BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0074.3
         (267 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

DIOL_ARATH (Q949R4) 4,5-DOPA dioxygenase extradiol-like protein       376  e-104
DODA_PORGR (Q7XA48) 4,5-DOPA dioxygenase extradiol (EC 1.13.-.-)      327  2e-89
YGID_ECOLI (P24197) Hypothetical protein ygiD                         169  5e-42
MQO_SYNPX (Q7U5L7) Probable malate:quinone oxidoreductase (EC 1....    33  0.94
YG56_ARCFU (O28617) Hypothetical protein AF1656 precursor              32  1.2
DAD1_PSEAE (Q9HTQ0) D-amino acid dehydrogenase 1 small subunit (...    31  3.6
GIDB_THEMA (Q9WZG6) Methyltransferase gidB (EC 2.1.-.-) (Glucose...    30  4.7
CN5A_ARATH (Q9FVU9) COP9 signalosome complex subunit 5a (EC 3.4....    30  4.7
MM01_HUMAN (P03956) Interstitial collagenase precursor (EC 3.4.2...    30  6.1
YD49_SULTO (Q971K8) Hypothetical UPF0219 protein ST1349                30  8.0
SP8_HUMAN (Q8IXZ3) Transcription factor Sp8 (Specificity protein 8)    30  8.0

>DIOL_ARATH (Q949R4) 4,5-DOPA dioxygenase extradiol-like protein
          Length = 269

 Score =  376 bits (965), Expect = e-104
 Identities = 180/267 (67%), Positives = 221/267 (82%), Gaps = 4/267 (1%)

Query: 3   LKDTFYISHGSPTLSIDESLVARKFLQSWKKEVFPPRPTSILVISGHWDTAVPTVNVVDS 62
           +  TF++SHGSPTLSID+SL AR+F +SW ++V P +P SILVIS HWDT  P+VN V  
Sbjct: 4   VNQTFFLSHGSPTLSIDDSLEARQFFKSWTQKVLPQKPKSILVISAHWDTKFPSVNTV-L 62

Query: 63  TNDTIYDFYGFPKPMYQLKYPAPGAPHLAKRVKELL-KEGGFSRVDEDKKRGLDHGAWVP 121
            N+TI+DF GFP PMY+LKY APGA  L KRVKELL KEGG  RVDED KRGLDHGAWVP
Sbjct: 63  RNNTIHDFSGFPDPMYKLKYEAPGAIELGKRVKELLMKEGGMKRVDEDTKRGLDHGAWVP 122

Query: 122 LLLMYPEADIPVCQLSVQSNLDGTHHYNIGKALAPLKDEGVLIVGSGSAVHNLRALERHA 181
           L+LMYPEADIP+CQLSVQSN +G++HYN+GKALA LKDEGVLI+GSGSA HNLR L+ + 
Sbjct: 123 LMLMYPEADIPICQLSVQSNQNGSYHYNMGKALASLKDEGVLIIGSGSATHNLRKLDFNI 182

Query: 182 TVAA--PWAVEFDNWLKEALLEGRYEDVNHYEQKAPHAKKAHPWPDHFYPLHVAIGAAGE 239
           T  +  PWA+EFD+WL+++LL+GRY DVN +E+KAP+AK AHPWP+H YPLHV +GAAG 
Sbjct: 183 TDGSPVPWALEFDHWLRDSLLQGRYGDVNEWEEKAPNAKMAHPWPEHLYPLHVVMGAAGG 242

Query: 240 NSKAKLIHSSIDLGSLSYASYQFTSDV 266
           ++KA+ IH+S  LG+LSY+SY FTS +
Sbjct: 243 DAKAEQIHTSWQLGTLSYSSYSFTSSL 269


>DODA_PORGR (Q7XA48) 4,5-DOPA dioxygenase extradiol (EC 1.13.-.-)
          Length = 271

 Score =  327 bits (837), Expect = 2e-89
 Identities = 158/265 (59%), Positives = 193/265 (72%), Gaps = 2/265 (0%)

Query: 1   MALKDTFYISHGSPTLSIDESLVARKFLQSWKKEVFPPRPTSILVISGHWDTAVPTVNVV 60
           ++ K++F++SHG+P +  DES +AR FL  WKK VFP +P SILV+S HW+T VP V+  
Sbjct: 7   VSFKESFFLSHGNPAMLADESFIARNFLLGWKKNVFPVKPKSILVVSAHWETDVPCVSAG 66

Query: 61  DSTNDTIYDFYGFPKPMYQLKYPAPGAPHLAKRVKELLKEGGFSRVDEDKKRGLDHGAWV 120
              N  IYDF   P  M+Q+KYPAPG P LAKRV+ELL  GGF     D++RG DH +WV
Sbjct: 67  QYPN-VIYDFTEVPASMFQMKYPAPGCPKLAKRVQELLIAGGFKSAKLDEERGFDHSSWV 125

Query: 121 PLLLMYPEADIPVCQLSVQSNLDGTHHYNIGKALAPLKDEGVLIVGSGSAVHNLRALERH 180
           PL +M PEADIPVCQLSVQ  LD THH+N+G+ALAPLK EGVL +GSG AVH        
Sbjct: 126 PLSMMCPEADIPVCQLSVQPGLDATHHFNVGRALAPLKGEGVLFIGSGGAVHPSDDTPHW 185

Query: 181 ATVAAPWAVEFDNWLKEALLEGRYEDVNHYEQKAPHA-KKAHPWPDHFYPLHVAIGAAGE 239
               APWA EFD WL++ALLEGRYEDVN+Y+ KAP   K AHP P+HF PLHVA+GA GE
Sbjct: 186 FDGVAPWAAEFDQWLEDALLEGRYEDVNNYQTKAPEGWKLAHPIPEHFLPLHVAMGAGGE 245

Query: 240 NSKAKLIHSSIDLGSLSYASYQFTS 264
            SKA+LI+ + D G+L YASY+FTS
Sbjct: 246 KSKAELIYRTWDHGTLGYASYKFTS 270


>YGID_ECOLI (P24197) Hypothetical protein ygiD
          Length = 271

 Score =  169 bits (429), Expect = 5e-42
 Identities = 101/261 (38%), Positives = 153/261 (57%), Gaps = 17/261 (6%)

Query: 8   YISHGSPTLSIDESLVARKFLQSWKK-EVFPPRPTSILVISGHWDTAVPTVNVVDSTNDT 66
           ++ HGSP   ++++L  R    SW+K  +  PRP +I+V+S HW T    V  ++ T  T
Sbjct: 19  FLGHGSPMNVLEDNLYTR----SWQKLGMTLPRPQAIVVVSAHWFTRGTGVTAME-TPPT 73

Query: 67  IYDFYGFPKPMYQLKYPAPGAPHLAKRVKELLKEGGFSRVDEDKKR-GLDHGAWVPLLLM 125
           I+DF GFP+ +Y   YPAPG+P LA+R+ ELL       V  DK+  G DHG+W  L+ M
Sbjct: 74  IHDFGGFPQALYDTHYPAPGSPALAQRLVELLAP---IPVTLDKEAWGFDHGSWGVLIKM 130

Query: 126 YPEADIPVCQLSVQSNLDGTHHYNIGKALAPLKDEGVLIVGSGSAVHNLRALERHATVAA 185
           YP+ADIP+ QLS+ S+     H+ +G+ LA L+DEG+++V SG+ VHNLR ++ H   + 
Sbjct: 131 YPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIMLVASGNVVHNLRTVKWHGDSSP 190

Query: 186 -PWAVEFDNWLKEALL-EGRYED---VNHYEQKAPHAKKAHPWPDHFYPLHVAIGAAGEN 240
            PWA  F+ ++K  L  +G  E    VN+ + +      ++P P+H+ PL   +GA    
Sbjct: 191 YPWATSFNEYVKANLTWQGPVEQHPLVNYLDHEG--GTLSNPTPEHYLPLLYVLGAWDGQ 248

Query: 241 SKAKLIHSSIDLGSLSYASYQ 261
               +    I++GSLS  S Q
Sbjct: 249 EPITIPVEGIEMGSLSMLSVQ 269


>MQO_SYNPX (Q7U5L7) Probable malate:quinone oxidoreductase (EC
           1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO)
          Length = 502

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 25/108 (23%), Positives = 46/108 (42%), Gaps = 1/108 (0%)

Query: 82  YPAPGAPHLAKRVKELLKEGGFSRVDEDKKRGLDHGAWVPLLLMYPEADIPVCQLSVQSN 141
           + A     L +R ++L +   F+ +   ++R  +   W+PL++   +   PV    ++  
Sbjct: 125 WTAENIAFLRQRFEQLSEIPAFAAMRWSEER-TELTDWMPLVMAGRDLKQPVAATRIERG 183

Query: 142 LDGTHHYNIGKALAPLKDEGVLIVGSGSAVHNLRALERHATVAAPWAV 189
            D          L PL+  G L V  G+ V +++ L R     A W V
Sbjct: 184 TDVDFGALTRAYLEPLQRSGALCVEYGTQVRDIKRLRRGDMTEADWRV 231


>YG56_ARCFU (O28617) Hypothetical protein AF1656 precursor
          Length = 144

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/51 (37%), Positives = 24/51 (46%), Gaps = 6/51 (11%)

Query: 47 SGHWDTAV-PTVNVVDSTNDTIYDFYGFPKPMYQLK-----YPAPGAPHLA 91
          SGHW + + PTV+ V   +    DFYG P   Y          APG P L+
Sbjct: 36 SGHWASEIYPTVSFVKKESPVKIDFYGKPNEEYSYDVIFRIVDAPGIPKLS 86


>DAD1_PSEAE (Q9HTQ0) D-amino acid dehydrogenase 1 small subunit (EC
           1.4.99.1)
          Length = 432

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 22/79 (27%), Positives = 34/79 (42%), Gaps = 7/79 (8%)

Query: 154 LAPLKDEGVLIVGSGSAVHNLRALERHATVAAPWAVEFDNWLKEALLEGRYE------DV 207
           L P   +G  IVG+ +   NL     H T+    A     +L + + + R +      D+
Sbjct: 355 LRPATPDGTPIVGA-TRYRNLFLNTGHGTLGWTMACGSGRYLADLMAKKRPQISTEGLDI 413

Query: 208 NHYEQKAPHAKKAHPWPDH 226
           + Y     +AK AHP P H
Sbjct: 414 SRYSNSPENAKNAHPAPAH 432


>GIDB_THEMA (Q9WZG6) Methyltransferase gidB (EC 2.1.-.-) (Glucose
           inhibited division protein B)
          Length = 238

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 15/76 (19%)

Query: 136 LSVQSNLDGTHHYNIGKALAPLKDE--GVLI-VGSGSAVHNLRALERHATVAAPWAVEFD 192
           L+   +LD   H N+ + L PLK+E  G L+ VGSG+ V  L             A+ F 
Sbjct: 47  LTAHRDLDSAVHKNVVEILLPLKEELKGTLLDVGSGNGVPGLIL-----------AIFFS 95

Query: 193 NWLKEALLEGRYEDVN 208
             LK  LL+ R + VN
Sbjct: 96  K-LKVVLLDSREKSVN 110


>CN5A_ARATH (Q9FVU9) COP9 signalosome complex subunit 5a (EC
          3.4.-.-) (Signalosome subunit 5a) (Jun activation
          domain-binding homolog 2)
          Length = 358

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 15/45 (33%), Positives = 25/45 (55%)

Query: 51 DTAVPTVNVVDSTNDTIYDFYGFPKPMYQLKYPAPGAPHLAKRVK 95
          + ++ TV+  DST+D I+ +    +  +Q + P    PH  KRVK
Sbjct: 16 ENSILTVDSPDSTSDNIFYYDDTSQTRFQQEKPWENDPHYFKRVK 60


>MM01_HUMAN (P03956) Interstitial collagenase precursor (EC
           3.4.24.7) (Matrix metalloproteinase-1) (MMP-1)
           (Fibroblast collagenase)
          Length = 469

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 216 HAKKAHPWPDHFYPLHVAIGAAGENSKAKLIHSSIDLGSLSYASYQFTSDV 266
           H  +   W ++F   ++   AA E   +  +  S D+G+L Y SY F+ DV
Sbjct: 196 HFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDV 246


>YD49_SULTO (Q971K8) Hypothetical UPF0219 protein ST1349
          Length = 348

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 42  SILVISGHWDTAVPTVNVVDSTNDTIYDFY---GFPKPMYQLKYPAPGA--PHLAKRVKE 96
           S+  I G  D +   +    S    + DF+   G P P++   +    A   H+   V+ 
Sbjct: 158 SVAYIVGPADESSAIIEYATSYTTDMPDFWRRDGMPYPLHGEAFTGEPAYFAHIISAVQL 217

Query: 97  LLKEGGFSRVDED 109
           LLKEGG+S  D D
Sbjct: 218 LLKEGGYSISDFD 230


>SP8_HUMAN (Q8IXZ3) Transcription factor Sp8 (Specificity protein 8)
          Length = 508

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 13/29 (44%), Positives = 15/29 (50%)

Query: 215 PHAKKAHPWPDHFYPLHVAIGAAGENSKA 243
           P    AHP+   F P H  +GAAGE   A
Sbjct: 195 PRVGMAHPYESWFKPSHPGLGAAGEVGSA 223


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,889,145
Number of Sequences: 164201
Number of extensions: 1572339
Number of successful extensions: 3441
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3425
Number of HSP's gapped (non-prelim): 12
length of query: 267
length of database: 59,974,054
effective HSP length: 108
effective length of query: 159
effective length of database: 42,240,346
effective search space: 6716215014
effective search space used: 6716215014
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)