BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0094b.3
         (337 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

IF2_LEPIN (Q8F7K1) Translation initiation factor IF-2                  44  6e-04
YTH1_MOUSE (P59326) YTH domain protein 1 (Dermatomyositis associ...    43  0.001
MYSD_CAEEL (P02567) Myosin heavy chain D (MHC D)                       42  0.002
MYH7_RABIT (P04461) Myosin heavy chain, cardiac muscle beta isof...    42  0.002
YTH1_HUMAN (Q9BYJ9) YTH domain protein 1 (Dermatomyositis associ...    42  0.002
MYH3_HUMAN (P11055) Myosin heavy chain, fast skeletal muscle, em...    41  0.004
EP15_HUMAN (P42566) Epidermal growth factor receptor substrate 1...    41  0.004
VRP1_YEAST (P37370) Verprolin                                          41  0.005
MYH7_MESAU (P13540) Myosin heavy chain, cardiac muscle beta isof...    41  0.005
MYH7_HUMAN (P12883) Myosin heavy chain, cardiac muscle beta isof...    41  0.005
TNK1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase...    40  0.006
SSP2_PLAYO (Q01443) Sporozoite surface protein 2 precursor             40  0.006
MYH6_HUMAN (P13533) Myosin heavy chain, cardiac muscle alpha iso...    40  0.006
CC02_CAEEL (P17656) Cuticle collagen 2 precursor                       40  0.006
MAD1_SCHPO (P87169) Spindle assembly checkpoint component mad1 (...    40  0.008
TPM3_HUMAN (P06753) Tropomyosin alpha 3 chain (Tropomyosin 3) (T...    40  0.011
STN3_CHICK (O93388) Stathmin 3 (SCG10-like protein) (Neuroplasti...    40  0.011
MYH7_PIG (P79293) Myosin heavy chain, cardiac muscle beta isofor...    40  0.011
MYH6_RAT (P02563) Myosin heavy chain, cardiac muscle alpha isofo...    40  0.011
MYH6_RABIT (P04460) Myosin heavy chain, cardiac muscle alpha iso...    40  0.011

>IF2_LEPIN (Q8F7K1) Translation initiation factor IF-2
          Length = 880

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 40/143 (27%), Positives = 56/143 (38%), Gaps = 34/143 (23%)

Query: 4   KPRVAEVGGKRQSSPVSACSPKRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLAS 63
           K  + +  G   S+P  A SPK+  V E DP + P        V P P+  DS   P+  
Sbjct: 39  KKLIIKKKGDDPSTPSPAASPKKETVAESDPSSKPP-------VMPLPLPDDSGQSPIVR 91

Query: 64  DHPSEVNASQTPDAP------RPVTLAEGQRSPSSIRPPIPSPVK------------VTL 105
             PS  + ++  ++P      RP    + ++   S  PP  SP +               
Sbjct: 92  PAPSSHSPAKREESPGKQDAGRPPRDKDTRQGGGSSYPPSRSPFQKEDSNIIVSRPIQRT 151

Query: 106 GPSAPNS---------PGVGGEG 119
           GPS PNS         PG GG G
Sbjct: 152 GPSRPNSGGGYQGNRGPGQGGGG 174


>YTH1_MOUSE (P59326) YTH domain protein 1 (Dermatomyositis
           associated with cancer putative autoantigen-1 homolog)
           (DACA-1 homolog)
          Length = 559

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 44/163 (26%), Positives = 67/163 (40%), Gaps = 13/163 (7%)

Query: 11  GGKRQSSPVS---ACSPKRSKVGEPDPQTTPLTGT-GGGFVAPDPVVTDSACDPLASDHP 66
           GG   + PVS   + +   SK  +P P+    +G   GG + P P+  +       +  P
Sbjct: 220 GGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGGALPPPPIKHNMDIGTWDNKGP 279

Query: 67  S-EVNASQTPDAPRPVTLAEGQRSPSSIRPPIPSPVKVTLGPSAPNSPG-VGGEGENLSA 124
           + + +A Q   +P+     +    P  ++PP P        P  P  P  V     N + 
Sbjct: 280 APKASAPQQTPSPQAAPQPQQVAQPLPVQPP-PLVQPQYQSPQQPLQPRWVAPRNRNAAF 338

Query: 125 AQPTGPSSSS------PPYPFSFLLSHPYLEKLKGAPSQNPQD 161
            Q  G +S S       P     + SHP LEKLK A S NP++
Sbjct: 339 GQSGGANSDSNSVGNAQPTSAPSVESHPVLEKLKAAHSYNPKE 381


>MYSD_CAEEL (P02567) Myosin heavy chain D (MHC D)
          Length = 1938

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 7/91 (7%)

Query: 194  RQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKLL 253
            +QEVE L++ ++A +  +A   +  AAK+ +I  L++E+  Q+E + +   +     KLL
Sbjct: 951  QQEVENLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEK----KLL 1006

Query: 254  ADYEAQAATLKEKIRSEAAHAAAKERVRGSL 284
             +   Q   L + +++E A  A   R+RG L
Sbjct: 1007 EENNRQ---LVDDLQAEEAKQAQANRLRGKL 1034



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 26/88 (29%), Positives = 47/88 (52%), Gaps = 2/88 (2%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L QE +ELQ  LD  E  + ++E  +     E+  +R E+E + +   E + + T K   
Sbjct: 1540 LEQEKDELQHALDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQE-KEEEFENTRKNHQ 1598

Query: 253  LADYEAQAATLKEKIRSEAAHAAAKERV 280
             A  E+  A+L+ + +S+A  A AK+++
Sbjct: 1599 RA-LESIQASLETEAKSKAELARAKKKL 1625



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 196  EVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKLLAD 255
            ++  L   LDA + + A  EK      KE+ D+  +++ + ++  E +       +L   
Sbjct: 1206 QISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQE-------RLAKQ 1258

Query: 256  YEAQAATLKEKIRSEAAHAAAKERVRGSL 284
            YE Q A L++K+  ++         +G L
Sbjct: 1259 YEIQVAELQQKVDEQSRQIGEYTSTKGRL 1287


>MYH7_RABIT (P04461) Myosin heavy chain, cardiac muscle beta isoform
           (MyHC-beta) (Beta isomyosin) (Fragment)
          Length = 736

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 193 LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
           L  E  EL+RD+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT K K 
Sbjct: 507 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKKKKA 562

Query: 253 LADYEAQA 260
           L +   QA
Sbjct: 563 LQEAHQQA 570



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 39/168 (23%), Positives = 64/168 (37%), Gaps = 22/168 (13%)

Query: 191 VGLRQEVEELQRDLDAKEITVASQEK----------FLAAKDKEIADLREELEGQNEALA 240
           V L QE  +LQ  + A++  +A  E+           L AK KE+ +  E+ E  N  L 
Sbjct: 442 VSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELT 501

Query: 241 EAQSDLTFKCK-----------LLADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAKAQ 289
             +  L  +C             LA  E +    + K+++     A  + +   L  K +
Sbjct: 502 AKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKKKK 561

Query: 290 VKHLHPTINLDPLGAFKRVTPAGLEGPQDPPEVADVDLGDAVEQEKKI 337
                    LD L A +       +      +  D DL  ++EQEKK+
Sbjct: 562 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD-DLEGSLEQEKKV 608


>YTH1_HUMAN (Q9BYJ9) YTH domain protein 1 (Dermatomyositis
           associated with cancer putative autoantigen-1) (DACA-1)
          Length = 559

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 45/164 (27%), Positives = 66/164 (39%), Gaps = 15/164 (9%)

Query: 11  GGKRQSSPVS---ACSPKRSKVGEPDPQTTPLTG-TGGGFVAPDPVVTDSACDPLASDHP 66
           GG   + PVS   + +   SK  +P P+    +G   GG + P P+  +   D    D+ 
Sbjct: 220 GGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNM--DIGTWDNK 277

Query: 67  SEVNASQTPD-APRPVTLAEGQR--SPSSIRPPIPSPVKVTLGPSAPNSPGVGGEGENLS 123
             V  +  P  AP P    + Q+   P   +PP  +  +       P +  V     N +
Sbjct: 278 GPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAA 337

Query: 124 AAQPTGPSSSS------PPYPFSFLLSHPYLEKLKGAPSQNPQD 161
             Q  G  S S       P     + SHP LEKLK A S NP++
Sbjct: 338 FGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKE 381


>MYH3_HUMAN (P11055) Myosin heavy chain, fast skeletal muscle,
            embryonic (Muscle embryonic myosin heavy chain) (SMHCE)
          Length = 1940

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 25/68 (36%), Positives = 39/68 (56%), Gaps = 4/68 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L  E  EL++D+D  E+T+A  EK   A + ++ +L EEL G +E +A+    LT + K 
Sbjct: 944  LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK----LTREKKA 999

Query: 253  LADYEAQA 260
            L +   QA
Sbjct: 1000 LQEAHQQA 1007



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNE---ALAEAQSDLTFK 249
            L+ E  EL R L+ KE  V+   +   A  ++  +L+ +LE +N+   ALA A       
Sbjct: 1281 LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHD 1340

Query: 250  CKLLAD-YEAQ 259
            C LL + YE +
Sbjct: 1341 CDLLREQYEEE 1351



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L+  +EEL+ +++A+  T A  EK       + +D   ELE  +E L EA    + + +L
Sbjct: 1112 LQARIEELEEEIEAERATRAKTEK-------QRSDYARELEELSERLEEAGGVTSTQIEL 1164

Query: 253  LADYEAQAATLKEKI 267
                EA+   L+  +
Sbjct: 1165 NKKREAEFLKLRRDL 1179


>EP15_HUMAN (P42566) Epidermal growth factor receptor substrate 15
           (Protein Eps15) (AF-1p protein)
          Length = 896

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 24/95 (25%), Positives = 51/95 (53%)

Query: 193 LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
           L  E+ +LQR+ +  E  +  +E  +  +  E+ DL++E++ +N  L + Q+      +L
Sbjct: 338 LNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQEL 397

Query: 253 LADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
           L + + Q A L+E+++      A + ++  SL A+
Sbjct: 398 LDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAE 432


>VRP1_YEAST (P37370) Verprolin
          Length = 817

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 15/120 (12%)

Query: 28  KVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLASDHP---------SEVNASQTPDAP 78
           K  E + ++ P+ G G    A     T S+  P  S  P          ++ A   P   
Sbjct: 45  KKAETNDRSAPIVGGGVVSSASGSSGTVSSKGPSMSAPPIPGMGAPQLGDILAGGIPKLK 104

Query: 79  RPVTLAEGQRSPSSIRPPIPSPVKVTLGPSAPNSPGVGGEGENLSAAQPTGPSSSSPPYP 138
                A  + SPS+  PPIP  V     P  PN+P       + + A P+ PSSS+PP P
Sbjct: 105 HINNNASTKPSPSASAPPIPGAVPSVAAPPIPNAP------LSPAPAVPSIPSSSAPPIP 158



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 35/147 (23%), Positives = 51/147 (33%), Gaps = 30/147 (20%)

Query: 5   PRVAEVGGKR--QSSPVSACSPKRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLA 62
           P +AE+  +R  + +     S K        P   PL  +        P +  S   PL 
Sbjct: 274 PFLAEINARRSERGAVEGVSSTKIQTENHKSPSQPPLPSSA-------PPIPTSHAPPLP 326

Query: 63  SDHPSEVNASQTPDAPRPVTLAEGQRSPSSIRPPIPS-------------PVKVTLGPSA 109
              P   +      AP+  T A     P+   PP+P+             PV  TL P  
Sbjct: 327 PTAPPPPSLPNVTSAPKKATSA-----PAPPPPPLPAAMSSASTNSVKATPVPPTLAPPL 381

Query: 110 PNSPGVGGEGENLSAAQPTGPSSSSPP 136
           PN+  V     N +++ P  P    PP
Sbjct: 382 PNTTSV---PPNKASSMPAPPPPPPPP 405



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 34/148 (22%), Positives = 48/148 (31%), Gaps = 18/148 (12%)

Query: 5   PRVAEVGGKRQSSPVSACSPKRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLASD 64
           P V     K  S+P     P  + +      +   T        P P  T      +  +
Sbjct: 336 PNVTSAPKKATSAPAPPPPPLPAAMSSASTNSVKATPVPPTLAPPLPNTTS-----VPPN 390

Query: 65  HPSEVNASQTPDAPRPVTLAEGQR-SPSSIR----PPIPSPVKVTLGPSAP--------N 111
             S + A   P  P P   +     S SSI     PP P P   T  PSAP        N
Sbjct: 391 KASSMPAPPPPPPPPPGAFSTSSALSASSIPLAPLPPPPPPSVATSVPSAPPPPPTLTTN 450

Query: 112 SPGVGGEGENLSAAQPTGPSSSSPPYPF 139
            P    +   +S++  +   +   P PF
Sbjct: 451 KPSASSKQSKISSSSSSSAVTPGGPLPF 478


>MYH7_MESAU (P13540) Myosin heavy chain, cardiac muscle beta isoform
            (MyHC-beta)
          Length = 1934

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 25/68 (36%), Positives = 39/68 (56%), Gaps = 4/68 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L  E  EL+RD+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 942  LEDECSELKRDIDDLELTLAKVEKDKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 997

Query: 253  LADYEAQA 260
            L +   QA
Sbjct: 998  LQEAHQQA 1005



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 11/99 (11%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTF 248
            L+  +EEL+ +L+A+    A  EK  +       DL  ELE  +E L EA       +  
Sbjct: 1110 LQARIEELEEELEAERTARAKVEKLRS-------DLSRELEEISERLEEAGGATSVQIEM 1162

Query: 249  KCKLLADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
              K  A+++     L+E      A AAA  +     +A+
Sbjct: 1163 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1201



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 26/95 (27%), Positives = 44/95 (45%), Gaps = 6/95 (6%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEA---LAEAQSDLTFK 249
            L+ E  EL R LD KE  ++   +      +++ DL+ +LE + +A   LA A       
Sbjct: 1279 LQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNTLAHALQSARHD 1338

Query: 250  CKLLADY---EAQAATLKEKIRSEAAHAAAKERVR 281
            C LL +    E +A    + + S+A    A+ R +
Sbjct: 1339 CDLLREQYEEETEAKAELQCVLSKANSEVAQWRTK 1373


>MYH7_HUMAN (P12883) Myosin heavy chain, cardiac muscle beta isoform
            (MyHC-beta)
          Length = 1935

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 25/68 (36%), Positives = 39/68 (56%), Gaps = 4/68 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L  E  EL+RD+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 943  LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 998

Query: 253  LADYEAQA 260
            L +   QA
Sbjct: 999  LQEAHQQA 1006



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 26/95 (27%), Positives = 44/95 (45%), Gaps = 6/95 (6%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQ---NEALAEAQSDLTFK 249
            L+ E  EL R LD KE  ++   +      +++ DL+ +LE +     ALA A       
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339

Query: 250  CKLLADY---EAQAATLKEKIRSEAAHAAAKERVR 281
            C LL +    E +A    +++ S+A    A+ R +
Sbjct: 1340 CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTF 248
            L+++++ELQ  ++  E  + S+    A  +K  +DL  ELE  +E L EA       +  
Sbjct: 1104 LQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1163

Query: 249  KCKLLADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
              K  A+++     L+E      A AAA  +     +A+
Sbjct: 1164 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202


>TNK1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase I)
           (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose
           polymerase)
          Length = 1327

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 38/129 (29%), Positives = 47/129 (35%), Gaps = 16/129 (12%)

Query: 32  PDPQTTPLT-GTGGGFVAPDPVVTDSACDPLASDH-----PSEVNASQTPDAPRPVTLAE 85
           P P   PL+ G   G     P  T S   P AS       P    +   PD PR     +
Sbjct: 28  PPPPPPPLSPGLAPGTTPASP--TASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVD 85

Query: 86  GQRSPSSIR--------PPIPSPVKVTLGPSAPNSPGVGGEGENLSAAQPTGPSSSSPPY 137
           G    S+          P +P+    +    APN  G G      S++ PT  SSSSP  
Sbjct: 86  GTSCCSTTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSS 145

Query: 138 PFSFLLSHP 146
           P S L   P
Sbjct: 146 PGSSLAESP 154


>SSP2_PLAYO (Q01443) Sporozoite surface protein 2 precursor
          Length = 827

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/134 (23%), Positives = 47/134 (34%), Gaps = 3/134 (2%)

Query: 4   KPRVAEVGGKRQSSPVSACSPKRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLAS 63
           KP   E     + +P    +P +    EP     P          P+P    +  +P   
Sbjct: 414 KPNPNEPSNPNKPNPNEPSNPNKPNPNEPSNPNKPNPNEPSNPNKPNPNEPLNPNEPSNP 473

Query: 64  DHPSEVNASQTPDAPRPVTLAEGQRSPSSIRPPI-PSPVKVTLGPSAPNSPGVGGEGENL 122
           + PS  NA   P+ P           PS+   P  P+       PS PN P      E L
Sbjct: 474 NEPSNPNAPSNPNEPSNPNEPSNPNEPSNPNEPSNPNEPSNPKKPSNPNEP--SNPNEPL 531

Query: 123 SAAQPTGPSSSSPP 136
           +  +P+ P+  S P
Sbjct: 532 NPNEPSNPNEPSNP 545



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 34/152 (22%), Positives = 61/152 (39%), Gaps = 19/152 (12%)

Query: 16  SSPVSACSPKRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLASDHPSEVNASQTP 75
           S+P    +PK  K   P+  + P           +P+  +   +P    +P+E +  + P
Sbjct: 507 SNPNEPSNPK--KPSNPNEPSNP----------NEPLNPNEPSNPNEPSNPNEPSNPEEP 554

Query: 76  DAPRPVTLAEGQRSPSSIRPPIPSPVKVTLGPSAPNSPGVGGEGENLSAAQPTGPSSSSP 135
             P+  +      +P    P  PS  K    P  P +P      E L+  +P+ P  S+P
Sbjct: 555 SNPKEPSNPNEPSNPEEPNPEEPSNPKEPSNPEEPINP------EELNPKEPSNPEESNP 608

Query: 136 PYPFSFLLSHPYLEKLKGAPSQNPQDVAQEAV 167
             P +   S+P  E +    ++NP  +  E +
Sbjct: 609 KEPINPEESNP-KEPINPEDNENPLIIQDEPI 639



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 59  DPLASDHPSEVNASQTPDAPRPVTLAEGQRSPSSIRPPIPSPVKVTLG-PSAPNSPGVGG 117
           +P   ++P+  N    P+ P P      +R+P+  +P  P+P K     PS PN P    
Sbjct: 371 NPNNPNNPNNPNDPSNPNNPNPKKRNPKRRNPNKPKPNKPNPNKPNPNEPSNPNKPN-PN 429

Query: 118 EGENLSAAQPTGPSSSSPPYP 138
           E  N +   P  PS+ + P P
Sbjct: 430 EPSNPNKPNPNEPSNPNKPNP 450


>MYH6_HUMAN (P13533) Myosin heavy chain, cardiac muscle alpha isoform
            (MyHC-alpha)
          Length = 1939

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 26/89 (29%), Positives = 49/89 (54%), Gaps = 5/89 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L  E  EL++D+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 945  LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 1000

Query: 253  LADYEAQAATLKEKIRSEAAHAAAKERVR 281
            L +   QA     ++  +  ++ +K +V+
Sbjct: 1001 LQEAHQQALD-DLQVEEDKVNSLSKSKVK 1028



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 6/95 (6%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNE---ALAEAQSDLTFK 249
            L+ E  EL R L+ KE  ++   +   +  +++ DL+ +LE + +   ALA A       
Sbjct: 1282 LQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHD 1341

Query: 250  CKLLADY---EAQAATLKEKIRSEAAHAAAKERVR 281
            C LL +    E +A    +++ S+A    A+ R +
Sbjct: 1342 CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1376



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 26/95 (27%), Positives = 41/95 (42%), Gaps = 11/95 (11%)

Query: 197  VEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTFKCKL 252
            +EEL+ +L+A+    A  EK  +       DL  ELE  +E L EA       +    K 
Sbjct: 1117 IEELEEELEAERTARAKVEKLRS-------DLSRELEEISERLEEAGGATSVQIEMNKKR 1169

Query: 253  LADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
             A+++     L+E      A AAA  +     +A+
Sbjct: 1170 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1204


>CC02_CAEEL (P17656) Cuticle collagen 2 precursor
          Length = 301

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 33/115 (28%), Positives = 37/115 (31%), Gaps = 2/115 (1%)

Query: 25  KRSKVGEPDPQTTPLTGTGGGFVAPDPVVTDSACDPLASDHPSEVNASQTPDAPRPVTLA 84
           K  K G+P     P    G G  AP   VT   C P     P     +  P  P P    
Sbjct: 115 KPGKPGKPGAPGAP-GNPGKGASAPCEPVTQPPCQPCPGGPPGPAGPAGPPGPPGPDGNP 173

Query: 85  EGQRSPSSIRPP-IPSPVKVTLGPSAPNSPGVGGEGENLSAAQPTGPSSSSPPYP 138
                PS   P   P P        AP +PG  GE        P  P  + PP P
Sbjct: 174 GSPAGPSGPGPAGPPGPAGPAGNDGAPGAPGGPGEPGASEQGGPGEPGPAGPPGP 228


>MAD1_SCHPO (P87169) Spindle assembly checkpoint component mad1
           (Mitotic arrest deficient protein 1)
          Length = 689

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 35/139 (25%), Positives = 72/139 (51%), Gaps = 27/139 (19%)

Query: 194 RQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQ---------- 243
           ++E+EE++ + +A ++ +    + L AK KEIA+L+ ++E  ++AL+E            
Sbjct: 118 QKEIEEVRNEKEATQVKI---HELLDAKWKEIAELKTQIEKNDQALSEKNHEVMVSNQAL 174

Query: 244 ----SDLTFKCKLLADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAKAQ----VKHLHP 295
               ++LT   KL AD   Q  T  +++      AAA+++++   +   Q    +K +  
Sbjct: 175 QMKDTNLTNLEKLFADSREQLETKCKEL------AAAEQQLQELSVHNQQLEESIKQVSS 228

Query: 296 TINLDPLGAFKRVTPAGLE 314
           +I L+ + A +R+  + LE
Sbjct: 229 SIELEKINAEQRLQISELE 247



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 24/78 (30%), Positives = 41/78 (51%), Gaps = 10/78 (12%)

Query: 199 ELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQN---EALAEAQSDLTFKCKLLAD 255
           EL++    + + ++  EK  AA+++ I    E+L   N   E L E ++DL  K     +
Sbjct: 231 ELEKINAEQRLQISELEKLKAAQEERI----EKLSSNNRNVEILKEEKNDLESKLYRFEE 286

Query: 256 YEAQAATLK---EKIRSE 270
           Y  + ATL+   EKI++E
Sbjct: 287 YRDKVATLELENEKIQTE 304


>TPM3_HUMAN (P06753) Tropomyosin alpha 3 chain (Tropomyosin 3)
           (Tropomyosin gamma) (hTM5)
          Length = 284

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 6/90 (6%)

Query: 196 EVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKLLAD 255
           E E+ Q +  +K++     E  LAA  K++    +EL+  +EAL +AQ  L    K  AD
Sbjct: 26  EAEQKQAEERSKQL-----EDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAAD 80

Query: 256 YEAQAATLKEKIR-SEAAHAAAKERVRGSL 284
            EA+ A+L  +I+  E     A+ER+  +L
Sbjct: 81  AEAEVASLNRRIQLVEEELDRAQERLATAL 110


>STN3_CHICK (O93388) Stathmin 3 (SCG10-like protein)
           (Neuroplasticin-2)
          Length = 180

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 197 VEELQRDLDAKEITVASQE----KFLAAK-DKEIADLREELEGQNEALAEAQSDLTFKCK 251
           +EELQR L+A E    +QE    K LA K + E   L + LE  N     A+  L +K +
Sbjct: 82  LEELQRRLEAAEERRKTQEAQVLKQLAEKREHEREVLHKALEENNNFSRLAEEKLNYKME 141

Query: 252 LLADY-EAQAATLKEKIRSEAAHAAAKER 279
           L  +  EA  A L+E++R +  HAA   R
Sbjct: 142 LSREIREAHLAALRERLREKELHAAEVRR 170


>MYH7_PIG (P79293) Myosin heavy chain, cardiac muscle beta isoform
            (MyHC-beta)
          Length = 1935

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            +  E  EL+RD+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 943  VEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 998

Query: 253  LADYEAQA 260
            L +   QA
Sbjct: 999  LQEAHQQA 1006



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 11/99 (11%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTF 248
            L+  +EEL+ +L+A+    A  EK  +       DL  ELE  +E L EA       +  
Sbjct: 1111 LQARIEELEEELEAERTARAKVEKLRS-------DLSRELEEISERLEEAGGATSVQIEM 1163

Query: 249  KCKLLADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
              K  A+++     L+E      A AAA  +     +A+
Sbjct: 1164 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 27/95 (28%), Positives = 44/95 (45%), Gaps = 6/95 (6%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQ---NEALAEAQSDLTFK 249
            L+ E  EL R LD KE  ++   +      +++ DL+ +LE +     ALA A       
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHA 1339

Query: 250  CKLLAD-YEAQAATLKE--KIRSEAAHAAAKERVR 281
              LL + YE +  T  E  ++ S+A    A+ R +
Sbjct: 1340 ADLLREQYEEETETKAELQRVLSKANSEVAQWRTK 1374


>MYH6_RAT (P02563) Myosin heavy chain, cardiac muscle alpha isoform
            (MyHC-alpha)
          Length = 1938

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
            L  E  EL++D+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 944  LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 999

Query: 253  LADYEAQA 260
            L +   QA
Sbjct: 1000 LQEAHQQA 1007



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 193  LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNE---ALAEAQSDLTFK 249
            L+ E  EL R L+ KE  +    +   +  +++ DL+ +LE + +   ALA A       
Sbjct: 1281 LQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHD 1340

Query: 250  CKLLADY---EAQAATLKEKIRSEAAHAAAKERVR 281
            C LL +    E +A    +++ S+A    A+ R +
Sbjct: 1341 CDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTK 1375



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 26/95 (27%), Positives = 41/95 (42%), Gaps = 11/95 (11%)

Query: 197  VEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTFKCKL 252
            +EEL+ +L+A+    A  EK  +       DL  ELE  +E L EA       +    K 
Sbjct: 1116 IEELEEELEAERTARAKVEKLRS-------DLTRELEEISERLEEAGGATSVQIEMNKKR 1168

Query: 253  LADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
             A+++     L+E      A AAA  +     +A+
Sbjct: 1169 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1203


>MYH6_RABIT (P04460) Myosin heavy chain, cardiac muscle alpha
           isoform (MyHC-alpha) (Alpha isomyosin) (Fragment)
          Length = 465

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 193 LRQEVEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEAQSDLTFKCKL 252
           L  E  EL++D+D  E+T+A  EK   A + ++ +L EE+ G +E +A+    LT + K 
Sbjct: 140 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKA 195

Query: 253 LADYEAQA 260
           L +   QA
Sbjct: 196 LQEAHQQA 203



 Score = 30.4 bits (67), Expect = 6.6
 Identities = 26/95 (27%), Positives = 41/95 (42%), Gaps = 11/95 (11%)

Query: 197 VEELQRDLDAKEITVASQEKFLAAKDKEIADLREELEGQNEALAEA----QSDLTFKCKL 252
           +EEL+ +L+A+    A  EK  +       DL  ELE  +E L EA       +    K 
Sbjct: 312 IEELEEELEAERTARAKVEKLRS-------DLSRELEEISERLEEAGGATSVQIEMNKKR 364

Query: 253 LADYEAQAATLKEKIRSEAAHAAAKERVRGSLIAK 287
            A+++     L+E      A A+A  R     +A+
Sbjct: 365 EAEFQKMRRDLEEATLQHEATASALRRKHADSVAE 399


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.310    0.129    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,893,291
Number of Sequences: 164201
Number of extensions: 2043056
Number of successful extensions: 10442
Number of sequences better than 10.0: 659
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 525
Number of HSP's that attempted gapping in prelim test: 8714
Number of HSP's gapped (non-prelim): 1857
length of query: 337
length of database: 59,974,054
effective HSP length: 111
effective length of query: 226
effective length of database: 41,747,743
effective search space: 9434989918
effective search space used: 9434989918
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)