BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0082b.8
         (726 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)      91  1e-17
BAR1_MOUSE (O70445) BRCA1-associated RING domain protein 1 (BARD-1)    87  2e-16
BAR1_HUMAN (Q99728) BRCA1-associated RING domain protein 1 (BARD-1)    86  3e-16
BRC1_MOUSE (P48754) Breast cancer type 1 susceptibility protein ...    78  7e-14
BRC1_PONPY (Q6J6J0) Breast cancer type 1 susceptibility protein ...    78  9e-14
BRC1_PANTR (Q9GKK8) Breast cancer type 1 susceptibility protein ...    78  9e-14
BRC1_HUMAN (P38398) Breast cancer type 1 susceptibility protein        78  9e-14
BRC1_BOVIN (Q864U1) Breast cancer type 1 susceptibility protein ...    77  2e-13
BRC1_GORGO (Q6J6I8) Breast cancer type 1 susceptibility protein ...    76  3e-13
BRC1_RAT (O54952) Breast cancer type 1 susceptibility protein ho...    75  6e-13
BRC1_MACMU (Q6J6I9) Breast cancer type 1 susceptibility protein ...    74  2e-12
BRC1_CANFA (Q95153) Breast cancer type 1 susceptibility protein ...    72  5e-12
TRX_DROVI (Q24742) Trithorax protein                                   72  7e-12
TRX_DROME (P20659) Trithorax protein                                   72  7e-12
TF20_MOUSE (Q9EPQ8) Transcription factor 20 (Stromelysin 1 PDGF-...    71  9e-12
TF20_HUMAN (Q9UGU0) Transcription factor 20 (Stromelysin 1 PDGF-...    71  9e-12
PHF6_MOUSE (Q9D4J7) PHD finger protein 6                               65  5e-10
PHF6_HUMAN (Q8IWS0) PHD finger protein 6 (PHD-like zinc finger p...    64  1e-09
RAI1_HUMAN (Q7Z5J4) Retinoic acid induced protein 1                    62  4e-09
RAI1_MOUSE (Q61818) Retinoic acid induced protein 1                    60  2e-08

>BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)
          Length = 768

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 61/213 (28%), Positives = 97/213 (44%), Gaps = 16/213 (7%)

Query: 512 VSGRGEVLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILNGRWVLKI 571
           +S + + LL    + + A     + + VTHVI   +       TLK ++ ILNG WVLK 
Sbjct: 568 LSSQQQKLLSKLETVLKAKKCAEFDNTVTHVIVPDEE---AQSTLKCMLGILNGCWVLKF 624

Query: 572 DWIKACMKVMSLVEEEPYEISLDNQGCNGGPKAGRLSALANEPKLFSGLKFYFSGDYVSS 631
           DW+KAC+      +EE YE+        GGP+  RL+     PKLF G  F+  G++   
Sbjct: 625 DWVKACLDSQEREQEEKYEVP-------GGPQRSRLNREQLLPKLFDGCYFFLGGNFKHH 677

Query: 632 YKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNL-LIVYNLDPPQGSKLGDEVSTLWQ 690
            KEDL  L+   GG +L+ K K ++     +VT  +  + Y+  P    +   +      
Sbjct: 678 PKEDLLKLIAAAGGRILSRKPKPDS-----DVTQTINTVAYHAKPDSDQRFCTQYIVYED 732

Query: 691 RLNEAEDLAANTGSQVIGHTWILESIAACKLQP 723
             N   +        +   TW++  + A +L P
Sbjct: 733 LFNCHPERVRQGKVWMAPSTWLISCVMAFELLP 765



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 14/136 (10%)

Query: 28  LKCPLCLSLFEKPVLLP-CDHLFCDSCLVDSSLSGSECAVCKTKYAQTDIRNVPFVENMV 86
           L+C  C ++  +PV L  C+H+FC  C+  S   GS C VC T     D++    +++M+
Sbjct: 42  LRCSRCANILREPVCLGGCEHIFCSGCI--SDCVGSGCPVCHTPAWILDLKINRQLDSMI 99

Query: 87  AIYRSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQS--SPNSNGFGV 144
            +Y  L      ++L      DS+      T R S + + ++  N  +   SP S     
Sbjct: 100 QLYSKLQ-----NLLHDNKGSDSK----DDTSRASLFGDAERKKNSVKMWFSPRSKKIRC 150

Query: 145 GENRKSMITMHVKPEE 160
             N+ S+ T   K ++
Sbjct: 151 VVNKVSVQTQPQKAKD 166


>BAR1_MOUSE (O70445) BRCA1-associated RING domain protein 1 (BARD-1)
          Length = 765

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 64/238 (26%), Positives = 103/238 (42%), Gaps = 34/238 (14%)

Query: 487 VVFCGSALSDEEKGSIENLRVMAVVVSGRGEVLLINFASKVGATVTKFWTSDVTHVIAAT 546
           +VF GS LS +++  +  L  +                  + A     + S VTHVI   
Sbjct: 558 LVFIGSGLSSQQQKMLSKLETV------------------LKAKKCMEFDSTVTHVIVPD 599

Query: 547 DANGACSRTLKVLMAILNGRWVLKIDWIKACMKVMSLVEEEPYEISLDNQGCNGGPKAGR 606
           +       TLK ++ IL+G W+LK DW+KAC+      +EE YE+        GGP+  R
Sbjct: 600 EE---AQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVP-------GGPQRSR 649

Query: 607 LSALANEPKLFSGLKFYFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSN 666
           L+     PKLF G  F+  G++    ++DL  L+   GG VL+ K K ++     +VT  
Sbjct: 650 LNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDS-----DVTQT 704

Query: 667 L-LIVYNLDPPQGSKLGDEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQP 723
           +  + Y+  P    +   +        N   +        +   TW++  I A +L P
Sbjct: 705 INTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLP 762



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 39/132 (29%), Positives = 57/132 (42%), Gaps = 33/132 (25%)

Query: 28  LKCPLCLSLFEKPVLLP-CDHLFCDSCLVDSSLSGSECAVCKTKYAQTDIRNVPFVENMV 86
           L+C  C ++ ++PV L  C+H+FC  C+  S   GS C VC T     D++         
Sbjct: 42  LRCSRCANILKEPVCLGGCEHIFCSGCI--SDCVGSGCPVCYTPAWILDLK--------- 90

Query: 87  AIYRSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQSSPNSNGFGVGE 146
            I R LD     SM+Q  S             ++  + N    DN S++S     FG  E
Sbjct: 91  -INRQLD-----SMIQLSSK-----------LQNLLHDNKDSKDNTSRASL----FGDAE 129

Query: 147 NRKSMITMHVKP 158
            +K+ I M   P
Sbjct: 130 RKKNSIKMWFSP 141


>BAR1_HUMAN (Q99728) BRCA1-associated RING domain protein 1 (BARD-1)
          Length = 777

 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 59/167 (35%), Positives = 83/167 (49%), Gaps = 28/167 (16%)

Query: 487 VVFCGSALSDEEKGSIENLRVMAVVVSGRGEVLLINFASKVGATVTKFWTSDVTHVIAAT 546
           +V  GS LS E++  +  L   AV++  +                T+F  S VTHV+   
Sbjct: 570 LVLIGSGLSSEQQKMLSEL---AVILKAK--------------KYTEF-DSTVTHVVVPG 611

Query: 547 DANGACSRTLKVLMAILNGRWVLKIDWIKACMKVMSLVEEEPYEISLDNQGCNGGPKAGR 606
           DA      TLK ++ ILNG W+LK +W+KAC++     +EE YEI         GP+  R
Sbjct: 612 DA---VQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIP-------EGPRRSR 661

Query: 607 LSALANEPKLFSGLKFYFSGDYVSSYKEDLEDLVEVGGGAVLTSKDK 653
           L+     PKLF G  FY  G +    K++L  LV  GGG +L+ K K
Sbjct: 662 LNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPK 708



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 31/132 (23%)

Query: 28  LKCPLCLSLFEKPVLLP-CDHLFCDSCLVDSSLSGSECAVCKTKYAQTDIRNVPFVENMV 86
           L+C  C ++  +PV L  C+H+FC +C+  S   G+ C VC T     D++         
Sbjct: 48  LRCSRCTNILREPVCLGGCEHIFCSNCV--SDCIGTGCPVCYTPAWIQDLK--------- 96

Query: 87  AIYRSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQSSPNSNGFGVGE 146
            I R LD+                ++Q C   R+  + N  +  +  +  P  + F    
Sbjct: 97  -INRQLDS----------------MIQLCSKLRNLLHDN--ELSDLKEDKPRKSLFNDAG 137

Query: 147 NRKSMITMHVKP 158
           N+K+ I M   P
Sbjct: 138 NKKNSIKMWFSP 149


>BRC1_MOUSE (P48754) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1812

 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 62/240 (25%), Positives = 111/240 (45%), Gaps = 28/240 (11%)

Query: 485  KKVVFCGSALSDEEKGSIENL-RVMAVVVSGRG--EVLLIN-FASKVGATVTKFWTSDVT 540
            K VV   S +  E   S E   R +++VVSG    EV+ +  FA K   T+T   T + T
Sbjct: 1569 KAVVGIVSKIKPELTSSEERADRDISMVVSGLTPKEVMTVQKFAEKYRLTLTDAITEETT 1628

Query: 541  HVIAATDANGACSRTLKVLMAILNGRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGC 598
            HVI  TDA   C RTLK  + I  G+W++   W+   ++   L+    +E++ D      
Sbjct: 1629 HVIIKTDAEFVCERTLKYFLGIAGGKWIVSYSWVVRSIQERRLLNVHEFEVTGDVVTGRN 1688

Query: 599  NGGPKAGRLSALANEPKLFSGLKFYFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKR 658
            + GP+  R S      KLF GL+ Y    + +  K+DLE ++++ G +V+     L    
Sbjct: 1689 HQGPRRSRES----REKLFKGLQVYCCDPFTNMPKDDLERMLQLCGASVVKELPSL---- 1740

Query: 659  HEFEVTSNLLIVYNLDPPQGSKLGDEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAA 718
               +  ++L+++                + W   +   D+     ++++   W+L+S+++
Sbjct: 1741 -THDTGAHLVVIVQ-------------PSAWTEDSNCPDIGQLCKARLVMWDWVLDSLSS 1786



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 27/111 (24%), Positives = 50/111 (44%), Gaps = 13/111 (11%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKTKYAQTDIRNVPFVEN 84
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK +  +  ++       
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNEITKRSLQGSTRFSQ 81

Query: 85  MVAIYRSLDASF----------CASMLQQRSNDDSRVLQQCQTFRDSSYSN 125
           +      + A+F            S  ++R+N   R+ ++    +   Y N
Sbjct: 82  LAEELLRIMAAFELDTGMQLTNGFSFSKKRNNSCERLNEEASIIQSVGYRN 132


>BRC1_PONPY (Q6J6J0) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1863

 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 58/220 (26%), Positives = 99/220 (44%), Gaps = 26/220 (11%)

Query: 508  MAVVVSGRGE---VLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILN 564
            M++VVSG      +L+  FA K   T+T   T + THV+  TDA   C RTLK  + I  
Sbjct: 1650 MSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAG 1709

Query: 565  GRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKF 622
            G+WV+   W+   +K   ++ E  +E+  D  N   + GPK  R S    + K+F GL+ 
Sbjct: 1710 GKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARES---QDRKIFRGLEI 1766

Query: 623  YFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSKLG 682
               G + +   + LE +V++ G +V+        +   F + + +  +  + P       
Sbjct: 1767 CCYGPFTNMPTDQLEWIVQLCGASVV-------KELSSFTLGTGVHPIVVVQP------- 1812

Query: 683  DEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQ 722
                  W   N    +     + V+   W+L+S+A  + Q
Sbjct: 1813 ----DAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ 1848



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 32/125 (25%), Positives = 54/125 (42%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIY------RSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I         L  +   +  ++ +N    +  +    +   Y N  +A    Q
Sbjct: 82  LVEELLKIICAFQLDTGLQYANSYNFAKKENNSPEHLKDEVSIIQSMGYRN--RAKRLLQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_PANTR (Q9GKK8) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1863

 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 58/220 (26%), Positives = 99/220 (44%), Gaps = 26/220 (11%)

Query: 508  MAVVVSGRGE---VLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILN 564
            M++VVSG      +L+  FA K   T+T   T + THV+  TDA   C RTLK  + I  
Sbjct: 1650 MSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAG 1709

Query: 565  GRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKF 622
            G+WV+   W+   +K   ++ E  +E+  D  N   + GPK  R S    + K+F GL+ 
Sbjct: 1710 GKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARES---QDRKIFRGLEI 1766

Query: 623  YFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSKLG 682
               G + +   + LE +V++ G +V+        +   F + + +  +  + P       
Sbjct: 1767 CCYGPFTNMPTDQLEWMVQLCGASVV-------KELSSFTLGTGVHPIVVVQP------- 1812

Query: 683  DEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQ 722
                  W   N    +     + V+   W+L+S+A  + Q
Sbjct: 1813 ----DAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ 1848



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 32/125 (25%), Positives = 55/125 (43%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIY------RSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I         L+ +   +  ++ +N    +  +    +   Y N  +A    Q
Sbjct: 82  LVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRN--RAKRLLQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_HUMAN (P38398) Breast cancer type 1 susceptibility protein
          Length = 1863

 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 58/220 (26%), Positives = 99/220 (44%), Gaps = 26/220 (11%)

Query: 508  MAVVVSGRGE---VLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILN 564
            M++VVSG      +L+  FA K   T+T   T + THV+  TDA   C RTLK  + I  
Sbjct: 1650 MSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAG 1709

Query: 565  GRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKF 622
            G+WV+   W+   +K   ++ E  +E+  D  N   + GPK  R S    + K+F GL+ 
Sbjct: 1710 GKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARES---QDRKIFRGLEI 1766

Query: 623  YFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSKLG 682
               G + +   + LE +V++ G +V+        +   F + + +  +  + P       
Sbjct: 1767 CCYGPFTNMPTDQLEWMVQLCGASVV-------KELSSFTLGTGVHPIVVVQP------- 1812

Query: 683  DEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQ 722
                  W   N    +     + V+   W+L+S+A  + Q
Sbjct: 1813 ----DAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ 1848



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 32/125 (25%), Positives = 55/125 (43%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIY------RSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I         L+ +   +  ++ +N    +  +    +   Y N  +A    Q
Sbjct: 82  LVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRN--RAKRLLQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_BOVIN (Q864U1) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1849

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 55/198 (27%), Positives = 100/198 (49%), Gaps = 10/198 (5%)

Query: 453  SRPKKQATQEHPASAHLSSQLSNPLGAFHDDGKKVVFCGSALSDEEKGSIENLRVMAVVV 512
            S+ + + + ++PA+AH+++     L       +K       +S  E+ S + L ++A  +
Sbjct: 1596 SQFRVEESTKNPAAAHIANTTRCNLREESMSKEKP----EVISSTER-SKKRLSMVASGL 1650

Query: 513  SGRGEVLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILNGRWVLKID 572
            + +  +L+  FA K   T+T   T + THVI  TD    C RTLK  + I  G+WV+   
Sbjct: 1651 TPKELMLVQKFARKHHVTLTNLITEETTHVIMKTDPEFVCERTLKYFLGIAGGKWVVSYF 1710

Query: 573  WIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKFYFSGDYVS 630
            W+   +K   +++E  +E+  D  N   + GPK  R S    + K+F GL+    G + +
Sbjct: 1711 WVTQSIKEGKMLDEHDFEVRGDVVNGRNHQGPKRARES---RDKKIFKGLEICCYGPFTN 1767

Query: 631  SYKEDLEDLVEVGGGAVL 648
               + LE +V++ G +V+
Sbjct: 1768 MPTDQLEWMVQLCGASVV 1785



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIYRSLD----ASFCASMLQQRSNDDS--RVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I  + +      F  S    R  D+S   + ++    +   Y N  +A    Q
Sbjct: 82  LVEELLKIIHAFELDTGLQFANSYNFSRKEDNSPEHLKEEVSIIQSMGYRN--RAKRLWQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_GORGO (Q6J6I8) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1863

 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 58/220 (26%), Positives = 98/220 (44%), Gaps = 26/220 (11%)

Query: 508  MAVVVSGRGE---VLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILN 564
            M++VVSG      +L+  FA K   T+T   T + THV+  TDA   C RTLK  + I  
Sbjct: 1650 MSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAG 1709

Query: 565  GRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKF 622
            G+WV+   W+   +K   ++ E  +E+  D  N   + GPK  R S    + K+F GL  
Sbjct: 1710 GKWVVSYFWVTQSIKEGKMLNEHDFEVRGDVVNGRNHQGPKRARES---QDRKIFRGLDI 1766

Query: 623  YFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSKLG 682
               G + +   + LE +V++ G +V+        +   F + + +  +  + P       
Sbjct: 1767 CCYGPFTNMPTDQLEWMVQLCGASVV-------KELSSFTLGTGVHPIVVVQP------- 1812

Query: 683  DEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQ 722
                  W   N    +     + V+   W+L+S+A  + Q
Sbjct: 1813 ----DAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ 1848



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIY------RSLDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I         L+ +   +  ++ +N    +  +    + + Y +  +A    Q
Sbjct: 82  LVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSTGYRS--RAKRLLQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_RAT (O54952) Breast cancer type 1 susceptibility protein homolog
          Length = 1817

 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 54/217 (24%), Positives = 101/217 (45%), Gaps = 27/217 (12%)

Query: 506  RVMAVVVSGRG--EVLLIN-FASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAI 562
            R +++VVSG    EV+++  FA K    +T   T + THVI  TDA   C RTLK  + I
Sbjct: 1594 RDISMVVSGLTPKEVMIVQKFAEKYRLALTDVITEETTHVIIKTDAEFVCERTLKYFLGI 1653

Query: 563  LNGRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGL 620
              G+W++   W+   ++   L+    +E+  D      + GP+  R S    + KLF GL
Sbjct: 1654 AGGKWIVSYSWVIKSIQERKLLSVHEFEVKGDVVTGSNHQGPRRSRES----QEKLFEGL 1709

Query: 621  KFYFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSK 680
            + Y    + +  K++LE ++++ G +V+     L       +  ++ +++          
Sbjct: 1710 QIYCCEPFTNMPKDELERMLQLCGASVVKELPLLTR-----DTGAHPIVLVQ-------- 1756

Query: 681  LGDEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIA 717
                  + W   N+  D+      +++   W+L+SI+
Sbjct: 1757 -----PSAWTEDNDCPDIGQLCKGRLVMWDWVLDSIS 1788



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 14/123 (11%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKTKYA----QTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK +      Q   R   
Sbjct: 22  LECPICLELIKEPVSTQCDHIFCKFCMLKLLNQKKGPSQCPLCKNEITKRSLQGSARFSQ 81

Query: 81  FVENMVAIYRSLDASF---CAS--MLQQRSNDDSRVL-QQCQTFRDSSYSN-IKKADNFS 133
            VE ++ I  + +      CA+     ++ N  S +L +     +   Y N +KK     
Sbjct: 82  LVEELLKIIDAFELDTGMQCANGFSFSKKKNSSSELLNEDASIIQSVGYRNRVKKLQQIE 141

Query: 134 QSS 136
             S
Sbjct: 142 SGS 144


>BRC1_MACMU (Q6J6I9) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1863

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 26/220 (11%)

Query: 508  MAVVVSGRGE---VLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKVLMAILN 564
            M++VVSG      +L+  FA +    +T   + + THV+  TDA   C RTLK  + I  
Sbjct: 1650 MSLVVSGLTPEEFMLVYKFARRYHIALTNLISEETTHVVMKTDAEFVCERTLKYFLGIAG 1709

Query: 565  GRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLSALANEPKLFSGLKF 622
            G+WV+   W+   +K   ++ E  +E+  D  N   + GPK  R S    + K+F GL+ 
Sbjct: 1710 GKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESP---DRKIFRGLEI 1766

Query: 623  YFSGDYVSSYKEDLEDLVEVGGGAVLTSKDKLEAKRHEFEVTSNLLIVYNLDPPQGSKLG 682
               G + +   + LE +V++ G +V+      E          + ++V   D        
Sbjct: 1767 CCYGPFTNMPTDQLEWMVQLCGASVVK-----ELSSFTLGTGFHPIVVVQPD-------- 1813

Query: 683  DEVSTLWQRLNEAEDLAANTGSQVIGHTWILESIAACKLQ 722
                  W   N    +     + V+   W+L+S+A  + Q
Sbjct: 1814 -----AWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ 1848



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 31/125 (24%), Positives = 55/125 (43%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCRFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIYRS------LDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I  +      L  +   +  ++ ++    +  +    +   Y N  +A    Q
Sbjct: 82  LVEELLKIIHAFQLDTGLQFANSYNFAKKENHSPEHLKDEVSIIQSMGYRN--RAKRLLQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>BRC1_CANFA (Q95153) Breast cancer type 1 susceptibility protein
            homolog
          Length = 1878

 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 4/154 (2%)

Query: 499  KGSIENLRVMAVVVSGRGEVLLINFASKVGATVTKFWTSDVTHVIAATDANGACSRTLKV 558
            +G  + + ++A  ++ +  +L+  FA K   ++T   + + THVI  TDA   C RTLK 
Sbjct: 1647 RGVNKRISMVASGLTPKEFMLVHKFARKHHISLTNLISEETTHVIMKTDAEFVCERTLKY 1706

Query: 559  LMAILNGRWVLKIDWIKACMKVMSLVEEEPYEISLD--NQGCNGGPKAGRLS--ALANEP 614
             + I  G+WV+   W+   +K   +++E  +E+  D  N   + GPK  R S    + + 
Sbjct: 1707 FLGIAGGKWVVSYFWVTQSIKERKILDEHDFEVRGDVVNGRNHQGPKRARESQDRESQDR 1766

Query: 615  KLFSGLKFYFSGDYVSSYKEDLEDLVEVGGGAVL 648
            K+F GL+    G + +   + LE +V + G +V+
Sbjct: 1767 KIFRGLEICCYGPFTNMPTDQLEWMVHLCGASVV 1800



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 28  LKCPLCLSLFEKPVLLPCDHLFCDSC---LVDSSLSGSECAVCKT----KYAQTDIRNVP 80
           L+CP+CL L ++PV   CDH+FC  C   L++     S+C +CK     +  Q   R   
Sbjct: 22  LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQCPLCKNDITKRSLQESTRFSQ 81

Query: 81  FVENMVAIYRS------LDASFCASMLQQRSNDDSRVLQQCQTFRDSSYSNIKKADNFSQ 134
            VE ++ I  +      L  +   +  ++ +N    + ++    +   Y N  +A    Q
Sbjct: 82  LVEELLKIIHAFELDTGLQFADSYNFSKKENNSPEHLKEEVSIIQSMGYRN--RAKRLRQ 139

Query: 135 SSPNS 139
           S P +
Sbjct: 140 SEPEN 144


>TRX_DROVI (Q24742) Trithorax protein
          Length = 3828

 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/125 (33%), Positives = 64/125 (50%), Gaps = 20/125 (16%)

Query: 324  TSICSFCQSSETSEATGPMLHYANGKSVIGDAAMQPNVIH---VHRCCVDWAPQVYF-VD 379
            T +C FC+ S              G+ + G+ A      H   VH  C  W+ +V+  +D
Sbjct: 1708 TRVCLFCRKS--------------GEGLSGEEARLLYCGHDCWVHINCAMWSAEVFEEID 1753

Query: 380  ETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAMDVSTCRWDQEKYLLL 439
             + +N+ + VARG  +KC+ CG +GA +GC VKSC   YH PCA  +  C +  +K  + 
Sbjct: 1754 GSLQNVHSAVARGRMIKCTVCGNRGATVGCNVKSCGEHYHYPCARTID-CAFLTDK-SMY 1811

Query: 440  CPVHS 444
            CP H+
Sbjct: 1812 CPAHA 1816


>TRX_DROME (P20659) Trithorax protein
          Length = 3726

 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 20/131 (15%)

Query: 318  IDLNPSTSICSFCQSSETSEATGPMLHYANGKSVIGDAAMQPNVIH---VHRCCVDWAPQ 374
            I +   T +C FC+ S              G+ + G+ A      H   VH  C  W+ +
Sbjct: 1728 IKMRLDTRMCLFCRKS--------------GEGLSGEEARLLYCGHDCWVHTNCAMWSAE 1773

Query: 375  VYF-VDETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAMDVSTCRWDQ 433
            V+  +D + +N+ + VARG  +KC+ CG +GA +GC V+SC   YH PCA  +  C +  
Sbjct: 1774 VFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSID-CAFLT 1832

Query: 434  EKYLLLCPVHS 444
            +K  + CP H+
Sbjct: 1833 DK-SMYCPAHA 1842


>TF20_MOUSE (Q9EPQ8) Transcription factor 20 (Stromelysin 1
            PDGF-responsive element-binding protein) (SPRE-binding
            protein) (Nuclear factor SPBP)
          Length = 1983

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 78/317 (24%), Positives = 121/317 (37%), Gaps = 24/317 (7%)

Query: 154  MHVKPEELEMSSGGRAGFRNDVKPYPMQRSRVEIGDYVEMDVNQVTQAAVYSPPFCDTKG 213
            ++ + EE       R G R+   P     S+V       +    VT+++V     C   G
Sbjct: 1678 INAEEEEQTKLVRSRKGQRSLTPPPSSTESKVLPASSFMLQGPVVTESSVMGHLVCCLCG 1737

Query: 214  SDNDCSEL-DSDHPFNPE-----ILENSSLKRASTGKGNLKERKSQFRSESSASETDKPT 267
                   + D   PF P+     + +N   KR+S  +  +K R    +S S+ S+TD   
Sbjct: 1738 KWASYRNMGDLFGPFYPQDYAATLPKNPPPKRSSEMQSKVKVRH---KSASNGSKTDTEE 1794

Query: 268  RDLKRKKYLTKGDDHIQHVSTHHSKLVDSHCGLDLKSG-KEPGELLPANIPIDLNPSTSI 326
             + ++++         Q     H +    H   D   G +     LP         S   
Sbjct: 1795 EEEQQQQ-------KEQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKT 1847

Query: 327  CSFCQSS-ETSEATGPMLHYANGKSVIGDAAMQPNVIHVHRCCVDWAPQVYFVDETCKNL 385
             S  + S  T+   GP L        I +  +  N   VH  C+ WA  +Y V      L
Sbjct: 1848 VSDTKPSVPTTSEGGPELELQ-----IPELPLDSNEFWVHEGCILWANGIYLVCGRLYGL 1902

Query: 386  KAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAMDVSTCRWDQEKYLLLCPVHSN 445
            +  +    ++KCS C   GA LGCY K C   YH PCA+D + C   +E + + CP H  
Sbjct: 1903 QEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAID-ADCLLHEENFSVRCPKHKC 1961

Query: 446  AKFPHEKSRPKKQATQE 462
               P +    K   + E
Sbjct: 1962 PLPPLQNKTAKGSLSTE 1978


>TF20_HUMAN (Q9UGU0) Transcription factor 20 (Stromelysin 1
            PDGF-responsive element-binding protein) (SPRE-binding
            protein) (Nuclear factor SPBP) (AR1)
          Length = 1960

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 75/303 (24%), Positives = 115/303 (37%), Gaps = 33/303 (10%)

Query: 154  MHVKPEELEMSSGGRAGFRNDVKPYPMQRSRVEIGDYVEMDVNQVTQAAVYSPPFCDTKG 213
            ++ + EE      GR G R+   P     S+        +    VT+++V     C   G
Sbjct: 1650 INAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVCCLCG 1709

Query: 214  SDNDCSEL-DSDHPFNPE-----ILENSSLKRASTGKGNLKERKSQFRSESSASETDKPT 267
                   + D   PF P+     + +N   KRA+  +  +K R     S  S ++T++  
Sbjct: 1710 KWASYRNMGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKS-ASNGSKTDTEEEE 1768

Query: 268  RDLKRKKYLTKGDDHIQHVSTHHSKLVDSHCG-------LDLKSGKEPGELLPANIPIDL 320
               +++K       H +    H S+     CG         L   K   E       +D 
Sbjct: 1769 EQQQQQKEQRSLAAHPRFKRRHRSE----DCGGGPRSLSRGLPCKKAATEGSSEKTVLDS 1824

Query: 321  NPSTSICSFCQSSETSEATGPMLHYANGKSVIGDAAMQPNVIHVHRCCVDWAPQVYFVDE 380
             PS           T+   GP L        I +  +  N   VH  C+ WA  +Y V  
Sbjct: 1825 KPSVP---------TTSEGGPELELQ-----IPELPLDSNEFWVHEGCILWANGIYLVCG 1870

Query: 381  TCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAMDVSTCRWDQEKYLLLC 440
                L+  +    ++KCS C   GA LGCY K C   YH PCA+D + C   +E + + C
Sbjct: 1871 RLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAID-ADCLLHEENFSVRC 1929

Query: 441  PVH 443
            P H
Sbjct: 1930 PKH 1932


>PHF6_MOUSE (Q9D4J7) PHD finger protein 6
          Length = 364

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 50/200 (25%), Positives = 81/200 (40%), Gaps = 18/200 (9%)

Query: 238 KRASTGKGNLKERKSQFRSESSASETDKPTRDLKRKKYLTKGDDHIQHVSTHHSKLVDSH 297
           K A   + +L+E  ++   E S+ +T K +R  + +K   KG           S+   SH
Sbjct: 133 KTAHNSEADLEESFNEHELEPSSPKTKKKSRKGRPRKTNLKG-------LPEDSRSTSSH 185

Query: 298 CGLDLKSGKEPGELLPANIPIDLNPSTSICSFCQSSETSEATGPMLHYANGKSVIGDAAM 357
              +++S          + P D  P    C FC   E        LH  N K     A  
Sbjct: 186 GTDEMESSSYRDRSPHRSSPNDTRPK---CGFCHVGEEENEARGKLHIFNAKKAA--AHY 240

Query: 358 QPNVIHVHRCCVDWAPQVYFVDETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRT 417
           +  +       +    +  F D   K +  E+ RG ++KC+ C   GA +GC +K+C +T
Sbjct: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300

Query: 418 YHVPCAMDVSTCRWDQEKYL 437
           YH  C +       D+ KY+
Sbjct: 301 YHYHCGVQ------DKAKYI 314



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 44/147 (29%), Positives = 66/147 (43%), Gaps = 24/147 (16%)

Query: 327 CSFCQSSETSEATGPMLHYANGKSVIGDAAMQPNVIHVHRCCVDWAPQVYFVDE------ 380
           C FC+S+   E  G +L   N K           V   H+C +  +  V    +      
Sbjct: 17  CGFCKSNRDKEC-GQLLISENQK-----------VAAHHKCMLFSSALVSSHSDNESLGG 64

Query: 381 -TCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAM-DVSTCRW--DQEKY 436
            + ++++ E+ RG KL CS C   GA +GC VK+C RTYH  CA+ D +  R    Q  Y
Sbjct: 65  FSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIY 124

Query: 437 LLLCPVHSNAKFPHEKSRPKKQATQEH 463
           ++ C  H   K  H      +++  EH
Sbjct: 125 MVYCRKHK--KTAHNSEADLEESFNEH 149


>PHF6_HUMAN (Q8IWS0) PHD finger protein 6 (PHD-like zinc finger
           protein)
          Length = 365

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 59/249 (23%), Positives = 96/249 (37%), Gaps = 34/249 (13%)

Query: 238 KRASTGKGNLKERKSQFRSESSASETDKPTRDLKRKKYLTKGDDHIQHVSTHHSKLVDSH 297
           K A   + +L+E  ++   E S+ ++ K +R  + +K   KG        +  ++   SH
Sbjct: 133 KTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKG-------LSEDTRSTSSH 185

Query: 298 CGLDLKSGKEPGELLPANIPIDLNPSTSICSFCQSSETSEATGPMLHYANGKSVIGDAAM 357
              +++S          + P D  P    C FC   E        LH  N K     A  
Sbjct: 186 GTDEMESSSYRDRSPHRSSPSDTRPK---CGFCHVGEEENEARGKLHIFNAKKAA--AHY 240

Query: 358 QPNVIHVHRCCVDWAPQVYFVDETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRT 417
           +  +       +    +  F D   K +  E+ RG ++KC+ C   GA +GC +K+C +T
Sbjct: 241 KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 300

Query: 418 YHVPCAMDVSTCRWDQEKYL---------LLCPVHSNAKFPHE-------KSRPKKQATQ 461
           YH  C +       D+ KY+         L C  HS      E       KSR K +  Q
Sbjct: 301 YHYHCGVQ------DKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQ 354

Query: 462 EHPASAHLS 470
           +      L+
Sbjct: 355 QQLTQQQLN 363



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 44/147 (29%), Positives = 66/147 (43%), Gaps = 24/147 (16%)

Query: 327 CSFCQSSETSEATGPMLHYANGKSVIGDAAMQPNVIHVHRCCVDWAPQVYFVDE------ 380
           C FC+S+   E  G +L   N K           V   H+C +  +  V    +      
Sbjct: 17  CGFCKSNRDKEC-GQLLISENQK-----------VAAHHKCMLFSSALVSSHSDNESLGG 64

Query: 381 -TCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCAM-DVSTCRW--DQEKY 436
            + ++++ E+ RG KL CS C   GA +GC VK+C RTYH  CA+ D +  R    Q  Y
Sbjct: 65  FSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIY 124

Query: 437 LLLCPVHSNAKFPHEKSRPKKQATQEH 463
           ++ C  H   K  H      +++  EH
Sbjct: 125 MVYCRKHK--KTAHNSEADLEESFNEH 149


>RAI1_HUMAN (Q7Z5J4) Retinoic acid induced protein 1
          Length = 1906

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 364  VHRCCVDWAPQVYFVDETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCA 423
            VH  C  W   VY V      L+  +     + CS+C   GA +GC  K C  TYH PCA
Sbjct: 1824 VHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCA 1883

Query: 424  MDVSTCRWDQEKYLLLCPVH 443
             D   C + +E + L CP H
Sbjct: 1884 SDAG-CIFIEENFSLKCPKH 1902


>RAI1_MOUSE (Q61818) Retinoic acid induced protein 1
          Length = 1889

 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 364  VHRCCVDWAPQVYFVDETCKNLKAEVARGAKLKCSTCGLKGAALGCYVKSCKRTYHVPCA 423
            VH  C  W   VY V      L+  +     + C++C   GA + C  K C  TYH PCA
Sbjct: 1806 VHEACAVWTSGVYLVAGKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCA 1865

Query: 424  MDVSTCRWDQEKYLLLCPVH 443
             D   C + +E + L CP H
Sbjct: 1866 NDTG-CTFIEENFTLKCPKH 1884


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.316    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,089,006
Number of Sequences: 164201
Number of extensions: 3726083
Number of successful extensions: 9607
Number of sequences better than 10.0: 209
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 9341
Number of HSP's gapped (non-prelim): 289
length of query: 726
length of database: 59,974,054
effective HSP length: 118
effective length of query: 608
effective length of database: 40,598,336
effective search space: 24683788288
effective search space used: 24683788288
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)