BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0087.18
(433 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
FMO3_HUMAN (P31513) Dimethylaniline monooxygenase [N-oxide-formi... 110 9e-24
FMO3_PANTR (Q7YS44) Dimethylaniline monooxygenase [N-oxide-formi... 109 1e-23
FMO2_HUMAN (Q99518) Dimethylaniline monooxygenase [N-oxide-formi... 109 1e-23
FMO2_GORGO (Q8HZ69) Dimethylaniline monooxygenase [N-oxide-formi... 108 3e-23
FMO3_MACMU (Q8SPQ7) Dimethylaniline monooxygenase [N-oxide-formi... 108 3e-23
FMO2_PANTR (Q8HZ70) Dimethylaniline monooxygenase [N-oxide-formi... 108 3e-23
FMO6_HUMAN (O60774) Putative dimethylaniline monooxygenase [N-ox... 107 8e-23
FMO3_MOUSE (P97501) Dimethylaniline monooxygenase [N-oxide-formi... 105 2e-22
FMO2_MACMU (Q28505) Dimethylaniline monooxygenase [N-oxide-formi... 105 3e-22
FMO1_YEAST (P38866) Thiol-specific monooxygenase (EC 1.14.13.-) ... 105 3e-22
FMO2_CAVPO (P36366) Dimethylaniline monooxygenase [N-oxide-formi... 104 5e-22
FMO3_RABIT (P32417) Dimethylaniline monooxygenase [N-oxide-formi... 103 7e-22
FMO1_CANFA (Q95LA2) Dimethylaniline monooxygenase [N-oxide-formi... 102 1e-21
FMO3_CANFA (Q95LA1) Dimethylaniline monooxygenase [N-oxide-formi... 102 2e-21
FMO2_RABIT (P17635) Dimethylaniline monooxygenase [N-oxide-formi... 102 2e-21
FMO1_RABIT (P17636) Dimethylaniline monooxygenase [N-oxide-formi... 101 4e-21
FMO1_MOUSE (P50285) Dimethylaniline monooxygenase [N-oxide-formi... 100 1e-20
FMO5_CAVPO (P49109) Dimethylaniline monooxygenase [N-oxide-formi... 99 2e-20
FMO5_HUMAN (P49326) Dimethylaniline monooxygenase [N-oxide-formi... 99 3e-20
FMO5_RABIT (Q04799) Dimethylaniline monooxygenase [N-oxide-formi... 98 5e-20
>FMO3_HUMAN (P31513) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
(FMO form 2) (FMO II)
Length = 531
Score = 110 bits (274), Expect = 9e-24
Identities = 81/237 (34%), Positives = 126/237 (52%), Gaps = 26/237 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL + R EG + FE+++DIGG W ++ + + +
Sbjct: 2 KKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAE-----------EGR 50
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFPF D F + ++ Y+ F + L + I+F
Sbjct: 51 ASIYKSVFSNSSKEMMCFPDFPF----PDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFK 106
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLP--C 186
T +V +N + F+ +W V + E DG E VFDAV+V SGH+ +P LP
Sbjct: 107 T---FVSSVNKHPDFATTG--QWDVTT---ERDGKKESAVFDAVMVCSGHHVYPNLPKES 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G++ +K K HS Y+ P F + V+VVG SG +I+ +L + A++V +SS S
Sbjct: 159 FPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRS 215
Score = 35.0 bits (79), Expect = 0.38
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 286 LYEHTFPPSLAPS-LSFMG-IPSKVLGPHFFESQAKWIAQLLSGKKILPSFEEMMKSIKE 343
L++ FPP L S ++ +G + S + Q++W AQ++ G LPS E+MM I E
Sbjct: 351 LFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINE 410
>FMO3_PANTR (Q7YS44) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 531
Score = 109 bits (273), Expect = 1e-23
Identities = 81/237 (34%), Positives = 125/237 (52%), Gaps = 26/237 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL + R EG + FE+++DIGG W ++ + + +
Sbjct: 2 KKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAE-----------EGR 50
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFPF D F + ++ Y+ F + L + I+F
Sbjct: 51 ASIYKSVFSNSSKEMMCFPDFPF----PDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFK 106
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLP--C 186
T +V +N F+ +W V + E DG E VFDAV+V SGH+ +P LP
Sbjct: 107 T---FVSSVNKRPDFATTG--QWDVTT---ERDGKKESAVFDAVMVCSGHHVYPNLPKES 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G++ +K K HS Y+ P F + V+VVG SG +I+ +L + A++V +SS S
Sbjct: 159 FPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRS 215
Score = 35.0 bits (79), Expect = 0.38
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 286 LYEHTFPPSLAPS-LSFMG-IPSKVLGPHFFESQAKWIAQLLSGKKILPSFEEMMKSIKE 343
L++ FPP L S ++ +G + S + Q++W AQ++ G LPS E+MM I E
Sbjct: 351 LFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINE 410
>FMO2_HUMAN (Q99518) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 109 bits (273), Expect = 1e-23
Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + NV+
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVE-----------DG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYQSVVTNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V FS + K V +S KE VFDAV+V SGH+ P +P
Sbjct: 106 QTTVLSVRKC---PDFSSSGQWKVVTQSNGKEQSA----VFDAVMVCSGHHILPHIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
GM+ +K + HS Y+ P F + ++V+G SG +I+++L K A +V +S+
Sbjct: 159 FPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFIST 213
Score = 31.6 bits (70), Expect = 4.2
Identities = 25/67 (37%), Positives = 37/67 (54%), Gaps = 5/67 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLAPS-LSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
+E+N V LY++ FP L S L+ +G+ + LG F E QA+W+ ++ G LPS
Sbjct: 344 VENNMVS-LYKYIFPAHLDKSTLACIGL-IQPLGSIFPTAELQARWVTRVFKGLCSLPSE 401
Query: 335 EEMMKSI 341
MM I
Sbjct: 402 RTMMMDI 408
>FMO2_GORGO (Q8HZ69) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 108 bits (270), Expect = 3e-23
Identities = 78/235 (33%), Positives = 120/235 (50%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + NV+
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVE-----------DG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYQSVVTNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V FS + K V +S KE + VFDAV+V SGH+ P +P
Sbjct: 106 QTTVLSVRKC---PDFSSSGQWKVVTQSNGKEQNA----VFDAVMVCSGHHILPHIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P F + ++V+G SG +I+++L K A +V +S+
Sbjct: 159 FPGIERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFIST 213
Score = 31.6 bits (70), Expect = 4.2
Identities = 25/67 (37%), Positives = 37/67 (54%), Gaps = 5/67 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLAPS-LSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
+E+N V LY++ FP L S L+ +G+ + LG F E QA+W+ ++ G LPS
Sbjct: 344 VENNMVS-LYKYIFPAHLDKSTLACIGL-IQPLGSIFPTAELQARWVTRVFKGLCSLPSE 401
Query: 335 EEMMKSI 341
MM I
Sbjct: 402 RTMMMDI 408
>FMO3_MACMU (Q8SPQ7) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 531
Score = 108 bits (269), Expect = 3e-23
Identities = 81/237 (34%), Positives = 124/237 (52%), Gaps = 26/237 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL + R EG + FE+++DIGG W ++ + + +
Sbjct: 2 KKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAE-----------EGR 50
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFP+ D F + ++ YL F + L + I+F
Sbjct: 51 ASIYKSVFTNSSKEMMCFPDFPY----PDDFPNFMHNSKIQEYLTAFAKEKSLLKYIQFK 106
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLP--C 186
T +V +N F+ +W V + E DG E VFDAV+V SGH+ +P LP
Sbjct: 107 T---FVSSVNKRPDFATTG--QWDVTT---ERDGKRESAVFDAVMVCSGHHVYPNLPKES 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G++ +K K HS Y+ P F + V+VVG SG +I+ +L A++V +SS S
Sbjct: 159 FPGLNHFKGKCFHSRDYKEPGVFKGKRVLVVGLGNSGCDIATELSHTAEQVVISSRS 215
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/60 (33%), Positives = 33/60 (54%), Gaps = 2/60 (3%)
Query: 286 LYEHTFPPSLAPS-LSFMG-IPSKVLGPHFFESQAKWIAQLLSGKKILPSFEEMMKSIKE 343
L++ FPP L S ++ +G + S + Q++W A+++ G LPS E+MM I E
Sbjct: 351 LFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAARVIKGTCTLPSMEDMMNDINE 410
>FMO2_PANTR (Q8HZ70) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 108 bits (269), Expect = 3e-23
Identities = 78/235 (33%), Positives = 119/235 (50%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + NV+
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVE-----------DG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYQSVITNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V FS + K V +S KE VFDAV+V SGH+ P +P
Sbjct: 106 QTTVLSVRKC---PDFSSSGQWKVVTQSNGKEQSA----VFDAVMVCSGHHILPHIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P F + ++V+G SG +I+++L K A +V +S+
Sbjct: 159 FPGIERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFIST 213
Score = 31.6 bits (70), Expect = 4.2
Identities = 25/67 (37%), Positives = 37/67 (54%), Gaps = 5/67 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLAPS-LSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
+E+N V LY++ FP L S L+ +G+ + LG F E QA+W+ ++ G LPS
Sbjct: 344 VENNMVS-LYKYIFPAHLDKSTLACIGL-IQPLGSIFPTAELQARWVTRVFKGLCSLPSE 401
Query: 335 EEMMKSI 341
MM I
Sbjct: 402 RTMMMDI 408
>FMO6_HUMAN (O60774) Putative dimethylaniline monooxygenase
[N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing
monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6)
Length = 539
Score = 107 bits (266), Expect = 8e-23
Identities = 76/239 (31%), Positives = 126/239 (51%), Gaps = 26/239 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
SK V +IGAG SGL A EG + FE++ D+GG W ++ + + +
Sbjct: 2 SKRVGIIGAGVSGLAAIWCCLEEGLEPTCFERSDDVGGLWKFSDHTE-----------EG 50
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ S +E+M F DFP+ D + H +L Y+ + + L I+F
Sbjct: 51 RASIYQSVFTNSSKEMMCFPDFPY----PDDYPNYIHHSKLQEYIKTYAQKKDLLRYIQF 106
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLPC- 186
T V + + +G +WVV + E DG E +FDAV++ SGH+ +P LP
Sbjct: 107 ETLVSGIKKCP-SFLVTG----QWVVVT---EKDGKQESTIFDAVMICSGHHVYPNLPTD 158
Query: 187 -IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNSA 244
G+D ++ +HS Y+ P+ F + V+V+G SG +I+++L ++A +V +S+ SA
Sbjct: 159 SFPGLDQFRGNYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSA 217
>FMO3_MOUSE (P97501) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 534
Score = 105 bits (263), Expect = 2e-22
Identities = 78/237 (32%), Positives = 122/237 (50%), Gaps = 26/237 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL A R EG + FE++ D+GG W ++ +++ +
Sbjct: 3 KKVAIIGAGVSGLAAIRSCLEEGLEPTCFERSDDVGGLWKFSDHIE-----------EGR 51
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFP+ D F H +L Y+ F + L + I+F
Sbjct: 52 ASIYQSVFTNSSKEMMCFPDFPY----PDDFPNFMHHSKLQEYITSFAKEKNLLKYIQFE 107
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVE-EVFDAVVVASGHYSHPKLP--C 186
T V + N + +G KW V + E G E VFDA ++ SGH+ P +P
Sbjct: 108 TPVTSINKCP-NFSTTG----KWEVTT---EKHGKKETAVFDATMICSGHHIFPHVPKDS 159
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G++ +K K HS Y+ P + + V+V+G SG +I+ +L VA++V +SS S
Sbjct: 160 FPGLNRFKGKCFHSRDYKEPGIWKGKRVLVIGLGNSGCDIAAELSHVAQKVTISSRS 216
Score = 37.4 bits (85), Expect = 0.076
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 286 LYEHTFPPSLA-PSLSFMGIPSKVLGP-HFFESQAKWIAQLLSGKKILPSFEEMMKSIKE 343
LY+ FPP L P+++ +G+ + + QA+W AQ++ G LPS +MM I E
Sbjct: 352 LYKGVFPPQLEKPTMAVIGLVQSLGATIPITDLQARWAAQVIKGTCTLPSVNDMMDDIDE 411
>FMO2_MACMU (Q28505) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 105 bits (261), Expect = 3e-22
Identities = 77/235 (32%), Positives = 118/235 (49%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + K V
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRF-----------KEKVEDG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYQSVVTNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V FS + K V +S KE VFDAV+V +GH+ P +P
Sbjct: 106 QTTVLSVRKC---PDFSSSGQWKVVTQSNGKEQSA----VFDAVMVCTGHHFLPHIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P F + ++V+G SG +I+++L K A +V +S+
Sbjct: 159 FPGIERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKSAAQVFIST 213
>FMO1_YEAST (P38866) Thiol-specific monooxygenase (EC 1.14.13.-)
(Flavin-dependent monooxygenase)
Length = 432
Score = 105 bits (261), Expect = 3e-22
Identities = 84/287 (29%), Positives = 136/287 (47%), Gaps = 42/287 (14%)
Query: 5 TNQNSKNVCVIGAGPSGLVATRELKRE--GHKVVVFEQNHDIGGQWLYNPNVQCEDPLGK 62
T + K + +IG GP GL A R + ++ +F +++DIGG W Y P + + +
Sbjct: 2 TVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHY-PEQKSDGRV-- 58
Query: 63 NPVLKVHSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGL 122
+Y+ L +++M F+ FPF ++ +P R + YL + + F
Sbjct: 59 ---------MYDHLETNISKKLMQFSGFPF----EENVPLYPSRRNIWEYLKAYYKTFIA 105
Query: 123 RE---VIRFNTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHY 179
+ I F+T V Y+ N + D+L+ +SD FD V+VASGHY
Sbjct: 106 NKDAISIHFSTEVTYLKKKNSQWEITSKDELRTT------KSD------FDFVIVASGHY 153
Query: 180 SHPKLPC-IQGMDTW--KRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKE 236
S PKLP I G+D W + HS ++ + +++V+VVGN SGQ+I+ L VAK+
Sbjct: 154 SVPKLPTNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKK 213
Query: 237 VHLSSNSAYISEGLSKVIHKYQNFHLHPQIDNLQEDGREWFIEDNRV 283
V+ S ++ +K+I Q ID+ R + D RV
Sbjct: 214 VYNSIKEPASNQLKAKLIETVQT------IDSADWKNRSVTLSDGRV 254
>FMO2_CAVPO (P36366) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 104 bits (259), Expect = 5e-22
Identities = 78/247 (31%), Positives = 125/247 (50%), Gaps = 25/247 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + NV+
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVE-----------DG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYKSVITNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRLFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V + FS + + V +S KE VFDAV+V SGH+ P +P
Sbjct: 106 QTTVLTV---KKHPDFSSSGQWEVVTQSDGKEQSA----VFDAVMVCSGHHILPHIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS-NSAY 245
G++ +K + HS Y+ P F + ++V+G S +I+ +L K A +V +S+ N ++
Sbjct: 159 FPGIERFKGQYFHSRQYKHPAGFEGKRILVIGIGNSASDIASELSKNAAQVFISTRNGSW 218
Query: 246 ISEGLSK 252
+ +S+
Sbjct: 219 VMSRISE 225
Score = 38.1 bits (87), Expect = 0.044
Identities = 28/67 (41%), Positives = 39/67 (57%), Gaps = 5/67 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLA-PSLSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
IE N V LY++ FPP L P+L+ MG+ + LG F E QA+W ++ G LPS
Sbjct: 344 IEHNMVS-LYKYMFPPQLEKPTLTCMGL-IQPLGSIFPTVELQARWATRVFKGLCHLPSE 401
Query: 335 EEMMKSI 341
+ MM+ I
Sbjct: 402 KTMMEDI 408
>FMO3_RABIT (P32417) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
(FMO 1D1) (FMO form 2) (FMO II)
Length = 530
Score = 103 bits (258), Expect = 7e-22
Identities = 79/239 (33%), Positives = 120/239 (50%), Gaps = 30/239 (12%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL + R EG + FE + DIGG W ++ + + +
Sbjct: 2 KKVAIIGAGISGLASIRSCLEEGLEPTCFEMSDDIGGLWKFSDHAE-----------EGR 50
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFPF D F + +L Y+ F L + I+F
Sbjct: 51 ASIYQSVFTNSSKEMMCFPDFPF----PDDFPNFMHNSKLQEYITTFAREKNLLKYIQFK 106
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVV---RSKEKESDGVVEEVFDAVVVASGHYSHPKLP- 185
T V + + FS +W V R+ +KE+ VFDAV++ SGH+ +P LP
Sbjct: 107 T---LVSSIKKHPDFSVTG--QWYVSTERNGKKET-----AVFDAVMICSGHHVYPNLPK 156
Query: 186 -CIQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G+ +K K HS Y+ P F + V+V+G SG +I+ +L A++V +SS S
Sbjct: 157 DSFPGLKHFKGKSFHSREYKEPGIFKGKRVLVIGLGNSGCDIATELSHTAEQVVISSRS 215
Score = 36.2 bits (82), Expect = 0.17
Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 5/68 (7%)
Query: 279 EDNRVGPLYEHTFPPSLA-PSLSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSFE 335
E+N+V L++ FPP L P+++ +G+ LG + QA+W AQ++ G LP +
Sbjct: 345 ENNKV-TLFKGIFPPQLEKPTMAVIGLVQS-LGAAIPTTDLQARWAAQVIKGTCTLPPVK 402
Query: 336 EMMKSIKE 343
+MM I E
Sbjct: 403 DMMNDIHE 410
>FMO1_CANFA (Q95LA2) Dimethylaniline monooxygenase [N-oxide-forming]
1 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1)
Length = 531
Score = 102 bits (255), Expect = 1e-21
Identities = 70/235 (29%), Positives = 123/235 (51%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V ++GAG SGL + + EG + FE++ D+GG W + +V+ +
Sbjct: 1 AKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVE-----------EG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+S+Y+S+ S +E+ ++DFPF D + + + L YL + F L + IRF
Sbjct: 50 RASLYKSVVSNSCKEMSCYSDFPF----PEDYPNYVPNSQFLEYLKMYANRFSLLKCIRF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T+V V F+ + V + + K+ + FDAV+V +G ++P LP C
Sbjct: 106 KTKVCKVTKCP---DFTVTGQWEVVTQHEGKQESAI----FDAVMVCTGFLTNPHLPLDC 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++T+K + HS Y+ P F + V+V+G SG +I+++ ++AK+V LS+
Sbjct: 159 FPGINTFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVETSRLAKKVFLST 213
>FMO3_CANFA (Q95LA1) Dimethylaniline monooxygenase [N-oxide-forming]
3 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3)
Length = 531
Score = 102 bits (254), Expect = 2e-21
Identities = 78/237 (32%), Positives = 121/237 (50%), Gaps = 26/237 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V +IGAG SGL + R EG + FE++ DIGG W ++ + + +
Sbjct: 2 KRVAIIGAGVSGLASIRSCLEEGLEPTCFERSEDIGGLWKFSEHAE-----------EGR 50
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ S +E+M F DFP+ D F + +L Y+ F + L + I+F
Sbjct: 51 ASIYQSVFTNSSKEMMCFPDFPY----PDDFPNFMHNSKLQEYITVFSKEKNLLKYIQFK 106
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLP--C 186
T V +N FS + +W + + E DG E FDAV++ SGH+ +P LP
Sbjct: 107 T---LVCSVNKRPDFSVSG--QWDITT---ERDGKRESATFDAVLICSGHHVYPNLPEES 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSSNS 243
G+ +K K HS Y+ P F + V+V+G SG +I+ +L A++V +SS S
Sbjct: 159 FPGLKLFKGKCFHSREYKEPGIFKGKRVLVIGLGNSGCDIATELSHTAEQVIISSRS 215
Score = 31.6 bits (70), Expect = 4.2
Identities = 20/59 (33%), Positives = 31/59 (51%), Gaps = 4/59 (6%)
Query: 286 LYEHTFPPSLA-PSLSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSFEEMMKSI 341
L++ FPP L P+++ +G LG + QA+W Q++ G LPS +MM I
Sbjct: 351 LFKGIFPPKLEKPTMAVIGFVQS-LGATIPTTDLQARWAVQVIKGTCTLPSVTDMMNDI 408
>FMO2_RABIT (P17635) Dimethylaniline monooxygenase [N-oxide-forming]
2 (EC 1.14.13.8) (Pulmonary flavin-containing
monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2)
(FMO 1B1)
Length = 534
Score = 102 bits (254), Expect = 2e-21
Identities = 73/235 (31%), Positives = 118/235 (50%), Gaps = 24/235 (10%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V VIGAG SGL++ + EG + FE+ DIGG W + NV+
Sbjct: 1 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVE-----------DG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+SIY+S+ + +E+ F+DFP D F + +LL Y F + F L + I+F
Sbjct: 50 RASIYQSVITNTSKEMSCFSDFPM----PEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQF 105
Query: 129 NTRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--C 186
T V V F+ + + V +S K+ VFDAV+V SGH+ P +P
Sbjct: 106 QTTVISV---KKRPDFASSGQWEVVTQSNSKQQSA----VFDAVMVCSGHHILPNIPLKS 158
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P + ++V+G S +I+++L K A +V++S+
Sbjct: 159 FPGIEKFKGQYFHSRQYKHPAGLEGKRILVIGIGNSASDIAVELSKKAAQVYIST 213
Score = 37.4 bits (85), Expect = 0.076
Identities = 28/67 (41%), Positives = 37/67 (54%), Gaps = 5/67 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLAPS-LSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
IEDN V LY++ FPP L S + +G+ + LG F E QA+W ++ G LPS
Sbjct: 344 IEDNMVS-LYKYMFPPQLEKSTFACLGL-IQPLGSIFPTVELQARWATRVFKGLCSLPSK 401
Query: 335 EEMMKSI 341
E MM I
Sbjct: 402 ETMMADI 408
>FMO1_RABIT (P17636) Dimethylaniline monooxygenase [N-oxide-forming]
1 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1)
(FMO 1A1) (FMO form 1)
Length = 534
Score = 101 bits (251), Expect = 4e-21
Identities = 71/236 (30%), Positives = 125/236 (52%), Gaps = 26/236 (11%)
Query: 9 SKNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKV 68
+K V ++GAG SGL + + EG + FE++ D+GG W + +V+ +
Sbjct: 1 AKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVE-----------EG 49
Query: 69 HSSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRF 128
+S+Y+S+ S +E+ ++DFPF D + + + L YL + + F L + I+F
Sbjct: 50 RASLYKSVVSNSCKEMSCYSDFPF----PEDYPNYVPNSQFLDYLKMYADRFSLLKSIQF 105
Query: 129 NTRVEYVGPL-NYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP-- 185
T V + ++N SG ++ + K++ + +FDAV+V +G ++P LP
Sbjct: 106 KTTVFSITKCQDFN--VSGQWEVVTLHEGKQESA------IFDAVMVCTGFLTNPHLPLG 157
Query: 186 CIQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
C G+ T+K + HS Y+ P F + V+VVG SG +I+++ VAK+V LS+
Sbjct: 158 CFPGIKTFKGQYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHVAKKVFLST 213
>FMO1_MOUSE (P50285) Dimethylaniline monooxygenase [N-oxide-forming]
1 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1)
Length = 532
Score = 99.8 bits (247), Expect = 1e-20
Identities = 73/234 (31%), Positives = 119/234 (50%), Gaps = 24/234 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V ++GAG SGL + + EG + FE++ D+GG W + +V+ +
Sbjct: 3 KRVAIVGAGVSGLASIKCCLEEGLEPTCFERSSDLGGLWRFTEHVE-----------EGR 51
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+S+Y+S+ S RE+ + DFPF D F + L YL + F L+ I FN
Sbjct: 52 ASLYKSVVSNSSREMSCYPDFPF----PEDYPNFVPNSLFLEYLKLYSTQFNLQRCIYFN 107
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLP--CI 187
T+V + + A SG ++ V K+ + +FDAV+V +G ++P LP
Sbjct: 108 TKVCSI-TKRPDFAVSGQWEVVTVTNGKQNSA------IFDAVMVCTGFLTNPHLPLDSF 160
Query: 188 QGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G+ T+K + HS Y+ P F + V+VVG SG +I+++ +AK+V LS+
Sbjct: 161 PGILTFKGEYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLST 214
Score = 37.4 bits (85), Expect = 0.076
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 5/69 (7%)
Query: 278 IEDNRVGPLYEHTFPPSLA-PSLSFMGIPSKVLGPHF--FESQAKWIAQLLSGKKILPSF 334
+ED + LY++ FP L P+L+ +G+ K LG E+QA+W+ Q+L G LP
Sbjct: 345 VEDGQAS-LYKYIFPAHLPKPTLAVIGL-IKPLGSMVPTGETQARWVVQVLKGATTLPPP 402
Query: 335 EEMMKSIKE 343
MM+ + E
Sbjct: 403 SVMMEEVNE 411
>FMO5_CAVPO (P49109) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
Length = 532
Score = 99.4 bits (246), Expect = 2e-20
Identities = 69/234 (29%), Positives = 121/234 (51%), Gaps = 24/234 (10%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K + VIG G SGL + + EG + V FE++ DIGG W + N + +
Sbjct: 3 KRIAVIGGGVSGLSSIKCCLEEGLEPVCFERSADIGGLWRFQENPE-----------EGR 51
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ + + +E+M F+D+P F + +L Y + + FGL + I+F
Sbjct: 52 ASIYKSVIINTSKEMMCFSDYPI----PDHYPNFMHNSHVLEYFRMYAKEFGLLKYIQFK 107
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEEVFDAVVVASGHYSHPKLPC--I 187
T V N + +W V ++ + V +VFDAV+V +GH+++ LP
Sbjct: 108 TTV-----CNVKKRPDFSTSGQWEVVTEHEGKTKV--DVFDAVMVCTGHHTNAHLPLESF 160
Query: 188 QGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P+ F + VV++G SG ++++++ AK+V LS+
Sbjct: 161 PGIEKFKGQYFHSRDYKNPEAFTGKRVVIIGIGNSGGDLAVEISHTAKQVFLST 214
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 16/93 (17%)
Query: 277 FIED------NRVGPLYEHTFPPSLA-PSLSFMGI--PSKVLGPHFFESQAKWIAQLLSG 327
F+ED N+V LY+ FPP+L P+L+ +G+ P + P E Q +W Q+ G
Sbjct: 337 FLEDSVKVVKNKVS-LYKKVFPPNLERPTLAIIGLIQPLGAIMP-ISELQGRWAVQVFKG 394
Query: 328 KKILPSFEEMMKSIKELYHSREVANVPKRYTHS 360
K LPS EMM I ++ + KRY S
Sbjct: 395 LKTLPSQSEMMAEI-----TKAQEEIAKRYVDS 422
>FMO5_HUMAN (P49326) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
Length = 532
Score = 98.6 bits (244), Expect = 3e-20
Identities = 73/235 (31%), Positives = 124/235 (52%), Gaps = 26/235 (11%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K + VIG G SGL + + EG + V FE+ DIGG W + N + +
Sbjct: 3 KRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPE-----------EGR 51
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ + + +E+M F+D+P F + ++L Y + + F L + IRF
Sbjct: 52 ASIYKSVIINTSKEMMCFSDYPI----PDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFK 107
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVE-EVFDAVVVASGHYSHPKLPC-- 186
T V V + A SG +W V + ES+G E VFD V+V +GH+++ LP
Sbjct: 108 TTVCSVKK-QPDFATSG----QWEVVT---ESEGKKEMNVFDGVMVCTGHHTNAHLPLES 159
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + HS Y+ P+ F + V+++G SG ++++++ + AK+V LS+
Sbjct: 160 FPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLST 214
Score = 44.3 bits (103), Expect = 6e-04
Identities = 35/104 (33%), Positives = 50/104 (47%), Gaps = 16/104 (15%)
Query: 277 FIED------NRVGPLYEHTFPPSLA-PSLSFMGI--PSKVLGPHFFESQAKWIAQLLSG 327
F+ED N++ LY+ FPP+L P+L+ +G+ P + P E Q +W Q+ G
Sbjct: 337 FLEDSVKVVKNKIS-LYKKVFPPNLERPTLAIIGLIQPLGAIMP-ISELQGRWATQVFKG 394
Query: 328 KKILPSFEEMMKSIKELYHSREVANVPKRYTHSIADNDGFEYFD 371
K LPS EMM I S+ + KRY S +Y D
Sbjct: 395 LKTLPSQSEMMAEI-----SKAQEEIDKRYVESQRHTIQGDYID 433
>FMO5_RABIT (Q04799) Dimethylaniline monooxygenase [N-oxide-forming]
5 (EC 1.14.13.8) (Hepatic flavin-containing
monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5)
(FMO 1C1) (FMO form 3)
Length = 532
Score = 97.8 bits (242), Expect = 5e-20
Identities = 73/235 (31%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 10 KNVCVIGAGPSGLVATRELKREGHKVVVFEQNHDIGGQWLYNPNVQCEDPLGKNPVLKVH 69
K V VIGAG SGL + EG + V FE+ DIGG W + + +
Sbjct: 3 KRVAVIGAGASGLACIKCCLEEGLEPVCFERTDDIGGLWRFQESPD-----------EGR 51
Query: 70 SSIYESLRLMSPREIMGFTDFPFLVKKGRDMRRFPGHRELLFYLNDFCEWFGLREVIRFN 129
+SIY+S+ + + +E+M F+D+P F + ++L Y + + FGL + I+F
Sbjct: 52 ASIYKSVIINTSKEMMCFSDYPI----PDHFPNFMHNSQVLEYFRMYAKEFGLLKYIQFK 107
Query: 130 TRVEYVGPLNYNGAFSGNDDLKWVVRSKEKESDGVVEE-VFDAVVVASGHYSHPKLPC-- 186
T V V FS + +W V + E +G E VFD V+V +GH++ LP
Sbjct: 108 TTVCSV---KKRPDFSTSG--QWEVLT---ECEGKKESAVFDGVLVCTGHHTSAHLPLES 159
Query: 187 IQGMDTWKRKQMHSHIYRTPQPFGKEIVVVVGNSFSGQEISMDLVKVAKEVHLSS 241
G++ +K + +HS Y+ P+ F + V+V+G SG ++++++ AK+V LS+
Sbjct: 160 FPGIEKFKGQYLHSRDYKNPEKFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLST 214
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 277 FIED------NRVGPLYEHTFPPSLA-PSLSFMGI--PSKVLGPHFFESQAKWIAQLLSG 327
F+ED N+V LY+ FPP+L P+L+ +G+ P + P E QA+W + G
Sbjct: 337 FLEDSVKVVKNKVS-LYKKVFPPNLEKPTLAIIGLIQPLGAIMP-ISELQARWATLVFKG 394
Query: 328 KKILPSFEEMMKSIKELYHSREVANVPKRYTHS---IADNDGFEYFDKYGDNAG 378
K LPS EMM I ++ + KRY S D E ++ D G
Sbjct: 395 LKTLPSQSEMMTEISQVQE-----KMAKRYVESQRHTIQGDYIETMEEIADLVG 443
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.138 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,485,942
Number of Sequences: 164201
Number of extensions: 2623295
Number of successful extensions: 6937
Number of sequences better than 10.0: 185
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 6626
Number of HSP's gapped (non-prelim): 251
length of query: 433
length of database: 59,974,054
effective HSP length: 113
effective length of query: 320
effective length of database: 41,419,341
effective search space: 13254189120
effective search space used: 13254189120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Lotus: description of TM0087.18