BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0063.6
(592 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DEK_HUMAN (P35659) DEK protein 115 4e-25
NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa neur... 112 3e-24
NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa neur... 110 1e-23
NFH_MOUSE (P19246) Neurofilament triplet H protein (200 kDa neur... 109 2e-23
NFM_HUMAN (P07197) Neurofilament triplet M protein (160 kDa neur... 103 1e-21
MST2_DROHY (Q08696) Axoneme-associated protein mst101(2) 103 1e-21
NFM_MOUSE (P08553) Neurofilament triplet M protein (160 kDa neur... 101 5e-21
CALD_CHICK (P12957) Caldesmon (CDM) 99 3e-20
MLH_TETTH (P40631) Micronuclear linker histone polyprotein (MIC ... 97 9e-20
UN89_CAEEL (O01761) Muscle M-line assembly protein unc-89 (Uncoo... 95 4e-19
CYL2_BOVIN (Q28092) Cylicin II (Multiple-band polypeptide II) 95 6e-19
NFH_RAT (P16884) Neurofilament triplet H protein (200 kDa neurof... 94 1e-18
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 93 2e-18
NFM_RAT (P12839) Neurofilament triplet M protein (160 kDa neurof... 92 3e-18
CALD_HUMAN (Q05682) Caldesmon (CDM) 92 3e-18
IE68_SHV21 (Q01042) Immediate-early protein 92 4e-18
TRDN_CANFA (P82179) Triadin 89 2e-17
NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 k... 84 1e-15
GARP_PLAFF (P13816) Glutamic acid-rich protein precursor 82 4e-15
CYL1_HUMAN (P35663) Cylicin I (Multiple-band polypeptide I) (Fra... 81 9e-15
>DEK_HUMAN (P35659) DEK protein
Length = 375
Score = 115 bits (287), Expect = 4e-25
Identities = 100/374 (26%), Positives = 172/374 (45%), Gaps = 59/374 (15%)
Query: 99 EDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASER 158
+ E E E G EE +EEE+E + E +E+ K K +G
Sbjct: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEG------------------- 56
Query: 159 PTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHAL 218
RE+K VER ++ S + I +G+G++L +I + F LSK+K D+ L L
Sbjct: 57 -KREKKKVERLTM-----QVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDE-LRNL 109
Query: 219 HSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPV 278
H +L+ + +LK+N+GQFSGF + E Q K +E + K+ L C+VL++
Sbjct: 110 HKLLYNRPGTVSSLKKNVGQFSGFPF-EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLER 168
Query: 279 SKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKK 338
S N EL ++L FL +P+ + K +++K S E ++ A+K
Sbjct: 169 SGVN---SELVKRILNFLMHPKPS---------GKPLPKSKKTCSKGSKKERNSSGMARK 216
Query: 339 QKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQ 398
K+T ++ DE + D K +E+ SDD++ +SEEE K A+
Sbjct: 217 AKRTK--------CPEILSDESSSDEDEKKNKEES-------SDDEDKESEEEPPKKTAK 261
Query: 399 KKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKS 458
++ K+ K S SK ++ + KK ++K + KK + + +++ + + K
Sbjct: 262 REKPKQ--KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL---IKKL 316
Query: 459 KQPASKKRKTENEK 472
K+P + + E K
Sbjct: 317 KKPPTDEELKETIK 330
Score = 113 bits (283), Expect = 1e-24
Identities = 120/465 (25%), Positives = 189/465 (39%), Gaps = 115/465 (24%)
Query: 103 EGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRE 162
E E G EE EE+E+E++ E E +EK +K E K RE
Sbjct: 22 EPEMPGPREESEEEEDEDDEEEEEEEK-----------EKSLIVEGK-----------RE 59
Query: 163 RKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSIL 222
+K VER ++ S + I +G+G++L +I + F LSK+K D+ L LH +L
Sbjct: 60 KKKVERLTMQVSSLQREP-----FTIAQGKGQKLCEIERIHFFLSKKKTDE-LRNLHKLL 113
Query: 223 FGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGN 282
+ + +LK+N+GQFSGF + E Q K +E + K+ L C+VL++ S N
Sbjct: 114 YNRPGTVSSLKKNVGQFSGFPF-EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVN 172
Query: 283 IKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKT 342
EL ++L FL +P+ PS P K KKT
Sbjct: 173 ---SELVKRILNFLMHPK----------------------PSGKP--------LPKSKKT 199
Query: 343 SESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTS 402
G K+ E + AK + + SD+DE K++EE
Sbjct: 200 CSKGSKK------ERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE----------- 242
Query: 403 KKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPA 462
SS + DK ++ PK+TA + SKSK
Sbjct: 243 -------------------------SSDDEDKESEEEPPKKTAKREKPKQKATSKSK--- 274
Query: 463 SKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSG---KKAKAVPSREAMHAVVV 519
K K+ N K K +S+ K+ SSK + + S KK K P+ E + +
Sbjct: 275 -KSVKSANVK---KADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIK 330
Query: 520 DILKEVDFNTATLSDILRQLGTHFGV-DLMHRKAEVKDIITDVIN 563
+L + T+ I +++ ++ DL RK +K + ++I+
Sbjct: 331 KLLASANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKELIS 375
Score = 35.4 bits (80), Expect = 0.42
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 7/113 (6%)
Query: 55 KSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEE 114
K +K++ + K + K + + DE DED + + E +E++
Sbjct: 197 KKTCSKGSKKERNSSGMARKAKRTKCPEILSDE-------SSSDEDEKKNKEESSDDEDK 249
Query: 115 EQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVE 167
E EEE + EK K K K ++A+ KK ++ + +K E
Sbjct: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE 302
Score = 31.6 bits (70), Expect = 6.1
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 14/76 (18%)
Query: 12 PPVQAEGDDAAP-NNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKG--G 68
P + EG P + +E E+ G E E+E EDED E E EEK+K
Sbjct: 6 PAAEGEGTPTQPASEKEPEMPGPREESEEE----EDED-------DEEEEEEEKEKSLIV 54
Query: 69 DQVEEKEEVEKETDEV 84
+ EK++VE+ T +V
Sbjct: 55 EGKREKKKVERLTMQV 70
>NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1026
Score = 112 bits (280), Expect = 3e-24
Identities = 118/502 (23%), Positives = 209/502 (41%), Gaps = 26/502 (5%)
Query: 26 QETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKET-DEV 84
+ET+V E EE++ A +E+ + EAE EE+ K EE EKE V
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK-SPPAEEAASPEKEAKSPV 520
Query: 85 KDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKET 144
K+E K E +++ + E + E+ + +EEA++ + K K K + ++
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580
Query: 145 ASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAF 204
+ K PA ++ P E K+ E+ P ++ + K V E+ + P A
Sbjct: 581 PEKAKSPAKEEAKSPA-EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Query: 205 KLSKR--KPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKY 262
+K K + + ++ +A + ++ ++ EK ++ VK
Sbjct: 640 SPTKEEAKSPEKAKSPEKAKSPEKEEAKSPEKAKSPVK--AEAKSPEKAKSPVKAEAKSP 697
Query: 263 VKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVT 322
K K + + +K +K+E S + + +A T + VK+ +
Sbjct: 698 EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP---EKAKSPVKEEAKSPE 754
Query: 323 PSKSPGEAST--------ETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENV 374
+KSP +A T +TPAK++ ++ K S V+E+ K+ AK +E+
Sbjct: 755 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP-EKAKSPLKEDA 813
Query: 375 AAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDK 434
AP KE K EE + K ++K + VKE E+ + KT K ++
Sbjct: 814 KAPEKEI----PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 869
Query: 435 TPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEK--PDTKGKASSKKQTDKSSKAL 492
PKK PK E + K + +KK + E++K P + +A +K + + +K
Sbjct: 870 APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK 929
Query: 493 VKDQGKSKSGKKAKA-VPSREA 513
K + K AKA PS+ A
Sbjct: 930 EKTEVAKKEPDDAKAKEPSKPA 951
Score = 107 bits (268), Expect = 7e-23
Identities = 132/535 (24%), Positives = 216/535 (39%), Gaps = 52/535 (9%)
Query: 7 EDHNKPPVQA----EGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAE 62
E+ PP + E + +P +E + EA++ EKE A E S E KS A+ E
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE-E 557
Query: 63 EKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
K + EKEE + EVK E+ ++ + E + E+ + +EEA
Sbjct: 558 AKSPPEAKSPEKEEAKSPA-----EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 123 EAEADEKVKAKRGPK-----KGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKS 177
++ A+ K K K K +K + K++ +P + + K+ E+ SP K+
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAKSPEKA 672
Query: 178 AKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIG 237
+ EK + + + S K + + K+ ++
Sbjct: 673 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 732
Query: 238 QFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNI--PVSKGNIKKEELS------ 289
+ + EK ++ VKE K K + L++ P +K K+E S
Sbjct: 733 KEE----AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 788
Query: 290 ----VKLLEFLENPQATTDVLLAD---NEKKVKKRTRKVTPSK---SPGEASTETPAKK- 338
+ E +++P+ L D EK++ K+ +P K P E + P KK
Sbjct: 789 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 848
Query: 339 --QKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSK 396
+K + + K S EE K E K E ++ A + E+K EE EDK K
Sbjct: 849 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 908
Query: 397 A---QKKTSKKI-VKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSAS 452
+K+ K+ VKE +K E+T+ AKK P + K P K K+ AA +
Sbjct: 909 VPTPEKEAPAKVEVKE--DAKPKEKTEVAKKEPDDAKA---KEPSKPAEKKEAAP-EKKD 962
Query: 453 ASLSKSKQPASKKRKTENEKPDTK--GKASSKKQTDKSSKALVKDQGKSKSGKKA 505
K+K+P K + K D K K SK + +K+ K+ DQ SK +KA
Sbjct: 963 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1017
Score = 89.7 bits (221), Expect = 2e-17
Identities = 118/500 (23%), Positives = 199/500 (39%), Gaps = 54/500 (10%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDAS-AEAVKSEAEN 60
A ++ K P +A+ +P +E + E ++ EK +P ++E S AEA E
Sbjct: 550 AKSPAKEEAKSPPEAK----SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 61 AEEKDKGGDQVEEKEEVEKETD---EVKDEVKG-----EEEKDEEDEDGGEGEGEGEGEE 112
+ K++ E K V++E EVK K EE K E E E EE
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEE 665
Query: 113 EEEQEEEE---EAEAEADEKVKAK-RGPKKGGKKETASEKKDPATPASER-PTRER-KTV 166
+ E+ + +AEA++ EK K+ + K +K + K++ +P + P +E K+
Sbjct: 666 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 725
Query: 167 ERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSIL---- 222
E+ P ++ K V E+ + + P A L + P+ A
Sbjct: 726 EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 785
Query: 223 -FGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKG 281
F ++ K+ +K + ++ EK ++ +KE D EK + + + PV K
Sbjct: 786 KFPEKAKS-PVKEEV---------KSPEKAKSPLKE--DAKAPEKEIPKKEEVKSPV-KE 832
Query: 282 NIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTR--------KVTPSKSPGEASTE 333
K +E+ VK + + +K KK KV K P +
Sbjct: 833 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 892
Query: 334 TPAKKQKKTSESGKKRKGSSDVEEDEKAEL-SDAKDESQENVAAPHKESDDDESKSEEEE 392
+ KK KK+ + + E K E+ DAK + + VA K+ DD E +
Sbjct: 893 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA---KKEPDDAKAKEPSK 949
Query: 393 DKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSAS 452
K + KK KE K E+ K+ K +K DKT K K A + + +S
Sbjct: 950 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK-----AKEDDKTLSKEPSKPKAEKAEKSS 1004
Query: 453 ASLSKSKQPASKKRKTENEK 472
++ K +P K + + K
Sbjct: 1005 STDQKDSKPPEKATEDKAAK 1024
Score = 63.5 bits (153), Expect = 1e-09
Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 26/192 (13%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEE--------------KEAAPQEDEDASAEAVKS 56
+PP +AE ++ AP +TE K +++ EE KE A ++ +++ EA K
Sbjct: 843 EPPKKAE-EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 901
Query: 57 EAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKD---EEDEDGGEGEGEGEGEEE 113
EAE DK EKE K EVK++ K +E+ + +E +D E E++
Sbjct: 902 EAE-----DKKKVPTPEKEAPAKV--EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 954
Query: 114 EEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPS 173
E E+++ + E +K + K + K++ + K+P+ P +E+ + T ++ S P
Sbjct: 955 EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP- 1013
Query: 174 PSKSAKSSGGKG 185
P K+ + KG
Sbjct: 1014 PEKATEDKAAKG 1025
Score = 55.5 bits (132), Expect = 4e-07
Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 33/215 (15%)
Query: 331 STETPAKKQKKTSESGKKRKGSSDVEED-EKAELSDAKDESQENVAAPHKESDDDESKSE 389
ST K ++K K K + VEE E+ ++++ E +E A +E ++E E
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK-EAKEEEGKEEEGGEE 491
Query: 390 EE----EDKSK--------AQKKTSKKIVKEGSGS----KAGERTKSAKKTPVKS---SK 430
EE E+++K + +K +K VKE + S K+ E+ ++ VKS +K
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 431 NVDKTPKKSTPKQTAAEHDSASA-----SLSKSKQPASKKRKTENEKPDTKGKASSKKQT 485
+ K KS P+ + E + A + S K+K PA ++ K+ E + S K+
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE 611
Query: 486 DKS---SKALVKDQGKS----KSGKKAKAVPSREA 513
KS +K+ VK++ KS KS +KAK+ EA
Sbjct: 612 AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/241 (21%), Positives = 104/241 (42%), Gaps = 15/241 (6%)
Query: 285 KEELSVKLLEF--LENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKT 342
K E++ +L E+ L N + D+ +A K ++ ++ P P T
Sbjct: 375 KWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVST 434
Query: 343 SESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTS 402
K + VE+ EK + + + V E ++ E+K EE +++ +++ +
Sbjct: 435 HIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEA 494
Query: 403 KKIVKEGSGSKAGERTKSAK--KTPVKSSKNVDKTPKKS-TPKQTAAEHDSASASLSKSK 459
+ +E A E K K+PVK K+P ++ +P++ A+ + S K+K
Sbjct: 495 EGGEEETKSPPAEEAASPEKEAKSPVKEEA---KSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 460 QPASKKRKT-------ENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSRE 512
PA ++ K+ E E+ + + S ++ +K K ++KS +KAK+ E
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE 611
Query: 513 A 513
A
Sbjct: 612 A 612
>NFM_BOVIN (O77788) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Fragment)
Length = 810
Score = 110 bits (274), Expect = 1e-23
Identities = 122/484 (25%), Positives = 208/484 (42%), Gaps = 60/484 (12%)
Query: 26 QETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVK 85
+E E K E E E+E + A A + + E E++++ G + EE+EE ++D+ +
Sbjct: 376 EEAEEKEEKEEAEEEVVAAKKSPVKATAPELKEEEGEKEEEEGQEEEEEEEEAAKSDQAE 435
Query: 86 D---EVKGEEEKDE-EDEDGGEGEGEGEGEE-----EEEQEEEEEAEAEADEKVKAKRGP 136
+ E +G EK+E E E+ GE E EGEGEE +EE++ EE+AE A ++ A
Sbjct: 436 EGGSEKEGSSEKEEGEQEEEGETEAEGEGEEAAAEAKEEKKMEEKAEEVAPKEELAAEAK 495
Query: 137 KKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQL 196
+ +K + K P T + + E K+ E S + S +AKS K + +
Sbjct: 496 VEKPEKAKSPVAKSPTTKSPTAKSPEAKSPEAKSPTAKSPTAKSPVAKSPTAKSPEAKSP 555
Query: 197 KDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVK 256
+ A + + P A S + + KA ++ + K
Sbjct: 556 EAKSPTAKSPTAKSPAAKSPAPKSPVEEVKPKA-----------------EAGAEKGEQK 598
Query: 257 ERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKK 316
E++++ KE +K + K+E+ K E P+ + A++ K +
Sbjct: 599 EKVEEEKKE-------------AKESPKEEKAEKK----EEKPKDVPEKKKAESPVKAES 641
Query: 317 RTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAA 376
++ P+K P + S E AK+++K E K K VEE E K+ +E++A
Sbjct: 642 PVKEEVPAK-PVKVSPEKEAKEEEKPQE---KEKEKEKVEEVGGKEEGGLKESRKEDIAI 697
Query: 377 PHKESDDDESKSEEEEDKSKAQ-KKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKT 435
+ + E K EE+E K K + K +V G G+ K K+ K
Sbjct: 698 ----NGEVEGKEEEQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDKSEEK------VV 747
Query: 436 PKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKD 495
K K T+ D A+ ++KS K E+E+ + S+KK +S A+VK+
Sbjct: 748 VTKMVEKITSEGGDGATKYITKSVTVTQKVE--EHEETFEEKLVSTKKVEKVTSHAIVKE 805
Query: 496 QGKS 499
+S
Sbjct: 806 VTQS 809
Score = 77.8 bits (190), Expect = 7e-14
Identities = 129/617 (20%), Positives = 233/617 (36%), Gaps = 122/617 (19%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA 61
AT + +H K VQ + D + E ++ E E+EA ++D +A+ A++ + E +
Sbjct: 43 ATLEMVNHEKAQVQLDSD-----HLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEES 97
Query: 62 E----EKDKGGDQVEE-----KEEVEKETDEVKDEVKGE----EEKDEEDEDGGEGEGEG 108
E DK +++ + E+E ++ +++ E KD D E
Sbjct: 98 SLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEI 157
Query: 109 EGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVER 168
+ E ++ +A+E K + E A + K+ A E R+ ++
Sbjct: 158 RSQLESHSDQNMH---QAEEWFKCRYAKLT----EAAEQNKEAIRSAKEEIAEYRRQLQS 210
Query: 169 YSVPSPS-KSAKSSGGKGLV-IEKGRGEQLKDIPNVAFKLS------------------- 207
S+ S + K S + L IE+ L + +L
Sbjct: 211 KSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQD 270
Query: 208 ----KRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEK-------QRAKVK 256
K D + A +L G+ T+ G +G ++T + Q+ KV+
Sbjct: 271 LLNVKMALDIEIAAYRKLLEGEETRFSTFA---GSITGPLYTHRQPSIAISSKIQKTKVE 327
Query: 257 ERIDKYVKEKLVDFCDVLNIPVSKGNIKK------EELSVKLLEFLENPQATTDVLLADN 310
K + + + + + K +++ EEL+V + E ++ +A +
Sbjct: 328 APKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSVKEEVKEEEAE------EK 381
Query: 311 EKKVKKRTRKVTPSKSPGEAST---------------------ETPAKKQKKTSESGKKR 349
E+K + V KSP +A+ E A K + E G ++
Sbjct: 382 EEKEEAEEEVVAAKKSPVKATAPELKEEEGEKEEEEGQEEEEEEEEAAKSDQAEEGGSEK 441
Query: 350 KGSSDVEEDEKAELSDAKDESQ-ENVAAPHKESDDDESKSEEEEDKSK------------ 396
+GSS+ EE E+ E + + E + E AA KE E K+EE K +
Sbjct: 442 EGSSEKEEGEQEEEGETEAEGEGEEAAAEAKEEKKMEEKAEEVAPKEELAAEAKVEKPEK 501
Query: 397 -----AQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSA 451
A+ T+K + +K+ E K+P S V K+P +P+ + E S
Sbjct: 502 AKSPVAKSPTTKSPTAKSPEAKSPEAKSPTAKSPTAKSP-VAKSPTAKSPEAKSPEAKSP 560
Query: 452 SASLSKSKQPASK----KRKTENEKPDTKGKASSKKQTD------KSSKALVKDQGKSKS 501
+A +K PA+K K E KP + A +Q + K +K K++ K
Sbjct: 561 TAKSPTAKSPAAKSPAPKSPVEEVKPKAEAGAEKGEQKEKVEEEKKEAKESPKEEKAEKK 620
Query: 502 GKKAKAVPSREAMHAVV 518
+K K VP ++ + V
Sbjct: 621 EEKPKDVPEKKKAESPV 637
Score = 53.1 bits (126), Expect = 2e-06
Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 33/176 (18%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQE----TEVKGEAEAEEKEAAPQEDEDASAEAVKSEAE 59
E +E+ K ++ ++ A +E K +AE+ K +P ++E + S +
Sbjct: 599 EKVEEEKKEAKESPKEEKAEKKEEKPKDVPEKKKAESPVKAESPVKEEVPAKPVKVSPEK 658
Query: 60 NAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEE---KDEEDED---GGEGEGEGEGEEE 113
A+E++K ++ +EKE+VE EV G+EE K+ ED GE EG +E
Sbjct: 659 EAKEEEKPQEKEKEKEKVE--------EVGGKEEGGLKESRKEDIAINGEVEG-----KE 705
Query: 114 EEQEEEEEAEAEADEKVKAKRG-------PKKGGKKETASEKKDPATPASERPTRE 162
EEQE +E+ +EK G KKGG K SE+K T E+ T E
Sbjct: 706 EEQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDK---SEEKVVVTKMVEKITSE 758
Score = 53.1 bits (126), Expect = 2e-06
Identities = 45/169 (26%), Positives = 73/169 (42%), Gaps = 23/169 (13%)
Query: 23 PNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEK-------- 74
P ++ E +AE+ KE P + S E E E +EK+K ++VEE
Sbjct: 628 PEKKKAESPVKAESPVKEEVPAKPVKVSPEKEAKEEEKPQEKEKEKEKVEEVGGKEEGGL 687
Query: 75 EEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGE------------GEGEEEEEQEEEEEA 122
+E KE + EV+G+EE+ E E G GE E G+ ++ ++ EE+
Sbjct: 688 KESRKEDIAINGEVEGKEEEQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDKSEEKVV 747
Query: 123 EAEADEKVKAKRG---PKKGGKKETASEKKDPATPASERPTRERKTVER 168
+ EK+ ++ G K K T ++K + E K VE+
Sbjct: 748 VTKMVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 796
Score = 52.8 bits (125), Expect = 3e-06
Identities = 57/195 (29%), Positives = 85/195 (43%), Gaps = 28/195 (14%)
Query: 11 KPPVQAEGDDAAPNNQETEVKG---EAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKG 67
K PV +P + E K ++ + AA + E VK +AE EK
Sbjct: 538 KSPVAKSPTAKSPEAKSPEAKSPTAKSPTAKSPAAKSPAPKSPVEEVKPKAEAGAEK--- 594
Query: 68 GDQVEEKEEVEKETDEVKDEVKGE--EEKDEEDEDGGEGEGEGEGE-------------- 111
G+Q E+ EE +KE E E K E EEK ++ + + E + E
Sbjct: 595 GEQKEKVEEEKKEAKESPKEEKAEKKEEKPKDVPEKKKAESPVKAESPVKEEVPAKPVKV 654
Query: 112 --EEEEQEEEEEAEAEAD-EKVKAKRGPKKGGKKETASEKKDPATPAS-ERPTRERKTVE 167
E+E +EEE+ E E + EKV+ G ++GG KE S K+D A E E++T E
Sbjct: 655 SPEKEAKEEEKPQEKEKEKEKVEEVGGKEEGGLKE--SRKEDIAINGEVEGKEEEQETKE 712
Query: 168 RYSVPSPSKSAKSSG 182
+ S K ++G
Sbjct: 713 KGSGGEEEKGVVTNG 727
>NFH_MOUSE (P19246) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1087
Score = 109 bits (272), Expect = 2e-23
Identities = 133/528 (25%), Positives = 214/528 (40%), Gaps = 60/528 (11%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQ 70
+P AE A VK EA+ A E S KS AE A+ +
Sbjct: 565 EPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAE-AKSPAEAKSP 623
Query: 71 VEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKV 130
E K E ++ VK E E E + E + E + AE ++ +
Sbjct: 624 AEAKSPAEAKSPAT---VKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEA 680
Query: 131 KAKRGPKKGGKKETASEKKDPA---TPASERPTRERKTVERYSVPSPSKSAKSSGGKGLV 187
K+ PK + ++ +E K PA +PA + E K+ P+ +KS + G
Sbjct: 681 KSPAEPKSPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGEA 740
Query: 188 IEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTEN 247
G + + + A S + A + G ++ A ++
Sbjct: 741 KSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAKSPAE--------------AKS 786
Query: 248 EEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLL 307
EK ++ VKE I + K + PV +G E+ K L+ +++P+A T V
Sbjct: 787 PEKAKSPVKEDIKPPAEAKSPEKA---KSPVKEGAKPPEK--AKPLD-VKSPEAQTPV-- 838
Query: 308 ADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSE--SGKKRKGSSDVEEDEKAELSD 365
E V R KSP + ++P K++ KTSE + KK + S V+E+ KA+
Sbjct: 839 -QEEATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEPP 897
Query: 366 AKDESQENVAAPH---KESDDDESKSEEEEDKSKAQKKTS----KKIVKEGSGSKAGERT 418
K E ++ + P KES DE+ E + K + +K+T K E +AGE+
Sbjct: 898 KKVEEEKTLPTPKTEAKESKKDEAPKEAPKPKVEEKKETPTEKPKDSTAEAKKEEAGEKK 957
Query: 419 K---SAKKTPVKSSKNVDKTPKKST------PKQTAAEHDSASASLSKSKQ---PASKKR 466
K S ++TP K + PK+ T + T A+ S K K+ PA+ ++
Sbjct: 958 KAVASEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKEPSKPTETEKPKKEEMPAAPEK 1017
Query: 467 K-------TENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA 507
K TE+ KP+ K K +K + D K+L K+ K K+ K K+
Sbjct: 1018 KDTKEEKTTESRKPEEKPKMEAKVKED--DKSLSKEPSKPKTEKAEKS 1063
Score = 91.3 bits (225), Expect = 6e-18
Identities = 135/548 (24%), Positives = 209/548 (37%), Gaps = 61/548 (11%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVK---GEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
E+ K ++E + Q E++ G E E+KEA QE E+A K E E A
Sbjct: 436 EEMIKVVEKSEKETVIVEGQTEEIRVTEGVTEEEDKEAQGQEGEEAEEGEEKEEEELAAA 495
Query: 64 KDKGGDQVEEKEEVEKET-DEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
EE EKET VK+E K E E E + GE + E +
Sbjct: 496 TSP---PAEEAASPEKETKSRVKEEAKSPGEAKSPGEAKSPAEAKSPGEAKSPGEAKSPG 552
Query: 123 EAEADEKVKAKRGPKKGGKKETASEKKDPAT---PASERPTRERKTVERYSVPSPSKS-- 177
EA++ + K+ PK + ++ +E K PAT P + E K+ P+ +KS
Sbjct: 553 EAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPA 612
Query: 178 -AKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNI 236
AKS E + K V + P + + ++ A
Sbjct: 613 EAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEA-----KSPAEAKSPAE 667
Query: 237 GQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLN-IPVSKGNIKKEELSVKLLEF 295
+ V + E K A+ K + ++ + + V K +VK
Sbjct: 668 AKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAE 727
Query: 296 LENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEAST----------ETPAKKQKKT-SE 344
++P A + E K + +KSP EA + +TP K+ K+ +E
Sbjct: 728 AKSPAAVK----SPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAKSPAE 783
Query: 345 SGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKS-KAQKKTSK 403
+ K S V+ED K A+ +S E +P KE K++ + KS +AQ +
Sbjct: 784 AKSPEKAKSPVKEDIKPP---AEAKSPEKAKSPVKEGAKPPEKAKPLDVKSPEAQTPVQE 840
Query: 404 KIV-------KEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSA----- 451
+ E S A E+ KS +K K+S+ V PKK K E A
Sbjct: 841 EATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKV--APKKEEVKSPVKEEVKAKEPPK 898
Query: 452 ------SASLSKSKQPASKKRKTENEKPDTKGKASSKKQT-DKSSKALVKDQGKSKSGKK 504
+ K++ SKK + E P K K KK+T + K + K ++G+K
Sbjct: 899 KVEEEKTLPTPKTEAKESKKDEAPKEAP--KPKVEEKKETPTEKPKDSTAEAKKEEAGEK 956
Query: 505 AKAVPSRE 512
KAV S E
Sbjct: 957 KKAVASEE 964
Score = 82.0 bits (201), Expect = 4e-15
Identities = 109/492 (22%), Positives = 201/492 (40%), Gaps = 40/492 (8%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQ 70
K P +A+ A + + GEA++ + +P E + + +EA++ E G
Sbjct: 621 KSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPG-- 678
Query: 71 VEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKV 130
E K E ++ E K E E E + GE + + AEA++ V
Sbjct: 679 -EAKSPAEPKSPA---EAKSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAV 734
Query: 131 KAKRGPKKGGKKETASEKKDPA---TPASERPTRERKTVERYSVPSPSKSAKSSGGKGLV 187
K+ K G+ ++ +E K PA +P + + KT + SP+++ K V
Sbjct: 735 KSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAKSPAEAKSPEKAKSPV 794
Query: 188 IEKGRGEQLKDIPNVAFKLSKR--KPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWT 245
E + P A K KP + L +T
Sbjct: 795 KEDIKPPAEAKSPEKAKSPVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQV 854
Query: 246 ENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDV 305
++ K++AK E+ + EK+ + + PV K +K +E K+ E P T+
Sbjct: 855 KSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPV-KEEVKAKEPPKKVEEEKTLPTPKTEA 913
Query: 306 LLADNEK------KVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDE 359
+ ++ K K +K TP++ P +++ E AKK+ E+G+K+K + EE+
Sbjct: 914 KESKKDEAPKEAPKPKVEEKKETPTEKPKDSTAE--AKKE----EAGEKKKAVAS-EEET 966
Query: 360 KAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTK 419
A+L K+E A P ++++ ++++E+ + K ++ ++K KE E
Sbjct: 967 PAKLG-VKEE-----AKPKEKTETTKTEAEDTKAKEPSKPTETEKPKKE-------EMPA 1013
Query: 420 SAKKTPVKSSKNVDKTPKKSTPKQTA-AEHDSASASLSKSKQPASKKRKTENEKPDTKGK 478
+ +K K K + + PK A + D S S SK P ++K + + + +
Sbjct: 1014 APEKKDTKEEKTTESRKPEEKPKMEAKVKEDDKSLSKEPSK-PKTEKAEKSSSTDQKESQ 1072
Query: 479 ASSKKQTDKSSK 490
K DK++K
Sbjct: 1073 PPEKTTEDKATK 1084
Score = 75.1 bits (183), Expect = 5e-13
Identities = 115/499 (23%), Positives = 182/499 (36%), Gaps = 63/499 (12%)
Query: 50 SAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGE 109
S E +K ++ +E Q EE E T+E E +G+E GE E
Sbjct: 435 SEEMIKVVEKSEKETVIVEGQTEEIRVTEGVTEEEDKEAQGQE-----------GEEAEE 483
Query: 110 GEEEEEQE--------EEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPA--------- 152
GEE+EE+E EE A E + K + K K G+ ++ E K PA
Sbjct: 484 GEEKEEEELAAATSPPAEEAASPEKETKSRVKEEAKSPGEAKSPGEAKSPAEAKSPGEAK 543
Query: 153 ------TPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKL 206
+P + E K+ P+ +KS V G + + + A
Sbjct: 544 SPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAK 603
Query: 207 SKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEK 266
S + A +A + E K A VK + +
Sbjct: 604 SPAEAKSPAEAKSPAEAKSPAEAK--------------SPAEAKSPATVKSPGEAKSPSE 649
Query: 267 LVDFCDVLNIPVSKGNIK-KEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPS- 324
+ + +K + K VK ++P A + +VK +P+
Sbjct: 650 AKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAE 709
Query: 325 -KSPGE----ASTETPAKKQ-----KKTSESGKKRKGSSDVEEDEKAEL-SDAKDESQEN 373
KSPGE A+ ++PA+ + K E+ + S E AE S + +S E
Sbjct: 710 VKSPGEAKSPAAVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEK 769
Query: 374 VAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVD 433
P KE ++++ E K+ K + S KA K K P K+
Sbjct: 770 AKTPVKEGAKSPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAKSPVKEGAKPPEKAKPLDV 829
Query: 434 KTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKT-ENEKPDTKGKASSKKQTDKSS-KA 491
K+P+ TP Q A + + K PA +K K+ E E+ T K + KK+ KS K
Sbjct: 830 KSPEAQTPVQEEATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKE 889
Query: 492 LVKDQGKSKSGKKAKAVPS 510
VK + K ++ K +P+
Sbjct: 890 EVKAKEPPKKVEEEKTLPT 908
Score = 72.8 bits (177), Expect = 2e-12
Identities = 96/401 (23%), Positives = 162/401 (39%), Gaps = 29/401 (7%)
Query: 16 AEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKE 75
AE A EVK EA+ A E S AVKS E A+ + E K
Sbjct: 696 AEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGE-AKSPGEAKSPAEAKS 754
Query: 76 EVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE--AEADEKVKAK 133
E ++ EVK E+ ++G + E + E+ + +E+ + AEA KAK
Sbjct: 755 PAEAKSPI---EVKSPEKAKTPVKEGAKSPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAK 811
Query: 134 RGPKKGGKKETASEKKDPATPASERPTRERKTV-------ERYSVPSPSKSAKSSGGKGL 186
K+G K ++ D +P ++ P +E TV E+ P+ K+ +
Sbjct: 812 SPVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQVKSPAKEKAKSPEKEEAK 871
Query: 187 VIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE 246
EK ++ + V ++ ++P + L +T+A K++ +
Sbjct: 872 TSEKVAPKKEEVKSPVKEEVKAKEPPKKVEE-EKTLPTPKTEAKESKKDEAPKEA-PKPK 929
Query: 247 NEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKL-LEFLENPQATTDV 305
EEK+ ++ D + K + + K +EE KL ++ P+ T+
Sbjct: 930 VEEKKETPTEKPKDSTAEAKKEEAGEK-----KKAVASEEETPAKLGVKEEAKPKEKTET 984
Query: 306 LLADNE----KKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGK---KRKGSSDVEED 358
+ E K+ K T P K A+ E K++KT+ES K K K + V+ED
Sbjct: 985 TKTEAEDTKAKEPSKPTETEKPKKEEMPAAPEKKDTKEEKTTESRKPEEKPKMEAKVKED 1044
Query: 359 EKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQK 399
+K+ LS + + A +D ES+ E+ + KA K
Sbjct: 1045 DKS-LSKEPSKPKTEKAEKSSSTDQKESQPPEKTTEDKATK 1084
Score = 65.9 bits (159), Expect = 3e-10
Identities = 63/231 (27%), Positives = 100/231 (43%), Gaps = 25/231 (10%)
Query: 299 PQATTDVLLADNEK-KVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKG-----S 352
P +T + + E KV +++ K T E TE + T E K+ +G +
Sbjct: 425 PSISTHIKVKSEEMIKVVEKSEKETVIV---EGQTEEIRVTEGVTEEEDKEAQGQEGEEA 481
Query: 353 SDVEEDEKAELSDAKDESQENVAAPHKESDD---DESKSEEE-----EDKSKAQKKTSKK 404
+ EE E+ EL+ A E A+P KE+ +E+KS E E KS A+ K+ +
Sbjct: 482 EEGEEKEEEELAAATSPPAEEAASPEKETKSRVKEEAKSPGEAKSPGEAKSPAEAKSPGE 541
Query: 405 IVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTA-------AEHDSASASLSK 457
G GE A+ K+ + + PK A A+ S + S ++
Sbjct: 542 AKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAE 601
Query: 458 SKQPASKKRKTENEKP-DTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA 507
+K PA K E + P + K A +K + S A VK G++KS +AK+
Sbjct: 602 AKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKS 652
Score = 58.5 bits (140), Expect = 5e-08
Identities = 57/227 (25%), Positives = 96/227 (42%), Gaps = 19/227 (8%)
Query: 309 DNEKKVKKRTRKVTPSKSPGEASTETPAK---KQKKTSESGKKRKGSSDVEEDEKAE--- 362
+ + +VK+ + +KSPGEA + AK + K E+ + S E AE
Sbjct: 509 ETKSRVKEEAKSPGEAKSPGEAKSPAEAKSPGEAKSPGEAKSPGEAKSPAEPKSPAEPKS 568
Query: 363 ----LSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKT---SKKIVKEGSGSKAG 415
S A+ +S V +P + E+KS E KS A+ K+ +K + S ++A
Sbjct: 569 PAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEA-KSPAEAKSPAEAKSPAEAKSPAEAK 627
Query: 416 ERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKS----KQPASKKRKTENE 471
++ VKS + +P + + ++ S + +KS K P K E +
Sbjct: 628 SPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPK 687
Query: 472 KP-DTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAV 517
P + K A K + S A VK G++KS K+ ++ AV
Sbjct: 688 SPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAV 734
Score = 57.4 bits (137), Expect = 1e-07
Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 15/189 (7%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEA-------- 58
E+ P + E ++ + E E+KE ++ +D++AEA K EA
Sbjct: 902 EEKTLPTPKTEAKESKKDEAPKEAPKPKVEEKKETPTEKPKDSTAEAKKEEAGEKKKAVA 961
Query: 59 --ENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQ 116
E K ++ + KE+ E E +D E K E E + E E+++ +
Sbjct: 962 SEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKEPSKPTETEKPKKEEMPAAPEKKDTK 1021
Query: 117 EEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSK 176
EE+ + +EK K + K+ K S K+P+ P +E+ + T ++ S P P K
Sbjct: 1022 EEKTTESRKPEEKPKMEAKVKEDDK----SLSKEPSKPKTEKAEKSSSTDQKESQP-PEK 1076
Query: 177 SAKSSGGKG 185
+ + KG
Sbjct: 1077 TTEDKATKG 1085
Score = 56.2 bits (134), Expect = 2e-07
Identities = 66/283 (23%), Positives = 130/283 (45%), Gaps = 20/283 (7%)
Query: 245 TENEEKQ-RAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATT 303
TE E+K+ + + E ++ +++ + + P + ++E ++ E ++P
Sbjct: 466 TEEEDKEAQGQEGEEAEEGEEKEEEELAAATSPPAEEAASPEKETKSRVKEEAKSPGEAK 525
Query: 304 DVLLADNEKKVKKRTRKVTP--SKSPGEAST----ETPAK-KQKKTSESGKKRKGSSDVE 356
A + + K +P +KSPGEA + ++PA+ K ++S + K + V+
Sbjct: 526 SPGEAKSPAEAKSPGEAKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVK 585
Query: 357 EDEKAEL-SDAKDESQENVAAPHKESDDDESKSEEE---EDKSKAQKKTSKKIVKEGSGS 412
+A+ S+AK ++ A K + +S +E + E KS A+ K+ + G
Sbjct: 586 SPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAK 645
Query: 413 KAGERTKSAK-KTPVKSSKNVD-KTPKK-STPKQTAAEHDSASASLSKS----KQPASKK 465
E A+ K+P ++ + K+P + +P + + + S + +KS K PA K
Sbjct: 646 SPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAK 705
Query: 466 RKTENEKP-DTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA 507
E + P + K A+ K + S A VK G++KS +AK+
Sbjct: 706 SPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGEAKSPGEAKS 748
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/208 (23%), Positives = 82/208 (38%), Gaps = 33/208 (15%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAE--------------AEEKEAAPQEDE 47
A +++ KPP +A+ D +T V+ EA A+EK +P+++E
Sbjct: 810 AKSPVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQVKSPAKEKAKSPEKEE 869
Query: 48 DASAEAVKSEAENA------------------EEKDKGGDQVEEKEEVEKETDEVKDEVK 89
++E V + E EEK + E KE + E + + K
Sbjct: 870 AKTSEKVAPKKEEVKSPVKEEVKAKEPPKKVEEEKTLPTPKTEAKESKKDEAPKEAPKPK 929
Query: 90 GEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETA-SEK 148
EE+K+ E + E + EE E+++ +E E K+ K K K ET +E
Sbjct: 930 VEEKKETPTEKPKDSTAEAKKEEAGEKKKAVASEEETPAKLGVKEEAKPKEKTETTKTEA 989
Query: 149 KDPATPASERPTRERKTVERYSVPSPSK 176
+D +PT K + +P K
Sbjct: 990 EDTKAKEPSKPTETEKPKKEEMPAAPEK 1017
Score = 38.5 bits (88), Expect = 0.050
Identities = 37/133 (27%), Positives = 60/133 (44%), Gaps = 12/133 (9%)
Query: 17 EGDDAAPNNQETE----VKGEAEAEEK-EAAPQEDEDASAEAVKSEAENAEEKDKGGDQV 71
E A + +ET VK EA+ +EK E E ED A+ E + K +
Sbjct: 955 EKKKAVASEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKEPSKPTETEKPKKEEMPAA 1014
Query: 72 EEKEEV--EKETDEVKDEVKG--EEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEAD 127
EK++ EK T+ K E K E + E+D+ + + + E+ E+ ++ E++
Sbjct: 1015 PEKKDTKEEKTTESRKPEEKPKMEAKVKEDDKSLSKEPSKPKTEKAEKSSSTDQKESQPP 1074
Query: 128 EKV---KAKRGPK 137
EK KA +G K
Sbjct: 1075 EKTTEDKATKGEK 1087
>NFM_HUMAN (P07197) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M) (Neurofilament 3)
Length = 915
Score = 103 bits (257), Expect = 1e-21
Identities = 126/504 (25%), Positives = 215/504 (42%), Gaps = 51/504 (10%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
E +E+ ++E ++A E E+ + E+KEAA +++E+ AE + A+ +
Sbjct: 454 EIIEETKVEDEKSEMEEALTAITE-ELAASMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 512
Query: 64 KDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE 123
K + EE+ E E+E + ++E + E K ++ E+GG E EG E+EE ++EE E E
Sbjct: 513 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG-SEKEGSSEKEEGEQEEGETE 571
Query: 124 AEAD-EKVKAKRGPKKGGKKETASEKKDPATPAS-ERPTRERKTVERYSVPSPSKSAKSS 181
AEA+ E+ +AK K K E + K++ A E+P + + V + V + KS
Sbjct: 572 AEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV---EEKGKSP 628
Query: 182 GGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSG 241
K V EKG+ +P + + P + ++ K+ K +
Sbjct: 629 VPKSPVEEKGK----SPVPKSPVEEKGKSP------VPKSPVEEKGKSPVSKSPV----- 673
Query: 242 FVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA 301
EEK ++ V + + K K V KG K+EE E E P+
Sbjct: 674 ------EEKAKSPVPKSPVEEAKSK---------AEVGKGEQKEEEEK----EVKEAPKE 714
Query: 302 TTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKA 361
+ K V ++ + +P K A T K K E K +G +E EK
Sbjct: 715 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 774
Query: 362 ELSDAKDESQENVAAPHKES-DDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKS 420
+ +E K S +D + + E E K + +++T +K G + G T
Sbjct: 775 KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEK--GSGREEEKGVVTNG 832
Query: 421 AKKTPVKSSKNVDKTPK-----KSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDT 475
+P K DK+ + K+ K T+ D A+ ++KS K E+E+
Sbjct: 833 LDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVE--EHEETFE 890
Query: 476 KGKASSKKQTDKSSKALVKDQGKS 499
+ S+KK +S A+VK+ +S
Sbjct: 891 EKLVSTKKVEKVTSHAIVKEVTQS 914
Score = 75.1 bits (183), Expect = 5e-13
Identities = 141/663 (21%), Positives = 249/663 (37%), Gaps = 102/663 (15%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA 61
AT + +H K VQ + D + E ++ E E+EA ++D +A+ A++ + E A
Sbjct: 158 ATLEMVNHEKAQVQLDSD-----HLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEEA 212
Query: 62 E----EKDKGGDQVEE-----KEEVEKETDEVKDEVKGE----EEKDEEDEDGGEGEGEG 108
E DK +++ + E+E ++ +++ E KD D E
Sbjct: 213 SLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEI 272
Query: 109 EGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVER 168
+ E ++ +A+E K + E A + K+ A E R+ ++
Sbjct: 273 RSQLESHSDQNMH---QAEEWFKCRYAKLT----EAAEQNKEAIRSAKEEIAEYRRQLQS 325
Query: 169 YSVPSPS-KSAKSSGGKGLV-IEKGRGEQLKDIPNVAFKLS------------------- 207
S+ S + K S + L IE+ L + +L
Sbjct: 326 KSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQD 385
Query: 208 ----KRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE------NEEKQRAKVKE 257
K D + A +L G+ T+ G +G ++T + + Q+ KV+
Sbjct: 386 LLNVKMALDIEIAAYRKLLEGEETRFSTFA---GSITGPLYTHRPPITISSKIQKTKVEA 442
Query: 258 RIDKYVKEKLVDFCDVLNIPVSKGNIKK------EELSVKLLEFL--------ENPQATT 303
K + + + + + K +++ EEL+ + E E P+A
Sbjct: 443 PKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAASMKEEKKEAAEEKEEEPEAEE 502
Query: 304 DVLLADNEK------KVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE 357
+ + A +VK+ + + E E K + E G +++GSS+ EE
Sbjct: 503 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 562
Query: 358 DEKAE-LSDAKDESQENVAAPHK--ESDDDESKSEEE-------EDKSKAQKKTSKKIVK 407
E+ E ++A+ E +E A K E +E ++EE E KA+ K V+
Sbjct: 563 GEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVE 622
Query: 408 EGSGSKAGERTKSAK-KTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLS----KSKQPA 462
E S + K K+PV S V++ K PK E + S S K+K P
Sbjct: 623 EKGKSPVPKSPVEEKGKSPVPKSP-VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 681
Query: 463 SKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVP-SREAMHAVVVDI 521
K E + GK K++ +K K K++ K +K K VP ++A V +
Sbjct: 682 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 741
Query: 522 LKEVDFNTATLSDILRQLGTHFGVDLMHRKAEVKDIITDVINNMSDEEDEGEEADGDGDA 581
+ EV T ++ L + G L K + K E+EG + G
Sbjct: 742 VAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK------AGGEGGSEEEGSDKGAKGSR 795
Query: 582 DKD 584
+D
Sbjct: 796 KED 798
>MST2_DROHY (Q08696) Axoneme-associated protein mst101(2)
Length = 1391
Score = 103 bits (257), Expect = 1e-21
Identities = 132/512 (25%), Positives = 226/512 (43%), Gaps = 41/512 (8%)
Query: 33 EAEAEEKEAAPQEDEDASAEAVKSEAEN--AEEKDKGGDQVEEKEEVEKETDEVKD-EVK 89
EA +EKEAA ++ + A+ +K AE EE K G +V E+++ E+ ++K E+K
Sbjct: 449 EAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIK 508
Query: 90 GEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKK 149
+ +K + E E E+++ E+ + EA EK K ++ KK +KE A +KK
Sbjct: 509 KKCKKLAKKEK--------ETAEKKKCEKAAKKRKEAAEKKKCEKAAKK--RKEAAEKKK 558
Query: 150 DPATP-----ASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQL-KDIPNVA 203
+ A+E+ E+ ER K +++ + V E+ + E+L K I A
Sbjct: 559 CEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAA 618
Query: 204 FK-----LSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKER 258
K +K++ + L K KA K+ T ++K K+R
Sbjct: 619 EKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKR 678
Query: 259 IDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKV--KK 316
+ K+K + K K EE + K E E + LA KK KK
Sbjct: 679 KEAAEKKKCAEAAKKEKEAAEKK--KCEEAAKKEKEAAERKKCEE---LAKKIKKAAEKK 733
Query: 317 RTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAA 376
+ +K+ K GE + K KK ++ K++K ++ + + AE K+ +++ A
Sbjct: 734 KCKKLAKKKKAGEKNKLK--KGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEA 791
Query: 377 PHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTP 436
K+ + +K +EE + K +KT+KK KE + K E+ +K + K +KT
Sbjct: 792 AEKKKCEKTAKKRKEEAEKKKCEKTAKK-RKEAAEKKKCEKAAKKRKEEAE-KKKCEKTA 849
Query: 437 KKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKK--QTDKSSKALVK 494
KK K+TA + A +K ++ A++K+K E K A KK + K K L +
Sbjct: 850 KKR--KETAEKKKCEKA--AKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAE 905
Query: 495 DQGKSKSGKKAKAVPSREAMHAVVVDILKEVD 526
+ ++ KK K V R+ + I K +
Sbjct: 906 KKKCEEAAKKEKEVAERKKCEELAKKIKKAAE 937
Score = 101 bits (252), Expect = 5e-21
Identities = 133/508 (26%), Positives = 209/508 (40%), Gaps = 50/508 (9%)
Query: 19 DDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKD---------KGGD 69
+ +A +E K + E KE ++ EA K E E AE K K +
Sbjct: 560 EKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAE 619
Query: 70 QVEEKEEVEKETDEVKDEVKGEEEKD-----EEDEDGGEGEGEGEGEEEEEQEEEEEAEA 124
+ + KE +KE + + E GE K E+ + + E E E+++ E+ +
Sbjct: 620 KKKCKEAAKKEKEAAEREKCGELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRK 679
Query: 125 EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGK 184
EA EK K KK +KE A +KK E+ ERK E + K+A+ K
Sbjct: 680 EAAEKKKCAEAAKK--EKEAAEKKKCEEAAKKEKEAAERKKCEELA-KKIKKAAEKKKCK 736
Query: 185 GLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVW 244
L +K GE+ K K +K L + KA K+
Sbjct: 737 KLAKKKKAGEKNK------LKKGNKKGKKALKEKKKCRELAKKKAAEKKK----CKEAAK 786
Query: 245 TENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKK--EELSVKLLEFLENPQAT 302
E E ++ K ++ K +E C+ + KK E+ + K E E +
Sbjct: 787 KEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKC- 845
Query: 303 TDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE-DEKA 361
EK KKR K A A ++KK ++ KKRK +++ ++ E A
Sbjct: 846 --------EKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAA 897
Query: 362 ELSDAKDESQENVAAPHKESDDDESKSEEE---EDKSKAQKKTSKKIVKEGSGSKAGERT 418
+ E ++ A KE + E K EE + K A+KK KK+ K+ KAGE+
Sbjct: 898 KKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKK--EKKAGEKN 955
Query: 419 KSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGK 478
K KK K K K KKS + AAE + + K K+ A+KK+ E K + +
Sbjct: 956 KLKKKAG-KGKKKCKKLGKKS---KRAAEKKKCAEAAKKEKEAATKKKCEERAK--KQKE 1009
Query: 479 ASSKKQTDKSSKALVKDQGKSKSGKKAK 506
A+ KKQ ++ +K L + + + ++AK
Sbjct: 1010 AAEKKQCEERAKKLKEAAEQKQCEERAK 1037
Score = 99.0 bits (245), Expect = 3e-20
Identities = 128/531 (24%), Positives = 224/531 (42%), Gaps = 52/531 (9%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKG---EAEAEEKEAAPQEDEDASAEAVKSEAEN 60
E K + + + AA +E K EA +EKEAA ++ + A+ +K AE
Sbjct: 385 EAANKEKKAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEAAERKKCEELAKNIKKAAEK 444
Query: 61 AEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEE 120
+ K+ + E E K+ +E+ ++K EK + +E +G+ E E ++ EE
Sbjct: 445 KKCKEAAKKEKEAAER--KKCEELAKKIKKAAEKKKCEETAKKGK---EVAERKKCEELA 499
Query: 121 EAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVE-----RYSVPSPS 175
+ +A+ K K K+ KK +KETA +KK + E+K E R
Sbjct: 500 KKIKKAEIKKKCKKLAKK--EKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKK 557
Query: 176 KSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRN 235
K KS+ + EK + E+ A + K+K ++ + +R K L +
Sbjct: 558 KCEKSAKKRKEAAEKKKCEKAAKERKEAAE--KKKCEEAAKKEKEV--AERKKCEELAKK 613
Query: 236 IGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKE--ELSVKLL 293
I + + EK++ K + +K E+ + C L + K KK+ +L+ K
Sbjct: 614 IKKAA--------EKKKCKEAAKKEKEAAER--EKCGELAKKIKKAAEKKKCKKLAKKEK 663
Query: 294 EFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSS 353
E E + EK KKR K A E A ++KK E+ KK K ++
Sbjct: 664 ETAEKKKC---------EKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAA 714
Query: 354 D---VEEDEKAELSDAKDESQENVAAPHKESDDDE-SKSEEEEDKSKAQKKTSKKIVKEG 409
+ EE K A+ + + +A K + ++ K ++ K+ +KK +++ K+
Sbjct: 715 ERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKK 774
Query: 410 SGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSAS-----ASLSKSKQPASK 464
+ K + + K+ K +KT KK + + + + A+ K + A+K
Sbjct: 775 AAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAK 834
Query: 465 KRKTENEKPDTKGKASSKKQT---DKSSKALVKDQGKSKSGKKAKAVPSRE 512
KRK E EK + A +K+T K KA K + ++ K KA R+
Sbjct: 835 KRKEEAEKKKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRK 885
Score = 97.4 bits (241), Expect = 9e-20
Identities = 127/525 (24%), Positives = 218/525 (41%), Gaps = 43/525 (8%)
Query: 22 APNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVE-KE 80
A +ET K + E K+ ++ AEA K E E AE+K +EKE E K+
Sbjct: 659 AKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKK 718
Query: 81 TDEVKDEVKGEEEKDE-----EDEDGGE------GEGEGEGEEEEEQEEEEEAEAEADEK 129
+E+ ++K EK + + + GE G +G+ +E+++ E A+ +A EK
Sbjct: 719 CEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEK 778
Query: 130 VKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIE 189
K K KK +KE A +KK T + E+K E+ + + K K
Sbjct: 779 KKCKEAAKK--EKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKR 836
Query: 190 KGRGEQLKDIPNVAFK----LSKRKPDDNLHALHSILFGKRT-KAYNLKRNIGQFSGFVW 244
K E+ K A K K+K + K+ KA ++ +
Sbjct: 837 KEEAEK-KKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAE 895
Query: 245 TENEEKQRAKVKERIDKYVKEKLV---DFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA 301
+EK+ A+ K+ + KEK V C+ L + K KK+ + E +
Sbjct: 896 AAKKEKELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKN 955
Query: 302 TTDVLLADNEKKVKK---RTRKVTPSKSPGEAST-ETPAKKQKKTSESGKKRKGSSDVEE 357
+KK KK ++++ K EA+ E A +KK E KK+K +++ ++
Sbjct: 956 KLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQ 1015
Query: 358 DEK--------AELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEG 409
E+ AE ++ +++ A K+ ++ +K +E + K ++ +KK+ +
Sbjct: 1016 CEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAA 1075
Query: 410 SGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTE 469
+ ER K K+ K K ++ KK + AAE K K+ A KKR E
Sbjct: 1076 EKKQCEERAKKEKEAAEK--KQCEERAKK---LKEAAEKKQCEERAKKEKEAAEKKRCEE 1130
Query: 470 NEKPDTKGKASSKK--QTDKSSKALVKDQGKSKSGKKAKAVPSRE 512
K + K A KK + K K + Q +++ KK K ++
Sbjct: 1131 AAKRE-KEAAEKKKCAEAAKKEKEATEKQKCAEAAKKEKEAAEKK 1174
Score = 96.3 bits (238), Expect = 2e-19
Identities = 132/518 (25%), Positives = 231/518 (44%), Gaps = 69/518 (13%)
Query: 14 VQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEE 73
V AE +AA + +E K + ++K+ +++++ E +K +AE EE G E
Sbjct: 267 VIAEMCEAAGYVKSSEPK--KKGKKKKNDEKKEKELEREILKEQAE--EEAKIRGVVKEV 322
Query: 74 KEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEA--EADEKVK 131
K++ +++ + K + G + K+E ++ + + EE+E++ +E A+ EADEK K
Sbjct: 323 KKKCKEKALKKKCKDLGRKMKEEAEKKKCAALAKKQKEEDEKKACKELAKKKKEADEKKK 382
Query: 132 AKRGPKKGGKKETASEKKDPATPASERPTRERK-TVERYSVPSPSKSAKSSGGKGLVIEK 190
+ K +K+ A +KK E+ +ERK E+ +K K + E+
Sbjct: 383 CEEAANK--EKKAAEKKK------CEKAAKERKEAAEKKKCEEAAKKEKEAA------ER 428
Query: 191 GRGEQL-KDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEE 249
+ E+L K+I A K ++ A +R K L + I + + E
Sbjct: 429 KKCEELAKNIKKAAEKKKCKEA-----AKKEKEAAERKKCEELAKKIKKAA--------E 475
Query: 250 KQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKK--EELSVKLLEFLENPQATTDVLL 307
K++ + + K V E+ C+ L + K IKK ++L+ K E E +
Sbjct: 476 KKKCEETAKKGKEVAER--KKCEELAKKIKKAEIKKKCKKLAKKEKETAEKKKC------ 527
Query: 308 ADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKA--ELSD 365
EK KKR K A A ++KK +S KKRK +++ ++ EKA E +
Sbjct: 528 ---EKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKE 584
Query: 366 AKDESQENVAAPHKESDDDESKSEE--EEDKSKAQKKTSKKIVKE----GSGSKAGERTK 419
A ++ + AA ++ + K EE ++ K A+KK K+ K+ K GE K
Sbjct: 585 AAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAEREKCGELAK 644
Query: 420 SAKKTPVKSS-KNVDKTPKKSTPK----------QTAAEHDSASASLSKSKQPASKKRKT 468
KK K K + K K++ K + AAE + + K K+ A KK+
Sbjct: 645 KIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCE 704
Query: 469 ENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
E K + +A+ +K+ ++ +K + K K K K AK
Sbjct: 705 EAAKKEK--EAAERKKCEELAKKIKKAAEKKKCKKLAK 740
Score = 95.5 bits (236), Expect = 3e-19
Identities = 130/511 (25%), Positives = 209/511 (40%), Gaps = 51/511 (9%)
Query: 31 KGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKG 90
K + E +EK+A + + K + E A K+K + ++ E+ KE E ++ K
Sbjct: 356 KKQKEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKAAKERKEAAEKKKC 415
Query: 91 EEEKDEEDEDGGEGEGE------GEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKET 144
EE +E E + E + E+++ +E + E EA E+ K + KK K+
Sbjct: 416 EEAAKKEKEAAERKKCEELAKNIKKAAEKKKCKEAAKKEKEAAERKKCEELAKK--IKKA 473
Query: 145 ASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAF 204
A +KK T + ERK E + K K EK E+ K A
Sbjct: 474 AEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIKKKCKKLAKKEKETAEK-KKCEKAAK 532
Query: 205 K----LSKRKPDDNLHALHSILFGKR-TKAYNLKRNIGQFSGFVWTENEEKQRAKVKERI 259
K K+K + K+ K+ ++ + E K+ A+ K+
Sbjct: 533 KRKEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCE 592
Query: 260 DKYVKEKLV---DFCDVLNIPVSKGNIKK--EELSVKLLEFLENPQATTDVLLADNEKKV 314
+ KEK V C+ L + K KK +E + K E E + + KK+
Sbjct: 593 EAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAEREKC------GELAKKI 646
Query: 315 KKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVE---EDEKAELSDAKDESQ 371
KK K K A E ++KK ++ KKRK +++ + E K E A+ +
Sbjct: 647 KKAAEK---KKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKEAAEKKKC 703
Query: 372 ENVAAPHKESDDDESKSEE--EEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSS 429
E A KE+ + K EE ++ K A+KK KK+ K+ KAGE+ K K
Sbjct: 704 EEAAKKEKEA-AERKKCEELAKKIKKAAEKKKCKKLAKK---KKAGEKNKLKKGNKKGKK 759
Query: 430 KNVDKTPKKSTPKQTAAEHDSASASLSKSKQPA--------SKKRKTENEK------PDT 475
+K + K+ AAE + K K+ A +KKRK E EK
Sbjct: 760 ALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKK 819
Query: 476 KGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
+ +A+ KK+ +K++K ++ K K K AK
Sbjct: 820 RKEAAEKKKCEKAAKKRKEEAEKKKCEKTAK 850
Score = 92.4 bits (228), Expect = 3e-18
Identities = 114/495 (23%), Positives = 203/495 (40%), Gaps = 54/495 (10%)
Query: 33 EAEAEEKEAAPQEDEDASAEAVKSEAEN--AEEKDKGGDQVEEKEEVEKETDEVKDEV-- 88
EA +EKEAA ++ + +A+ K EAE E+ K + EK++ EK + K+E
Sbjct: 783 EAAKKEKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEK 842
Query: 89 -------KGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGK 141
K +E E+ + + + E+++ E+ + EA EK K KK +
Sbjct: 843 KKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKK--E 900
Query: 142 KETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPN 201
KE A +KK E+ ERK E + + K K EK GE+ K
Sbjct: 901 KELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNK---- 956
Query: 202 VAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDK 261
K+K + GK++K K+ + + E E + K +ER K
Sbjct: 957 -----LKKKAGKGKKKCKKL--GKKSKRAAEKKKCAEAAK---KEKEAATKKKCEERAKK 1006
Query: 262 YVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA---TTDVLLADNEKKVKKRT 318
+ C EE + KL E E Q + A +K+ ++R
Sbjct: 1007 QKEAAEKKQC--------------EERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERA 1052
Query: 319 RKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPH 378
+K+ ++ + E AKK K+ +E KK+ +E E AE ++ +++ A
Sbjct: 1053 KKL--KEAAEQKQCEERAKKLKEAAE--KKQCEERAKKEKEAAEKKQCEERAKKLKEAAE 1108
Query: 379 KESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKK 438
K+ ++ +K E+E + K ++ +K+ + K E K K+ K K +
Sbjct: 1109 KKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKKEKEATEK-----QKCAEA 1163
Query: 439 STPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSK-KQTDKSSKALVKDQG 497
+ ++ AAE + + + K+ A KK+ + K + + K ++ K K + Q
Sbjct: 1164 AKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEPAEMKKCEEAAKKEKEAAEKQK 1223
Query: 498 KSKSGKKAKAVPSRE 512
+K+ KK K ++
Sbjct: 1224 CAKAAKKEKEAAEKK 1238
Score = 89.0 bits (219), Expect = 3e-17
Identities = 115/524 (21%), Positives = 202/524 (37%), Gaps = 58/524 (11%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQ 70
K + E + A E K EA EK+ + + A K + E + +K K +
Sbjct: 512 KKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAE 571
Query: 71 VEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEG------EGEEEEEQEEEEEAEA 124
++ E+ KE E ++ K EE +E E + E + E+++ +E + E
Sbjct: 572 KKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKEAAKKEK 631
Query: 125 EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGK 184
EA E+ K KK K+ A +KK E+ T E+K E+ + + K +
Sbjct: 632 EAAEREKCGELAKK--IKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAE 689
Query: 185 GLVIEKGRGEQLK--DIPNVAFKLSKRKPDDNL-HALHSILFGKRTKAYNLKRNIGQFSG 241
EK E+ K + + ++RK + L + K+ K K+ G+ +
Sbjct: 690 AAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNK 749
Query: 242 FVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA 301
+ K+ K K++ + K+K + K +E + K E E +
Sbjct: 750 LKKGNKKGKKALKEKKKCRELAKKKAAE------------KKKCKEAAKKEKEAAEKKKC 797
Query: 302 TTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKA 361
EK KKR + K A A ++KK ++ KKRK E+A
Sbjct: 798 ---------EKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRK--------EEA 840
Query: 362 ELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSA 421
E + +++ K+ + +K ++ + K +K +KK + K E K
Sbjct: 841 EKKKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKE 900
Query: 422 KKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKR-------------KT 468
K+ K K ++ KK ++ AE K K+ A KK+ K
Sbjct: 901 KELAEK--KKCEEAAKK---EKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKN 955
Query: 469 ENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSRE 512
+ +K KGK KK KS +A K + + K+ +A ++
Sbjct: 956 KLKKKAGKGKKKCKKLGKKSKRAAEKKKCAEAAKKEKEAATKKK 999
Score = 87.4 bits (215), Expect = 9e-17
Identities = 123/534 (23%), Positives = 226/534 (42%), Gaps = 72/534 (13%)
Query: 20 DAAPNNQETEVKG---EAEAEEKEAAPQEDEDASAEAVKSEAEN-----------AEEKD 65
+AA +E K EA +EKEAA ++ + A+ +K AE A EK+
Sbjct: 689 EAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKN 748
Query: 66 K-------GGDQVEEKEEVEK-------ETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGE 111
K G ++EK++ + E + K+ K E+E E+ + + E
Sbjct: 749 KLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAAEKKKCEKTAKKRKEEA 808
Query: 112 EEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSV 171
E+++ E+ + EA EK K ++ KK +KE A +KK T + T E+K E+ +
Sbjct: 809 EKKKCEKTAKKRKEAAEKKKCEKAAKK--RKEEAEKKKCEKTAKKRKETAEKKKCEKAAK 866
Query: 172 PSPSKSAKSSGGKGLVIEKGRGEQLK--DIPNVAFKLSKRKPDDNLHALHSILFGKRTKA 229
+ K K K E+ K + +L+++K + A +R K
Sbjct: 867 KRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEA-AKKEKEVAERKKC 925
Query: 230 YNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELS 289
L + I + + EK++ K + +K EK + L KG K ++L
Sbjct: 926 EELAKKIKKAA--------EKKKCKKLAKKEKKAGEK-----NKLKKKAGKGKKKCKKLG 972
Query: 290 VKLLEFLENP---QATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKK------QK 340
K E +A A +KK ++R +K ++ + E AKK QK
Sbjct: 973 KKSKRAAEKKKCAEAAKKEKEAATKKKCEERAKK--QKEAAEKKQCEERAKKLKEAAEQK 1030
Query: 341 KTSESGKKRKGSSDVEEDEK--------AELSDAKDESQENVAAPHKESDDDESKSEEEE 392
+ E KK K +++ ++ E+ AE ++ +++ A K+ ++ +K E+E
Sbjct: 1031 QCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEA 1090
Query: 393 DKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSAS 452
+ K ++ +KK+ + + ER K K+ K K ++ K+ ++ AAE +
Sbjct: 1091 AEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEK--KRCEEAAKR---EKEAAEKKKCA 1145
Query: 453 ASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
+ K K+ K++ E K + +A+ KK+ +++K + K K AK
Sbjct: 1146 EAAKKEKEATEKQKCAEAAKKEK--EAAEKKKCAEAAKREKEAAQKKKCADLAK 1197
Score = 79.3 bits (194), Expect = 3e-14
Identities = 112/464 (24%), Positives = 188/464 (40%), Gaps = 68/464 (14%)
Query: 20 DAAPNNQETEVKGEAEA---EEKEAAPQEDEDASAEAVKSEAEN--AEEKDKGGDQVEEK 74
+AA +E K + E ++KEAA ++ + A+ +K AE EE+ K + EK
Sbjct: 986 EAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEK 1045
Query: 75 EEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKR 134
++ E+ ++K+ E+++ EE + E E+++ EE + E EA EK + +
Sbjct: 1046 KQCEERAKKLKEAA--EQKQCEE-----RAKKLKEAAEKKQCEERAKKEKEAAEKKQCEE 1098
Query: 135 GPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGE 194
KK KE A +K+ ER +E++ E+ +K K + K E + E
Sbjct: 1099 RAKK--LKEAAEKKQ-----CEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKKE 1151
Query: 195 QLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAK 254
+ + +K++ + K+ A KR EK+ A+
Sbjct: 1152 KEATEKQKCAEAAKKEKE---------AAEKKKCAEAAKR--------------EKEAAQ 1188
Query: 255 VKERIDKYVKEKLVDFCDVLNIPVSKGNIKK-EELSVKLLEFLENPQATTDVLLADNEKK 313
K+ D KE+ +KK EE + K E E + K
Sbjct: 1189 KKKCADLAKKEQ------------EPAEMKKCEEAAKKEKEAAEKQKCA---------KA 1227
Query: 314 VKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQEN 373
KK K A E A ++KK +E+ KK K + + EKAE + A
Sbjct: 1228 AKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEAAKKEKEAEKKRKCEKAEKAAALKRQCAK 1287
Query: 374 VAAPHKESD-DDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNV 432
+ KE+ + ++ K A+KK +K+ K+ +A E K AK K
Sbjct: 1288 LVIRAKEAALRKKCAIIAKKAKMAAEKKECEKLAKKAK--EAIEWKKCAKLAKKKREAEK 1345
Query: 433 DKTPKKSTPKQTAAEHDSASASLSKSKQPASKKR-KTENEKPDT 475
K K + ++ AAE L+K+K+ KK+ + EN K T
Sbjct: 1346 KKCAKLAKKEKEAAEKKKRCKDLAKNKKKGHKKKGRNENRKKRT 1389
Score = 72.4 bits (176), Expect = 3e-12
Identities = 110/502 (21%), Positives = 201/502 (39%), Gaps = 39/502 (7%)
Query: 19 DDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVE 78
+ AA ++ K + E K+ ++ AEA K E E AE+K +EKE E
Sbjct: 862 EKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKELAEKKKCEEAAKKEKEVAE 921
Query: 79 -KETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPK 137
K+ +E+ ++K EK + + + + GE + +++ + + + + K K+KR +
Sbjct: 922 RKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGK-KSKRAAE 980
Query: 138 KGGKKETASEKKDPATP--ASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQ 195
K E A ++K+ AT ER ++++ E+ +K K + + E R ++
Sbjct: 981 KKKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKEAAEQKQCEE--RAKK 1038
Query: 196 LKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKV 255
LK+ K + + A +R K Q E E ++ +
Sbjct: 1039 LKEAAEK--KQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKQC 1096
Query: 256 KERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFL--ENPQATTDVLLADNEKK 313
+ER K + C+ + +KE K E +A A+ KK
Sbjct: 1097 EERAKKLKEAAEKKQCE------ERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAEAAKK 1150
Query: 314 VKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQEN 373
K+ T K K A E A ++KK +E+ K+ K E +K + +D + QE
Sbjct: 1151 EKEATEK---QKCAEAAKKEKEAAEKKKCAEAAKREK-----EAAQKKKCADLAKKEQEP 1202
Query: 374 VAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKT--------P 425
+ ++ +K E+E + + K +KK + K E K ++
Sbjct: 1203 A---EMKKCEEAAKKEKEAAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEA 1259
Query: 426 VKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGK-ASSKKQ 484
K K +K K ++ AA + + ++K+ A +K+ K K K A+ KK+
Sbjct: 1260 AKKEKEAEKKRKCEKAEKAAALKRQCAKLVIRAKEAALRKKCAIIAK---KAKMAAEKKE 1316
Query: 485 TDKSSKALVKDQGKSKSGKKAK 506
+K +K + K K AK
Sbjct: 1317 CEKLAKKAKEAIEWKKCAKLAK 1338
Score = 65.5 bits (158), Expect = 4e-10
Identities = 114/503 (22%), Positives = 209/503 (40%), Gaps = 69/503 (13%)
Query: 39 KEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEED 98
K + + +A K+ A+ ++K K +Q + +E ++E +V+ V EE + +
Sbjct: 48 KNESTDDSNQIRCDADKTAADKKKQKQKEEEQAKIRE-YKRECLKVQKRVLAEEIRCSGE 106
Query: 99 EDGGEGEGEGEGEEEEEQE---EEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPA 155
+D +G + + ++ + +A+ AD+++ + A KKD
Sbjct: 107 KDRILIQGMMKCLTDGMKKACTKIAKAKLIADKELAVQCA---------ALSKKDKVKAL 157
Query: 156 SERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIP--NVAFKLSKRKPDD 213
++ RE+ + + SP++ K KG K G K N A K K +
Sbjct: 158 LKKCEREKSKEKECNQNSPAEGDKDRTKKGKTKGKSGGGNKKRSTKENRAKKGKKLVKNR 217
Query: 214 NLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRA--------KVKERIDKYVKE 265
L + + ++N +TE+E K+ A K+K K V
Sbjct: 218 FTQKLEHCIKSEWADVCECRQN--------FTEDERKRLAASYKCMGTKIKSICRKRV-- 267
Query: 266 KLVDFCDVLNI-----PVSKGNIKK--EELSVKLLEFLENPQATTDVLLADNEKKVKKRT 318
+ + C+ P KG KK E+ +L + QA + + K+VKK+
Sbjct: 268 -IAEMCEAAGYVKSSEPKKKGKKKKNDEKKEKELEREILKEQAEEEAKIRGVVKEVKKKC 326
Query: 319 RKVTPSKSPGEASTETPAKKQKKTSES-GKKRKGSSDVEEDEKA---ELSDAKDESQENV 374
++ K + + + +KK + KK+K EEDEK EL+ K E+ E
Sbjct: 327 KEKALKKKCKDLGRKMKEEAEKKKCAALAKKQK-----EEDEKKACKELAKKKKEADEK- 380
Query: 375 AAPHKESDDDESKSEEEEDKSKAQK--KTSKKIVKEGSGSKAGERTKSA--KKTPVKSSK 430
K+ ++ +K ++ +K K +K K K+ ++ +A ++ K A +K + +K
Sbjct: 381 ----KKCEEAANKEKKAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEAAERKKCEELAK 436
Query: 431 NVDKTPKKSTPKQTA------AEHDSASASLSKSKQPASKKRKTENEKPDTKGK-ASSKK 483
N+ K +K K+ A AE K K+ A KK+ E K KGK + +K
Sbjct: 437 NIKKAAEKKKCKEAAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAK---KGKEVAERK 493
Query: 484 QTDKSSKALVKDQGKSKSGKKAK 506
+ ++ +K + K + K K K AK
Sbjct: 494 KCEELAKKIKKAEIKKKCKKLAK 516
Score = 63.9 bits (154), Expect = 1e-09
Identities = 115/537 (21%), Positives = 199/537 (36%), Gaps = 101/537 (18%)
Query: 25 NQETEVKGEAEAEEKEAAPQED--EDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETD 82
+++ +VK + E+E + +++ +++ AE K + + K K G +++ E
Sbjct: 149 SKKDKVKALLKKCEREKSKEKECNQNSPAEGDKDRTKKGKTKGKSGGGNKKRSTKENRAK 208
Query: 83 EVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEA------------------ 124
+ K VK + E E E + ++E + A
Sbjct: 209 KGKKLVKNRFTQKLEHCIKSEWADVCECRQNFTEDERKRLAASYKCMGTKIKSICRKRVI 268
Query: 125 ----EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKS 180
EA VK+ PKK GKK+ EKK+ ER + + E + K K
Sbjct: 269 AEMCEAAGYVKSSE-PKKKGKKKKNDEKKEKEL---EREILKEQAEEEAKIRGVVKEVKK 324
Query: 181 SGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFS 240
EK ++ KD+ RK + K+ K
Sbjct: 325 K-----CKEKALKKKCKDLG--------RKMKEEAEKKKCAALAKKQK------------ 359
Query: 241 GFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQ 300
E +EK+ K + K EK K EE + K + E +
Sbjct: 360 -----EEDEKKACKELAKKKKEADEKK----------------KCEEAANKEKKAAEKKK 398
Query: 301 ATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSD------ 354
EK K+R K A E A ++KK E K K +++
Sbjct: 399 C---------EKAAKERKEAAEKKKCEEAAKKEKEAAERKKCEELAKNIKKAAEKKKCKE 449
Query: 355 --VEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGS 412
+E E AE ++ +++ A K+ ++ +K +E + K ++ +KKI K
Sbjct: 450 AAKKEKEAAERKKCEELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIKKAEIKK 509
Query: 413 KAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEK 472
K + K K+T K K +K KK ++ AAE + K K+ A KK+ ++ K
Sbjct: 510 KCKKLAKKEKETAEK--KKCEKAAKK---RKEAAEKKKCEKAAKKRKEAAEKKKCEKSAK 564
Query: 473 PDTKGKASSKKQTDKSSKALVKDQGKSK---SGKKAKAVPSREAMHAVVVDILKEVD 526
+ +A+ KK+ +K++K + K K + KK K V R+ + I K +
Sbjct: 565 --KRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAE 619
Score = 60.5 bits (145), Expect = 1e-08
Identities = 88/391 (22%), Positives = 153/391 (38%), Gaps = 33/391 (8%)
Query: 15 QAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEK 74
Q + ++ A +E K + E K+ ++ E K E AE+K +EK
Sbjct: 1029 QKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEERAKKLKEAAEKKQCEERAKKEK 1088
Query: 75 EEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKR 134
E EK+ + ++ K +E E+ + + E E E++ EE + E EA EK K
Sbjct: 1089 EAAEKK--QCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKKKCAE 1146
Query: 135 GPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGE 194
KK +KE ++K +E +E++ E+ +K K + K + + E
Sbjct: 1147 AAKK--EKEATEKQK-----CAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKE 1199
Query: 195 QLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAK 254
Q + +K++ + + K KA ++ + +E++ A+
Sbjct: 1200 QEPAEMKKCEEAAKKEKE-------AAEKQKCAKAAKKEKEAAEKKKCAEAAKKEQEAAE 1252
Query: 255 VKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKV 314
K+ + KEK + K +K E + L Q V+ A
Sbjct: 1253 KKKCAEAAKKEKEAE---------KKRKCEKAEKAAAL-----KRQCAKLVIRAKEAALR 1298
Query: 315 KKRTRKVTPSKSPGE-ASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQEN 373
KK +K E E AKK K+ E K K + E EK + AK +E
Sbjct: 1299 KKCAIIAKKAKMAAEKKECEKLAKKAKEAIEWKKCAKLAKKKREAEKKKC--AKLAKKEK 1356
Query: 374 VAAPHKESDDDESKSEEEEDKSKAQKKTSKK 404
AA K+ D +K++++ K K + + KK
Sbjct: 1357 EAAEKKKRCKDLAKNKKKGHKKKGRNENRKK 1387
>NFM_MOUSE (P08553) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M)
Length = 848
Score = 101 bits (252), Expect = 5e-21
Identities = 114/418 (27%), Positives = 180/418 (42%), Gaps = 81/418 (19%)
Query: 26 QETEVKGE-AEAEEKEAAPQEDEDASAEAVKSEAENAEEKD-------KGGDQVEEKEEV 77
+ET+V+ E +E EE A E+ ASA+ K EAE EE+ K + EE+EE
Sbjct: 457 EETKVEDEKSEMEETLTAIAEELAASAKEEKEEAEEKEEEPEAEKSPVKSPEAKEEEEEG 516
Query: 78 EKETDEVKDEVKGEEEK----DEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEAD-EKVKA 132
EKE +E E + EE++ D+ +E G E EG E +E E++EEE E EAE + E+ +A
Sbjct: 517 EKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQEEEEGETEAEGEGEEAEA 576
Query: 133 KRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGR 192
K K GK E + K++ E+P + + + + V ++ GKG E+ +
Sbjct: 577 KEEKKIEGKVEEVAVKEEIKV---EKPEKAKSPMPKSPVEEVKPKPEAKAGKGEQKEEEK 633
Query: 193 GEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQR 252
E+ K +++K P + E EK+
Sbjct: 634 VEEEKK------EVTKESPKE--------------------------------EKVEKKE 655
Query: 253 AKVKERIDKY-----VKEKLVDFCDVLNIPVS-KGNIKKEELSVKLLEFLENPQATTDVL 306
K K+ DK VKEK V+ +V+ I S K +++K+ E PQ
Sbjct: 656 EKPKDVADKKKAESPVKEKAVE--EVITISKSVKVSLEKDTKE-------EKPQP----- 701
Query: 307 LADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDA 366
++KVK++ + S+ E S +P + +K+ + +G + EE E E
Sbjct: 702 ----QEKVKEKAEEEGGSEE--EGSDRSPQESKKEDIAINGEVEGKEE-EEQETQEKGSG 754
Query: 367 KDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKT 424
++E + V S +E K E+ D K +KI EG TKS T
Sbjct: 755 REEEKGVVTNGLDVSPAEEKKGEDSSDDKVVVTKKVEKITSEGGDGATKYITKSVTVT 812
Score = 92.8 bits (229), Expect = 2e-18
Identities = 122/473 (25%), Positives = 194/473 (40%), Gaps = 89/473 (18%)
Query: 29 EVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEV 88
E+ E + E++++ +E A AE + + A+ EEK EE EE E+E + K V
Sbjct: 454 EIIEETKVEDEKSEMEETLTAIAEELAASAK--EEK-------EEAEEKEEEPEAEKSPV 504
Query: 89 KGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEK 148
K E K+EE+E GE+EEE+E +EE E E DE VK+ + + G +KE +SEK
Sbjct: 505 KSPEAKEEEEE----------GEKEEEEEGQEE-EEEEDEGVKSDQAEEGGSEKEGSSEK 553
Query: 149 KDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLK-DIPNVAFKLS 207
+ E T E + +K K GK V E E++K + P A
Sbjct: 554 DEGEQEEEEGETE----AEGEGEEAEAKEEKKIEGK--VEEVAVKEEIKVEKPEKAKSPM 607
Query: 208 KRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKL 267
+ P + + GK E+K+ KV+E + KE
Sbjct: 608 PKSPVEEVKPKPEAKAGK---------------------GEQKEEEKVEEEKKEVTKES- 645
Query: 268 VDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSP 327
P + KKE E P+ D A++ K K +T SKS
Sbjct: 646 ---------PKEEKVEKKE----------EKPKDVADKKKAESPVKEKAVEEVITISKSV 686
Query: 328 GEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESK 387
+ S E K++K + K K + +E+ ++ +E++A + + E K
Sbjct: 687 -KVSLEKDTKEEKPQPQEKVKEKAEEEGGSEEEGSDRSPQESKKEDIAI----NGEVEGK 741
Query: 388 SEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTP-----KKSTPK 442
EEE++ Q+K S G + G T +P + K D + K K
Sbjct: 742 EEEEQE---TQEKGS------GREEEKGVVTNGLDVSPAEEKKGEDSSDDKVVVTKKVEK 792
Query: 443 QTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKD 495
T+ D A+ ++KS K E+E+ + S+KK +S A+VK+
Sbjct: 793 ITSEGGDGATKYITKSVTVTQKVE--EHEETFEEKLVSTKKVEKVTSHAIVKE 843
Score = 61.6 bits (148), Expect = 6e-09
Identities = 125/644 (19%), Positives = 243/644 (37%), Gaps = 103/644 (15%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA 61
AT + +H K VQ + D + E ++ E E+EA ++D +A+ A++ + E +
Sbjct: 157 ATLEMVNHEKAQVQLDSD-----HLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEES 211
Query: 62 EEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQ----- 116
K E++K+ ++DEV EE+ + + E +
Sbjct: 212 SMV---------KVELDKKVQSLQDEVAFLRRNHEEEVADLLAQIQASHITVERKDYLKT 262
Query: 117 -------EEEEEAEAEADEKV-KAKRGPKKGGKK--ETASEKKDPATPASERPTRERKTV 166
E + E +D+ + +A+ K K E A + K+ A E R+ +
Sbjct: 263 DISTALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQL 322
Query: 167 ERYSVPSPS-KSAKSSGGKGLV-IEKGRGEQLKDIPNVAFKLS----------------- 207
+ S+ S + K S + L IE+ L + +L
Sbjct: 323 QSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREY 382
Query: 208 ------KRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDK 261
K D + A +L G+ T+ G +G ++T + K + K
Sbjct: 383 QDLLNVKMALDIEIAAYRKLLEGEETRFSTFS---GSITGPLYTHRQPSVTISSKIQKTK 439
Query: 262 YVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKV 321
KL + + + ++ E+ ++ E A + L A +++
Sbjct: 440 VEAPKLKVQHKFVEEIIEETKVEDEKSEME-----ETLTAIAEELAASAKEE-------- 486
Query: 322 TPSKSPGEASTETP--------AKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQEN 373
K E E P + + K+ E G+K + EE+E+ + D+++E
Sbjct: 487 ---KEEAEEKEEEPEAEKSPVKSPEAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEG 543
Query: 374 VAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTK---SAKKTPVKSSK 430
+ S+ DE + EEEE +++A+ EG ++A E K ++ VK
Sbjct: 544 GSEKEGSSEKDEGEQEEEEGETEAE--------GEGEEAEAKEEKKIEGKVEEVAVKEEI 595
Query: 431 NVDKTPKKSTP-KQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSS 489
V+K K +P ++ E K ++ K E EK + ++ +++ +K
Sbjct: 596 KVEKPEKAKSPMPKSPVEEVKPKPEAKAGKGEQKEEEKVEEEKKEVTKESPKEEKVEKKE 655
Query: 490 KAL--VKDQGKSKSGKKAKAVP-----SREAMHAVVVDILKEVDFNTATLSDILRQLG-- 540
+ V D+ K++S K KAV S+ ++ D +E + + + G
Sbjct: 656 EKPKDVADKKKAESPVKEKAVEEVITISKSVKVSLEKDTKEEKPQPQEKVKEKAEEEGGS 715
Query: 541 THFGVDLMHRKAEVKDI-ITDVINNMSDEEDEGEEADGDGDADK 583
G D ++++ +DI I + +EE E +E + +K
Sbjct: 716 EEEGSDRSPQESKKEDIAINGEVEGKEEEEQETQEKGSGREEEK 759
Score = 54.7 bits (130), Expect = 7e-07
Identities = 57/269 (21%), Positives = 115/269 (42%), Gaps = 23/269 (8%)
Query: 246 ENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDV 305
E +E++ KE ++ +E+ + V + +G +KE S K E + T+
Sbjct: 508 EAKEEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQEEEEGETEA 567
Query: 306 ------LLADNEKKVKKRTRKVTPSKS-----PGEASTETPAKKQKKTSESGKKRKGSSD 354
A EKK++ + +V + P +A + P ++ + + G +
Sbjct: 568 EGEGEEAEAKEEKKIEGKVEEVAVKEEIKVEKPEKAKSPMPKSPVEEVKPKPEAKAGKGE 627
Query: 355 VEEDEKAELSDAKDESQENVAAPHKESDDDES-KSEEEEDKSKAQKKTSKKIVKEGSGSK 413
+E+EK E E ++ V KES +E + +EE+ K A KK ++ VKE + +
Sbjct: 628 QKEEEKVE------EEKKEVT---KESPKEEKVEKKEEKPKDVADKKKAESPVKEKAVEE 678
Query: 414 AGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKP 473
+KS K + K +K P++ ++ AE + S + P K++
Sbjct: 679 VITISKSVKVSLEKDTKEEKPQPQEKVKEK--AEEEGGSEEEGSDRSPQESKKEDIAING 736
Query: 474 DTKGKASSKKQTDKSSKALVKDQGKSKSG 502
+ +GK +++T + +++G +G
Sbjct: 737 EVEGKEEEEQETQEKGSGREEEKGVVTNG 765
>CALD_CHICK (P12957) Caldesmon (CDM)
Length = 771
Score = 99.0 bits (245), Expect = 3e-20
Identities = 111/455 (24%), Positives = 196/455 (42%), Gaps = 68/455 (14%)
Query: 25 NQETEVKGEAEAEEK--EAAPQEDEDASAEAVKSEAENAE----EKDKGGDQVEEKEEVE 78
N E + E E+ +AA +E E+A E K EAE E E++K + ++K E E
Sbjct: 222 NAENDTNAMLEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEE 281
Query: 79 KETDEVKDEVKGEEEKDE-EDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPK 137
K+ E ++ K EEEK E+ + + E E + EE E+ + EE A+E+ KA+ +
Sbjct: 282 KKAAEERERAKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKAAEERAKAEE-ER 340
Query: 138 KGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLK 197
K ++ +E++ A + +ERK E + AK+ K EK R E
Sbjct: 341 KAAEERAKAEEERKAAEERAKAEKERKAAEE------RERAKAEEEKRAAEEKARLE--- 391
Query: 198 DIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKE 257
A KL ++K + K+ + + N+ + EE + AKV+
Sbjct: 392 -----AEKLKEKKKMEE----------KKAQEEKAQANL-------LRKQEEDKEAKVEA 429
Query: 258 RIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKR 317
+ + + EKL P SK + K+ + + P+ + K V R
Sbjct: 430 KKES-LPEKLQ--------PTSKKDQVKDNKDKE-----KAPK--------EEMKSVWDR 467
Query: 318 TRKVTPSKSP-GEASTETPAKKQKKTSESGKKRKGSSDVE------EDEKAELSDAKDES 370
R V K+ GE TP K + + KG+++ E ++++ E + DE
Sbjct: 468 KRGVPEQKAQNGERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQQEAAVELDEL 527
Query: 371 QENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSK 430
++ K +++E K ++EE + K +++ KK +KE + E + +K P
Sbjct: 528 KKRREERRKILEEEEQKKKQEEAERKIREEEEKKRMKEEIERRRAEAAEKRQKVPEDGVS 587
Query: 431 NVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKK 465
K K +PK ++ + + + L+KS Q + K
Sbjct: 588 EEKKPFKCFSPKGSSLKIEERAEFLNKSAQKSGMK 622
Score = 79.0 bits (193), Expect = 3e-14
Identities = 109/499 (21%), Positives = 206/499 (40%), Gaps = 74/499 (14%)
Query: 69 DQVEEKEEVEKETDE---VKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAE 125
D E + E+ ++ E ++ E + D+++E+ +E Q+EE + E
Sbjct: 2 DDFERRRELRRQKREEMRLEAERLSYQRNDDDEEEAARERRRRARQERLRQKEEGDVSGE 61
Query: 126 ADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVP-SPSKSAKSSGGK 184
EK + ++ET D A RE + +R K +
Sbjct: 62 VTEKSEVN-AQNSVAEEETKRSTDDEAALLERLARREERRQKRLQEALERQKEFDPTITD 120
Query: 185 GLVIEKGRGE----QLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFS 240
G + R E + +I K+ R+ + ++ TK+Y +RN +
Sbjct: 121 GSLSVPSRREVNNVEENEITGKEEKVETRQGRCEIEETETV-----TKSY--QRNNWRQD 173
Query: 241 GFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLE------ 294
G + EEK + K + + +E VD + V K K+E + K L
Sbjct: 174 GEEEGKKEEKDSEEEKPK-EVPTEENQVD------VAVEKSTDKEEVVETKTLAVNAEND 226
Query: 295 ---FLENPQATTDV----------------------LLADNEKKVKKRTRKVTPSKSPGE 329
LE Q+ TD L A+ EKK + +K K E
Sbjct: 227 TNAMLEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAE 286
Query: 330 ASTETPAKKQKKTSESGKKRKGSSD---VEEDEKAELSDAKDESQENVAAPH-KESDDDE 385
A+++K+ +E ++ K + EE E+A+ + + ++E A +++ ++
Sbjct: 287 ERERAKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKAAEERAKAEEERKAAEER 346
Query: 386 SKSEEE----EDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTP 441
+K+EEE E+++KA+K+ +K +E +KA E ++A++ K+ +K +K
Sbjct: 347 AKAEEERKAAEERAKAEKE--RKAAEERERAKAEEEKRAAEE---KARLEAEKLKEKKKM 401
Query: 442 KQTAAEHDSASASLSKSKQPASKKRKTENEK---PDTKGKASSKKQT--DKSSKALVKDQ 496
++ A+ + A A+L + KQ K+ K E +K P+ S K Q +K + K++
Sbjct: 402 EEKKAQEEKAQANLLR-KQEEDKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEE 460
Query: 497 GKSKSGKKAKAVPSREAMH 515
KS +K + VP ++A +
Sbjct: 461 MKSVWDRK-RGVPEQKAQN 478
Score = 73.6 bits (179), Expect = 1e-12
Identities = 112/518 (21%), Positives = 208/518 (39%), Gaps = 82/518 (15%)
Query: 33 EAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEE 92
EA +KE P + + + + E N EE + G EEK E + E+++ E
Sbjct: 106 EALERQKEFDPTITDGSLSVPSRREVNNVEENEITGK--EEKVETRQGRCEIEET---ET 160
Query: 93 EKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPA 152
+ +GE EG++EE+ EEE+ + E+ + +K KE E K A
Sbjct: 161 VTKSYQRNNWRQDGEEEGKKEEKDSEEEKPKEVPTEENQVDVAVEKSTDKEEVVETKTLA 220
Query: 153 TPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPD 212
A E T E+ + K + + + +E E+LK K+K +
Sbjct: 221 VNA-ENDTNAMLEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAE 279
Query: 213 DNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCD 272
+ A +R KA KR EE++RAK +E K +E+
Sbjct: 280 EEKKAAEE---RERAKAEEEKRAA-----------EERERAKAEEE-RKAAEER------ 318
Query: 273 VLNIPVSKGNIKKEELSVK-LLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEAS 331
+ ++E + + + E +A + A+ E+K + K + E
Sbjct: 319 ------ERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAEKERKAAEER 372
Query: 332 TETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDE-SQENVAAPHKESDDDESKSE- 389
A+++K+ +E K R + ++E +K E A++E +Q N+ K+ +D E+K E
Sbjct: 373 ERAKAEEEKRAAEE-KARLEAEKLKEKKKMEEKKAQEEKAQANLL--RKQEEDKEAKVEA 429
Query: 390 -------------------EEEDKSKAQKKTSKKIVKEGSG-----SKAGERTKSAKK-- 423
+ +DK KA K+ K + G ++ GER + K
Sbjct: 430 KKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMKSVWDRKRGVPEQKAQNGERELTTPKLK 489
Query: 424 --------TPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRK-TENEKPD 474
+ +K + N + +K KQ A+ L + K+ ++RK E E+
Sbjct: 490 STENAFGRSNLKGAANAEAGSEKLKEKQ-----QEAAVELDELKKRREERRKILEEEEQK 544
Query: 475 TKGKASSKKQTDKSSKALVKDQ---GKSKSGKKAKAVP 509
K + + +K ++ K +K++ ++++ +K + VP
Sbjct: 545 KKQEEAERKIREEEEKKRMKEEIERRRAEAAEKRQKVP 582
Score = 66.2 bits (160), Expect = 2e-10
Identities = 104/456 (22%), Positives = 182/456 (39%), Gaps = 81/456 (17%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDK 66
E+ K + E A + E + A+AEE+ A +E E A AE + AE + ++
Sbjct: 279 EEEKKAAEERERAKAEEEKRAAEERERAKAEEERKAAEERERAKAEEERKAAEERAKAEE 338
Query: 67 GGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEA 126
EE+ + E+E ++ K EK+ + + E E EEE++ EE+A EA
Sbjct: 339 ERKAAEERAKAEEERKAAEERAKA--EKERKAAE----ERERAKAEEEKRAAEEKARLEA 392
Query: 127 DEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGL 186
EK+K K KK +K+ EK + +E K VE P K +S
Sbjct: 393 -EKLKEK---KKMEEKKAQEEKAQANLLRKQEEDKEAK-VEAKKESLPEKLQPTS----- 442
Query: 187 VIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE 246
+ +Q+KD K ++ P + + ++ ++ KR +
Sbjct: 443 -----KKDQVKD-----NKDKEKAPKEEMKSV-----------WDRKRGV---------- 471
Query: 247 NEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVL 306
+Q+A+ ER + KL + KG E S KL E + +A ++
Sbjct: 472 --PEQKAQNGER--ELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKE--KQQEAAVEL- 524
Query: 307 LADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDA 366
D KK ++ RK+ + +++KK E+ +K + EE+EK + +
Sbjct: 525 --DELKKRREERRKILEEE-----------EQKKKQEEAERKIR-----EEEEKKRMKEE 566
Query: 367 KDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPV 426
+ + A E + + ED +KK K +GS K ER + K+
Sbjct: 567 IERRRAEAA---------EKRQKVPEDGVSEEKKPFKCFSPKGSSLKIEERAEFLNKSAQ 617
Query: 427 KSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPA 462
KS T + + E +++ +K+ +PA
Sbjct: 618 KSGMKPAHTTAVVSKIDSRLEQYTSAVVGNKAAKPA 653
Score = 43.1 bits (100), Expect = 0.002
Identities = 58/275 (21%), Positives = 103/275 (37%), Gaps = 61/275 (22%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA 61
A E + + E A + E + A+AEE++ A +E AE +K + +
Sbjct: 343 AEERAKAEEERKAAEERAKAEKERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKKME 402
Query: 62 EEK---DKGGDQVEEKEEVEKET---------------DEVKDEVKGEEEKD-------- 95
E+K +K + K+E +KE KD+VK ++K+
Sbjct: 403 EKKAQEEKAQANLLRKQEEDKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMK 462
Query: 96 ----------EEDEDGGE---------------------GEGEGEGEEEEEQEEEEEAEA 124
E+ GE G E E+ +E+++EA
Sbjct: 463 SVWDRKRGVPEQKAQNGERELTTPKLKSTENAFGRSNLKGAANAEAGSEKLKEKQQEAAV 522
Query: 125 EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGK 184
E DE K + +K ++E +K++ A ER RE + +R + A+++ +
Sbjct: 523 ELDELKKRREERRKILEEEEQKKKQEEA----ERKIREEEEKKRMKEEIERRRAEAAEKR 578
Query: 185 GLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALH 219
V E G E+ K + K S K ++ L+
Sbjct: 579 QKVPEDGVSEEKKPFKCFSPKGSSLKIEERAEFLN 613
>MLH_TETTH (P40631) Micronuclear linker histone polyprotein (MIC LH)
[Contains: Micronuclear linker histone-alpha;
Micronuclear linker histone-beta; Micronuclear linker
histone-delta; Micronuclear linker histone-gamma]
Length = 633
Score = 97.4 bits (241), Expect = 9e-20
Identities = 105/500 (21%), Positives = 184/500 (36%), Gaps = 44/500 (8%)
Query: 24 NNQETEVKGEAEAEEKEAAPQEDEDAS-AEAVKSEAENAEEKDKGGDQVEEKEEVEKETD 82
N + EVK +A +KE A E E A+ + K K + + ++
Sbjct: 136 NLPQKEVKVYEDAYQKEYAQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSRRSSSKGKSS 195
Query: 83 EVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKK 142
K K K D +G + + ++ + KA KG K
Sbjct: 196 VSKGRTKSTSSKRRADSSASQGRSQSSSSNRRKASSSKDQKGTRSSSRKASNS--KGRKN 253
Query: 143 ETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNV 202
T++++ ++ ++ +K+ S SK+ KSS KG RG + N
Sbjct: 254 STSNKRNSSSSSKRSSSSKNKKS-------SSSKNKKSSSSKGRKSSSSRGRKASSSKNR 306
Query: 203 AFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKY 262
SK + + S K K R G + ++ ++ +K +ER + +
Sbjct: 307 KSSKSKDRKSSSSKGRKSSSSSKSNK-----RKASSSRGRKSSSSKGRKSSKSQERKNSH 361
Query: 263 VKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVT 322
+ S + K++E S K +K+ K
Sbjct: 362 ADTSKQMEDEGQKRRQSSSSAKRDESSKK-----------------SRRNSMKEARTKKA 404
Query: 323 PSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESD 382
+KS +AS K K S+S K K SS + + S K + +N H+ +D
Sbjct: 405 NNKSASKASKSGSKSKGKSASKS--KGKSSSKGKNSKSRSASKPKSNAAQNSNNTHQTAD 462
Query: 383 DDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGE----------RTKSAKKTPVKSSKNV 432
E+ S + +++ +++ K +V E S SK+ R+KS K+ KS KN
Sbjct: 463 SSENASSTTQTRTRGRQREQKDMVNEKSNSKSSSKGKKNSKSNTRSKSKSKSASKSRKNA 522
Query: 433 DKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKAL 492
K+ K +T S S S SKS+ P K E + + + K++ +S A
Sbjct: 523 SKSKKDTTNHGRQTRSKSRSESKSKSEAPNKPSNKMEVIEQPKEESSDRKRRESRSQSAK 582
Query: 493 VKDQGKSKSGKKAKAVPSRE 512
KSK+ +K + + +
Sbjct: 583 KTSDKKSKNRSDSKKMTAED 602
Score = 64.7 bits (156), Expect = 7e-10
Identities = 91/406 (22%), Positives = 159/406 (38%), Gaps = 74/406 (18%)
Query: 233 KRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKL 292
K+ IG F F+ EN +K AK K+ + + + + + D N+P + + ++ +
Sbjct: 97 KKPIGSFFRFL-EENRQKYAAKHKDLTNAKILKIMSE--DFNNLPQKEVKVYEDAYQKEY 153
Query: 293 LEFLENPQATTDVLLADNEKKVKKR---TRKVTPSKSPGEASTE---------------- 333
++L + + +KK KR T K S S G++S
Sbjct: 154 AQYLVEFKKWNEKYGQAAQKKQTKRKNSTSKSRRSSSKGKSSVSKGRTKSTSSKRRADSS 213
Query: 334 ----------------TPAKKQKKTSESGKK---RKGSSDVEEDEKAELSDAK----DES 370
+ +K QK T S +K KG + +++ S +K ++
Sbjct: 214 ASQGRSQSSSSNRRKASSSKDQKGTRSSSRKASNSKGRKNSTSNKRNSSSSSKRSSSSKN 273
Query: 371 QENVAAPHKESDDDE-------------SKSEEEEDKSKAQKKTSKKIVKEGSGSKAGER 417
+++ ++ +K+S + S + KSK +K +S K K S SK+ +R
Sbjct: 274 KKSSSSKNKKSSSSKGRKSSSSRGRKASSSKNRKSSKSKDRKSSSSKGRKSSSSSKSNKR 333
Query: 418 -------TKSAKKTPVKSSKNVD-KTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTE 469
KS+ KSSK+ + K T KQ E S S +K+ S K+
Sbjct: 334 KASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRRQSSSSAKRDESSKKSRR 393
Query: 470 NEKPDTKGKASSKKQTDKSSKALVKDQGKS------KSGKKAKAVPSREAMHAVVVDILK 523
N + + K ++ K K+SK+ K +GKS KS K K SR A +
Sbjct: 394 NSMKEARTKKANNKSASKASKSGSKSKGKSASKSKGKSSSKGKNSKSRSA--SKPKSNAA 451
Query: 524 EVDFNTATLSDILRQLGTHFGVDLMHRKAEVKDIITDVINNMSDEE 569
+ NT +D + R+ E KD++ + N+ S +
Sbjct: 452 QNSNNTHQTADSSENASSTTQTRTRGRQREQKDMVNEKSNSKSSSK 497
>UN89_CAEEL (O01761) Muscle M-line assembly protein unc-89
(Uncoordinated protein 89)
Length = 6632
Score = 95.1 bits (235), Expect = 4e-19
Identities = 146/593 (24%), Positives = 228/593 (37%), Gaps = 116/593 (19%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEV----KGEAEAEEKEAAPQEDEDASAEAVKSEAE 59
E E+ P + G++ +++ K ++ A E+ +P + E + + K E
Sbjct: 1387 EKTEEKPASPTKKTGEEVKSPKEKSPASPTKKEKSPAAEEVKSPTKKEKSPSSPTKKEKS 1446
Query: 60 NAEEKDKGGDQVEEK---------EEVEKETDEVKDEVKGEEEKD-------------EE 97
+ K GD+V+EK E+ ++ ++VK VK E+ D E+
Sbjct: 1447 PSSPTKKTGDEVKEKSPPKSPTKKEKSPEKPEDVKSPVKKEKSPDATNIVEVSSETTIEK 1506
Query: 98 DEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPAT---- 153
E E E EE ++E+ + DEK K+ K +K E K P
Sbjct: 1507 TETTMTTEMTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKS 1566
Query: 154 -------PASERPTRERKTVERYSVPSPSKS--AKSSGGKGLVIEKGRGEQLKDIPNVAF 204
PAS PT++ K+ E+ + P+ KS K EK E+LK
Sbjct: 1567 PEKVEEKPAS--PTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPK---- 1620
Query: 205 KLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVK 264
+ S K DD + K+ K + S E+ + KE+ + V+
Sbjct: 1621 EKSPEKADD------------KPKSPTKKEKSPEKSA-----TEDVKSPTKKEKSPEKVE 1663
Query: 265 EKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPS 324
EK P S KKE +P TD +VK T+K
Sbjct: 1664 EK----------PTSP--TKKES----------SPTKKTD-------DEVKSPTKK---E 1691
Query: 325 KSPG--EASTETPAKKQKKTS----ESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPH 378
KSP E +P KK+K E K K S + +EK + K++S E AA
Sbjct: 1692 KSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEE 1751
Query: 379 KESDDDESKSEEE--EDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTP 436
+S + KS E+ E+K K+ K VK + + TK K K T
Sbjct: 1752 VKSPTKKEKSPEKSAEEKPKSPTKKESSPVKM-ADDEVKSPTKKEKSPEKVEEKPASPTK 1810
Query: 437 KKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQ 496
K+ TP+++AAE + K K P+S +KT +E +K K+ K + S K
Sbjct: 1811 KEKTPEKSAAE--ELKSPTKKEKSPSSPTKKTGDE---SKEKSPEKPEEKPKSPTPKKSP 1865
Query: 497 GKSKSGKKAKAVPSREAMHAVVVDILKEVDFNTATLSDILRQLGTHFGVDLMH 549
S KK+K S EA + +++ T +D+ HF V + H
Sbjct: 1866 PGSPKKKKSK---SPEAEKPPAPKLTRDLKLQTVNKTDL-----AHFEVVVEH 1910
Score = 92.0 bits (227), Expect = 4e-18
Identities = 142/567 (25%), Positives = 218/567 (38%), Gaps = 101/567 (17%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAP----QEDEDASAEAVKS---------- 56
K P + E A+P T+ GE KE +P ++++ +AE VKS
Sbjct: 1384 KSPEKTEEKPASP----TKKTGEEVKSPKEKSPASPTKKEKSPAAEEVKSPTKKEKSPSS 1439
Query: 57 ----EAENAEEKDKGGDQVEE---------KEEVEKETDEVKDEVKGEEEKD-------- 95
E + K GD+V+E KE+ ++ ++VK VK E+ D
Sbjct: 1440 PTKKEKSPSSPTKKTGDEVKEKSPPKSPTKKEKSPEKPEDVKSPVKKEKSPDATNIVEVS 1499
Query: 96 -----EEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKD 150
E+ E E E EE ++E+ + DEK K+ K +K E K
Sbjct: 1500 SETTIEKTETTMTTEMTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKS 1559
Query: 151 PA-----------TPASERPTRERKTVERYSVPS--PSKSAKSSGGKGLVIEKGRGEQLK 197
P PAS PT++ K+ E+ + P+ KS K EK E+LK
Sbjct: 1560 PVKKEKSPEKVEEKPAS--PTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELK 1617
Query: 198 DIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKE 257
+ S K DD + K+ K + S E+ + KE
Sbjct: 1618 S----PKEKSPEKADD------------KPKSPTKKEKSPEKSA-----TEDVKSPTKKE 1656
Query: 258 RIDKYVKEKLVDFCDVLNIPVSKGN--IKKEELSVKLLEFLENPQATTDVLLADNEKKVK 315
+ + V+EK P K + KK + VK E T + A KK K
Sbjct: 1657 KSPEKVEEKPTS-------PTKKESSPTKKTDDEVKSPTKKEKSPQTVEEKPASPTKKEK 1709
Query: 316 KRTRKVTPS-KSPGEASTETPAKKQKKTS--ESGKKRKGSSDVEEDEKAELSDAKDESQE 372
+ V KSP E S E +K K + E ++ + +V+ K E S K ++
Sbjct: 1710 SPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPEKSAEEK 1769
Query: 373 NVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNV 432
+ KES K ++E KS +K+ S + V+E K TK +KTP KS+
Sbjct: 1770 PKSPTKKES--SPVKMADDEVKSPTKKEKSPEKVEE----KPASPTKK-EKTPEKSAAEE 1822
Query: 433 DKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKAL 492
K+P K +++ + + SK K P + K ++ P S KK+ KS +A
Sbjct: 1823 LKSPTKK--EKSPSSPTKKTGDESKEKSPEKPEEKPKSPTPKKSPPGSPKKKKSKSPEAE 1880
Query: 493 VKDQGKSKSGKKAKAVPSREAMHAVVV 519
K K + V + H VV
Sbjct: 1881 KPPAPKLTRDLKLQTVNKTDLAHFEVV 1907
Score = 91.3 bits (225), Expect = 6e-18
Identities = 128/546 (23%), Positives = 218/546 (39%), Gaps = 87/546 (15%)
Query: 27 ETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDE--- 83
E K +++ + +E P+ + E + E +++ K K ++KE+ ++T+E
Sbjct: 1335 EVVSKTDSQTDVREGTPKRRVSFAEEELPKEVIDSDRKKKKSPSPDKKEKSPEKTEEKPA 1394
Query: 84 -----VKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKK 138
+EVK +EK + E EE + ++E++ + +K K+ P
Sbjct: 1395 SPTKKTGEEVKSPKEKSPASPT--KKEKSPAAEEVKSPTKKEKSPSSPTKKEKSPSSP-- 1450
Query: 139 GGKKETASEKKDPATPASERPTRERKTVER-YSVPSPSKSAKSSGGKGLV-------IEK 190
K+T E K+ + P S PT++ K+ E+ V SP K KS +V IEK
Sbjct: 1451 --TKKTGDEVKEKSPPKS--PTKKEKSPEKPEDVKSPVKKEKSPDATNIVEVSSETTIEK 1506
Query: 191 GR----GEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE 246
E + + K K + + ++ K+ K + S
Sbjct: 1507 TETTMTTEMTHESEESRTSVKKEKTPEKV--------DEKPKSPTKKDKSPEKS-----I 1553
Query: 247 NEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGN-IKKEELSVK------------LL 293
EE + KE+ + V+EK P + KK E VK ++
Sbjct: 1554 TEEIKSPVKKEKSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVV 1613
Query: 294 EFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSE------SGK 347
E L++P+ + D K K+ + +P KS E ++P KK+K + S
Sbjct: 1614 EELKSPKEKSPEKADDKPKSPTKKEK--SPEKSATE-DVKSPTKKEKSPEKVEEKPTSPT 1670
Query: 348 KRKGSSDVEEDEKAELSDAKDES----QENVAAPHKESDD------DESKSEEEEDKSKA 397
K++ S + D++ + K++S +E A+P K+ +E KS +E+ KA
Sbjct: 1671 KKESSPTKKTDDEVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKA 1730
Query: 398 QKKTSKKIVKEGSGSK-AGERTKS---AKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASA 453
++K KE S K A E KS +K+P KS++ K+P K D +
Sbjct: 1731 EEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPEKSAEEKPKSPTKKESSPVKMADDEVKS 1790
Query: 454 SLSKSKQPASKKRK----TENEKPDTKGKASSKKQTDKSSKA------LVKDQGKSKSGK 503
K K P + K T+ EK K A K K K+ D+ K KS +
Sbjct: 1791 PTKKEKSPEKVEEKPASPTKKEKTPEKSAAEELKSPTKKEKSPSSPTKKTGDESKEKSPE 1850
Query: 504 KAKAVP 509
K + P
Sbjct: 1851 KPEEKP 1856
Score = 71.6 bits (174), Expect = 5e-12
Identities = 63/266 (23%), Positives = 106/266 (39%), Gaps = 40/266 (15%)
Query: 281 GNIKKEELSVKLLEFLENPQATTDVL------------------LADNEKKVKKRTRKVT 322
G + + +SV +E + + TDV + D+++K KK
Sbjct: 1322 GGVTEGSISVSKIEVVSKTDSQTDVREGTPKRRVSFAEEELPKEVIDSDRKKKKSPSPDK 1381
Query: 323 PSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESD 382
KSP E + E PA KKT E K K S +K K + E V +P K+
Sbjct: 1382 KEKSP-EKTEEKPASPTKKTGEEVKSPKEKSPASPTKKE-----KSPAAEEVKSPTKKEK 1435
Query: 383 DDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKK-----TPVKSSKNVDKT-- 435
S +++E+ S KKT ++ ++ ++ KS +K +PVK K+ D T
Sbjct: 1436 SPSSPTKKEKSPSSPTKKTGDEVKEKSPPKSPTKKEKSPEKPEDVKSPVKKEKSPDATNI 1495
Query: 436 ---------PKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTD 486
K T T H+S + S K+ +K + + P K K+ K T+
Sbjct: 1496 VEVSSETTIEKTETTMTTEMTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITE 1555
Query: 487 KSSKALVKDQGKSKSGKKAKAVPSRE 512
+ + K++ K +K + +E
Sbjct: 1556 EIKSPVKKEKSPEKVEEKPASPTKKE 1581
Score = 58.2 bits (139), Expect = 6e-08
Identities = 111/519 (21%), Positives = 202/519 (38%), Gaps = 66/519 (12%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEA----EAEEKEAAPQEDEDASAEAVKSEAENAEEKDK 66
K P + E A+P +E + A ++E + +P + E + ++V E ++ +EK
Sbjct: 1565 KSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEKSP 1624
Query: 67 GGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEE---EQEEEEEAE 123
EK + +K K E E+ E+ + + E E EE+ ++E
Sbjct: 1625 ------EKAD-DKPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPT 1677
Query: 124 AEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVP---SPSKS--- 177
+ D++VK+ KK +T EK PA+P + + E+ VE P SP K+
Sbjct: 1678 KKTDDEVKSP--TKKEKSPQTVEEK--PASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEK 1733
Query: 178 AKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIG 237
KS K EK E++K P K ++ ++ + K+ K +
Sbjct: 1734 PKSPTKKEKSPEKSAAEEVKS-PTKKEKSPEKSAEE------------KPKSPTKKES-- 1778
Query: 238 QFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLE 297
S ++E K K KE+ + V+EK P + + + K
Sbjct: 1779 --SPVKMADDEVKSPTK-KEKSPEKVEEKPASPTKKEKTPEKSAAEELKSPTKKEKSPSS 1835
Query: 298 NPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE 357
+ T D + +K +++ + TP KSP +P KK+ K+ E+ ++ + +
Sbjct: 1836 PTKKTGDESKEKSPEKPEEKPKSPTPKKSP----PGSPKKKKSKSPEA--EKPPAPKLTR 1889
Query: 358 DEKAELSDAKDESQENVAAPHKES-----DDDESKSEEEEDKSKAQK---KTSKKIVKEG 409
D K + + D + V H D E + + SK + + S G
Sbjct: 1890 DLKLQTVNKTDLAHFEVVVEHATECKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFG 1949
Query: 410 SGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQ--------TAAEHDSASASLSKSKQP 461
SG+ + + +A K+ V +TPK++ + + D+ + P
Sbjct: 1950 SGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVIALHSP 2009
Query: 462 ASKKRKTENEKPDTKGKASSKKQTDKSSKAL--VKDQGK 498
K + N D K + K + +KSS + +D GK
Sbjct: 2010 LYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGK 2048
Score = 58.2 bits (139), Expect = 6e-08
Identities = 55/260 (21%), Positives = 107/260 (41%), Gaps = 11/260 (4%)
Query: 275 NIPVSKGNIKKEELSVKLLEFLE--NPQATTDVLLADNEKKVKKRTRKVTPSKSP-GEAS 331
++ V K ++ E+ ++ + ++ +P+ATT + + + K T T S G +
Sbjct: 1243 SVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTSTKTTTMSTTEVTSTVGGVT 1302
Query: 332 TETPAKKQKKTSE-----SGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDES 386
ET + + + SG +GS V + E +D++ + +E + S +E
Sbjct: 1303 VETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTPK-RRVSFAEEE 1361
Query: 387 KSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKS-AKKTPVKSSKNVDKTPKKSTPKQTA 445
+E D + +KK+ KE S K E+ S KKT + +K+P T K+ +
Sbjct: 1362 LPKEVIDSDRKKKKSPSPDKKEKSPEKTEEKPASPTKKTGEEVKSPKEKSPASPTKKEKS 1421
Query: 446 AEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKA 505
+ + K K P+S +K ++ TK K+ K++ K
Sbjct: 1422 PAAEEVKSPTKKEKSPSSPTKKEKSPSSPTKKTGDEVKEKSPPKSPTKKEKSPEKPEDVK 1481
Query: 506 KAVPSREAMHAV-VVDILKE 524
V ++ A +V++ E
Sbjct: 1482 SPVKKEKSPDATNIVEVSSE 1501
>CYL2_BOVIN (Q28092) Cylicin II (Multiple-band polypeptide II)
Length = 488
Score = 94.7 bits (234), Expect = 6e-19
Identities = 126/473 (26%), Positives = 190/473 (39%), Gaps = 91/473 (19%)
Query: 38 EKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEE 97
+KE P +++ A S ++DK E + V KE + K EE+ DE+
Sbjct: 100 QKETPPSQEDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAK-EEKPDEK 158
Query: 98 DEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASE 157
+ E + +G+E + E+E+A AE K K ++G KKG K+ P+ SE
Sbjct: 159 KDLKKERKDSKKGKESATESEDEKAGAEKGAK-KDRKGSKKG--------KETPSDSGSE 209
Query: 158 RPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHA 217
+ ++ + KS K S GK E GE+ K DD
Sbjct: 210 KGDAKKDS---------KKSKKDSKGKESATE-SEGEK-----------GDAKKDD---- 244
Query: 218 LHSILFGKRTKAYNLKRNIGQFSGFVWTENE-EKQRAKVKERIDKYVKEKLVDFCDVLNI 276
K+ K + K G+ S TE+E EK AK ++ K +K +
Sbjct: 245 -------KKGKKGSKK---GKESA---TESEGEKGDAKKDDKKGKKGSKKGKE--SATES 289
Query: 277 PVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPA 336
KG+ KK+ +KK KK ++K S + E
Sbjct: 290 EGEKGDAKKD------------------------DKKGKKGSKKGKESATESEGEKGDAK 325
Query: 337 KKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSK 396
K KK + KK K S+ E EK DAK + ++ K + D SK+E ++ +K
Sbjct: 326 KDDKKGKKGSKKGKESATESEGEK---GDAKKDDKKGKKGSKKGKESD-SKAEGDKGDAK 381
Query: 397 AQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLS 456
K KK GSK G+ + + + K SK DK KK K A E S
Sbjct: 382 KDDKKDKK------GSKKGKESATESEGEKKDSKK-DKAGKKDPTK--AGEKGDESKDKK 432
Query: 457 KSKQPASKKRKTENEKP---DTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
+K+ SKK K + +KP +++ K S+KK K +K K K + K AK
Sbjct: 433 DAKKKDSKKEKKDEKKPGEAESEPKDSAKKDAKKDAKKDAKKDAKKDAKKDAK 485
Score = 81.3 bits (199), Expect = 7e-15
Identities = 111/473 (23%), Positives = 180/473 (37%), Gaps = 100/473 (21%)
Query: 63 EKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
+K+ Q + K+ + + +VK K +ED+D + E E +E+ ++ +
Sbjct: 100 QKETPPSQEDAKQAAKPSSPKVK--------KSKEDKDKSDSEAESIVSKEKPRKLSKAK 151
Query: 123 EAEADEKVKAKRGPKKGGK-KETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSS 181
E + DEK K+ K K KE+A+E +D A + ++RK ++ K S
Sbjct: 152 EEKPDEKKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKGSKK------GKETPSD 205
Query: 182 GGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSG 241
G +G+ KD SK+ D+ GK +
Sbjct: 206 SGSE------KGDAKKD--------SKKSKKDSK--------GKESA------------- 230
Query: 242 FVWTENE-EKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQ 300
TE+E EK AK ++ K +K + KG+ KK++
Sbjct: 231 ---TESEGEKGDAKKDDKKGKKGSKKGKE--SATESEGEKGDAKKDD------------- 272
Query: 301 ATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEK 360
KK KK ++K S + E K KK + KK K S+ E EK
Sbjct: 273 -----------KKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEK 321
Query: 361 AELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGS-GSKAGERTK 419
DAK + K+ K +E +S+ +K +KK K+G GSK G+ +
Sbjct: 322 G---DAKKDD--------KKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESD 370
Query: 420 SAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTE--------NE 471
S + +K DK KK + K + +S K A KK T+ +
Sbjct: 371 SKAEGDKGDAKKDDKKDKKGSKKGKESATESEGEKKDSKKDKAGKKDPTKAGEKGDESKD 430
Query: 472 KPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAVVVDILKE 524
K D K K S K++ D+ + + K + K AK ++A D K+
Sbjct: 431 KKDAKKKDSKKEKKDEKKPGEAESEPKDSAKKDAKKDAKKDAKKDAKKDAKKD 483
Score = 80.1 bits (196), Expect = 1e-14
Identities = 114/458 (24%), Positives = 175/458 (37%), Gaps = 90/458 (19%)
Query: 43 PQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEV----KGEEEKDEED 98
PQ++ S E K A+ + K K + ++K + E E+ K++ K +EEK +E
Sbjct: 99 PQKETPPSQEDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEK 158
Query: 99 ED-GGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKG-------------GKKET 144
+D E + +G+E + E+E+A AE K K ++G KKG KK++
Sbjct: 159 KDLKKERKDSKKGKESATESEDEKAGAEKGAK-KDRKGSKKGKETPSDSGSEKGDAKKDS 217
Query: 145 ASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAF 204
KKD S + K + K +K E +G+ KD
Sbjct: 218 KKSKKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKD-DKKGK 276
Query: 205 KLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENE-EKQRAKVKERIDKYV 263
K SK+ GK + TE+E EK AK ++ K
Sbjct: 277 KGSKK--------------GKESA----------------TESEGEKGDAKKDDKKGKKG 306
Query: 264 KEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTP 323
+K + KG+ KK+ +KK KK ++K
Sbjct: 307 SKKGKE--SATESEGEKGDAKKD------------------------DKKGKKGSKKGKE 340
Query: 324 SKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDD 383
S + E K KK + KK K S E +K + KD+ ++ + K+ +
Sbjct: 341 SATESEGEKGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAK--KDDKKDKKGS--KKGKE 396
Query: 384 DESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTP--KKSTP 441
++SE E+ SK K K K G + K AKK K K +K P +S P
Sbjct: 397 SATESEGEKKDSKKDKAGKKDPTKAGEKGDESKDKKDAKKKDSKKEKKDEKKPGEAESEP 456
Query: 442 KQTAAEHDSASASLSK-SKQPASKKRKTENEKPDTKGK 478
K DSA K +K+ A K K + +K KGK
Sbjct: 457 K------DSAKKDAKKDAKKDAKKDAKKDAKKDAKKGK 488
Score = 78.2 bits (191), Expect = 6e-14
Identities = 116/439 (26%), Positives = 166/439 (37%), Gaps = 74/439 (16%)
Query: 23 PNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETD 82
P +QE + + K +ED+D S SEAE+ K+K + KEE E
Sbjct: 104 PPSQEDAKQAAKPSSPKVKKSKEDKDKS----DSEAESIVSKEKPRKLSKAKEEKPDEKK 159
Query: 83 EVK----DEVKGEEEKDE-EDEDGG-------EGEGEGEGEEEEEQEEEEEAEAEADEKV 130
++K D KG+E E EDE G + +G +G+E E+ +A+ D K
Sbjct: 160 DLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDSGSEKGDAKKDSKK 219
Query: 131 KAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSK-SAKSSGGKGLVIE 189
K K E+ EK D + +K E + K AK KG +
Sbjct: 220 SKKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKG---K 276
Query: 190 KGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENE- 248
KG + + + K DD K+ K + K G+ S TE+E
Sbjct: 277 KGSKKGKESATESEGEKGDAKKDD-----------KKGKKGSKK---GKESA---TESEG 319
Query: 249 EKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLA 308
EK AK ++ K +K + KG+ KK+
Sbjct: 320 EKGDAKKDDKKGKKGSKKGKE--SATESEGEKGDAKKD---------------------- 355
Query: 309 DNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKD 368
+KK KK ++K S S E K KK + KK K S+ E EK KD
Sbjct: 356 --DKKGKKGSKKGKESDSKAEGDKGDAKKDDKKDKKGSKKGKESATESEGEK------KD 407
Query: 369 ESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGS--GSKAGERTKSAKKTPV 426
++ A K+ K +E +DK A+KK SKK K+ G E SAKK
Sbjct: 408 SKKDK--AGKKDPTKAGEKGDESKDKKDAKKKDSKKEKKDEKKPGEAESEPKDSAKKDAK 465
Query: 427 KSSKNVDKTPKKSTPKQTA 445
K +K K K K+ A
Sbjct: 466 KDAKKDAKKDAKKDAKKDA 484
Score = 73.6 bits (179), Expect = 1e-12
Identities = 106/412 (25%), Positives = 182/412 (43%), Gaps = 59/412 (14%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEK-- 64
ED +K +AE + ++ E + +EK+ +E +D S + +S E+ +EK
Sbjct: 126 EDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLKKERKD-SKKGKESATESEDEKAG 184
Query: 65 -DKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE 123
+KG + + + KET KG+ +KD + + + + +G+E + E E+ +
Sbjct: 185 AEKGAKKDRKGSKKGKETPSDSGSEKGDAKKDSK-----KSKKDSKGKESATESEGEKGD 239
Query: 124 AEADEKVKAKRGPKKGGKKETASE-KKDPATPASERPTRERKTVERYSVPSPSK--SAKS 180
A+ D+K K K+G KKG + T SE +K A ++ + K + + S + AK
Sbjct: 240 AKKDDK-KGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKK 298
Query: 181 SGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFS 240
KG +KG + + + K DD K+ K + K G+ S
Sbjct: 299 DDKKG---KKGSKKGKESATESEGEKGDAKKDD-----------KKGKKGSKK---GKES 341
Query: 241 GFVWTENE-EKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENP 299
TE+E EK AK ++ K +K + KG+ KK++ K
Sbjct: 342 A---TESEGEKGDAKKDDKKGKKGSKKGKE--SDSKAEGDKGDAKKDDKKDKKGSKKGKE 396
Query: 300 QATTDVLLADNEKKVKKRTR--KVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE 357
AT ++ EKK K+ + K P+K+ GE E+ KK K +S K++K
Sbjct: 397 SATE----SEGEKKDSKKDKAGKKDPTKA-GEKGDESKDKKDAKKKDSKKEKK------- 444
Query: 358 DEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEG 409
DEK + +A+ E K+S ++K + ++D K KK +KK K+G
Sbjct: 445 DEK-KPGEAESEP--------KDSAKKDAKKDAKKDAKKDAKKDAKKDAKKG 487
Score = 71.2 bits (173), Expect = 7e-12
Identities = 80/294 (27%), Positives = 124/294 (41%), Gaps = 27/294 (9%)
Query: 310 NEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE---DEKAELSDA 366
+EKK K+ RK SK E++TE+ +K + K RKGS +E D +E DA
Sbjct: 156 DEKKDLKKERK--DSKKGKESATESEDEKAGAEKGAKKDRKGSKKGKETPSDSGSEKGDA 213
Query: 367 KDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPV 426
K +S+++ K+S ES +E E +K A+K K G ++ ++ K
Sbjct: 214 KKDSKKS----KKDSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAK 269
Query: 427 KSSKNVDKTPKKSTPKQTAAEHDSASASLSKSK-QPASKKRK---TENE-------KPDT 475
K K K KK T +E + A K + SKK K TE+E K D
Sbjct: 270 KDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDK 329
Query: 476 KGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAVVVDILKEVDFNTATLSDI 535
KGK SKK + ++++ +G+ KK + + D E D A D
Sbjct: 330 KGKKGSKKGKESATES----EGEKGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKDDK 385
Query: 536 LRQLGTHFGVD-LMHRKAEVKDIITDVINNMSDEE--DEGEEADGDGDADKDDN 586
+ G+ G + + E KD D + ++G+E+ DA K D+
Sbjct: 386 KDKKGSKKGKESATESEGEKKDSKKDKAGKKDPTKAGEKGDESKDKKDAKKKDS 439
Score = 69.3 bits (168), Expect = 3e-11
Identities = 81/322 (25%), Positives = 132/322 (40%), Gaps = 41/322 (12%)
Query: 292 LLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKG 351
L+ E P V LA + +K T PS+ + + + + K KK+ E K
Sbjct: 81 LMRISERPS----VYLAARSRHPQKET---PPSQEDAKQAAKPSSPKVKKSKEDKDKSDS 133
Query: 352 SSD--VEEDEKAELSDAKDESQENVAAPHKESDDD----ESKSEEEEDKSKAQK--KTSK 403
++ V +++ +LS AK+E + KE D ES +E E++K+ A+K K +
Sbjct: 134 EAESIVSKEKPRKLSKAKEEKPDEKKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDR 193
Query: 404 KIVKEG------SGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSK 457
K K+G SGS+ G+ K +KK+ K SK + + K A + D SK
Sbjct: 194 KGSKKGKETPSDSGSEKGDAKKDSKKSK-KDSKGKESATESEGEKGDAKKDDKKGKKGSK 252
Query: 458 SKQPA---SKKRKTENEKPDTKGKASSKKQTDKSSKA------LVKDQGKSKSGKKAKAV 508
+ + S+ K + +K D KGK SKK + ++++ KD K K G K
Sbjct: 253 KGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSKKGKE 312
Query: 509 PSREAMHAVVVDILKEVDFNTATLSDILRQLGTHFGVDLMHRKAEVKDIITDVINNMSDE 568
+ E+ E + A D + G+ G + K
Sbjct: 313 SATES----------EGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKG 362
Query: 569 EDEGEEADGDGDADKDDNGDDD 590
+G+E+D + DK D DD
Sbjct: 363 SKKGKESDSKAEGDKGDAKKDD 384
Score = 67.0 bits (162), Expect = 1e-10
Identities = 66/238 (27%), Positives = 104/238 (42%), Gaps = 19/238 (7%)
Query: 284 KKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPG---EASTETPAKKQK 340
K+ LL+ +P+ + L D ++ + + S+ P A + P K+
Sbjct: 45 KRRRSKPSLLQENTSPKYDAEKLRGDRKQPLWMHRSLMRISERPSVYLAARSRHPQKETP 104
Query: 341 KTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAA---PHKESDDDESKSEEEEDKSKA 397
+ E K+ S + + E D D E++ + P K S E K +E++D K
Sbjct: 105 PSQEDAKQAAKPSSPKVKKSKEDKDKSDSEAESIVSKEKPRKLSKAKEEKPDEKKDLKKE 164
Query: 398 QK--KTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASL 455
+K K K+ E KAG K AKK K SK +TP S ++ A+ DS +
Sbjct: 165 RKDSKKGKESATESEDEKAGAE-KGAKKDR-KGSKKGKETPSDSGSEKGDAKKDSKKSKK 222
Query: 456 -SKSKQPA--SKKRKTENEKPDTKGKASSKKQTDKSSKA------LVKDQGKSKSGKK 504
SK K+ A S+ K + +K D KGK SKK + ++++ KD K K G K
Sbjct: 223 DSKGKESATESEGEKGDAKKDDKKGKKGSKKGKESATESEGEKGDAKKDDKKGKKGSK 280
Score = 55.5 bits (132), Expect = 4e-07
Identities = 39/140 (27%), Positives = 69/140 (48%), Gaps = 22/140 (15%)
Query: 31 KGEAEAEEKE----AAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKE---TDE 83
KG+A+ ++K+ + ++ D+ AE K +A+ ++KDK G + ++ E E D
Sbjct: 349 KGDAKKDDKKGKKGSKKGKESDSKAEGDKGDAKKDDKKDKKGSKKGKESATESEGEKKDS 408
Query: 84 VKDEV----------KGEEEKDEEDEDGGEGEGEGE-----GEEEEEQEEEEEAEAEADE 128
KD+ KG+E KD++D + + E + GE E E ++ + +A+ D
Sbjct: 409 KKDKAGKKDPTKAGEKGDESKDKKDAKKKDSKKEKKDEKKPGEAESEPKDSAKKDAKKDA 468
Query: 129 KVKAKRGPKKGGKKETASEK 148
K AK+ KK KK+ K
Sbjct: 469 KKDAKKDAKKDAKKDAKKGK 488
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/184 (21%), Positives = 68/184 (36%), Gaps = 22/184 (11%)
Query: 327 PGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDES 386
PG+ P+ Q+ TS K D ++ S + + +V + +
Sbjct: 43 PGKRRRSKPSLLQENTSPKYDAEKLRGDRKQPLWMHRSLMRISERPSVYLAARSRHPQKE 102
Query: 387 KSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAA 446
+ED +A K +S K+ K +K+ KS + K P++
Sbjct: 103 TPPSQEDAKQAAKPSSPKV-------------KKSKEDKDKSDSEAESIVSKEKPRKL-- 147
Query: 447 EHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
S +K ++P KK + K KGK S+ + D+ + A + K KK K
Sbjct: 148 -------SKAKEEKPDEKKDLKKERKDSKKGKESATESEDEKAGAEKGAKKDRKGSKKGK 200
Query: 507 AVPS 510
PS
Sbjct: 201 ETPS 204
>NFH_RAT (P16884) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H) (Fragment)
Length = 831
Score = 93.6 bits (231), Expect = 1e-18
Identities = 124/550 (22%), Positives = 208/550 (37%), Gaps = 65/550 (11%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDK 66
E K PV+ E A E K AEA+ S VKS AE
Sbjct: 274 EKETKSPVKEEAKSPAEAKSPAEAKSPAEAKSPAEVKSPAVAKSPAEVKSPAEVKSP--- 330
Query: 67 GGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEA 126
E K E ++ EVK E E + E + E + AEA++
Sbjct: 331 ----AEAKSPAEAKSPA---EVKSPATVKSPGEAKSPAEAKSPAEVKSPAEAKSPAEAKS 383
Query: 127 DEKVKAKRGPKKGGKKETASEKKDPATPAS----------------ERPTRERKTVE--- 167
VK+ K + ++ +E K PAT S + P + VE
Sbjct: 384 PASVKSPGEAKSPAEAKSPAEVKSPATVKSPVEAKSPAEVKSPVTVKSPAEAKSPVEVKS 443
Query: 168 RYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRT 227
SV SPS++ +G K + + + P A + KP +
Sbjct: 444 PASVKSPSEAKSPAGAKSPA--EAKSPVVAKSPAEAKSPAGAKPPAEAKSPAEAKSPAEA 501
Query: 228 KAYNLKRNIGQFSGFVWTENEEKQRAKVK------------ERIDKYVKEKLVDFCDVLN 275
K+ ++ + V ++ EK ++ VK E+ VKE++ +V +
Sbjct: 502 KSPAEAKSPAEAKSPVEVKSPEKAKSPVKEGAKSLAEAKSPEKAKSPVKEEIKPPAEVKS 561
Query: 276 IPVSKGNIKKEELSVKLLEFLE--NPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTE 333
+K ++KE S + + L+ +P+A A E K R KSP + +
Sbjct: 562 PEKAKSPMRKEAKSPEKAKTLDVKSPEAKPP---AKEEAKRPADIRSPEQVKSPAKEEAK 618
Query: 334 TPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPH---KESDDDESKSEE 390
+P K++ +T + K++ E+ KA+ K E ++ A P KES DE+ E
Sbjct: 619 SPEKEETRTEKVAPKKEEVKSPVEEVKAKEPPKKVEEEKTPATPKTEVKESKKDEAPKEA 678
Query: 391 EEDKSKAQKKTSKKIVKEGSGSKAGERTKSAK------KTPVKSSKNVDKTPKKSTPKQT 444
++ K++ ++ ++K K+ G E K K +TP K + PK+
Sbjct: 679 QKPKAEEKEPLTEK-PKDSPGEAKKEEAKEKKAAAPEEETPAKLGVKEEAKPKEKAEDAK 737
Query: 445 AAEHDSASASLSKSKQ--PASKKRKTENEKPDTKGKASSKK-----QTDKSSKALVKDQG 497
A E S K+ PA+ ++K E+ T+ K +K + + K L ++
Sbjct: 738 AKEPSKPSEKEKPKKEEVPAAPEKKDTKEEKTTESKKREEKPKMEAKAKEEDKGLPQEPS 797
Query: 498 KSKSGKKAKA 507
K K+ K K+
Sbjct: 798 KPKTEKAEKS 807
Score = 86.3 bits (212), Expect = 2e-16
Identities = 113/491 (23%), Positives = 197/491 (40%), Gaps = 36/491 (7%)
Query: 50 SAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGE 109
S E +K ++ +E +Q EE + E+ T+E E +GEEE EE E+GGE
Sbjct: 207 SEEKIKVVEKSEKETVIVEEQTEEIQVTEEVTEEEDKEAQGEEE--EEAEEGGEEAATTS 264
Query: 110 GEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPA---TPASERPTRERKTV 166
EE E+E ++ E+ K+ K + ++ +E K PA +PA + E K+
Sbjct: 265 PPAEEAASPEKETKSPVKEEAKSPAEAKSPAEAKSPAEAKSPAEVKSPAVAKSPAEVKSP 324
Query: 167 ERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKR 226
P+ +KS + V + P A ++ K + +
Sbjct: 325 AEVKSPAEAKSPAEAKSPAEV----KSPATVKSPGEAKSPAEAKSPAEVKSPAEAKSPAE 380
Query: 227 TKAYNLKRNIGQFSGFVWTEN--EEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIK 284
K+ ++ G+ ++ E K A VK ++ ++ V + +K ++
Sbjct: 381 AKSPASVKSPGEAKSPAEAKSPAEVKSPATVKSPVEAKSPAEVKSPVTVKSPAEAKSPVE 440
Query: 285 -KEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAK---KQK 340
K SVK ++P K + +KSP EA + AK + K
Sbjct: 441 VKSPASVKSPSEAKSPAGA----------KSPAEAKSPVVAKSPAEAKSPAGAKPPAEAK 490
Query: 341 KTSESGKKRKGSSDVEEDEKAEL-SDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQK 399
+E+ + S E AE S + +S E +P KE +KS E + K
Sbjct: 491 SPAEAKSPAEAKSPAEAKSPAEAKSPVEVKSPEKAKSPVKEG----AKSLAEAKSPEKAK 546
Query: 400 KTSKKIVKEGSGSKAGERTKSAKKTPVKS---SKNVD-KTPKKSTPKQTAAEHDSASASL 455
K+ +K + K+ E+ KS + KS +K +D K+P+ P + A+ + S
Sbjct: 547 SPVKEEIKPPAEVKSPEKAKSPMRKEAKSPEKAKTLDVKSPEAKPPAKEEAKRPADIRSP 606
Query: 456 SKSKQPASKKRKTENEKPDTKGKASSKKQTDKS--SKALVKDQGKSKSGKKAKAVPSREA 513
+ K PA ++ K+ ++ K + KK+ KS + K+ K +K A P E
Sbjct: 607 EQVKSPAKEEAKSPEKEETRTEKVAPKKEEVKSPVEEVKAKEPPKKVEEEKTPATPKTEV 666
Query: 514 MHAVVVDILKE 524
+ + KE
Sbjct: 667 KESKKDEAPKE 677
Score = 74.3 bits (181), Expect = 8e-13
Identities = 108/519 (20%), Positives = 190/519 (35%), Gaps = 42/519 (8%)
Query: 33 EAEAEE----KEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDE-VKDE 87
E + EE +E +ED++A E + E EE EE EKET VK+E
Sbjct: 225 EEQTEEIQVTEEVTEEEDKEAQGEEEEEAEEGGEEAATTSPPAEEAASPEKETKSPVKEE 284
Query: 88 VKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASE 147
K E E E + E + + AE ++ +VK+ K + ++ +E
Sbjct: 285 AKSPAEAKSPAEAKSPAEAKSPAEVKSPAVAKSPAEVKSPAEVKSPAEAKSPAEAKSPAE 344
Query: 148 KKDPAT---------PASERPTRERKTVERYSVPSPSKS---AKSSGGKGLVIEKGRGEQ 195
K PAT PA + E K+ P+ +KS KS G E +
Sbjct: 345 VKSPATVKSPGEAKSPAEAKSPAEVKSPAEAKSPAEAKSPASVKSPGEAKSPAEAKSPAE 404
Query: 196 LKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKV 255
+K V + + P + + + +K V + +E K A
Sbjct: 405 VKSPATVKSPVEAKSPAEVKSPVTVKSPAEAKSPVEVKSPAS-----VKSPSEAKSPAGA 459
Query: 256 KERIDKYVKEKLVDFCDVLNIPVSKGNIK-KEELSVKLLEFLENPQATTDVLLADNEKKV 314
K + + + +K + K K ++P A + +V
Sbjct: 460 KSPAEAKSPVVAKSPAEAKSPAGAKPPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPVEV 519
Query: 315 KKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENV 374
K + +P K ++ E + ++ K S ++ K ++V+ EKA+ K+
Sbjct: 520 KSPEKAKSPVKEGAKSLAEAKSPEKAK-SPVKEEIKPPAEVKSPEKAKSPMRKEAKSPEK 578
Query: 375 AAPHKESDDDESKSEEEEDKSKAQKKTSKKI---VKEGSGSKAGERTKSAKKTPVKSS-- 429
A + +EE K A ++ +++ KE + S E T++ K P K
Sbjct: 579 AKTLDVKSPEAKPPAKEEAKRPADIRSPEQVKSPAKEEAKSPEKEETRTEKVAPKKEEVK 638
Query: 430 ------------KNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKG 477
K V++ +TPK E A K A +K + D+ G
Sbjct: 639 SPVEEVKAKEPPKKVEEEKTPATPKTEVKESKKDEAPKEAQKPKAEEKEPLTEKPKDSPG 698
Query: 478 KASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHA 516
+A ++ +K + A +++ +K G K +A P +A A
Sbjct: 699 EAKKEEAKEKKA-AAPEEETPAKLGVKEEAKPKEKAEDA 736
Score = 73.2 bits (178), Expect = 2e-12
Identities = 119/530 (22%), Positives = 204/530 (38%), Gaps = 39/530 (7%)
Query: 14 VQAEGDDAAPNNQETEVKG-EAEAEEKEAAPQEDEDASAEAVKSE-AENAEEKDKGGDQV 71
V+ + ++ + TE + EA+ EE+E A + E+A+ + +E A + E++ K +
Sbjct: 224 VEEQTEEIQVTEEVTEEEDKEAQGEEEEEAEEGGEEAATTSPPAEEAASPEKETKSPVKE 283
Query: 72 EEKEEVE-------KETDEVKD--EVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
E K E K E K EVK E E + E + E + A
Sbjct: 284 EAKSPAEAKSPAEAKSPAEAKSPAEVKSPAVAKSPAEVKSPAEVKSPAEAKSPAEAKSPA 343
Query: 123 EAEADEKVKAKRGPKKGGKKETASEKKDPA---TPASERPTRERKTVERYSVPSPSKS-- 177
E ++ VK+ K + ++ +E K PA +PA + K+ P+ +KS
Sbjct: 344 EVKSPATVKSPGEAKSPAEAKSPAEVKSPAEAKSPAEAKSPASVKSPGEAKSPAEAKSPA 403
Query: 178 -AKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNI 236
KS +E ++K V + P + + + S+ K+ ++
Sbjct: 404 EVKSPATVKSPVEAKSPAEVKSPVTVKSPAEAKSPVE-VKSPASVKSPSEAKSPAGAKSP 462
Query: 237 GQFSGFVWTEN--EEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIK-KEELSVKLL 293
+ V ++ E K A K + + + + +K + K + VK
Sbjct: 463 AEAKSPVVAKSPAEAKSPAGAKPPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPVEVKSP 522
Query: 294 EFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEAST----ETPAKKQKKTSESGKKR 349
E ++P LA+ + K ++ K P E + ++P +K+ K+ E K
Sbjct: 523 EKAKSPVKEGAKSLAEAKSPEKAKSPVKEEIKPPAEVKSPEKAKSPMRKEAKSPEKAKTL 582
Query: 350 K-GSSDVEEDEKAELSDAKD-ESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVK 407
S + + K E D S E V +P KE K E +K +K+ K V+
Sbjct: 583 DVKSPEAKPPAKEEAKRPADIRSPEQVKSPAKEEAKSPEKEETRTEKVAPKKEEVKSPVE 642
Query: 408 EGSGSK-----AGERTKSAKKTPVKSSKNVDKTPK-----KSTPKQTAAEHDSASASLSK 457
E + E+T + KT VK SK D+ PK K+ K+ E S +K
Sbjct: 643 EVKAKEPPKKVEEEKTPATPKTEVKESKK-DEAPKEAQKPKAEEKEPLTEKPKDSPGEAK 701
Query: 458 SKQPASKKRKT-ENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
++ KK E E P G K +K+ A K+ K +K K
Sbjct: 702 KEEAKEKKAAAPEEETPAKLGVKEEAKPKEKAEDAKAKEPSKPSEKEKPK 751
Score = 61.2 bits (147), Expect = 7e-09
Identities = 58/265 (21%), Positives = 114/265 (42%), Gaps = 9/265 (3%)
Query: 246 ENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEF--LENPQATT 303
E+ E+QR+++++R + + + D + ++ K E++ +L E+ L N +
Sbjct: 107 ESLERQRSELEDRH----QVDMASYQDAIQQLDNELRNTKWEMAAQLREYQDLLNVKMAL 162
Query: 304 DVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAEL 363
D+ +A K ++ ++ P + P T K + VE+ EK +
Sbjct: 163 DLEIAAYRKLLEGEECRIGFGPIPFSLTEGLPKIPSMSTHIKVKSEEKIKVVEKSEKETV 222
Query: 364 SDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKK 423
+ + V E +D E++ EEEE+ + ++ + + + TKS K
Sbjct: 223 IVEEQTEEIQVTEEVTEEEDKEAQGEEEEEAEEGGEEAATTSPPAEEAASPEKETKSPVK 282
Query: 424 TPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKP-DTKGKASSK 482
KS + +P + + + S +++KS PA K E + P + K A +K
Sbjct: 283 EEAKSPAEAKSPAEAKSPAEAKSPAEVKSPAVAKS--PAEVKSPAEVKSPAEAKSPAEAK 340
Query: 483 KQTDKSSKALVKDQGKSKSGKKAKA 507
+ S A VK G++KS +AK+
Sbjct: 341 SPAEVKSPATVKSPGEAKSPAEAKS 365
Score = 60.8 bits (146), Expect = 9e-09
Identities = 56/214 (26%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 299 PQATTDVLLADNEK-KVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE 357
P +T + + EK KV +++ K T E TE ++ T E K+ +G + E
Sbjct: 197 PSMSTHIKVKSEEKIKVVEKSEKETVIV---EEQTEEIQVTEEVTEEEDKEAQGEEEEEA 253
Query: 358 DEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGE- 416
+E E + E A+P KE+ +EE KS A+ K+ + E
Sbjct: 254 EEGGEEAATTSPPAEEAASPEKET----KSPVKEEAKSPAEAKSPAEAKSPAEAKSPAEV 309
Query: 417 RTKSAKKTP--VKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKP- 473
++ + K+P VKS V + +P + + + S + KS P K E + P
Sbjct: 310 KSPAVAKSPAEVKSPAEVKSPAEAKSPAEAKSPAEVKSPATVKS--PGEAKSPAEAKSPA 367
Query: 474 DTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA 507
+ K A +K + S A VK G++KS +AK+
Sbjct: 368 EVKSPAEAKSPAEAKSPASVKSPGEAKSPAEAKS 401
Score = 55.5 bits (132), Expect = 4e-07
Identities = 55/208 (26%), Positives = 94/208 (44%), Gaps = 26/208 (12%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAE-----EKEAAPQEDEDA------- 49
A +++ KPP + + + A + E K +A+ EA P E+A
Sbjct: 545 AKSPVKEEIKPPAEVKSPEKAKSPMRKEAKSPEKAKTLDVKSPEAKPPAKEEAKRPADIR 604
Query: 50 SAEAVKS----EAENAEEKDKGGDQV-EEKEEVEKETDEVKDE---VKGEEEK-----DE 96
S E VKS EA++ E+++ ++V +KEEV+ +EVK + K EEEK
Sbjct: 605 SPEQVKSPAKEEAKSPEKEETRTEKVAPKKEEVKSPVEEVKAKEPPKKVEEEKTPATPKT 664
Query: 97 EDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPAS 156
E ++ + E E ++ + +E+E E D +AK+ K KK A E++ PA
Sbjct: 665 EVKESKKDEAPKEAQKPKAEEKEPLTEKPKDSPGEAKKEEAK-EKKAAAPEEETPAKLGV 723
Query: 157 ERPTRERKTVERYSVPSPSKSAKSSGGK 184
+ + ++ E PSK ++ K
Sbjct: 724 KEEAKPKEKAEDAKAKEPSKPSEKEKPK 751
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 27/192 (14%)
Query: 11 KPPVQAEGDDAAPNNQETEVKG-----------EAEAEEKEAAPQEDEDASAEAVKSEAE 59
+PP + E ++ P +TEVK + +AEEKE ++ +D+ EA K EA
Sbjct: 648 EPPKKVE-EEKTPATPKTEVKESKKDEAPKEAQKPKAEEKEPLTEKPKDSPGEAKKEEA- 705
Query: 60 NAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEE---- 115
K+K EE+ + VK+E K +E+ ++ E E ++EE
Sbjct: 706 ----KEKKAAAPEEETPAKLG---VKEEAKPKEKAEDAKAKEPSKPSEKEKPKKEEVPAA 758
Query: 116 QEEEEEAEAEADEKVKAKRGPK--KGGKKETASEKKDPATPASERPTRERKTVERYSVPS 173
E+++ E + E K + PK K+E ++P+ P +E+ + T ++ S PS
Sbjct: 759 PEKKDTKEEKTTESKKREEKPKMEAKAKEEDKGLPQEPSKPKTEKAEKSSSTDQKDSQPS 818
Query: 174 PSKSAKSSGGKG 185
K+ + KG
Sbjct: 819 -EKAPEDKAAKG 829
Score = 42.4 bits (98), Expect = 0.003
Identities = 36/139 (25%), Positives = 61/139 (42%), Gaps = 24/139 (17%)
Query: 23 PNNQETEVKGEAEAEEKEAAPQED-----------------EDASAEAVKSEAENAEEKD 65
P + E K E E+K AAP+E+ EDA A+ +E + K
Sbjct: 693 PKDSPGEAKKEEAKEKKAAAPEEETPAKLGVKEEAKPKEKAEDAKAKEPSKPSEKEKPKK 752
Query: 66 KGGDQVEEKEEV--EKETDEVKDEVKGEEEKDEEDEDGG--EGEGEGEGEEEEEQEEEEE 121
+ EK++ EK T+ K E K + E ++ED G + + + E+ E+ ++
Sbjct: 753 EEVPAAPEKKDTKEEKTTESKKREEKPKMEAKAKEEDKGLPQEPSKPKTEKAEKSSSTDQ 812
Query: 122 AEAEADEKV---KAKRGPK 137
+++ EK KA +G K
Sbjct: 813 KDSQPSEKAPEDKAAKGDK 831
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 92.8 bits (229), Expect = 2e-18
Identities = 118/517 (22%), Positives = 216/517 (40%), Gaps = 81/517 (15%)
Query: 32 GEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVK-- 89
G +E+E+ + EDED + + EN E K+K +++EK E E + K K
Sbjct: 4 GVSESEDSDGHVIEDEDLE---MARQIEN-ERKEKRAQKLKEKREREGKPPPKKRPAKKR 59
Query: 90 --GEEEKDEEDED--------GGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKG 139
E+D++DE+ + E E +E EEE+ ++++ +KV K+ K
Sbjct: 60 KASSSEEDDDDEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSK 119
Query: 140 GKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDI 199
K+ T+S + + + E+ ++++ + S S K ++K + + K +
Sbjct: 120 KKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERK---VKKSKKNKEKSV 176
Query: 200 PNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERI 259
A + S+ +D + K++K LK+ S E+E + +VK+
Sbjct: 177 KKRA-ETSEESDEDEKPS-------KKSKK-GLKKKAKSES-----ESESEDEKEVKKSK 222
Query: 260 DKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTR 319
K SK +KKE S E P+ +KK +KR R
Sbjct: 223 KK-----------------SKKVVKKESESED-----EAPE----------KKKTEKRKR 250
Query: 320 KVTPSKSPGEASTETPAKKQKKTSESGKKRK--GSSDVEEDEKAELSDAK--DESQENVA 375
T S+ E+ +++K++S KK+K + DE++E SD + + ++ A
Sbjct: 251 SKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDVEVLPQKKKRGA 310
Query: 376 APHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKT 435
+DE + E + S ++K SKK K+ S++G + T + SK +K
Sbjct: 311 VTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKSKKKEKP 370
Query: 436 PKKS-----TPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSS- 489
KK + E A + + ++ KK+K N +G+ ++ T SS
Sbjct: 371 EKKKKGIIMDSSKLQKETIDAERAEKERRKRLEKKQKEFNGIVLEEGEDLTEMLTGTSSQ 430
Query: 490 ---KALVKDQGKSKSGKKAKAVPSREAMHAVVVDILK 523
K++V D S +++K +H +V ILK
Sbjct: 431 RKLKSVVLDPDSSTVDEESK---KPVEVHNSLVRILK 464
Score = 84.3 bits (207), Expect = 8e-16
Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 18/212 (8%)
Query: 312 KKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGS--SDVEEDEKAELSDAKDE 369
KK + RK + S+ + E+P K KK+ + K S SD EED K S K +
Sbjct: 52 KKRPAKKRKASSSEEDDDDEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVD 111
Query: 370 SQENVAAPHKE---SDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPV 426
++ + K S +DE EE E KSK + K +KK + S++ E ++ +K
Sbjct: 112 QKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKK----QTSSESSEESEEERKVK- 166
Query: 427 KSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRK------TENEKPDTKGKAS 480
KS KN +K+ KK +T+ E D KSK+ KK K +E+EK K K
Sbjct: 167 KSKKNKEKSVKKRA--ETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKK 224
Query: 481 SKKQTDKSSKALVKDQGKSKSGKKAKAVPSRE 512
SKK K S++ + K K+ K+ ++ S E
Sbjct: 225 SKKVVKKESESEDEAPEKKKTEKRKRSKTSSE 256
Score = 84.3 bits (207), Expect = 8e-16
Identities = 75/220 (34%), Positives = 109/220 (49%), Gaps = 29/220 (13%)
Query: 309 DNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKD 368
+NE+K +KR +K+ K E + P KK+ KKRK SS E+D+ E S K
Sbjct: 28 ENERK-EKRAQKL---KEKREREGKPPPKKRP-----AKKRKASSSEEDDDDEEESPRKS 78
Query: 369 ESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKS 428
+ A ES+ DES EE+ KSK++KK +K KE S K RT S+ +
Sbjct: 79 SKKSRKRAK-SESESDESDEEEDRKKSKSKKKVDQK-KKEKSKKK---RTTSSSEDEDSD 133
Query: 429 SKNVDKTPKKS--TPKQTAAEHDSASAS------LSKSKQPASKKR------KTENEKPD 474
+ K+ KKS T KQT++E S K+K+ + KKR E+EKP
Sbjct: 134 EEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPS 193
Query: 475 TKGKASSKKQTDKSSKALVKDQGK-SKSGKKAKAVPSREA 513
K K KK+ S++ +D+ + KS KK+K V +E+
Sbjct: 194 KKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKES 233
Score = 74.3 bits (181), Expect = 8e-13
Identities = 110/498 (22%), Positives = 190/498 (38%), Gaps = 98/498 (19%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
E E KPP + P + E + +++E +P++ S + KSE+E+ E
Sbjct: 41 EKREREGKPPPKKR-----PAKKRKASSSEEDDDDEEESPRKSSKKSRKRAKSESESDES 95
Query: 64 -----------KDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEE 112
K K + +EK + ++ T +DE EE + + + + + + E
Sbjct: 96 DEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSES 155
Query: 113 EEEQEEEEEA-------------------EAEADEKV--KAKRGPKKGGKKETASEKKDP 151
EE EEE + E++ DEK K+K+G KK K E+ SE +D
Sbjct: 156 SEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESED- 214
Query: 152 ATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKP 211
K K S K + K E + P K+K
Sbjct: 215 -----------------------EKEVKKSKKKSKKVVKKESESEDEAP------EKKKT 245
Query: 212 DDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKE--RIDKYVKEKLVD 269
+ KR+K + + + + S E E + K K+ + K ++ +
Sbjct: 246 EKR----------KRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESE 295
Query: 270 FCDVLNIPVSKGNIKKEELSVKLLEFLENPQ-ATTDVLLADNEKKVKKRTRKVTPSKSPG 328
DV +P KK+ +V L+ E+ + ++ +D E+KV K+ K S G
Sbjct: 296 ESDVEVLPQ-----KKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESG 350
Query: 329 EASTE---TPAKKQKKTSESGKKRKG-SSDVEEDEKAELSDAKDESQENVAAPHKESDDD 384
S+E T +K KK + KK+KG D + +K + + E + K+ + +
Sbjct: 351 SDSSEGSITVNRKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKERRKRLEKKQKEFN 410
Query: 385 ESKSEEEEDKSKAQKKTS-----KKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKS 439
EE ED ++ TS K +V + S E +K PV+ ++ + K
Sbjct: 411 GIVLEEGEDLTEMLTGTSSQRKLKSVVLDPDSSTVDEESKK----PVEVHNSLVRILKPH 466
Query: 440 TPKQTAAEHDSASASLSK 457
+D A SL +
Sbjct: 467 QAHGIQFMYDCACESLDR 484
Score = 73.6 bits (179), Expect = 1e-12
Identities = 80/350 (22%), Positives = 145/350 (40%), Gaps = 45/350 (12%)
Query: 246 ENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDV 305
E +EK+ K+KE+ ++ K P K KK + S D
Sbjct: 30 ERKEKRAQKLKEKREREGKP-----------PPKKRPAKKRKAS---------SSEEDDD 69
Query: 306 LLADNEKKVKKRTRKVTPSKSPGEASTETPAKK---------QKKTSESGKKRKGSSDVE 356
++ +K K++RK S+S + S E +K QKK +S KKR SS +
Sbjct: 70 DEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSED 129
Query: 357 EDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGE 416
ED DE +E + + ++ SE E+ + +K K KE S K E
Sbjct: 130 EDS--------DEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAE 181
Query: 417 RTKSA--KKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPD 474
++ + + P K SK K KS + + + S KSK+ K+ ++E+E P+
Sbjct: 182 TSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPE 241
Query: 475 TKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAVVVDILKEVDFNTATLSD 534
K K +K++ SS+ + + + ++ ++ P + + V L + + + +
Sbjct: 242 KK-KTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDVE 300
Query: 535 ILRQLGTHFGVDLMHRKAEVKD-----IITDVINNMSDEEDEGEEADGDG 579
+L Q V L+ + KD +DV +S ++ + +E+ G
Sbjct: 301 VLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESG 350
Score = 34.7 bits (78), Expect = 0.72
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 76 EVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRG 135
E E + V E EE +D DG E E EG + E + + +D++ +K+
Sbjct: 802 EQRMERERVMREDAEEEADFIDDGDGSESESEGSFKSGSESDSGKSVVLSSDDEGSSKK- 860
Query: 136 PKKGGK---KETASEKK 149
K G K K+TA +KK
Sbjct: 861 KKNGNKPEIKKTAPQKK 877
Score = 33.5 bits (75), Expect = 1.6
Identities = 21/91 (23%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 33 EAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEE 92
E+E+E + E + + + S+ E + +K K G+ K E++K + K + +
Sbjct: 829 ESESEGSFKSGSESDSGKSVVLSSDDEGSSKKKKNGN----KPEIKKTAPQKKRKFLNSD 884
Query: 93 EKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE 123
++DEED + +G + ++ EEA+
Sbjct: 885 DEDEEDGEDTAMAILQDGIRQSKRLAGEEAD 915
>NFM_RAT (P12839) Neurofilament triplet M protein (160 kDa
neurofilament protein) (Neurofilament medium
polypeptide) (NF-M)
Length = 845
Score = 92.4 bits (228), Expect = 3e-18
Identities = 105/410 (25%), Positives = 173/410 (41%), Gaps = 72/410 (17%)
Query: 29 EVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGD----QVEEKEEVEKETDEV 84
E K E E E E A + A + K E E AEEK++ + V+ E E+E E
Sbjct: 458 ETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEKEEEPEVEKSPVKSPEAKEEEEGEK 517
Query: 85 KDEVKGEEEKDEEDE-------DGGEGEGEGEGEEEE-EQEEEEEAEAEAD-EKVKAKRG 135
++E +G+EE++EEDE + G E EG E++E EQEEE E EAE + E+ +AK
Sbjct: 518 EEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQEEEGETEAEGEGEEAEAKEE 577
Query: 136 PKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQ 195
K GK E + K++ E+P + + V + V ++ GK E+ + E+
Sbjct: 578 KKTEGKVEEMAIKEEIKV---EKPEKAKSPVPKSPVEEVKPKPEAKAGKDEQKEEEKVEE 634
Query: 196 LKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKV 255
K++ + K K V + E+ +
Sbjct: 635 KKEVAKESPKEEK----------------------------------VEKKEEKPKDVPD 660
Query: 256 KERIDKYVKEKLVDFCDVLNIPVS-KGNIKKEELSVKLLEFLENPQATTDVLLADNEKKV 314
K++ + VKEK V+ +++ I S K +++K+ E PQ ++KV
Sbjct: 661 KKKAESPVKEKAVE--EMITITKSVKVSLEKDTKE-------EKPQ---------QQEKV 702
Query: 315 KKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENV 374
K++ + S+ E ++P + +K+ + +G + EE E E ++E + V
Sbjct: 703 KEKAEEEGGSEE--EVGDKSPQESKKEDIAINGEVEGKEE-EEQETQEKGSGQEEEKGVV 759
Query: 375 AAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKT 424
S +E K E+ D K +KI EG TKS T
Sbjct: 760 TNGLDVSPAEEKKGEDRSDDKVVVTKKVEKITSEGGDGATKYITKSVTVT 809
Score = 86.7 bits (213), Expect = 2e-16
Identities = 122/500 (24%), Positives = 204/500 (40%), Gaps = 84/500 (16%)
Query: 3 TETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA- 61
T L H +P V Q+T+V+ + + + E+ E KSE E+A
Sbjct: 418 TGPLYTHRQPSVTISS-----KIQKTKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEDAL 472
Query: 62 -----EEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQ 116
E ++ EE EE E+E + K VK E K+EE+ + E E EG+ EEEEE
Sbjct: 473 TVIAEELAASAKEEKEEAEEKEEEPEVEKSPVKSPEAKEEEEGEKEEEE-EGQEEEEEE- 530
Query: 117 EEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSK 176
DE VK+ + + G +KE +SEK + E+ E + +K
Sbjct: 531 ----------DEGVKSDQAEEGGSEKEGSSEKDE-----GEQEEEGETEAEGEGEEAEAK 575
Query: 177 SAKSSGGKGLVIEKGRGEQLK-DIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRN 235
K + GK V E E++K + P A + P + + GK
Sbjct: 576 EEKKTEGK--VEEMAIKEEIKVEKPEKAKSPVPKSPVEEVKPKPEAKAGK---------- 623
Query: 236 IGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEF 295
+E+K+ KV+E+ + V+K + K+E++ K
Sbjct: 624 -----------DEQKEEEKVEEKKE-----------------VAKESPKEEKVEKK---- 651
Query: 296 LENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDV 355
E P+ D A++ K K +T +KS + S E K++K + K K +
Sbjct: 652 EEKPKDVPDKKKAESPVKEKAVEEMITITKSV-KVSLEKDTKEEKPQQQEKVKEKAEEEG 710
Query: 356 EEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAG 415
+E+ ++ +E++A + E + E + +E ++K Q++ K +V G
Sbjct: 711 GSEEEVGDKSPQESKKEDIAI-NGEVEGKEEEEQETQEKGSGQEE-EKGVVTNGLDVSPA 768
Query: 416 ERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDT 475
E KK +S V T K K T+ D A+ ++KS K E+E+
Sbjct: 769 EE----KKGEDRSDDKVVVT--KKVEKITSEGGDGATKYITKSVTVTQKVE--EHEETFE 820
Query: 476 KGKASSKKQTDKSSKALVKD 495
+ S+KK +S A+VK+
Sbjct: 821 EKLVSTKKVEKVTSHAIVKE 840
Score = 73.2 bits (178), Expect = 2e-12
Identities = 129/636 (20%), Positives = 248/636 (38%), Gaps = 85/636 (13%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA 61
AT + +H K VQ + D + E ++ E E+EA ++D +A+ AV+ + E +
Sbjct: 157 ATLEMVNHEKAQVQLDSD-----HLEEDIHRLKERFEEEARLRDDTEAAIRAVRKDIEES 211
Query: 62 EEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQ----- 116
K E++K+ ++DEV EE+ + + E +
Sbjct: 212 SMV---------KVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKT 262
Query: 117 -------EEEEEAEAEADEKV-KAKRGPKKGGKK--ETASEKKDPATPASERPTRERKTV 166
E + E +D+ + +A+ K K E A + K+ A E R+ +
Sbjct: 263 DISTALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQL 322
Query: 167 ERYSVPSPS-KSAKSSGGKGLV-IEKGRGEQLKDIPNVAFKLS----------------- 207
+ S+ S + K S + L IE+ L + +L
Sbjct: 323 QSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREY 382
Query: 208 ------KRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDK 261
K D + A +L G+ T+ G +G ++T + K + K
Sbjct: 383 QDLLNVKMALDIEIAAYRKLLEGEETRFSTFS---GSITGPLYTHRQPSVTISSKIQKTK 439
Query: 262 YVKEKLV---DFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRT 318
KL F + + I +K +K E+ L E A+ + E+K ++
Sbjct: 440 VEAPKLKVQHKFVEEI-IEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEKEEEPE 498
Query: 319 RKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPH 378
+ +P KSP EA E +K+++ ++ + V+ D+ E K+ S E
Sbjct: 499 VEKSPVKSP-EAKEEEEGEKEEEEEGQEEEEEEDEGVKSDQAEEGGSEKEGSSEKDEGEQ 557
Query: 379 KESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKK 438
+E + E++ E EE ++K +KKT EG + + + + P K+ V K+P +
Sbjct: 558 EEEGETEAEGEGEEAEAKEEKKT------EGKVEEMAIKEEIKVEKPEKAKSPVPKSPVE 611
Query: 439 STPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGK 498
+ A+ A K ++ +K++ E P + K K++ K V D+ K
Sbjct: 612 EVKPKPEAK---AGKDEQKEEEKVEEKKEVAKESPKEE-KVEKKEEKPKD----VPDKKK 663
Query: 499 SKSGKKAKAVPSREAM-HAVVVDILKEVDFNTATLSDILRQLGTHFG------VDLMHRK 551
++S K KAV + +V V + K+ + +++ G D ++
Sbjct: 664 AESPVKEKAVEEMITITKSVKVSLEKDTKEEKPQQQEKVKEKAEEEGGSEEEVGDKSPQE 723
Query: 552 AEVKDIITDVINNMSDEEDEGEEADGDGDADKDDNG 587
++ +DI + + +E+E +E G +++ G
Sbjct: 724 SKKEDIA--INGEVEGKEEEEQETQEKGSGQEEEKG 757
>CALD_HUMAN (Q05682) Caldesmon (CDM)
Length = 793
Score = 92.4 bits (228), Expect = 3e-18
Identities = 121/513 (23%), Positives = 207/513 (39%), Gaps = 89/513 (17%)
Query: 20 DAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKD----KGGDQVEEKE 75
DA N +E + K E E E+ + + + E+ EE K G E+
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 76 EVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRG 135
+ E+E ++ DE+ E+ +EED++ E E E EE E +AE D+K+ +R
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAE-----RARLEAEERERIKAEQDKKIADERA 293
Query: 136 PKKGGKKETASEKKDPATPASERPTRERKTV--ERYSVPSPSKSAKSSGGKGLVIEKGRG 193
+ +K A E++ ER E K ER + K A + EK
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 353
Query: 194 EQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRA 253
E+ + I + KR ++ A ++ K KRN + EEK+RA
Sbjct: 354 EERQRIK----EEEKRAAEERQRARAE--EEEKAKVEEQKRN---------KQLEEKKRA 398
Query: 254 ---------KVKERID-KYVKEKLVDFCDVLNIPV---------------------SKGN 282
KV+++I+ K+V EK D L V K
Sbjct: 399 MQETKIKGEKVEQKIEGKWVNEKKAQE-DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPT 457
Query: 283 IKKEELSVKLLE-----------FLENPQATTDVLLADNEKKVKK-RTRKVTPSKSPGEA 330
KKEE+ + ++ F++ + T+V + E K + + T S+ G A
Sbjct: 458 FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRA 517
Query: 331 STETPAKKQKKTSESGK------KRKGSSDVEEDEK---------AELSDAKDESQENVA 375
S +T + E+GK +R+G ++ EE EK EL + K + +E
Sbjct: 518 SVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-- 575
Query: 376 APHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKT 435
K +++E + ++EE K +++ K+ +KE + E + +K P + K
Sbjct: 576 --RKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKP 633
Query: 436 PKKSTPKQTAAEHDSASASLSKSKQPASKKRKT 468
K TPK ++ + + + L+KS Q +S + T
Sbjct: 634 FKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 666
Score = 68.9 bits (167), Expect = 3e-11
Identities = 122/545 (22%), Positives = 207/545 (37%), Gaps = 93/545 (17%)
Query: 6 LEDHNKPPVQAEGDDA-APNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENA--- 61
LE + ++AE D A E + +A A+E+E E+ + E K AE
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 62 -EEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEE-- 118
EE+ + ++ + +E EK E + +K EE++ E+ E E + + EE++
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Query: 119 -EEEAEAEADEKVKA----------------------------KRGPKKGGKKETASEKK 149
EE+ A + K+K K+G +KG K + EK
Sbjct: 392 LEEKKRAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 150 DPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLV-IEKGRGE----QLKDIPNVAF 204
P ++ + + +++ P + KG ++ GE +LK N
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS 511
Query: 205 KLSKRKPDDNLHA--LHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKY 262
+ R D A + GKR + L+R G+ TE+EE ++ K K++
Sbjct: 512 RPGGRASVDTKEAEGAPQVEAGKRLE--ELRRRRGE------TESEEFEKLKQKQQEAAL 563
Query: 263 VKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVT 322
E+L KK E K+LE E + + AD + + ++ R++
Sbjct: 564 ELEELK---------------KKREERRKVLEEEEQRRKQEE---ADRKLREEEEKRRL- 604
Query: 323 PSKSPGEASTETPAKKQKKTSESG----KK------RKGSSDVEEDEKAELSDAKDESQE 372
K E A+K++K E G KK KGSS ++ +E+AE + +
Sbjct: 605 --KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSS-LKIEERAEFLNKSVQKSS 661
Query: 373 NVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSG-----SKAGERTKSA-KKTPV 426
V + H+ + + S E+ S + S K K + ++ KS +K V
Sbjct: 662 GVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNV 721
Query: 427 KSSKNVDKTPKKSTPKQTAAEHDSASASLSK----SKQPASKKRKTENEKPDTKGKASSK 482
SS TP K T + L+K +K PA K +K K
Sbjct: 722 FSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEK 781
Query: 483 KQTDK 487
+ DK
Sbjct: 782 QSVDK 786
Score = 63.9 bits (154), Expect = 1e-09
Identities = 93/473 (19%), Positives = 180/473 (37%), Gaps = 66/473 (13%)
Query: 52 EAVKSEAENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGE 111
E ++ EAE + D+ E E + + + K EEE + D E +
Sbjct: 16 EEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVP 75
Query: 112 EEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSV 171
+EE + + E D++ ++ ++E +K+ A ER T+ S+
Sbjct: 76 DEEAKTTTTNTQVEGDDEAAFL---ERLARREERRQKR--LQEALERQKEFDPTITDASL 130
Query: 172 PSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYN 231
PS+ ++ + EK K R+ + ++ TK+Y
Sbjct: 131 SLPSRRMQNDTAENETTEKEE------------KSESRQERYEIEETETV-----TKSYQ 173
Query: 232 LKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVK 291
W + EE ++ ++ ++ K K +G+I + ++ V
Sbjct: 174 KND---------WRDAEENKKEDKEKEEEEEEKPK-------------RGSIGENQVEVM 211
Query: 292 LLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKG 351
+ E Q T V+ N ++ K + G K +++ E + +
Sbjct: 212 VEEKTTESQEETVVMSLKN-GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERA 270
Query: 352 SSDVEE--------DEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSK 403
+ EE D+K A+ E++E AA +E + E + E++ +A ++ +
Sbjct: 271 RLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330
Query: 404 KIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQ---TAAEHDSASASLSK-SK 459
+E ++ +R K +K + + + + K++ ++ A E + A K +K
Sbjct: 331 IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNK 390
Query: 460 QPASKKR-----KTENEKPDTK--GK--ASSKKQTDKSSKALVKDQGKSKSGK 503
Q KKR K + EK + K GK K Q DK A++K QG+ K K
Sbjct: 391 QLEEKKRAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Score = 60.1 bits (144), Expect = 2e-08
Identities = 113/556 (20%), Positives = 213/556 (37%), Gaps = 76/556 (13%)
Query: 15 QAEGDDAAP------NNQETEVKGEAEAEE--KEAAPQ-EDEDASAEAVKSEAENAEEKD 65
Q EGDD A +E K EA E KE P D S + + + + AE +
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 66 KGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEE-----EE 120
++ E + E +E + K ++ D D + + E + + EEEEE+ + E
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 121 EAEAEADEK----------VKAKRG------PKKGGKKETAS---------EKKDPATPA 155
+ E +EK + K G PK+ ++E S E++D
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 156 SERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNL 215
+ER E + ER K A + E+ Q ++ + R+ +
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERA--RIEAEEKAAAQERERREAEERERMREEEKRA 324
Query: 216 HALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLN 275
+ + +A ++ I + EEK+ A+ ++RI + K +
Sbjct: 325 AEERQRIKEEEKRAAEERQRI---------KEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 276 IPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETP 335
K +++++ + +L E Q T EK +K K K E +T
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKRAMQETK----IKGEKVEQKIEGKWVNEKKAQEDKLQTA 431
Query: 336 AKK----QKKTSESGKKRKGSSDVEEDEKAELSDA-----KDESQENVAAPHKESDDDES 386
K +K T K+ K D +K E+ D K+ +E + ++ E
Sbjct: 432 VLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 491
Query: 387 KSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTP-VKSSKNVDKTPKKSTPKQT- 444
KS+ E + K T + G +A TK A+ P V++ K +++ ++ ++
Sbjct: 492 KSQNGEFMTHKLKHTENTFSR--PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 549
Query: 445 -----AAEHDSASASLSKSKQPASKKRKT-ENEKPDTKGKASSKKQTDKSSKALVKDQGK 498
+ A+ L + K+ ++RK E E+ K + + +K ++ K +K++ +
Sbjct: 550 EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 609
Query: 499 SKSGKKAKAVPSREAM 514
++A+A R+ M
Sbjct: 610 R---RRAEAAEKRQKM 622
Score = 40.8 bits (94), Expect = 0.010
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 17/293 (5%)
Query: 248 EEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLE-NPQATTDVL 306
E ++RA+ + K +E L D + + +E + +E + +A
Sbjct: 40 ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLER 99
Query: 307 LADNEKKVKKRTRKVTPSKSP-----GEASTETPAKK-QKKTSESG---KKRKGSSDVEE 357
LA E++ +KR ++ + +AS P+++ Q T+E+ K+ K S E
Sbjct: 100 LARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQER 159
Query: 358 DEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGER 417
E E Q+N +E+ ++ + EEEE++ + + V+ K
Sbjct: 160 YEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKT--- 216
Query: 418 TKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKG 477
T+S ++T V S KN + ++ PKQ + K K + E E+ +
Sbjct: 217 TESQEETVVMSLKNGQISSEE--PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEA 274
Query: 478 KASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAVVVDILKEVDFNTA 530
+ + + ++ K + D+ ++ A RE A + ++E + A
Sbjct: 275 EERERIKAEQDKK--IADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325
>IE68_SHV21 (Q01042) Immediate-early protein
Length = 407
Score = 92.0 bits (227), Expect = 4e-18
Identities = 59/152 (38%), Positives = 86/152 (55%), Gaps = 3/152 (1%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAE-AVKSEAENAE 62
E E K + E ++A +E E + EAEAEE+EA +E E+ AE A + EAE AE
Sbjct: 97 EEEEAEEKEAEEEEAEEAEEEAEEEEAE-EAEAEEEEAEEEEAEEEEAEEAEEEEAEEAE 155
Query: 63 EKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
E+ + + EE EE +E +E ++E + E E+ EE E+ E E E E E EEE EE EE
Sbjct: 156 EEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAE-EAEEEAEEAEEE 214
Query: 123 EAEADEKVKAKRGPKKGGKKETASEKKDPATP 154
EA+E +A+ ++ + E E+ P+TP
Sbjct: 215 AEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTP 246
Score = 90.5 bits (223), Expect = 1e-17
Identities = 60/176 (34%), Positives = 87/176 (49%), Gaps = 7/176 (3%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
E E + + EG + +E E E EAEEKEA +E E+A EA + EAE AE
Sbjct: 72 EERERRGEEEREGEGGEEGEGREEAE---EEEAEEKEAEEEEAEEAEEEAEEEEAEEAEA 128
Query: 64 KDKGGD----QVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEE 119
+++ + + EE EE E+E E +E EEE +EE E+ E E E E EEE EE
Sbjct: 129 EEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEA 188
Query: 120 EEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPS 175
EEAE + + +A+ ++ + E +E+ + A A E + E PS
Sbjct: 189 EEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPS 244
Score = 87.8 bits (216), Expect = 7e-17
Identities = 59/173 (34%), Positives = 86/173 (49%), Gaps = 8/173 (4%)
Query: 15 QAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEK 74
+AE ++A E E EAE E+EA +E E+A AE ++E E AEE++ + EE
Sbjct: 95 EAEEEEAEEKEAEEE---EAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEA 151
Query: 75 EEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQ-----EEEEEAEAEADEK 129
EE E+E +E + E + EEE +E +E E E E E EE E+ EE EEAE EA+E
Sbjct: 152 EEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEA 211
Query: 130 VKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSG 182
+ ++ + E A E+ + A E + Y V S + G
Sbjct: 212 EEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTPRLPHYKVVGQKPSTQPGG 264
Score = 87.4 bits (215), Expect = 9e-17
Identities = 55/159 (34%), Positives = 84/159 (52%), Gaps = 2/159 (1%)
Query: 17 EGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEE 76
EG+ +E + EAE EE E A +E E+ AE ++E E AEE++ ++ EE EE
Sbjct: 89 EGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEE 148
Query: 77 VE-KETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRG 135
E +E +E +E + EEE +EE E+ E E E E EE EE EE EEAE +E +A+
Sbjct: 149 EEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAE-EEAEEAEEAEEAEEAEEEAEEAEEE 207
Query: 136 PKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSP 174
++ ++ +E+ + A A E + E +P
Sbjct: 208 AEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTP 246
Score = 86.3 bits (212), Expect = 2e-16
Identities = 65/207 (31%), Positives = 104/207 (49%), Gaps = 10/207 (4%)
Query: 7 EDHNKPPVQAEGDDAAPNNQET-EVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKD 65
E+ + V+ EG++ +E E +G E E +E A +E+E EA + EAE AEE+
Sbjct: 60 EEQRREEVEEEGEERERRGEEEREGEGGEEGEGREEA-EEEEAEEKEAEEEEAEEAEEEA 118
Query: 66 KGGDQVEEKEEVEKETDEVKDEVKGEEEKDE-EDEDGGEGEGEGEGEEEEEQEEEEEAEA 124
+ EE EE E E +E ++E EEE +E E+E+ E E E E EE EE+ EEE EA
Sbjct: 119 ----EEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEA 174
Query: 125 EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGK 184
E E+ +A+ ++ + E A E ++ A A E + E ++ A+ +
Sbjct: 175 EEAEE-EAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEE 233
Query: 185 GLVIEKGRGEQLKDIPNVAFKLSKRKP 211
E+ G +P+ +K+ +KP
Sbjct: 234 AEEEEEEAGPSTPRLPH--YKVVGQKP 258
Score = 79.0 bits (193), Expect = 3e-14
Identities = 49/128 (38%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Query: 2 ATETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEA-VKSEAEN 60
A E E+ +AE ++A E E EAE EE E A +E E+ AE + EAE
Sbjct: 114 AEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEE 173
Query: 61 AEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEE 120
AEE ++ ++ E+ E +E +E ++E + EE+ EE E+ E E E E EE +EE E
Sbjct: 174 AEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAE-EAEEAEEEAE 232
Query: 121 EAEAEADE 128
EAE E +E
Sbjct: 233 EAEEEEEE 240
Score = 76.3 bits (186), Expect = 2e-13
Identities = 52/153 (33%), Positives = 74/153 (47%), Gaps = 6/153 (3%)
Query: 15 QAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEK 74
Q + D + Q+ + E EE E +E E E + E E EE G+ EE
Sbjct: 43 QGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEE--EREGEGGEE----GEGREEA 96
Query: 75 EEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKR 134
EE E E E ++E E E++ E+E+ E E E E EEEE EEEE EAE +E +A+
Sbjct: 97 EEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEE 156
Query: 135 GPKKGGKKETASEKKDPATPASERPTRERKTVE 167
++ +E A E+ + A A E E + E
Sbjct: 157 EAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAE 189
Score = 69.3 bits (168), Expect = 3e-11
Identities = 45/139 (32%), Positives = 70/139 (49%), Gaps = 8/139 (5%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDA-----SAEAVKSEAENA 61
E+ +AE ++A +E + E EAEE+EA + +E+A + E + EAE A
Sbjct: 129 EEEEAEEEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEA 188
Query: 62 EEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEE 121
EE ++ + EE EE E+E +E ++E + EE +E +E E E E EEEEE+
Sbjct: 189 EEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAE---EAEEEEEEAGPST 245
Query: 122 AEAEADEKVKAKRGPKKGG 140
+ V K + GG
Sbjct: 246 PRLPHYKVVGQKPSTQPGG 264
Score = 63.2 bits (152), Expect = 2e-09
Identities = 43/141 (30%), Positives = 75/141 (52%), Gaps = 12/141 (8%)
Query: 39 KEAAPQEDEDASA----EAVKSEAENAEEKDKGGDQVEEKEEVEKETD-----EVKDEVK 89
++ PQ D+D + +A +E + EE ++ G++ E + E E+E + E ++E +
Sbjct: 38 RKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEEGEGREEAE 97
Query: 90 GEE--EKDEEDEDGGEGEGEGEGEEEEEQE-EEEEAEAEADEKVKAKRGPKKGGKKETAS 146
EE EK+ E+E+ E E E E EE EE E EEEEAE E E+ +A+ ++ ++
Sbjct: 98 EEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEEE 157
Query: 147 EKKDPATPASERPTRERKTVE 167
+++ A +E E + E
Sbjct: 158 AEEEEAEEEAEEEAEEAEEAE 178
Score = 50.1 bits (118), Expect = 2e-05
Identities = 31/174 (17%), Positives = 90/174 (50%), Gaps = 9/174 (5%)
Query: 338 KQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKA 397
++++ E G++ +G + EE+E AE +A++E E +E + +E+++EEEE + +
Sbjct: 79 EEEREGEGGEEGEGREEAEEEE-AEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEE 137
Query: 398 QKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSK 457
++ + +E +A E + ++ + ++ +++ + AE ++ A ++
Sbjct: 138 AEEEEAEEAEEEEAEEAEEEAEEE-----EAEEEAEEEAEEAEEAEEEAEEEAEEAEEAE 192
Query: 458 SKQPASKK-RKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPS 510
+ A ++ + E E + + +A ++ +++ +A +++ + ++ +A PS
Sbjct: 193 EAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEA--EEEAEEAEEEEEEAGPS 244
Score = 48.1 bits (113), Expect = 6e-05
Identities = 32/188 (17%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Query: 311 EKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEE------DEKAELS 364
E++ ++R R+ + GE E +++ + E+ +K + EE +E+AE +
Sbjct: 68 EEEGEERERRGEEERE-GEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEA 126
Query: 365 DAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKT 424
+A++E E +E++++E++ EEE+ +A+++ ++ +E + +A E + A++
Sbjct: 127 EAEEEEAE-----EEEAEEEEAEEAEEEEAEEAEEEAEEEEAEEEAEEEA-EEAEEAEEE 180
Query: 425 PVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQ 484
+ ++ ++ + ++ A E + + + + A + + E + + + +++
Sbjct: 181 AEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEEEEEE 240
Query: 485 TDKSSKAL 492
S+ L
Sbjct: 241 AGPSTPRL 248
Score = 48.1 bits (113), Expect = 6e-05
Identities = 33/206 (16%), Positives = 100/206 (48%), Gaps = 9/206 (4%)
Query: 315 KKRTRKVTPSKSPGEASTE------TPAKKQKKTSESGKKRKGSSDVE-EDEKAELSDAK 367
+KR RK+ P +T T +++++ E G++R+ + E E E E + +
Sbjct: 34 RKRRRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERERRGEEEREGEGGEEGEGR 93
Query: 368 DESQENVAAPHKESDDDESK-SEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPV 426
+E++E A KE++++E++ +EEE ++ +A++ +++ E ++ E ++ ++
Sbjct: 94 EEAEEE-EAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAE 152
Query: 427 KSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTD 486
++ + ++ + ++ A E + A + + A + + E + + + ++ +
Sbjct: 153 EAEEEAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAE 212
Query: 487 KSSKALVKDQGKSKSGKKAKAVPSRE 512
+ ++ + + ++ ++A+ E
Sbjct: 213 EEAEEAEEAEEAEEAEEEAEEAEEEE 238
Score = 40.8 bits (94), Expect = 0.010
Identities = 41/202 (20%), Positives = 85/202 (41%), Gaps = 11/202 (5%)
Query: 246 ENEEKQRAKVKERIDKYVKE--KLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATT 303
E E++ A+ KE ++ +E + + + + ++EE + E E +A
Sbjct: 94 EEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEE 153
Query: 304 DVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAEL 363
A+ E++ ++ + E E A++ ++ E+ + + + + EE E E
Sbjct: 154 AEEEAE-EEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEE-EAEEA 211
Query: 364 SDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKK 423
+ +E++E A E + +E++ EEEE + K+V + ++ G K K
Sbjct: 212 EEEAEEAEEAEEAEEAEEEAEEAEEEEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLK 271
Query: 424 TP-------VKSSKNVDKTPKK 438
K ++ DK PKK
Sbjct: 272 MQPQHRSRLPKGKQSHDKVPKK 293
>TRDN_CANFA (P82179) Triadin
Length = 700
Score = 89.4 bits (220), Expect = 2e-17
Identities = 132/574 (22%), Positives = 225/574 (38%), Gaps = 122/574 (21%)
Query: 14 VQAEGDDAAPNNQETEVKGEAEAE-------EKEAAPQEDEDAS---AEAVKSEAENAEE 63
+ ++GD+ + E KGE E KE A +E++ A+ E E +E
Sbjct: 113 ISSDGDEDDDDGDEDTDKGEIEEPPLKQKEIHKEKAEKEEKPERKILAKVAHREKEKVKE 172
Query: 64 KDKGGDQVEEKEEVE-KETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
K+K + KE++E KE E K K E + E++ E +G ++E+ + A
Sbjct: 173 KEKSEKKATHKEKIEKKEKPETKTMAKEERKAKTEEKIKKEVKG-----GKQEKVKPTAA 227
Query: 123 EAEADEKVKAKRGPKKGGKKETAS----EKKD----------------------PATP-- 154
+ + +K K K+G KETA+ E+KD PA P
Sbjct: 228 KVKEVQKTPPKAKEKEG--KETAAVAKHEQKDQYAFCRYMIDMFVHGDLRPGQSPALPPP 285
Query: 155 ----ASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRK 210
+ RPT T+E K+ K + EK ++ D + A + K++
Sbjct: 286 LPTVQASRPTPASPTLEGKEEEEKKKAEKKVTSETKKKEKEDVKKKSD-KDTAIDVEKKE 344
Query: 211 PDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQR--AKVKERIDKYVKEKLV 268
P KA K+ + + +EK+ K K ++++
Sbjct: 345 PG---------------KAPETKQGTIKVVAQAAAKKDEKKEDSKKTKTPVEEH------ 383
Query: 269 DFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPG 328
P K KKE +++E +++ A +EK+VK +T + S
Sbjct: 384 --------PKGKKQEKKE-------KYVEPAKSSKKEHSAPSEKQVKAKTERAKEETSAA 428
Query: 329 EASTETPAKKQKKTS----------ESGKKRKGSSD----VEEDEKAELSDAK---DESQ 371
P KK++KT+ +SGK S D +++DEK +D + Q
Sbjct: 429 STKKAVPGKKEEKTTKTVEQEIRKEKSGKTSTASKDKEPEIKKDEKMPKADKEVKPKPPQ 488
Query: 372 ENVAAPHKESDDDESKSEEEEDKSKAQK-----KTSKKIVKEGSGSKAGERTKSAKKTPV 426
V K + +++ E+D +K +K K +K+VK+ ++ K+ K P
Sbjct: 489 SQVKKEEKSESQVKKEAKPEQDIAKPEKTVSHGKPEEKVVKQVKATEKAAIEKTVKPKPA 548
Query: 427 KSSKNVDK---TPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKK 483
K +++ +K T K PK T+ E + S K+ K K EK + K K
Sbjct: 549 KKAEHQEKESPTIKTDKPKPTSKETPEVTES---GKKKIEKSEKESKEKAEMKHLKEEKV 605
Query: 484 QTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAV 517
T K S ++ +K+ K A+ SRE + V
Sbjct: 606 STRKES---LQSHNVTKAEKPARV--SREDLEDV 634
Score = 75.1 bits (183), Expect = 5e-13
Identities = 117/485 (24%), Positives = 189/485 (38%), Gaps = 96/485 (19%)
Query: 75 EEVEKETDEV-------KDEVKGEEEKDEEDEDGGEGEGEGEGEE---------EEEQEE 118
+ VE+ TD V D + + ++D D+DG E +GE EE +E+ E+
Sbjct: 93 DAVEETTDWVYGFFSLLSDIISSDGDED--DDDGDEDTDKGEIEEPPLKQKEIHKEKAEK 150
Query: 119 EEEAEAE--------ADEKVKAK-RGPKKGGKKETASEKKDPATPASERPTRERKTVERY 169
EE+ E + EKVK K + KK KE +K+ P T + R+ KT E+
Sbjct: 151 EEKPERKILAKVAHREKEKVKEKEKSEKKATHKEKIEKKEKPETKTMAKEERKAKTEEKI 210
Query: 170 SVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKA 229
K K GGK + K ++K++ K +++ GK T A
Sbjct: 211 -----KKEVK--GGKQEKV-KPTAAKVKEVQKTPPKAKEKE-------------GKETAA 249
Query: 230 YNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKL-VDFCDVLNIPVSKGNIKKEEL 288
V ++ Q A + ID +V L L P+ +
Sbjct: 250 -------------VAKHEQKDQYAFCRYMIDMFVHGDLRPGQSPALPPPLPTVQASRPTP 296
Query: 289 SVKLLEFLENPQ------ATTDVLLADNEKKVKKRTRKVT----PSKSPGEAS------- 331
+ LE E + T ++ VKK++ K T K PG+A
Sbjct: 297 ASPTLEGKEEEEKKKAEKKVTSETKKKEKEDVKKKSDKDTAIDVEKKEPGKAPETKQGTI 356
Query: 332 ---TETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKS 388
+ AKK +K +S +K + VEE K + K E +E P K S + S
Sbjct: 357 KVVAQAAAKKDEKKEDS---KKTKTPVEEHPKGK----KQEKKEKYVEPAKSSKKEHSAP 409
Query: 389 EEEEDKSK---AQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTA 445
E++ K+K A+++TS K+ K E+T + ++ K+ KT S K+
Sbjct: 410 SEKQVKAKTERAKEETSAASTKKAVPGKKEEKTTKTVEQEIRKEKS-GKTSTASKDKEPE 468
Query: 446 AEHDSASASLSKS---KQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSG 502
+ D K K P S+ +K E + K +A ++ K K + + + K
Sbjct: 469 IKKDEKMPKADKEVKPKPPQSQVKKEEKSESQVKKEAKPEQDIAKPEKTVSHGKPEEKVV 528
Query: 503 KKAKA 507
K+ KA
Sbjct: 529 KQVKA 533
Score = 68.2 bits (165), Expect = 6e-11
Identities = 107/432 (24%), Positives = 180/432 (40%), Gaps = 77/432 (17%)
Query: 12 PPVQAEGDD-AAPNNQETEVKGEAEAEEK---EAAPQEDEDASAEAVKSEAENAEEKDKG 67
P VQA A+P + E + + +AE+K E +E ED ++ K A + E+K+ G
Sbjct: 287 PTVQASRPTPASPTLEGKEEEEKKKAEKKVTSETKKKEKEDVKKKSDKDTAIDVEKKEPG 346
Query: 68 GDQVEEKE---EVEKETDEVKDEVKGEEEKDE---EDEDGGEGEGEGEGEEEEEQEEEEE 121
E K+ +V + KDE K + +K + E+ G+ + + E E + ++E
Sbjct: 347 -KAPETKQGTIKVVAQAAAKKDEKKEDSKKTKTPVEEHPKGKKQEKKEKYVEPAKSSKKE 405
Query: 122 AEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSS 181
A ++++VKAK + K+ET++ A P ++ + KTVE+ + K
Sbjct: 406 HSAPSEKQVKAK---TERAKEETSAASTKKAVP-GKKEEKTTKTVEQ-------EIRKEK 454
Query: 182 GGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSG 241
GK K + ++K ++ P K K K Q
Sbjct: 455 SGKTSTASKDKEPEIKK--------DEKMP-------------KADKEVKPKPPQSQVKK 493
Query: 242 FVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA 301
+E++ K+ AK ++ I K K VS G K EE VK ++ E +A
Sbjct: 494 EEKSESQVKKEAKPEQDIAKPEK------------TVSHG--KPEEKVVKQVKATE--KA 537
Query: 302 TTDVLLADNEKKVKKRTRKVTP---SKSPGEASTETPAKKQKKTSESGKKRKGSSDVEED 358
+ + K + K +P + P S ETP + +ESGKK+ S+ E
Sbjct: 538 AIEKTVKPKPAKKAEHQEKESPTIKTDKPKPTSKETP-----EVTESGKKKIEKSEKESK 592
Query: 359 EKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGS-KAGER 417
EKAE+ K+E K S ES K++ + S++ +++ S S KA E
Sbjct: 593 EKAEMKHLKEE---------KVSTRKESLQSHNVTKAEKPARVSREDLEDVSASKKAKEE 643
Query: 418 TKSAKKTPVKSS 429
+ T + S
Sbjct: 644 AEDVSSTKRQKS 655
Score = 46.6 bits (109), Expect = 2e-04
Identities = 73/343 (21%), Positives = 141/343 (40%), Gaps = 28/343 (8%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDE-DASAEAVKSEAENAEEKDKGGD 69
K PV+ +E V+ ++++ +AP E + A E K E A K
Sbjct: 377 KTPVEEHPKGKKQEKKEKYVEPAKSSKKEHSAPSEKQVKAKTERAKEETSAASTKKAVPG 436
Query: 70 QVEEK------EEVEKE-TDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEA 122
+ EEK +E+ KE + + K +E + ++DE + + E + + + Q ++EE
Sbjct: 437 KKEEKTTKTVEQEIRKEKSGKTSTASKDKEPEIKKDEKMPKADKEVKPKPPQSQVKKEE- 495
Query: 123 EAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSG 182
++E+ K +AK ++T S K + E+ +E+ P P+K A+
Sbjct: 496 KSESQVKKEAKPEQDIAKPEKTVSHGKPEEKVVKQVKATEKAAIEKTVKPKPAKKAEHQE 555
Query: 183 GKGLVIEKGRGEQL-KDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSG 241
+ I+ + + K+ P V + K+K + + K +K +++ +
Sbjct: 556 KESPTIKTDKPKPTSKETPEVT-ESGKKKIEKS---------EKESKEKAEMKHLKEEK- 604
Query: 242 FVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQA 301
V T E Q + K K V D+ ++ SK K+E V + ++P +
Sbjct: 605 -VSTRKESLQ----SHNVTKAEKPARVSREDLEDVSASK-KAKEEAEDVSSTKRQKSPIS 658
Query: 302 TTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSE 344
+ D + VTP+ PGE+S + + QK+ +
Sbjct: 659 FFQCVYLDGYNGYGFQF-PVTPAYRPGESSGQPSSPGQKQQGQ 700
Score = 44.3 bits (103), Expect = 0.001
Identities = 57/249 (22%), Positives = 98/249 (38%), Gaps = 8/249 (3%)
Query: 283 IKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKT 342
+K++E+ + E E P+ +A EK+ K K + K+ + E KK+K
Sbjct: 138 LKQKEIHKEKAEKEEKPERKILAKVAHREKEKVKEKEK-SEKKATHKEKIE---KKEKPE 193
Query: 343 SESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTS 402
+++ K + + EE K E+ K E + AA KE K++E+E K A
Sbjct: 194 TKTMAKEERKAKTEEKIKKEVKGGKQEKVKPTAAKVKEVQKTPPKAKEKEGKETAAVAKH 253
Query: 403 KKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPA 462
++ + + P +S P + T A + + K+ A
Sbjct: 254 EQKDQYAFCRYMIDMFVHGDLRPGQSPALPPPLPTVQASRPTPAS-PTLEGKEEEEKKKA 312
Query: 463 SKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKAVPSREAMHAVVVDIL 522
KK +E +K K K KK++DK + V+ + K+ + + A A D
Sbjct: 313 EKKVTSETKK---KEKEDVKKKSDKDTAIDVEKKEPGKAPETKQGTIKVVAQAAAKKDEK 369
Query: 523 KEVDFNTAT 531
KE T T
Sbjct: 370 KEDSKKTKT 378
>NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 kDa
protein) (140 kDa nucleolar phosphoprotein) (Nopp140)
(Nucleolar and coiled-body phosphoprotein 1)
Length = 704
Score = 84.0 bits (206), Expect = 1e-15
Identities = 121/550 (22%), Positives = 199/550 (36%), Gaps = 101/550 (18%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQ 70
K + D++ ++ E E K + + K AAP + A K+ A+ A E +
Sbjct: 77 KAKKETSSSDSSEDSSEEEDKAQVPTQ-KAAAPAKRASLPQHAGKAAAK-ASESSSSEES 134
Query: 71 VEEKEEVEKETDEVKDEVKGEEEK----DEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEA 126
EE+EE +K+ V+ + + K + + E E + E+E Q ++ +A A A
Sbjct: 135 SEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDSSSEDEAPQTQKPKAAATA 194
Query: 127 DEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGL 186
K T ++ K PA P P + + S S S+ SS
Sbjct: 195 -------------AKAPTKAQTKAPAKPGP--PAKAQPKAANGKAGSSSSSSSSSSSDDS 239
Query: 187 VIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE 246
EK A L K P + A + K T A K + + S +E
Sbjct: 240 EEEK----------KAAAPLKKTAPKKQVVAKAPV---KVTAAPTQKSSSSEDSS---SE 283
Query: 247 NEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKL-LEFLENPQATTDV 305
EE+Q+ +K++ Y ++P ++ K+ + + + Q
Sbjct: 284 EEEEQKKPMKKKAGPYS-----------SVPPPSVSLSKKSVGAQSPKKAAAQTQPADSS 332
Query: 306 LLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDE------ 359
+ E K TP+K+ + PA +KK S SD EDE
Sbjct: 333 ADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDS--SDSDSSEDEAPAKPV 390
Query: 360 ---KAELSDA----KDESQENVAAPHK--------ESDDDESKSEEEEDKSKAQKKTSKK 404
K+ LS K + + VA P + +S +S S EEE S ++ T K
Sbjct: 391 SATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKS 450
Query: 405 IV---------------------------KEGSGSKAGERTKSAKKTPVKSSKNVDKTPK 437
+ + S + E K+ K P K PK
Sbjct: 451 VTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKKAAGAAVPK 510
Query: 438 KSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASS--KKQTDKSSKALVKD 495
+ K+ AAE S+S+S S + KK K++ GKA+ Q K+ K ++
Sbjct: 511 PTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKESEEE 570
Query: 496 QGKSKSGKKA 505
+ ++ KKA
Sbjct: 571 EEDTEQNKKA 580
Score = 68.9 bits (167), Expect = 3e-11
Identities = 81/313 (25%), Positives = 123/313 (38%), Gaps = 60/313 (19%)
Query: 250 KQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLL-EFLENPQATTDVLLA 308
K AK E + + D PV + +K + +V+ + E+ ++ +D
Sbjct: 120 KAAAKASESSSSEESSEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDSSSE 179
Query: 309 DNEKKVKKRTRKVTPSKSPGEASTETPAK------------KQKKTSESGKKRKGSSDVE 356
D + +K T +K+P +A T+ PAK K S S SSD
Sbjct: 180 DEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDS 239
Query: 357 EDEK---AELSDAKDESQENVAAP--------HKESDDDESKSEEEEDKSKAQKK----- 400
E+EK A L + Q AP K S ++S SEEEE++ K KK
Sbjct: 240 EEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPY 299
Query: 401 ---------TSKKIVKEGSGSKAGERTKSA-----------------KKTPVKSSKNVDK 434
SKK V S KA +T+ A KKTP K+ V K
Sbjct: 300 SSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTV--VSK 357
Query: 435 TPKKSTPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVK 494
TP K P + AE S S+ S+ A K + + P +K + K ++KA+
Sbjct: 358 TPAKPAPVKKKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPK---PPAAKAVAT 414
Query: 495 DQGKSKSGKKAKA 507
+ + SG+K ++
Sbjct: 415 PKQPAGSGQKPQS 427
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/255 (23%), Positives = 103/255 (39%), Gaps = 14/255 (5%)
Query: 277 PVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPA 336
P+ G ++ +LS +F + AT A + + K T + S A
Sbjct: 16 PLVLGFLRDNQLSEVASKFAKATGATQQDANASSLLDIYSFWLKSTKAPKVKLQSNGPVA 75
Query: 337 KKQKKTSESGKKRKGSSDVEEDEKAELSDAK----------DESQENVAAPHKESDDDES 386
KK KK + S + SS EE++KA++ K + AA ES E
Sbjct: 76 KKAKKETSSSDSSEDSS--EEEDKAQVPTQKAAAPAKRASLPQHAGKAAAKASESSSSEE 133
Query: 387 KSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAA 446
SEEEE+K K +K +K VK + + K+ S + D+ P+ PK AA
Sbjct: 134 SSEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDSSSEDEAPQTQKPK--AA 191
Query: 447 EHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
+ + + +++K PA + + GKA S + SS + ++ K + K
Sbjct: 192 ATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKK 251
Query: 507 AVPSREAMHAVVVDI 521
P ++ + V +
Sbjct: 252 TAPKKQVVAKAPVKV 266
Score = 61.6 bits (148), Expect = 6e-09
Identities = 102/522 (19%), Positives = 190/522 (35%), Gaps = 54/522 (10%)
Query: 15 QAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEK 74
Q + AA + K + +A K P + + +A + ++ D EEK
Sbjct: 184 QTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEK 243
Query: 75 EEVE--KETDEVKDEV-KGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEA------- 124
+ K+T K V K + + EEEEEQ++ + +A
Sbjct: 244 KAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVP 303
Query: 125 ----EADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSV-------PS 173
+K + PKK + ++ ++ S+ + E K +V P+
Sbjct: 304 PPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPA 363
Query: 174 PSKSAKSSGGKGLVIEKGRGEQ-LKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNL 232
P K S + E K + LSK A ++ K+
Sbjct: 364 PVKKKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQ 423
Query: 233 KRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKL 292
K + + +EE+ + +E K V P ++ K +
Sbjct: 424 KPQSRKADS---SSSEEESSSSEEEATKKSV-----------TTPKARVTAK----AAPS 465
Query: 293 LEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGE-----ASTETPAKKQKKTSESGK 347
L + P+A D +D+E + +K TP K P + A+ P +K +ES
Sbjct: 466 LPAKQAPRAGGDSS-SDSESSSSEEEKK-TPPKPPAKKKAAGAAVPKPTPVKKAAAESSS 523
Query: 348 KRKGSSDVEEDEKAE---LSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKK 404
S D E+EK + + K ++ + P ++ +SEEEE+ ++ KK +
Sbjct: 524 SSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKESEEEEEDTEQNKKAAG- 582
Query: 405 IVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASK 464
K GSG K + ++A + SK V + PK+ E ++S ++
Sbjct: 583 -TKPGSGKKR-KHNETADEAATPQSKKVKLQTPNTFPKRKKGEKRASSPFRRVREEEIEV 640
Query: 465 KRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAK 506
+ + D K + ++ +++++ L +GKS +K K
Sbjct: 641 DSRVADNSFDAK-RGAAGDWGERANQVLKFTKGKSFRHEKTK 681
Score = 41.6 bits (96), Expect = 0.006
Identities = 33/141 (23%), Positives = 58/141 (40%), Gaps = 13/141 (9%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKG-GD 69
KPP + + AA K AE+ ++ ++ + + KS+A + K G
Sbjct: 496 KPPAKKKAAGAAVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGV 555
Query: 70 QVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEK 129
+ + KE++E EE+D E G G G++ + E +EA +K
Sbjct: 556 PASQNGKAGKESEE--------EEEDTEQNKKAAGTKPGSGKKRKHNETADEAATPQSKK 607
Query: 130 VKAKR----GPKKGGKKETAS 146
VK + +K G+K +S
Sbjct: 608 VKLQTPNTFPKRKKGEKRASS 628
Score = 37.0 bits (84), Expect = 0.15
Identities = 34/163 (20%), Positives = 64/163 (38%), Gaps = 25/163 (15%)
Query: 11 KPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQ 70
K V A+ + P Q G++ ++ + ++ +E++ K+ + +K G
Sbjct: 455 KARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEK-------KTPPKPPAKKKAAGAA 507
Query: 71 VEEKEEVEKETDEVKDEVKGEEEKDEEDE-----------DGGEGEGEGEGEE----EEE 115
V + V+K E E+ EE++ G+ G + +E
Sbjct: 508 VPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKES 567
Query: 116 QEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASER 158
+EEEE+ E K A P G K++ + ATP S++
Sbjct: 568 EEEEEDTE---QNKKAAGTKPGSGKKRKHNETADEAATPQSKK 607
>GARP_PLAFF (P13816) Glutamic acid-rich protein precursor
Length = 678
Score = 82.0 bits (201), Expect = 4e-15
Identities = 48/128 (37%), Positives = 70/128 (54%), Gaps = 8/128 (6%)
Query: 14 VQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEE 73
VQ E + + +E E E E EE+E +E+E+ E + E E +E ++ D EE
Sbjct: 558 VQEESKEVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEE 617
Query: 74 KEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAK 133
E+ +E ++ +E EE+ DEED+D E E E EE+EE+EEEEE E+E K K
Sbjct: 618 DEDDAEEDEDDAEEDDDEEDDDEEDDD----EDEDEDEEDEEEEEEEEEESEK----KIK 669
Query: 134 RGPKKGGK 141
R +K K
Sbjct: 670 RNLRKNAK 677
Score = 81.3 bits (199), Expect = 7e-15
Identities = 86/453 (18%), Positives = 187/453 (40%), Gaps = 32/453 (7%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
ET D + +D ++Q+ E+ ++KE +E E E ++ + + EE
Sbjct: 230 ETSNDTKDNDKENISEDKKEDHQQEEML--KTLDKKERKQKEKEMKEQEKIEKKKKKQEE 287
Query: 64 KDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE 123
K+K + E K++ +KE + + E+K +++ ++E + E E + + ++E +E ++ +
Sbjct: 288 KEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPD 347
Query: 124 AEADE--------------KVKAKRGPKKGGKKE---TASEKKDPATPASERPTRERKTV 166
++E V K+G KE E K+ E E K
Sbjct: 348 QTSEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEHKKE 407
Query: 167 ERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKR 226
E S SK K G K +KG+ ++ K + D++ + I +
Sbjct: 408 EHKSKEHKSKGKKDKGKK----DKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEIINLEDK 463
Query: 227 TKAYNL-----KRNIGQFSGFVWTENEE---KQRAKVKERIDKYVKEKLVDFCDVLNIPV 278
R + Q + E E+ ++KV+E+ + ++E+L+ +N+
Sbjct: 464 EACEEQHITVESRPLSQPQCKLIDEPEQLTLMDKSKVEEK-NLSIQEQLIGTIGRVNVVP 522
Query: 279 SKGNIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKK 338
+ N KK+ ++ E + + + K+V++ +++V + E E ++
Sbjct: 523 RRDNHKKKMAKIEEAELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEE 582
Query: 339 QKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQ 398
+++ E ++ + + EE+E+ + + ++ E +E +DD + ++EED +
Sbjct: 583 EEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEEDDDEEDDDEED 642
Query: 399 KKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKN 431
+ +E + E +S KK KN
Sbjct: 643 DDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKN 675
Score = 79.3 bits (194), Expect = 3e-14
Identities = 96/464 (20%), Positives = 186/464 (39%), Gaps = 38/464 (8%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDK 66
EDH + + D +E E+K + + E+K+ +E E E + + E E K K
Sbjct: 249 EDHQQEEMLKTLDKKERKQKEKEMKEQEKIEKKKKKQEEKEKKKQEKERKKQEKKERKQK 308
Query: 67 GGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEA 126
+ ++K+ +EKE + +++ K +++ D+E+E+ + + + EE E
Sbjct: 309 EKEMKKQKK-IEKERKKKEEKEKKKKKHDKENEETMQ---QPDQTSEETNNEIMVPLPSP 364
Query: 127 DEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGL 186
V K+G KE E K+ E E K E SK KS G K
Sbjct: 365 LTDVTTPEEHKEGEHKE--EEHKEGEHKEGEHKEEEHKEEEHKKEEHKSKEHKSKGKK-- 420
Query: 187 VIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKR---TKAYNLKRNIGQFSGFV 243
+KG+ ++ K K+ K H + +++ + + NL+
Sbjct: 421 --DKGKKDKGKHKKAKKEKVKK-------HVVKNVIEDEDKDGVEIINLEDK-------- 463
Query: 244 WTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATT 303
E E+Q V+ R + KL+D + L + + K ++++ LS++ + +
Sbjct: 464 --EACEEQHITVESRPLSQPQCKLIDEPEQLTL-MDKSKVEEKNLSIQE-QLIGTIGRVN 519
Query: 304 DVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAEL 363
V DN KK + + K + K++ K ES + ++ S +V+EDE+
Sbjct: 520 VVPRRDNHKKKMAKIEEAELQKQ------KHVDKEEDKKEESKEVQEESKEVQEDEEEVE 573
Query: 364 SDAKDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKK 423
D ++E +E +E +++E + EEEE++ ++ ++ ++ E
Sbjct: 574 EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAEEDEDDAEEDD 633
Query: 424 TPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQPASKKRK 467
+ D + + E + S K K+ K K
Sbjct: 634 DEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKNAK 677
Score = 70.1 bits (170), Expect = 2e-11
Identities = 44/160 (27%), Positives = 86/160 (53%), Gaps = 6/160 (3%)
Query: 7 EDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDK 66
++H K + E +A Q+ K E + EE + +E ++ + + E + EE+++
Sbjct: 525 DNHKKKMAKIE--EAELQKQKHVDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEE 582
Query: 67 GGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEA 126
++ EE+EE E+E +E ++E EE++DEEDED E E E + EE+E+ EE++ E +
Sbjct: 583 EEEEEEEEEEEEEEEEEEEEE---EEDEDEEDEDDAE-EDEDDAEEDEDDAEEDDDEEDD 638
Query: 127 DEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTV 166
DE+ + + +E E+++ + +R R+ +
Sbjct: 639 DEEDDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKNAKI 678
Score = 67.0 bits (162), Expect = 1e-10
Identities = 119/625 (19%), Positives = 240/625 (38%), Gaps = 75/625 (12%)
Query: 3 TETL---EDHNKPPVQAEGDDAAPN-NQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEA 58
+ETL E K V +D N + E+ + +D + S + K +
Sbjct: 65 SETLLKEEKDEKDDVPTTSNDNLKNAHNNNEISSSTDPTNIINVNDKDNENSVDKKKDKK 124
Query: 59 ENAEEKDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEE 118
E +KDK + ++ ++ +K+ E K + + + +KD++ ++ E + + + +
Sbjct: 125 EKKHKKDKKEKKEKKDKKEKKDKKEKKHKKEKKHKKDKKKKENSEVMSLYKTGQHKPKNA 184
Query: 119 EEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSA 178
E E DE++ ++ G +S P R + SV S
Sbjct: 185 TEHGEENLDEEMVSEINNNAQGGLLLSS-------PYQYREQGGCGIIS--SVHETSNDT 235
Query: 179 KSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKR------TKAYNL 232
K + + + +K Q +++ K +++ + + I K+ K
Sbjct: 236 KDNDKENISEDKKEDHQQEEMLKTLDKKERKQKEKEMKEQEKIEKKKKKQEEKEKKKQEK 295
Query: 233 KRNIGQFSGFVWTENEEKQRAKV-KERIDKYVKEKLVDFCDVLN-IPVSKGNIKKEELSV 290
+R + E E K++ K+ KER K KEK D N + + + EE +
Sbjct: 296 ERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQTSEETNN 355
Query: 291 KLLEFLENPQATTDVLLADNEKKVK-KRTRKVTPSKSPGEASTETPAKKQKKTSE----- 344
+++ L +P TDV + K+ + K GE E +++ K E
Sbjct: 356 EIMVPLPSP--LTDVTTPEEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEHKKEEHKSKE 413
Query: 345 ---SGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESD------DDESKSEEEE--D 393
GKK KG D + +KA+ K +NV + +D+ EE+
Sbjct: 414 HKSKGKKDKGKKDKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEIINLEDKEACEEQHITV 473
Query: 394 KSKAQKKTSKKIVKEG------SGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAE 447
+S+ + K++ E SK E+ S ++ + + V+ P++ K+ A+
Sbjct: 474 ESRPLSQPQCKLIDEPEQLTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRRDNHKKKMAK 533
Query: 448 HDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA 507
+ A L K K K E++K ++K K+ + + + +D+ + + ++ +
Sbjct: 534 IE--EAELQKQKH----VDKEEDKKEESKEVQEESKEVQEDEEEVEEDEEEEEEEEEEEE 587
Query: 508 VPSREAMHAVVVDILKEVDFNTATLSDILRQLGTHFGVDLMHRKAEVKDIITDVINNMSD 567
E + +E D E +D + ++ +
Sbjct: 588 EEEEEEEEEEEEEEEEEED-----------------------EDEEDEDDAEEDEDDAEE 624
Query: 568 EEDEGEEADGDGDADKDDNGDDDDE 592
+ED+ EE D + D D++D+ +D+DE
Sbjct: 625 DEDDAEEDDDEEDDDEEDDDEDEDE 649
Score = 66.2 bits (160), Expect = 2e-10
Identities = 122/634 (19%), Positives = 254/634 (39%), Gaps = 75/634 (11%)
Query: 10 NKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE------ 63
N+ ++ DD N ++E + E +EK+ P D A + ++
Sbjct: 51 NETELEKNKDD----NSKSETLLKEEKDEKDDVPTTSNDNLKNAHNNNEISSSTDPTNII 106
Query: 64 --KDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDE-EDEDGGEGEGEGEGEEEEEQEEEE 120
DK + +K++ +KE KD+ + +E+KD+ E +D E + + E + +++++++E
Sbjct: 107 NVNDKDNENSVDKKKDKKEKKHKKDKKEKKEKKDKKEKKDKKEKKHKKEKKHKKDKKKKE 166
Query: 121 EAEAEADEKV---KAKRGPKKGGK---KETASEKKDPATP----ASERPTRERKTVERYS 170
+E + K K K + G + +E SE + A +S RE+ S
Sbjct: 167 NSEVMSLYKTGQHKPKNATEHGEENLDEEMVSEINNNAQGGLLLSSPYQYREQGGCGIIS 226
Query: 171 -VPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRT-- 227
V S K + + + +K Q +++ K +++ + + I K+
Sbjct: 227 SVHETSNDTKDNDKENISEDKKEDHQQEEMLKTLDKKERKQKEKEMKEQEKIEKKKKKQE 286
Query: 228 ----KAYNLKRNIGQFSGFVWTENEEKQRAKV-KERIDKYVKEKLVDFCDVLNIP-VSKG 281
K +R + E E K++ K+ KER K KEK D N + +
Sbjct: 287 EKEKKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQP 346
Query: 282 NIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSK-SPGEASTETPAKKQK 340
+ EE + +++ L +P TDV + K+ + + + + GE E +++
Sbjct: 347 DQTSEETNNEIMVPLPSP--LTDVTTPEEHKEGEHKEEEHKEGEHKEGEHKEEEHKEEEH 404
Query: 341 KTSE--------SGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESD------DDES 386
K E GKK KG D + +KA+ K +NV + +D+
Sbjct: 405 KKEEHKSKEHKSKGKKDKGKKDKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEIINLEDKE 464
Query: 387 KSEEEED--KSKAQKKTSKKIVKEGSG------SKAGERTKSAKKTPVKSSKNVDKTPKK 438
EE+ +S+ + K++ E SK E+ S ++ + + V+ P++
Sbjct: 465 ACEEQHITVESRPLSQPQCKLIDEPEQLTLMDKSKVEEKNLSIQEQLIGTIGRVNVVPRR 524
Query: 439 STPKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGK 498
K+ A+ + A K K E++K ++K K+ + + + +D+ +
Sbjct: 525 DNHKKKMAKIEEAELQKQKHVD------KEEDKKEESKEVQEESKEVQEDEEEVEEDEEE 578
Query: 499 SKSGKKAKAVPSREAMHAVVVDILKEVDFNTATLSDILRQLGTHFGVDLMHRKAEVKDII 558
+ ++ + E + +E D + D + + ++
Sbjct: 579 EEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEED------------EDDAEEDE 626
Query: 559 TDVINNMSDEEDEGEEADGDGDADKDDNGDDDDE 592
D + +E+D+ E+ D D D D++D ++++E
Sbjct: 627 DDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEE 660
Score = 65.5 bits (158), Expect = 4e-10
Identities = 77/475 (16%), Positives = 203/475 (42%), Gaps = 52/475 (10%)
Query: 48 DASAEAVKSEAENAEEKDKGGDQVEE------KEEVEKETDEVKDEVKGEEEKDEEDEDG 101
+ S + ++ EN E K Q EE K+E +++ E+K++ K E++K +++E
Sbjct: 230 ETSNDTKDNDKENISEDKKEDHQQEEMLKTLDKKERKQKEKEMKEQEKIEKKKKKQEEKE 289
Query: 102 GEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPATPASERPTR 161
+ + + ++E+++ +++E E + +K++ +R K+ +K+ K+ +
Sbjct: 290 KKKQEKERKKQEKKERKQKEKEMKKQKKIEKERKKKEEKEKKKKKHDKENEETMQQPDQT 349
Query: 162 ERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSI 221
+T VP PS + + + + E+ K+ + K + K +++ H
Sbjct: 350 SEETNNEIMVPLPSPLTDVTTPEEHKEGEHKEEEHKEGEH---KEGEHKEEEHKEEEH-- 404
Query: 222 LFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAKVKERIDKYVKEKLV-----DFCDVLNI 276
+ + + K + + +++ K + KE++ K+V + ++ D +++N+
Sbjct: 405 ----KKEEHKSKEHKSKGKKDKGKKDKGKHKKAKKEKVKKHVVKNVIEDEDKDGVEIINL 460
Query: 277 PVSKG------NIKKEELSVKLLEFLENPQATTDVLLADNEKKVKKRTRKV------TPS 324
+ ++ LS + ++ P+ T + ++ KV+++ + T
Sbjct: 461 EDKEACEEQHITVESRPLSQPQCKLIDEPEQLTLM----DKSKVEEKNLSIQEQLIGTIG 516
Query: 325 KSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDD 384
+ + KK K E+ +++ D EED+K E + ++ES+E
Sbjct: 517 RVNVVPRRDNHKKKMAKIEEAELQKQKHVDKEEDKKEESKEVQEESKE------------ 564
Query: 385 ESKSEEEEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQT 444
+ +EEE + +++ + +E + E + ++ + ++ + +
Sbjct: 565 -VQEDEEEVEEDEEEEEEE---EEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDED 620
Query: 445 AAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKS 499
AE D A ++ ++ E+E D + + +++ ++S K + ++ K+
Sbjct: 621 DAEEDEDDAEEDDDEEDDDEEDDDEDEDEDEEDEEEEEEEEEESEKKIKRNLRKN 675
Score = 57.8 bits (138), Expect = 8e-08
Identities = 38/127 (29%), Positives = 63/127 (48%), Gaps = 12/127 (9%)
Query: 4 ETLEDHNKPPVQAEGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEE 63
E ED + E ++ +E E + E E EE+E +EDED E E E+ E
Sbjct: 564 EVQEDEEEVEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEDEEDEDDAEEDEDDAE 623
Query: 64 KDKGGDQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAE 123
+D+ + ++ EE + E D+ +DE + EE+ +EE+E EEEEE E++ +
Sbjct: 624 EDEDDAEEDDDEEDDDEEDDDEDEDEDEED-EEEEE-----------EEEEESEKKIKRN 671
Query: 124 AEADEKV 130
+ K+
Sbjct: 672 LRKNAKI 678
>CYL1_HUMAN (P35663) Cylicin I (Multiple-band polypeptide I)
(Fragment)
Length = 598
Score = 80.9 bits (198), Expect = 9e-15
Identities = 100/489 (20%), Positives = 199/489 (40%), Gaps = 48/489 (9%)
Query: 57 EAENAEEKDKGGDQVEEKEEVEK----ETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEE 112
+AE + KD+ G +K+ +K T+ ++ E+ K + + D + E E+
Sbjct: 59 KAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQ 118
Query: 113 EEEQEEEEEAEAEADEKVKAKRGPKKGGKKETASEKKDPAT--PASERPTRERKTVERYS 170
++ + E E+ + + KK++ + KK P ++ K + +
Sbjct: 119 SKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSN 178
Query: 171 VPSPSKSAKSSGGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAY 230
P +++S ++ G+ D ++ F R N +S+ + K TK
Sbjct: 179 DPISEICSENSLNVDFLMLVGQS----DDESINFDAWLRNYSQNNSKNYSLKYTKYTKK- 233
Query: 231 NLKRNIGQFSGFVWTENEE--KQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEEL 288
+ K+N + S ++++ K KVK+ + K K+K V D + G+ K E
Sbjct: 234 DTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKK-DTESTDAESGDSKDERK 292
Query: 289 SVKLLEFLENPQATTDVLLADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKK 348
K L D++KK K+ + T ++S ++ KK S++ K
Sbjct: 293 DTK---------KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK 343
Query: 349 RKG---------------SSDVEEDEKAELSDAKDESQENVAAPHKESD-DDESKSEEEE 392
+K S + ++DEK + D+K +++++V + +D D E K + ++
Sbjct: 344 KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 403
Query: 393 DKS--KAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPK---KSTPKQTAAE 447
K K KK SKK K+ K E T+ +K K K K K K +
Sbjct: 404 GKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKD 463
Query: 448 HDSASASLSKSKQP----ASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGK 503
+S A +S + ++K + ++ E ++ K +KK+ D+S + + K
Sbjct: 464 TESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESK 523
Query: 504 KAKAVPSRE 512
+ + S++
Sbjct: 524 RGFRMSSKK 532
Score = 63.9 bits (154), Expect = 1e-09
Identities = 102/463 (22%), Positives = 171/463 (36%), Gaps = 77/463 (16%)
Query: 85 KDEVKGEEEKDEEDEDGGE----------GEGEGEGEEEEEQEEEEEAEAEADEKVKAKR 134
K +K E K +DE GG G E ++ EE+ + + EAD+
Sbjct: 54 KTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSS 113
Query: 135 GPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKGRGE 194
+ KK +S + +P + S+ ++ ++ SK++K + + L + +
Sbjct: 114 HENEQSKKSKSSSETNPESQNSKTVSKNCSQKDK----KDSKNSKKTNTEFLHTKNNPKK 169
Query: 195 QLKDIPNVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTENEEKQRAK 254
LK +S+ +++L+ +L G+ + W N + +K
Sbjct: 170 DLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDE--------SINFDAWLRNYSQNNSK 221
Query: 255 -VKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENPQATTDVLLADNEKK 313
+ KY K+ +K N KK + E ++ A D +K
Sbjct: 222 NYSLKYTKYTKKD------------TKKNAKKSSDA----ESEDSKDAKKDSKKV--KKN 263
Query: 314 VKKRTRKVTPSKSPGEASTET--------PAKKQKKTSESGKKRKGSSDVEEDEKAELSD 365
VKK +K K E+ KK KK + K+K + E E D
Sbjct: 264 VKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGD 323
Query: 366 AKDESQENVAAPHKESDDDESK-------------------SEEEEDKSKAQKKT-SKKI 405
AKD ++ +DD+ K S+++E K K KT +KK
Sbjct: 324 AKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKS 383
Query: 406 VKEGSGSKAGER-----TKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSAS-ASLSKSK 459
VK S + +K KK K K+ K KK K+ A + S L K K
Sbjct: 384 VKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDK 443
Query: 460 QPASKKR--KTENEKPDTKGKASSKKQTDKSSKALVKDQGKSK 500
+ + +K+ K + +K K S+ + D+SSK K K K
Sbjct: 444 KHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIK 486
Score = 61.2 bits (147), Expect = 7e-09
Identities = 67/260 (25%), Positives = 112/260 (42%), Gaps = 24/260 (9%)
Query: 332 TETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDAKDESQENVAAPHKESDDDESKSEEE 391
T+ KK K S S + + S D ++D K + K + ++ ES D ES ++
Sbjct: 231 TKKDTKKNAKKS-SDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKD 289
Query: 392 E------DKSKAQKKTSKKIVK---EGSGSKAGER--TKSAKKTPVKSSKNVDKTPKKST 440
E DK K +K KK K E + +++G+ ++ + K+SKN D KK
Sbjct: 290 ERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD---KKKD 346
Query: 441 PKQTAAEHDSASASLSKSKQPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSK 500
K+ DS S SK Q KK K +++ + K + ++ TD S + +G SK
Sbjct: 347 AKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADS----EPKGDSK 402
Query: 501 SGKKAKAVPSREAMHAVVVDILKEVDFNTATLSDI-LRQLGTHFGVDLMHRKAEVKDIIT 559
GKK + +++ K+ +T SD+ L++ H +K KDI
Sbjct: 403 KGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH----SKEKKGSKKDIKK 458
Query: 560 DVINNMSDEEDEGEEADGDG 579
D + + E +E+ G
Sbjct: 459 DARKDTESTDAEFDESSKTG 478
Score = 56.2 bits (134), Expect = 2e-07
Identities = 36/149 (24%), Positives = 77/149 (51%), Gaps = 9/149 (6%)
Query: 18 GDDAAPNNQETEVKGEAEAEEKEAAPQE---DEDASAEAVKSEAENAEEKDKGGDQVEEK 74
GD N +K ++ ++K+ ++ D+ +E E++ E+KDK + + K
Sbjct: 322 GDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNK 381
Query: 75 EEV--EKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEAD---EK 129
+ V ++E+ + E KG+ +K ++DE G+ + + + ++++ ++ E E E+D +K
Sbjct: 382 KSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKK 441
Query: 130 VKAKRGPKKGGKKETASE-KKDPATPASE 157
K KKG KK+ + +KD + +E
Sbjct: 442 DKKHSKEKKGSKKDIKKDARKDTESTDAE 470
Score = 53.1 bits (126), Expect = 2e-06
Identities = 96/469 (20%), Positives = 181/469 (38%), Gaps = 54/469 (11%)
Query: 27 ETEVKGEAEAEE-KEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEEVE---KETD 82
+T +K E E+ K++ + + ++ K+ ++N +KDK + +K E + +
Sbjct: 107 KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 166
Query: 83 EVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADEKVKAKRGPKKGGKK 142
KD + + D E E + Q ++E +A + ++ K K
Sbjct: 167 PKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLK 226
Query: 143 ETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSSGGKGLVIEKG--RGEQLKDIP 200
T KKD A + E + SK AK K ++K + ++ KD+
Sbjct: 227 YTKYTKKDTKKNAKKSSDAESED---------SKDAKKDSKK---VKKNVKKDDKKKDVK 274
Query: 201 NVAFKLSKRKPDDNLHALHSILFGKRTKAYNLKRNIGQFSGFVWTE--------NEEKQR 252
D + K+ K + K++ ++ TE N+ +
Sbjct: 275 KDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL 334
Query: 253 AKVKERIDKYVKEKLVDFC----DVLNIPVSKGNIKKEELSVKL--LEFLENPQATTDVL 306
K + DK K + F L S+ + KK++ K + ++N + +TD
Sbjct: 335 KKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTD-- 392
Query: 307 LADNEKKVKKRTRKVTPSKSPGEASTETPAKKQKKTSESGKKRKGSSDVEEDEKAELSDA 366
AD+E K + K K ++ + K KK +ES + SD+E + + S
Sbjct: 393 -ADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEME---SDLELKKDKKHSKE 448
Query: 367 KDESQENVAAPHKESDDDESKSEEEEDKSKAQKKTSKKI-----------VKEGSGSKAG 415
K S++++ ++ D ES E ++ SK KTS KI K G+ K
Sbjct: 449 KKGSKKDIKKDARK--DTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKID 506
Query: 416 E---RTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDSASASLSKSKQP 461
E + ++K ++S + + KK+T + + + S+ K P
Sbjct: 507 ESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPP 555
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/181 (23%), Positives = 80/181 (43%), Gaps = 25/181 (13%)
Query: 19 DDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGD-QVEEKEEV 77
+D + ++E KG+++ +K+ + + + K +NAE + D ++++ ++
Sbjct: 386 NDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 445
Query: 78 EKETDEVKDEVKGEEEKDEEDEDGGEGEG-----------EGEGEEEEEQEEEEEAEAEA 126
KE K ++K + KD E D E +G E EE + A+ +
Sbjct: 446 SKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKI 505
Query: 127 DEK-----------VKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVE--RYSVPS 173
DE +++KRG + KK T +EK + A+ P+RE+ + S+PS
Sbjct: 506 DESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPLPACEPSLPS 565
Query: 174 P 174
P
Sbjct: 566 P 566
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/173 (21%), Positives = 78/173 (44%), Gaps = 9/173 (5%)
Query: 16 AEGDDAAPNNQETE-----VKGEAEAEEKEAAPQEDEDASAEA--VKSEAENAEEKDKGG 68
AE D+ ++T+ +K + + ++ + P+ + S +A ++++ N ++ K
Sbjct: 282 AESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKND 341
Query: 69 DQVEEKEEVEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEEEAEAEADE 128
D+ ++ +++ TD + E +KDE+ + + + +E+ + ++E + D
Sbjct: 342 DKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDS 401
Query: 129 KVKAKRGPKKGGKKETASEKKDPATPASERPTRERKTVERYSVPSPSKSAKSS 181
K K K+ KKG K +KK A +E T +E SK K S
Sbjct: 402 K-KGKKDEKKGKKDSKKDDKKKDAKKNAE-STEMESDLELKKDKKHSKEKKGS 452
Score = 48.5 bits (114), Expect = 5e-05
Identities = 65/326 (19%), Positives = 129/326 (38%), Gaps = 32/326 (9%)
Query: 17 EGDDAAPNNQETEVKGEAEAEEKEAAPQEDEDASAEAVKSEAENAEEKDKGGDQVEEKEE 76
+ DA + + K + ++ + +D + ++AE+ + KD+ D ++K++
Sbjct: 241 KSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKK 300
Query: 77 VEKETDEVKDEVKGEEEKDEEDEDGGEGEGEGEGEEEEEQEEEE-------------EAE 123
++K+ D+ KD K E D E D + + ++ + +++ E+E
Sbjct: 301 LKKD-DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESE 359
Query: 124 AEADEKVKAKRGPKKGGKKETASEKK--DPATPASERPTRERKTVERYSVPSPSKSAKSS 181
E+ E K ++ KK K + K + +T A P + K ++ S K
Sbjct: 360 LESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDD 419
Query: 182 GGKGLVIEKGRGEQLKDIPNVAFKLSKRKPDDNLHALHSILFGKR--TKAYNLKRNIGQF 239
K K E + ++ K K+ + + I R T++ + + +
Sbjct: 420 KKKD---AKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSK 476
Query: 240 SGFVWTENEEKQRAKVKERIDKYVKEKLVDFCDVLNIPVSKGNIKKEELSVKLLEFLENP 299
+GF + + + +E + K +K +D D + N K E L K F +
Sbjct: 477 TGFKTSTKIKGSDTESEESLYKPGAKKKIDESD-----GTSANSKMEGLESK-RGFRMSS 530
Query: 300 QATTDVLLADNEKKVKKRTRKVTPSK 325
+ TT NEK K T +V PS+
Sbjct: 531 KKTT-----FNEKGEKASTGRVPPSR 551
Score = 37.4 bits (85), Expect = 0.11
Identities = 42/210 (20%), Positives = 83/210 (39%), Gaps = 12/210 (5%)
Query: 391 EEDKSKAQKKTSKKIVKEGSGSKAGERTKSAKKTPVKSSKNVDKTPKKSTPKQTAAEHDS 450
E KSK +K + +K+ S K G + + + K + TP +++ E++
Sbjct: 61 EYKKSKDEKGGTP--LKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQ 118
Query: 451 ASASLSKSK-QPASKKRKTENEKPDTKGKASSKKQTDKSSKALVKDQGKSKSGKKAKA-- 507
+ S S S+ P S+ KT ++ K K SK +++ L K K++K
Sbjct: 119 SKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSN 178
Query: 508 -----VPSREAMHAVVVDILKEVDFNTATLSDILRQLGTH--FGVDLMHRKAEVKDIITD 560
+ S +++ + ++ + D + LR + L + K KD +
Sbjct: 179 DPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKN 238
Query: 561 VINNMSDEEDEGEEADGDGDADKDDNGDDD 590
+ E ++ ++A D K + DD
Sbjct: 239 AKKSSDAESEDSKDAKKDSKKVKKNVKKDD 268
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.296 0.120 0.306
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,287,897
Number of Sequences: 164201
Number of extensions: 3765141
Number of successful extensions: 102323
Number of sequences better than 10.0: 3674
Number of HSP's better than 10.0 without gapping: 1633
Number of HSP's successfully gapped in prelim test: 2116
Number of HSP's that attempted gapping in prelim test: 24217
Number of HSP's gapped (non-prelim): 28843
length of query: 592
length of database: 59,974,054
effective HSP length: 116
effective length of query: 476
effective length of database: 40,926,738
effective search space: 19481127288
effective search space used: 19481127288
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 69 (31.2 bits)
Lotus: description of TM0063.6