
effective search space used: 12839995710
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)