BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0075.5
(667 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment) 65 4e-10
GOB1_HUMAN (Q14789) Golgi autoantigen, golgin subfamily B member... 62 6e-09
MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (S... 57 1e-07
MYSN_ACACA (P05659) Myosin II heavy chain, non muscle 56 3e-07
GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member... 55 8e-07
MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper prote... 54 1e-06
MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (S... 54 1e-06
CAG5_HUMAN (O15320) CTAGE family member 5 (Meningioma-expressed ... 53 2e-06
MYHB_MOUSE (O08638) Myosin heavy chain, smooth muscle isoform (S... 53 3e-06
USO1_YEAST (P25386) Intracellular protein transport protein USO1 51 1e-05
RA50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase 51 1e-05
RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase 51 1e-05
PCP1_SCHPO (Q92351) Spindle pole body protein pcp1 51 1e-05
CING_XENLA (Q9PTD7) Cingulin 50 1e-05
DYNA_HUMAN (Q14203) Dynactin 1 (150 kDa dynein-associated polype... 50 2e-05
GCC2_MOUSE (Q8CHG3) GRIP and coiled-coil domain-containing prote... 50 2e-05
MYS2_DICDI (P08799) Myosin II heavy chain, non muscle 49 3e-05
DYNA_MOUSE (O08788) Dynactin 1 (150 kDa dynein-associated polype... 49 4e-05
MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B) 49 6e-05
PUMA_PARUN (O61308) 227 kDa spindle- and centromere-associated p... 48 9e-05
>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)
Length = 539
Score = 65.5 bits (158), Expect = 4e-10
Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%)
Query: 115 RMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKR 174
+ +LQ ++ ET K N D+ I + IR + M+ EK + + L R
Sbjct: 156 KTEELQSNISRLETEKQNRDKQIDTLNEDIRKQDETI----SKMNAEK--KHVDEELKDR 209
Query: 175 FDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEED-EDQREK 233
+ A ++ +++ K ++L S++ E L + K K E D +D R+K
Sbjct: 210 TEQLQAAEDKCNNLNKTK-NKLESSIREIEQDLKKEKDSKMKLEKEKKKVESDLKDNRDK 268
Query: 234 --DTDANIAEAVSLLNKALKSLGRMSNTNV-LDNVSDNVKNTEFQLKDKHENDTTKAIHV 290
+T+ + E L+ K KS+ + N L++ ++ +L K E + +
Sbjct: 269 LSETETRLKETQDLVTKREKSISDLENAKEGLESQISQLQRKIQELLAKIEELEEELENE 328
Query: 291 KALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNN 350
+ L K + + EEL + + G+K E L E + L N
Sbjct: 329 RKLRQKSELQRKELESRIEELQDQLETAGGATSAQVEVGKKREAECNRLRKEIEALNIAN 388
Query: 351 SSLQEEVK-----TISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMM------- 398
+ +K TI++++EENE ++ AKL++E + LN++L K S+ +
Sbjct: 389 DAAISAIKAKTNATIAEIQEENEAMKKAKAKLEKEKSALNNELNETKNSLDQIKKQKTNS 448
Query: 399 NKSTNVLEE-ILEVGKTVGDMEGIGFSYKSANKSASSE 435
+K++ +LEE I E+ + ++ + +S N +SE
Sbjct: 449 DKNSRMLEEQINELNSKLAQVDELHSQSESKNSKVNSE 486
Score = 43.5 bits (101), Expect = 0.002
Identities = 70/332 (21%), Positives = 138/332 (41%), Gaps = 48/332 (14%)
Query: 105 KTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLA 164
KT ++ S +R + L + MK+ +++ E DL ++ + +SE +
Sbjct: 225 KTKNKLESSIREIEQDLKKEKDSKMKLEKEKKKVE-----SDLKDNR----DKLSETETR 275
Query: 165 RKILRSLPKRFDMKVTAIEEAQD-----ISNI--KVDELIGSLQTFEMSLNGRSEKKAKS 217
K + L + + ++ +E A++ IS + K+ EL+ ++ E L + + KS
Sbjct: 276 LKETQDLVTKREKSISDLENAKEGLESQISQLQRKIQELLAKIEELEEELENERKLRQKS 335
Query: 218 IT----FVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTE 273
S EE +DQ E A A+ V + K R+ N++++ +
Sbjct: 336 ELQRKELESRIEELQDQLETAGGATSAQ-VEVGKKREAECNRLRKEIEALNIANDAAISA 394
Query: 274 FQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGE--K 331
+ K N T I +E E ++ K L K E+S + E +
Sbjct: 395 IKAKT---NATIAEIQ-----------------EENEAMKKAKAKLEK-EKSALNNELNE 433
Query: 332 MRKEVKDLIAEKKQLQSNNSSLQEEVKTI-SKLREENE---KLQITNAKLQEEVTLLNSK 387
+ + + +K N+ L+E++ + SKL + +E + + N+K+ E+ LNS+
Sbjct: 434 TKNSLDQIKKQKTNSDKNSRMLEEQINELNSKLAQVDELHSQSESKNSKVNSELLALNSQ 493
Query: 388 LEGMKKSIRMMNKSTNVLEEILEVGKTVGDME 419
L + ++ + K+ LE L K + E
Sbjct: 494 LSESEHNLGIATKNIKTLESQLAESKNFNEAE 525
Score = 42.0 bits (97), Expect = 0.005
Identities = 46/202 (22%), Positives = 87/202 (42%), Gaps = 29/202 (14%)
Query: 225 EEDEDQREKDTDAN------IAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKD 278
E ++Q +KD +A + EA++ K SL + T+ L + D + N + +KD
Sbjct: 60 EAAKEQLKKDAEAKKKMEEELTEAMAQKEKLYASL--QAETDRLITIEDKLLNLQ-TVKD 116
Query: 279 KHENDTTKAIHVKALIGKCYSDAESSDGDEEE---LVETYKLLLAKWEESCMYGEKMRKE 335
K E+ +A+ E DG+E L E + K +E E+++
Sbjct: 117 KLESSLNEAL-------------EKLDGEEHSVLVLEEKIQEAEEKIDELTEKTEELQSN 163
Query: 336 VKDLIAEK----KQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGM 391
+ L EK KQ+ + N ++++ +TISK+ E + + E++ K +
Sbjct: 164 ISRLETEKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEELKDRTEQLQAAEDKCNNL 223
Query: 392 KKSIRMMNKSTNVLEEILEVGK 413
K+ + S +E+ L+ K
Sbjct: 224 NKTKNKLESSIREIEQDLKKEK 245
Score = 37.0 bits (84), Expect = 0.17
Identities = 29/110 (26%), Positives = 55/110 (49%), Gaps = 6/110 (5%)
Query: 301 AESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTI 360
AE +EE +E K L K E+ +KM +E+ + +A+K++L + SLQ E +
Sbjct: 48 AEDEMRAKEEELEAAKEQLKKDAEA---KKKMEEELTEAMAQKEKLYA---SLQAETDRL 101
Query: 361 SKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILE 410
+ ++ LQ KL+ + KL+G + S+ ++ + EE ++
Sbjct: 102 ITIEDKLLNLQTVKDKLESSLNEALEKLDGEEHSVLVLEEKIQEAEEKID 151
>GOB1_HUMAN (Q14789) Golgi autoantigen, golgin subfamily B member 1
(Giantin) (Macrogolgin) (Golgi complex-associated
protein, 372-kDa) (GCP372)
Length = 3259
Score = 61.6 bits (148), Expect = 6e-09
Identities = 65/330 (19%), Positives = 146/330 (43%), Gaps = 31/330 (9%)
Query: 119 LQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPM-SEEKLARKILRSLPKRFDM 177
++ L TQ E DE I + + + ++ +GE +++++ RK+ +L R +
Sbjct: 1436 IKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEA 1495
Query: 178 --KVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDT 235
+ +++E ++ ++ L SL E ++ ++++K + ++ +E+ D+ +
Sbjct: 1496 LKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEM 1555
Query: 236 DANIAEAVSLLN-----------------KALKSLGRMSNTNVLDNVSDNVKNTEFQ--- 275
D ++ E SL + K +K + + ++ + ++ K+ E Q
Sbjct: 1556 DRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEY 1615
Query: 276 --LKDKHENDTTKAIHVKALIGKCYSDAESSDGD----EEELVETYKLLLAKWEESCMYG 329
L +EN + +A ++ ++ + + G E ET K L +E
Sbjct: 1616 EILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK 1675
Query: 330 EKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREE-NEKLQITNAKLQEEVTLLNSKL 388
EKMRK K + +L+ N L+ EV +E E L +NA ++EE+ + +
Sbjct: 1676 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1735
Query: 389 EGMKKSIR-MMNKSTNVLEEILEVGKTVGD 417
E + K + +M++ ++ EE+ ++ + D
Sbjct: 1736 ETLSKKFQSLMSEKDSLSEEVQDLKHQIED 1765
Score = 43.9 bits (102), Expect = 0.001
Identities = 66/329 (20%), Positives = 148/329 (44%), Gaps = 50/329 (15%)
Query: 112 SKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIR--DLANSTFALGEPMSEEKLARKILR 169
S+++ K QL K E + E +R + D+ NS F+ + ++ + +R++
Sbjct: 2312 SELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTS 2371
Query: 170 SLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDED 229
L + +MK E + IS + E ++Q L + +K+ K + + + EE+E+
Sbjct: 2372 RLHEEINMK-----EQKIISLLSGKE--EAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2424
Query: 230 QREKDTDANIAEAVSLLNKALKSLGR------------MSNTNVLDNVSDNVKNTEFQLK 277
++ + + + L + LK++ + + + + L N D + QL+
Sbjct: 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE 2484
Query: 278 DKH----------------ENDTTKAIHVKALIGKCYSDAESSDGD--EEELVETYKLLL 319
++H EN+ K ++ L + + D +S+ + EL++ + L
Sbjct: 2485 ERHLSIILEKDQLIQEAAAENNKLKE-EIRGL--RSHMDDLNSENAKLDAELIQYREDL- 2540
Query: 320 AKWEESCMYGEKMRKEVKDL-IAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQ 378
+ + +K++ ++ + + K+L++ + L+E++K + E NE L+ + LQ
Sbjct: 2541 ---NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLK---ESEEANEDLRRSFNALQ 2594
Query: 379 EEVTLLNSKLEGMKKSIRMMNKSTNVLEE 407
EE L+ ++E +K SI + + L+E
Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVTALQE 2623
Score = 41.2 bits (95), Expect = 0.009
Identities = 52/252 (20%), Positives = 109/252 (42%), Gaps = 22/252 (8%)
Query: 121 LLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVT 180
LLT Q ++ + + + +L + E + L R + L + +
Sbjct: 793 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSE---QSTLIRSLQSQLQNKESEVLE 849
Query: 181 AIEEAQDISNIKVDELIGSLQTFEMSLNGRSE---KKAKSITFVSNTEEDEDQREKDTDA 237
E + IS+ KV+EL +L E+ + + +K + + + T E++DQ+ +
Sbjct: 850 GAERVRHISS-KVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISF 908
Query: 238 NIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKC 297
++ E + LN+ SLG T L + + E K++ E D + +K +
Sbjct: 909 SMTEKMVQLNEEKFSLGVEIKT--LKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEM 966
Query: 298 YSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEV 357
+ S +EEL + LL + E+ +++++ + +K+L S L+EE
Sbjct: 967 SPAGQIS---KEELQHEFDLLKKE-------NEQRKRKLQAALINRKELLQRVSRLEEE- 1015
Query: 358 KTISKLREENEK 369
++ L++E++K
Sbjct: 1016 --LANLKDESKK 1025
Score = 35.0 bits (79), Expect = 0.64
Identities = 78/416 (18%), Positives = 161/416 (37%), Gaps = 34/416 (8%)
Query: 106 TAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLAR 165
+A +G + V K QL + E K+ + + + + F L E ++++ L
Sbjct: 1296 SALQGGTSVAQIKAQL--KEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEI 1353
Query: 166 KILRSLPKRFDMKVTAIEEAQDISNIKVDEL--IGSLQTFEMSLNGRSEKKAKSITFVSN 223
+ L+++ ++ ++++ + S +++ L + LQ L KK + ++++S
Sbjct: 1354 ESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSG 1413
Query: 224 TEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSD-NVKNTEFQLKDKHEN 282
+++ I E L+ KAL + M + + V+ E + K +
Sbjct: 1414 QLSEKEAALTKIQTEIIEQEDLI-KALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIG 1472
Query: 283 DTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAE 342
+ ++A K I + A S +E L E L EE + + + K L
Sbjct: 1473 EESRA---KQQIQRKLQAALISR--KEALKENKSLQ----EELSLARGTIERLTKSLADV 1523
Query: 343 KKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKST 402
+ Q+ + N + ++ L+EE +KL + E L+S E +K ++ + +
Sbjct: 1524 ESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDK 1583
Query: 403 NVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQPMSDPMLHHSVRHVYPQFRKSK 462
L + +E S KS+ + S+E Q K L + +
Sbjct: 1584 EKLVKEIE-------------SLKSSKIAESTEWQEKH----KELQKEYEILLQSYENVS 1626
Query: 463 KSTWRCHHCGKLGHIRPYCYKLYGYPQSHDQPRTNPQVAPTRKEWKPSGLKEKEKK 518
R H + +R +LYG +S + + + E + +KEK +K
Sbjct: 1627 NEAERIQHV--VEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1680
Score = 35.0 bits (79), Expect = 0.64
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 7/71 (9%)
Query: 323 EESCMYGEKMRKEVKDLIAEKK-QLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEV 381
+E Y E++ E+KD+I +K QLQ + +LQEE K + K++ + ++
Sbjct: 51 QERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKA------ADNKIKKLKLHAKAKL 104
Query: 382 TLLNSKLEGMK 392
T LN +E MK
Sbjct: 105 TSLNKYIEEMK 115
Score = 35.0 bits (79), Expect = 0.64
Identities = 56/275 (20%), Positives = 107/275 (38%), Gaps = 23/275 (8%)
Query: 116 MSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRF 175
+ +L LL + + + D S+ E + AL E ++E+K K+++ +
Sbjct: 1538 LGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL-EGLTEDK--EKLVKEIESLK 1594
Query: 176 DMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDT 235
K+ E Q+ E LQ++E +++ +E+ + V +++ + + T
Sbjct: 1595 SSKIAESTEWQEKHKELQKEYEILLQSYE-NVSNEAERIQHVVEAVRQEKQELYGKLRST 1653
Query: 236 DANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIG 295
+AN E L +A + + M S K E + END +A
Sbjct: 1654 EANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE----EENDRLRA-------- 1701
Query: 296 KCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQE 355
+ + +E +ET A +E E+++ E + L + + L S SL E
Sbjct: 1702 ----EVHPAGDTAKECMETLLSSNASMKEEL---ERVKMEYETLSKKFQSLMSEKDSLSE 1754
Query: 356 EVKTISKLREENEKLQITNAKLQEEVTLLNSKLEG 390
EV+ + E+N Q ++ N EG
Sbjct: 1755 EVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEG 1789
Score = 34.7 bits (78), Expect = 0.83
Identities = 60/288 (20%), Positives = 122/288 (41%), Gaps = 33/288 (11%)
Query: 102 EILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEE 161
E+ HE + + LL+ + E +++ E + I++L N +S+E
Sbjct: 2368 ELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENL-------LSQE 2420
Query: 162 KLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELI--GSLQTFEMSLNGRSEKKAKSIT 219
+ +L K+ K + E + IK + + L +F S++ + + +
Sbjct: 2421 EEENIVLEEENKKAVDKTNQLMET--LKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVG 2478
Query: 220 FVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDK 279
EE + D I EA + NK LK R +++ D S+N K ++
Sbjct: 2479 DYQQLEERHLSIILEKDQLIQEAAAENNK-LKEEIRGLRSHMDDLNSENAKLDAELIQ-- 2535
Query: 280 HENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDL 339
+ D + I +K D +++L+E L + +E K+ +++K+
Sbjct: 2536 YREDLNQVITIK-------------DSQQKQLLEVQ---LQQNKELENKYAKLEEKLKES 2579
Query: 340 IAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSK 387
+ L+ + ++LQEE + +SK E E L+++ ++L +VT L +
Sbjct: 2580 EEANEDLRRSFNALQEEKQDLSK---EIESLKVSISQLTRQVTALQEE 2624
Score = 32.3 bits (72), Expect = 4.1
Identities = 44/254 (17%), Positives = 103/254 (40%), Gaps = 39/254 (15%)
Query: 168 LRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSE-------KKAKSITF 220
L+S + D ++A+ + +++ L + E++ + E +KAK I
Sbjct: 661 LKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEI-- 718
Query: 221 VSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDK- 279
SN + ++ +K+ D N + +L + + L ++ +++ + VK E L +
Sbjct: 719 -SNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAE 777
Query: 280 ------------HENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCM 327
H+N T+ IH ++ +A+S D E L + ++ E
Sbjct: 778 RQRRLDYESQTAHDNLLTEQIHSLSI------EAKSKDVKIEVLQNELDDVQLQFSEQST 831
Query: 328 YGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSK 387
++ QLQ+ S + E + + + + E+L ++ + E+T ++
Sbjct: 832 LIRSLQS----------QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQL 881
Query: 388 LEGMKKSIRMMNKS 401
L K+ + + ++
Sbjct: 882 LLEKKRDVETLQQT 895
Score = 31.6 bits (70), Expect = 7.0
Identities = 58/256 (22%), Positives = 107/256 (41%), Gaps = 27/256 (10%)
Query: 163 LARKILRSLPKRFDMKVTAIEEAQDISNIKVD---ELIGSLQTFEMSL------NGRSEK 213
L ++I L + +K TA EE D+ ++ EL GS+ + + N E
Sbjct: 1897 LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLES 1956
Query: 214 KAKSIT-FVSNTEEDEDQREKD---TDANIA-EAVSLLNKALKSLGRMSNTNVLDNV--- 265
+ K++ VS EE++ Q K+ ++ I E + + A K G S+ L +
Sbjct: 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKE 2016
Query: 266 -SDNVKNTEFQLKDKHENDTTKAIHVKALI---GKCYSDAESSDGDEEELVETYKLLLAK 321
VK + E + VKAL + D E + + + VE K A+
Sbjct: 2017 KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2076
Query: 322 WEESCMYGEKMRKEVKDLIAE----KKQLQSNNSSLQEEVKTISKLREENEKLQITNAKL 377
+ + + E ++A+ KK+LQSN S++ ++K K + +L+ K
Sbjct: 2077 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMK--QKDEDLERRLEQAEEKH 2134
Query: 378 QEEVTLLNSKLEGMKK 393
+E + KL+ +++
Sbjct: 2135 LKEKKNMQEKLDALRR 2150
>MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 57.4 bits (137), Expect = 1e-07
Identities = 83/370 (22%), Positives = 146/370 (39%), Gaps = 50/370 (13%)
Query: 95 TVAKEAWEILKTAHEG-TSKVRMSKLQLLTT------QFETMKMNEDESIYEFHMRIRDL 147
TV K+A + +HE ++R Q + QF+ K N D++ DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Query: 148 ANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSL 207
A LG+ E + +K L + + K + E A+ N KV +L +++ L
Sbjct: 1237 AGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1296
Query: 208 N---GRSEKKAKSITFVSNTEEDED---QREKDTDANIAEAVSLLNKALKSLGRM--SNT 259
N G++ K AK + +S+ +D Q E N++ + L + SL
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 260 NVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKAL-IGK-------------------CYS 299
N+ ++ QL D + A V+AL GK Y
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416
Query: 300 DAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNS-------- 351
E + ++ ++ + L + EK +++ L+AE+K + S +
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 1476
Query: 352 -SLQEEVKTISKLR------EENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNV 404
+ ++E K +S R E E+L+ TN L+ E+ L S + + K++ + KS
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1536
Query: 405 LEEILEVGKT 414
LE +E KT
Sbjct: 1537 LETQMEEMKT 1546
Score = 43.9 bits (102), Expect = 0.001
Identities = 56/269 (20%), Positives = 127/269 (46%), Gaps = 30/269 (11%)
Query: 127 ETMKMNEDESIYEFHM--RIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVT-AIE 183
+T ++ ++E+ + ++ ++R L +L + + EE A++ L +++++ + +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 184 EAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDA------ 237
+ QD ++ V+ L + F+ + +++ + E+ +++ +++ D
Sbjct: 1379 KLQDFAST-VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 238 NIAEAVSLLNKALKSLGRM--SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIG 295
N + VS L K + ++ N+ +D E + ++K TKA+ + +
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE----TKALSLARAL- 1492
Query: 296 KCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQE 355
E + +EEL T K+L A+ E+ + + K V +L K+ L++ E
Sbjct: 1493 ------EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ----ME 1542
Query: 356 EVKTISKLREENEKLQIT-NAKLQEEVTL 383
E+KT +L E ++LQ T +AKL+ EV +
Sbjct: 1543 EMKT--QLEELEDELQATEDAKLRLEVNM 1569
Score = 42.7 bits (99), Expect = 0.003
Identities = 76/345 (22%), Positives = 140/345 (40%), Gaps = 55/345 (15%)
Query: 104 LKTAHEGTS---KVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMS- 159
LK HE +VR+ K + + E +K + +FH +I DL L ++
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 160 -EEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSI 218
EE+L + R L K A++ K+ EL G + + L+ SE+ A++
Sbjct: 1088 KEEELQAALAR-LDDEIAQKNNALK--------KIRELEGHISDLQEDLD--SERAARN- 1135
Query: 219 TFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKD 278
+ E Q+ ++ E + L L+ + LD+ + T+ +L+
Sbjct: 1136 -------KAEKQKR-----DLGEELEALKTELE--------DTLDSTA-----TQQELRA 1170
Query: 279 KHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKD 338
K E + T + KAL E + E ++ E + EE E+ ++ +
Sbjct: 1171 KREQEVT--VLKKAL-------DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 339 LIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKL-EGMKKSIRM 397
L K+ L+ N+ L E++ + + ++E E KL+ +V L SK +G + +
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEH---KKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 398 MNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQPM 442
+K + E+ V + + EG S SS+ Q Q +
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1323
Score = 41.2 bits (95), Expect = 0.009
Identities = 43/276 (15%), Positives = 106/276 (37%), Gaps = 23/276 (8%)
Query: 139 EFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIG 198
+F + D S + E + K L + + + A E A+ ++++ +EL
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1715
Query: 199 SLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSN 258
L + N ++K + ++ EE+ ++ + N+ + KA + ++SN
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ----GNMEAMSDRVRKATQQAEQLSN 1771
Query: 259 TNVLDNVSDNVKNTEFQLKDKHENDTTKAIH----------------VKALIGKCYSDAE 302
+ + + Q ++ + +H ++A I + E
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1831
Query: 303 SSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISK 362
+++ ++ K K +E + E RK + K+Q + N+ +++ + + +
Sbjct: 1832 QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY---KEQAEKGNARVKQLKRQLEE 1888
Query: 363 LREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMM 398
EE++++ KLQ E+ E M + + +
Sbjct: 1889 AEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 34.3 bits (77), Expect = 1.1
Identities = 61/305 (20%), Positives = 130/305 (42%), Gaps = 48/305 (15%)
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEE---AQDISNIKVDELIGSL 200
+ DL +S +G+ + E + +++ L + + ++ +E+ A + + ++++ + +L
Sbjct: 1513 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1572
Query: 201 Q-TFEMSLNGR---SEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSL--- 253
+ FE L R +E+K + + + E E + E+ A A A L LK L
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 254 ------GRMSNTNVLDNVSDNVKNTEFQLKDKH----------ENDTTKAIHVKALIGKC 297
GR L + +K+ + +L+D + + KA ++A + +
Sbjct: 1633 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 298 YSDA-------ESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVK--DLIAEKKQLQS 348
D + +D ++EEL E L+ + + EK R E + L E ++ Q
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSG--RNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 349 NNSSLQEEVKTISKLREE-----------NEKLQITNAKLQEEVTLLNSKLEGMKKSIRM 397
N ++ + V+ ++ E+ +K + +L+ + L SKL M+ +++
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Query: 398 MNKST 402
KST
Sbjct: 1811 KFKST 1815
Score = 33.9 bits (76), Expect = 1.4
Identities = 28/105 (26%), Positives = 54/105 (50%), Gaps = 8/105 (7%)
Query: 308 EEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREEN 367
++EL E + A+ EE G++++ E K + + L+ L+EE KL+ E
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ---LEEEEAARQKLQLEK 973
Query: 368 EKLQITNAKLQEEVTLL---NSKLEGMKKSI--RMMNKSTNVLEE 407
+ KL++E+ ++ N+KL +K + R+ + +TN+ EE
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
>MYSN_ACACA (P05659) Myosin II heavy chain, non muscle
Length = 1509
Score = 55.8 bits (133), Expect = 3e-07
Identities = 66/303 (21%), Positives = 124/303 (40%), Gaps = 37/303 (12%)
Query: 132 NEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNI 191
N + I + +++DL AL + ++ +++ + + + A++ +
Sbjct: 853 NFQKEIDDLKKQVKDLEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALK-------L 905
Query: 192 KVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALK 251
K+ +L G E N +KK + E+E Q E +I E L
Sbjct: 906 KILDLEGEKADLEED-NALLQKKVAGL-------EEELQEETSASNDILEQKRKLEAEKG 957
Query: 252 SLGRM-----SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKAL---IGKCYSDAES 303
L N L V++ +L+DK+E++ +K + + + +
Sbjct: 958 ELKASLEEEERNRKALQEAKTKVESERNELQDKYEDEAAAHDSLKKKEEDLSRELRETKD 1017
Query: 304 SDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEV-KTISK 362
+ D E + ET + L E + +R E+ D+ A K QL+ SL+EE+ +T ++
Sbjct: 1018 ALADAENISETLRSKLKNTERGA---DDVRNELDDVTATKLQLEKTKKSLEEELAQTRAQ 1074
Query: 363 LREENEKLQITNAKLQE----------EVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVG 412
L EE + ++K ++ EV L SKL +KS++ L+E LE
Sbjct: 1075 LEEEKSGKEAASSKAKQLGQQLEDARSEVDSLKSKLSAAEKSLKTAKDQNRDLDEQLEDE 1134
Query: 413 KTV 415
+TV
Sbjct: 1135 RTV 1137
Score = 38.5 bits (88), Expect = 0.057
Identities = 71/363 (19%), Positives = 143/363 (38%), Gaps = 38/363 (10%)
Query: 104 LKTAHEGTSKVRMSKLQLLTT--QFETMKMNEDESIYEFHMRIRDLANSTFA-------L 154
LK G VR + T Q E K + +E + + ++ + + A L
Sbjct: 1033 LKNTERGADDVRNELDDVTATKLQLEKTKKSLEEELAQTRAQLEEEKSGKEAASSKAKQL 1092
Query: 155 GEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKK 214
G+ + + AR + SL + +++ A+D N +DE + +T +++ +KK
Sbjct: 1093 GQQLED---ARSEVDSLKSKLSAAEKSLKTAKD-QNRDLDEQLEDERTVRANVD--KQKK 1146
Query: 215 A---------KSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNV 265
A +T + + + K + E L +A S R+ N
Sbjct: 1147 ALEAKLTELEDQVTALDGQKNAAAAQAKTLKTQVDETKRRLEEAEASAARLEKER--KNA 1204
Query: 266 SDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSD---GDEEELVETYKLLLAKW 322
D V L + ++ + + I + S+ E++ G E V+ + L +
Sbjct: 1205 LDEVAQLTADLDAERDSGAQQRRKLNTRISELQSELENAPKTGGASSEEVKRLEGELERL 1264
Query: 323 EESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVT 382
EE + ++ R A +K L N L+E + +N+KL N KL+ ++
Sbjct: 1265 EEELLTAQEARA------AAEKNLDKANLELEELRQEADDAARDNDKLVKDNRKLKADLD 1318
Query: 383 LLNSKLEGMKKSIRMMNKST-NVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQP 441
+LE + + + S+ +L EI E+ K V + K+ ++ A+ +++ +
Sbjct: 1319 EARIQLEEEQDAKSHADSSSRRLLAEIEELKKRVA--KETSDKQKAQDQKANYQRENESL 1376
Query: 442 MSD 444
+D
Sbjct: 1377 KAD 1379
Score = 34.7 bits (78), Expect = 0.83
Identities = 76/367 (20%), Positives = 143/367 (38%), Gaps = 48/367 (13%)
Query: 38 KAIVKGWKHPVIASTTELKPEDKWTKKEDDEALGNSKALNVIFNGVDKNMFRLINTCTVA 97
+A V K + A TEL+ + + + A +K L VD+ RL
Sbjct: 1138 RANVDKQKKALEAKLTELEDQVTALDGQKNAAAAQAKTLKT---QVDETKRRL------- 1187
Query: 98 KEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLAN---STFAL 154
E E E K + ++ LT + + + + + + RI +L + +
Sbjct: 1188 -EEAEASAARLEKERKNALDEVAQLTADLDAERDSGAQQRRKLNTRISELQSELENAPKT 1246
Query: 155 GEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKK 214
G SEE K L +R + ++ +EA+ + +D+ L+ + +
Sbjct: 1247 GGASSEEV---KRLEGELERLEEELLTAQEARAAAEKNLDKANLELEELRQEADDAARDN 1303
Query: 215 AKSITFVSNTEEDED----QREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVK 270
K + + D D Q E++ DA + A S + L + + V SD K
Sbjct: 1304 DKLVKDNRKLKADLDEARIQLEEEQDAK-SHADSSSRRLLAEIEELKK-RVAKETSDKQK 1361
Query: 271 NTEFQLKDKHENDTTKAIH----------------VKALIGKCYSDAESSDGDEEELVET 314
+ + + EN++ KA ++A + S +S +E+ VE
Sbjct: 1362 AQDQKANYQRENESLKADRDSIERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVE- 1420
Query: 315 YKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITN 374
A E + ++ R+ ++ L L+S+ L++E I L E+N++LQ
Sbjct: 1421 -----ANRELKKVVLDRERQSLESLSKFNSALESDKQILEDE---IGDLHEKNKQLQAKI 1472
Query: 375 AKLQEEV 381
A+LQ+E+
Sbjct: 1473 AQLQDEI 1479
Score = 32.7 bits (73), Expect = 3.2
Identities = 44/199 (22%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 238 NIAEAVSLLNKALKSLGR-MSNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGK 296
N + + L K +K L + ++ + D K + DK E D A+ +K L
Sbjct: 853 NFQKEIDDLKKQVKDLEKELAALKDANAKLDKEKQLAEEDADKLEKDLA-ALKLKIL--- 908
Query: 297 CYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNN----SS 352
D E D EE + +A EE ++ D++ +K++L++ +S
Sbjct: 909 ---DLEGEKADLEEDNALLQKKVAGLEEEL---QEETSASNDILEQKRKLEAEKGELKAS 962
Query: 353 LQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVG 412
L+EE + L+E K++ +LQ++ + + +KK K ++ E+ E
Sbjct: 963 LEEEERNRKALQEAKTKVESERNELQDKYEDEAAAHDSLKK------KEEDLSRELRETK 1016
Query: 413 KTVGDMEGIGFSYKSANKS 431
+ D E I + +S K+
Sbjct: 1017 DALADAENISETLRSKLKN 1035
>GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member 4
(Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1
protein)
Length = 2230
Score = 54.7 bits (130), Expect = 8e-07
Identities = 94/419 (22%), Positives = 180/419 (42%), Gaps = 60/419 (14%)
Query: 63 KKEDDEALGNSKALNVIFNGVDKNMFRLINTCTVAKEAWEILKTAHEGTSKVRMSKLQLL 122
+K E SK L V +KN T V K E+ H+ + + KLQ+L
Sbjct: 577 EKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMVEKHKTELESLKHQQDA-LWTEKLQVL 634
Query: 123 TTQFET-MKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTA 181
Q++T M+ ++ E ++D A E M+E+ L ++ D+K T
Sbjct: 635 KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTL---------EKLDVKQTE 685
Query: 182 IEE-AQDISNI-----KVDELIGSL--QTFEMSLNGRSEKKAKSITFVSNTEEDEDQREK 233
+E + ++S + K++E + L QT +M + E +AK ++ ++ D K
Sbjct: 686 LESLSSELSEVLKARHKLEEELSVLKDQTDKM----KQELEAKMDEQKNHHQQQVDSIIK 741
Query: 234 DTDANIAEAVSLLNKALKSLGRM--SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVK 291
+ + +I L + L + L +V+N E +K + E + +A K
Sbjct: 742 EHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIK-RSEGELQQA-SAK 799
Query: 292 ALIGKCYSDA--ESSDGDEEEL---------VETYKLLLAKW--------EESCMYGEKM 332
+ + Y A E + EE+L +ET ++LL K ++ C +
Sbjct: 800 LDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH 859
Query: 333 RKEVKDLIAEKKQLQSNNSSLQEEVKTI-----SKLREENEKLQITNAKLQEEVTLLNSK 387
+ +V+DL+ +QL+ NS ++++VK++ SKL + N++ + T L E+ ++
Sbjct: 860 KIQVQDLM---QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM 916
Query: 388 LEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQPMSDPM 446
EG KK I ++ + + E+ + + E +K+ K KQ + M + +
Sbjct: 917 REGQKKEIEILTQKLSAKEDSIHILN-----EEYETKFKNQEKKMEKVKQKAKEMQETL 970
Score = 39.3 bits (90), Expect = 0.034
Identities = 57/257 (22%), Positives = 108/257 (41%), Gaps = 41/257 (15%)
Query: 212 EKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKN 271
+++AK + NT + Q+EK +A + E M+ N +SD V
Sbjct: 976 DQEAKLKKELENTALELSQKEKQFNAKMLE--------------MAQANSA-GISDAVSR 1020
Query: 272 TEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESC----- 326
E K++ E+ T +H + L + + EEL E +++ L + E+
Sbjct: 1021 LETNQKEQIESLTE--VHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
Query: 327 ---MYG---EKMRKEVKDLIAEKKQLQSNNSSLQEEVKTIS-----------KLREENEK 369
++G E+M KE+ L E + + + LQE++K S KL+ EK
Sbjct: 1079 KILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEK 1138
Query: 370 LQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSAN 429
L++ K +E T L +L +K + + L L+ T + + + S++ +N
Sbjct: 1139 LEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKT--TDEEFQSLKSSHEKSN 1196
Query: 430 KSASSEKQTKQPMSDPM 446
KS + + +S+ +
Sbjct: 1197 KSLEDKSLEFKKLSEEL 1213
Score = 35.4 bits (80), Expect = 0.49
Identities = 54/274 (19%), Positives = 109/274 (39%), Gaps = 21/274 (7%)
Query: 155 GEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDI--------------SNIKVDELIGSL 200
GEP+ E+ + K L +L +R + ++ ++ ++L L
Sbjct: 268 GEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERL 327
Query: 201 QTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTN 260
Q E + +K K IT + + + +Q E+D IAE +++ L+ +
Sbjct: 328 QELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE-MKEEEIAQ 386
Query: 261 VLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLA 320
+ + E + K +++ ++ + E+ + E+ E K +
Sbjct: 387 LRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 321 KWEESCMYGEKMRKEVKDLIAE--KKQLQSNNSSLQE--EVKTISKLREENEKLQITNAK 376
EE + ++ VK + + KK + + LQ+ E + K +E +KLQ +
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 506
Query: 377 LQEE--VTLLNSKLEGMKKSIRMMNKSTNVLEEI 408
QE+ V L S+ E +K S + + LEE+
Sbjct: 507 FQEQMKVALEKSQSEYLKISQEKEQQESLALEEL 540
Score = 35.0 bits (79), Expect = 0.64
Identities = 53/249 (21%), Positives = 102/249 (40%), Gaps = 38/249 (15%)
Query: 205 MSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNV--- 261
+ L K+ + + + + +E+ +++ K +A+ V + G +N
Sbjct: 1778 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV-------EKEGGKNNIQAKQN 1830
Query: 262 LDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAK 321
L+NV D+V+ T L++K +K L E + EEL Y+ L A
Sbjct: 1831 LENVFDDVQKT---LQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1887
Query: 322 WEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEV 381
+ M G R + +L+ E + +S + +Q K +S + ++ L+ A + E
Sbjct: 1888 QQ---MDG---RNKPTELLEENTEEKSKSHLVQP--KLLSNMEAQHNDLEFKLAGAEREK 1939
Query: 382 TLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQP 441
L ++ ++K +RM+ K ++ LE+ K D E E++ KQ
Sbjct: 1940 QKLGKEIVRLQKDLRMLRKEH---QQELEILKKEYDQE--------------REEKIKQE 1982
Query: 442 MSDPMLHHS 450
D L H+
Sbjct: 1983 QEDLELKHN 1991
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein)
(Myosin II) (Non-muscle MHC)
Length = 2057
Score = 53.9 bits (128), Expect = 1e-06
Identities = 86/391 (21%), Positives = 155/391 (38%), Gaps = 49/391 (12%)
Query: 56 KPEDKWTKKEDDEALGNSKALNVIFNGVD---KNMFRLINTCTVAKEAW---EILKTAHE 109
K E+K +KED+ K + N + K L+ T+A++ E+ A E
Sbjct: 933 KQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEE 992
Query: 110 GTSKV--RMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKI 167
S++ R +L+ + + ET E+E + + L + L E + EE+ AR+
Sbjct: 993 SRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQK 1052
Query: 168 LRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEED 227
L+ + D K+ EE +++ + +L+ + E N S+ A EE+
Sbjct: 1053 LQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLA---------EEE 1103
Query: 228 EDQR-----EKDTDANIAEAVSLLNK--ALKSLGRMSNTNVLDNVSD----------NVK 270
E + + +A I E L+K + S + V+D V
Sbjct: 1104 EKAKHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVD 1163
Query: 271 NTEFQLKDKHENDTTKAIHV------KALIGKCYSDAESSDGDEEELVETYKLLLAKWE- 323
+ QL + E T + + KA K + ES + +E +E K AK E
Sbjct: 1164 EMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEK 1223
Query: 324 ---ESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENE-----KLQITNA 375
+ E ++ E+ D + Q S ++E+ T+ K EE L
Sbjct: 1224 VRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRH 1283
Query: 376 KLQEEVTLLNSKLEGMKKSIRMMNKSTNVLE 406
K +E+ +N +LE ++K+ ++ K+ LE
Sbjct: 1284 KHSQELNSINDQLENLRKAKTVLEKAKGTLE 1314
Score = 42.7 bits (99), Expect = 0.003
Identities = 71/379 (18%), Positives = 160/379 (41%), Gaps = 36/379 (9%)
Query: 42 KGWKHPVIASTTELKPEDKWTKKEDD---EALGNSKALNVIFNGVDKNMFRLI-NTCTVA 97
+ ++ + TT+++ K +++ D E K LN +++ + LI +
Sbjct: 1444 RNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLD 1503
Query: 98 KEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMN----EDESIYEFHMRIRDLANSTFA 153
K +I + T ++ + ++L + + + E+++I E + RD A
Sbjct: 1504 KSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAER--- 1560
Query: 154 LGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEK 213
E +E + R L + FD K+ +E + ++D+L + T + +++ +
Sbjct: 1561 --EAREKETKVLSVSRELDEAFD-KIEDLENKRKTLQNELDDLANTQGTADKNVHELEKA 1617
Query: 214 K----AKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNV 269
K ++ + EE ED + DA + V++ +AL+S + +
Sbjct: 1618 KRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNM--QALRSQFERDLLAKEEGAEEKR 1675
Query: 270 KNTEFQLKD-KHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMY 328
+ QL+D + E D + A+ K + +GD +E+ T ++ E++ +
Sbjct: 1676 RGLVKQLRDLETELDEERKQRTAAVASK-----KKLEGDLKEIETTMEMHNKVKEDALKH 1730
Query: 329 GEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKL 388
+K++ +VKD + + ++ + + +EE++ +SK + K L+ EV L L
Sbjct: 1731 AKKLQAQVKDALRDAEEAK----AAKEELQALSKEADGKVK------ALEAEVLQLTEDL 1780
Query: 389 EGMKKSIRMMNKSTNVLEE 407
+++ R + L E
Sbjct: 1781 ASSERARRAAETERDELAE 1799
Score = 40.8 bits (94), Expect = 0.012
Identities = 60/313 (19%), Positives = 130/313 (41%), Gaps = 35/313 (11%)
Query: 98 KEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESI--YEFHMRIRDLANSTFA-L 154
+E E K A KVR L+ + E +K +S+ +R A L
Sbjct: 1208 QEDLEAEKAARAKAEKVRRD----LSEELEALKNELLDSLDTTAAQQELRSKREQELATL 1263
Query: 155 GEPMSEEKLARK-ILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEK 213
+ + EE + + +L + + ++ +I + + N++ + + L+ + +L +
Sbjct: 1264 KKSLEEETVNHEGVLADMRHKHSQELNSIND--QLENLRKAKTV--LEKAKGTLEAENAD 1319
Query: 214 KAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTE 273
A + V+++ ++ D+R K ++ IAE L + ++ ++
Sbjct: 1320 LATELRSVNSSRQENDRRRKQAESQIAELQVKLAE-------------IERARSELQEKC 1366
Query: 274 FQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMR 333
+L+ + EN T + + K + +S+ E +L E +LL + + K+R
Sbjct: 1367 TKLQQEAENITNQLEEAEL---KASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLR 1423
Query: 334 KEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKK 393
+ + A ++QL+ ++ + + + KL E ++Q K +E+ L EG K+
Sbjct: 1424 QIESEKEALQEQLEEDDEAKRNYER---KLAEVTTQMQEIKKKAEEDADLAKELEEGKKR 1480
Query: 394 SIRMMNKSTNVLE 406
+NK LE
Sbjct: 1481 ----LNKDIEALE 1489
Score = 36.2 bits (82), Expect = 0.29
Identities = 61/318 (19%), Positives = 129/318 (40%), Gaps = 28/318 (8%)
Query: 127 ETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQ 186
+T+ E+++ + ++ + A T L E + +++ R+ ++ + +V ++E
Sbjct: 1097 QTLAEEEEKAKHLAKLKAKHEATIT-ELEERLHKDQQQRQESDRSKRKIETEVADLKEQL 1155
Query: 187 DISNIKVDELIGSLQTFEMSLNGR----SEKKAKSITFVSNTEEDEDQR---EKDTDANI 239
+ ++VDE+ L E L E+ A T E E Q ++D +A
Sbjct: 1156 NERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEK 1215
Query: 240 A---EAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGK 296
A +A + + L + N +LD++ E + K + E T K + +
Sbjct: 1216 AARAKAEKVRRDLSEELEALKN-ELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNH 1274
Query: 297 CYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEE 356
A+ +EL L E +RK L K L++ N+ L E
Sbjct: 1275 EGVLADMRHKHSQELNSINDQL-----------ENLRKAKTVLEKAKGTLEAENADLATE 1323
Query: 357 VKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVG 416
+++++ R+EN++ + + ++ L KL ++++ + + L++ E
Sbjct: 1324 LRSVNSSRQENDR---RRKQAESQIAELQVKLAEIERARSELQEKCTKLQQ--EAENITN 1378
Query: 417 DMEGIGFSYKSANKSASS 434
+E +A KSAS+
Sbjct: 1379 QLEEAELKASAAVKSASN 1396
Score = 32.7 bits (73), Expect = 3.2
Identities = 70/344 (20%), Positives = 133/344 (38%), Gaps = 52/344 (15%)
Query: 54 ELKPEDKWTKKEDDEALGNSKALNVIFNGVDKNMFRLINTCTVAKEAWEILKTAHEGTSK 113
E++ + K ++AL ++K L K+ R AKE + L +G K
Sbjct: 1712 EIETTMEMHNKVKEDALKHAKKLQAQV----KDALRDAEEAKAAKEELQALSKEADGKVK 1767
Query: 114 VRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPK 173
+++ LT + + + E ++AN+ G M +EK R L
Sbjct: 1768 ALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANK-GSLMIDEK------RRLEA 1820
Query: 174 RFDMKVTAIEEAQDISNIKVDELI-GSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQR- 231
R +EE Q S + +D LQ +++ +EK SN++++E+ R
Sbjct: 1821 RIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEK--------SNSQKNENGRA 1872
Query: 232 -----EKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDTTK 286
K+ A +AE + +K+ + + + N E QL+++ + +
Sbjct: 1873 LLERQNKELKAKLAEIETAQRTKVKA--------TIATLEAKIANLEEQLENEGKE---R 1921
Query: 287 AIHVKA--LIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKK 344
+ KA + K + + DE V+ +K + +K+ +K L K+
Sbjct: 1922 LLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQM----------DKLNSRIKLL---KR 1968
Query: 345 QLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKL 388
L LQ+E K + E E + + + E+ L +KL
Sbjct: 1969 NLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKL 2012
Score = 32.7 bits (73), Expect = 3.2
Identities = 70/346 (20%), Positives = 133/346 (38%), Gaps = 33/346 (9%)
Query: 104 LKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLA---NSTFALGEPMS- 159
LK HE T +++L+ + + + D S + + DL N + M
Sbjct: 1112 LKAKHEAT----ITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQA 1167
Query: 160 -----EEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKK 214
EE+L + +LR + + K TA ++AQ ++ E+ L+ E + ++EK
Sbjct: 1168 QLAKREEELTQTLLR-IDEESATKATA-QKAQRELESQLAEIQEDLEA-EKAARAKAEKV 1224
Query: 215 AKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEF 274
+ ++ ++E DT A E S + L +L + L+ + N +
Sbjct: 1225 RRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKS-----LEEETVNHEGVLA 1279
Query: 275 QLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRK 334
++ KH + + K + E + G E L S ++ RK
Sbjct: 1280 DMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRK 1339
Query: 335 EVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKS 394
+ + IAE + L E + S+L+E+ KLQ QE + N E K+
Sbjct: 1340 QAESQIAELQV------KLAEIERARSELQEKCTKLQ------QEAENITNQLEEAELKA 1387
Query: 395 IRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQ 440
+ ++N+ ++ E + + + S + SEK+ Q
Sbjct: 1388 SAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQ 1433
>MYHB_RABIT (P35748) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 53.9 bits (128), Expect = 1e-06
Identities = 83/370 (22%), Positives = 142/370 (37%), Gaps = 50/370 (13%)
Query: 95 TVAKEAWEILKTAHEG-TSKVRMSKLQLLTT------QFETMKMNEDESIYEFHMRIRDL 147
TV K+A + +HE ++R Q++ QF+ K N D++ DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHTQVVEELTEQLEQFKRAKANLDKTKQTLEKENADL 1236
Query: 148 ANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSL 207
A LG+ E + +K L + K + E A+ N KV +L +++ L
Sbjct: 1237 AGELRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERARAELNDKVHKLQNEVESVTGML 1296
Query: 208 N---GRSEKKAKSITFVSNTEEDED---QREKDTDANIAEAVSLLNKALKSLGRM--SNT 259
+ G++ K AK + + + +D Q E N++ + L SL
Sbjct: 1297 SEAEGKAIKLAKEVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEM 1356
Query: 260 NVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKAL---IGKCYSDAESSDGDEEELVETYK 316
N+ ++ QL D + A V++L + + ES EE Y
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVESLEEGKKRFQKEIESLTQQYEEKAAAYD 1416
Query: 317 LL-----------------LAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNS-------- 351
L L + EK +K+ L+AE+K + S +
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEA 1476
Query: 352 -SLQEEVKTISKLR------EENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNV 404
+ ++E K +S R E E+L+ TN L+ E+ L S + + K++ + KS
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1536
Query: 405 LEEILEVGKT 414
LE +E KT
Sbjct: 1537 LETQMEEMKT 1546
Score = 47.8 bits (112), Expect = 9e-05
Identities = 59/275 (21%), Positives = 131/275 (47%), Gaps = 30/275 (10%)
Query: 127 ETMKMNEDESIYEFHM--RIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVT-AIE 183
+T ++ ++E+ + ++ ++R L + +L E + EE A++ L +++++ + +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 184 EAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDA------ 237
+ QD ++ V+ L + F+ + +++ + E+ +++ +++ D
Sbjct: 1379 KLQDFAST-VESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 238 NIAEAVSLLNKALKSLGRM--SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIG 295
N + VS L K K ++ N+ +D E + ++K TKA+ + +
Sbjct: 1438 NQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKE----TKALSLARAL- 1492
Query: 296 KCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQE 355
E + +EEL T K+L A+ E+ + + K V +L K+ L++ E
Sbjct: 1493 ------EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ----ME 1542
Query: 356 EVKTISKLREENEKLQIT-NAKLQEEVTLLNSKLE 389
E+KT +L E ++LQ T +AKL+ EV + K++
Sbjct: 1543 EMKT--QLEELEDELQATEDAKLRLEVNMQALKVQ 1575
Score = 42.4 bits (98), Expect = 0.004
Identities = 56/297 (18%), Positives = 118/297 (38%), Gaps = 42/297 (14%)
Query: 102 EILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEE 161
EI TA E K + + L M++ ED + E + DL A E ++
Sbjct: 1670 EIFATAKENEKKAKSLEADL-------MQLQEDLAAAERARKQADLEKEELA--EELASS 1720
Query: 162 KLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFV 221
R L+ +R + ++ +EE +++E G+++ + ++ ++A+ ++
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEE-------ELEEEQGNMEAMSDRVR-KATQQAEQLSNE 1772
Query: 222 SNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHE 281
TE Q+ + + NK LKS ++ E +K K +
Sbjct: 1773 LATERSTAQKNESARQQLERQ----NKELKS---------------KLQEMEGAVKSKFK 1813
Query: 282 NDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIA 341
+ T A+ K I + E +++ + K K +E + E RK +
Sbjct: 1814 S-TIAALEAK--IAQLEEQVEQEAREKQAAAKALKQRDKKLKEMLLQVEDERKMAEQY-- 1868
Query: 342 EKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMM 398
K+Q + N+ +++ + + + EE++++ KLQ E+ E M + + +
Sbjct: 1869 -KEQAEKGNAKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 34.7 bits (78), Expect = 0.83
Identities = 61/305 (20%), Positives = 131/305 (42%), Gaps = 48/305 (15%)
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEE---AQDISNIKVDELIGSL 200
+ DL +S +G+ + E + +++ L + + ++ +E+ A + + ++++ + +L
Sbjct: 1513 MEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQAL 1572
Query: 201 QT-FEMSLNGR---SEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSL--- 253
+ FE L R +E+K + + + E E + E+ A A A L LK L
Sbjct: 1573 KVQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 254 ------GRMSNTNVLDNVSDNVKNTEFQLKDKH----------ENDTTKAIHVKALIGKC 297
GR L + +K+ + +L+D + + KA ++A + +
Sbjct: 1633 ADSAIKGREEAIKQLLKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 298 YSDA-------ESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVK--DLIAEKKQLQS 348
D + +D ++EEL E L+ + + EK R E + L E ++ Q
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSG--RNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 349 NNSSLQEEVKTISKLREE-----------NEKLQITNAKLQEEVTLLNSKLEGMKKSIRM 397
N ++ + V+ ++ E+ +K + +L+ + L SKL+ M+ +++
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELKSKLQEMEGAVKS 1810
Query: 398 MNKST 402
KST
Sbjct: 1811 KFKST 1815
Score = 32.7 bits (73), Expect = 3.2
Identities = 27/105 (25%), Positives = 54/105 (50%), Gaps = 8/105 (7%)
Query: 308 EEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREEN 367
++EL E + A+ EE G++++ E K + + L+ L+EE KL+ E
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ---LEEEEAARQKLQLEK 973
Query: 368 EKLQITNAKLQEEVTLL---NSKLEGMKKSI--RMMNKSTNVLEE 407
+ KL++++ ++ N+KL +K + R+ + +TN+ EE
Sbjct: 974 VTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Score = 32.0 bits (71), Expect = 5.4
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 19/169 (11%)
Query: 288 IHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQ 347
+ +A I K D D +L + KLL + + + ++ K+L K + +
Sbjct: 974 VTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 348 SNNSSLQEEVKTISKLREENEKL-------------QITN--AKLQEEVTLLNSKLEGMK 392
S S L+ +K K R+E EKL QI + A++ E L K E ++
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 393 KSIRMMNKST----NVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQ 437
++ + T N L++I E+ + D++ S ++A A +K+
Sbjct: 1094 AALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1142
>CAG5_HUMAN (O15320) CTAGE family member 5 (Meningioma-expressed
antigen 6/11) (MEA6/MEA11)
Length = 804
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/294 (21%), Positives = 134/294 (44%), Gaps = 23/294 (7%)
Query: 133 EDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIK 192
+DE + + RI+ L + + +L ++E K+ +I +R + AI++A + ++
Sbjct: 162 QDELMADISKRIQSLEDESKSLKSQVAEAKMTFQIFPMNEERLKI---AIKDALNENSQL 218
Query: 193 VDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKS 252
+ LQ E+ SE + +TF +++ +Q D +++I L K +K
Sbjct: 219 QESQKQLLQEAEVWKEQVSELNKQKVTF-EDSKVHAEQVLNDKESHIKTLTERLLK-MKD 276
Query: 253 LGRMSNTNVLDNVSDNVKNTEFQLKDKHEN----DTTKAIHVKALI--GKCYSDAESSDG 306
M ++ D+ N E ++ + EN D +K LI K + ++ +G
Sbjct: 277 WAAMLGEDITDD-----DNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEG 331
Query: 307 DEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREE 366
+ ++ + EE + + ++ E L +E ++ N LQ+++K +++L +E
Sbjct: 332 ERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQE 391
Query: 367 NEKLQITNAKLQEEVTL-LNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDME 419
NE KL ++T+ N +LE +K ++ K ++ EE+ K D+E
Sbjct: 392 NE------MKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE 439
>MYHB_MOUSE (O08638) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 52.8 bits (125), Expect = 3e-06
Identities = 84/370 (22%), Positives = 142/370 (37%), Gaps = 50/370 (13%)
Query: 95 TVAKEAWEILKTAHEG-TSKVRMSKLQLLTT------QFETMKMNEDESIYEFHMRIRDL 147
TV K+A + +HE ++R Q + QF+ K N D+S DL
Sbjct: 1177 TVLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADL 1236
Query: 148 ANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSL 207
A LG+ E + +K L + K + E A+ + KV +L +++ L
Sbjct: 1237 AGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGML 1296
Query: 208 N---GRSEKKAKSITFVSNTEEDED---QREKDTDANIAEAVSLLNKALKSLGRM--SNT 259
N G++ K AK + + + +D Q E N++ + L SL
Sbjct: 1297 NEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEM 1356
Query: 260 NVLDNVSDNVKNTEFQLKD--KHENDTTKAIHV---------KALIG---------KCYS 299
N+ +V QL D K D I V K + G Y
Sbjct: 1357 EAKQNLERHVSTLNIQLSDSKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYD 1416
Query: 300 DAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNS-------- 351
E + ++ ++ + L + EK +K+ L+AE+K + S +
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEA 1476
Query: 352 -SLQEEVKTISKLR------EENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNV 404
+ ++E K +S R E E+L+ TN L+ E+ L S + + K++ + KS
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 1536
Query: 405 LEEILEVGKT 414
LE +E KT
Sbjct: 1537 LETQMEEMKT 1546
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/269 (24%), Positives = 129/269 (47%), Gaps = 30/269 (11%)
Query: 127 ETMKMNEDESIYEFHM--RIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVT-AIE 183
+T ++ ++E+ + ++ ++R L + +L + + EE A++ L +++++ + +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKK 1378
Query: 184 EAQDI-SNIKV-DELIGSLQTFEMSLNGRSEKKAKSITFVSNT----EEDEDQREKDTDA 237
+ QD S I+V +E LQ L+ + E+KA + + T +++ D D D
Sbjct: 1379 KLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD- 1437
Query: 238 NIAEAVSLLNKALKSLGRM--SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIG 295
N + VS L K K ++ N+ +D E + ++K TKA+ + +
Sbjct: 1438 NQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKE----TKALSLARAL- 1492
Query: 296 KCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQE 355
E + +EEL T K+L A+ E+ + + K V +L K+ L++ E
Sbjct: 1493 ------EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ----ME 1542
Query: 356 EVKTISKLREENEKLQIT-NAKLQEEVTL 383
E+KT +L E + +Q T +AKL+ EV +
Sbjct: 1543 EMKT--QLEESEDDVQATEDAKLRLEVNM 1569
Score = 44.7 bits (104), Expect = 8e-04
Identities = 88/403 (21%), Positives = 156/403 (37%), Gaps = 77/403 (19%)
Query: 104 LKTAHEGTS---KVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMS- 159
LK+ HE +VR+ K + + E +K + +FH +I DL L ++
Sbjct: 1028 LKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 160 -EEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSI 218
EE+L + R L + K A+++ +++ + +L L + E + ++EK+ + +
Sbjct: 1088 KEEELQAALAR-LDEEIAQKNNALKKIRELEG-HISDLQEDLDS-ERAARNKAEKQKRDL 1144
Query: 219 -----TFVSNTEE--DEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKN 271
+ E+ D +++ A + V++L KAL R V + + +
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQA 1204
Query: 272 TEFQLKDKHENDTTKAIHVKALIGKCYSDAESSD--------GDEEELVETYK----LLL 319
E + + KA K+ K + E++D G ++ VE K + L
Sbjct: 1205 VEELTEQLEQFKRAKANLDKS---KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQL 1261
Query: 320 AKWEESCMYGEKMRKEVKDLI----------------AEKK-------------QLQSNN 350
+ C GE+ R E+ D + AE K QLQ
Sbjct: 1262 QDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQ 1321
Query: 351 SSLQEEVK-------TISKLREENEKLQ-------ITNAKLQEEVTLLNSKLEGMKKSIR 396
LQEE + + +L +E LQ L+ V+ LN +L KK ++
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKKKLQ 1381
Query: 397 MMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTK 439
+ V+EE GK E G S + K+A+ +K K
Sbjct: 1382 DFASTIEVMEE----GKKRLQKEMEGLSQQYEEKAAAYDKLEK 1420
Score = 36.6 bits (83), Expect = 0.22
Identities = 53/297 (17%), Positives = 110/297 (36%), Gaps = 42/297 (14%)
Query: 102 EILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEE 161
EI T+ E K + + L M++ ED + E + DL A E ++
Sbjct: 1670 EIFATSKENEKKAKSLEADL-------MQLQEDLAAAERARKQADLEKEELA--EELASS 1720
Query: 162 KLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFV 221
R L+ +R + ++ +EE + ++ + ++ + S + A +
Sbjct: 1721 LSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTA 1780
Query: 222 SNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHE 281
E Q E+ NK L+S ++ E +K K +
Sbjct: 1781 QKNESARQQLERQ------------NKELRS---------------KLQEVEGAVKAKLK 1813
Query: 282 NDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIA 341
+ T A+ K I + E +++ ++ K K +E + E RK +
Sbjct: 1814 S-TVAALEAK--IAQLEEQVEQEAREKQAATKSLKQKDKKLKEVLLQVEDERKMAEQY-- 1868
Query: 342 EKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMM 398
K+Q + N+ +++ + + + EE++ + KLQ E+ E M + + +
Sbjct: 1869 -KEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 33.9 bits (76), Expect = 1.4
Identities = 36/162 (22%), Positives = 74/162 (45%), Gaps = 20/162 (12%)
Query: 262 LDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAK 321
+ +++ + E +LK+ + T A L + ++ E EE V L AK
Sbjct: 861 MQKITERQQKAETELKELEQKHTQLAEEKTLLQEQLQAETELYAESEEMRVR----LAAK 916
Query: 322 WEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENE----KLQITNA-- 375
+E +M +++ ++QLQ+ + +++ + + EE E KLQ+
Sbjct: 917 KQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 376 -----KLQEEVTLL---NSKLEGMKKSI--RMMNKSTNVLEE 407
KL++++ ++ NSKL +K + R+ + +TN+ EE
Sbjct: 977 EAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNLAEE 1018
Score = 31.6 bits (70), Expect = 7.0
Identities = 59/306 (19%), Positives = 132/306 (42%), Gaps = 50/306 (16%)
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDI------SNIKVDELI 197
+ DL +S +G+ + E K R+L + + T +EE++D + ++++ +
Sbjct: 1513 MEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEESEDDVQATEDAKLRLEVNM 1569
Query: 198 GSLQ-TFEMSLNGR---SEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSL 253
+L+ FE L R +E+K + + + E E + E+ A A A L LK L
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 254 GRMSNTNVL--DNVSDNVKNTEFQLKD-KHENDTTKAIH--VKALIGKCYSDAESSDGDE 308
+++ + + ++ + Q+KD + E D +A + A + A+S + D
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEADL 1689
Query: 309 EELVETYKLLLAKWEESCMYGEKMRKEVKDLIA-------EKKQLQSNNSSLQEEVKT-- 359
+L E +++ + E++ +E+ ++ EK++L++ + L+EE++
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQ 1749
Query: 360 -----------------------ISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIR 396
++ R +K + +L+ + L SKL+ ++ +++
Sbjct: 1750 GNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLQEVEGAVK 1809
Query: 397 MMNKST 402
KST
Sbjct: 1810 AKLKST 1815
Score = 31.6 bits (70), Expect = 7.0
Identities = 20/73 (27%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 320 AKWEESCMYGEKMRK---EVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAK 376
AK EE E+ +K E+K+L + QL + LQE+++ ++L E+E++++ A
Sbjct: 856 AKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQLQAETELYAESEEMRVRLAA 915
Query: 377 LQEEVTLLNSKLE 389
++E+ + ++E
Sbjct: 916 KKQELEEILHEME 928
Score = 31.2 bits (69), Expect = 9.2
Identities = 38/169 (22%), Positives = 73/169 (42%), Gaps = 19/169 (11%)
Query: 288 IHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQ 347
+ +A I K D D +L + KLL + + + ++ K+L K + +
Sbjct: 974 VTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHE 1033
Query: 348 SNNSSLQEEVKTISKLREENEKL-------------QITN--AKLQEEVTLLNSKLEGMK 392
S S L+ +K K R+E EKL QI + A++ E L K E ++
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 393 KSIRMMN----KSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQ 437
++ ++ + N L++I E+ + D++ S ++A A +K+
Sbjct: 1094 AALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR 1142
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 50.8 bits (120), Expect = 1e-05
Identities = 66/332 (19%), Positives = 134/332 (39%), Gaps = 32/332 (9%)
Query: 104 LKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSE--- 160
+K+ E S ++ S++ L Q + +K + + I+ + + T + E E
Sbjct: 1210 MKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNF 1269
Query: 161 -EKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEM------SLNGRSEK 213
EK ++ L D +E ++ IK +EL ++ +L+ EK
Sbjct: 1270 KEKEVSELEDKLKASEDKNSKYLELQKESEKIK-EELDAKTTELKIQLEKITNLSKAKEK 1328
Query: 214 KAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSN---TNVLDNVSDNVK 270
++ + T +E + ++ + + + N+A + ++ N + + S+ +
Sbjct: 1329 SESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKIN 1388
Query: 271 NTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGE 330
E +L + KA + + + S+D EE T K L +E Y +
Sbjct: 1389 TLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQ---DEILSYKD 1445
Query: 331 KM-----------RKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQE 379
K+ R +DL + K+QL++ S + + + KL EE+ K + K +E
Sbjct: 1446 KITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKE 1505
Query: 380 EVTLLNSKLEG----MKKSIRMMNKSTNVLEE 407
+ L S +E +K S+ + KS LE+
Sbjct: 1506 MMKKLESTIESNETELKSSMETIRKSDEKLEQ 1537
Score = 42.4 bits (98), Expect = 0.004
Identities = 68/354 (19%), Positives = 142/354 (39%), Gaps = 35/354 (9%)
Query: 53 TELKPEDKWTKKEDDEALGNSKALNVIFNGVDKNMFRLIN--TCTVAKEAWEILKTAHE- 109
+ LK +K +E L K I N + +L+N + T+ +E E + T +
Sbjct: 1334 SRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDE 1393
Query: 110 -----GTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMS--EEK 162
++++ ++ ++ E + ++ DE + E I+ L + + + ++ +EK
Sbjct: 1394 LIRLQNENELKAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEK 1453
Query: 163 LARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVS 222
L I R + + + AQ+ S KV+E + L+ EK + + +
Sbjct: 1454 LL-SIERDNKRDLESLKEQLRAAQE-SKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLE 1511
Query: 223 NTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHEN 282
+T E + K + I ++ L ++ KS +++KN + + D
Sbjct: 1512 STIESNETELKSSMETIRKSDEKLEQSKKS------------AEEDIKNLQHEKSDLISR 1559
Query: 283 DTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAE 342
++ L K +A+S G E E V+ +E EK+R ++
Sbjct: 1560 INESEKDIEELKSKLRIEAKS--GSELETVK---------QELNNAQEKIRINAEENTVL 1608
Query: 343 KKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIR 396
K +L+ L+++ I +EE E L +L++E+ K + ++ R
Sbjct: 1609 KSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERR 1662
Score = 41.2 bits (95), Expect = 0.009
Identities = 66/285 (23%), Positives = 117/285 (40%), Gaps = 31/285 (10%)
Query: 112 SKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSL 171
SK M KL+ ET + E+I + ++ S + + EK L
Sbjct: 1503 SKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEK------SDL 1556
Query: 172 PKRFDMKVTAIEEAQDISNIKVDELIGS-LQTFEMSLNGRSEK---KAKSITFVSNTEED 227
R + IEE + S ++++ GS L+T + LN EK A+ T + + ED
Sbjct: 1557 ISRINESEKDIEELK--SKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLED 1614
Query: 228 EDQREKDTDANIA---EAVSLLNKALKSLGR-MSNTNVLDNVSDNVKNTE---FQLKDKH 280
++ KD A I E LL LK L + + +T S+ + E FQ++
Sbjct: 1615 IERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQ 1674
Query: 281 ENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLI 340
++ + K Y+D + + + +T K + EK+ KE+ +L
Sbjct: 1675 LDEKAMLLETK------YNDLVNKEQAWKRDEDTVKKTTDSQRQEI---EKLAKELDNLK 1725
Query: 341 AEKKQLQSNN---SSLQEEVKTISKLREENEKLQITNAKLQEEVT 382
AE +L+ N S + + + ++ L E+N K + L E++
Sbjct: 1726 AENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEIS 1770
Score = 38.1 bits (87), Expect = 0.075
Identities = 86/468 (18%), Positives = 180/468 (38%), Gaps = 59/468 (12%)
Query: 83 VDKNMFRLINTCTVAKEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHM 142
++KN+ +L T + ++ E + + + + S++ LL + ET DE++
Sbjct: 1020 IEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVN---- 1075
Query: 143 RIRDLANSTFALGEPMSEEKLARKILRS-LPKRFDMKVTAIEEAQDISNIKVDELIGSLQ 201
+I +L + E + E A K L++ L + + A++E ++ +E I L+
Sbjct: 1076 KISELTKTR----EELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKI-QLE 1130
Query: 202 TFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNV 261
+ ++ + ED + K + IA N+ + L +
Sbjct: 1131 KEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQ 1190
Query: 262 LDNVSDNVKNTEFQLKDK------HENDTTKAIHVKALIGKCYSDAESSDGDEEELVETY 315
+N S KN E + + K E K + AL + + ++ +E L+E+
Sbjct: 1191 QENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESI 1250
Query: 316 KLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNA 375
K V+ + K+LQ + ++EV + + +E
Sbjct: 1251 K------------------SVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYL 1292
Query: 376 KLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSE 435
+LQ+E + +L+ +++ LE+I + K E S S K SSE
Sbjct: 1293 ELQKESEKIKEELDAKTTELKIQ------LEKITNLSKAKEKSE----SELSRLKKTSSE 1342
Query: 436 KQTKQPMSDPMLHHSVRHVYPQFRKSKK------STWRCHHCGKLGHIRPYCYKLYGYPQ 489
++ L + ++ F K +K ST + K+ + +L Q
Sbjct: 1343 ERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRL----Q 1398
Query: 490 SHDQPRTNPQVAPTRKEWKPSGLKE----KEKKEIVKAPRHFLMTNKD 533
+ ++ + ++ TR E + L +EK+ +K+ + +++ KD
Sbjct: 1399 NENELKAK-EIDNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKD 1445
Score = 35.8 bits (81), Expect = 0.37
Identities = 71/372 (19%), Positives = 156/372 (41%), Gaps = 58/372 (15%)
Query: 85 KNMFRLINTCTVAKEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIY-EFHMR 143
+ + L N E ++IL ++H + +L T+ + ++ + DE +
Sbjct: 762 EKLIALTNEHKELDEKYQILNSSHSSLKE----NFSILETELKNVRDSLDEMTQLRDVLE 817
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQD-ISNIKVDELIGSLQT 202
+D N T AL E S +++L K + ++ ++A+D I+ + D S +
Sbjct: 818 TKDKENQT-ALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREM 876
Query: 203 FEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVL 262
+ N ++ +K K + V++ +E + +E D A I E + +N+ L+ + N L
Sbjct: 877 QAVEENCKNLQKEKDKSNVNHQKETKSLKE-DIAAKITE-IKAINENLEEMKIQCNN--L 932
Query: 263 DNVSDNVKNTEFQLKDK---HENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKL-- 317
+++ + K + H+N K + Y D ++ + + VE K
Sbjct: 933 SKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNES 992
Query: 318 ------------LLAKWEESCMYG--------EKMRKEVKDLIAEKKQLQSNNSS----- 352
+++ +E+ E+++K + DL K+++ S + S
Sbjct: 993 SIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEY 1052
Query: 353 ------LQEEVKTISKLREEN----EKLQITNAKLQEEVTL-------LNSKLEGMKKSI 395
L+E+++T + +EN +L T +L+ E+ L +KLE +K++
Sbjct: 1053 ESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKAL 1112
Query: 396 RMMNKSTNVLEE 407
+ + ++ L+E
Sbjct: 1113 KEVKENEEHLKE 1124
>RA50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase
Length = 879
Score = 50.8 bits (120), Expect = 1e-05
Identities = 64/287 (22%), Positives = 138/287 (47%), Gaps = 36/287 (12%)
Query: 143 RIRDLANSTFALGEPMSEEKLARKI--LRSLPK-RFDMKVTAIEEAQDISNIKVDELIGS 199
+I L +S + E M +K+ KI L+SL K + + + I++ +++ NIK +
Sbjct: 161 KIEKLRDSNGPIKEVM--DKINNKIIELQSLEKYKNESENQKIQKEKELENIKREL---- 214
Query: 200 LQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNT 259
LN + EK+ K + E+E+++EK E +SLLNK + +
Sbjct: 215 -----EDLNIKEEKERKKYEDIVKLNEEEEKKEK----RYVELISLLNKLKDDISELR-- 263
Query: 260 NVLDNVSDNVKNTEFQLKDKHEND---TTKAIHVKALIGKCYSDAESSDGDEEELVETYK 316
+ V D +N + K+K E D K I K I + + + + ++E+ ++T K
Sbjct: 264 ---EEVKD--ENRLREEKEKLEKDILEKDKLIEEKEKIIEAQNKIKLAQ-EKEKSLKTIK 317
Query: 317 LLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAK 376
+ L EE ++ ++ K I K +L+ L+E+ + + L + + L+I ++
Sbjct: 318 INLTDLEEKLKRKRELEEDYKKYIEIKGELE----ELEEKERKFNSLSDRLKSLKIKLSE 373
Query: 377 LQEEVT--LLNSKLEGMKKSIRMMNKS-TNVLEEILEVGKTVGDMEG 420
++ +++ ++ +E + K ++ +N+ N +E ++ +G+++G
Sbjct: 374 IESKISNRKISINIEELDKELQKLNEDLNNKNQEREKLASQLGEIKG 420
Score = 33.9 bits (76), Expect = 1.4
Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 27/232 (11%)
Query: 224 TEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHEN- 282
+E+ + DT IA + +++ +K L + + + + + +++ EN
Sbjct: 94 SEDTISELTNDTRRTIARGATTVSQKIKELLNLDE----EVLKSTIIVGQGKIESVFENL 149
Query: 283 -DTTKAIHVKALIGKCYSD----AESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVK 337
D TK I I K E D +++E L K E +K++KE K
Sbjct: 150 PDVTKKILKIDKIEKLRDSNGPIKEVMDKINNKIIELQSLEKYKNESE---NQKIQKE-K 205
Query: 338 DLIAEKKQLQSNNSSLQEEVKT---ISKLREENEKLQITNAKLQEEVTLLN------SKL 388
+L K++L+ N ++E K I KL EE EK + + E ++LLN S+L
Sbjct: 206 ELENIKRELEDLNIKEEKERKKYEDIVKLNEEEEKKE---KRYVELISLLNKLKDDISEL 262
Query: 389 -EGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTK 439
E +K R+ + + ++ILE K + + E I + + EK K
Sbjct: 263 REEVKDENRLREEKEKLEKDILEKDKLIEEKEKIIEAQNKIKLAQEKEKSLK 314
Score = 31.2 bits (69), Expect = 9.2
Identities = 44/210 (20%), Positives = 89/210 (41%), Gaps = 26/210 (12%)
Query: 213 KKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNT 272
K + + + TEE + E+ E ++NK + NT++ + D K
Sbjct: 552 KYEEYLKYYDVTEEKIRELERQKIELEKEIEEIMNKVREYY----NTDLTQKIRDIEKRI 607
Query: 273 EFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVE-TYKLLLAKWEESCMYGEK 331
+ ++K K K + L+ K + + +EEE+ + T +L L ++ + K
Sbjct: 608 Q-EIKGKEN----KLRELDTLLAKIETAKQKIKQNEEEIKKLTDELQLLNFDPNRFQQIK 662
Query: 332 MRKEVKD------------LIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQE 379
KEV + L+ +K+ L+++ L+E++K + + +KL KL++
Sbjct: 663 REKEVLEKILGEINSKKGELLGKKEVLENDIKRLEEQIKDYEEKLKNKQKLITAYDKLKK 722
Query: 380 EVTLLNSKLEGMKKSIRMMNKSTNVLEEIL 409
L L K +MN +++E+ L
Sbjct: 723 ----LREHLAEDKLQAYLMNTVKSLVEDSL 748
>RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase
Length = 864
Score = 50.8 bits (120), Expect = 1e-05
Identities = 77/368 (20%), Positives = 156/368 (41%), Gaps = 59/368 (16%)
Query: 104 LKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKL 163
+K + K R L+L TT +K+ E E + E + I +L T + + + +E
Sbjct: 223 IKDQFDEYEKKRNQYLKLTTT----LKIKEGE-LNELNRSIEELRKQTENMDQ-LEKEIN 276
Query: 164 ARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSN 223
+ LR++ +F+ K + ++ + V L ++ +E ++ + E + K + +
Sbjct: 277 ELENLRNIKLKFE-KYEVLAKSHTEMSANVINLEKEIEEYEKAIRRKEELEPKYLKYKEL 335
Query: 224 TEEDEDQREK-----DTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKD 278
+ E+ + K +++ ++L + K +SN +D V+ L+
Sbjct: 336 ERKLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSND--IDKVNS--------LEQ 385
Query: 279 KHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESC------MYGEKM 332
K E K ++++A + K ES ++ E++ + + C + +K+
Sbjct: 386 KVEETRKKQLNLRAQLAK----VESLISEKNEIINNISQVEGETCPVCGRPLDEEHKQKI 441
Query: 333 RKEVKDLIAEKKQLQSNNSSLQEEVKTI----SKLREENEKLQITNA----------KLQ 378
KE K I QL+ N + L+EE+K I +K+ E +L A KL
Sbjct: 442 IKEAKSYIL---QLELNKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLN 498
Query: 379 EEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQT 438
EE+ L+S++E +K N+ EEI ++ + V +++ + +K E
Sbjct: 499 EEIENLHSEIESLK----------NIDEEIKKINEEVKELKLYYEEFMRLSKYTKEELDK 548
Query: 439 KQPMSDPM 446
K+ D M
Sbjct: 549 KRVKLDEM 556
Score = 39.3 bits (90), Expect = 0.034
Identities = 57/329 (17%), Positives = 138/329 (41%), Gaps = 34/329 (10%)
Query: 130 KMNEDESIYEFHMRIRDLANSTFALGEPMSEE------------KLARKILRSLPKRFDM 177
K+ E + Y+ +++++ +S L E + ++ L +K+ + K+ ++
Sbjct: 338 KLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSNDIDKVNSLEQKVEETRKKQLNL 397
Query: 178 KVTAIEEAQDISNIKVDELIGSLQTFE---MSLNGR---SEKKAKSITFVSNTEEDEDQR 231
+ + IS + +E+I ++ E + GR E K K I + +
Sbjct: 398 RAQLAKVESLIS--EKNEIINNISQVEGETCPVCGRPLDEEHKQKIIKEAKSYILQLELN 455
Query: 232 EKDTDANIAEAVSLLNKALKSLGRMSNTNV-LDNVSDNVKNTEFQLKDKHENDTTKAIHV 290
+ + + + + + LNK + R+SN DNV +K ++++ H ++ ++
Sbjct: 456 KNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLNEEIENLH-SEIESLKNI 514
Query: 291 KALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNN 350
I K + + EE + K + ++ + ++M+K+ +++ E + L+S
Sbjct: 515 DEEIKKINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDEMKKKKEEIEKEMRGLESEL 574
Query: 351 SSLQEEVKTISKLREENEKLQITNAKLQE--------EVTLLNSKLEGMKKSIRMMNKST 402
L + L EN+++++ K ++ +V LL +++ +++ + ++
Sbjct: 575 KGLDRKALESKILDLENKRVKLDEMKKKKGILEDYIRQVKLLQEEVKNLREEVNIIQFDE 634
Query: 403 NVLEEILEVGKTVGDMEGIGFSYKSANKS 431
N E+ KT D + K KS
Sbjct: 635 NRYNEL----KTSLDAYNLSLKEKENRKS 659
>PCP1_SCHPO (Q92351) Spindle pole body protein pcp1
Length = 1208
Score = 50.8 bits (120), Expect = 1e-05
Identities = 69/329 (20%), Positives = 131/329 (38%), Gaps = 62/329 (18%)
Query: 118 KLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDM 177
+LQ +T + ET++M + E H DL E L KI S+ K D
Sbjct: 500 RLQEVTKELETLRMKNSNDLNEIH----DLREEN---------EGLTLKI-DSITKEKDR 545
Query: 178 KVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDE--------- 228
+ +E+ + V EL G++ + L + E + + + D
Sbjct: 546 LINELEQRIKSYEVNVSELNGTIDEYRNKLKDKEETYNEVMNAFQYKDNDLRRFHESINK 605
Query: 229 -DQREKDTDANIA----------EAVSLLNKALKSLGR--------MSNTNVLDNVSDNV 269
REK+ +N+ E V++L K +S+ + + NTN+++ ++D +
Sbjct: 606 LQDREKELTSNLEKKNLVISSLRETVAMLEKERESIKKYLSGNAKDLDNTNLMEILNDKI 665
Query: 270 KNTEFQLKD-KHENDTTKAIHVKALIG--KCYSDAESSDGDEE-----------ELVETY 315
+ QL D K E D ++ +A++ K + E +++ EL+
Sbjct: 666 SVLQRQLTDVKDELDVSEEEREEAIVAGQKLSASFELMSNEKQALELKYSSLKNELINAQ 725
Query: 316 KLLLAKWEESCMYGEKMRKEVK------DLIAEKKQLQSNNSSLQEEVKTISKLREENEK 369
LL + EE +K+ +E K D I + K++ NS L +++ I L + +
Sbjct: 726 NLLDRREEELSELSKKLFEERKIRSGSNDDIEKNKEINVLNSELADKLAQIRHLESDKME 785
Query: 370 LQITNAKLQEEVTLLNSKLEGMKKSIRMM 398
L L + N + +KK + ++
Sbjct: 786 LDKLVHHLNRGIEEANIEENAVKKRLCLL 814
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/370 (20%), Positives = 159/370 (42%), Gaps = 73/370 (19%)
Query: 84 DKNMFRLINTCTVAKEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMR 143
D N RL+ T ++ + E L+T + + + + L+LL ++ N D+++ E ++R
Sbjct: 450 DNNSLRLM-TSSLGNQI-ESLRTQNREIDEEK-NHLRLLASK------NSDKALAETNIR 500
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTF 203
++++ L S + LR + +K+ +I + +D ++++ I S +
Sbjct: 501 LQEVTKELETLRMKNSNDLNEIHDLREENEGLTLKIDSITKEKDRLINELEQRIKSYEVN 560
Query: 204 EMSLNG-----RSEKKAKSITF--VSNTEEDED--------------QREKDTDAN---- 238
LNG R++ K K T+ V N + +D REK+ +N
Sbjct: 561 VSELNGTIDEYRNKLKDKEETYNEVMNAFQYKDNDLRRFHESINKLQDREKELTSNLEKK 620
Query: 239 ------IAEAVSLLNKALKSLGR--------MSNTNVLDNVSDNVKNTEFQLKDKHENDT 284
+ E V++L K +S+ + + NTN+++ ++D + + QL D +
Sbjct: 621 NLVISSLRETVAMLEKERESIKKYLSGNAKDLDNTNLMEILNDKISVLQRQLTDVKD--- 677
Query: 285 TKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKK 344
+ + S+ + EE + + L A +E M EK E+K + +
Sbjct: 678 ---------------ELDVSEEEREEAIVAGQKLSASFE--LMSNEKQALELKYSSLKNE 720
Query: 345 QLQSNN--SSLQEEVKTISKLREENEKLQI---TNAKLQEEVTLLNSKLEGMKKSIRMMN 399
+ + N +EE+ +SK E K++ + + +E+ +LNS+L IR +
Sbjct: 721 LINAQNLLDRREEELSELSKKLFEERKIRSGSNDDIEKNKEINVLNSELADKLAQIRHLE 780
Query: 400 KSTNVLEEIL 409
L++++
Sbjct: 781 SDKMELDKLV 790
Score = 35.8 bits (81), Expect = 0.37
Identities = 59/294 (20%), Positives = 120/294 (40%), Gaps = 54/294 (18%)
Query: 143 RIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQD-ISNIKVDELIGSLQ 201
+I++ L + +L K SL ++ + K +EE D +S + E +++
Sbjct: 186 QIKEAVKDNVELHAERANLQLQLKRTESLLQKSEDKNFKLEEKVDYLSKVNDVEQSQNVK 245
Query: 202 TFEMSL----NGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMS 257
F + N + + + + + EED+ +E D + I + + L++ + L
Sbjct: 246 VFTERIRFLENALEKVQREKDSLSTEMEEDKSNKEVDYEYEIRQLQNRLDELSEELDVAQ 305
Query: 258 NTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKL 317
+ +L D + + Q+++K + + + + E+S L E Y +
Sbjct: 306 D--LLTEKEDEIATLKRQIEEKENSSSA------------FENEENSS--YVHLQEDYAI 349
Query: 318 LLAKWEESCMYGEKMRKEVKDLIAEKKQ--------------------LQSNNSSLQEEV 357
L AK +E + ++++ DL EK+ LQ EE+
Sbjct: 350 LQAKCDE---FADRIQVLTADLEKEKENQIMHESEASIGLTDSMQVHTLQEQLHKANEEI 406
Query: 358 K----TISKLREEN---EKLQITNAKLQEEVTLLNSKLEGMK---KSIRMMNKS 401
+ IS++ EE E + + L+EE +L SKL+ ++ S+R+M S
Sbjct: 407 EFLHDQISRMNEEGKNFEDIMLQFRSLEEERDVLESKLQTLEDDNNSLRLMTSS 460
Score = 33.9 bits (76), Expect = 1.4
Identities = 66/320 (20%), Positives = 132/320 (40%), Gaps = 39/320 (12%)
Query: 102 EILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEE 161
E ++ KV+ K L+T+ E K N++ ++ IR L N L E +
Sbjct: 249 ERIRFLENALEKVQREK-DSLSTEMEEDKSNKE---VDYEYEIRQLQNRLDELSEELD-- 302
Query: 162 KLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGS---LQTFEMSLNGRSEKKAKSI 218
+A+ +L IEE ++ S+ +E S LQ L + ++ A I
Sbjct: 303 -VAQDLLTEKEDEIATLKRQIEEKENSSSAFENEENSSYVHLQEDYAILQAKCDEFADRI 361
Query: 219 TFVSNT--EEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNV------LDNVSDNVK 270
++ +E E+Q +++A+I S+ L+ +N + + +++ K
Sbjct: 362 QVLTADLEKEKENQIMHESEASIGLTDSMQVHTLQEQLHKANEEIEFLHDQISRMNEEGK 421
Query: 271 NTE-----FQLKDKH-----------ENDTTKAIHVKALIGKCYSDAESSDGDEEELVET 314
N E F+ ++ E+D + + +G + + + +E
Sbjct: 422 NFEDIMLQFRSLEEERDVLESKLQTLEDDNNSLRLMTSSLGNQIESLRTQNREIDEEKNH 481
Query: 315 YKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITN 374
+LL +K + + +R ++++ E + L+ NS+ ++ I LREENE L +
Sbjct: 482 LRLLASKNSDKALAETNIR--LQEVTKELETLRMKNSN---DLNEIHDLREENEGLTLKI 536
Query: 375 AKLQEEVTLLNSKLEGMKKS 394
+ +E L ++LE KS
Sbjct: 537 DSITKEKDRLINELEQRIKS 556
>CING_XENLA (Q9PTD7) Cingulin
Length = 1360
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/358 (20%), Positives = 144/358 (39%), Gaps = 46/358 (12%)
Query: 129 MKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDI 188
+K + + + E ++ L+ L E EE + L+ + + ++++ D
Sbjct: 956 VKRDLESKLDEAQRSLKRLSLEYEELQECYQEEMKQKDHLKKTKNELEEQKRLLDKSMDK 1015
Query: 189 SNIKVDELI----GSLQTFEMSLNGRSEKKAKSITFVSNTEED---EDQREKDTDANIAE 241
++D + GSLQ + L EK K I ++ E +R + + + E
Sbjct: 1016 LTRELDNMSNESRGSLQLLQTQLEEYREKSRKEIGEAQKQAKEKTAEAERHQFNSSRMQE 1075
Query: 242 AVSLLNKALKSLGRMSNTNVLDN--VSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYS 299
V L AL+ L T LD +S +++ E ++ K ++ VK L K
Sbjct: 1076 EVQKLKLALQELQVEKETVELDKQMISQRLQSLEQDIESKKRVQDDRSRQVKVLEDKL-- 1133
Query: 300 DAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEV-------KDLIAEKKQLQSNNSS 352
+ + + +E T +LL + S E+ R E+ +DL +K L+ N
Sbjct: 1134 --KRMEAELDEEKNTVELLTDRVNRSRDQMEQQRAELNQERSRGQDLECDKISLERQNKE 1191
Query: 353 LQEEVKTI--------------SKLREENEKLQI----------TNAKLQEEVTLLNSKL 388
L+ + ++ +KL+E E+LQ+ TN KL+ ++ LN +L
Sbjct: 1192 LKNRLASMEGQQKPSVNVSHLEAKLQEIQERLQLEEREKATLLSTNRKLERKLKELNIQL 1251
Query: 389 EGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSEKQTKQPMSDPM 446
E + + N+ + L+ + V + E + K A E + +Q +++ +
Sbjct: 1252 EDERLQVNDQKDQLNLRVKALK--RQVDEAEEEIERLEGLRKKAVREMEEQQEINEQL 1307
Score = 47.0 bits (110), Expect = 2e-04
Identities = 77/362 (21%), Positives = 148/362 (40%), Gaps = 66/362 (18%)
Query: 104 LKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMS---- 159
+K +EG +K ++Q Q K +E++ H R R+L+ AL + +S
Sbjct: 784 VKKENEGLAK-ESRRIQDQLKQVLLEKQRHEETV---HQRERELSVLKGALKDEVSGRDR 839
Query: 160 -EEKLARKI-------------LRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEM 205
EKL ++ L + KR + + T +E + + + E
Sbjct: 840 ETEKLRERLEQDALMTKRSYEELVKINKRLESEKTDLERVRQVIENNLQESREENDDLRR 899
Query: 206 SLNGRSEKKAKSITFVSNTE-------------EDEDQREKDTDANIAEAV--------- 243
+ G + ++ TF + + E E +R +D+ +A+
Sbjct: 900 KILGLEAQLKETNTFCDDLQRAESRLKDKINKLEAERKRMEDSLGEVADQEQELAFVKRD 959
Query: 244 --SLLNKALKSLGRMS--NTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYS 299
S L++A +SL R+S + + + +K + K K+E + K + K++
Sbjct: 960 LESKLDEAQRSLKRLSLEYEELQECYQEEMKQKDHLKKTKNELEEQKRLLDKSMDKL--- 1016
Query: 300 DAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEV-------KDLIAEKKQLQSNNSS 352
D E + +LL + EE Y EK RKE+ K+ AE ++ Q N+S
Sbjct: 1017 -TRELDNMSNESRGSLQLLQTQLEE---YREKSRKEIGEAQKQAKEKTAEAERHQFNSSR 1072
Query: 353 LQEEVK----TISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEI 408
+QEEV+ + +L+ E E +++ + + + L +E K+ ++ VLE+
Sbjct: 1073 MQEEVQKLKLALQELQVEKETVELDKQMISQRLQSLEQDIESKKRVQDDRSRQVKVLEDK 1132
Query: 409 LE 410
L+
Sbjct: 1133 LK 1134
>DYNA_HUMAN (Q14203) Dynactin 1 (150 kDa dynein-associated
polypeptide) (DP-150) (DAP-150) (p150-glued) (p135)
Length = 1278
Score = 50.1 bits (118), Expect = 2e-05
Identities = 57/290 (19%), Positives = 128/290 (43%), Gaps = 54/290 (18%)
Query: 154 LGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEK 213
L P EE+ R +R L ++ ++ ++ A+D + +K L+ ++ L E
Sbjct: 210 LPSPSKEEEGLRAQVRDLEEK--LETLRLKRAEDKAKLK------ELEKHKIQLEQVQEW 261
Query: 214 KAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNT--------NVLDNV 265
K+K + + D +R K+ EA+ + ++ + ++ + +
Sbjct: 262 KSK----MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEER 317
Query: 266 SDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEES 325
+++++ LK++ + TT +KA I + SD +S ++L
Sbjct: 318 AESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL-------------- 363
Query: 326 CMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNA---KLQEEVT 382
E+ +KD + + L S S QE VK + ++N++L++ +LQEE++
Sbjct: 364 ----EEQNARLKDALVRMRDLSS--SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 417
Query: 383 LLNSKLEGMKKSI-----------RMMNKSTNVLEEILEVGKTVGDMEGI 421
S ++ +K+ + + +++ N+ E++ E+ +TVGD+E +
Sbjct: 418 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAM 467
>GCC2_MOUSE (Q8CHG3) GRIP and coiled-coil domain-containing protein
2 (Golgi coiled coil protein GCC185)
Length = 1679
Score = 49.7 bits (117), Expect = 2e-05
Identities = 69/326 (21%), Positives = 141/326 (43%), Gaps = 31/326 (9%)
Query: 98 KEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEP 157
+E EIL+T G S ++S+ +FETMK + ++E ++R N AL E
Sbjct: 479 REMMEILQT-ELGESAGKISQ------EFETMKQQQASDVHELQQKLRSAFNEKDALLET 531
Query: 158 MS-----EEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSE 212
++ EKL + + L + + ++ + + + LQ E ++ ++
Sbjct: 532 VNRLQGENEKLLSQ--QELVPELESTIKNLQADNSMYLASLGQKDTMLQELEAKISSLAK 589
Query: 213 KKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNT 272
+K I+ + + E+ D + + +V L A N+ + VS+
Sbjct: 590 EKDDFISKIKTSHEEMDDLHQKWEREQRLSVELREAA--GQAAQHNSELRQRVSELTGKL 647
Query: 273 EFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKM 332
+ +++K +ND + + +K + D E+ + L E L + E++ + +
Sbjct: 648 DELVREKSQNDQSITVQMKTMT----EDQEALSSKIKSLYEENNRLHS--EKAQLSRDLE 701
Query: 333 RKEVKDLIAEKKQLQSNNSSLQ---EEVKTISKLREENEKLQITNAKLQEEVTLLNSKLE 389
+ + A K+ + LQ EE ++KL ENE++Q + K Q L L+
Sbjct: 702 ALQAQQDFAHKEHVAEFEKKLQLMVEERDDLNKLL-ENEQVQKSFVKTQ-----LYEYLK 755
Query: 390 GMKKSIRMMNKSTNVLEEILEVGKTV 415
++ SI N+ +V++ I VG+++
Sbjct: 756 QLRASILEENEEEDVVKLIQAVGESL 781
Score = 39.7 bits (91), Expect = 0.026
Identities = 72/380 (18%), Positives = 152/380 (39%), Gaps = 62/380 (16%)
Query: 102 EILKTAHEGTS---KVRMSKLQLLTTQFETMKMNEDES---------IYEFHMRIRDLAN 149
++L HE K R S+LQ + + +K + ++S + E +I L
Sbjct: 890 KVLVIEHENLRLLLKQRESELQDVRAELILLKDSLEKSPSVKDQLSLVKELEEKIESLEK 949
Query: 150 STFALGEPMSEEKL-ARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLN 208
+ E +S+ KL A K + L T EE + + + K D L S++ F L
Sbjct: 950 ESKDKDEKISKIKLVAVKAKKELDSNRKEAQTLREELESVRSEK-DRLSASMKEF---LQ 1005
Query: 209 GRSEKKAKSITFVSNTEEDEDQREK--DTDANIAEAVSLLNKALKSLGRMSNTNV----- 261
G K+ + + +E+ + ++E+ + + +I + L + R+++ N
Sbjct: 1006 GAESYKSLLLEYDKQSEQLDVEKERAHNFERHIEDLTKQLRNSTCQYERLTSDNEDLLAR 1065
Query: 262 LDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAK 321
++ + N K E Q+ + V+ G + ++ + +E+ ++ + + +
Sbjct: 1066 IETLQANAKLLEAQI-----------LEVQKAKGVVEKELDAEELQKEQKIKEHVSTVNE 1114
Query: 322 WEESCMYGEKMRKEVKDLIAE----KKQLQSN-----------------NSSLQEEVKTI 360
EE + +K +K+++ + E KK Q N L + TI
Sbjct: 1115 LEELQLQFQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSTI 1174
Query: 361 SKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEG 420
L +E + + LQEE+T L S ++ ++ K+T + + +++ K + D +
Sbjct: 1175 EDLEQEMKIQKEKQETLQEEITSLQSSVQHYEE------KNTKIKQLLVKTKKELADAKQ 1228
Query: 421 IGFSYKSANKSASSEKQTKQ 440
+ S E + Q
Sbjct: 1229 AETDHLLLQASLKGELEASQ 1248
Score = 37.7 bits (86), Expect = 0.098
Identities = 68/326 (20%), Positives = 133/326 (39%), Gaps = 24/326 (7%)
Query: 50 ASTTELKPEDKWTKKEDDEALGNSKALNVIFNGVDKNMFRLINT---CTVAKEAWEILKT 106
A TEL E + K + + G + V+ +D + T C K+ E +K
Sbjct: 45 ARCTELDKEVEELKSKPVDG-GTDDIIKVLTERLDALLLEKAETEQQCLCLKK--ENVKM 101
Query: 107 AHEGTSKVRMSKLQLLTTQFETMKMN---EDESIYEFHMRIRDLANSTFALGEPMSEEKL 163
E V +KL+ +FE N E ES M + + A+ + EE +
Sbjct: 102 KQEVEDSV--TKLEETHKEFEQSHRNYVKEIESCKNELMAVHSEHSKETAILQKELEEAV 159
Query: 164 ARKI--LRSLPKRFDMKVTAIEEAQDISNIKV--DELIGSLQTFEMSLNGRSEKKAKSIT 219
+++ L + D + + ++I NI +E I L E L S++K + I
Sbjct: 160 HKQVELREQLKSQSDSEDNVRKLQEEIQNITAAFEEQISCL---EKKLEATSDEKQQEII 216
Query: 220 FVSNTEEDEDQR-EKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKD 278
+ ED+ Q +KD + AE + L ++ + T ++ + + K E ++
Sbjct: 217 HLQKVIEDKAQHYQKDINTFQAEILQL-----RATHKEEVTELMSQIETSAKEHEAEINK 271
Query: 279 KHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKD 338
EN T+ + + K ++E+ + + + +E + + +V+
Sbjct: 272 LKENRVTQCEASENIPEKYQCESENLNEVASDASPESQNCSVALQEDPSAEQTVCDKVRQ 331
Query: 339 LIAEKKQLQSNNSSLQEEVKTISKLR 364
L K+L+S +S L++EV ++ L+
Sbjct: 332 LEDSLKELESQHSILKDEVTYMNNLK 357
Score = 36.6 bits (83), Expect = 0.22
Identities = 39/194 (20%), Positives = 85/194 (43%), Gaps = 22/194 (11%)
Query: 225 EEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDT 284
+E E+ + K D + + +L + L +L + + +K ++K + E+
Sbjct: 52 KEVEELKSKPVDGGTDDIIKVLTERLDAL--LLEKAETEQQCLCLKKENVKMKQEVEDSV 109
Query: 285 TKAIHVKALIGKCYSDAESSDGDEEELVETYKL-LLAKWEESCMYGEKMRKEVKDLIAEK 343
TK + + + + E S + + +E+ K L+A E ++KE+++ + ++
Sbjct: 110 TK-------LEETHKEFEQSHRNYVKEIESCKNELMAVHSEHSKETAILQKELEEAVHKQ 162
Query: 344 KQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTN 403
+L+ S + + KL+EE +Q A +E+++ L KLE S
Sbjct: 163 VELREQLKSQSDSEDNVRKLQEE---IQNITAAFEEQISCLEKKLEA---------TSDE 210
Query: 404 VLEEILEVGKTVGD 417
+EI+ + K + D
Sbjct: 211 KQQEIIHLQKVIED 224
Score = 35.0 bits (79), Expect = 0.64
Identities = 53/257 (20%), Positives = 108/257 (41%), Gaps = 28/257 (10%)
Query: 176 DMKVTAIEEAQDISNIK--VDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREK 233
+++ A + AQ S ++ V EL G L E+ ++ ++ + TE+ E K
Sbjct: 621 ELREAAGQAAQHNSELRQRVSELTGKLD--ELVREKSQNDQSITVQMKTMTEDQEALSSK 678
Query: 234 -----DTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKH------EN 282
+ + + + L++ L++L + ++V++ K + ++++ EN
Sbjct: 679 IKSLYEENNRLHSEKAQLSRDLEALQAQQDFAHKEHVAEFEKKLQLMVEERDDLNKLLEN 738
Query: 283 DTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAE 342
+ + VK + + +S +E E + KL+ A E E+ V + A
Sbjct: 739 EQVQKSFVKTQLYEYLKQLRASILEENEEEDVVKLIQAVGESLVKVKEEEHNLVFEYDAR 798
Query: 343 KKQLQSNNSSLQ-------EEVKTISKLREENEKL------QITNAKLQEEVTLLNSKLE 389
+L++ LQ EE++T+ + E+ + L +T+AK ++ LL K
Sbjct: 799 VLELENKIKCLQEDSAVQCEELRTLVRDSEQEKILLRKELDAVTSAKEALQLDLLEMKNT 858
Query: 390 GMKKSIRMMNKSTNVLE 406
K S+ ST V E
Sbjct: 859 NEKASLENQTLSTQVEE 875
>MYS2_DICDI (P08799) Myosin II heavy chain, non muscle
Length = 2116
Score = 49.3 bits (116), Expect = 3e-05
Identities = 54/241 (22%), Positives = 105/241 (43%), Gaps = 22/241 (9%)
Query: 212 EKKAKSITFVSNTEEDEDQREK------DTDANIAEAVSLLNKALKSLGRMSNTNVLDNV 265
EK+ + + SN + Q++K DT++N+ + L ++L M ++ D +
Sbjct: 832 EKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSK--DAL 889
Query: 266 SDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKL------LL 319
+ E +++D K + ++ L + S E EEEL E KL L
Sbjct: 890 EAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKLK 949
Query: 320 AKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEK----LQITNA 375
K+EE +++ D I+ +L+ LQ+EV+ +++ E K L+ T
Sbjct: 950 KKYEEELEEMKRVNDGQSDTIS---RLEKIKDELQKEVEELTESFSEESKDKGVLEKTRV 1006
Query: 376 KLQEEVTLLNSKLEG-MKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASS 434
+LQ E+ L +L+ K ++ + + EE+ +V + + + ++ANK
Sbjct: 1007 RLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANKKLQG 1066
Query: 435 E 435
E
Sbjct: 1067 E 1067
Score = 46.2 bits (108), Expect = 3e-04
Identities = 80/381 (20%), Positives = 161/381 (41%), Gaps = 50/381 (13%)
Query: 98 KEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYE---FHMRIRDLANSTFAL 154
+E + L+ + S++ SK +L TT+ E +K D + + + L + L
Sbjct: 1709 EEVRDQLEEEEDSRSELEDSKRRL-TTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTL 1767
Query: 155 GEPMSEEKL-------ARKILRSLPKRFDMKVTAIEEAQDISNIKVD--ELIGSLQTFEM 205
+ + +EK A+K L S + F K+ A E ++ S + D + L+ +
Sbjct: 1768 KKQLEDEKKKLNESERAKKRLESENEDFLAKLDA--EVKNRSRAEKDRKKYEKDLKDTKY 1825
Query: 206 SLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNV 265
LN + K ++ + E+ D+ + A+A +K+ K+L +DN+
Sbjct: 1826 KLNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQA-DKSKKTL-----EGEIDNL 1879
Query: 266 SDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEES 325
+++ E ++K + E + + + +AE S + E+ +L L
Sbjct: 1880 RAQIED-EGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELEL------ 1932
Query: 326 CMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNA-----KLQEE 380
E R+ ++ I K+ + S+LQ E+ +K R E E + TN+ +L+ E
Sbjct: 1933 ----EDARRNLQKEIDAKEIAEDAKSNLQREIVE-AKGRLEEESIARTNSDRSRKRLEAE 1987
Query: 381 VTLLNSKLEGMKKSIRMMNKSTNVLE-EILEVGKTVGD-----------MEGIGFSYKSA 428
+ L ++++ +K+ K +E E+ E K G+ +E + YK A
Sbjct: 1988 IDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFLVVEKLETDYKRA 2047
Query: 429 NKSASSEKQTKQPMSDPMLHH 449
K A+ E+Q + + + + H
Sbjct: 2048 KKEAADEQQQRLTVENDLRKH 2068
Score = 45.8 bits (107), Expect = 4e-04
Identities = 74/326 (22%), Positives = 134/326 (40%), Gaps = 61/326 (18%)
Query: 159 SEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSI 218
S++KL + + A EE + +VDEL L + +LN SEKK KS+
Sbjct: 1618 SKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNA-SEKKIKSL 1676
Query: 219 TFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKD 278
V+ +E ++Q E + A L KA ++L + V D + + +++ +L+D
Sbjct: 1677 --VAEVDEVKEQLEDEILAK-----DKLVKAKRAL-EVELEEVRDQLEEE-EDSRSELED 1727
Query: 279 KHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKD 338
TT+ +K D +++L + L + E+ +K++ +
Sbjct: 1728 SKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDE-------KKKLNE 1780
Query: 339 LIAEKKQLQSNN----SSLQEEVKTISKLREENEKLQ---------------------IT 373
KK+L+S N + L EVK S+ ++ +K + I
Sbjct: 1781 SERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIG 1840
Query: 374 NAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLE--------EILEVGK-----------T 414
AKL++++ L SKLE + +KS LE +I + GK
Sbjct: 1841 AAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRAL 1900
Query: 415 VGDMEGIGFSYKSANKSASSEKQTKQ 440
G++E + + + A S S +Q+K+
Sbjct: 1901 EGELEELRETVEEAEDSKSEAEQSKR 1926
Score = 45.8 bits (107), Expect = 4e-04
Identities = 63/270 (23%), Positives = 116/270 (42%), Gaps = 35/270 (12%)
Query: 144 IRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTF 203
++D ++ L + EK +L +D K A+E + I+V+++ L
Sbjct: 858 LKDTESNVLDLQRQLKAEK------ETLKAMYDSK-DALEAQKRELEIRVEDMESELDEK 910
Query: 204 EMSLNGRSEKKAKSITFVSNTEED--EDQREKDTDANIAEAVSLLNKALKSLGRMSNTNV 261
+++L +K V + EE+ E+Q+ ++T L K + L M N
Sbjct: 911 KLALENLQNQKRSVEEKVRDLEEELQEEQKLRNT------LEKLKKKYEEELEEMKRVN- 963
Query: 262 LDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAK 321
D SD + E ++KD+ + + + S +E S D+ L +T L ++
Sbjct: 964 -DGQSDTISRLE-KIKDELQKEVEELTE---------SFSEESK-DKGVLEKTRVRLQSE 1011
Query: 322 WEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEV--KTISKLREENEKLQITNAKLQE 379
++ + + K+ +L+ +KK+L+ +QE + +T +KL +E N KLQ
Sbjct: 1012 LDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQE-----AANKKLQG 1066
Query: 380 EVTLLNSKLEGMKKSIRMMNKSTNVLEEIL 409
E T LN K + + KS LE L
Sbjct: 1067 EYTELNEKFNSEVTARSNVEKSKKTLESQL 1096
Score = 38.1 bits (87), Expect = 0.075
Identities = 43/200 (21%), Positives = 93/200 (46%), Gaps = 33/200 (16%)
Query: 214 KAKSITFVSNTEEDEDQREKDT---DANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVK 270
KA+ + N E++ ++E++ +N+ ++ + +K KSL + + +NVLD
Sbjct: 816 KARPLLKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSL-KDTESNVLD------- 867
Query: 271 NTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGE 330
Q + K E +T KA+ Y ++ + + EL + + ++ +E + E
Sbjct: 868 ---LQRQLKAEKETLKAM---------YDSKDALEAQKRELEIRVEDMESELDEKKLALE 915
Query: 331 KMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEG 390
++ + K+ ++ L+EE++ KLR EKL+ K +EE+ + +G
Sbjct: 916 NLQNQ-------KRSVEEKVRDLEEELQEEQKLRNTLEKLK---KKYEEELEEMKRVNDG 965
Query: 391 MKKSIRMMNKSTNVLEEILE 410
+I + K + L++ +E
Sbjct: 966 QSDTISRLEKIKDELQKEVE 985
Score = 38.1 bits (87), Expect = 0.075
Identities = 60/278 (21%), Positives = 120/278 (42%), Gaps = 38/278 (13%)
Query: 180 TAIEEAQDISNIKVDELIGSL-QTFEMSLNGRSEKKAKSITFVS-----NTEEDEDQREK 233
TA + AQ+ +N K+ L + F + RS + T S N E DE+++ +
Sbjct: 1051 TAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNR 1110
Query: 234 DTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKAL 293
D L K K+L M L+ + D +++T + K ++ + ++AL
Sbjct: 1111 DA----------LEKKKKALDAM-----LEEMKDQLESTGGEKKSLYDLKVKQESDMEAL 1155
Query: 294 IGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQ------LQ 347
+ S+ +S+ E++ T + +A+ + GE +++ EK++ L+
Sbjct: 1156 RNQ-ISELQSTIAKLEKIKSTLEGEVAR-----LQGELEAEQLAKSNVEKQKKKVELDLE 1209
Query: 348 SNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLEE 407
++ L EE L + +KL+ +++Q +++ N+K + + + S N L+
Sbjct: 1210 DKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKL 1269
Query: 408 ILEV-GKTVGDME----GIGFSYKSANKSASSEKQTKQ 440
LE K +E G+ K N+ EK+ K+
Sbjct: 1270 ELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKE 1307
Score = 32.0 bits (71), Expect = 5.4
Identities = 56/266 (21%), Positives = 113/266 (42%), Gaps = 39/266 (14%)
Query: 175 FDMKVTAIEEAQDISNIKVDEL---IGSLQTFEMSLNG-----RSEKKAKSITFVSNTEE 226
+D+KV + + + N ++ EL I L+ + +L G + E +A+ + SN E+
Sbjct: 1142 YDLKVKQESDMEALRN-QISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLA-KSNVEK 1199
Query: 227 DEDQRE---KDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKNTEFQLKDKHEND 283
+ + E +D A +AE + +AL L + L+ V+ + +K+ N
Sbjct: 1200 QKKKVELDLEDKSAQLAEETAA-KQALDKLKKK-----LEQELSEVQTQLSEANNKNVNS 1253
Query: 284 TTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKD-LIAE 342
+ H++ + E+ ++ L E+ + E K V + L E
Sbjct: 1254 DSTNKHLETSFNNLKLELEAEQKAKQAL-----------EKKRLGLESELKHVNEQLEEE 1302
Query: 343 KKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKS----IRMM 398
KKQ +SN + K +S+L+++ E+ + + E S+L+ +K+ +
Sbjct: 1303 KKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSR 1362
Query: 399 NKSTNVLEEIL----EVGKTVGDMEG 420
+KS L+ + E+ T + EG
Sbjct: 1363 DKSVEQLKTLQAKNEELRNTAEEAEG 1388
>DYNA_MOUSE (O08788) Dynactin 1 (150 kDa dynein-associated
polypeptide) (DP-150) (DAP-150) (p150-glued)
Length = 1281
Score = 48.9 bits (115), Expect = 4e-05
Identities = 56/290 (19%), Positives = 128/290 (43%), Gaps = 54/290 (18%)
Query: 154 LGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNGRSEK 213
L P EE+ R +R L ++ ++ ++ ++D + +K L+ ++ L E
Sbjct: 210 LPSPSKEEEGLRAQVRDLEEK--LETLRLKRSEDKAKLK------ELEKHKIQLEQVQEW 261
Query: 214 KAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNT--------NVLDNV 265
K+K + + D +R K+ EA+ + ++ + ++ + +
Sbjct: 262 KSK----MQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEER 317
Query: 266 SDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEES 325
+++++ LK++ + TT +KA I + SD +S ++L
Sbjct: 318 AESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQL-------------- 363
Query: 326 CMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNA---KLQEEVT 382
E+ +KD + + L S S QE VK + ++N++L++ +LQEE++
Sbjct: 364 ----EEQNARLKDALVRMRDLSS--SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 417
Query: 383 LLNSKLEGMKKSI-----------RMMNKSTNVLEEILEVGKTVGDMEGI 421
S ++ +K+ + + +++ N+ E++ E+ +TVGD+E +
Sbjct: 418 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAM 467
>MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B)
Length = 1966
Score = 48.5 bits (114), Expect = 6e-05
Identities = 75/369 (20%), Positives = 164/369 (44%), Gaps = 59/369 (15%)
Query: 95 TVAKEAWEILKTAHEGTSKVRMSKLQLLTT--QFETMKMNEDESIYEFHMRIRDLANSTF 152
++AKE ++ K E ++K+ K L T +T + +E + + + +D +
Sbjct: 874 SLAKEE-KLRKELEESSAKLVEEKTSLFTNLESTKTQLSDAEERLAKLEAQQKDASKQLS 932
Query: 153 ALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLN-GRS 211
L + +++ + ++ K+ + +V A+++ +Q EMSL S
Sbjct: 933 ELNDQLADNEDRTADVQRAKKKIEAEVEALKK--------------QIQDLEMSLRKAES 978
Query: 212 EKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVSDNVKN 271
EK++K S +E + Q E A++ LNK K ++ + D S+ K
Sbjct: 979 EKQSKDHQIRSLQDEMQQQDE---------AIAKLNKEKKHQEEINRKLMEDLQSEEDKG 1029
Query: 272 TEFQLKDKHENDTTKAIHVKALIGKCYSDAESS---------DGDEEELVETYKLLLAKW 322
H+N VKA + + D E S D D+++ +L +A
Sbjct: 1030 N-------HQNK------VKAKLEQTLDDLEDSLEREKRARADLDKQKRKVEGELKIA-- 1074
Query: 323 EESCMYGEKMRKEVKDLIAEKK-QLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEV 381
+E+ + R ++++ + +K+ +L S +S L++E +SKL+ + + Q ++L+EE
Sbjct: 1075 QENIDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEE- 1133
Query: 382 TLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASSE-KQTKQ 440
L ++ + K+ R +++ E+ E+G+ + + G + NK +E + ++
Sbjct: 1134 --LENERQSRSKADR---AKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLRR 1188
Query: 441 PMSDPMLHH 449
+ + ++H
Sbjct: 1189 DLEEANMNH 1197
Score = 40.4 bits (93), Expect = 0.015
Identities = 67/348 (19%), Positives = 139/348 (39%), Gaps = 48/348 (13%)
Query: 124 TQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIE 183
++ E NE +S + DL LGE + E+ A + K+ + ++ +
Sbjct: 1128 SELEEELENERQSRSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAKLR 1187
Query: 184 EAQDISNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAV 243
+ +N+ + +G L+ ++ A+ + + + + EKD + +A
Sbjct: 1188 RDLEEANMNHENQLGGLR------KKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAE 1241
Query: 244 SLLNKA-LKSLGRMSNTNVLDNVSDNVKNTEFQLKD---KHENDTTKAIHVKALIGKCYS 299
L + ++ G+++N + K E QL + K + + + +L G+ +S
Sbjct: 1242 DLAAQLDQETSGKLNNEKL-------AKQFELQLTELQSKADEQSRQLQDFTSLKGRLHS 1294
Query: 300 D-------AESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSS 352
+ E ++ +L L ++ EE+ ++ +E + + A+ K Q
Sbjct: 1295 ENGDLVRQLEDAESQVNQLTRLKSQLTSQLEEARRTADEEARERQTVAAQAKNYQHEAEQ 1354
Query: 353 LQEEV--------KTISKLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNV 404
LQE + + + +L + N +Q A+ + E L +LE K R + N
Sbjct: 1355 LQESLEEEIEGKNEILRQLSKANADIQQWKARFEGEGLLKADELEDAK---RRQAQKINE 1411
Query: 405 LEEILEV------------GKTVGDMEGIGFSYKSANKSASS-EKQTK 439
L+E L+ + VGD++ + AN AS+ EK+ K
Sbjct: 1412 LQEALDAANSKNASLEKTKSRLVGDLDDAQVDVERANGVASALEKKQK 1459
Score = 38.5 bits (88), Expect = 0.057
Identities = 77/412 (18%), Positives = 150/412 (35%), Gaps = 69/412 (16%)
Query: 49 IASTTELKPE------DKWTKKEDDEALGNSKALNVIFNGVDKNMFRLINTCTVAKEAWE 102
+AS E K + D+W KK DD L +G +++ AK A E
Sbjct: 1450 VASALEKKQKGFDKIIDEWRKKTDD--------LAAELDGAQRDLRNTSTDLFKAKNAQE 1501
Query: 103 ILKTAHEGTSKVRMSKLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEK 162
L EG + S Q + + + S++E IR L L + E +
Sbjct: 1502 ELAEVVEGLRRENKSLSQEIKDLTDQLGEG-GRSVHEMQKIIRRLEIEKEELQHALDEAE 1560
Query: 163 LARKILRSLPKRFDMKVTAI---------EEAQDISNIKVDELIGSLQTFEMSLNGRSEK 213
A + S R ++V+ I E+ ++ N + + +L++ + SL ++
Sbjct: 1561 AALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHA-RALESMQASLETEAKG 1619
Query: 214 KAKSITFVSNTEEDEDQREKDTD-ANIAEAVSLLN------------------------- 247
KA+ + E D ++ E D AN A A + N
Sbjct: 1620 KAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQRNGADT 1679
Query: 248 ---------KALKSLGRMSNTNVLDNVSDNV-KNTEFQLKDKHENDTTKAIHVKALIG-- 295
+A V + ++ K E++ D + V +L
Sbjct: 1680 REQFFNAEKRATLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQVSSLTSAK 1739
Query: 296 -KCYSDAESSDGDEEELVETYKLLLAKWEESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQ 354
K + ++ D +E + YK + +++ ++ +E++ + + L+
Sbjct: 1740 RKLEGEIQAIHADLDETLNEYKAAEERSKKAIADATRLAEELRQEQEHSQHVDRLRKGLE 1799
Query: 355 EEVKTISKLREENEKLQITN-----AKLQEEVTLLNSKLEGMKKSIRMMNKS 401
+++K I +E E + AKL++ V L S+L+G ++ + NK+
Sbjct: 1800 QQLKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKN 1851
Score = 36.6 bits (83), Expect = 0.22
Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 306 GDEEELVETYKLLLAKWEESCMYGEKMRKEVKD----LIAEKKQLQSNNSSLQEEVKTIS 361
G E E +E + E+S EK+RKE+++ L+ EK L +N S + + +S
Sbjct: 855 GKEAEELEKINDKVKALEDSLAKEEKLRKELEESSAKLVEEKTSLFTNLESTKTQ---LS 911
Query: 362 KLREENEKLQITNAKLQEEVTLLNSKLEGMKKSIRMMNKSTNVLE-EILEVGKTVGDMEG 420
E KL+ ++++ LN +L + + ++ +E E+ + K + D+E
Sbjct: 912 DAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQIQDLE- 970
Query: 421 IGFSYKSANKSASSEKQTK 439
+ + A SEKQ+K
Sbjct: 971 ------MSLRKAESEKQSK 983
>PUMA_PARUN (O61308) 227 kDa spindle- and centromere-associated
protein (PUMA1)
Length = 1955
Score = 47.8 bits (112), Expect = 9e-05
Identities = 67/354 (18%), Positives = 148/354 (40%), Gaps = 40/354 (11%)
Query: 118 KLQLLTTQFETMKMNEDESIYEFHMRIRDLANSTFALGEPMSEEKLARKILRSLPKRFDM 177
+++ L F T + + +S+ + +++ L + E+L R +L++ D+
Sbjct: 1473 RVKALMAAFATERQSLSDSLKKLASQLQISETKNADLRD--DAERLKRDLLKAERVEEDL 1530
Query: 178 KVTAIEEAQDI-SNIKVDELIGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTD 236
+ +E+ + + N ++ +G Q+ + +GR ++ + V D Q D
Sbjct: 1531 RRNLVEQTEIMRENQQLRSQLGVAQSDLANASGRKQQLEGELAAVRAELRDHKQHLHDAI 1590
Query: 237 ANIAEAVSLLNKALKSLGRMSNTNV-LDNVSDNVKNTEFQLKDKHEN--DTTKAIH---- 289
+ IAE L A R+++ + L+ ++NTE +L+ + D KA++
Sbjct: 1591 SRIAELQRQLQDANAEKSRLTDRIIGLEKTIGTLRNTETELRAQLSTAADERKALNSELE 1650
Query: 290 -VKALIGKCYSDAESSDGDEEE-----LVETYKLLLAKWE---------ESCMYGEKMRK 334
++ I + S+ + D EE ++ T K+ + + E E+ E + +
Sbjct: 1651 EMRRRIVQMESEKKDVDNQLEEVNKARIIMTKKIEILETEKHSAELVISETASQREAIER 1710
Query: 335 EVKDLIAEKKQLQSNNSSLQEEVKTI------------SKLREENEKL--QITNAKLQEE 380
+ L E K+L N + LQ+++ + +K +E++EK + K+Q E
Sbjct: 1711 SLNALERENKELYKNCAQLQQQIAQLEMDNGERLIALTTKQKEDHEKFVAAVKAEKVQVE 1770
Query: 381 VTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGKTVGDMEGIGFSYKSANKSASS 434
++ ++ K IR + +++ E L+ + F N+ SS
Sbjct: 1771 -RIVENRDRAQKSRIRQLENQLSMMREQLDNERARSHQMSERFIVNETNRRVSS 1823
Score = 40.0 bits (92), Expect = 0.020
Identities = 70/345 (20%), Positives = 146/345 (42%), Gaps = 53/345 (15%)
Query: 95 TVAKEAWEILKTAHEGTSKVRM---SKLQLLTTQFETMKMNEDE------SIYEFHM--- 142
TV + E + +A + KV + S ++L +Q E +K ++E +I F +
Sbjct: 1358 TVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQRDEERRNLKSNIVTFELEAR 1417
Query: 143 ----RIRDLANSTFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEA--QDISNIKVDEL 196
+IR L + + + + + LR ++++ +E+ D +V L
Sbjct: 1418 AKDAQIRHLNDLLKRVQAELENSQNDNRALRERQEQYETNRIHLEQRLPTDEGEPRVKAL 1477
Query: 197 IGSLQTFEMSLNGRSEKKAKSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRM 256
+ + T SL+ +K A + +S T+ +A++ + L + L R+
Sbjct: 1478 MAAFATERQSLSDSLKKLASQLQ-ISETK----------NADLRDDAERLKRDLLKAERV 1526
Query: 257 SNTNVLDNVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYK 316
D +N Q + EN +++ +G SD ++ G +++L
Sbjct: 1527 EE--------DLRRNLVEQTEIMRENQ-----QLRSQLGVAQSDLANASGRKQQLEGELA 1573
Query: 317 LLLAKWEESCMYGE-------KMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEK 369
+ A+ + + +++++++D AEK +L L+ KTI LR +
Sbjct: 1574 AVRAELRDHKQHLHDAISRIAELQRQLQDANAEKSRLTDRIIGLE---KTIGTLRNTETE 1630
Query: 370 LQITNAKLQEEVTLLNSKLEGMKKSI-RMMNKSTNVLEEILEVGK 413
L+ + +E LNS+LE M++ I +M ++ +V ++ EV K
Sbjct: 1631 LRAQLSTAADERKALNSELEEMRRRIVQMESEKKDVDNQLEEVNK 1675
Score = 38.9 bits (89), Expect = 0.044
Identities = 39/211 (18%), Positives = 85/211 (39%), Gaps = 21/211 (9%)
Query: 210 RSEKKAKSITFVSNTEEDEDQREKDTDA------NIAEAVSLLNKALKSLGRMSNTNVLD 263
R+E + + S E++ DQR +D D+ + +S + K L+
Sbjct: 902 RAEMATVELKYQSEVEDERDQRSRDADSWKVTSEELRSKISFMEKMLEEAKHRETV---- 957
Query: 264 NVSDNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWE 323
++ + ++KH+ + +++ ++ I + SDAE ++ V + L E
Sbjct: 958 -----LREEATEWEEKHDIISNESLKLRNEIERIRSDAEEDIQKWKKDVHMAQNELKNLE 1012
Query: 324 ESCMYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKLQEEVTL 383
C E +R + L A ++ S N+++ E+ I +L +L+ A + +
Sbjct: 1013 RVC---ETLRSQ---LTAANDRVASLNTTINEQTSKIRELNSHEHRLEEDLADSRATSSA 1066
Query: 384 LNSKLEGMKKSIRMMNKSTNVLEEILEVGKT 414
+ + L +R + +L+ KT
Sbjct: 1067 IENDLGNATGRLRSSEEHNAILQSENRKSKT 1097
Score = 33.5 bits (75), Expect = 1.8
Identities = 57/333 (17%), Positives = 138/333 (41%), Gaps = 41/333 (12%)
Query: 95 TVAKEAWEILKTAHEGTSKVRMSKLQLLTTQFETMKMNE-----DESIYEFHMRIRDLAN 149
TV +E +I ++ + V +LQ++ + E M + D ++ ++ L N
Sbjct: 647 TVRRE--DIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLNDELDTNVKTGQAKVTSLEN 704
Query: 150 STFALGEPMSEEKLARKILRSLPKRFDMKVTAIEEAQDISNIKVDELIGSLQTFEMSLNG 209
S ++ +++ L +L + + +I ++ ++ VD L L+ E +
Sbjct: 705 SIISVQTEVTK-------LTTLNDKLQKEKQSIMSSKQKADTDVDLLKEKLRKLEQECDK 757
Query: 210 -RSEKKA--KSITFVSNTEEDEDQREKDTDANIAEAVSLLNKALKSLGRMSNTNVLDNVS 266
+ E KA + ++E R + ++ +A++ + + K L +M
Sbjct: 758 LKEENKALHEDEQIARQMCKEEASRIHLLERDLKDAMTEVEELKKQLQKMDE-------- 809
Query: 267 DNVKNTEFQLKDKHENDTTKAIHVKALIGKCYSDAESSDGDEEELVETYKLLLAKWEESC 326
+N + E L+ K +DT + AE ++ +EL E YK L + + +
Sbjct: 810 ENSERLESVLRTKISSDTVDTSEI----------AEYTEVKVKELREKYKADLERLQSNK 859
Query: 327 MYGEKMRKEVKDLIAEKKQLQSNNSSLQEEVKTISKLREENEKLQITNAKL------QEE 380
E+ + ++D +AE++++ + ++K +L + + ++ +L ++E
Sbjct: 860 DDLERRVQILEDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMATVELKYQSEVEDE 919
Query: 381 VTLLNSKLEGMKKSIRMMNKSTNVLEEILEVGK 413
+ + K + + + +E++LE K
Sbjct: 920 RDQRSRDADSWKVTSEELRSKISFMEKMLEEAK 952
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.311 0.127 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,668,994
Number of Sequences: 164201
Number of extensions: 3145826
Number of successful extensions: 13742
Number of sequences better than 10.0: 676
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 603
Number of HSP's that attempted gapping in prelim test: 11743
Number of HSP's gapped (non-prelim): 1959
length of query: 667
length of database: 59,974,054
effective HSP length: 117
effective length of query: 550
effective length of database: 40,762,537
effective search space: 22419395350
effective search space used: 22419395350
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Lotus: description of TM0075.5