BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0087.21
(1215 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z291_HUMAN (Q9BY12) Zinc finger protein 291 140 2e-32
INCE_HUMAN (Q9NQS7) Inner centromere protein 85 1e-15
TRHY_RABIT (P37709) Trichohyalin 79 1e-13
TRHY_HUMAN (Q07283) Trichohyalin 78 2e-13
INCE_MOUSE (Q9WU62) Inner centromere protein 77 3e-13
PLE1_CRIGR (Q9JI55) Plectin 1 (PLTN) (PCN) (300-kDa intermediate... 75 8e-13
PLE1_RAT (P30427) Plectin 1 (PLTN) (PCN) 74 2e-12
INCE_CHICK (P53352) Inner centromere protein 74 2e-12
YAFA_SCHPO (Q09863) Hypothetical protein C29E6.10c in chromosome I 72 1e-11
TRHY_SHEEP (P22793) Trichohyalin 72 1e-11
PLE1_HUMAN (Q15149) Plectin 1 (PLTN) (PCN) (Hemidesmosomal prote... 69 6e-11
MYH9_HUMAN (P35579) Myosin heavy chain, nonmuscle type A (Cellul... 69 8e-11
IF3A_MAIZE (Q9XHR2) Eukaryotic translation initiation factor 3 s... 67 2e-10
AZI1_MOUSE (Q62036) 5-azacytidine induced protein 1 (Pre-acrosom... 67 3e-10
SPEN_DROME (Q8SX83) Split ends protein 67 4e-10
CALD_CHICK (P12957) Caldesmon (CDM) 66 5e-10
MST2_DROHY (Q08696) Axoneme-associated protein mst101(2) 66 7e-10
YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome ... 65 9e-10
IF3A_TOBAC (Q40554) Eukaryotic translation initiation factor 3 s... 64 2e-09
MYH9_RAT (Q62812) Myosin heavy chain, nonmuscle type A (Cellular... 64 2e-09
>Z291_HUMAN (Q9BY12) Zinc finger protein 291
Length = 1399
Score = 140 bits (354), Expect = 2e-32
Identities = 125/452 (27%), Positives = 224/452 (48%), Gaps = 41/452 (9%)
Query: 36 HAMSKCLTSESVGNMNGTHNAKNSRTKSRKHIGSSDANQGNLNVKKHNI---EGTKPCDA 92
H+ L ++ ++ + KNS + ++ +S+ + +++ + ++ GT P
Sbjct: 333 HSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYVRTSEISAVHIDTECVSVMLQAGTPP--- 389
Query: 93 IRVQKGYIPPESL-LTSEVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEV 151
++V + P E + +E+D + + NS A AK K L AD+L ++A
Sbjct: 390 LQVNEEKFPAEKARIENEMDPS---DISNSMAEVLAK-KEEL---ADRLEKANEEAIASA 442
Query: 152 INEKNPRSTDNLRRQMQLPEKDK--------EKRSTSLGK-SMNAWKEKRNWEDILSSPF 202
I E+ + L R+++ E + S S+G S++ +W D+L+ +
Sbjct: 443 IAEE-----EQLTREIEAEENNDINIETDNDSDFSASMGSGSVSFCGMSMDWNDVLAD-Y 496
Query: 203 RVSSRMSYSPSLGRKSAERVRT-------LHDKLMSPEKKKKTTSDLKKEAEEKHARALR 255
+ S G E +H+KL SP +K+ T ++ KK+ EEK +A +
Sbjct: 497 EARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKR-TIAESKKKHEEKQMKAQQ 555
Query: 256 IRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRA 315
+R +L E+ KLQ+ ++ V +W + R M + +E + E L + K+A
Sbjct: 556 LREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKA 615
Query: 316 GDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLER 375
+E +KVNE+ FI +L +NK+ + KL E R E + + +Q+E AR+EAV ER
Sbjct: 616 QEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQER 675
Query: 376 RKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEER----AKAQQ 431
++ +EAE+ R+ E+ K++E + R E++R+ ARE A E+ R +EER AQQ
Sbjct: 676 KRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQ 735
Query: 432 EEAELLAQKLAERLNESEQRRKIYLEQIRERA 463
E E L +K+ + +ES +R +EQ +E+A
Sbjct: 736 EAMEELQKKIQLKHDESIRRHMEQIEQRKEKA 767
Score = 102 bits (253), Expect = 8e-21
Identities = 62/193 (32%), Positives = 100/193 (51%), Gaps = 18/193 (9%)
Query: 907 NLAQPVVFLLSALSETGLVSLPSLLTAVLLQAN--NRSSSEP----------VATGVLKV 954
N Q L +AL T L + +L VL + S++ P VA L+
Sbjct: 1162 NNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPKENYTQNTIQVAIQSLRF 1221
Query: 955 LNNVALLDLVFLQRMLARPDLKMEIFHLMSFMLSHCASRWKTPNDQVGSLMLESLSLLGH 1014
N+ A L L Q ++ L + H+ S +L HC+ SL+ E + +G+
Sbjct: 1222 FNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQV------SCESLLHEVIVCVGY 1275
Query: 1015 FALFHPGNQAVLRWGKSPTILHKVCDLPFIFFSDPELMPILAGTLVAACYGCEQNKFVVQ 1074
F + HP NQ +++ G+ PT+L K+C LPF +FSDP L+ +L +L+AACY QNK +++
Sbjct: 1276 FTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAACYNNHQNKIILE 1335
Query: 1075 QELSVDMLLSLLR 1087
QE+S +L + ++
Sbjct: 1336 QEMSCVLLATFIQ 1348
>INCE_HUMAN (Q9NQS7) Inner centromere protein
Length = 919
Score = 84.7 bits (208), Expect = 1e-15
Identities = 83/353 (23%), Positives = 162/353 (45%), Gaps = 32/353 (9%)
Query: 160 TDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSA 219
TD + P+ + KRS ++++ E+++ ED P R S+ SP K
Sbjct: 434 TDQADGPREPPQSARRKRSYK--QAVSELDEEQHLEDEELQPPR--SKTPSSPCPASKVV 489
Query: 220 ERVRTL------HDKLMSPEKKK--------KTTSDLKKEAEEKHARALR-IRSELETER 264
+RT + LM+P K + L+ + +EK + L +R + E E+
Sbjct: 490 RPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQ 549
Query: 265 VQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNE 324
+++ + K R+ E R +LR+ + AR +R E E Q+ ++ K +
Sbjct: 550 LRRQKVEEDKRRRLEEVKLKREERLRKVLQAR-ERVEQMKEEKKKQIEQKFAQIDEKTEK 608
Query: 325 VRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSK---QKEDLAREEAVLERRKLIEA 381
+ E+ KK +K+ E RR ++ + + Q+E+ R + +L+++K E
Sbjct: 609 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEDARRLRWLQQEEEERRHQELLQKKKEEEQ 668
Query: 382 EKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
E+L++ AE +R E+ + R E+ + RE EQ RR++ER + +++ AE ++
Sbjct: 669 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERREQERQLAEQERRRE 728
Query: 442 AER------LNESEQRRKIYLEQIR---ERANLRDQSSPLLRRSLNKDGQGRS 485
ER L E E+ ++ EQ++ E +++ L R L ++ + ++
Sbjct: 729 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 781
Score = 60.8 bits (146), Expect = 2e-08
Identities = 89/414 (21%), Positives = 170/414 (40%), Gaps = 57/414 (13%)
Query: 45 ESVGNMNGTHNAKN--SRTKSRKHIGSSDA--NQGNLNVKKHNIEGTK-PCDAIRVQKGY 99
E+ GN + HN + T + K SS + G K +G + P + R ++ Y
Sbjct: 394 ENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSY 453
Query: 100 IPPESLLTSEVDL---------AKLPSLENSSALATAKVKTHLGS-GADKLLSLKDKAPT 149
S L E L +K PS ++ ++T L + +++L AP
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPR 513
Query: 150 EVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMS 209
V+ R+T +++ K+KE++ + + K E + R
Sbjct: 514 SVMKSFIKRNTP-----LRMDPKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRR 562
Query: 210 YSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHA----RALRIRSELETERV 265
+ K ER+R + L + E+ ++ + KK+ E+K A + + + E E
Sbjct: 563 LE-EVKLKREERLRKV---LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 618
Query: 266 QKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEV 325
K + ++K+ V E + R + + + E RH+ L + + + K E
Sbjct: 619 AKKKAAAKKMEEV-EARRKQEEDARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA 677
Query: 326 RFITSLNEENKKLILR--QKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKL----- 378
+ + E+ ++ R Q+ E R E+ + + +Q+ LA +E E+ +L
Sbjct: 678 KRLAEQREQERREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 737
Query: 379 ---------IEAEKLQRLAEMQRKKEEAQ------IRREEERKASSAAREARAI 417
++ E+LQR E ++KKEE Q ++ E+E+KA AA ++A+
Sbjct: 738 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 791
>TRHY_RABIT (P37709) Trichohyalin
Length = 1407
Score = 78.6 bits (192), Expect = 1e-13
Identities = 81/336 (24%), Positives = 149/336 (44%), Gaps = 28/336 (8%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
E+ D RRQ Q E++ E+++ + W+ + E R R+S PS
Sbjct: 399 EEQSLRQDQERRQRQERERELEEQA----RRQQQWQAEEESE-------RRRQRLSARPS 447
Query: 214 LGRKS--AERVRTLHDKLMSPEKKKKTTSDLKKEAEEKH-------ARALRIRSELETER 264
L + AE + + E++++ + EE+ A+ L+ + +R
Sbjct: 448 LRERQLRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDR 507
Query: 265 VQKLQRTSQKLNRVSEWHAVRHL-KLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVN 323
++ ++ Q+ + W + R +YA+ + E E Q KR + +
Sbjct: 508 ERRRRQQEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYR 567
Query: 324 EVRFITSLNEENKKLILRQKLHGS--ELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEA 381
E + +E ++ R++ + ELR+ E+L+ K +++E L +E ER + E
Sbjct: 568 EEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQEREE-ERLRRQER 626
Query: 382 EKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
E+ R E ++EE ++R+E ERK + R EQ R+E K ++EE +LL ++
Sbjct: 627 ERKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQELRQERERKLREEE-QLLQERE 685
Query: 442 AERLNESEQRRKIYLEQ---IRERANLRDQSSPLLR 474
ERL E+ RK+ E+ +E LR + LR
Sbjct: 686 EERLRRQERARKLREEEQLLRQEEQELRQERERKLR 721
Score = 74.3 bits (181), Expect = 2e-12
Identities = 84/337 (24%), Positives = 151/337 (43%), Gaps = 38/337 (11%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLG---RKSA 219
LRR+ Q ++++++ + + +E+R FR R L R+
Sbjct: 989 LRREEQELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQFRQER 1048
Query: 220 ERVRTLHDKLMSPEKKK---KTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLN 276
+R L +++ +++K + D K EE+ R +L ER +K + Q L
Sbjct: 1049 DRKFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRRERDRKFREEEQLLQ 1108
Query: 277 RVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK 336
E +LR AR R E + Q+ ++ D + E L +E++
Sbjct: 1109 EREEE------RLRRQERARKLREEEQLLRREEQLLRQERDRKFREEE-----QLLQESE 1157
Query: 337 KLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEE 396
+ LR++ +LR E Q+++ +++E L R+E RKL E E+L R E + ++E
Sbjct: 1158 EERLRRQERERKLREEE--QLLQEREEERLRRQE---RARKLREEEQLLRQEEQELRQER 1212
Query: 397 AQ--------IRREEERKASSAAREARAIEQLRRKE------ERAKAQQEEAELLAQKLA 442
A+ +R+EE+ R+ R EQL R+E ER + +EE +LL ++
Sbjct: 1213 ARKLREEEQLLRQEEQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREE 1272
Query: 443 ERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNK 479
ERL E+ RK+ E+ E+ +Q LR+ ++
Sbjct: 1273 ERLRRQERARKLREEE--EQLLFEEQEEQRLRQERDR 1307
Score = 74.3 bits (181), Expect = 2e-12
Identities = 65/272 (23%), Positives = 125/272 (45%), Gaps = 15/272 (5%)
Query: 214 LGRKSAERVRTLH-DKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTS 272
L + ER+R D+ E+++ +L+++ ++ R R+ ++ E+ +K R
Sbjct: 1011 LQEREEERLRRQERDRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQ 1070
Query: 273 QKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLN 332
++ + E R + RE R + + R E L Q E ++ L
Sbjct: 1071 ERDRKFREEEQQRRRQEREQQLRRERDRKFREEEQLLQER-----EEERLRRQERARKLR 1125
Query: 333 EENKKLILRQKLHGSELRRA--EKLQVIKSKQKEDLAREEA---VLERRKLIEAEKLQRL 387
EE + L ++L E R E+ Q+++ ++E L R+E + E +L++ + +RL
Sbjct: 1126 EEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKLREEEQLLQEREEERL 1185
Query: 388 AEMQR----KKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAE 443
+R ++EE +R+EE+ AR+ R EQL R+EE+ Q+ + + ++
Sbjct: 1186 RRQERARKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKFREEEQLL 1245
Query: 444 RLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
R E E RR+ + E L+++ LRR
Sbjct: 1246 RREEQELRRERDRKFREEEQLLQEREEERLRR 1277
Score = 71.2 bits (173), Expect = 2e-11
Identities = 89/330 (26%), Positives = 142/330 (42%), Gaps = 52/330 (15%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERV 222
LR + QL ++ +E+R + +E+ FR ++ L + ER+
Sbjct: 742 LREEEQLLQESEEERLRRQEREQQLRRER-------DRKFREEEQL-----LQEREEERL 789
Query: 223 RTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWH 282
R E+K + L +E EE+ R +L E +R ++L R
Sbjct: 790 RR-----QERERKLREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQE--- 841
Query: 283 AVRHLKLREG-MYARHQRSESRHEAF--LAQVAKRAGDESSKVNEVRFITSLNEENKKLI 339
R KLRE R + E R E L + + E ++ + R L EE + +
Sbjct: 842 --RERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERD-RKLREEEQ--L 896
Query: 340 LRQKLHGSELRRAEKL----QVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKE 395
LRQ+ R KL Q+++ ++E L R+E RKL E E+L R E + ++E
Sbjct: 897 LRQEEQELRQERDRKLREEEQLLQESEEERLRRQE---RERKLREEEQLLRREEQELRRE 953
Query: 396 EAQIRREEER----------KASSAAREARAIEQLRRKEERAKAQQ------EEAELLAQ 439
A+ REEE+ + AR+ R EQL R+EE+ Q+ EE +LL +
Sbjct: 954 RARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREEQELRQERDRKFREEEQLLQE 1013
Query: 440 KLAERLNESEQRRKIYLEQIR-ERANLRDQ 468
+ ERL E+ RK E+ + R L +Q
Sbjct: 1014 REEERLRRQERDRKFREEERQLRRQELEEQ 1043
Score = 70.9 bits (172), Expect = 2e-11
Identities = 77/345 (22%), Positives = 148/345 (42%), Gaps = 21/345 (6%)
Query: 138 DKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDI 197
++L K + +++ E+ R+ +L E+++ R ++ R E +
Sbjct: 599 EQLRDRKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLREEEQL 658
Query: 198 LSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIR 257
L L ++ ++R L E+++ + ++ E+ +
Sbjct: 659 LRRE---------EQELRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEE 709
Query: 258 SELETERVQKLQRTSQKLNRVSEW-HAVRHLKLREGMYARHQRSESR-----HEAFLAQV 311
EL ER +KL+ Q L R + R KLRE + E R E L +
Sbjct: 710 QELRQERERKLREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRE 769
Query: 312 AKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEA 371
R E ++ + R L + ++ LR++ + R E+L+ + +++ L EE
Sbjct: 770 RDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLR--RQERERKLREEEQ 827
Query: 372 VLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKA-SSAAREARAIEQLRRKEERAKAQ 430
+L+ R E E+L+R ++ +EE Q+ R+EE++ AR+ R EQL R+EE+ Q
Sbjct: 828 LLQER---EEERLRRQERERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQ 884
Query: 431 QEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
+ + +L ++ R E E R++ + E L++ LRR
Sbjct: 885 ERDRKLREEEQLLRQEEQELRQERDRKLREEEQLLQESEEERLRR 929
Score = 70.5 bits (171), Expect = 3e-11
Identities = 69/259 (26%), Positives = 122/259 (46%), Gaps = 32/259 (12%)
Query: 220 ERVRTLHDK---LMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLN 276
ER R L ++ L E+++ + +++ E+ + EL ER +KL+ Q L
Sbjct: 817 ERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERARKLREEEQLLR 876
Query: 277 RVS-EWHAVRHLKLREG-MYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
+ E R KLRE R + E R E K+ E + +EE
Sbjct: 877 QEEQELRQERDRKLREEEQLLRQEEQELRQE------------RDRKLREEEQLLQESEE 924
Query: 335 NKKLILRQKLHGSELRRAEKL-----QVIKSKQKEDLAREEAVLERR---KLIEAEKLQR 386
+ LR++ +LR E+L Q ++ ++ L EE +L+ R +L E+ ++
Sbjct: 925 ER---LRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEERLRRQERARK 981
Query: 387 LAEMQR--KKEEAQIRREEERKASSAAR--EARAIEQLRRKEERAKAQQEEAELLAQKLA 442
L E ++ ++EE ++R+E +RK + + R E+LRR+E K ++EE +L Q+L
Sbjct: 982 LREEEQLLRREEQELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELE 1041
Query: 443 ERLNESEQRRKIYLEQIRE 461
E+ + R+ EQIR+
Sbjct: 1042 EQFRQERDRKFRLEEQIRQ 1060
Score = 70.5 bits (171), Expect = 3e-11
Identities = 76/354 (21%), Positives = 157/354 (43%), Gaps = 35/354 (9%)
Query: 144 KDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFR 203
K + ++ EK + R + E+++++R + + ++++ E+ R
Sbjct: 1051 KFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRRERDRKFREEEQLLQER 1110
Query: 204 VSSRMSYSPSLGR-KSAERVRTLHDKLMSPEKKKKTTSD--LKKEAEEKHARALRIRSEL 260
R+ + + E++ ++L+ E+ +K + L +E+EE+ R +L
Sbjct: 1111 EEERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKL 1170
Query: 261 ETERVQKLQRTSQKLNRVSEWHAVRH---LKLREGMYARHQRSESRHEAFLAQVAKRAGD 317
E +R ++L R +R L +E R +R+ E Q+ ++
Sbjct: 1171 REEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERARKLREE--EQLLRQEEQ 1228
Query: 318 ESSKVNEVRFITSLNEENKKLILRQKLHGSELRRA------EKLQVIKSKQKEDLAREEA 371
E + + +F E ++L+ R++ ELRR E+ Q+++ +++E L R+E
Sbjct: 1229 ELRQERDRKF-----REEEQLLRREE---QELRRERDRKFREEEQLLQEREEERLRRQER 1280
Query: 372 VLERRK-----LIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRK--- 423
+ R+ L E ++ QRL + + ++ A+ + E K+ RE R E+ RR+
Sbjct: 1281 ARKLREEEEQLLFEEQEEQRLRQERDRRYRAEEQFAREEKSRRLERELRQEEEQRRRRER 1340
Query: 424 -----EERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPL 472
EE+ + QQEE + Q + E + RR++ R+ A + +SSPL
Sbjct: 1341 ERKFREEQLRRQQEEEQRRRQLRERQFREDQSRRQVLEPGTRQFARVPVRSSPL 1394
Score = 68.9 bits (167), Expect = 8e-11
Identities = 72/268 (26%), Positives = 127/268 (46%), Gaps = 24/268 (8%)
Query: 216 RKSAERVRTLHDKLMS--PEKKKKTTSDLKKE-AEEKHARALRIRSELETERV-----QK 267
R+ +R L D+ PE+++ + ++E AEE+ R R R E R Q+
Sbjct: 114 RQEDQRRFELRDRQFEDEPERRRWQKQEQERELAEEEEQRKKRERFEQHYSRQYRDKEQR 173
Query: 268 LQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRF 327
LQR + R E +R K R+ + R E + R ++ + +
Sbjct: 174 LQRQELEERRAEE-EQLRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERREQH 232
Query: 328 ITSLNEENKKLILRQKLHGSELRRAEKL----QVIKSKQK--EDLAREEAVLERRKLIEA 381
+L EE ++L LRQ+ E R ++L + I+ +++ E R E L R + +E
Sbjct: 233 ERALQEEEEQL-LRQRRWREEPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQ 291
Query: 382 EKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
E+ + E Q ++E +IR E+R RE R +EQ R+E++ K + EE ++
Sbjct: 292 EERR---EQQLRRELEEIREREQRLEQEERREQR-LEQEERREQQLKRELEEI----RER 343
Query: 442 AERLNESEQRRKIYLEQIRERANLRDQS 469
+RL + E+R ++ E++RE+A R +S
Sbjct: 344 EQRLEQEERREQLLAEEVREQARERGES 371
Score = 68.2 bits (165), Expect = 1e-10
Identities = 91/358 (25%), Positives = 159/358 (43%), Gaps = 44/358 (12%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
E+ R + L+R E+D+++R + +E R E + R ++
Sbjct: 563 EREYREEEKLQR-----EEDEKRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQERE 617
Query: 214 LGR-KSAERVRTLHDK---LMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQ 269
R + ER R L ++ L E++ + + K EE+ R R EL ER +KL+
Sbjct: 618 EERLRRQERERKLREEEQLLRQEEQELRQERERKLREEEQLLR--REEQELRQERERKLR 675
Query: 270 RTSQKLNRVSEWHAVRHLKLR----EGMYARHQRSESRHEAFLA-----QVAKRAGD--E 318
Q L E R + R E R + E R E Q+ +R
Sbjct: 676 EEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLR 735
Query: 319 SSKVNEVRFITSLNEENKKLILRQKLHGSELRRA------EKLQVIKSKQKEDLAREEA- 371
+ ++R L +E+++ LR++ +LRR E+ Q+++ +++E L R+E
Sbjct: 736 QERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERE 795
Query: 372 --VLERRKLIEAEKLQRLAEMQRKK---EEAQI--RREEER-KASSAAREARAIEQLRRK 423
+ E +L++ + +RL +R++ EE Q+ REEER + R+ R EQL R+
Sbjct: 796 RKLREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQ 855
Query: 424 E------ERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIR-ERANLRDQSSPLLR 474
E ERA+ +EE +LL Q+ E E +++ + + +R E LR + LR
Sbjct: 856 EEQELRQERARKLREEEQLLRQEEQELRQERDRKLREEEQLLRQEEQELRQERDRKLR 913
Score = 67.0 bits (162), Expect = 3e-10
Identities = 74/268 (27%), Positives = 126/268 (46%), Gaps = 38/268 (14%)
Query: 220 ERVRTLHDK---LMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLN 276
ER R L ++ L E+++ + +++ E+ R EL ER +KL+ Q L
Sbjct: 907 ERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQ 966
Query: 277 RVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK 336
E +LR AR R E Q+ +R E + + +F E +
Sbjct: 967 EREEE------RLRRQERARKLREEE-------QLLRREEQELRQERDRKF-----REEE 1008
Query: 337 KLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAE-MQRKKE 395
+L+ Q+ LRR E+ + + ++++ L R+E LE + E ++ RL E ++++KE
Sbjct: 1009 QLL--QEREEERLRRQERDRKFREEERQ-LRRQE--LEEQFRQERDRKFRLEEQIRQEKE 1063
Query: 396 EAQIRREEE----RKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQR 451
E Q+RR+E R+ R +QLRR ER + +EE +LL ++ ERL E+
Sbjct: 1064 EKQLRRQERDRKFREEEQQRRRQEREQQLRR--ERDRKFREEEQLLQEREEERLRRQERA 1121
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNK 479
RK +RE L + LLR+ ++
Sbjct: 1122 RK-----LREEEQLLRREEQLLRQERDR 1144
Score = 65.1 bits (157), Expect = 1e-09
Identities = 85/393 (21%), Positives = 170/393 (42%), Gaps = 42/393 (10%)
Query: 105 LLTSEVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNL- 163
LL ++ A +L +S L K ++H G G +LL + + ++ + D
Sbjct: 76 LLIFKLAQAAYYALGQASGLDEEK-RSH-GEGKGRLLQNRRQEDQRRFELRDRQFEDEPE 133
Query: 164 RRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAE--- 220
RR+ Q E+++E L + K++ +E S +R + L + AE
Sbjct: 134 RRRWQKQEQERE-----LAEEEEQRKKRERFEQHYSRQYRDKEQRLQRQELEERRAEEEQ 188
Query: 221 ----RVRTLHDKLMSPEKKKKTTSDLKKEAEEK----------HARALRIRSE--LETER 264
+ R + + + +++ +LK+E E+ H RAL+ E L R
Sbjct: 189 LRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERREQHERALQEEEEQLLRQRR 248
Query: 265 VQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSES--RHEAFLAQVAKRAGDESSKV 322
++ R Q+L R E ++ RE + +R E R E L Q +R ++
Sbjct: 249 WREEPREQQQLRRELE-----EIREREQRLEQEERREQQLRREQRLEQEERREQQLRREL 303
Query: 323 NEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAE 382
E+R E ++ + +++ L + E+ + ++ E++ E LE+ + E
Sbjct: 304 EEIR-------EREQRLEQEERREQRLEQEERREQQLKRELEEIREREQRLEQEERREQL 356
Query: 383 KLQRLAEMQRKKEEAQIRREEERKASSA-AREARAIEQLRRKEERAKAQQEEAELLAQKL 441
+ + E R++ E+ RR + + S A AR+++ + RR+EE++ Q +E ++
Sbjct: 357 LAEEVREQARERGESLTRRWQRQLESEAGARQSKVYSRPRRQEEQSLRQDQERRQRQERE 416
Query: 442 AERLNESEQRRKIYLEQIRERANLRDQSSPLLR 474
E ++ ++++ E+ ER R + P LR
Sbjct: 417 RELEEQARRQQQWQAEEESERRRQRLSARPSLR 449
Score = 64.3 bits (155), Expect = 2e-09
Identities = 73/329 (22%), Positives = 145/329 (43%), Gaps = 19/329 (5%)
Query: 165 RQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRT 224
R+ QL ++++++ + +E+R L ++ R S + R
Sbjct: 449 RERQLRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDRE 508
Query: 225 LHDKLMSPEKKKKTTSDLKKEAEEK-HARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
+ + L++EA+ + H + + + ++LQR ++ R E+
Sbjct: 509 RRRRQQEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYRE 568
Query: 284 VRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQK 343
L+ E R Q E ++ ++ + +E + ++R L +E ++ LR++
Sbjct: 569 EEKLQREEDEKRRRQERERQYR----ELEELRQEEQLRDRKLREEEQLLQEREEERLRRQ 624
Query: 344 LHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRK-KEEAQI--R 400
+LR E+L + + +Q+ RE + E +L+ E+ + E +RK +EE Q+
Sbjct: 625 ERERKLREEEQL-LRQEEQELRQERERKLREEEQLLRREEQELRQERERKLREEEQLLQE 683
Query: 401 REEER-KASSAAREARAIEQLRRKEERAKAQQEEAELLAQ----KLAERLNESEQRRKI- 454
REEER + AR+ R EQL R+EE+ Q+ E +L + + E+L E+ RK+
Sbjct: 684 REEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRKLR 743
Query: 455 ----YLEQIRERANLRDQSSPLLRRSLNK 479
L++ E R + LRR ++
Sbjct: 744 EEEQLLQESEEERLRRQEREQQLRRERDR 772
Score = 63.2 bits (152), Expect = 4e-09
Identities = 72/321 (22%), Positives = 143/321 (44%), Gaps = 47/321 (14%)
Query: 155 KNPRSTDNLRRQMQ-LPEKDK-----EKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRM 208
+ PR LRR+++ + E+++ E+R L + +E+R + +
Sbjct: 251 EEPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQQL----------- 299
Query: 209 SYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKL 268
R+ E +R +L E++++ + E EE+ + L+ E ER Q+L
Sbjct: 300 -------RRELEEIREREQRLEQEERREQ-----RLEQEERREQQLKRELEEIREREQRL 347
Query: 269 QRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI 328
++ ++ ++E ++RE +R ES + Q+ AG SKV +
Sbjct: 348 EQEERREQLLAE-------EVRE---QARERGESLTRRWQRQLESEAGARQSKV----YS 393
Query: 329 TSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKL-QRL 387
+E + L Q+ + R E L+ +Q++ A EE+ R++L L +R
Sbjct: 394 RPRRQEEQSLRQDQERRQRQERERE-LEEQARRQQQWQAEEESERRRQRLSARPSLRERQ 452
Query: 388 AEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNE 447
+ ++E+ Q REEE + +E + +E+ + + R +AQQ + E Q+ ER
Sbjct: 453 LRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDRERRRR 512
Query: 448 SEQRR--KIYLEQIRERANLR 466
+++R + + Q++E A R
Sbjct: 513 QQEQRPGQTWRWQLQEEAQRR 533
Score = 58.9 bits (141), Expect = 8e-08
Identities = 79/357 (22%), Positives = 157/357 (43%), Gaps = 35/357 (9%)
Query: 138 DKLLSLKDKAPTEVINEKNPRSTDN--LRRQMQLPEKDKEKRSTSLGKSMNAWKEK---- 191
++L K + E I E+ R + L+R+++ E+ + +R +++ +E+
Sbjct: 187 EQLRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERREQHERALQEEEEQLLRQ 246
Query: 192 RNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTS-DLKKEAEEKH 250
R W + ++ R+ E +R +L E++++ + + E EE+
Sbjct: 247 RRWREEPREQQQL-----------RRELEEIREREQRLEQEERREQQLRREQRLEQEERR 295
Query: 251 ARALRIRSELETERVQKLQRTSQKLNRVS-EWHAVRHLKLR-EGMYARHQR--SESRHEA 306
+ LR E ER Q+L++ ++ R+ E + LK E + R QR E R E
Sbjct: 296 EQQLRRELEEIREREQRLEQEERREQRLEQEERREQQLKRELEEIREREQRLEQEERREQ 355
Query: 307 FLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDL 366
LA+ + E + R+ L E RQ S RR E+ +S +++
Sbjct: 356 LLAEEVREQARERGESLTRRWQRQLESEAGA---RQSKVYSRPRRQEE----QSLRQDQE 408
Query: 367 AREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREE-ERKASSAAREARAIEQLRRKEE 425
R+ ER E E+ R + + +EE++ RR+ + S R+ RA E+ + +E+
Sbjct: 409 RRQRQERER----ELEEQARRQQQWQAEEESERRRQRLSARPSLRERQLRA-EERQEQEQ 463
Query: 426 RAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQ 482
R + ++E+ Q+L E + +R+ +Q++E + ++ R+ + GQ
Sbjct: 464 RFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDRERRRRQQEQRPGQ 520
>TRHY_HUMAN (Q07283) Trichohyalin
Length = 1898
Score = 77.8 bits (190), Expect = 2e-13
Identities = 84/360 (23%), Positives = 150/360 (41%), Gaps = 29/360 (8%)
Query: 139 KLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDIL 198
+LL L+ K E ++ R + + EK+ KR T L K +E+
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEE---EEKEWRKRETVLRKEEEKLQEEE------ 264
Query: 199 SSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRS 258
P R L + + +R + +++ + L+++ EE+ R
Sbjct: 265 --PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 259 ELETERVQKLQRTSQKLNRVSEWHAVRHLKL-----REGMYARHQRSESRHEAFLAQVAK 313
E + R Q+ +R Q+L R E + L+ R R ++ E R E Q +
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE----QQLR 378
Query: 314 RAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVL 373
R +E + ++R L E + +Q +LRR ++L+ + ++E R E L
Sbjct: 379 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 438
Query: 374 ER----RKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKA 429
R R+ E E+ ++ E +R+++ + +EE R E EQ RRK++ +
Sbjct: 439 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 498
Query: 430 QQEEAELLAQKL-AERLNESEQRRKIYL----EQIRERANLRDQSSPLLRRSLNKDGQGR 484
Q+EE KL E E ++RR+ L E+ RE+ R + L++ L + Q R
Sbjct: 499 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 558
Score = 75.1 bits (183), Expect = 1e-12
Identities = 86/346 (24%), Positives = 149/346 (42%), Gaps = 44/346 (12%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
E+ R LRR+ QL + + +R L + +E++ R ++
Sbjct: 387 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ---------LRREQQLRREQQ 437
Query: 214 LGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQ 273
L R+ R ++ ++++ LK+E EE+ ++ E ETER ++ +R Q
Sbjct: 438 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW---LKREEETERHEQERRKQQ 494
Query: 274 KLNRVSEWHAVRHLKL-----REGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI 328
E R LKL RE R Q+ E Q KR +E +R
Sbjct: 495 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 554
Query: 329 TSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQR-- 386
L E ++ L Q L E +R E+ + + ++E R + +L+R + ++L+R
Sbjct: 555 QQLRREQEER-LEQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 613
Query: 387 --LAEMQRKKEEAQIRREEERK-----------------ASSAAREARAIEQLRRKEERA 427
E + K+EE + +EER+ S +E R EQLRR+++
Sbjct: 614 EERLEQRLKREEVERLEQEERRDERLKREEPEEERRHELLKSEEQEERRHEQLRREQQER 673
Query: 428 KAQ----QEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQS 469
+ Q +EE E L Q+L +R +E E+R + E+ +E+A R +S
Sbjct: 674 REQRLKREEEEERLEQRL-KREHEEERREQELAEEEQEQARERIKS 718
Score = 74.7 bits (182), Expect = 1e-12
Identities = 92/321 (28%), Positives = 144/321 (44%), Gaps = 42/321 (13%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKS-------MNAWKEKRNWEDILSSPFRVSS 206
E+ R LRR+ QL + +E+R + +E+R+W R
Sbjct: 429 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 488
Query: 207 RMSYSPSLGRKSAERVRTLHDKLMSPEKKK---KTTSDLKKEAEEKHARALRIRSELETE 263
L R E R KL E+++ + L++E EE+ R R++ + E E
Sbjct: 489 ERR-KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER--REQRLKRQEEEE 545
Query: 264 RVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVN 323
R+Q+ R+ Q+L R E + LK E +R E R L + + D+ K
Sbjct: 546 RLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERREQR----LKREQEERRDQLLKRE 601
Query: 324 EVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERR-KLIEAE 382
E R L E ++ L Q+L E+ R E+ + ++ E L REE ERR +L+++E
Sbjct: 602 EERRQQRLKREQEER-LEQRLKREEVERLEQ----EERRDERLKREEPEEERRHELLKSE 656
Query: 383 KLQRLAEMQRKKEEAQIRRE-EERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
+ Q ++ Q+RRE +ER+ RE E+ R E+R K + EE E Q+L
Sbjct: 657 E-------QEERRHEQLRREQQERREQRLKRE----EEEERLEQRLKREHEE-ERREQEL 704
Query: 442 AERLNESEQRRKIYLEQIRER 462
AE E EQ R E+I+ R
Sbjct: 705 AE--EEQEQAR----ERIKSR 719
Score = 73.6 bits (179), Expect = 3e-12
Identities = 69/308 (22%), Positives = 135/308 (43%), Gaps = 31/308 (10%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
++ + LRR+ QL K +E+R + + + E+ R
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR---------- 340
Query: 214 LGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQ 273
R+ ER +L +++++ L++E EE+ R ++R E E ER ++ R Q
Sbjct: 341 --REQEER---REQQLRREQEEERREQQLRREQEEER-REQQLRREQEEERREQQLRREQ 394
Query: 274 KLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNE 333
+L R + LR R ++ R + + R + + ++R L
Sbjct: 395 QLRREQQ--------LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 446
Query: 334 ENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRK 393
E ++ QK H E RR ++L+ + ++++ L REE + ++L+R E +R+
Sbjct: 447 EQEEERHEQK-HEQE-RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 504
Query: 394 KEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRK 453
+ ++ EE R+ + EQ R+E+R K Q+EE ++L +RL +Q R+
Sbjct: 505 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE-----ERLQQRLRSEQQLRR 559
Query: 454 IYLEQIRE 461
E++ +
Sbjct: 560 EQEERLEQ 567
Score = 73.2 bits (178), Expect = 4e-12
Identities = 82/332 (24%), Positives = 145/332 (42%), Gaps = 24/332 (7%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSR-MSYSP 212
EK R R+ +L ++E++ ++ +E+ ++ + R +
Sbjct: 834 EKEQRGRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQKWRW 893
Query: 213 SLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEE--KHARALRIRSELETERVQKLQR 270
L + R TL+ K E+ +K L++E EE + R R R E E + ++ Q
Sbjct: 894 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 953
Query: 271 TSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVA-KRAGDESSKVNEVRFIT 329
++ + E R + RE Y + ++ + + E L + KR E K + R
Sbjct: 954 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK--KYREEE 1011
Query: 330 SLNEENKKLIL--RQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRL 387
L +E ++L+ R+K E R + + +++E L REE E+R+L E E+ R
Sbjct: 1012 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER--EKRRLQERERQYRE 1069
Query: 388 AEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNE 447
E +++EE + E E R + +E+ RKEE QQEE +LL ++ +R +
Sbjct: 1070 EEELQQEEEQLLGEERE------TRRRQELERQYRKEEEL--QQEEEQLLREEPEKRRRQ 1121
Query: 448 SEQRRKIYLEQIRERANLRDQSSPLLRRSLNK 479
+R Q RE L+ + LLR K
Sbjct: 1122 ERER------QCREEEELQQEEEQLLREEREK 1147
Score = 72.4 bits (176), Expect = 7e-12
Identities = 81/367 (22%), Positives = 155/367 (42%), Gaps = 39/367 (10%)
Query: 158 RSTDNLRRQMQLP-EKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGR 216
R + RR+ QL E+++E+R L + +E+R + R ++ L R
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQE--EERREQQLRREQQLRREQQLRREQQLRR 410
Query: 217 KSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELET-ERVQKLQRTSQKL 275
+ R ++ + E++ + L++E + + + LR E E E+ + +R Q+L
Sbjct: 411 EQQLR----REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 466
Query: 276 NRVSE----W-----HAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVR 326
R E W RH + R + + E R E +L K +E + E R
Sbjct: 467 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL----KLEEEERREQQERR 522
Query: 327 FITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLER---RKLIEAEK 383
E+ ++ R K E R ++L+ + ++E R E +L+R ++L + +
Sbjct: 523 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERR 582
Query: 384 LQRLAEMQRKKEEAQIRREEERKASSAAR-------------EARAIEQLRRKEERAKAQ 430
QRL Q ++ + ++REEER+ R E +EQ R++ER K +
Sbjct: 583 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRDERLKRE 642
Query: 431 QEEAELLAQKLAERLNESEQRRKIYLEQ--IRERANLRDQSSPLLRRSLNKDGQGRSTPN 488
+ E E + L E + ++ EQ RE+ R++ L + L ++ +
Sbjct: 643 EPEEERRHELLKSEEQEERRHEQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 702
Query: 489 NSSDDSQ 495
+++ Q
Sbjct: 703 ELAEEEQ 709
Score = 71.2 bits (173), Expect = 2e-11
Identities = 85/338 (25%), Positives = 148/338 (43%), Gaps = 38/338 (11%)
Query: 173 DKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGR--KSAERVRTLHDKLM 230
D+EKR+ GK + +++R ED R ++ P R K E+ R L +
Sbjct: 96 DEEKRARCDGKE-SLLQDRRTEEDQRRFEPR-DRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 231 SPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLR 290
EK+++ ++ +E+ R + E E R ++ Q S K + E+ L+ R
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 291 EGMYARH--------QRSESRHEAFLAQVAK---------RAGDESSKVNEVRFITSLNE 333
E + R QR E + F + K R +E + E + L E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 334 ENKKLILRQKLHGSELRRA---EKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEM 390
E ++L +KL ELRR E+ Q + ++++ L R++ R + E + Q E
Sbjct: 274 EEEQL---RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 391 QRKKEEAQIRREEERKASSAAR----EARAIEQLRRKEERAKAQQEEAELLAQKLAERLN 446
Q ++ E Q+RRE+E + R E R +QLRR++E + +Q+ L ++ E
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ----LRREQEEERR 386
Query: 447 ESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
E + RR+ +Q+R LR + + L ++ Q R
Sbjct: 387 EQQLRRE---QQLRREQQLRREQQLRREQQLRREQQLR 421
Score = 68.6 bits (166), Expect = 1e-10
Identities = 79/362 (21%), Positives = 157/362 (42%), Gaps = 29/362 (8%)
Query: 143 LKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPF 202
LK + E + ++ R + RR+ +L E+++E+ + + W+ W+ +
Sbjct: 678 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ----WQLESEADA 733
Query: 203 RVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELET 262
R S + +P GR A + + E+K++ S+L+ + EE RA R + E E
Sbjct: 734 RQSKVLLEAPQAGRAEAPQEQ---------EEKRRRESELQWQEEE---RAHRQQQEEEQ 781
Query: 263 ERV-----QKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGD 317
R Q +++ + R+S +R + R+ Q+ E R + +R
Sbjct: 782 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRGRQ 841
Query: 318 ESSKVNEVRFITSLNEENKKLILR---QKLHGSELRRAEKLQVIKSKQKEDLAREEAVLE 374
+ E++F+ EE ++L R Q+L E E + + +Q+ D + E
Sbjct: 842 RREREKELQFL----EEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQKWRWQLEE 897
Query: 375 RRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAI-EQLRRKEERAKAQQEE 433
RK + A ++ ++E Q+ +EEE + RE R EQ R+ E + QQEE
Sbjct: 898 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 957
Query: 434 AELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDD 493
+LL ++ +R + +R+ ++++++ P RR ++ + R ++
Sbjct: 958 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1017
Query: 494 SQ 495
Q
Sbjct: 1018 EQ 1019
Score = 65.9 bits (159), Expect = 7e-10
Identities = 65/308 (21%), Positives = 138/308 (44%), Gaps = 26/308 (8%)
Query: 157 PRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGR 216
P + LR++ QL ++++E+ + +++R + + + R
Sbjct: 910 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 969
Query: 217 KSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLN 276
+ + DK + ++++ + +K ++ + R EL+ E Q L+ +K
Sbjct: 970 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1029
Query: 277 RVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK 336
R EW E Y + + E L + ++ + + + R L +E +
Sbjct: 1030 R-QEW---------ERQYRKKDELQQEEEQLLREEREKRRLQERE-RQYREEEELQQEEE 1078
Query: 337 KLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEE 396
+L+ ++ E RR ++L+ + +++E+L +EE L R E EK +R ++ +EE
Sbjct: 1079 QLLGEER----ETRRRQELER-QYRKEEELQQEEEQLLRE---EPEKRRRQERERQCREE 1130
Query: 397 AQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYL 456
++++EEE+ RE R + RR++E + +EE EL QK +R + +QR +
Sbjct: 1131 EELQQEEEQ----LLREER---EKRRRQELERQYREEEELQRQKRKQRYRDEDQRSDLKW 1183
Query: 457 EQIRERAN 464
+ E+ N
Sbjct: 1184 QWEPEKEN 1191
Score = 62.0 bits (149), Expect = 9e-09
Identities = 67/274 (24%), Positives = 125/274 (45%), Gaps = 17/274 (6%)
Query: 212 PSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRT 271
P L R+ E+ + HD+ ++K + L +E EE+ R R E Q+L+R
Sbjct: 1605 PQLRRQEREQ-QLRHDR----DRKFREEEQLLQEGEEQQLRRQE-RDRKFREEEQQLRRQ 1658
Query: 272 SQKLNRVSEWHAVRHLKLREGMYARHQ-RSESRHEAFLAQVAKRAGDESSKVNEVRFITS 330
++ + E +R +L Q R E+ E Q R E ++ R
Sbjct: 1659 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1718
Query: 331 LNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVL-ERRKLIEAEKLQRLAE 389
L + + R++ +LR+ + Q ++S++ + REE L + R+ + QR +
Sbjct: 1719 LRRQERDRKFREE---EQLRQGREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1775
Query: 390 MQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESE 449
+ ++E+ Q+ +E+R R+ RA EQ +E K+++EE EL ++ E+ E
Sbjct: 1776 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE---KSRREEQELWQEE--EQKRRQE 1830
Query: 450 QRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQG 483
+ RK+ E IR R +Q + +++G+G
Sbjct: 1831 RERKLREEHIR-RQQKEEQRHRQVGEIQSQEGKG 1863
Score = 60.5 bits (145), Expect = 3e-08
Identities = 79/342 (23%), Positives = 146/342 (42%), Gaps = 33/342 (9%)
Query: 164 RRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVR 223
R + QL ++++++ + + + R FR S P RK E +
Sbjct: 1429 REEQQLHRQERDRKFLEEEQQLRRQERDRK--------FREQELRSQEPE--RKFLEEEQ 1478
Query: 224 TLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
LH + K + L+++ + R R R E E++++ +R Q+L+R
Sbjct: 1479 QLH-RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ-EREEQQLSRQE---- 1532
Query: 284 VRHLKLR-EGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITS---LNEENKKLI 339
R K R E R Q E + Q+ ++ G + + + +F L E ++ +
Sbjct: 1533 -RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQEDRKFREDEQLLQEREEQQL 1591
Query: 340 LRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQR----KKE 395
RQ+ L +L+ + +Q+ R+ E +L++ + Q+L +R ++E
Sbjct: 1592 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1651
Query: 396 EAQIRREE-ERKASSAAREAR--AIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRR 452
E Q+RR+E ERK ++ R +E+ R+EE+ + + E+ +L Q+ ++ E EQ
Sbjct: 1652 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ-- 1709
Query: 453 KIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDS 494
L RE LR Q R + QGR S +S
Sbjct: 1710 ---LRPEREEQQLRRQERDRKFREEEQLRQGREEQQLRSQES 1748
Score = 58.9 bits (141), Expect = 8e-08
Identities = 63/274 (22%), Positives = 123/274 (43%), Gaps = 22/274 (8%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKK---EAEEKHARALRIRSELETER-VQKLQRT 271
R+ ER ++ + E++++ D + E E++ +R R R E E+ V++ +R
Sbjct: 1342 REERERKFLKEEQQLRLEEREQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1401
Query: 272 SQKLNRVSEWHAVRHLKLREGMYARHQRSES------RHEAFLAQVAKRAGDESSKVNEV 325
+ L + RH K RE +R E R FL + + E +
Sbjct: 1402 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1461
Query: 326 RFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQ 385
+ + S E K L Q+LH + R+ + LQ + ++++ ++ RK E E+L+
Sbjct: 1462 QELRSQEPERKFLEEEQQLHRQQ-RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1520
Query: 386 RLAEMQ-----------RKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEA 434
+ E Q R +E+ R+E+ERK ++ R E ++ + + +E+
Sbjct: 1521 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQEDRKFREDE 1580
Query: 435 ELLAQKLAERLNESEQRRKIYLEQIRERANLRDQ 468
+LL ++ ++L+ E+ RK E+ + R R+Q
Sbjct: 1581 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1614
Score = 58.2 bits (139), Expect = 1e-07
Identities = 70/325 (21%), Positives = 133/325 (40%), Gaps = 20/325 (6%)
Query: 164 RRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVR 223
R + QL ++++++ + + +++R + + R + RK E +
Sbjct: 1523 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE-DRKFREDEQ 1581
Query: 224 TLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
L ++ ++ + D K EE R +L +R +K + Q L E
Sbjct: 1582 LLQER--EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1639
Query: 284 VRHLKLREGMYARHQ-RSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQ 342
R + R+ Q R + R FL E ++ EE + LRQ
Sbjct: 1640 RRQERDRKFREEEQQLRRQERERKFL--------QEEQQLRRQELERKFREEEQ---LRQ 1688
Query: 343 KLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRRE 402
+ +LRR E+ + I +++ REE L R++ K + ++++ +EE Q+R +
Sbjct: 1689 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE--RDRKFREEEQLRQGREEQQLRSQ 1746
Query: 403 E-ERK--ASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQI 459
E +RK R+ R +QLR ++ K + EE +L ++ +RL + R+ EQ
Sbjct: 1747 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1806
Query: 460 RERANLRDQSSPLLRRSLNKDGQGR 484
+ R + L + K Q R
Sbjct: 1807 ATQEKSRREEQELWQEEEQKRRQER 1831
Score = 53.5 bits (127), Expect = 3e-06
Identities = 81/335 (24%), Positives = 149/335 (44%), Gaps = 40/335 (11%)
Query: 154 EKNPRSTDNLRRQMQ--LPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYS 211
E+ R + L+++ + L E+ +++R + +E + E+ L R R
Sbjct: 1094 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ-- 1151
Query: 212 PSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSEL----ETERVQK 267
L R+ E K + + SDLK + E + A+R E E+ ++
Sbjct: 1152 -ELERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1210
Query: 268 LQRTSQKLNRVSEWHAVRHL------------KLREGMYARHQRSESRHEAFLAQVAKRA 315
L+ SQ +R S+ ++HL + R RH E + E + AKR
Sbjct: 1211 LE-DSQVRDRQSQ-QDLQHLLGEQQERDREQERRRWQQANRHFPEEEQLEREEQKEAKRR 1268
Query: 316 GDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLER 375
+S + ++ L EE ++ RQ+ ++ + E+ Q+++ ++++ L R+E
Sbjct: 1269 DRKSQEEKQL-----LREEREEKRRRQE---TDRKFREEEQLLQEREEQPLLRQE---RD 1317
Query: 376 RKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREAR--AIEQLRRKEERAKAQQEE 433
RK E E L + + +EE ++R E ERK ++ R EQLR+ +R K ++EE
Sbjct: 1318 RKFREEELLHQEQGRKFLEEEQRLREERERKFLKEEQQLRLEEREQLRQDRDR-KFREEE 1376
Query: 434 AELLAQKLAERLNESEQRRKIYLEQIRERANLRDQ 468
+L Q+ + E EQ+ + Q RER L ++
Sbjct: 1377 QQLSRQERDRKFREEEQQVR---RQERERKFLEEE 1408
Score = 51.6 bits (122), Expect = 1e-05
Identities = 68/315 (21%), Positives = 143/315 (44%), Gaps = 36/315 (11%)
Query: 154 EKNPRSTDNLRRQMQ--LPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYS 211
E+ R D L+++ + L E+ +++R + +E + E+ L R + R
Sbjct: 1034 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1093
Query: 212 PSLGRKSAERVRTLHDKLM--SPEKKKKTTSD--LKKEAEEKHARALRIRSELETERVQK 267
RK E ++ ++L+ PEK+++ + ++E E + +R E E R Q+
Sbjct: 1094 ERQYRKE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1152
Query: 268 LQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRF 327
L+R + E ++ K ++ QRS+ + + E K N VR
Sbjct: 1153 LER------QYREEEELQRQKRKQRYRDEDQRSDLKWQW-----------EPEKENAVR- 1194
Query: 328 ITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRL 387
+NK + + + R+ E QV + ++DL + + E+++ ++ +R
Sbjct: 1195 ------DNK--VYCKGRENEQFRQLEDSQVRDRQSQQDL--QHLLGEQQERDREQERRRW 1244
Query: 388 AEMQRK-KEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLN 446
+ R EE Q+ REE+++A R+++ +QL R+E K +++E + ++ + L
Sbjct: 1245 QQANRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1304
Query: 447 ESEQRRKIYLEQIRE 461
E E++ + E+ R+
Sbjct: 1305 EREEQPLLRQERDRK 1319
Score = 50.8 bits (120), Expect = 2e-05
Identities = 59/260 (22%), Positives = 117/260 (44%), Gaps = 29/260 (11%)
Query: 227 DKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRH 286
++L E+K+ D K + E++ R R E +K + Q L E +R
Sbjct: 1255 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLLRQ 1314
Query: 287 LKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK-KLILRQKLH 345
+ R + + E H+ + ++ +E ++ E R L EE + +L R++L
Sbjct: 1315 ERDR-----KFREEELLHQ----EQGRKFLEEEQRLREERERKFLKEEQQLRLEEREQLR 1365
Query: 346 GSELR--RAEKLQVIKSKQKEDLAREEAVLER----RKLIEAEKLQRLAEMQRKKEEAQI 399
R R E+ Q+ + ++ EE + R RK +E E+ R ++ +EE Q+
Sbjct: 1366 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1425
Query: 400 ----------RREEERKASSAAREARAIEQLRR-KEERAKAQQEEAELLAQKLAERLNES 448
R+E +RK ++ R E+ R+ +E+ ++Q+ E + L ++ ++L+
Sbjct: 1426 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE--QQLHRQ 1483
Query: 449 EQRRKIYLEQIRERANLRDQ 468
+++RK E+ + R R Q
Sbjct: 1484 QRQRKFLQEEQQLRRQERGQ 1503
Score = 49.3 bits (116), Expect = 6e-05
Identities = 72/330 (21%), Positives = 140/330 (41%), Gaps = 31/330 (9%)
Query: 154 EKNPRSTDNLRRQMQLPEK-DKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSP 212
E+ R L RQ + E+ ++KR K WE + R +
Sbjct: 1144 EREKRRRQELERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK-- 1201
Query: 213 SLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERV---QKLQ 269
GR++ E+ R L D + + ++ L E +E+ R R + ++L+
Sbjct: 1202 --GREN-EQFRQLEDSQVRDRQSQQDLQHLLGEQQERDREQERRRWQQANRHFPEEEQLE 1258
Query: 270 RTSQKLNRVSEWHAVRHLKL-REGMYARHQRSES-----RHEAFLAQVAKRAGDESSKVN 323
R QK + + + +L RE + +R E+ E L + ++ +
Sbjct: 1259 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLLRQERDR 1318
Query: 324 EVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEK 383
+ R L++E + L ++ LR + + +K +Q+ L E + + R E+
Sbjct: 1319 KFREEELLHQEQGRKFLEEE---QRLREERERKFLKEEQQLRLEEREQLRQDRDRKFREE 1375
Query: 384 LQRLAEMQR----KKEEAQIR-REEERKASSAAREARAIEQLRRKEERAKAQQEEAELLA 438
Q+L+ +R ++EE Q+R +E ERK E+ + ++ER + +EE +LL
Sbjct: 1376 EQQLSRQERDRKFREEEQQVRRQERERKFLE--------EEQQLRQERHRKFREEEQLLQ 1427
Query: 439 QKLAERLNESEQRRKIYLEQIRERANLRDQ 468
++ ++L+ E+ RK E+ + R RD+
Sbjct: 1428 EREEQQLHRQERDRKFLEEEQQLRRQERDR 1457
>INCE_MOUSE (Q9WU62) Inner centromere protein
Length = 880
Score = 77.0 bits (188), Expect = 3e-13
Identities = 79/321 (24%), Positives = 149/321 (45%), Gaps = 32/321 (9%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKE--KRNWEDILSSPFRVSSRMSYSPSLGRKSAE 220
LR + +K++ + +L + K KRN +P RV + S+ K +
Sbjct: 466 LRTFLHTVQKNQMLMTPTLASRSSVMKSFIKRN------TPLRVDPKCSFV----EKERQ 515
Query: 221 RVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSE 280
R+ +L K + +++++ K E+K R E++ +R ++L++ Q RV +
Sbjct: 516 RLESLRRKEEAEQRRRQ------KVEEDKRRRL----EEVKLKREERLRKVLQARERVEQ 565
Query: 281 WHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLIL 340
+ ++ + +++E E LA+ AK+ + K+ EV EE ++L
Sbjct: 566 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEKAKKKAT-AKKMEEVEARRKQEEEARRLRW 624
Query: 341 RQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEA--Q 398
Q+ E R E LQ ++KE+ E R+L E + +R E +R+++E Q
Sbjct: 625 LQQ-EEEERRHQEMLQ----RKKEEEQERRKAAEARRLAEQREQERRREQERREQERREQ 679
Query: 399 IRREEERKASSAA-REARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLE 457
RRE+ERK +E + R +ER KA + + E L ++L E+ + EQ+R + +
Sbjct: 680 ERREQERKEQERREQEQERLRAKREMQEREKALRLQKERLQKELEEKKRKEEQQR-LAEQ 738
Query: 458 QIRERANLRDQSSPLLRRSLN 478
Q++E + + R+ LN
Sbjct: 739 QLQEEQAKKAKEVAAARKVLN 759
Score = 66.2 bits (160), Expect = 5e-10
Identities = 73/248 (29%), Positives = 113/248 (45%), Gaps = 32/248 (12%)
Query: 245 EAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRH 304
E E + +LR + E E R QK++ K R+ E R +LR+ + AR + + +
Sbjct: 511 EKERQRLESLRRKEEAEQRRRQKVEE--DKRRRLEEVKLKREERLRKVLQARERVEQMKE 568
Query: 305 EAF--LAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQ 362
E + Q + +++ K E R L E+ KK +K+ E RR KQ
Sbjct: 569 EKKKQIEQKFAQIDEKTEKAKEER----LAEKAKKKATAKKMEEVEARR---------KQ 615
Query: 363 KEDLAREEAVLERRKLIEAEKLQRLAEM-QRKKEEAQIRRE--EERKASSAAREARAIEQ 419
+E+ R R L + E+ +R EM QRKKEE Q RR+ E R+ + + R EQ
Sbjct: 616 EEEARR------LRWLQQEEEERRHQEMLQRKKEEEQERRKAAEARRLAEQREQERRREQ 669
Query: 420 LRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPL---LRRS 476
RR++ER + ++ E E +K ER + ++R + E LR Q L L
Sbjct: 670 ERREQERREQERREQE---RKEQERREQEQERLRAKREMQEREKALRLQKERLQKELEEK 726
Query: 477 LNKDGQGR 484
K+ Q R
Sbjct: 727 KRKEEQQR 734
>PLE1_CRIGR (Q9JI55) Plectin 1 (PLTN) (PCN) (300-kDa intermediate
filament-associated protein) (IFAP300) (Fragment)
Length = 4473
Score = 75.5 bits (184), Expect = 8e-13
Identities = 121/498 (24%), Positives = 210/498 (41%), Gaps = 54/498 (10%)
Query: 124 LATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDN-------LRRQMQLPEKDKEK 176
LA T L + A+ ++LK+K E NE+ R ++ L Q L + D E+
Sbjct: 1765 LAAISEATRLKTEAE--IALKEK---EAENERLRRLAEDEAFQRRRLEEQAALHKADIEE 1819
Query: 177 RSTSLGKSMNAWKEKRNW--EDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEK 234
R L K+ + E++ ED L +V + K+A L +L
Sbjct: 1820 RLAQLRKASESELERQKGLVEDTLRQRRQVEEEILALKVSFEKAAAGKAELELELGRIRS 1879
Query: 235 KKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMY 294
+ T K++AE++ AR ++ +E E R + +R + L E R L E
Sbjct: 1880 SAEDTMRSKEQAEQEAARQRQLAAEEEQRRREAEERVQKSLAAEEEAARQRKAALEEVER 1939
Query: 295 ARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELR-RAE 353
+ + E+R ++ +RA ES++ ++ + K+L +K H ++ R E
Sbjct: 1940 LKAKVEEAR------RLRERAEQESARQLQL----AQEAAQKRLQAEEKAHAFVVQQREE 1989
Query: 354 KLQVIKSKQKEDLAR--EEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREE------ER 405
+LQ +++ L R EA RR EAE+ + AE + + Q+ E E
Sbjct: 1990 ELQQTLQQEQSMLERLRGEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEE 2049
Query: 406 KASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQ-IRERAN 464
+A + A+ A E+LR++ E+ A++ +AE A K + + ++ K + EQ +R++A
Sbjct: 2050 QAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQ 2109
Query: 465 LRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIG----SITLQHSMKRR 520
+ +Q LR L + +S + + + + S+ +Q +
Sbjct: 2110 V-EQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGK 2168
Query: 521 IK-RIRQKLMAL-------KYEFLEPPLGGESAGIGYRVAVGAARAKVGRWLQELQRLRQ 572
+K RI + AL FLE E A +VA AAR V QE RLRQ
Sbjct: 2169 LKARIEAENRALILRDKDNTQRFLE-----EEAEKMKQVAEEAARLSVA--AQEAARLRQ 2221
Query: 573 ARKEGATSIGLIISEMIK 590
+E + +M+K
Sbjct: 2222 LAEEDLAQQRALAEKMLK 2239
Score = 62.0 bits (149), Expect = 9e-09
Identities = 107/491 (21%), Positives = 211/491 (42%), Gaps = 62/491 (12%)
Query: 16 EAFRKIQQERASLKLSNNTEHAMSKCLTSESVGNMNGTHNAKNSRTKSRKHIGSSDANQG 75
EA R+ Q E+A+LK + M K + + + T R + +D +
Sbjct: 2071 EAARRAQAEQAALKQKQAADAEMEKH-KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKS 2129
Query: 76 NLNVKKHNIEGTKPCDAIRVQKGYIPPESLLTSEVDLAKLPSL------ENSSALATAKV 129
L+ + ++ + +A R Q+ + E L + V + +L L EN + + K
Sbjct: 2130 ILDEELQRLKA-EVTEAAR-QRSQVE-EELFSVRVQMEELGKLKARIEAENRALILRDKD 2186
Query: 130 KTH--LGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNA 187
T L A+K+ + ++A + + R QL E+D ++ K +
Sbjct: 2187 NTQRFLEEEAEKMKQVAEEAARLSV------AAQEAARLRQLAEEDLAQQRALAEKML-- 2238
Query: 188 WKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAE 247
KEK + + + L ++ A R++ DK ++ + T ++ E
Sbjct: 2239 -KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ--EDKEQMAQQLVEETQGFQRTLE 2295
Query: 248 EKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSE--SRHE 305
+ R L + +E E +++ + + + +E A R K E + + R+E ++ +
Sbjct: 2296 VERQRQLEMSAEAERLKLRMAEMSRAQAR--AEEDAQRFRKQAEEIGEKLHRTELATQEK 2353
Query: 306 AFLAQVAK----RAGDESSKVNEVRFITSLNEENKKLILRQKL---HGSELRRAEKLQVI 358
L Q + ++ ++ ++ E I L E +KL KL E++ ++ Q++
Sbjct: 2354 VTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLKQEAKLLQLKSEEMQTVQQEQIL 2411
Query: 359 KSKQ---KEDLAREEAVLERRKLIEAE--KLQRL-------AEMQRKKEEAQIRREEERK 406
+ Q K L+ ++++L+R + IE E KL++L A+ R++++ Q R+ E+ K
Sbjct: 2412 QETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQRQMEQEK 2471
Query: 407 ASSAA-------REARAIEQLRRKEERAK----AQQEEAELLA---QKLAERLNESEQRR 452
A R+ A E +RRK+E + +Q++ +LLA Q+L ERL E+
Sbjct: 2472 QELVASMEEARRRQCEAEEAVRRKQEELQHLELQRQQQEKLLAEENQRLRERLQRLEEEH 2531
Query: 453 KIYLEQIRERA 463
+ L E A
Sbjct: 2532 RAALAHSEEIA 2542
Score = 58.9 bits (141), Expect = 8e-08
Identities = 111/510 (21%), Positives = 206/510 (39%), Gaps = 54/510 (10%)
Query: 117 SLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEK 176
+LE + A ++++ S A+K L+ E + R R Q Q + E+
Sbjct: 1492 ALETAQRSAEVELQSKRASFAEKTAQLERTLQEEHVTVTQLREKAERRAQQQA---EAER 1548
Query: 177 RSTSLGKSMNAWKEKRNWEDILS-SPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKK 235
+ + W+ K N L V+ + S + + K E + E++
Sbjct: 1549 AREEAERELERWQLKANEALRLRLQAEEVAQQRSLAQADAEKQKEEAEREARRRGKAEEQ 1608
Query: 236 KKTTSDLKKEAEEKHARAL------RIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKL 289
+L ++ EK + R+ +E E R++ ++ ++ E R
Sbjct: 1609 AVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR--LQ 1666
Query: 290 REGMYARHQRSESRHEAFLAQVAKRAGDE---SSKVNEVRFITSLNEENKKLILRQKLHG 346
RE A H+R E EA LA+V RA E +SK S +E++K+ + +
Sbjct: 1667 REATAATHKRQEL--EAELAKV--RAEMEVLLASKARAEEESRSTSEKSKQRLEAEADRF 1722
Query: 347 SEL-RRAEKLQVIKSKQK-------EDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQ 398
EL A +L+ + + K ED AR+ A ER + EKL ++E R K EA+
Sbjct: 1723 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER---VLTEKLAAISEATRLKTEAE 1779
Query: 399 IRREEERKASSAAR---EARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIY 455
I +E+ + R E A ++ R +E+ A + + E LAQ +E E+++ +
Sbjct: 1780 IALKEKEAENERLRRLAEDEAFQRRRLEEQAALHKADIEERLAQLRKASESELERQKGLV 1839
Query: 456 LEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIGSITLQH 515
+ +R+R + ++ L+ S K G++ + LG T++
Sbjct: 1840 EDTLRQRRQVEEEIL-ALKVSFEKAAAGKA-----------ELELELGRIRSSAEDTMRS 1887
Query: 516 SMKRRIKRIRQKLMALK--------YEFLEPPLGGESAGIGYRVAVGAARAKVGRWLQEL 567
+ + RQ+ +A + E ++ L E R A ++ ++E
Sbjct: 1888 KEQAEQEAARQRQLAAEEEQRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 1947
Query: 568 QRLRQ-ARKEGATSIGLIISEMIKYLEGKD 596
+RLR+ A +E A + L K L+ ++
Sbjct: 1948 RRLRERAEQESARQLQLAQEAAQKRLQAEE 1977
Score = 53.1 bits (126), Expect = 4e-06
Identities = 57/273 (20%), Positives = 119/273 (42%), Gaps = 17/273 (6%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARA-LRIRSELETERVQKLQRTSQKLNRV 278
++ R++ ++L + + K + E R+ +RI E+ R+Q Q+
Sbjct: 1339 QQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAE 1398
Query: 279 SEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKL 338
E A+R A Q+ +++ EA ++ ++ DES + + +L + +
Sbjct: 1399 GELQALR----ARAEEAEAQKRQAQEEA--ERLRRQVQDESQRKRQAEAELALRVKAQAE 1452
Query: 339 ILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQ 398
++K L+ E+L++ + + L + +A R+ + E QR AE++ + + A
Sbjct: 1453 AAQEKQRA--LQALEELRLQAEEAERRLRQAQAERARQVQVALETAQRSAEVELQSKRAS 1510
Query: 399 IRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ-------R 451
+ + + E + QLR K ER QQ EAE A++ AER E Q R
Sbjct: 1511 FAEKTAQLERTLQEEHVTVTQLREKAERRAQQQAEAE-RAREEAERELERWQLKANEALR 1569
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
++ E++ ++ +L + + ++ + R
Sbjct: 1570 LRLQAEEVAQQRSLAQADAEKQKEEAEREARRR 1602
Score = 44.7 bits (104), Expect = 0.002
Identities = 100/522 (19%), Positives = 200/522 (38%), Gaps = 69/522 (13%)
Query: 109 EVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQ 168
E+ L KL + + SA+ K+KT +SL ++ T+ E + L+
Sbjct: 994 ELTLGKLEQVRSLSAIYLEKLKT---------ISLVIRS-TQGAEEVLKAHEEQLKEAQA 1043
Query: 169 LPEKDKEKRSTSLG-KSMNAWKEKRN-----WEDILSSPFRVSSRMSYSPSLGRKSAERV 222
+P +E +T K + A E + D L V R+ ER
Sbjct: 1044 VPATLQELEATKASLKKLRAQAEAQQPVFDTLRDELRGAQEVGERLQQRHGERDVEVERW 1103
Query: 223 RTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWH 282
R ++L+ + D+++ E+ R LR E LQ ++ ++
Sbjct: 1104 RERVNQLLERWQAVLAQIDVRQRELEQLGRQLRYYRESADPLSSWLQDAKRRQEQIQA-- 1161
Query: 283 AVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEV--RFITSLNEENKKLIL 340
+ + AR Q R E L + +R G++ + + ++I ++ + +L+
Sbjct: 1162 ----VPIPNSQAAREQL---RQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLVT 1214
Query: 341 RQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERR----KLIEAEKLQRLAEMQRKKEE 396
+ A+K +V E + +E L R + ++ ++ ++E R+ EE
Sbjct: 1215 YKAQLEPVASPAKKPKV--QSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEE 1272
Query: 397 AQIRREEERKASSAAREARAIEQLRRKEERAKAQQE---EAELLAQKLAERLNESEQRRK 453
+ R E+++A R A L ++ + A+A + +AEL AQ+L R+ E RR+
Sbjct: 1273 EE-RLAEQQRAEERERLAEGEAALEKQRQLAEAHAQAKAQAELEAQELQRRMQEEVARRE 1331
Query: 454 IYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIGSITL 513
+++ + LR+S + Q ++ +++ S+ I +
Sbjct: 1332 EAAVNAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEI----------- 1380
Query: 514 QHSMKRRIKRIRQKLMALKYEFLEPPLGGESAGI-GYRVAVGAARAKVGRWLQELQRLR- 571
+++ L+ E E GG + R A A+ + +E +RLR
Sbjct: 1381 -------------RVVRLQLETTERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR 1427
Query: 572 ------QARKEGATSIGLIISEMIKYLEGKDPELQASRQAGL 607
Q +++ + L + + + K LQA + L
Sbjct: 1428 QVQDESQRKRQAEAELALRVKAQAEAAQEKQRALQALEELRL 1469
>PLE1_RAT (P30427) Plectin 1 (PLTN) (PCN)
Length = 4687
Score = 74.3 bits (181), Expect = 2e-12
Identities = 120/498 (24%), Positives = 210/498 (42%), Gaps = 54/498 (10%)
Query: 124 LATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDN-------LRRQMQLPEKDKEK 176
LA T L + A+ ++LK+K E NE+ R ++ L Q + D E+
Sbjct: 1979 LAAISEATRLKTEAE--IALKEK---EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEE 2033
Query: 177 RSTSLGKSMNAWKEKRNW--EDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEK 234
R L K+ + E++ ED L +V + + K+A L +L
Sbjct: 2034 RLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRS 2093
Query: 235 KKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMY 294
+ T K+ AE++ AR ++ +E E R + +R + L E R + L E
Sbjct: 2094 NAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVER 2153
Query: 295 ARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELR-RAE 353
+ + E+R ++ +RA ES++ ++ + K+L +K H ++ R E
Sbjct: 2154 LKAKVEEAR------RLRERAEQESARQLQL----AQEAAQKRLQAEEKAHAFVVQQREE 2203
Query: 354 KLQVIKSKQKEDLAR--EEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREE------ER 405
+LQ +++ L R EA RR EAE+ + AE + + Q+ E E
Sbjct: 2204 ELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEE 2263
Query: 406 KASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQ-IRERAN 464
+A + A+ A E+LR++ E+ A++ +AE A K + + ++ K + EQ +R++A
Sbjct: 2264 QAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQ 2323
Query: 465 LRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIG----SITLQHSMKRR 520
+ +Q LR L + +S + + + + S+ +Q +
Sbjct: 2324 V-EQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGK 2382
Query: 521 IK-RIRQKLMAL-------KYEFLEPPLGGESAGIGYRVAVGAARAKVGRWLQELQRLRQ 572
+K RI + AL FLE E A +VA AAR V QE RLRQ
Sbjct: 2383 LKARIEAENRALILRDKDNTQRFLE-----EEAEKMKQVAEEAARLSVA--AQEAARLRQ 2435
Query: 573 ARKEGATSIGLIISEMIK 590
+E + +M+K
Sbjct: 2436 LAEEDLAQQRALAEKMLK 2453
Score = 61.6 bits (148), Expect = 1e-08
Identities = 94/433 (21%), Positives = 174/433 (39%), Gaps = 68/433 (15%)
Query: 91 DAIRVQKGYIPPESLLTSEVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTE 150
+A R +K + L ++V+ A+ L + +A+ A K L ++KA
Sbjct: 2139 EAARQRKVALEEVERLKAKVEEAR--RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2196
Query: 151 VINEKNPRSTDNL-----------------RRQMQLPEKDKEKRSTSLGKSMNAWKEKRN 193
V+ ++ L RR + E+ +E+ +S +E
Sbjct: 2197 VVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAER 2256
Query: 194 WEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHA-- 251
+ + ++ + RK AE+ + K+K +D + E +K A
Sbjct: 2257 LKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQ 2316
Query: 252 ---RALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFL 308
+ ++ EL T R+Q L+ T + + + E ++ LK E A QRS+ E F
Sbjct: 2317 TLRQKAQVEQELTTLRLQ-LEETDHQKSILDE--ELQRLKA-EVTEAARQRSQVEEELFS 2372
Query: 309 AQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSEL--RRAEKLQVIKSKQ---- 362
+V +E K+ + EN+ LILR K + AEK++ + +
Sbjct: 2373 VRVQM---EELGKLK-----ARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLS 2424
Query: 363 -------------KEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASS 409
+EDLA++ A+ E+ + EK+Q + E R K EA++ ++++ A
Sbjct: 2425 VAAQEAARLRQLAEEDLAQQRALAEK---MLKEKMQAVQEATRLKAEAELLQQQKELAQE 2481
Query: 410 AAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQS 469
AR +A KE+ A+ EE + + L E+E++R++ + ER LR
Sbjct: 2482 QARRLQA-----DKEQMAQQLVEETQGFQRTL-----EAERQRQLEMSAEAERLKLRMAE 2531
Query: 470 SPLLRRSLNKDGQ 482
+ +D Q
Sbjct: 2532 MSRAQARAEEDAQ 2544
Score = 60.5 bits (145), Expect = 3e-08
Identities = 103/491 (20%), Positives = 210/491 (41%), Gaps = 62/491 (12%)
Query: 16 EAFRKIQQERASLKLSNNTEHAMSKCLTSESVGNMNGTHNAKNSRTKSRKHIGSSDANQG 75
EA R+ Q E+A+LK + M K + + + T R + +D +
Sbjct: 2285 EAARRAQAEQAALKQKQAADAEMEKH-KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKS 2343
Query: 76 NLNVKKHNIEGTKPCDAIRVQKGYIPPESLLTSEVDLAKLPSL------ENSSALATAKV 129
L+ + ++ + +A R Q+ + E L + V + +L L EN + + K
Sbjct: 2344 ILDEELQRLKA-EVTEAAR-QRSQVE-EELFSVRVQMEELGKLKARIEAENRALILRDKD 2400
Query: 130 KTH--LGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNA 187
T L A+K+ + ++A + + R QL E+D ++ K +
Sbjct: 2401 NTQRFLEEEAEKMKQVAEEAARLSV------AAQEAARLRQLAEEDLAQQRALAEKML-- 2452
Query: 188 WKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAE 247
KEK + + + L ++ A R++ DK ++ + T ++ E
Sbjct: 2453 -KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQA--DKEQMAQQLVEETQGFQRTLE 2509
Query: 248 EKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSE--SRHE 305
+ R L + +E E +++ + + + +E A R K E + + R+E ++ +
Sbjct: 2510 AERQRQLEMSAEAERLKLRMAEMSRAQAR--AEEDAQRFRKQAEEIGEKLHRTELATQEK 2567
Query: 306 AFLAQVAK----RAGDESSKVNEVRFITSLNEENKKLILRQKL---HGSELRRAEKLQVI 358
L Q + ++ ++ ++ E I L E +KL KL E++ ++ Q++
Sbjct: 2568 VTLVQTLEIQRQQSDQDAERLREA--IAELEREKEKLKQEAKLLQLKSEEMQTVQQEQIL 2625
Query: 359 KSKQ---KEDLAREEAVLERRKLIEAEKLQ----------RLAEMQRKKEEAQIRREEER 405
+ Q K L+ ++++L+R + IE EK + + ++Q +++ Q + E+E+
Sbjct: 2626 QETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEK 2685
Query: 406 KASSAA------REARAIEQLRRKEERAKA----QQEEAELLA---QKLAERLNESEQRR 452
+ A+ R+ A E +RRK+E + +Q++ +LLA Q+L ERL E+
Sbjct: 2686 QELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEH 2745
Query: 453 KIYLEQIRERA 463
+ L E A
Sbjct: 2746 RAALAHSEEIA 2756
Score = 54.3 bits (129), Expect = 2e-06
Identities = 80/352 (22%), Positives = 153/352 (42%), Gaps = 40/352 (11%)
Query: 161 DNLRRQMQLPEKDKEKRSTSLGKSMNAWKEK-----RNWEDILSSPFRVSSRMSYSPSLG 215
D LR ++ E+ ++R + W+E+ W+ +L+ + R LG
Sbjct: 1291 DELRGAQEVGER-LQQRHGERDVEVERWRERVTQLLERWQAVLA---QTDVRQRELEQLG 1346
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKL 275
R+ R D L S + K+ + + +++A R + E +++++R +K+
Sbjct: 1347 RQ-LRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKV 1405
Query: 276 NRVSEW-----HAVRHLKLREGMYARHQRSESRHEAFLAQVAK-RAGDESSKVNEVRFIT 329
++ +A++ +L+ Y +++ A A+ K ++G ES V T
Sbjct: 1406 EECQKFAKQYINAIKDYELQLITY----KAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1461
Query: 330 SLNEENKKLILRQKLHGSELRRAEKLQVI----KSKQKEDLAREEAVLERRKLIEAEKLQ 385
+E K LRR E+ + + +++++E LA EA LE+++ + Q
Sbjct: 1462 RYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1521
Query: 386 RLA-------EMQRKKEEAQIRREE-----ERKASSAAREARAIEQLRRKEERAKAQQEE 433
A E+QR+ +E RREE +++ S E + + Q E +AKAQQ E
Sbjct: 1522 AKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVE 1581
Query: 434 AELLAQKLAERLNESEQRRKIYLEQI-RERANLRDQSSPLLRRSLNKDGQGR 484
A A++ R+ E + ++ LE R+R D+ L R+ + Q R
Sbjct: 1582 A---AERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKR 1630
Score = 53.5 bits (127), Expect = 3e-06
Identities = 65/275 (23%), Positives = 124/275 (44%), Gaps = 13/275 (4%)
Query: 215 GRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQK 274
G+ + VR EK+++ T ++ +R+R+E E Q+ Q ++
Sbjct: 1817 GKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQR-QLLEEE 1875
Query: 275 LNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
L R+ A + R+ + A + + E LA A RA +ES +E E
Sbjct: 1876 LARLQH-EATAATQKRQELEAELAKVRAEMEVLLASKA-RAEEESRSTSEKSKQRLEAEA 1933
Query: 335 NKKLILRQKLHGSELRR-AEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRK 393
+ L ++ + LR AE+ + + +ED AR+ A + + EKL ++E R
Sbjct: 1934 GRFRELAEE--AARLRALAEEARRHRELAEEDAARQRAEADG---VLTEKLAAISEATRL 1988
Query: 394 KEEAQIRREEERKASSAAR---EARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ 450
K EA+I +E+ + R E A ++ R +E+ A+ + + E LAQ +E E+
Sbjct: 1989 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELER 2048
Query: 451 RRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRS 485
++ + + +R+R + ++ L+ S K G++
Sbjct: 2049 QKGLVEDTLRQRRQVEEEIM-ALKASFEKAAAGKA 2082
Score = 50.8 bits (120), Expect = 2e-05
Identities = 56/273 (20%), Positives = 118/273 (42%), Gaps = 17/273 (6%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARA-LRIRSELETERVQKLQRTSQKLNRV 278
++ R++ ++L + + K + E R+ +RI E+ R+Q Q+
Sbjct: 1553 QQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAE 1612
Query: 279 SEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKL 338
E A+R A Q+ +++ EA ++ ++ DES + + +L + +
Sbjct: 1613 DELQALR----ARAEEAEAQKRQAQEEA--ERLRRQVQDESQRKRQAEAELALRVKAEAE 1666
Query: 339 ILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQ 398
R+K L+ ++L++ + + L + EA R+ + E QR AE++ + +
Sbjct: 1667 AAREKQRA--LQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPS 1724
Query: 399 IRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ-------R 451
+ + + E + QLR + ER QQ EAE A++ AER E Q R
Sbjct: 1725 FAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALR 1783
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
++ E++ ++ +L + + ++ + R
Sbjct: 1784 LRLQAEEVAQQKSLAQADAEKQKEEAEREARRR 1816
Score = 45.8 bits (107), Expect = 7e-04
Identities = 74/333 (22%), Positives = 137/333 (40%), Gaps = 28/333 (8%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERV 222
L+R+MQ +E+ + ++A ++KR+ ++ L + S + + ++AER
Sbjct: 1533 LQRRMQEEVTRREEAA------VDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERS 1586
Query: 223 RTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWH 282
R ++ + + + T++ ++ E +ALR R+E + ++ Q +++L R +
Sbjct: 1587 RMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDE 1646
Query: 283 AVR------HLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK 336
+ R L LR A R + R L ++ +A + R++ E
Sbjct: 1647 SQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAE------RWLCQAEAERA 1700
Query: 337 KLI-----LRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQ 391
+ + Q+ EL+ K+ Q E +EE V + EAE R A+ Q
Sbjct: 1701 RQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAE---RRAQQQ 1757
Query: 392 RKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQR 451
+ E A R E ER+ +A +LR + E Q+ A+ A+K E +R
Sbjct: 1758 AEAERA--REEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARR 1815
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
R EQ + L +Q R+ Q R
Sbjct: 1816 RGKAEEQAVRQRELAEQELEKQRQLTEGTAQQR 1848
Score = 45.8 bits (107), Expect = 7e-04
Identities = 63/300 (21%), Positives = 134/300 (44%), Gaps = 32/300 (10%)
Query: 146 KAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWK-----EKRNWEDILSS 200
KA E++ ++ + + RR + DKE+ + L + ++ E++ ++ +
Sbjct: 2466 KAEAELLQQQKELAQEQARRL----QADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAE 2521
Query: 201 PFRVSSRM---SYSPSLGRKSAERVRT--------LHDKLMSPEKKKKTTSDLKKEAEEK 249
R+ RM S + + + A+R R LH ++ ++K L+ + ++
Sbjct: 2522 AERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2581
Query: 250 HARALRIR---SELETER------VQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRS 300
A R+R +ELE E+ + LQ S+++ V + ++ + + + + S
Sbjct: 2582 DQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDS 2641
Query: 301 ESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRA-EKLQVIK 359
+ E F+ Q ++A E +EV L EE ++ + + EL + E+ + +
Sbjct: 2642 LLQRERFIEQ--EKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQ 2699
Query: 360 SKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQ 419
+ +E + R++ L+R + ++ + LAE ++ E R EEE +A+ A E A Q
Sbjct: 2700 REAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATSQ 2759
Score = 42.0 bits (97), Expect = 0.010
Identities = 77/315 (24%), Positives = 133/315 (41%), Gaps = 62/315 (19%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKL 275
++ AER+R ++ + S K++AE + ALR+++E E R + QR Q L
Sbjct: 1633 QEEAERLR----------RQVQDESQRKRQAEAE--LALRVKAEAEAAREK--QRALQAL 1678
Query: 276 N--RVSEWHAVRHLKLREGMYARH--------QRS-----ESRHEAFLAQVAKRAGDESS 320
+ ++ A R L E AR QRS +S+ +F + A+ E +
Sbjct: 1679 DELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQL---ERT 1735
Query: 321 KVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE 380
E +T L EE ++ +Q +E RA + + + ++ L EA+ R + E
Sbjct: 1736 LQEEHVTVTQLREEAERRAQQQ----AEAERARE-EAERELERWQLKANEALRLRLQAEE 1790
Query: 381 AEKLQRLAEM--QRKKEEAQIRREEERKA-SSAAREARAIEQLRRK---------EERAK 428
+ + LA+ +++KEEA+ KA A R+ EQ K ++R
Sbjct: 1791 VAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLA 1850
Query: 429 AQQE-------------EAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
A+QE + +LL ++LA +E+ + E E A +R + LL
Sbjct: 1851 AEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLAS 1910
Query: 476 SLNKDGQGRSTPNNS 490
+ + RST S
Sbjct: 1911 KARAEEESRSTSEKS 1925
Score = 41.6 bits (96), Expect = 0.013
Identities = 81/405 (20%), Positives = 162/405 (40%), Gaps = 37/405 (9%)
Query: 109 EVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQ 168
E+ L KL + + SA+ K+KT +SL ++ T+ E ++L+
Sbjct: 1208 ELTLGKLEQVRSLSAIYLEKLKT---------ISLVIRS-TQGAEEVLKTHEEHLKEAQA 1257
Query: 169 LPEKDKEKRSTSLG-KSMNAWKEKRN-----WEDILSSPFRVSSRMSYSPSLGRKSAERV 222
+P +E T K + A E + D L V R+ ER
Sbjct: 1258 VPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERW 1317
Query: 223 RTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWH 282
R +L+ + +D+++ E+ R LR E LQ + ++
Sbjct: 1318 RERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQA-- 1375
Query: 283 AVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEV--RFITSLNEENKKLIL 340
+ + AR Q R E L + +R G++ + + ++I ++ + +LI
Sbjct: 1376 ----VPIANSQAAREQL---RQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLIT 1428
Query: 341 RQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERR----KLIEAEKLQRLAEMQRKKEE 396
+ A+K +V E + +E L R + ++ ++ ++E R+ EE
Sbjct: 1429 YKAQLEPVASPAKKPKV--QSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEE 1486
Query: 397 AQIRREEERKASSAAREARAIEQLRRKEERAKAQQE---EAELLAQKLAERLNESEQRRK 453
+ R E+++A R A L ++ + A+A + +AEL A++L R+ E RR+
Sbjct: 1487 EE-RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRRE 1545
Query: 454 IYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNI 498
+++ + LR+S + Q ++ +++ S+ I
Sbjct: 1546 EAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRI 1590
>INCE_CHICK (P53352) Inner centromere protein
Length = 877
Score = 74.3 bits (181), Expect = 2e-12
Identities = 60/228 (26%), Positives = 115/228 (50%), Gaps = 13/228 (5%)
Query: 244 KEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESR 303
KE E + +ALR + E E R QK++ +K R E R +LR+ + AR +R+E
Sbjct: 503 KEKERQKLQALRKKEEAEQLRKQKVEE--EKKRRQEEAKLRREERLRKVLQAR-ERAEQL 559
Query: 304 HEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSK-- 361
E ++ ++ K + R E+ KK +K+ +E RR + + K K
Sbjct: 560 EEERKRRIEQKLALFDEKTEKAREERLAEEKIKKRAAAKKMEEAEARRRQDEEARKQKAL 619
Query: 362 -QKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQL 420
Q+E+ R + +++++K E E+ +++AE ++ ++E + + ER+ + R E+
Sbjct: 620 QQEEEERRHKELMQKKKEEEQERARKIAEQRQAEQEREKQLAAEREQERKKEQERKKEEE 679
Query: 421 RRKEERAKAQQEEA-----ELLAQK--LAERLNESEQRRKIYLEQIRE 461
R + E+ + QQE+A E+LA K L + + + E+ ++ E R+
Sbjct: 680 RIQAEKQREQQEKAARLQKEVLAAKEQLQKEMEKKEKEEQLLAEMKRQ 727
Score = 70.9 bits (172), Expect = 2e-11
Identities = 83/316 (26%), Positives = 149/316 (46%), Gaps = 38/316 (12%)
Query: 204 VSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETE 263
+ S + Y+ L E+ R KL + KK++ K++ EE+ R + E +
Sbjct: 488 IKSFIKYNTPLQHDPKEKER---QKLQALRKKEEAEQLRKQKVEEEKKRR---QEEAKLR 541
Query: 264 RVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQ--VAKRAGDESSK 321
R ++L++ Q R + R ++ + + +++E E LA+ + KRA + +
Sbjct: 542 REERLRKVLQARERAEQLEEERKRRIEQKLALFDEKTEKAREERLAEEKIKKRAAAKKME 601
Query: 322 VNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLARE-----EAVLERR 376
E R E K+ L+Q+ E RR ++L K +++++ AR+ +A ER
Sbjct: 602 EAEARRRQD-EEARKQKALQQE---EEERRHKELMQKKKEEEQERARKIAEQRQAEQERE 657
Query: 377 KLIEAEKLQ-RLAEMQRKKEEAQIR----REEERKASSAAREARAI-EQLRR------KE 424
K + AE+ Q R E +RKKEE +I+ RE++ KA+ +E A EQL++ KE
Sbjct: 658 KQLAAEREQERKKEQERKKEEERIQAEKQREQQEKAARLQKEVLAAKEQLQKEMEKKEKE 717
Query: 425 ERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQ-G 483
E+ A+ + E +KL E E + + + + + N +S + +KD +
Sbjct: 718 EQLLAEMKRQEQEQKKLPE---EQKAKDVAQTQHLENKENSPACNSYQMTPQYHKDPKPP 774
Query: 484 RSTPNN-----SSDDS 494
+ PNN +SDDS
Sbjct: 775 KINPNNYGMDLNSDDS 790
>YAFA_SCHPO (Q09863) Hypothetical protein C29E6.10c in chromosome I
Length = 1085
Score = 71.6 bits (174), Expect = 1e-11
Identities = 48/174 (27%), Positives = 94/174 (53%), Gaps = 5/174 (2%)
Query: 307 FLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQ--KLHGSELRRAEKLQVIKSKQKE 364
F +V + ++ ++ + + + + EENK+ R+ K+ E +R +K Q+ +K++E
Sbjct: 552 FEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKKQLKLAKEEE 611
Query: 365 DLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRR-K 423
RE L + +A + +R E ++K+EE +++RE+E+K R+ R +Q ++ +
Sbjct: 612 RQRREAERLAEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQELERQKREEKQKQKER 671
Query: 424 EERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSL 477
E++ K QQ+EA+ +RL E E++R LE+ + R L + RR L
Sbjct: 672 EKKLKKQQQEADREKMAREQRLREEEEKR--ILEERKRREKLDKEEEERRRREL 723
Score = 52.8 bits (125), Expect = 6e-06
Identities = 53/210 (25%), Positives = 102/210 (48%), Gaps = 37/210 (17%)
Query: 243 KKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSES 302
+K A+++ A+ L E+E E +K +R +K+ + + K ++ A+ + +
Sbjct: 562 EKVAQQRQAKLLE---EIEEENKRKQERELKKIREKEK----KRDKKKQLKLAKEEERQR 614
Query: 303 RHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQ 362
R LA+ A + E+ + E R E ++L Q+ EL R ++ + K KQ
Sbjct: 615 REAERLAEQAAQKALEAKRQEEAR----KKREEQRLKREQEKKQQELERQKREE--KQKQ 668
Query: 363 KEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRR 422
KE RE+ + ++++ + EK+ R E ++R EEE+ R +E+ +R
Sbjct: 669 KE---REKKLKKQQQEADREKMAR---------EQRLREEEEK---------RILEERKR 707
Query: 423 KEERAKAQQEEAELLAQKLAERLNESEQRR 452
+E K +EE E ++L E+ +E ++RR
Sbjct: 708 RE---KLDKEEEERRRRELLEKESEEKERR 734
Score = 51.6 bits (122), Expect = 1e-05
Identities = 59/296 (19%), Positives = 130/296 (42%), Gaps = 21/296 (7%)
Query: 196 DILSSPFRVSS-RMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARAL 254
D+++ R+ R + R +RV + + ++ +++ K ++++E + K R L
Sbjct: 529 DLMTDEQRMEEGRRMFQIFAARLFEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQEREL 588
Query: 255 RIRSELETERVQKLQ--------RTSQKLNRVSEWHAVRHLKLREGMYARHQRSESR--- 303
+ E E +R +K Q R ++ R++E A + L+ + AR +R E R
Sbjct: 589 KKIREKEKKRDKKKQLKLAKEEERQRREAERLAEQAAQKALEAKRQEEARKKREEQRLKR 648
Query: 304 -HEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKS-K 361
E ++ ++ +E K E L ++ ++ + LR E+ ++++ K
Sbjct: 649 EQEKKQQELERQKREEKQKQKERE--KKLKKQQQEADREKMAREQRLREEEEKRILEERK 706
Query: 362 QKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLR 421
++E L +EE RR+L+E E ++ ++ K A + ++ S + +
Sbjct: 707 RREKLDKEEEERRRRELLEKESEEKERRLREAKIAAFFAPNQTKEGSDGCTTSSQLGLFE 766
Query: 422 RKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSL 477
+K + + + L+ L + + + ++ I L+ + R+ SS LL SL
Sbjct: 767 KKGDLV----NDEDKLSSHLLDSVPNALRQAPIGLKNTNNLSE-RNASSNLLNSSL 817
Score = 51.2 bits (121), Expect = 2e-05
Identities = 57/263 (21%), Positives = 117/263 (43%), Gaps = 29/263 (11%)
Query: 223 RTLHDKLMSPEKKKKTTSDLKKEAEEKHA---------RALRIRSELETERVQKLQRTSQ 273
+TL D SP+ + +A+EK++ +L ++ + T L+ +
Sbjct: 419 QTLEDTSHSPQTQPPFQPPYPSKADEKNSYHSDLYNFGSSLTVKGGILTVADDLLKNDGK 478
Query: 274 KLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLN- 332
K + E A R ++ + + E + +E +E+ +T
Sbjct: 479 KFIEMMEQLAERRMQREDN--SNFHEPELYESGLEYDEDEEEDEEDVDEDELDLMTDEQR 536
Query: 333 -EENKKL--ILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAE 389
EE +++ I +L + +A + +V + +Q + L E +R++ E +K++ +
Sbjct: 537 MEEGRRMFQIFAARLFEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEK 596
Query: 390 MQRKKEEAQIRREEERKASSAAR----------EARAIEQLRRK--EERAKAQQE--EAE 435
+ KK++ ++ +EEER+ A R EA+ E+ R+K E+R K +QE + E
Sbjct: 597 KRDKKKQLKLAKEEERQRREAERLAEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQE 656
Query: 436 LLAQKLAERLNESEQRRKIYLEQ 458
L QK E+ + E+ +K+ +Q
Sbjct: 657 LERQKREEKQKQKEREKKLKKQQ 679
Score = 38.9 bits (89), Expect = 0.086
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 16/195 (8%)
Query: 138 DKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDI 197
+K+ + E I E+N R + ++++ EK ++K+ L + +++R E +
Sbjct: 562 EKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKK-QLKLAKEEERQRREAERL 620
Query: 198 LSSPFRVSSRMSYSPSLGRKSAER--VRTLHDKLMSPEKKKKTTSDLKKEAE-------- 247
+ + +K E+ R K E++K+ +KE E
Sbjct: 621 AEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQELERQKREEKQKQKEREKKLKKQQQ 680
Query: 248 ----EKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESR 303
EK AR R+R E E +R+ + ++ +KL++ E R L +E + E++
Sbjct: 681 EADREKMAREQRLREE-EEKRILEERKRREKLDKEEEERRRRELLEKESEEKERRLREAK 739
Query: 304 HEAFLAQVAKRAGDE 318
AF A + G +
Sbjct: 740 IAAFFAPNQTKEGSD 754
>TRHY_SHEEP (P22793) Trichohyalin
Length = 1549
Score = 71.6 bits (174), Expect = 1e-11
Identities = 68/310 (21%), Positives = 141/310 (44%), Gaps = 16/310 (5%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
EK LR + QL +++EKR +++R + + + ++
Sbjct: 477 EKQYLEKVELREEEQLQRQEREKR-----------RQERERQYLEKVELQEEEQLQREER 525
Query: 214 LGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQ 273
R+ ER R +K+ E+++ + +K +E+ + L E E++Q+ +R +
Sbjct: 526 EKRRQ-ERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKR 584
Query: 274 KLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNE 333
+ R ++ + ++L+E + Q E R + Q ++ + + + + +
Sbjct: 585 RQEREKQY--LEKVELQEEEQLQRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQ 642
Query: 334 ENKKLILRQKLHGSELRRAEKLQVIKS-KQKEDLAREEAVLERRKLIEAEKLQRLAEMQR 392
E ++ L ++L E R E+ Q+++ ++K RE LE+ +L E E+LQR +R
Sbjct: 643 ERERQYLEKELQRQEERLQEEEQLLREEREKRRQERERQYLEKVELQEEEQLQREEREKR 702
Query: 393 KKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRR 452
++E + E+E R R EQL+R++ + Q E + L ++L + + QR
Sbjct: 703 RQERERQYLEKEELQRQEERLQREKEQLQREDREKRRQVRERKYLEEELQQE-EDRLQRE 761
Query: 453 KIYLEQIRER 462
K L + RE+
Sbjct: 762 KQLLREDREK 771
Score = 69.7 bits (169), Expect = 5e-11
Identities = 88/393 (22%), Positives = 166/393 (41%), Gaps = 61/393 (15%)
Query: 139 KLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKR------ 192
+L S D +V + + + + R++ +L E+ +E++ + +S+ + ++
Sbjct: 300 QLESEADARQRKVYSRPHRQEQQSRRQEQELLERQQEQQISEEVQSLQEDQGRQRLKQEQ 359
Query: 193 ----NWEDILSSPFRVSSRMSYSPSLGRKSA---ERVRTLHDKLMSPEKKKKTTSDLKK- 244
NW L + Y+ R+ E++R +KL +++++ ++
Sbjct: 360 RYDQNWRWQLEEESQRRRYTLYAKPAQREQVREEEQLRLKEEKLQREKRRQERERQYREV 419
Query: 245 EAEEKHARALRIRSEL---ETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSE 301
E + + R R +L E E+ ++ +R Q L +V W L+ E R +R +
Sbjct: 420 ELQREEERLQREEEQLQREEREKRRRQEREKQYLEKVELWEE-EQLQREE----REKRRQ 474
Query: 302 SRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSK 361
R + +L +V R ++ + E+ ++ RQ L EL+ E+LQ + +
Sbjct: 475 EREKQYLEKVELREEEQLQRQER--------EKRRQERERQYLEKVELQEEEQLQR-EER 525
Query: 362 QKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKE--------------------EAQIRR 401
+K RE LE+ +L E E+LQR +R++E E Q RR
Sbjct: 526 EKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRR 585
Query: 402 EEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQ---------KLAERLNESEQRR 452
+E K E + EQL+R+E + Q+ E + L + + ER ++R
Sbjct: 586 QEREKQYLEKVELQEEEQLQRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERE 645
Query: 453 KIYLEQIRERANLR-DQSSPLLRRSLNKDGQGR 484
+ YLE+ +R R + LLR K Q R
Sbjct: 646 RQYLEKELQRQEERLQEEEQLLREEREKRRQER 678
Score = 68.2 bits (165), Expect = 1e-10
Identities = 77/275 (28%), Positives = 130/275 (47%), Gaps = 33/275 (12%)
Query: 233 EKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRH----LK 288
++K + + L +E EE+ R R R E E Q LQ ++L R R L+
Sbjct: 1251 DRKFREEAQLLQEREEQLRRQERDRKFREEE--QLLQEREEQLRRQERDRKFREEEQLLQ 1308
Query: 289 LREGMYARHQRSES-RHEAFLAQVAK---RAGDESSKVNEVRFITSLNEENKKLILRQKL 344
RE R +R R E L + ++ R + K +E + L E ++ + RQ+L
Sbjct: 1309 EREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHEKEHL--LREREEQQLRRQEL 1366
Query: 345 HG-----SELRRAEKLQVIKSKQKED--LAREEAVLERRKLIEAEKLQRLAEMQRK--KE 395
G +LRRAE+ + + +++ D EE L+R + E+ +R+ E RK ++
Sbjct: 1367 EGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEEQSLQRER---EEEKRRVQEQDRKFLEQ 1423
Query: 396 EAQIRREEE---RKASSAAREARAIEQLRRKEERAKAQQE---EAELLAQKLAERLNESE 449
E Q+ REE+ R+ ++ RA EQ R+E+R + +QE E + Q+ + E E
Sbjct: 1424 EEQLHREEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEEQRRRQERERKFREEE 1483
Query: 450 QRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
Q R+ E+ + R Q S RR + ++ +GR
Sbjct: 1484 QLRRQQQEEQKRRQERDVQQS---RRQVWEEDKGR 1515
Score = 68.2 bits (165), Expect = 1e-10
Identities = 78/336 (23%), Positives = 147/336 (43%), Gaps = 53/336 (15%)
Query: 152 INEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYS 211
+ E+ + D L+R+ QL +D+EKR + +E+ E
Sbjct: 747 LEEELQQEEDRLQREKQLLREDREKRQYLEKVELQREEEQLQREK--------------- 791
Query: 212 PSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRT 271
R+ ER + L E+ + L++E EK R + +LE E +Q+L R
Sbjct: 792 ---RRQERERQYREEELLREEERLHRKEQQLQREECEKRRRQ-ELERQLEEEELQRLDRK 847
Query: 272 SQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRF---I 328
Q + + VR+ + +Y++H+ ++ + + S V E +F +
Sbjct: 848 RQFRDDDQHQNEVRNSR----VYSKHRENKEKSRQL----------DDSWVRESQFQQDL 893
Query: 329 TSLNEENKKLILRQKLHGSELRR-----AEKLQVIKSKQKEDLAREEAVLERRKLIEAEK 383
L +E ++ R++ S +R AE+L + + +QKE R+ E +L++ ++
Sbjct: 894 RPLQDEQEEKREREQEWRSRQKRDSQFPAEQL-LEREQQKETERRDRKFREEEQLLKGQR 952
Query: 384 LQRLAEMQR----KKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQ 439
+++ ++ ++EE Q+RR E + R+ + E+L R+E K ++EE L Q
Sbjct: 953 EEKIRYLEEDRKFREEEQQLRRLEREQQLRQERDRKFREELSRQERDRKFREEEQ--LLQ 1010
Query: 440 KLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
+ E+L E+ RK RE L + LRR
Sbjct: 1011 EREEQLRRQERDRK-----FREEEQLLQEREEQLRR 1041
Score = 67.8 bits (164), Expect = 2e-10
Identities = 68/264 (25%), Positives = 130/264 (48%), Gaps = 12/264 (4%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSD--LKKEAEEKHARALRIRSELETERVQK-LQRTS 272
R+ + ++ ++L E+ +K + L +E EE+ R R R E E++ K +
Sbjct: 1278 REEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLKESEEQL 1337
Query: 273 QKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLN 332
++ R ++H HL LRE + +R E + +RA E + + +
Sbjct: 1338 RRQERDRKFHEKEHL-LREREEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFL 1396
Query: 333 EENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAV-LERRKLIEAE---KLQRLA 388
EE + L Q+ E RR ++ +Q+E L REE L RR+ ++ + + Q
Sbjct: 1397 EEEQSL---QREREEEKRRVQEQDRKFLEQEEQLHREEQEELRRRQQLDQQYRAEEQFAR 1453
Query: 389 EMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNES 448
E +R+++E ++R+EE+R+ R+ R EQLRR+++ + +++E + + Q + E
Sbjct: 1454 EEKRRRQEQELRQEEQRRRQERERKFREEEQLRRQQQEEQKRRQERD-VQQSRRQVWEED 1512
Query: 449 EQRRKIYLEQIRERANLRDQSSPL 472
+ RR++ R+ A+ +SSPL
Sbjct: 1513 KGRRQVLEAGKRQFASAPVRSSPL 1536
Score = 67.0 bits (162), Expect = 3e-10
Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 22/265 (8%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKL 275
RK E + L ++ E+ ++ D K EE+ R L +L ER +K R Q L
Sbjct: 1046 RKFREEEQLLQER---EEQLRRQERDRKFREEEQQLRLLEREQQLRQERNRKF-REEQLL 1101
Query: 276 NRVSEWHAVRHLKLREGMYARHQRSESR--HEAFLAQVAK---RAGDESSKVNEVRFITS 330
E L+L+EG Q+ + + E L Q + R + K E I
Sbjct: 1102 REREE-----QLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRRQERDRKFREEAQILK 1156
Query: 331 LNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEM 390
EE + R + E + ++ + ++ +++E R+E +R+ E + LQ ++
Sbjct: 1157 EREEQLRRQERDRKFREEEQLLQEREELRRQEREPQLRQER--DRKFREEEQLLQEREKL 1214
Query: 391 QRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ 450
+R++ E Q+R+E +RK + + E+ R++ER + +EEA+LL Q+ E+L E+
Sbjct: 1215 RRQEREPQLRQERDRKFHEEEQLLQEREEQLRRQERDRKFREEAQLL-QEREEQLRRQER 1273
Query: 451 RRKIYLEQIRERANLRDQSSPLLRR 475
RK RE L + LRR
Sbjct: 1274 DRK-----FREEEQLLQEREEQLRR 1293
Score = 63.9 bits (154), Expect = 2e-09
Identities = 77/338 (22%), Positives = 151/338 (43%), Gaps = 42/338 (12%)
Query: 158 RSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRK 217
R + RR+ +L K++E+R L + +E+ E+I +SR + L +
Sbjct: 251 RLLEQERREQELRRKEQERREQQLRQE----QEEATQEEISERGESRTSRCQWQ--LESE 304
Query: 218 SAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNR 277
+ R R ++ + E++ + E +++ + ++S E + Q+L++ Q+ ++
Sbjct: 305 ADARQRKVYSRPHRQEQQSRRQEQELLERQQEQQISEEVQSLQEDQGRQRLKQ-EQRYDQ 363
Query: 278 VSEWHAVRHLKLRE-GMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK 336
W + R +YA+ + E E +E ++ E + L E +
Sbjct: 364 NWRWQLEEESQRRRYTLYAKPAQREQVRE-----------EEQLRLKEEK----LQREKR 408
Query: 337 KLILRQKLHGSELRRAE-KLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLA---EMQR 392
+ ++ EL+R E +LQ +++E L REE RR+ E + L+++ E Q
Sbjct: 409 RQERERQYREVELQREEERLQ----REEEQLQREEREKRRRQEREKQYLEKVELWEEEQL 464
Query: 393 KKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQ---------KLAE 443
++EE + RR+E K E R EQL+R+E + Q+ E + L + + E
Sbjct: 465 QREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREE 524
Query: 444 RLNESEQRRKIYLE--QIRERANLRDQSSPLLRRSLNK 479
R ++R + YLE +++E L+ Q R+ K
Sbjct: 525 REKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREK 562
Score = 61.2 bits (147), Expect = 2e-08
Identities = 74/292 (25%), Positives = 125/292 (42%), Gaps = 41/292 (14%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSD--LKKEAEEKHARALRIRS-----ELETERVQKLQRTS 272
ER R ++L E+ +K + L +E EE+ R R R +L ER ++L+R
Sbjct: 984 ERDRKFREELSRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQE 1043
Query: 273 Q--KLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITS 330
+ K + R +LR R R E + L + + + + K E + +
Sbjct: 1044 RDRKFREEEQLLQEREEQLRRQERDRKFREEEQQLRLLEREQQLRQERNRKFREEQLLRE 1103
Query: 331 LNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREE----------AVLER----- 375
E+ + +L R+ + + + +++E L R+E + ER
Sbjct: 1104 REEQLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRRQERDRKFREEAQILKEREEQLR 1163
Query: 376 -----RKLIEAEK-LQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKA 429
RK E E+ LQ E++R++ E Q+R+E +RK + + E+LRR+E +
Sbjct: 1164 RQERDRKFREEEQLLQEREELRRQEREPQLRQERDRKFREEEQLLQEREKLRRQEREPQL 1223
Query: 430 QQE------EAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
+QE E E L Q+ E+L E+ RK RE A L + LRR
Sbjct: 1224 RQERDRKFHEEEQLLQEREEQLRRQERDRK-----FREEAQLLQEREEQLRR 1270
Score = 60.1 bits (144), Expect = 4e-08
Identities = 87/347 (25%), Positives = 153/347 (44%), Gaps = 30/347 (8%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPF---RVSSRMSYSPSLGRKSA 219
L+ + QL +++EKR K E + E + R Y + +
Sbjct: 542 LQEEEQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVELQEE 601
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVS 279
E+++ + E++++ ++ + EE+ R R + E ER Q ++L R
Sbjct: 602 EQLQRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERER----QYLEKELQRQE 657
Query: 280 EWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLI 339
E LRE R +R + R +L +V + +E E R E+ ++
Sbjct: 658 ERLQEEEQLLRE---EREKRRQERERQYLEKVELQ--EEEQLQREER------EKRRQER 706
Query: 340 LRQKLHGSELRRAE-KLQVIKSK-QKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEA 397
RQ L EL+R E +LQ K + Q+ED + V ER+ L E+LQ+ E R + E
Sbjct: 707 ERQYLEKEELQRQEERLQREKEQLQREDREKRRQVRERKYL--EEELQQ--EEDRLQREK 762
Query: 398 QIRRE--EERKASSAAREARAIEQLRRKEERAKAQQE--EAELLAQKLAERLNESEQRRK 453
Q+ RE E+R+ R EQL+R++ R + +++ E ELL ++ ERL+ EQ+ +
Sbjct: 763 QLLREDREKRQYLEKVELQREEEQLQREKRRQERERQYREEELLREE--ERLHRKEQQLQ 820
Query: 454 IYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIAS 500
+ R R L Q + L++ Q R + ++ + + S
Sbjct: 821 REECEKRRRQELERQLEEEELQRLDRKRQFRDDDQHQNEVRNSRVYS 867
Score = 59.3 bits (142), Expect = 6e-08
Identities = 78/322 (24%), Positives = 145/322 (44%), Gaps = 45/322 (13%)
Query: 193 NWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHAR 252
++ + L+ F+V++ Y+ LG+ S L++K E+K D ++E + +
Sbjct: 70 DFHEFLAIVFKVAAACYYA--LGQASG-----LNEKEAKCERKGNPLQDRRREDQRRFEP 122
Query: 253 ALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLR-EGMYARHQRSESRHEAFLAQV 311
R +LE R+++ Q+L ++E +R ++R E R ++ E E L Q
Sbjct: 123 QDR---QLEERRLKR-----QELEELAEEEELREKQVRREQRLQRREQEEYGGEEELQQR 174
Query: 312 AKRAGDESSKVNEVRFITSLNEENKKL-ILRQKLHGSELR-RAEKLQVIKSKQKE----- 364
K E E RF E ++L + +Q+ ELR R E++Q+ K + +E
Sbjct: 175 PKGRELEELLNREQRFERQEQRERQRLQVEQQQRQRGELRERQEEVQLQKRETQELQRER 234
Query: 365 -----DLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREE---------ERKASSA 410
L +++ LE R L + + Q L ++++ E Q+R+E+ ER S
Sbjct: 235 LEEEQQLQKQKRGLEERLLEQERREQELRRKEQERREQQLRQEQEEATQEEISERGESRT 294
Query: 411 AR-----EARAIEQLRRKEERAKAQQEEAELLAQKLAERLNE---SEQRRKIYLEQIRER 462
+R E+ A + R+ R Q++++ Q+L ER E SE+ + + +Q R+R
Sbjct: 295 SRCQWQLESEADARQRKVYSRPHRQEQQSRRQEQELLERQQEQQISEEVQSLQEDQGRQR 354
Query: 463 ANLRDQSSPLLRRSLNKDGQGR 484
+ R L ++ Q R
Sbjct: 355 LKQEQRYDQNWRWQLEEESQRR 376
Score = 58.5 bits (140), Expect = 1e-07
Identities = 69/288 (23%), Positives = 133/288 (45%), Gaps = 46/288 (15%)
Query: 227 DKLMSPEKKKKTTSDLKKEAEE----KHARALRIRSELETERVQKLQRTSQKLNRVSEWH 282
++L+ E++K+T +K EE K R +IR E + ++ ++ ++L R +
Sbjct: 923 EQLLEREQQKETERRDRKFREEEQLLKGQREEKIRYLEEDRKFREEEQQLRRLEREQQLR 982
Query: 283 AVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQ 342
R K RE + + + + R E L Q + + + R EE + L R+
Sbjct: 983 QERDRKFREELSRQERDRKFREEEQLLQEREEQLRRQERDRKFR------EEEQLLQERE 1036
Query: 343 KLHGSELRRAEKLQVIKSKQ------KEDLAREE------------AVLERRKLIEAEKL 384
+ +LRR E+ + + ++ +E L R+E +LER + + E+
Sbjct: 1037 E----QLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQQLRLLEREQQLRQERN 1092
Query: 385 QRLAEMQRKKE----------EAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEA 434
++ E Q +E E Q+R++ +RK + + E+ R++ER + +EEA
Sbjct: 1093 RKFREEQLLREREEQLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRRQERDRKFREEA 1152
Query: 435 ELLAQKLAERLNESEQRRKIYLEQ--IRERANLRDQS-SPLLRRSLNK 479
++L ++ E+L E+ RK E+ ++ER LR Q P LR+ ++
Sbjct: 1153 QILKER-EEQLRRQERDRKFREEEQLLQEREELRRQEREPQLRQERDR 1199
Score = 56.6 bits (135), Expect = 4e-07
Identities = 74/272 (27%), Positives = 121/272 (44%), Gaps = 38/272 (13%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVS 279
ER R ++ + E++++ L+ + E R R R E E Q LQ ++L R
Sbjct: 1090 ERNRKFREEQLLREREEQ----LRLQEGEPQLRQKRDRKFHEEE--QLLQEREEQLRRQE 1143
Query: 280 EWHAVRH----LKLREGMYARHQRSES-RHEAFLAQVAK--RAGDESSKVNEVRFITSLN 332
R LK RE R +R R E L Q + R + ++ + R
Sbjct: 1144 RDRKFREEAQILKEREEQLRRQERDRKFREEEQLLQEREELRRQEREPQLRQERD-RKFR 1202
Query: 333 EENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQR 392
EE + L R+KL RR E+ ++ ++ EE +L+ R+ E+L+R ++
Sbjct: 1203 EEEQLLQEREKL-----RRQEREPQLRQERDRKFHEEEQLLQERE----EQLRRQERDRK 1253
Query: 393 KKEEAQI---------RREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAE 443
+EEAQ+ R+E +RK + + E+ R++ER + +EE +LL Q+ E
Sbjct: 1254 FREEAQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLL-QEREE 1312
Query: 444 RLNESEQRRKIYLEQIRERANLRDQSSPLLRR 475
+L E+ RK RE L +S LRR
Sbjct: 1313 QLRRQERDRK-----FREEEQLLKESEEQLRR 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 73/283 (25%), Positives = 122/283 (42%), Gaps = 30/283 (10%)
Query: 228 KLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERV----QKLQRTSQ----KLNRVS 279
K E+ + +L+++ E R R R E E++ +KL+R + + R
Sbjct: 1170 KFREEEQLLQEREELRRQEREPQLRQERDRKFREEEQLLQEREKLRRQEREPQLRQERDR 1229
Query: 280 EWHAVRHL-KLREGMYARHQRSES-RHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKK 337
++H L + RE R +R R EA L Q + + + R L +E ++
Sbjct: 1230 KFHEEEQLLQEREEQLRRQERDRKFREEAQLLQEREEQLRRQERDRKFREEEQLLQEREE 1289
Query: 338 LILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLI-EAEKLQRLAEMQRK--- 393
+ RQ+ + R E+L + +Q R+ E +L+ E+E+ R E RK
Sbjct: 1290 QLRRQE-RDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHE 1348
Query: 394 -------KEEAQIRREEERKASSAAREARAI----EQLRRKEERAKAQQEEAELLAQKLA 442
+EE Q+RR+E S + R EQ R+++ K +EE L ++
Sbjct: 1349 KEHLLREREEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEEQSLQREREE 1408
Query: 443 ERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRS 485
E+ EQ RK +LEQ E+ + +Q LRR D Q R+
Sbjct: 1409 EKRRVQEQDRK-FLEQ-EEQLHREEQEE--LRRRQQLDQQYRA 1447
Score = 54.3 bits (129), Expect = 2e-06
Identities = 83/339 (24%), Positives = 141/339 (41%), Gaps = 38/339 (11%)
Query: 164 RRQMQLPEKDKEKRSTSL------GKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRK 217
R++ QL ++ EKR + + KR + D V + YS R+
Sbjct: 814 RKEQQLQREECEKRRRQELERQLEEEELQRLDRKRQFRDDDQHQNEVRNSRVYSKH--RE 871
Query: 218 SAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSE------------LETERV 265
+ E+ R L D + + ++ L+ E EEK R RS LE E+
Sbjct: 872 NKEKSRQLDDSWVRESQFQQDLRPLQDEQEEKREREQEWRSRQKRDSQFPAEQLLEREQQ 931
Query: 266 QKLQRTSQKLNRVSEW-HAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNE 324
++ +R +K + R K+R Y R E L ++ + + +
Sbjct: 932 KETERRDRKFREEEQLLKGQREEKIR---YLEEDRKFREEEQQLRRLEREQQLRQERDRK 988
Query: 325 VRFITSLNEENKKLILRQKL---HGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEA 381
R S E ++K ++L +LRR E+ + K +++E L +E RR+ E
Sbjct: 989 FREELSRQERDRKFREEEQLLQEREEQLRRQERDR--KFREEEQLLQEREEQLRRQ--ER 1044
Query: 382 EKLQRLAEMQRKKEEAQIRREE-ERKASSAAREARAIE---QLRRKEERAKAQQEEAELL 437
++ R E ++ E Q+RR+E +RK ++ R +E QLR +ER + +EE L
Sbjct: 1045 DRKFREEEQLLQEREEQLRRQERDRKFREEEQQLRLLEREQQLR--QERNRKFREEQLLR 1102
Query: 438 AQKLAERLNESE-QRRKIYLEQIRERANLRDQSSPLLRR 475
++ RL E E Q R+ + E L + LRR
Sbjct: 1103 EREEQLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRR 1141
Score = 53.9 bits (128), Expect = 3e-06
Identities = 74/256 (28%), Positives = 113/256 (43%), Gaps = 33/256 (12%)
Query: 233 EKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREG 292
++K L +E EE+ R R R E Q L+ ++L R R K RE
Sbjct: 1122 DRKFHEEEQLLQEREEQLRRQERDRKF--REEAQILKEREEQLRRQE-----RDRKFREE 1174
Query: 293 MYARHQRSESRH---EAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQ----KLH 345
+R E R E L Q R E ++ + R L + ++ LRQ K H
Sbjct: 1175 EQLLQEREELRRQEREPQLRQERDRKFREEEQLLQER--EKLRRQEREPQLRQERDRKFH 1232
Query: 346 GSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRK-KEEAQI--RRE 402
E E+ + ++ ++++ REEA L L E E+ R E RK +EE Q+ RE
Sbjct: 1233 EEEQLLQEREEQLRRQERDRKFREEAQL----LQEREEQLRRQERDRKFREEEQLLQERE 1288
Query: 403 EERKASSAAREARAIEQL-RRKEERAKAQQ-----EEAELLAQKLAERLNESEQRRKI-- 454
E+ + R+ R EQL + +EE+ + Q+ E E L ++ E+L E+ RK
Sbjct: 1289 EQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHE 1348
Query: 455 --YLEQIRERANLRDQ 468
+L + RE LR Q
Sbjct: 1349 KEHLLREREEQQLRRQ 1364
Score = 53.5 bits (127), Expect = 3e-06
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 27/264 (10%)
Query: 233 EKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHL-KLRE 291
EK + D K EE+ R L +L ER +K + + R ++ L + RE
Sbjct: 954 EKIRYLEEDRKFREEEQQLRRLEREQQLRQERDRKFREELSRQERDRKFREEEQLLQERE 1013
Query: 292 GMYARHQRSES-RHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKL------ 344
R +R R E L Q + + + R L +E ++ + RQ+
Sbjct: 1014 EQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFRE 1073
Query: 345 HGSELRRAEKLQVIKSKQKEDLAREEAVLERR---KLIEAEKLQRLAEMQRKKEEAQI-- 399
+LR E+ Q ++ ++ E+ + ER +L E E R ++ EE Q+
Sbjct: 1074 EEQQLRLLEREQQLRQERNRKFREEQLLREREEQLRLQEGEPQLRQKRDRKFHEEEQLLQ 1133
Query: 400 RREEERKASSAAREAR--------AIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQR 451
REE+ + R+ R EQLRR+E K ++EE Q L ER Q
Sbjct: 1134 EREEQLRRQERDRKFREEAQILKEREEQLRRQERDRKFREEE-----QLLQEREELRRQE 1188
Query: 452 RKIYLEQIRERANLRDQSSPLLRR 475
R+ L Q R+R R++ L R
Sbjct: 1189 REPQLRQERDR-KFREEEQLLQER 1211
Score = 45.1 bits (105), Expect = 0.001
Identities = 55/250 (22%), Positives = 115/250 (46%), Gaps = 18/250 (7%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSD--LKKEAEEKHARALRIRSELETERVQKLQRTSQ 273
R+ + ++ ++L E+ +K + L KE+EE+ R R R E E + + + Q
Sbjct: 1301 REEEQLLQEREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHEKEHLLREREEQQ 1360
Query: 274 KLNRVSEWHAVRHLKLREGMYARHQRSE-SRHEAFLAQ---VAKRAGDESSKVNEV--RF 327
+ E + +LR QR + R FL + + + +E +V E +F
Sbjct: 1361 LRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEEQSLQREREEEKRRVQEQDRKF 1420
Query: 328 ITS---LNEENKKLILRQKLHGSELRRAEKL--QVIKSKQKEDLAREEAVLERRKLIEAE 382
+ L+ E ++ + R++ + R E+ + + +Q+++L +EE +RR+
Sbjct: 1421 LEQEEQLHREEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEE---QRRRQERER 1477
Query: 383 KLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKE-ERAKAQQEEAELLAQKL 441
K + +++R+++E Q +R +ER + R+ ++ RR+ E K Q A + + L
Sbjct: 1478 KFREEEQLRRQQQEEQ-KRRQERDVQQSRRQVWEEDKGRRQVLEAGKRQFASAPVRSSPL 1536
Query: 442 AERLNESEQR 451
E + E +
Sbjct: 1537 YEYIQEQRSQ 1546
>PLE1_HUMAN (Q15149) Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1)
(HD1)
Length = 4684
Score = 69.3 bits (168), Expect = 6e-11
Identities = 109/472 (23%), Positives = 204/472 (43%), Gaps = 50/472 (10%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMN--AWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAE 220
L+ + ++ K+KE + L + A++ +R E + R++ E
Sbjct: 1985 LKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELE 2044
Query: 221 RVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSE 280
R + L + + ++++ L +A + A A + ELE R++ + + +E
Sbjct: 2045 RQKGLVEDTLR-QRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 2103
Query: 281 WHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENK---- 336
A R +L R + +E R + LA + A + + EV + + EE +
Sbjct: 2104 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRE 2163
Query: 337 --------KLILRQKLHGSELRRAEKLQVIKSKQKED-----LAREEAVLERRKLIEAEK 383
+L L Q+ L+ EK +QKE L +E++VL+R + EAE
Sbjct: 2164 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRG-EAEA 2222
Query: 384 LQRLAE------MQRKKEEAQIRR---EEERKASSAAREARA-------IEQLRRKEERA 427
+R AE +Q ++E AQ RR E ER SA +A+A E+LR++ E+
Sbjct: 2223 ARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE 2282
Query: 428 KAQQEEAELLAQKLAERLNESEQRRKIYLEQ-IRERANLRDQSSPLLRRSLNKDGQGRST 486
A++ +AE A + + + ++ K + EQ +R++A + +Q LR L + ++
Sbjct: 2283 AARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV-EQELTTLRLQLEETDHQKNL 2341
Query: 487 PNNSSD--DSQTNIASGLGSSL--GIGSITLQ----HSMKRRIKRIRQKLMALKYEFLEP 538
+ ++ A+ S + + S+ +Q +K RI+ + L+ + +
Sbjct: 2342 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2401
Query: 539 PLGGESAGIGYRVAVGAARAKVGRWLQELQRLRQARKEGATSIGLIISEMIK 590
L E+ + +VA AAR V QE RLRQ +E + +M+K
Sbjct: 2402 FLQEEAEKM-KQVAEEAARLSVA--AQEAARLRQLAEEDLAQQRALAEKMLK 2450
Score = 69.3 bits (168), Expect = 6e-11
Identities = 114/514 (22%), Positives = 211/514 (40%), Gaps = 62/514 (12%)
Query: 10 ILSSSLEAFRKIQQERASLKLSNNTEHAMSKCLTSESVGNMNGTHNAKNS-RTKSRKHIG 68
++ +L R++++E +LK S + A K +G + NA+++ R+K + +
Sbjct: 2049 LVEDTLRQRRQVEEEILALKASFE-KAAAGKAELELELGRIRS--NAEDTLRSKEQAELE 2105
Query: 69 SSDANQGNLNVKKHNIEGTKPC--------DAIRVQKGYIPPESLLTSEVDLAKLPSLEN 120
++ Q ++ E + +A R +K + L ++V+ A+ SL
Sbjct: 2106 AARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEAR--SLRE 2163
Query: 121 SSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNL----------------- 163
+ +A+ A K L ++KA + +K L
Sbjct: 2164 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAA 2223
Query: 164 RRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVR 223
RR + E+ + + +S +E + + ++ + RK AE+
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2283
Query: 224 TLHDKLMSPEKKKKTTSDLKKEAEEKHA-----RALRIRSELETERVQKLQRTSQKLNRV 278
+ ++K +D + E +K A + ++ EL T R+Q L+ T + N +
Sbjct: 2284 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ-LEETDHQKNLL 2342
Query: 279 SEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKL 338
E ++ LK E A QRS+ E F +V +E SK+ + EN+ L
Sbjct: 2343 DE--ELQRLKA-EATEAARQRSQVEEELFSVRVQM---EELSKLK-----ARIEAENRAL 2391
Query: 339 ILRQKLHGSEL--RRAEKL-QVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKE 395
ILR K + AEK+ QV + + +A +EA R+ E QR + KE
Sbjct: 2392 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2451
Query: 396 EAQIRREEERKASSAAREARAIEQLRR-KEERAKAQQEEAELLAQKLAE------RLNES 448
+ Q +E R + EA ++Q + +E+A+ QE+ E +AQ+LAE R E+
Sbjct: 2452 KMQAVQEATRLKA----EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2507
Query: 449 EQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQ 482
E++R++ + ER LR + +D Q
Sbjct: 2508 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2541
Score = 64.3 bits (155), Expect = 2e-09
Identities = 111/522 (21%), Positives = 210/522 (39%), Gaps = 52/522 (9%)
Query: 105 LLTSEVDLAKLP--SLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDN 162
L +EV+ A+ +LE + A A++++ S A+K L+ E + R
Sbjct: 1689 LCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1748
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNW--------EDILSSPFRVSSRMSYSPSL 214
R Q Q + E+ + + W+ K N E++L +
Sbjct: 1749 RRAQQQA---EAERAREEAERQLERWQLKANEALRLRLQAEEVLQQKSLAQAEAEKQKEE 1805
Query: 215 GRKSAER--------VRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQ 266
+ A R VR EK+++ ++ +R+R+E E Q
Sbjct: 1806 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1865
Query: 267 KLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVR 326
+ Q ++L R+ A K R+ + A + + E LA AK +E S+
Sbjct: 1866 R-QLLEEELARLQREAAAATQK-RQELEAELAKVRAEMEVLLASKAK--AEEESR----- 1916
Query: 327 FITSLNEENKKLILRQKLHGSEL-RRAEKLQVIKSKQK-------EDLAREEAVLERRKL 378
S +E++K+ + + EL A +L+ + + K ED AR+ A ER
Sbjct: 1917 ---STSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER--- 1970
Query: 379 IEAEKLQRLAEMQRKKEEAQIRREEERKASSAAR---EARAIEQLRRKEERAKAQQEEAE 435
+ AEKL + E R K EA+I +E+ + R E A ++ R +E+ A+ + + E
Sbjct: 1971 VLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEE 2030
Query: 436 LLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQ 495
LAQ +E E+++ + + +R+R + ++ L+ S K G++ +
Sbjct: 2031 RLAQLRKASDSELERQKGLVEDTLRQRRQVEEEIL-ALKASFEKAAAGKAELELELGRIR 2089
Query: 496 TNIASGLGSSLGIGSITLQHSMKRRIKRIRQKLMALKYEFLEPPLGGESAGIGYRVAVGA 555
+N L S L+ + +R++ ++ E ++ L E R A
Sbjct: 2090 SNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE 2146
Query: 556 ARAKVGRWLQELQRLRQ-ARKEGATSIGLIISEMIKYLEGKD 596
++ ++E + LR+ A +E A + L K L+ ++
Sbjct: 2147 EVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEE 2188
Score = 63.2 bits (152), Expect = 4e-09
Identities = 103/476 (21%), Positives = 203/476 (42%), Gaps = 46/476 (9%)
Query: 16 EAFRKIQQERASLKLSNNTEHAMSKCLTSESVGNMNGTHNAKNSRTKSRKHIGSSDANQG 75
EA R+ Q E+A+L+ + M K + + + T R + +D +
Sbjct: 2282 EAARRAQAEQAALRQKQAADAEMEKH-KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2340
Query: 76 NLNVKKHNIEGTKPCDAIRVQKGYIPPESLLTSEVDLAKLPSL------ENSSALATAKV 129
L+ + ++ + +A R Q+ + E L + V + +L L EN + + K
Sbjct: 2341 LLDEELQRLKA-EATEAAR-QRSQVE-EELFSVRVQMEELSKLKARIEAENRALILRDKD 2397
Query: 130 KTH--LGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNA 187
T L A+K+ + ++A + + R QL E+D ++ K +
Sbjct: 2398 NTQRFLQEEAEKMKQVAEEAARLSV------AAQEAARLRQLAEEDLAQQRALAEKML-- 2449
Query: 188 WKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAE 247
KEK + + + L ++ A R++ DK ++ + T ++ E
Sbjct: 2450 -KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ--EDKEQMAQQLAEETQGFQRTLE 2506
Query: 248 EKHARALRIRSELETE--RVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSE--SR 303
+ R L + +E E RV ++ R + +E A R K E + + R+E ++
Sbjct: 2507 AERQRQLEMSAEAERLKLRVAEMSRAQAR----AEEDAQRFRKQAEEIGEKLHRTELATQ 2562
Query: 304 HEAFLAQVAK----RAGDESSKVNEVRFITSLNEENKKLILRQKL------HGSELRRAE 353
+ L Q + ++ ++ ++ E I L E +KL KL +++ +
Sbjct: 2563 EKVTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ 2620
Query: 354 KLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAARE 413
LQ ++ Q+ L+ ++++L+R + IE EK + Q + +AQ REE+++ +
Sbjct: 2621 LLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2680
Query: 414 ARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQI-RERANLRDQ 468
R ++L E A+ +Q EAE ++ E L + EQ+R+ E + E LR+Q
Sbjct: 2681 ER--QRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2734
Score = 57.0 bits (136), Expect = 3e-07
Identities = 73/360 (20%), Positives = 150/360 (41%), Gaps = 33/360 (9%)
Query: 146 KAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKS--MNAWKEKRNWEDILSSPFR 203
KA E R+ RQ+QL ++ +KR + K+ ++++ + L
Sbjct: 2152 KAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2211
Query: 204 VSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETE 263
V R+ R++AE + ++ + +++ EE A L+ +E + +
Sbjct: 2212 VLDRLRGEAEAARRAAEEAEEAR------VQAEREAAQSRRQVEE--AERLKQSAEEQAQ 2263
Query: 264 RVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSES---RHEAFLAQVAKRAGDESS 320
+ Q ++KL + +E A R + + + Q +++ +H+ F Q ++
Sbjct: 2264 ARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQ 2323
Query: 321 KVNEVRFITSLNEENKKLILR--QKLHGSELRRAEKLQVIKSK------QKEDLAREEAV 372
++ +R + K L+ Q+L A + ++ + Q E+L++ +A
Sbjct: 2324 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKAR 2383
Query: 373 LE--RRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQ 430
+E R LI +K +Q + E+ + EE + S AA+EA + QL E AQ
Sbjct: 2384 IEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA---EEDLAQ 2440
Query: 431 QE--EAELLAQKL-----AERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQG 483
Q ++L +K+ A RL + + E +E+A + + + L ++ QG
Sbjct: 2441 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2500
Score = 54.7 bits (130), Expect = 2e-06
Identities = 59/273 (21%), Positives = 117/273 (42%), Gaps = 17/273 (6%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLK-KEAEEKHARALRIRSELETERVQKLQRTSQKLNRV 278
++ R++ ++L + + K ++AE LRI E+ R+Q Q+
Sbjct: 1550 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE 1609
Query: 279 SEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKL 338
E A+R A Q+ +++ EA ++ ++ DES + + + + +
Sbjct: 1610 GELQALR----ARAEEAEAQKRQAQEEA--ERLRRQVQDESQRKRQAEVELASRVKAEAE 1663
Query: 339 ILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQ 398
R+K L+ E+L++ + + L + E R+ + E QR AE + + + A
Sbjct: 1664 AAREKQRA--LQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRAS 1721
Query: 399 IRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ-------R 451
+ + S E A+ QLR + ER QQ EAE A++ AER E Q R
Sbjct: 1722 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERQLERWQLKANEALR 1780
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
++ E++ ++ +L + + ++ + R
Sbjct: 1781 LRLQAEEVLQQKSLAQAEAEKQKEEAEREARRR 1813
Score = 53.5 bits (127), Expect = 3e-06
Identities = 77/321 (23%), Positives = 151/321 (46%), Gaps = 40/321 (12%)
Query: 164 RRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVR 223
R +L ++ +E+ +++A ++KR+ ++ L + S + + ++AER R
Sbjct: 1525 REAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR 1584
Query: 224 TLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
++ + + + ++ ++ E +ALR R+E + ++ Q +++L R
Sbjct: 1585 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR-----Q 1639
Query: 284 VRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQK 343
V+ R+ S + EA A+ +RA + E+R L E + L Q
Sbjct: 1640 VQDESQRKRQAEVELASRVKAEAEAAREKQRA---LQALEELR----LQAEEAERWLCQ- 1691
Query: 344 LHGSELRRAEKLQV-IKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEE-----A 397
+E+ RA ++QV +++ Q+ EA L+ ++ AEK A+++R +E A
Sbjct: 1692 ---AEVERARQVQVALETAQRS----AEAELQSKRASFAEK---TAQLERSLQEEHVAVA 1741
Query: 398 QIRREEERKASSAAREARAIEQLRRKEERAKAQQEEA--------ELLAQK-LAERLNES 448
Q+R E ER+A A RA E+ R+ ER + + EA E+L QK LA+ E+
Sbjct: 1742 QLREEAERRAQQQAEAERAREEAERQLERWQLKANEALRLRLQAEEVLQQKSLAQA--EA 1799
Query: 449 EQRRKIYLEQIRERANLRDQS 469
E++++ + R R +Q+
Sbjct: 1800 EKQKEEAEREARRRGKAEEQA 1820
Score = 52.4 bits (124), Expect = 7e-06
Identities = 71/314 (22%), Positives = 145/314 (45%), Gaps = 51/314 (16%)
Query: 146 KAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWK-----EKRNWEDILSS 200
KA E++ ++ + + RR ++DKE+ + L + ++ E++ ++ +
Sbjct: 2463 KAEAELLQQQKELAQEQARRL----QEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2518
Query: 201 PFRVSSR---MSYSPSLGRKSAERVRT--------LHDKLMSPEKKKKTTSDLKKEAEEK 249
R+ R MS + + + A+R R LH ++ ++K L+ + ++
Sbjct: 2519 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2578
Query: 250 HARALRIR---SELETERVQKLQRTSQKLNRVSE-WHAVRHLKLREGMYARHQRSESRHE 305
A R+R +ELE E+ +KLQ+ ++ L SE V+ +L Q +++ +
Sbjct: 2579 DHDAERLREAIAELEREK-EKLQQEAKLLQLKSEEMQTVQQEQLL-------QETQALQQ 2630
Query: 306 AFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKED 365
+FL++ + S + RFI +E KL ++L E+ +A++L+ + +Q++
Sbjct: 2631 SFLSE-------KDSLLQRERFI---EQEKAKL---EQLFQDEVAKAQQLREEQQRQQQQ 2677
Query: 366 LAREEAVL------ERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQ 419
+ +E L RR+ EAE+ R + + ++ E Q R++EE A R ++
Sbjct: 2678 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2737
Query: 420 LRRKEERAKAQQEE 433
L + A A EE
Sbjct: 2738 LEEQHRAALAHSEE 2751
Score = 47.4 bits (111), Expect = 2e-04
Identities = 81/358 (22%), Positives = 155/358 (42%), Gaps = 52/358 (14%)
Query: 161 DNLRRQMQLPEKDKEKRSTSLGKSMNAWKEK-----RNWEDILSSPFRVSSRMSYSPSLG 215
D LR ++ E+ ++R + W+E+ W+ +L+ + R LG
Sbjct: 1288 DELRGAQEVGER-LQQRHGERDVEVERWRERVAQLLERWQAVLA---QTDVRQRELEQLG 1343
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALR----IRSELETER--VQKLQ 269
R+ L S + D ++ E+ A L +R +L E+ +++++
Sbjct: 1344 RQ-------LRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIE 1396
Query: 270 RTSQKLNRVSEW-----HAVRHLKLREGMYARHQRSESRHEAFLAQVAK-RAGDESSKVN 323
R +K+ + +A++ +L+ Y +++ A A+ K ++G ES
Sbjct: 1397 RHGEKVEECQRFAKQYINAIKDYELQLVTY----KAQLEPVASPAKKPKVQSGSESVIQE 1452
Query: 324 EVRFITSLNEENKKLILRQKLHGSELRRAEKLQVI----KSKQKEDLAREEAVLERRKLI 379
V T +E K LRR E+ + + +++++E LA EA LE+++ +
Sbjct: 1453 YVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL 1512
Query: 380 EAEKLQRLAEMQRKKEEAQIRREE-----ERKASSAAREARAI----EQLRRKEE---RA 427
Q A+ +R+ +E Q R +E E A A ++ R+I +QLR+ E +A
Sbjct: 1513 AEAHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA 1572
Query: 428 KAQQEEAELLAQKLAERLNESEQRRKIYLEQI-RERANLRDQSSPLLRRSLNKDGQGR 484
KA+Q EA A++ R+ E + ++ LE R+R + L R+ + Q R
Sbjct: 1573 KARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKR 1627
Score = 38.1 bits (87), Expect = 0.15
Identities = 77/404 (19%), Positives = 157/404 (38%), Gaps = 35/404 (8%)
Query: 109 EVDLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQ 168
E+ L KL + + SA+ K+KT L+ + EV+ + +
Sbjct: 1205 ELTLGKLEQVRSLSAIYLEKLKTI------SLVIRGTQGAEEVLRAHEEQLKEAQAVPAT 1258
Query: 169 LPEKDKEKRSTSLGKSMNAWKEKRN-----WEDILSSPFRVSSRMSYSPSLGRKSAERVR 223
LPE + K S K + A E + D L V R+ ER R
Sbjct: 1259 LPELEATKASL---KKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWR 1315
Query: 224 TLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
+L+ + +D+++ E+ R LR E LQ ++ ++
Sbjct: 1316 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1375
Query: 284 VRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEV--RFITSLNEENKKLILR 341
+RE + R E L + +R G++ + ++I ++ + +L+
Sbjct: 1376 ADSQAVREQL---------RQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTY 1426
Query: 342 QKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERR----KLIEAEKLQRLAEMQRKKEEA 397
+ A+K +V E + +E L + ++ ++ ++E R+ EE
Sbjct: 1427 KAQLEPVASPAKKPKV--QSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1484
Query: 398 QIRREEERKASSAAREARAIEQLRRKEERAKAQQE---EAELLAQKLAERLNESEQRRKI 454
+ R E+++A R A L ++ + A+A + +AE A++L +R+ E RR+
Sbjct: 1485 E-RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVRREE 1543
Query: 455 YLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNI 498
+++ + LR+S + Q ++ +++ S+ I
Sbjct: 1544 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1587
>MYH9_HUMAN (P35579) Myosin heavy chain, nonmuscle type A (Cellular
myosin heavy chain, type A) (Nonmuscle myosin heavy
chain-A) (NMMHC-A)
Length = 1960
Score = 68.9 bits (167), Expect = 8e-11
Identities = 83/360 (23%), Positives = 154/360 (42%), Gaps = 26/360 (7%)
Query: 128 KVKTHLGSGADKLLSLKDKAPTEVIN-EKNPRSTDNL--------------RRQMQLPEK 172
K KT L D LL D N EK + D L R + + +
Sbjct: 1413 KTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAR 1472
Query: 173 DKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSR--MSYSPSLGRKSAERVRTLHDKLM 230
+KE ++ SL +++ E++ + L+ FR MS +G+ E ++
Sbjct: 1473 EKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 231 SPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLR 290
E+ K +L+ E + LR+ L+ + Q +R Q + SE + ++
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQ-FERDLQGRDEQSEEKKKQLVRQV 1591
Query: 291 EGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELR 350
M A + + R + +A A++ + K E ++ ++ + +KL
Sbjct: 1592 REMEA--ELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 351 RAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQ---RLAEMQRKKEEAQIRREE--ER 405
+L ++ ++E LA+ + ++ K +EAE +Q LA +R K +AQ R+E +
Sbjct: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
Query: 406 KASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANL 465
A+S+ + A A+E+ RR E R +EE E Q E +N+ ++ + ++QI NL
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELE-EEQGNTELINDRLKKANLQIDQINTDLNL 1768
Score = 57.0 bits (136), Expect = 3e-07
Identities = 67/265 (25%), Positives = 122/265 (45%), Gaps = 30/265 (11%)
Query: 220 ERVRTLHDKLMSPEKKKKTTSDLKK-------EAEEKHARALRIRSELETERVQKLQRTS 272
+R+ L E+K K+ + LK + EE+ R + R ELE R +KL+ S
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR-RKLEGDS 1057
Query: 273 QKLN-RVSEWHA-VRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITS 330
L+ +++E A + LK++ + E +A LA+V + A ++ + ++R + S
Sbjct: 1058 TDLSDQIAELQAQIAELKMQLA------KKEEELQAALARVEEEAAQKNMALKKIRELES 1111
Query: 331 LNEE-----NKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEK-- 383
E + R K + E+L+ +K++ ++ L A E R E E
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI 1171
Query: 384 LQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKE---ERAK--AQQEEAELL- 437
L++ E + K EAQI+ ++ + + A +EQ +R + E+AK + E EL
Sbjct: 1172 LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 1231
Query: 438 -AQKLAERLNESEQRRKIYLEQIRE 461
+ L + +SE +RK Q++E
Sbjct: 1232 EVKVLLQGKGDSEHKRKKVEAQLQE 1256
Score = 50.4 bits (119), Expect = 3e-05
Identities = 75/330 (22%), Positives = 147/330 (43%), Gaps = 52/330 (15%)
Query: 220 ERVRTLHDKLMSPEKK-----KKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQK 274
E+ + D+L++ EK + + EA EK +AL + LE QK + ++
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL--ER 1497
Query: 275 LNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
LN+ ++ + M ++ +S HE + +KRA ++ +V E++ T L E
Sbjct: 1498 LNKQFR------TEMEDLMSSKDDVGKSVHEL---EKSKRALEQ--QVEEMK--TQLEEL 1544
Query: 335 NKKLILRQKLHGSELRRAEKLQVIKSKQKEDL-AREEAVLERRKLI-----------EAE 382
+L Q ++LR LQ +K++ + DL R+E E++K + E E
Sbjct: 1545 EDEL---QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDE 1601
Query: 383 KLQR-LAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
+ QR +A RKK E ++ E S+ AI+QLR+ + + K E
Sbjct: 1602 RKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE-------- 1653
Query: 442 AERLNESEQRRKIYLEQIRE-RANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIAS 500
L+++ R+ L Q +E L+ + +++ L ++ + + +A
Sbjct: 1654 ---LDDTRASREEILAQAKENEKKLKSMEAEMIQ--LQEELAAAERAKRQAQQERDELAD 1708
Query: 501 GLGSSLGIGSITLQHS--MKRRIKRIRQKL 528
+ +S G G++ L+ ++ RI ++ ++L
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEEL 1738
Score = 43.1 bits (100), Expect = 0.005
Identities = 75/366 (20%), Positives = 154/366 (41%), Gaps = 54/366 (14%)
Query: 144 KDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWE-DILSSPF 202
K K+ ++ N+ TD L +++ EK +++ K +R E D
Sbjct: 1014 KSKSLAKLKNKHEAMITD-LEERLRREEKQRQELE----------KTRRKLEGDSTDLSD 1062
Query: 203 RVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELET 262
+++ + L + A++ L L E++ + K+ E ++ ++ +LE+
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLES 1122
Query: 263 ERVQKLQRTSQKLNRVSEWHAVR-HLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSK 321
ER + + QK + E A++ L+ A Q S+ E + + K+ +E +K
Sbjct: 1123 ERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV-NILKKTLEEEAK 1181
Query: 322 VNEVRFITSLNEENKKLI--LRQKLHGSELRRA--EKLQVIKSKQKEDLAREEAVL---- 373
+E + I + +++ + + L ++L ++ +A EK + ++ +LA E VL
Sbjct: 1182 THEAQ-IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 374 ----ERRKLIEAEKLQRLAEMQRKKEEAQIRREE----------------------ERKA 407
+RK +EA+ L E+Q K E + R E + K+
Sbjct: 1241 GDSEHKRKKVEAQ----LQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKS 1296
Query: 408 SSAAREARAIE-QLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLR 466
S ++ A+E QL+ +E + + + L+ KL + +E R+ E+ + NL
Sbjct: 1297 SKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE 1356
Query: 467 DQSSPL 472
Q + L
Sbjct: 1357 KQIATL 1362
Score = 41.6 bits (96), Expect = 0.013
Identities = 66/311 (21%), Positives = 126/311 (40%), Gaps = 30/311 (9%)
Query: 251 ARALRIRSELETERVQKLQRTSQKLNRVSEWHAVR-HLKLREGMYARHQRSESR-HEAFL 308
AR + + + ++ LQR ++ W R K++ + Q E E L
Sbjct: 795 ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
Query: 309 AQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSEL-RRAEKLQVIKSKQKEDLA 367
+V ++ +++ E+ + S K + Q +EL AE+L+ + +K++L
Sbjct: 855 VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
Query: 368 REEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERA 427
LE R E E+ Q L ++K ++ EE+ + +AR+ +E++ + +
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 428 KAQQE-------------EAELLAQKLAE---RLNESEQRRK----------IYLEQIRE 461
K ++E E +LL ++AE L E E++ K + + E
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 462 RANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIGSITLQHSMKRRI 521
R ++ L ++ K + ++ + Q IA L L LQ ++ R
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE-LKMQLAKKEEELQAALARVE 1093
Query: 522 KRIRQKLMALK 532
+ QK MALK
Sbjct: 1094 EEAAQKNMALK 1104
Score = 41.2 bits (95), Expect = 0.017
Identities = 89/437 (20%), Positives = 165/437 (37%), Gaps = 57/437 (13%)
Query: 103 ESLLTSEVDLAK-LPSLENSSALATAKV---KTHLGSGADKLLSLKD------------K 146
E L++S+ D+ K + LE S +V KT L D+L + +D K
Sbjct: 1507 EDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 147 APTEVINEKNPRSTDNLRRQM--QLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRV 204
A E + ++ ++Q+ Q+ E + E +SM K+ D+ +
Sbjct: 1567 AQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626
Query: 205 SSR-------MSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIR 257
S + L + + +R L D S E+ + +K+ + A ++++
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 258 SELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGD 317
EL K Q ++ E + G A + R EA +AQ+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADE------IANSSGKGALALEEKRRLEARIAQLEEELEE 1740
Query: 318 ESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRK 377
E + N+ KK L+ ++L QK + AR++ LER+
Sbjct: 1741 EQGNTELI------NDRLKKANLQIDQINTDLNLERS-----HAQKNENARQQ--LERQN 1787
Query: 378 LIEAEKLQRLAEMQRKKE-------EAQIRREEERKASSAAREARAIEQLRRKEERAK-- 428
KLQ + + K EA+I + EE+ + A +Q+RR E++ K
Sbjct: 1788 KELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 429 -AQQEEAELLAQKLAERLNESEQR---RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
Q ++ A++ ++ +++ R K LE+ E A + S L+R L +
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 485 STPNNSSDDSQTNIASG 501
N + + G
Sbjct: 1908 DAMNREVSSLKNKLRRG 1924
>IF3A_MAIZE (Q9XHR2) Eukaryotic translation initiation factor 3
subunit 10 (eIF-3 theta) (Eukaryotic translation
initiation factor 3 large subunit) (eIF3a)
Length = 962
Score = 67.4 bits (163), Expect = 2e-10
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 42/311 (13%)
Query: 214 LGRKSA--ERVRTLHDKLMSPEKK--KKTTSDLKKEAEEKHARAL---------RIRSEL 260
L RKS +R L +++ EK+ KK S KK +E+ R L RIR E+
Sbjct: 563 LARKSIIEKRKEELERQILEKEKEEEKKRMSSQKKTVDEERVRLLNEQRQREQDRIRREI 622
Query: 261 ETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMY---ARHQRSESRHE---------AFL 308
E + + ++ + LN+ + H V +L + Y AR+++ + RHE +
Sbjct: 623 EEKNKAEAKKMLEDLNKAGKKHVVVEGELTKEAYMELARNEQLKERHEMEKKLQKFAKTM 682
Query: 309 AQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAR 368
+ + E + + E F L EE IL ++ E+ +++ ++K L+R
Sbjct: 683 DYLERAKRQEEAPLIEQAFQKRLEEEK---ILHEQEQLREIELSKQHHASDLQEKNRLSR 739
Query: 369 EEAVLERRKLIEAEKLQ-RLAEMQRKKEEAQIRREEERKASSAAREARAIEQ----LRRK 423
+LE + ++ +Q R AE R K+E R R SS E + + L +
Sbjct: 740 ---MLEHKNALQERIIQERAAEFGRLKKERDERM--NRLISSRKHERETVRKLMFYLNLE 794
Query: 424 EERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLR----DQSSPLLRRSLNK 479
E+R + +EE E ++ ER E RK L+ I E+ LR ++ + R L K
Sbjct: 795 EQRIEMLREEEEARKREAEERRKREEAERKAKLDAIAEKQRLREIELEEKAKATREKLLK 854
Query: 480 DGQGRSTPNNS 490
+ P+++
Sbjct: 855 GSEAVRAPDSA 865
Score = 49.3 bits (116), Expect = 6e-05
Identities = 84/376 (22%), Positives = 149/376 (39%), Gaps = 43/376 (11%)
Query: 145 DKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRV 204
D+ ++NE+ R D +RR+++ EK+K + L A K+ V
Sbjct: 600 DEERVRLLNEQRQREQDRIRREIE--EKNKAEAKKMLEDLNKAGKKH----------VVV 647
Query: 205 SSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALR--IRSELET 262
++ + E+++ H+ +K KT L++ ++ A + + LE
Sbjct: 648 EGELTKEAYMELARNEQLKERHEMEKKLQKFAKTMDYLERAKRQEEAPLIEQAFQKRLEE 707
Query: 263 ERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKV 322
E++ Q +++ +S+ H L+ + + + + E + + A G +
Sbjct: 708 EKILHEQEQLREI-ELSKQHHASDLQEKNRLSRMLEHKNALQERIIQERAAEFGRLKKER 766
Query: 323 NE--VRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE 380
+E R I+S E + + E +R E L ++E+ AR+ ERRK E
Sbjct: 767 DERMNRLISSRKHERETVRKLMFYLNLEEQRIEML------REEEEARKREAEERRKREE 820
Query: 381 AE---KLQRLAEMQRKK-----EEAQIRREEERKASSAAR--EARAIEQLRRKEERAKAQ 430
AE KL +AE QR + E+A+ RE+ K S A R ++ + Q R+ A A
Sbjct: 821 AERKAKLDAIAEKQRLREIELEEKAKATREKLLKGSEAVRAPDSAPVAQPPRESAAAAAA 880
Query: 431 QEEAELLAQKLAERLNESEQRRKIYL-----EQIRERANLRDQSSP--LLRRSLNKD--- 480
A K + I ++ R LR P L S +D
Sbjct: 881 AAAAAPAPSKYIPKFKRGGDSSSIPSGSRDEDRWGSRGPLRQDGPPARLDAPSSRQDTDR 940
Query: 481 GQGRSTPNNSSDDSQT 496
+G P+NS+ S T
Sbjct: 941 WRGSRFPSNSTSSSST 956
>AZI1_MOUSE (Q62036) 5-azacytidine induced protein 1 (Pre-acrosome
localization protein 1)
Length = 1060
Score = 67.0 bits (162), Expect = 3e-10
Identities = 78/386 (20%), Positives = 174/386 (44%), Gaps = 40/386 (10%)
Query: 159 STDNLRRQMQLPEKDKE----KRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSL 214
ST +R +++L EK + +R+ + + + + K E L+ R + Y ++
Sbjct: 547 STSVMRLKLELEEKKQAMALLQRALAQQRDLTVRRVKET-EKELTRQLR-QQKEQYEATI 604
Query: 215 GRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRS--ELETERVQKLQRTS 272
R + + + DK + EK + ++LK + R +++ ELE +++++L +
Sbjct: 605 QRHLSFIDQLIEDKKVLSEKCEAVVAELKHGDQRCRERVAQMQEQHELEIKKLKELMSAT 664
Query: 273 QKLNRVSEWHAVRHLKLRE----GMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI 328
+K+ R +W + K++E G+ Q+ ++H+ EVR +
Sbjct: 665 EKIRR-EKWINEKTKKIKEITVRGLEPEIQKLIAKHK-----------------QEVRRL 706
Query: 329 TSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE-AEKLQRL 387
L+E + Q LR+AE+L+ +++E L ++E +++ + E+ QR
Sbjct: 707 RGLHEAELQQREEQAAQ-RHLRQAEELRQHLDREREVLGQQERERAQQRFEQHLEQEQRA 765
Query: 388 AEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNE 447
E QR++ ++ E+ER AAR+ +E+LR++ E + A A L + E
Sbjct: 766 LEQQRRRLYNEVAEEKERLGQQAARQRAELEELRQQLEESSAALTRA--LRAEFERSREE 823
Query: 448 SEQRRKIYLEQIRERANLRDQS--SPLLRRS----LNKDGQGRSTPNNSSDDSQTNIASG 501
E+R ++ L+ ++++ Q+ + ++ L ++ + + D +
Sbjct: 824 QERRHQMELKALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHR 883
Query: 502 LGSSLGIGSITLQHSMKRRIKRIRQK 527
L + + + + + + R+KR+R K
Sbjct: 884 LEADMTLAKEESERAAESRVKRVRDK 909
Score = 51.2 bits (121), Expect = 2e-05
Identities = 72/287 (25%), Positives = 131/287 (45%), Gaps = 51/287 (17%)
Query: 214 LGRKSAERVRTLHDKLMSPEKK------KKTTSDLKKEAEEKHARALRIRSELETERVQK 267
LG++ ER + ++ + E++ ++ +++ +E E +A R R+ELE R Q+
Sbjct: 743 LGQQERERAQQRFEQHLEQEQRALEQQRRRLYNEVAEEKERLGQQAARQRAELEELR-QQ 801
Query: 268 LQRTSQKLNRVSEWHAVRHLKLREGMYARHQRS--------ESRHEAFLAQVAKRAGDES 319
L+ +S L R R RE RHQ E+ +A++A AK+ +E+
Sbjct: 802 LEESSAALTRALRAEFERS---REEQERRHQMELKALKDQLEAERQAWVASCAKK--EEA 856
Query: 320 SKVNEVRFITSLNEENKK-------LILRQ-----KLHGSELRRAEKLQVIKSKQKEDLA 367
+ R L EE +K L++ + L E RA + +V + + K +
Sbjct: 857 WLLTRER---ELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAESRVKRVRDKYETE 913
Query: 368 REEAVLERRKLIE--AEKLQRLAEMQRKKEEAQ-IRREEERKA-------SSAAREARAI 417
E RKL E +E RL E + +KE Q + R++E++ + E ++
Sbjct: 914 LSELEQSERKLQERCSELKGRLGEAEGEKERLQSLVRQKEKELEDLRAVNTQMCSERASL 973
Query: 418 EQLRRKE--ERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRER 462
Q+ R+E E+ A QEE Q++ L E + R+++ L+++ R
Sbjct: 974 AQVVRQEFAEQLAASQEE----TQRVKVELAELQARQQVELDEVHRR 1016
Score = 43.9 bits (102), Expect = 0.003
Identities = 65/331 (19%), Positives = 135/331 (40%), Gaps = 45/331 (13%)
Query: 125 ATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPE--KDKEKRSTSLG 182
A + + HL L + + EV EK R++ +L E + E+ S +L
Sbjct: 751 AQQRFEQHLEQEQRALEQQRRRLYNEVAEEKERLGQQAARQRAELEELRQQLEESSAALT 810
Query: 183 KSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDL 242
+++ A E+ E R+ ++ L D+L + E++ S
Sbjct: 811 RALRAEFERSREEQ------------------ERRHQMELKALKDQLEA-ERQAWVASCA 851
Query: 243 KKEAEEKHARALRIRSELETERVQKLQRTSQKLN-----------RVSEWHAVRHLKLRE 291
KKE R ++ E+ R Q+++ +L R +E R E
Sbjct: 852 KKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAESRVKRVRDKYE 911
Query: 292 GMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSEL-- 349
+ ++SE + + +++ R G+ + ++ SL + +K + + +++
Sbjct: 912 TELSELEQSERKLQERCSELKGRLGEAEGEKERLQ---SLVRQKEKELEDLRAVNTQMCS 968
Query: 350 RRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASS 409
RA QV++ + E LA + +R K+ LAE+Q +++ ++ R ++
Sbjct: 969 ERASLAQVVRQEFAEQLAASQEETQRVKV-------ELAELQA-RQQVELDEVHRRVKTA 1020
Query: 410 AAREARAIEQLRRKEERAKAQQEEAELLAQK 440
AR+ A+ LR++ E A + + E L ++
Sbjct: 1021 LARKEAAVNSLRKQHEAAVKRADHLEELLEQ 1051
>SPEN_DROME (Q8SX83) Split ends protein
Length = 5560
Score = 66.6 bits (161), Expect = 4e-10
Identities = 88/386 (22%), Positives = 160/386 (40%), Gaps = 31/386 (8%)
Query: 169 LPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYS-PSLGRKSAERVRTLHD 227
LPE K+ R T N K + SSP RV + S S P A +L
Sbjct: 1733 LPEMGKQSRLTGQSSGNNLTKSLSVPDGPQSSPARVQLQKSASVPGSTNVGAPSSLSLDS 1792
Query: 228 KLMSPEKKKKTTSDLKKEAEEKHARALRIRSE-----LETERVQKL-----QRTSQKLNR 277
S E +S + A+ ++ +E E +K Q +S +
Sbjct: 1793 TTASVETSASISSSTSNGNSSLTSAAIHVQKPQQSTFVEEEHTKKSGTSTSQSSSSSSKK 1852
Query: 278 VSEWHAVRHLKLREGMYARHQ---------RSESRHEAFLAQVAK----RAGDESSKVNE 324
+S H H K + + S+ R + +Q +K R D+SS+ ++
Sbjct: 1853 ISSTHDKLHSKHNNRSESDKKIKKSDKNASSSDKRKNSSTSQSSKSATPRIEDDSSEADD 1912
Query: 325 VRFITSLNEENKKLIL-RQKLHGSELRR-AEKLQVIKSKQKEDLAREEA-VLERRKLIEA 381
N+ ++K RQ+ +LR+ E+ + + Q+E+ +E+ E K E
Sbjct: 1913 TADKAEKNQRHEKEKKERQEKREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEEKERER 1972
Query: 382 EKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKL 441
EK + ++++EE ++R +E+R +E R + LR KE+R + +E+ EL + L
Sbjct: 1973 EKKAQEDREKKEREERELREKEQRDKEQKEKEIRE-KDLREKEQRERDNREK-ELRDKDL 2030
Query: 442 AER-LNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIAS 500
E+ + E EQR K L + +++ + RR+++ + +GR Q +
Sbjct: 2031 REKEMREKEQREK-ELHREKDQREREHREKEQSRRAMDVEQEGRGGRMRELSSYQKSKMD 2089
Query: 501 GLGSSLGIGSITLQHSMKRRIKRIRQ 526
G + + +I QH+ + + I Q
Sbjct: 2090 IAGEASSLTAIDCQHNKENAMDTIAQ 2115
Score = 40.8 bits (94), Expect = 0.023
Identities = 74/327 (22%), Positives = 119/327 (35%), Gaps = 71/327 (21%)
Query: 51 NGTHNAKNSRTKSRKHIGSSDANQGNLNVKKHNIEGTKPCDAIRVQKGYIPPESLLTSEV 110
+GT +++S + S+K + D N + + + K D S
Sbjct: 1838 SGTSTSQSSSSSSKKISSTHDKLHSKHNNRSESDKKIKKSDKN-------------ASSS 1884
Query: 111 DLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLP 170
D K S SS AT +++ D DKA EKN R + + +
Sbjct: 1885 DKRKNSSTSQSSKSATPRIEDDSSEADDTA----DKA------EKNQRHEKEKKERQEKR 1934
Query: 171 EKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLM 230
EKD K+ K A +E+R ED RK+ E +
Sbjct: 1935 EKDLRKQVEREEKDRKAQQEEREKED-------------------RKAKEEEK------- 1968
Query: 231 SPEKKKKTTSDL-KKEAEEKHAR--ALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHL 287
E++KK D KKE EE+ R R + + E E +K R ++ R + +R
Sbjct: 1969 EREREKKAQEDREKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDK 2028
Query: 288 KLRE-GMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHG 346
LRE M + QR + H R D+ + + + + + + + Q+ G
Sbjct: 2029 DLREKEMREKEQREKELH---------REKDQREREHREK-----EQSRRAMDVEQEGRG 2074
Query: 347 SELRRAEKLQVIKSKQKEDLAREEAVL 373
+R Q K K D+A E + L
Sbjct: 2075 GRMRELSSYQ----KSKMDIAGEASSL 2097
>CALD_CHICK (P12957) Caldesmon (CDM)
Length = 771
Score = 66.2 bits (160), Expect = 5e-10
Identities = 102/471 (21%), Positives = 185/471 (38%), Gaps = 52/471 (11%)
Query: 147 APTEVINEKNPRSTDNL------------RRQMQLPE-----KDKEKRSTSLGKSMNAWK 189
A V E+ RSTD+ RRQ +L E K+ + T S+ + +
Sbjct: 70 AQNSVAEEETKRSTDDEAALLERLARREERRQKRLQEALERQKEFDPTITDGSLSVPSRR 129
Query: 190 EKRNWED--ILSSPFRVSSRMSY----SPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLK 243
E N E+ I +V +R KS +R D +K++K + + K
Sbjct: 130 EVNNVEENEITGKEEKVETRQGRCEIEETETVTKSYQRNNWRQDGEEEGKKEEKDSEEEK 189
Query: 244 KEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRH----------LKLREGM 293
+ + + E T++ + ++ + +N ++ +A+ + E
Sbjct: 190 PKEVPTEENQVDVAVEKSTDKEEVVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAE 249
Query: 294 YARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAE 353
R + E A+ K+A +E K E + EE ++ ++ +E R
Sbjct: 250 KEREKLEAEEKERLKAEEEKKAAEEKQKAEEEK---KAAEERERAKAEEEKRAAEERERA 306
Query: 354 KLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAARE 413
K + + K E+ R +A ER+ E K AE +RK E + + EEERKA+ +
Sbjct: 307 KAEE-ERKAAEERERAKAEEERKAAEERAK----AEEERKAAEERAKAEEERKAAEERAK 361
Query: 414 ARAIEQLRRKEERAKAQQEE--AELLAQKLAERLNESEQRRKIYLEQIRERAN-LRDQSS 470
A + + ERAKA++E+ AE A+ AE+L E ++ + ++ + +AN LR Q
Sbjct: 362 AEKERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQANLLRKQEE 421
Query: 471 PLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIGSITLQHSMKRRIKRIRQKLMA 530
+ + + S P S+ + ++ R+ QK
Sbjct: 422 D---KEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMKSVWDRKRGVPEQKAQN 478
Query: 531 LKYEFLEPPLGGESAGIGYRVAVGAARAKVGRWLQELQRLRQARKEGATSI 581
+ E P L G GAA A+ G ++L++ ++E A +
Sbjct: 479 GERELTTPKLKSTENAFGRSNLKGAANAEAGS-----EKLKEKQQEAAVEL 524
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/411 (20%), Positives = 171/411 (40%), Gaps = 60/411 (14%)
Query: 114 KLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKD 173
++P+ EN +A K K L++ + T + E TD ++ + EK+
Sbjct: 192 EVPTEENQVDVAVEKSTDKEEVVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAEKE 251
Query: 174 KEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPE 233
+EK + + A +EK+ E+ + + + ER + +K + E
Sbjct: 252 REKLEAEEKERLKAEEEKKAAEE---------KQKAEEEKKAAEERERAKAEEEKRAAEE 302
Query: 234 KKKKTTSDLKKEAEEKHA-------RALRIRSELETERVQKLQRTSQKLNRVSEWHAVRH 286
+++ + +K AEE+ +A R++ E ER +R + R + A
Sbjct: 303 RERAKAEEERKAAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKA---AEER 359
Query: 287 LKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKL---ILRQK 343
K + A +R ++ E ++A E+ K+ E + + + +K +LR++
Sbjct: 360 AKAEKERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQANLLRKQ 419
Query: 344 LHGSELR--------------RAEKLQVIKSKQKEDLAREE--AVLERRKLIEAEKLQR- 386
E + ++K QV +K KE +EE +V +R++ + +K Q
Sbjct: 420 EEDKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMKSVWDRKRGVPEQKAQNG 479
Query: 387 ---LAEMQRKKEEAQIRREEERKASSAAREARAIEQL------------RRKEERAKAQQ 431
L + K E R + A++A + +++ +R+EER K +
Sbjct: 480 ERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQQEAAVELDELKKRREERRKILE 539
Query: 432 EEAELLAQKLAER-LNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDG 481
EE + Q+ AER + E E+++++ E R RA ++ R+ + +DG
Sbjct: 540 EEEQKKKQEEAERKIREEEEKKRMKEEIERRRAEAAEK-----RQKVPEDG 585
Score = 59.3 bits (142), Expect = 6e-08
Identities = 76/312 (24%), Positives = 136/312 (43%), Gaps = 31/312 (9%)
Query: 154 EKNPRSTDNLRRQMQLPEKDK--------EKRSTSLGKSMNAWKEKRNWEDILSSPFRVS 205
E+ R RQ +L +K++ EK + S+ + KR+ +D + R++
Sbjct: 35 EEAARERRRRARQERLRQKEEGDVSGEVTEKSEVNAQNSVAEEETKRSTDDEAALLERLA 94
Query: 206 SRMSYSPSLGRKSAERVR----TLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELE 261
R +++ ER + T+ D +S +++ + + E K + + E
Sbjct: 95 RREERRQKRLQEALERQKEFDPTITDGSLSVPSRREVNNVEENEITGKEEKVETRQGRCE 154
Query: 262 TERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSK 321
E + + ++ Q+ N + K E + E E VA + +
Sbjct: 155 IEETETVTKSYQRNNWRQDGE--EEGKKEEKDSEEEKPKEVPTEENQVDVAVEKSTDKEE 212
Query: 322 VNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEA 381
V E + + ++N EN + L G + + + KE +EEA ER KL EA
Sbjct: 213 VVETKTL-AVNAENDTNAM---LEGEQ-------SITDAADKE---KEEAEKEREKL-EA 257
Query: 382 EKLQRL-AEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQK 440
E+ +RL AE ++K E + + EEE+KA+ A+A E+ R EER +A+ EE A++
Sbjct: 258 EEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAAEERERAKAEEERKAAEE 317
Query: 441 LAERLNESEQRR 452
ER E+R+
Sbjct: 318 -RERAKAEEERK 328
Score = 45.1 bits (105), Expect = 0.001
Identities = 62/304 (20%), Positives = 127/304 (41%), Gaps = 18/304 (5%)
Query: 154 EKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPS 213
E+ ++ + + + + +KE+++ + A +EKR E+ + ++
Sbjct: 344 EERAKAEEERKAAEERAKAEKERKAAEERERAKAEEEKRAAEEKARLE---AEKLKEKKK 400
Query: 214 LGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQ 273
+ K A+ + + L E+ K+ + KKE+ + L+ S+ + + K + +
Sbjct: 401 MEEKKAQEEKAQANLLRKQEEDKEAKVEAKKESLPEK---LQPTSKKDQVKDNKDKEKAP 457
Query: 274 KLNRVSEWHAVRHLKLREGMYARHQ----RSESRHEAFLAQVAK-----RAGDESSKVNE 324
K S W R + ++ + + +S AF K AG E K +
Sbjct: 458 KEEMKSVWDRKRGVPEQKAQNGERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQ 517
Query: 325 VRFITSLNEENKKLILRQK-LHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEK 383
L+E K+ R+K L E ++ ++ K +++E+ R + +ERR+ AEK
Sbjct: 518 QEAAVELDELKKRREERRKILEEEEQKKKQEEAERKIREEEEKKRMKEEIERRRAEAAEK 577
Query: 384 LQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAE 443
Q++ E EE + + K SS E RA E L + +++ + + K+
Sbjct: 578 RQKVPE-DGVSEEKKPFKCFSPKGSSLKIEERA-EFLNKSAQKSGMKPAHTTAVVSKIDS 635
Query: 444 RLNE 447
RL +
Sbjct: 636 RLEQ 639
Score = 43.9 bits (102), Expect = 0.003
Identities = 42/129 (32%), Positives = 62/129 (47%), Gaps = 23/129 (17%)
Query: 334 ENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRK 393
E ++ + RQK L AE+L S Q+ D EEA ERR+ E+L R+
Sbjct: 5 ERRRELRRQKREEMRLE-AERL----SYQRNDDDEEEAARERRRRARQERL-------RQ 52
Query: 394 KEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRK 453
KEE + E K+ A+ + A +EE ++ +EA LL ERL E+RR+
Sbjct: 53 KEEGDVSGEVTEKSEVNAQNSVA------EEETKRSTDDEAALL-----ERLARREERRQ 101
Query: 454 IYLEQIRER 462
L++ ER
Sbjct: 102 KRLQEALER 110
Score = 33.9 bits (76), Expect = 2.8
Identities = 52/265 (19%), Positives = 106/265 (39%), Gaps = 17/265 (6%)
Query: 7 RADILSSSLEAFRKIQQERASLKLSNNTEHAMSKCLTSESVGNMNGTHNAKNSRTKSRKH 66
+A + + L+ +K+++++A E A + L + K S + +
Sbjct: 387 KARLEAEKLKEKKKMEEKKAQ------EEKAQANLLRKQEEDKEAKVEAKKESLPEKLQP 440
Query: 67 IGSSDANQGNLNVKKHNIEGTKPCDAIRVQKGYIPPESLLTSEVDLA--KLPSLENSSAL 124
D + N + +K E K ++ +K +P + E +L KL S EN+
Sbjct: 441 TSKKDQVKDNKDKEKAPKEEMK---SVWDRKRGVPEQKAQNGERELTTPKLKSTENAFGR 497
Query: 125 ATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKS 184
+ K + +G++KL + +A E+ K R RR++ E+ K+K+ + K
Sbjct: 498 SNLKGAANAEAGSEKLKEKQQEAAVELDELKKRREE---RRKILEEEEQKKKQEEAERKI 554
Query: 185 MNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKK 244
++KR E+I + + P G ++ S K ++ L K
Sbjct: 555 REEEEKKRMKEEIERRRAEAAEKRQKVPEDGVSEEKKPFKCFSPKGSSLKIEERAEFLNK 614
Query: 245 EAEE---KHARALRIRSELETERVQ 266
A++ K A + S++++ Q
Sbjct: 615 SAQKSGMKPAHTTAVVSKIDSRLEQ 639
>MST2_DROHY (Q08696) Axoneme-associated protein mst101(2)
Length = 1391
Score = 65.9 bits (159), Expect = 7e-10
Identities = 71/334 (21%), Positives = 145/334 (43%), Gaps = 14/334 (4%)
Query: 163 LRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERV 222
L ++ + EK+K K+ GK A KEK+ ++ + + +++AE+
Sbjct: 738 LAKKKKAGEKNKLKKGNKKGKK--ALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKK 795
Query: 223 R---TLHDKLMSPEKKK-KTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRV 278
+ T + EKKK + T+ +KEA EK + E +K ++T++K
Sbjct: 796 KCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKCEKTAKKRKET 855
Query: 279 SEWHAVRHLKLREGMYARHQRSES----RHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
+E + A ++ E R EA + A + ++ E + ++
Sbjct: 856 AEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEAAKK 915
Query: 335 NKKLILRQK---LHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQ 391
K++ R+K L + AEK + K +KE A E+ L+++ +K ++L +
Sbjct: 916 EKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGKKS 975
Query: 392 RKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQR 451
++ E + E +K AA + + E+ ++++E A+ +Q E K A + E+R
Sbjct: 976 KRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEER 1035
Query: 452 RKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRS 485
K L++ E+ +++ L + K + R+
Sbjct: 1036 AK-KLKEAAEKKQCEERAKKLKEAAEQKQCEERA 1068
Score = 65.9 bits (159), Expect = 7e-10
Identities = 88/434 (20%), Positives = 173/434 (39%), Gaps = 49/434 (11%)
Query: 171 EKDKE----KRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLH 226
+K+KE K+ L K + EK+ + + + + G K ++ + L
Sbjct: 914 KKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAG-KGKKKCKKLG 972
Query: 227 DKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQ--RTSQKLNRVSEWHAV 284
K +KKK KKE E + R++ + E +K Q ++KL +E
Sbjct: 973 KKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQC 1032
Query: 285 --RHLKLREGMY--------------ARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI 328
R KL+E A ++ E R + K+ +E +K +
Sbjct: 1033 EERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEAAE 1092
Query: 329 TSLNEENKKLILR--QKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQR 386
EE K + +K E + EK K + +E RE+ E++K EA K ++
Sbjct: 1093 KKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKKEK 1152
Query: 387 LA-EMQRKKEEAQIRRE--EERKASSAAREARAIEQLRRKEERAKAQQEEAELL-AQKLA 442
A E Q+ E A+ +E E++K + AA+ + Q ++ + AK +QE AE+ ++ A
Sbjct: 1153 EATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPAEMKKCEEAA 1212
Query: 443 ERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGL 502
++ E+ +++K +E+ + + + + + + + +
Sbjct: 1213 KKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEAAKKEKEAE----- 1267
Query: 503 GSSLGIGSITLQHSMKRRIKRIRQKLMALKYEFLEPPLGGESAGIGYRVAVGAARAKVGR 562
K+R +K ALK + + + + A + + A+ A +AK+
Sbjct: 1268 ---------------KKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAA 1312
Query: 563 WLQELQRLRQARKE 576
+E ++L + KE
Sbjct: 1313 EKKECEKLAKKAKE 1326
Score = 65.9 bits (159), Expect = 7e-10
Identities = 65/342 (19%), Positives = 152/342 (44%), Gaps = 30/342 (8%)
Query: 168 QLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHD 227
++ E+ ++K+ +L K EK+ +++ + K E
Sbjct: 341 KMKEEAEKKKCAALAKKQKEEDEKKACKELAKKKKEADEK---------KKCEEAANKEK 391
Query: 228 KLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHL 287
K +K +K + K+ AE+K + + ER +K + ++ + + +E +
Sbjct: 392 KAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEAAER-KKCEELAKNIKKAAEKKKCKEA 450
Query: 288 KLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGS 347
+E A ++ E LA+ K+A ++ + + E K L +K+ +
Sbjct: 451 AKKEKEAAERKKCEE-----LAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKA 505
Query: 348 ELRRAEKLQVIKSKQKEDLAR---EEAVLERRKLIE-------AEKLQRLAEMQRKKEEA 397
E+++ K + + K+KE + E+A +R++ E A+K + AE ++ ++ A
Sbjct: 506 EIKK--KCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSA 563
Query: 398 QIRRE--EERKASSAAREARAIEQLRRKEERAKAQQEEAE-LLAQKLAERLNESEQRRKI 454
+ R+E E++K AA+E + + ++ EE AK ++E AE ++LA+++ ++ +++K
Sbjct: 564 KKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKC 623
Query: 455 YLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQT 496
+E+ + L + + K + + + + +T
Sbjct: 624 KEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKET 665
Score = 63.2 bits (152), Expect = 4e-09
Identities = 78/346 (22%), Positives = 160/346 (45%), Gaps = 29/346 (8%)
Query: 144 KDKAPTEVINEKNPRSTDNLRRQMQLPEKDKE----KRSTSLGKSMNAWKEKRNWEDILS 199
K K + + +K+ R+ + ++ + +K+KE K+ K EK+ E+
Sbjct: 963 KGKKKCKKLGKKSKRAAEK-KKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAK 1021
Query: 200 SPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHA--RALRIR 257
+ + + A++++ +K E+ KK LK+ AE+K RA +++
Sbjct: 1022 KLKEAAEQKQCE-----ERAKKLKEAAEKKQCEERAKK----LKEAAEQKQCEERAKKLK 1072
Query: 258 SELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARH--QRSESRHEAFLAQVAKRA 315
E ++ ++ + ++ + R KL+E + +R++ EA + + A
Sbjct: 1073 EAAEKKQCEERAKKEKEAAEKKQCEE-RAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEA 1131
Query: 316 GDESSKVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLER 375
+ E + ++ K+ +QK +E + EK K K E RE+ ++
Sbjct: 1132 AKREKEAAEKKKCAEAAKKEKEATEKQKC--AEAAKKEKEAAEKKKCAEAAKREKEAAQK 1189
Query: 376 RKLIE-AEKLQRLAEMQRKKEEAQIRRE---EERKASSAAREARAIEQLRRKEERAKAQQ 431
+K + A+K Q AEM +K EEA + + E++K + AA++ + + ++ E AK +Q
Sbjct: 1190 KKCADLAKKEQEPAEM-KKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQ 1248
Query: 432 EEAE-LLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRS 476
E AE + A++ E+E++RK E+ + A L+ Q + L+ R+
Sbjct: 1249 EAAEKKKCAEAAKKEKEAEKKRK--CEKAEKAAALKRQCAKLVIRA 1292
Score = 60.1 bits (144), Expect = 4e-08
Identities = 65/244 (26%), Positives = 123/244 (49%), Gaps = 19/244 (7%)
Query: 217 KSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQK-LQRTSQKL 275
KS+E + K +K+K+ ++ KE E+ A+ + E++ + +K L++ + L
Sbjct: 279 KSSEPKKKGKKKKNDEKKEKELEREILKEQAEEEAKIRGVVKEVKKKCKEKALKKKCKDL 338
Query: 276 NRVSEWHAVRHLKLREGMYARHQRSESRHEAF--LAQVAKRAGDESSKVNEVRFITSLNE 333
R + A K + A+ Q+ E +A LA+ K A DE K E + N+
Sbjct: 339 GRKMKEEAE---KKKCAALAKKQKEEDEKKACKELAKKKKEA-DEKKKCEE-----AANK 389
Query: 334 ENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE-AEKLQRLAEMQR 392
E KK ++K + R E + K K +E +E+ ER+K E A+ +++ AE ++
Sbjct: 390 E-KKAAEKKKCEKAAKERKEAAE--KKKCEEAAKKEKEAAERKKCEELAKNIKKAAEKKK 446
Query: 393 KKEEAQIRRE--EERKASSAAREARAIEQLRRKEERAKAQQEEAE-LLAQKLAERLNESE 449
KE A+ +E E +K A++ + + ++ EE AK +E AE ++LA+++ ++E
Sbjct: 447 CKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAE 506
Query: 450 QRRK 453
++K
Sbjct: 507 IKKK 510
Score = 59.3 bits (142), Expect = 6e-08
Identities = 73/317 (23%), Positives = 131/317 (41%), Gaps = 43/317 (13%)
Query: 155 KNPRSTDNLRRQMQLPEKDKE----KRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSY 210
KN + ++ + +K+KE K+ L K + EK+ E+ V+ R
Sbjct: 436 KNIKKAAEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAKKGKEVAER--- 492
Query: 211 SPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAE--EKHARALRIRSELETERVQKL 268
++ L K+ E KKK KKE E EK + E +K
Sbjct: 493 ---------KKCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKC 543
Query: 269 QRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI 328
++ ++K +E + ++ R EA + ++A E + E +
Sbjct: 544 EKAAKKRKEAAEKKKCE------------KSAKKRKEAAEKKKCEKAAKERKEAAEKKKC 591
Query: 329 TSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE-AEKLQRL 387
++ K++ R+K EL + K K K KE +E+ ER K E A+K+++
Sbjct: 592 EEAAKKEKEVAERKKCE--ELAKKIKKAAEKKKCKEAAKKEKEAAEREKCGELAKKIKKA 649
Query: 388 AEMQRKKEEAQIRRE--EERKASSAAREARAIEQLRR--------KEERAKAQQEEAELL 437
AE ++ K+ A+ +E E++K AA++ + + ++ KE K + EEA
Sbjct: 650 AEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKK 709
Query: 438 AQKLAERLNESEQRRKI 454
++ AER E +KI
Sbjct: 710 EKEAAERKKCEELAKKI 726
Score = 54.3 bits (129), Expect = 2e-06
Identities = 71/337 (21%), Positives = 134/337 (39%), Gaps = 35/337 (10%)
Query: 119 ENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLR---RQMQLPEKDKE 175
E + L A + A KL +K E +K + + + R +L E ++
Sbjct: 1050 ERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKQCEERAKKLKEAAEK 1109
Query: 176 KRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKK 235
K+ K EK+ E+ + + + + + E+ T K KK
Sbjct: 1110 KQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKK---EKEATEKQKCAEAAKK 1166
Query: 236 KKTTSDLKK---------EAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWH---- 282
+K ++ KK EA +K A + E E ++K + ++K +E
Sbjct: 1167 EKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPAEMKKCEEAAKKEKEAAEKQKCAK 1226
Query: 283 -------AVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEEN 335
A K E + +E + A A+ K A ++ K + +L +
Sbjct: 1227 AAKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEAAKKEKEA-EKKRKCEKAEKAAALKRQC 1285
Query: 336 KKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKE 395
KL++R K E +K +I K K ++E +K EA + ++ A++ +KK
Sbjct: 1286 AKLVIRAK----EAALRKKCAIIAKKAKMAAEKKECEKLAKKAKEAIEWKKCAKLAKKKR 1341
Query: 396 EAQIRREEERKASSAAREARAIEQLRRKEERAKAQQE 432
EA E+++ A A +E A E+ +R ++ AK +++
Sbjct: 1342 EA----EKKKCAKLAKKEKEAAEKKKRCKDLAKNKKK 1374
Score = 53.5 bits (127), Expect = 3e-06
Identities = 85/414 (20%), Positives = 163/414 (38%), Gaps = 44/414 (10%)
Query: 57 KNSRTKSRKHIGSSDANQGNLN-VKKHNIEGTKPCDAI-----RVQKGYIPPESLLTSEV 110
K + K K + + G N +KK +G K C + R + E+ +
Sbjct: 934 KAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKE 993
Query: 111 DLAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKNPRSTDNLR---RQM 167
K E + A K A KL ++ E +K + + + R
Sbjct: 994 AATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAK 1053
Query: 168 QLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHD 227
+L E ++K+ K + EK+ E+ + + + A++++ +
Sbjct: 1054 KLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKQCE-----ERAKKLKEAAE 1108
Query: 228 KLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHL 287
K E+ KK +KEA EK + E E +K ++K E A
Sbjct: 1109 KKQCEERAKK-----EKEAAEKKRCEEAAKREKEAAEKKKCAEAAKK-----EKEATEKQ 1158
Query: 288 KLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGS 347
K E A + E+ + A+ AKR + + K + + +E ++ ++
Sbjct: 1159 KCAE---AAKKEKEAAEKKKCAEAAKREKEAAQK-KKCADLAKKEQEPAEMKKCEEAAKK 1214
Query: 348 ELRRAEKLQVIKS--KQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEER 405
E AEK + K+ K+KE +++ +K EA + ++ AE +K++EA+ +R+ E+
Sbjct: 1215 EKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEAAKKEKEAEKKRKCEK 1274
Query: 406 KASSAAREARAIEQLRRKEERA--------------KAQQEEAELLAQKLAERL 445
+AA + + + + R +E A A+++E E LA+K E +
Sbjct: 1275 AEKAAALKRQCAKLVIRAKEAALRKKCAIIAKKAKMAAEKKECEKLAKKAKEAI 1328
Score = 48.9 bits (115), Expect = 8e-05
Identities = 57/243 (23%), Positives = 108/243 (43%), Gaps = 18/243 (7%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKL 275
+K E ++ +K ++ +KK AE+K + + + ER +K ++K+
Sbjct: 588 KKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAER-EKCGELAKKI 646
Query: 276 NRVSEWHAVRHLKLREGMYARHQRSES----RHEAFLAQVAKRAGDESSKVNEVRFITSL 331
+ +E + L +E A ++ E R EA + A + + E +
Sbjct: 647 KKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEA 706
Query: 332 NEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQ 391
++ K+ R+K EL + K K K K+ LA+++ E+ KL + K + A +
Sbjct: 707 AKKEKEAAERKKCE--ELAKKIKKAAEKKKCKK-LAKKKKAGEKNKLKKGNKKGKKALKE 763
Query: 392 RKK--EEAQIRREEERKASSAAR-EARAIEQLR-------RKEERAKAQQEEAELLAQKL 441
+KK E A+ + E++K AA+ E A E+ + RKEE K + E+ ++
Sbjct: 764 KKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEA 823
Query: 442 AER 444
AE+
Sbjct: 824 AEK 826
Score = 48.5 bits (114), Expect = 1e-04
Identities = 72/332 (21%), Positives = 137/332 (40%), Gaps = 52/332 (15%)
Query: 155 KNPRSTDNLRRQMQLPEKDKE----KRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSY 210
K + + ++ +L +K+KE K+ K EK+ E + +
Sbjct: 500 KKIKKAEIKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKC 559
Query: 211 SPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQR 270
KSA++ + +K KK + + +KEA EK + E E +K +
Sbjct: 560 E-----KSAKKRKEAAEK-----KKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEE 609
Query: 271 TSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITS 330
++K+ + +E K +E + +E LA+ K+A E K ++
Sbjct: 610 LAKKIKKAAE-----KKKCKEAAKKEKEAAEREKCGELAKKIKKAA-EKKKCKKLAKKEK 663
Query: 331 LNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLA-----------REEAVLERRKLI 379
E KK +K AEK + ++ +KE A +E+ ER+K
Sbjct: 664 ETAEKKKC---EKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCE 720
Query: 380 E-AEKLQRLAEMQRKKEEAQIRREEE--------RKASSAAREARAIEQLRRK------- 423
E A+K+++ AE ++ K+ A+ ++ E +K A +E + +L +K
Sbjct: 721 ELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKK 780
Query: 424 -EERAKAQQEEAE-LLAQKLAERLNESEQRRK 453
+E AK ++E AE +K A++ E +++K
Sbjct: 781 CKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKK 812
>YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome III
precursor
Length = 887
Score = 65.5 bits (158), Expect = 9e-10
Identities = 75/315 (23%), Positives = 138/315 (43%), Gaps = 26/315 (8%)
Query: 145 DKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRV 204
+K E + ++ L R+ +L E+ + R L + + E+ E + R
Sbjct: 318 EKMEQERLRQEKEEKARELERRRKL-EESETARQAELDRQATIYAEQ---ERMAMERNRE 373
Query: 205 SSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETER 264
R+ L K E R +++ K + L+ E + K+ R +R ELE R
Sbjct: 374 LERIR----LEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNER---VRQELEAAR 426
Query: 265 VQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNE 324
KLQ ++ R + V ++R+ AR ++ E ++ + +E + ++
Sbjct: 427 KYKLQEEERQ--RKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEELERQHQ 484
Query: 325 VRFITSLNEENKKLILRQKLHGSELRRAEKLQ--VIKSKQKEDLAREEAVLERRKLIEAE 382
+ + E+ KK L + E + AE+L +I+ + KE+ + +RK++E E
Sbjct: 485 MEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKE 544
Query: 383 KLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQ--LRRKEERAK--AQQEEAELLA 438
R + +EE + EEER+ E R I+Q + EER++ A + E E+L
Sbjct: 545 MEDRQNAIY--EEEERRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREMLR 602
Query: 439 QKLAERLNESEQRRK 453
Q + ESE++RK
Sbjct: 603 Q-----IKESEKQRK 612
Score = 58.9 bits (141), Expect = 8e-08
Identities = 58/232 (25%), Positives = 104/232 (44%), Gaps = 23/232 (9%)
Query: 261 ETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESS 320
E E + +L Q VSE + E R ++ E E L + K E++
Sbjct: 291 ENEFLNQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARE--LERRRKLEESETA 348
Query: 321 KVNEVRFITSLNEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIE 380
+ E+ ++ E +++ + + +R EK ++ E + +EE +E K+ E
Sbjct: 349 RQAELDRQATIYAEQERMAMERNRELERIRLEEK-----KRENERVRQEEIAMEISKIRE 403
Query: 381 AEKLQRLAEMQRKKEEAQ--------IRREEERKASSAAREARAIEQLRRKEERAKAQQE 432
E+LQ E QRK E + + +EE + ++ +EQ+R++EE A+QE
Sbjct: 404 LERLQ--LERQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEE---ARQE 458
Query: 433 EAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGR 484
+ +L + ER E E+ R+ LE+ + LR Q ++ L KD + R
Sbjct: 459 QLRVLEE---ERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQR 507
Score = 58.5 bits (140), Expect = 1e-07
Identities = 61/246 (24%), Positives = 116/246 (46%), Gaps = 36/246 (14%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKL 275
R + ER R L + + E+KK+ +++E +R L+ ER +K +R Q+L
Sbjct: 365 RMAMERNREL--ERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVRQEL 422
Query: 276 NRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEEN 335
A R KL+E QR + + + Q+ ++ E ++ ++R L EE
Sbjct: 423 E------AARKYKLQE---EERQRKIQQQKVEMEQIRQQ---EEARQEQLRV---LEEER 467
Query: 336 KKLILRQKLHGSELRRAEKLQVIKSKQKEDLARE-EAVLERRKLIEAEKLQRLAEMQRKK 394
+ + +++ EL R ++++++ ++++ ++ E E+R+ EAE+L R+ + K
Sbjct: 468 AREL--ERVRQEELERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMK 525
Query: 395 EEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKI 454
E Q EE+ K +E E+R A EE E R+ E E+R++I
Sbjct: 526 ENKQKMIEEKNKRKMLEKEM---------EDRQNAIYEEEE-------RRIAEEERRKQI 569
Query: 455 YLEQIR 460
+E+ R
Sbjct: 570 EIEERR 575
Score = 57.0 bits (136), Expect = 3e-07
Identities = 58/255 (22%), Positives = 116/255 (44%), Gaps = 28/255 (10%)
Query: 227 DKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRH 286
++L+ + +KT S+ +++ + + R+R E E E+ ++L+R
Sbjct: 296 NQLLHIVQHQKTVSERQQQEKFEKMEQERLRQEKE-EKARELERRR-------------- 340
Query: 287 LKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHG 346
KL E AR Q R A+ + A + + ++ +R E + +
Sbjct: 341 -KLEESETAR-QAELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEI 398
Query: 347 SELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEE-R 405
S++R E+LQ+ + ++ E + +E + KL E E+ +++ Q+K E QIR++EE R
Sbjct: 399 SKIRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKI--QQQKVEMEQIRQQEEAR 456
Query: 406 KASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANL 465
+ E +L R + +Q + E+L Q + E ++K LE+ RE+
Sbjct: 457 QEQLRVLEEERARELERVRQEELERQHQMEILRQ-------QEEDQKKKKLEKDREQRE- 508
Query: 466 RDQSSPLLRRSLNKD 480
+ ++ L R + K+
Sbjct: 509 QQEAEELNRMIIEKE 523
>IF3A_TOBAC (Q40554) Eukaryotic translation initiation factor 3
subunit 10 (eIF-3 theta) (Eukaryotic translation
initiation factor 3 large subunit) (eIF3a) (PNLA-35)
Length = 958
Score = 64.3 bits (155), Expect = 2e-09
Identities = 90/362 (24%), Positives = 151/362 (40%), Gaps = 59/362 (16%)
Query: 159 STDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKS 218
S D +RR + D K +SL + K+ L+ + M Y P+ +K+
Sbjct: 486 SVDAVRRNFLAIKVDHMKGLSSLVNRVLRRKDSGIICLFLAESLSKARTMIYPPA--KKA 543
Query: 219 AERVRTLHDKLMSPEKKKKTT----SDLKKEAEEKHARALRIRSELETER--VQKLQRTS 272
A+ L + EK+ K S ++K EE+ L + ET+R VQK+ +
Sbjct: 544 AKLGEALSNLAEIVEKEHKRLLARKSIIEKRKEEQERLLLEMERVEETKRRDVQKMTEEA 603
Query: 273 QKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFIT--- 329
++ +E+ R+ ++ + + R +A L + KR+ + V E +T
Sbjct: 604 EQKRIAAEYEQRRNQRILKEI---EDRELEEAQALLHEAEKRSKRKKKPVLEGEKMTKKV 660
Query: 330 ----SLNEE-------NKKLILRQKL--HGSELRRAEKLQVIKSKQKEDLAREEAVLERR 376
+LNE+ KKL+ K H +R E +I+S K+ LA E A+ ER
Sbjct: 661 IMELALNEQLRERQEMEKKLLKFAKSMDHLERAKREEAAPLIESAFKQRLAEEAALHERE 720
Query: 377 KLIEAE-----------KLQRLAEM-------------QRKKEEAQIRREEERKASSAAR 412
+ E E + +RLA M R+ E +++RE + + S +
Sbjct: 721 QQQEIELSRQRHAGDLEEKRRLARMLENKRILQEKVVSSREAEFTRMKRERQERISQIIQ 780
Query: 413 EARAIEQLRRK--------EERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERAN 464
+ + RRK EER K QEE E ++ AER + E R+ L++I E+
Sbjct: 781 SRKQEREARRKMIFFLRSEEERQKRLQEEEEARKREEAERRKKEEAERQAKLDEIAEKQR 840
Query: 465 LR 466
R
Sbjct: 841 RR 842
Score = 58.5 bits (140), Expect = 1e-07
Identities = 69/310 (22%), Positives = 135/310 (43%), Gaps = 47/310 (15%)
Query: 216 RKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARA-------LRIRSELETERVQKL 268
++ E+ R L + E K++ + +EAE+K A RI E+E +++
Sbjct: 573 KRKEEQERLLLEMERVEETKRRDVQKMTEEAEQKRIAAEYEQRRNQRILKEIEDRELEEA 632
Query: 269 Q--------RTSQKLNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAG---- 316
Q R+ +K V E + + E R E L + AK
Sbjct: 633 QALLHEAEKRSKRKKKPVLEGEKMTKKVIMELALNEQLRERQEMEKKLLKFAKSMDHLER 692
Query: 317 ---DESSKVNEVRFITSLNEE--------NKKLILRQKLHGSELRRAEKL-QVIKSK--- 361
+E++ + E F L EE +++ L ++ H +L +L +++++K
Sbjct: 693 AKREEAAPLIESAFKQRLAEEAALHEREQQQEIELSRQRHAGDLEEKRRLARMLENKRIL 752
Query: 362 QKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEEAQ------IRREEER-KASSAAREA 414
Q++ ++ EA R K E++ ++ + ++++ EA+ +R EEER K EA
Sbjct: 753 QEKVVSSREAEFTRMKRERQERISQIIQSRKQEREARRKMIFFLRSEEERQKRLQEEEEA 812
Query: 415 RAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLR 474
R E+ R+++ +Q + + +A+K R+ E E++ K RER + +S+ +L
Sbjct: 813 RKREEAERRKKEEAERQAKLDEIAEKQRRRMLELEEKEK------REREEILRKSTAVLP 866
Query: 475 RSLNKDGQGR 484
+ GR
Sbjct: 867 KPAEPPTLGR 876
Score = 55.1 bits (131), Expect = 1e-06
Identities = 72/346 (20%), Positives = 144/346 (40%), Gaps = 22/346 (6%)
Query: 112 LAKLPSLENSSALATAKVKTHLGSGADKLLSLKDKAPTEVINEKN---PRSTDNLRRQMQ 168
LA+ S + AK LG L + +K ++ K+ R + R ++
Sbjct: 525 LAESLSKARTMIYPPAKKAAKLGEALSNLAEIVEKEHKRLLARKSIIEKRKEEQERLLLE 584
Query: 169 LPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAERVRTLHDK 228
+ ++ KR + + E+ + I + + ++ R+ E LH+
Sbjct: 585 MERVEETKR-----RDVQKMTEEAEQKRIAAEYEQRRNQRILKEIEDRELEEAQALLHEA 639
Query: 229 LMSPEKKKKTTSDLKKEAEEKHARA-----LRIRSELETERVQKLQRTSQKLNRVSEWHA 283
++KKK + +K ++ LR R E+E +++ K ++ L R A
Sbjct: 640 EKRSKRKKKPVLEGEKMTKKVIMELALNEQLRERQEME-KKLLKFAKSMDHLERAKREEA 698
Query: 284 VRHL----KLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLI 339
+ K R A E + E L++ + AGD K R + + +K++
Sbjct: 699 APLIESAFKQRLAEEAALHEREQQQEIELSR-QRHAGDLEEKRRLARMLENKRILQEKVV 757
Query: 340 LRQKLHGSELRRAEK---LQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKKEE 396
++ + ++R + Q+I+S+++E AR + + R E +K + E RK+EE
Sbjct: 758 SSREAEFTRMKRERQERISQIIQSRKQEREARRKMIFFLRSEEERQKRLQEEEEARKREE 817
Query: 397 AQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLA 442
A+ R++EE + + E ++ R E K ++E E+L + A
Sbjct: 818 AERRKKEEAERQAKLDEIAEKQRRRMLELEEKEKREREEILRKSTA 863
>MYH9_RAT (Q62812) Myosin heavy chain, nonmuscle type A (Cellular
myosin heavy chain, type A) (Nonmuscle myosin heavy
chain-A) (NMMHC-A)
Length = 1961
Score = 63.9 bits (154), Expect = 2e-09
Identities = 101/431 (23%), Positives = 186/431 (42%), Gaps = 58/431 (13%)
Query: 77 LNVKKHNIEG-TKPCDAIRVQKGYIPPESLLTSEVDLAKLPSLENSSALATAKVKTHLGS 135
LN +H E K + +V++ ++ E+ LT + E + KT L +
Sbjct: 838 LNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAKTELCA 897
Query: 136 GADKL---LSLKDKAPTEVINEKNPRSTDNLRR------------------QMQLPEKDK 174
A++L L+ K + E+ ++ R + R + QL E++
Sbjct: 898 EAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEES 957
Query: 175 EKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKSAE-RVRTLHDKLMSPE 233
++ L K K K+ ED + + + + +K E RV LM E
Sbjct: 958 ARQKLQLEKVTTEAKLKKLEEDQI-----IMEDQNCKLAKEKKLLEDRVAEFTTDLMEEE 1012
Query: 234 KKKKTTSDLKK-------EAEEKHARALRIRSELETERVQKLQRTSQKL-NRVSEWHA-V 284
+K K+ + LK + EE+ R + R ELE R +KL+ S L ++++E A +
Sbjct: 1013 EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR-RKLEGDSTDLSDQIAELQAQI 1071
Query: 285 RHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFI-TSLNEENKKL----I 339
LK++ + E +A LA+V + A ++ + ++R + T ++E + L
Sbjct: 1072 AELKMQLA------KKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERA 1125
Query: 340 LRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEK--LQRLAEMQRKKEEA 397
R K + E+L+ +K++ ++ L A E R E E L++ E + K EA
Sbjct: 1126 CRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEA 1185
Query: 398 QIRREEERKASSAAREARAIEQLRRKE---ERAK--AQQEEAELL--AQKLAERLNESEQ 450
QI+ ++ + + A +EQ +R + E+AK + E EL + L + +SE
Sbjct: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEH 1245
Query: 451 RRKIYLEQIRE 461
+RK Q++E
Sbjct: 1246 KRKKVEAQLQE 1256
Score = 50.8 bits (120), Expect = 2e-05
Identities = 96/451 (21%), Positives = 185/451 (40%), Gaps = 84/451 (18%)
Query: 139 KLLSLKDKAPT--EVINEKNPRSTDNLRRQMQLPEKD----KEKRSTSLGKSMNAWKEKR 192
KL ++D+ + E + E+ + NL +Q+ K+K +G A + KR
Sbjct: 1330 KLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKR 1389
Query: 193 NWE-DILSSPFRVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKK------- 244
+ D+ R+ +++ L + + L D L+ + ++++ S+L+K
Sbjct: 1390 RLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQ 1449
Query: 245 ---------------------EAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHA 283
EA EK +AL + LE QK + ++LN+
Sbjct: 1450 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL--ERLNKQFR--- 1504
Query: 284 VRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEENKKLILRQK 343
++ + M ++ +S HE + + RA ++ +V E++ T L E +L Q
Sbjct: 1505 ---TEMEDLMSSKDDVGKSVHEL---EKSNRALEQ--QVEEMK--TQLEELEDEL---QA 1551
Query: 344 LHGSELRRAEKLQVIKSKQKEDL-AREEAVLERRKLI-----------EAEKLQR-LAEM 390
++LR LQ +K++ + DL R+E E++K + E E+ QR +A
Sbjct: 1552 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMA 1611
Query: 391 QRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLAQKLAERLNESEQ 450
RKK E ++ E ++ AI+QLR+ + + K + + E L ++++
Sbjct: 1612 ARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKE 1671
Query: 451 RRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGIGS 510
K E L+++ + R + + +A + +S G G+
Sbjct: 1672 NEKKLKSMEAEMIQLQEELAAAER------------AKRQAQQERDELADEIANSSGKGA 1719
Query: 511 ITLQHSMKRRIKRIRQKLMALKYEFLEPPLG 541
+ L+ KRR+ + L+AL E LE G
Sbjct: 1720 LALEE--KRRL----EALIALLEEELEEEQG 1744
Score = 44.7 bits (104), Expect = 0.002
Identities = 81/440 (18%), Positives = 180/440 (40%), Gaps = 39/440 (8%)
Query: 103 ESLLTSEVDLAK-LPSLENSSALATAKV---KTHLGSGADKLLSLKDKAPTEVINEKNPR 158
E L++S+ D+ K + LE S+ +V KT L D+L + +D +N + +
Sbjct: 1508 EDLMSSKDDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1567
Query: 159 STDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGRKS 218
+ R +Q ++ E++ L + + + + E + S + + +K
Sbjct: 1568 A--QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDE---------RKQRSIAMAARKKL 1616
Query: 219 AERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQKLNRV 278
++ L + + K ++ ++ + + +R + R + L + + ++
Sbjct: 1617 EMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKENEKKL 1676
Query: 279 SEWHAVRHLKLREGMYARHQ---RSESRHEAFLAQVAKRAGDESSKVNEVR----FITSL 331
A ++L+E + A + +++ + ++A +G + + E R I L
Sbjct: 1677 KSMEA-EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEALIALL 1735
Query: 332 NEENKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQ 391
EE ++ +L L++A LQ+ + +L R A + E+ + E++
Sbjct: 1736 EEELEEEQGNTELINDRLKKAN-LQIDQINTDLNLERSHAQKNENARQQLERQNK--ELK 1792
Query: 392 RKKEEAQIRREEERKASSAAREARAI---EQLRRKEERAKAQQEEAELLAQKLAERLNES 448
K +E + + + KAS AA EA+ EQL + + +A ++ +KL + L +
Sbjct: 1793 AKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLLQV 1852
Query: 449 EQRRKIYLEQIRERANLRDQSSPLLRRSLNKDGQGRSTPNNSSDDSQTNIASGLGSSLGI 508
E R+ EQ +++A+ L+R L + + N S Q + ++
Sbjct: 1853 EDERR-NAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA--- 1908
Query: 509 GSITLQHSMKRRIKRIRQKL 528
+M R + ++ KL
Sbjct: 1909 ------DAMNREVSSLKNKL 1922
Score = 43.9 bits (102), Expect = 0.003
Identities = 62/274 (22%), Positives = 116/274 (41%), Gaps = 35/274 (12%)
Query: 243 KKEAEEKHARALRIRSELETERVQKLQRTSQKLNRVSEWHAVRHLKLREGMYARHQRSES 302
KK+ E+ L R E E ER Q LQ +K+ + + L+ E + Q +
Sbjct: 909 KKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQ-ELEEQLEEEESARQKLQLEKV 967
Query: 303 RHEAFLAQVAKRA---GDESSKVNEVR---------FITSLNEENKKLILRQKL---HGS 347
EA L ++ + D++ K+ + + F T L EE +K KL H +
Sbjct: 968 TTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEA 1027
Query: 348 ELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLA------EMQRKKEEAQIRR 401
+ E+ + KQ+++L + LE ++++ L +MQ K+E +++
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 402 EEERKASSAAREARAIEQLRRKEERAKAQQEEAEL------LAQKLAERLNESEQRRKIY 455
R AA++ A++++R E + QE+ E A+K L E + K
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKTE 1147
Query: 456 LEQI-------RERANLRDQSSPLLRRSLNKDGQ 482
LE +E + R+Q +L+++L + +
Sbjct: 1148 LEDTLDSTAAQQELRSKREQEVSILKKTLEDEAK 1181
Score = 41.2 bits (95), Expect = 0.017
Identities = 83/416 (19%), Positives = 165/416 (38%), Gaps = 64/416 (15%)
Query: 215 GRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETERVQKLQRTSQK 274
G + E L K S K+KK + L+ E + K + R+R+EL ++V KLQ
Sbjct: 1227 GELANEVKALLQGKGDSEHKRKKVEAQLQ-ELQVKFSEGERVRTEL-ADKVSKLQVELDS 1284
Query: 275 LNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
+ + + KL + A + + E L EE
Sbjct: 1285 VTGLLNQSDSKSSKLTKDFSALESQLQDTQEL------------------------LQEE 1320
Query: 335 NK-KLILRQKLHGSELRR---AEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEM 390
N+ KL L KL E + E+L+ + + K +L ++ A L + +K++
Sbjct: 1321 NRQKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGC 1380
Query: 391 QRKKEEAQIRREEERKASSAAREARAIEQLRRKEERAKAQQEEAELLA------------ 438
EEA+ R +++ + S E + + ++ + + QQE +LL
Sbjct: 1381 LETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNL 1440
Query: 439 ---QKLAERLNESEQRRKIYLEQIRERANL----RDQSSPLLRRSLNKDGQGRSTPNNSS 491
QK ++L E+ + R+RA ++ + L R+L + + ++ +
Sbjct: 1441 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLN 1500
Query: 492 DDSQTNIASGLGSSLGIGSITLQHSMKRRIKRIRQKL--MALKYEFLEPPL-GGESAGIG 548
+T + + S +G H +++ + + Q++ M + E LE L E A +
Sbjct: 1501 KQFRTEMEDLMSSKDDVGKSV--HELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLR 1558
Query: 549 YRVAVGAARAKVGRWLQELQRLRQARKEGATSIGLIISEMIKYLEGKDPELQASRQ 604
V + A +A+ R LQ + +K+ ++++ + + EL+ R+
Sbjct: 1559 LEVNLQAMKAQFERDLQGRDEQSEEKKK----------QLVRQVREMEAELEDERK 1604
Score = 41.2 bits (95), Expect = 0.017
Identities = 84/423 (19%), Positives = 182/423 (42%), Gaps = 52/423 (12%)
Query: 144 KDKAPTEVINEKNPRSTDNLRRQMQLPEKDKEKRSTSLGKSMNAWKEKRNWE-DILSSPF 202
K K+ ++ N+ TD L +++ EK +++ K +R E D
Sbjct: 1014 KSKSLAKLKNKHEAMITD-LEERLRREEKQRQELE----------KTRRKLEGDSTDLSD 1062
Query: 203 RVSSRMSYSPSLGRKSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELET 262
+++ + L + A++ L L E++ + K+ E + ++ +LE+
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLES 1122
Query: 263 ERVQKLQRTSQKLNRVSEWHAVR-HLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSK 321
ER + + QK + E A++ L+ A Q S+ E ++ + K+ ++ +K
Sbjct: 1123 ERACRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVS-ILKKTLEDEAK 1181
Query: 322 VNEVRFITSLNEENKKLI--LRQKLHGSELRRA--EKLQVIKSKQKEDLAREEAVL---- 373
+E + I + +++ + + L ++L ++ +A EK + ++ +LA E L
Sbjct: 1182 THEAQ-IQEMRQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELANEVKALLQGK 1240
Query: 374 ----ERRKLIEAEKLQRLAEMQRKKEEAQ-IRREEERKASSAAREARAIEQLRRKEERAK 428
+RK +EA+ L E+Q K E + +R E K S E ++ L + +
Sbjct: 1241 GDSEHKRKKVEAQ----LQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKS 1296
Query: 429 AQ------------QEEAELLAQKLAERLNESEQRRKIYLEQIRERANLRDQSSPLLRRS 476
++ Q+ ELL ++ ++L+ S + +++ E+ R L ++ +R+
Sbjct: 1297 SKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQLEEEEEE-AKRN 1355
Query: 477 LNKDGQGRSTPNNSSDDSQTNIASGLG--SSLGIGSITLQHSMKRRIKRIRQKLMALKYE 534
L K +T + D + + G+G + LQ ++ +R+ +K+ A Y+
Sbjct: 1356 LEKQ---IATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAA--YD 1410
Query: 535 FLE 537
LE
Sbjct: 1411 KLE 1413
Score = 40.4 bits (93), Expect = 0.029
Identities = 68/311 (21%), Positives = 130/311 (40%), Gaps = 30/311 (9%)
Query: 251 ARALRIRSELETERVQKLQRTSQKLNRVSEWHAVR-HLKLREGMYA-RHQRSESRHEAFL 308
AR + + + ++ LQR R+ W R K++ + + RH+ EA L
Sbjct: 795 ARKAFAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAEL 854
Query: 309 AQVAKRAGDESSKVNEVRFITSLNEENKKLILRQKLHGSEL-RRAEKLQVIKSKQKEDLA 367
+V ++ +++ E+ + S K + Q +EL AE+L+ + +K++L
Sbjct: 855 TKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAKTELCAEAEELRARLTAKKQELE 914
Query: 368 REEAVLERRKLIEAEKLQRLAEMQRKKEEAQIRREEERKASSAAREARAIEQLRRKEERA 427
LE R E E+ Q L ++K ++ EE+ + +AR+ +E++ + +
Sbjct: 915 EICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 428 KAQQE-------------EAELLAQKLAE----RLNESEQRRKIYLEQIRERANLRDQSS 470
K +++ E +LL ++AE + E E+ + + + + A + D
Sbjct: 975 KLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 471 PLLRRSLNK---DGQGRSTPNNSSD------DSQTNIASGLGSSLGIGSITLQHSMKRRI 521
L R + + R +S+D + Q IA L L LQ ++ R
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE-LKMQLAKKEEELQAALARVE 1093
Query: 522 KRIRQKLMALK 532
+ QK MALK
Sbjct: 1094 EEAAQKNMALK 1104
Score = 40.0 bits (92), Expect = 0.038
Identities = 60/272 (22%), Positives = 117/272 (42%), Gaps = 43/272 (15%)
Query: 159 STDNLRRQMQLPEKDK--EKRSTSLGKSMNAWKEKRNWEDILSSPFRVSSRMSYSPSLGR 216
+ + +RQ Q E+D+ ++ + S GK A +EKR E +++
Sbjct: 1692 AAERAKRQAQ-QERDELADEIANSSGKGALALEEKRRLEALIA----------------- 1733
Query: 217 KSAERVRTLHDKLMSPEKKKKTTSDLKKEAEEKHARALRIRSELETER--VQKLQRTSQK 274
L ++L + + +D K+A + + +I ++L ER QK + Q+
Sbjct: 1734 -------LLEEELEEEQGNTELINDRLKKA---NLQIDQINTDLNLERSHAQKNENARQQ 1783
Query: 275 LNRVSEWHAVRHLKLREGMYARHQRSESRHEAFLAQVAKRAGDESSKVNEVRFITSLNEE 334
L R ++ + ++ + ++++ S + EA +AQ+ ++ +E+ + E+
Sbjct: 1784 LERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEK 1843
Query: 335 NKKLILRQKLHGSELRRAEKLQVIKSKQKEDLAREEAVLERRKLIEAEKLQRLAEMQRKK 394
K +L Q E R AE+ K + D A +R+L EAE+ + A R+K
Sbjct: 1844 KLKDVLLQV--EDERRNAEQF-----KDQADKASTRLKQLKRQLEEAEEEAQRANASRRK 1896
Query: 395 EEAQIRREEERKASSAAREARAIEQLRRKEER 426
++RE E +A R + L+ K R
Sbjct: 1897 ----LQRELEDATETADAMNREVSSLKNKLRR 1924
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 128,850,181
Number of Sequences: 164201
Number of extensions: 5341613
Number of successful extensions: 30811
Number of sequences better than 10.0: 1495
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 1213
Number of HSP's that attempted gapping in prelim test: 19163
Number of HSP's gapped (non-prelim): 5359
length of query: 1215
length of database: 59,974,054
effective HSP length: 122
effective length of query: 1093
effective length of database: 39,941,532
effective search space: 43656094476
effective search space used: 43656094476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 72 (32.3 bits)
Lotus: description of TM0087.21