BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0086.14
         (430 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PKS5_ARATH (O22932) SOS2-like protein kinase PKS5 (EC 2.7.1.37)       326  6e-89
SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinas...   231  4e-60
SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinas...   226  9e-59
SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinas...   225  1e-58
SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinas...   225  1e-58
KI10_ARATH (Q38997) SNF1-related protein kinase KIN10 (EC 2.7.1....   223  6e-58
MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC...   217  4e-56
MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC...   216  7e-56
KI11_HUMAN (Q8TDC3) Probable serine/threonine-protein kinase KIA...   213  1e-54
YNA3_CAEEL (P45894) Putative serine/threonine-protein kinase PAR...   211  2e-54
MRK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4...   208  2e-53
AAK2_HUMAN (P54646) 5'-AMP-activated protein kinase, catalytic a...   206  9e-53
AAK2_RAT (Q09137) 5'-AMP-activated protein kinase, catalytic alp...   206  1e-52
ST29_HUMAN (Q8IWQ3) Serine/threonine-protein kinase 29 (EC 2.7.1...   204  5e-52
SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.1.-)        202  1e-51
AAK1_HUMAN (Q13131) 5'-AMP-activated protein kinase, catalytic a...   201  4e-51
AAK1_RAT (P54645) 5'-AMP-activated protein kinase, catalytic alp...   199  9e-51
GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7...   197  3e-50
MRK2_MOUSE (Q05512) MAP/microtubule affinity-regulating kinase 2...   196  1e-49
ARK5_HUMAN (O60285) AMPK-related protein kinase 5 (EC 2.7.1.37)       196  1e-49

>PKS5_ARATH (O22932) SOS2-like protein kinase PKS5 (EC 2.7.1.37)
          Length = 435

 Score =  326 bits (836), Expect = 6e-89
 Identities = 179/347 (51%), Positives = 240/347 (68%), Gaps = 22/347 (6%)

Query: 19  ILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTV-DAAMEPRIVREIDAMRR 77
           + GKY++ +LLG G+FAKV+ AR    G  VAVKI++K K + + A+   I REI  MRR
Sbjct: 17  LFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRR 76

Query: 78  LHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRF 137
           L H PNI+++HEVMATK+KI   +EF  GGELF+ IS+ G+L E+ +RRYFQQL+SA+ +
Sbjct: 77  LSH-PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGY 135

Query: 138 CHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQ-NGLLHTACGTPAYTAPEILR 196
           CH  GV HRDLKP+NLL+D  GNLKVSDFGLSAL + ++ +GLLHT CGTPAY APEIL 
Sbjct: 136 CHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILS 195

Query: 197 LSGGYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVI 256
              GY+G+K D WSCG+VLFVL+AGYLPF+D N+  MY+KI + +Y+FP W++   +  +
Sbjct: 196 -KKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFV 254

Query: 257 RRLLDPNPETRMSVEDLYGNSWFK----KSLKV---EAESETESSTLNLDSGYGNRVRGL 309
            RLLD NPETR++++++  + WF     K +K    E E +   S+L         V+ L
Sbjct: 255 SRLLDINPETRITIDEILKDPWFVRGGFKQIKFHDDEIEDQKVESSL-------EAVKSL 307

Query: 310 GVNAFDLISMSSGLDLSGLFQ--DEGKRKEKRFTSGAKLEVVEEKVK 354
             NAFDLIS SSGLDLSGLF        + +RF S    E++ E+V+
Sbjct: 308 --NAFDLISYSSGLDLSGLFAGCSNSSGESERFLSEKSPEMLAEEVE 352


>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase
           (EC 2.7.1.-)
          Length = 619

 Score =  231 bits (588), Expect = 4e-60
 Identities = 120/283 (42%), Positives = 188/283 (66%), Gaps = 8/283 (2%)

Query: 2   EPPMRQPPPPRSSAATTILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVD 61
           +P    P  P  + A  I G+YQ+I+ LG GSF KV  A+ +  G  VA+KII++     
Sbjct: 32  QPAQPIPIDPNVNPANRI-GRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAK 90

Query: 62  AAMEPRIVREIDAMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPE 121
           + M+ R+ REI  +R L H P+I+++++V+ +K +I +V+EFA G ELF  I +RGK+PE
Sbjct: 91  SDMQGRVEREISYLRLLRH-PHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPE 148

Query: 122 NTARRYFQQLVSALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLH 181
           + ARR+FQQ+++A+ +CHR+ + HRDLKP+NLLLD   N+K++DFGLS +        L 
Sbjct: 149 DEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNI--MTDGNFLK 206

Query: 182 TACGTPAYTAPEILRLSGG-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRR 240
           T+CG+P Y APE+  +SG  Y G + D WS G++L+V+L G LPFDD  I A+++KIS  
Sbjct: 207 TSCGSPNYAAPEV--ISGKLYAGPEVDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNG 264

Query: 241 DYQFPEWITKPARFVIRRLLDPNPETRMSVEDLYGNSWFKKSL 283
            Y  P +++  A+ ++ R+L  NP  R+++ ++  + WFK+ +
Sbjct: 265 VYTLPNYLSPGAKHLLTRMLVVNPLNRITIHEIMEDEWFKQDM 307


>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase
           (EC 2.7.1.-)
          Length = 620

 Score =  226 bits (576), Expect = 9e-59
 Identities = 119/278 (42%), Positives = 187/278 (66%), Gaps = 9/278 (3%)

Query: 8   PPPPRSSAATTILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPR 67
           P  P ++ A  I G+YQ+++ LG GSF KV  A+ L  G  VA+KII++     + M+ R
Sbjct: 39  PIDPAANPANRI-GRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGR 97

Query: 68  IVREIDAMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRY 127
           + REI  +R L H P+I+++++V+ +K +I +V+EFA G ELF  I +RGK+PE+ ARR+
Sbjct: 98  VEREISYLRLLRH-PHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRF 155

Query: 128 FQQLVSALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTP 187
           FQQ+++A+ +CHR+ + HRDLKP+NLLLD   N+K++DFGLS +        L T+CG+P
Sbjct: 156 FQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNI--MTDGNFLKTSCGSP 213

Query: 188 AY-TAPEILRLSGG-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFP 245
            Y  APE+  +SG  Y G + D WS G++L+V+L G LPFDD  I A+++KIS   Y  P
Sbjct: 214 NYMPAPEV--ISGKLYAGPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLP 271

Query: 246 EWITKPARFVIRRLLDPNPETRMSVEDLYGNSWFKKSL 283
            +++  A+ ++ R+L  NP  R+++ ++  + WFK+ +
Sbjct: 272 NYLSAGAKHLLTRMLVVNPLNRITIHEIMEDDWFKQDM 309


>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase
           (EC 2.7.1.-)
          Length = 633

 Score =  225 bits (574), Expect = 1e-58
 Identities = 127/331 (38%), Positives = 200/331 (60%), Gaps = 18/331 (5%)

Query: 11  PRSSAATTI-LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIV 69
           P+SS A    +G YQ+++ LG GSF KV  A     G  VA+KII+K     + M+ RI 
Sbjct: 42  PKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIE 101

Query: 70  REIDAMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQ 129
           REI  +R L H P+I+++++V+ +K +I +V+E+A G ELF  I +R K+ E  ARR+FQ
Sbjct: 102 REISYLRLLRH-PHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQ 159

Query: 130 QLVSALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAY 189
           Q++SA+ +CHR+ + HRDLKP+NLLLD   N+K++DFGLS +        L T+CG+P Y
Sbjct: 160 QIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNI--MTDGNFLKTSCGSPNY 217

Query: 190 TAPEILRLSGG-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWI 248
            APE+  +SG  Y G + D WSCG++L+V+L   LPFDD +I  +++ IS   Y  P+++
Sbjct: 218 AAPEV--ISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFL 275

Query: 249 TKPARFVIRRLLDPNPETRMSVEDLYGNSWFK---------KSLKVEAESETESSTLNLD 299
           +  A  +I+R+L  NP  R+S+ ++  + WFK           LK   E E E++    D
Sbjct: 276 SPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENENNDSKKD 335

Query: 300 SGYGNRVRGLGVNAFDLISMSSGLDLSGLFQ 330
               +    +  N  +++S + G +   +++
Sbjct: 336 GSSPDNDE-IDDNLVNILSSTMGYEKDEIYE 365


>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase
           (EC 2.7.1.-)
          Length = 612

 Score =  225 bits (574), Expect = 1e-58
 Identities = 122/314 (38%), Positives = 192/314 (60%), Gaps = 9/314 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G YQ+++ LG GSF KV  A  +  G  VA+KII+K     + M+ RI REI  +R L 
Sbjct: 36  VGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 95

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
           H P+I+++++V+ +K +I +V+E+A G ELF  I +R K+ E  ARR+FQQ++SA+ +CH
Sbjct: 96  H-PHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCH 153

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           R+ + HRDLKP+NLLLD   N+K++DFGLS +        L T+CG+P Y APE+  +SG
Sbjct: 154 RHKIVHRDLKPENLLLDEHLNVKIADFGLSNI--MTDGNFLKTSCGSPNYAAPEV--ISG 209

Query: 200 G-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WSCG++L+V+L   LPFDD +I  +++ IS   Y  P++++  A  +I+R
Sbjct: 210 KLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKR 269

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLK--VEAESETESSTLNLDSGYGNRVRGLGVNAFDL 316
           +L  NP  R+S+ ++  + WFK  L   +  +   +    N  SG    V  +       
Sbjct: 270 MLIVNPLNRISIHEIMQDEWFKVDLAEYLVPQDLKQQEQFNKKSGNEENVEEIDDEMVVT 329

Query: 317 ISMSSGLDLSGLFQ 330
           +S + G D   +++
Sbjct: 330 LSKTMGYDKDEIYE 343


>KI10_ARATH (Q38997) SNF1-related protein kinase KIN10 (EC 2.7.1.-)
           (AKIN10)
          Length = 535

 Score =  223 bits (569), Expect = 6e-58
 Identities = 118/272 (43%), Positives = 179/272 (65%), Gaps = 8/272 (2%)

Query: 14  SAATTILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREID 73
           S   +IL  Y++ R LG GSF +V  A   + G  VA+KI+++ K  +  ME ++ REI 
Sbjct: 33  SGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIK 92

Query: 74  AMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVS 133
            +R L  HP+I+R++EV+ T T I+LV+E+   GELF  I  +G+L E+ AR +FQQ++S
Sbjct: 93  ILR-LFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIIS 151

Query: 134 ALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNG-LLHTACGTPAYTAP 192
            + +CHRN V HRDLKP+NLLLD+  N+K++DFGLS +   +++G  L T+CG+P Y AP
Sbjct: 152 GVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNI---MRDGHFLKTSCGSPNYAAP 208

Query: 193 EILRLSGG-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKP 251
           E+  +SG  Y G + D WSCG++L+ LL G LPFDD NI  +++KI    Y  P  ++  
Sbjct: 209 EV--ISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPG 266

Query: 252 ARFVIRRLLDPNPETRMSVEDLYGNSWFKKSL 283
           AR +I R+L  +P  R+++ ++  + WF+  L
Sbjct: 267 ARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHL 298


>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC
           2.7.1.37) (Protein kinase PK38) (mPK38)
          Length = 643

 Score =  217 bits (553), Expect = 4e-56
 Identities = 110/281 (39%), Positives = 179/281 (63%), Gaps = 4/281 (1%)

Query: 19  ILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRL 78
           +L  Y++   +G G FAKV  A  ++ G +VA+KI+DK+     +  PR+  EIDA++ L
Sbjct: 7   LLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNAL--GSDLPRVKTEIDALKSL 64

Query: 79  HHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFC 138
            H  +I +++ V+ TK KI +V+E+  GGELF  I  + +L E   R  F+Q++SA+ + 
Sbjct: 65  RHQ-HICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYV 123

Query: 139 HRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLS 198
           H  G AHRDLKP+NLL D    LK+ DFGL A P+  ++  L T CG+ AY APE+++  
Sbjct: 124 HSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQ-G 182

Query: 199 GGYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y GS+AD WS G++L+VL+ G+LPFDD N+ A+Y+KI R  Y+ P+W++  +  ++++
Sbjct: 183 KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQ 242

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLKVEAESETESSTLNLD 299
           +L  +P+ R+S+ +L  + W  +      E ++++   +LD
Sbjct: 243 MLQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSKTPLTHLD 283


>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC
           2.7.1.37) (hMELK) (Protein kinase PK38) (hPK38)
          Length = 651

 Score =  216 bits (551), Expect = 7e-56
 Identities = 111/281 (39%), Positives = 182/281 (64%), Gaps = 4/281 (1%)

Query: 19  ILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRL 78
           +L  Y++   +G G FAKV  A  ++ G +VA+KI+DK+ T+ + + PRI  EI+A++ L
Sbjct: 7   LLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKN-TLGSDL-PRIKTEIEALKNL 64

Query: 79  HHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFC 138
            H  +I +++ V+ T  KI +V+E+  GGELF  I  + +L E   R  F+Q+VSA+ + 
Sbjct: 65  RHQ-HICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYV 123

Query: 139 HRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLS 198
           H  G AHRDLKP+NLL D    LK+ DFGL A P+  ++  L T CG+ AY APE+++  
Sbjct: 124 HSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQ-G 182

Query: 199 GGYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y GS+AD WS G++L+VL+ G+LPFDD N+ A+Y+KI R  Y  P+W++  +  ++++
Sbjct: 183 KSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQ 242

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLKVEAESETESSTLNLD 299
           +L  +P+ R+S+++L  + W  +      E ++++  ++LD
Sbjct: 243 MLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLD 283


>KI11_HUMAN (Q8TDC3) Probable serine/threonine-protein kinase
           KIAA1811 (EC 2.7.1.37)
          Length = 794

 Score =  213 bits (541), Expect = 1e-54
 Identities = 101/260 (38%), Positives = 169/260 (64%), Gaps = 5/260 (1%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y++ + LG+G    V      I G  VA+KI+++ K  ++ +  ++ REI A+ +L 
Sbjct: 47  VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM-KVEREI-AILKLI 104

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP++L++H+V   K  ++LV+E  +GGELF  + ++G+L    AR++F+Q+VSAL FCH
Sbjct: 105 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 164

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
              + HRDLKP+NLLLD   N++++DFG+++L   + + LL T+CG+P Y  PE+++   
Sbjct: 165 SYSICHRDLKPENLLLDEKNNIRIADFGMASL--QVGDSLLETSCGSPHYACPEVIK-GE 221

Query: 200 GYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRRL 259
            YDG +AD WSCG++LF LL G LPFDD N+  +  K+ R  +  P +I    + ++R +
Sbjct: 222 KYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGM 281

Query: 260 LDPNPETRMSVEDLYGNSWF 279
           ++  PE R+S+E +  + W+
Sbjct: 282 IEVEPEKRLSLEQIQKHPWY 301


>YNA3_CAEEL (P45894) Putative serine/threonine-protein kinase PAR2.3
           (EC 2.7.1.37)
          Length = 622

 Score =  211 bits (538), Expect = 2e-54
 Identities = 112/283 (39%), Positives = 176/283 (61%), Gaps = 8/283 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G + +   +G+G+F  V +   +  G  VA+KI+++ +        +   EID +++L 
Sbjct: 21  IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLT 80

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
           H P+I R+  V++T + I LV+E  +GGELFS I+R+G LP   +RRYFQQ++S + +CH
Sbjct: 81  H-PHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCH 139

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNG-LLHTACGTPAYTAPEILRLS 198
            + + HRDLKP+NLLLDA  N+K++DFGLS    ++ +G LL TACG+P Y APE++  +
Sbjct: 140 NHMIVHRDLKPENLLLDANKNIKIADFGLS---NYMTDGDLLSTACGSPNYAAPELIS-N 195

Query: 199 GGYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WSCG++L+ +L G LPFDD N+  ++ KI    Y  P  + K A  +I  
Sbjct: 196 KLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLIST 255

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLK--VEAESETESSTLNLD 299
           +L  +P  R  V+ +  +SWF+  L   +  E E ESS +++D
Sbjct: 256 MLQVDPVKRADVKRIVNHSWFRIDLPYYLFPECENESSIVDID 298


>MRK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4
           (EC 2.7.1.37) (MAP/microtubule affinity-regulating
           kinase like 1)
          Length = 752

 Score =  208 bits (529), Expect = 2e-53
 Identities = 124/361 (34%), Positives = 205/361 (56%), Gaps = 29/361 (8%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y+++R +G+G+FAKV  AR ++ G  VA+KIIDK++   ++++ ++ RE+  M+ L+
Sbjct: 56  VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQ-KLFREVRIMKGLN 114

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
           H PNI+++ EV+ T+  ++LV+E+A+ GE+F  +   G++ E  AR  F+Q+VSA+ +CH
Sbjct: 115 H-PNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           +  + HRDLK +NLLLDA  N+K++DFG S   E      L T CG+P Y APE+ +   
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFS--NEFTLGSKLDTFCGSPPYAAPELFQ-GK 230

Query: 200 GYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRRL 259
            YDG + D WS G++L+ L++G LPFD  N+  +  ++ R  Y+ P +++     ++RR 
Sbjct: 231 KYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRF 290

Query: 260 LDPNPETRMSVEDLYGNSWFKKSLKVEAESETESSTLNLDSGYGNRVRGLGVNAFDLISM 319
           L  NP  R ++E +  + W    + +  E E        +  +G+  R         I +
Sbjct: 291 LVLNPAKRCTLEQIMKDKW----INIGYEGEELKPYTEPEEDFGDTKR---------IEV 337

Query: 320 SSGLDLSGLFQDEGKRKEKRFTSGAKLEVVEEKVKEIGGVLGFKVEVGKDSTAIGLVKGK 379
             G+   G  ++E K   +  TS    EV    +     +LG K E G D  A GL   +
Sbjct: 338 MVGM---GYTREEIK---ESLTSQKYNEVTATYL-----LLGRKTEEGGDRGAPGLALAR 386

Query: 380 V 380
           V
Sbjct: 387 V 387


>AAK2_HUMAN (P54646) 5'-AMP-activated protein kinase, catalytic
           alpha-2 chain (EC 2.7.1.-) (AMPK alpha-2 chain)
          Length = 552

 Score =  206 bits (524), Expect = 9e-53
 Identities = 105/265 (39%), Positives = 168/265 (62%), Gaps = 6/265 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y +   LG G+F KV      + G  VAVKI+++ K     +  +I REI  ++ L 
Sbjct: 13  IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LF 71

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP+I+++++V++T T   +V+E+ +GGELF  I + G++ E  ARR FQQ++SA+ +CH
Sbjct: 72  RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           R+ V HRDLKP+N+LLDA  N K++DFGLS +        L T+CG+P Y APE+  +SG
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS--DGEFLRTSCGSPNYAAPEV--ISG 187

Query: 200 G-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WSCG++L+ LL G LPFDD ++  +++KI    +  PE++ +    ++  
Sbjct: 188 RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMH 247

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSL 283
           +L  +P  R +++D+  + WFK+ L
Sbjct: 248 MLQVDPLKRATIKDIREHEWFKQDL 272


>AAK2_RAT (Q09137) 5'-AMP-activated protein kinase, catalytic
           alpha-2 chain (EC 2.7.1.-) (AMPK alpha-2 chain)
          Length = 552

 Score =  206 bits (523), Expect = 1e-52
 Identities = 105/265 (39%), Positives = 168/265 (62%), Gaps = 6/265 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y +   LG G+F KV      + G  VAVKI+++ K     +  +I REI  ++ L 
Sbjct: 13  IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LF 71

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP+I+++++V++T T   +V+E+ +GGELF  I + G++ E  ARR FQQ++SA+ +CH
Sbjct: 72  RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCH 131

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           R+ V HRDLKP+N+LLDA  N K++DFGLS +        L T+CG+P Y APE+  +SG
Sbjct: 132 RHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMS--DGEFLRTSCGSPNYAAPEV--ISG 187

Query: 200 G-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WSCG++L+ LL G LPFDD ++  +++KI    +  PE++ +    ++  
Sbjct: 188 RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMH 247

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSL 283
           +L  +P  R +++D+  + WFK+ L
Sbjct: 248 MLQVDPLKRATIKDIREHEWFKQDL 272


>ST29_HUMAN (Q8IWQ3) Serine/threonine-protein kinase 29 (EC
           2.7.1.37) (BRSK2) (HUSSY-12)
          Length = 736

 Score =  204 bits (518), Expect = 5e-52
 Identities = 97/260 (37%), Positives = 167/260 (63%), Gaps = 5/260 (1%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y++ + LG+G    V      +    VA+KI+++ K  ++ +  ++ REI A+ +L 
Sbjct: 16  VGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLM-KVEREI-AILKLI 73

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP++L++H+V   K  ++LV+E  +GGELF  + ++G+L    AR++F+Q++SAL FCH
Sbjct: 74  EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
            + + HRDLKP+NLLLD   N++++DFG+++L   + + LL T+CG+P Y  PE++R   
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIADFGMASL--QVGDSLLETSCGSPHYACPEVIR-GE 190

Query: 200 GYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRRL 259
            YDG KAD WSCG++LF LL G LPFDD N+  +  K+ R  +  P +I    + ++R +
Sbjct: 191 KYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGM 250

Query: 260 LDPNPETRMSVEDLYGNSWF 279
            + +   R+++E +  + W+
Sbjct: 251 SEVDAARRLTLEHIQKHIWY 270


>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.1.-)
          Length = 576

 Score =  202 bits (515), Expect = 1e-51
 Identities = 117/342 (34%), Positives = 193/342 (56%), Gaps = 12/342 (3%)

Query: 11  PRSSAATTILGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVR 70
           P  + +   +G Y +   LG GSF KV  A        VA+K I +     + M  R+ R
Sbjct: 22  PPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVER 81

Query: 71  EIDAMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQ 130
           EI  ++ L H P+I+++++V+ T T I +V+E+A GGELF  I  + ++ E+  RR+FQQ
Sbjct: 82  EISYLKLLRH-PHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQ 139

Query: 131 LVSALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYT 190
           ++ A+ +CHR+ + HRDLKP+NLLLD   N+K++DFGLS +        L T+CG+P Y 
Sbjct: 140 IICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI--MTDGNFLKTSCGSPNYA 197

Query: 191 APEILRLSGGYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITK 250
           APE++     Y G + D WSCG+VL+V+L G LPFDD  I  +++K++   Y  P++++ 
Sbjct: 198 APEVIN-GKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSP 256

Query: 251 PARFVIRRLLDPNPETRMSVEDLYGNSWFKKSLKVEAESETESSTLNLDSGYGNRVRGLG 310
            A+ +IRR++  +P  R++++++  + WF  +L        E      DS     V  LG
Sbjct: 257 GAQSLIRRMIVADPMQRITIQEIRRDPWFNVNLPDYLRPMEEVQGSYADS---RIVSKLG 313

Query: 311 VNAFDLISMSSGLDLSGLFQDEGKRKEKRFTSGAKLEVVEEK 352
               + +  S    +  L  DE    ++ +    + +V++EK
Sbjct: 314 ----EAMGFSEDYIVEALRSDENNEVKEAYNLLHENQVIQEK 351


>AAK1_HUMAN (Q13131) 5'-AMP-activated protein kinase, catalytic
           alpha-1 chain (EC 2.7.1.-) (AMPK alpha-1 chain)
          Length = 550

 Score =  201 bits (510), Expect = 4e-51
 Identities = 107/280 (38%), Positives = 175/280 (62%), Gaps = 8/280 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y +   LG G+F KV   +  + G  VAVKI+++ K     +  +I REI  ++ L 
Sbjct: 15  IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LF 73

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP+I+++++V++T + I +V+E+ +GGELF  I + G+L E  +RR FQQ++S + +CH
Sbjct: 74  RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 133

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           R+ V HRDLKP+N+LLDA  N K++DFGLS +        L T+CG+P Y APE+  +SG
Sbjct: 134 RHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS--DGEFLRTSCGSPNYAAPEV--ISG 189

Query: 200 G-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WS G++L+ LL G LPFDD ++  +++KI    +  P+++      +++ 
Sbjct: 190 RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKH 249

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLK--VEAESETESSTL 296
           +L  +P  R S++D+  + WFK+ L   +  E  + SST+
Sbjct: 250 MLQVDPMKRASIKDIREHEWFKQDLPKYLFPEDPSYSSTM 289


>AAK1_RAT (P54645) 5'-AMP-activated protein kinase, catalytic
           alpha-1 chain (EC 2.7.1.-) (AMPK alpha-1 chain)
          Length = 548

 Score =  199 bits (507), Expect = 9e-51
 Identities = 106/280 (37%), Positives = 175/280 (61%), Gaps = 8/280 (2%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y +   LG G+F KV   +  + G  VAVKI+++ K     +  +I REI  ++ L 
Sbjct: 13  IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LF 71

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
            HP+I+++++V++T + I +V+E+ +GGELF  I + G+L E  +RR FQQ++S + +CH
Sbjct: 72  RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 131

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           R+ V HRDLKP+N+LLDA  N K++DFGLS +        L T+CG+P Y APE+  +SG
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS--DGEFLRTSCGSPNYAAPEV--ISG 187

Query: 200 G-YDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRR 258
             Y G + D WS G++L+ LL G LPFDD ++  +++KI    +  P+++      +++ 
Sbjct: 188 RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKH 247

Query: 259 LLDPNPETRMSVEDLYGNSWFKKSLK--VEAESETESSTL 296
           +L  +P  R +++D+  + WFK+ L   +  E  + SST+
Sbjct: 248 MLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTM 287


>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC
           2.7.1.37)
          Length = 1142

 Score =  197 bits (502), Expect = 3e-50
 Identities = 113/281 (40%), Positives = 172/281 (60%), Gaps = 24/281 (8%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKS--------------KTVDAAME 65
           +G +++   LG GS  KV  AR+   G   AVK+I K+               T   A+ 
Sbjct: 16  IGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALP 75

Query: 66  PRIVREIDAMRRLHHHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTAR 125
             I REI  M+ L+H PN+LR+++V  T T ++LV+E+A  GELF+ +  RG LPE+ A 
Sbjct: 76  YGIEREIIIMKLLNH-PNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAI 134

Query: 126 RYFQQLVSALRFCHRNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACG 185
           R+F+Q++  + +CH  G+ HRDLKP+NLLLD   N+K++DFG++AL    +  LL T+CG
Sbjct: 135 RFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL--ETEGKLLETSCG 192

Query: 186 TPAYTAPEILRLSG-GYDGSKADAWSCGLVLFVLLAGYLPFD--DSNIAAMYRKISRRDY 242
           +P Y APEI  +SG  Y G  +D WSCG++LF LL G LPFD  D NI  +  K+ + ++
Sbjct: 193 SPHYAAPEI--VSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEF 250

Query: 243 QFP--EWITKPARFVIRRLLDPNPETRMSVEDLYGNSWFKK 281
           + P  + I++ A+ +IR++L  +PE R+   D+  +   +K
Sbjct: 251 EMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291


>MRK2_MOUSE (Q05512) MAP/microtubule affinity-regulating kinase 2
           (EC 2.7.1.37) (Serine/threonine-protein kinase Emk)
          Length = 774

 Score =  196 bits (498), Expect = 1e-49
 Identities = 97/259 (37%), Positives = 168/259 (64%), Gaps = 5/259 (1%)

Query: 20  LGKYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLH 79
           +G Y++++ +G+G+FAKV  AR ++ G  VAVKIIDK++   ++++ ++ RE+  M+ L+
Sbjct: 50  IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLN 108

Query: 80  HHPNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCH 139
           H PNI+++ EV+ T+  ++LV+E+A+GGE+F  +   G++ E  AR  F+Q+V  +++CH
Sbjct: 109 H-PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCH 167

Query: 140 RNGVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSG 199
           +  + HRDLK +NLLLDA  N+K++DFG S   E      L T CG+P Y APE+ +   
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFS--NEFTFGNKLDTFCGSPPYAAPELFQ-GK 224

Query: 200 GYDGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKPARFVIRRL 259
             DG + D WS G++L+ L++G LPFD  N+  +  ++ R  Y+ P +++     ++++ 
Sbjct: 225 KIDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 284

Query: 260 LDPNPETRMSVEDLYGNSW 278
           L  NP  R ++E +  + W
Sbjct: 285 LILNPSKRGTLEQIMKDRW 303


>ARK5_HUMAN (O60285) AMPK-related protein kinase 5 (EC 2.7.1.37)
          Length = 661

 Score =  196 bits (497), Expect = 1e-49
 Identities = 115/295 (38%), Positives = 181/295 (60%), Gaps = 14/295 (4%)

Query: 22  KYQVIRLLGRGSFAKVYQARSLIDGTIVAVKIIDKSKTVDAAMEPRIVREIDAMRRLHHH 81
           +Y++   LG+G++ KV +A     G +VA+K I K K  D      I REI+ M  L+H 
Sbjct: 54  RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNH- 112

Query: 82  PNILRIHEVMATKTKIHLVVEFAAGGELFSAISRRGKLPENTARRYFQQLVSALRFCHRN 141
           P+I+ I+EV   K KI +++E+A+ GEL+  IS R +L E   R +F+Q+VSA+ +CH+N
Sbjct: 113 PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKN 172

Query: 142 GVAHRDLKPQNLLLDAAGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEILRLSGGY 201
           GV HRDLK +N+LLD   N+K++DFGLS L  + ++  L T CG+P Y +PEI+     Y
Sbjct: 173 GVVHRDLKLENILLDDNCNIKIADFGLSNL--YQKDKFLQTFCGSPLYASPEIVN-GRPY 229

Query: 202 DGSKADAWSCGLVLFVLLAGYLPFDDSNIAAMYRKISRRDYQFPEWITKP--ARFVIRRL 259
            G + D+W+ G++L+ L+ G +PFD  +   + R+IS  +Y+ P   T+P  AR +IR +
Sbjct: 230 RGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREP---TQPSDARGLIRWM 286

Query: 260 LDPNPETRMSVEDLYGNSW----FKKSL-KVEAESETESSTLNLDSGYGNRVRGL 309
           L  NP+ R ++ED+  + W    +K S+   +A  ++ES  L     + +R  GL
Sbjct: 287 LMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGL 341


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.138    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,895,767
Number of Sequences: 164201
Number of extensions: 2159893
Number of successful extensions: 10381
Number of sequences better than 10.0: 1684
Number of HSP's better than 10.0 without gapping: 1479
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 5926
Number of HSP's gapped (non-prelim): 1955
length of query: 430
length of database: 59,974,054
effective HSP length: 113
effective length of query: 317
effective length of database: 41,419,341
effective search space: 13129931097
effective search space used: 13129931097
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)