BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0040.3
         (441 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

KMLS_CHICK (P11799) Myosin light chain kinase, smooth muscle and...    40  0.012
RAV1_ARATH (Q9ZWM9) DNA-binding protein RAV1                           38  0.059
MMGL_MOUSE (P49300) Macrophage asialoglycoprotein-binding protei...    36  0.17
PHPA_PLACH (Q02752) Acidic phosphoprotein precursor (50 kDa anti...    35  0.29
KMLS_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC...    33  1.1
NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa neur...    33  1.9
GYRB_RICCN (Q92H87) DNA gyrase subunit B (EC 5.99.1.3)                 33  1.9
NIA_NEUCR (P08619) Nitrate reductase [NADPH] (EC 1.7.1.3) (NR)         32  2.5
NXF1_MOUSE (Q99JX7) Nuclear RNA export factor 1 (Tip associating...    32  3.3
NUCL_MESAU (P08199) Nucleolin (Protein C23)                            32  3.3
CCAF_MOUSE (Q9JIS7) Voltage-dependent L-type calcium channel alp...    32  3.3
ARFU_ARATH (Q9C8N9) Putative auxin response factor 21                  32  3.3
ARFQ_ARATH (Q84WU6) Auxin response factor 17                           32  3.3
ARFP_ARATH (Q93YR9) Auxin response factor 16                           32  3.3
NXF1_RAT (O88984) Nuclear RNA export factor 1 (Tip associating p...    32  4.3
LECI_HUMAN (P07307) Asialoglycoprotein receptor 2 (Hepatic lecti...    32  4.3
JPH2_MOUSE (Q9ET78) Junctophilin 2 (Junctophilin type 2) (JP-2)        32  4.3
DYNA_CHICK (P35458) Dynactin 1 (150 kDa dynein-associated polype...    32  4.3
CHD4_MOUSE (Q6PDQ2) Chromodomain helicase-DNA-binding protein 4 ...    32  4.3
RLUF_ECOL6 (Q8FB47) Ribosomal large subunit pseudouridine syntha...    31  5.6

>KMLS_CHICK (P11799) Myosin light chain kinase, smooth muscle and
            non-muscle isozymes (EC 2.7.1.117) (MLCK) [Contains:
            Telokin]
          Length = 1906

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 30/97 (30%), Positives = 44/97 (44%), Gaps = 7/97 (7%)

Query: 214  NENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKSPELRKRKKVQV 273
            +E + + H P Q+    +L KK  PK+P+    P  K      + V     L  +KK   
Sbjct: 951  SEEERKVHAPQQVDFRSVLAKKGTPKTPLPEKVPPPKPAVTDFRSV-----LGAKKKPPA 1005

Query: 274  EGGEPSSLGPHFTAQGEARKYTPKNPSFTVSLKPVIK 310
            E G  S+  P+  A  EA+  TP   S   + KPV+K
Sbjct: 1006 ENGSASTPAPNARAGSEAQNATPN--SEAPAPKPVVK 1040


>RAV1_ARATH (Q9ZWM9) DNA-binding protein RAV1
          Length = 344

 Score = 37.7 bits (86), Expect = 0.059
 Identities = 20/65 (30%), Positives = 31/65 (46%), Gaps = 6/65 (9%)

Query: 337 IEENLWPVEFIYYPEHGSGKLSKGWIQFAKESKLVGGDVCVFELINKDEENPVLEVHIFK 396
           +   +W   + Y+    S  L+KGW +F KE  L  GDV  F   N  ++       ++ 
Sbjct: 233 VNGKVWRFRYSYWNSSQSYVLTKGWSRFVKEKNLRAGDVVSFSRSNGQDQ------QLYI 286

Query: 397 GFKSR 401
           G+KSR
Sbjct: 287 GWKSR 291


>MMGL_MOUSE (P49300) Macrophage asialoglycoprotein-binding protein 1
           (M-ASGP-BP) (Macrophage
           galactose/N-acetylgalactosamine-specific lectin) (MMGL)
          Length = 304

 Score = 36.2 bits (82), Expect = 0.17
 Identities = 16/45 (35%), Positives = 27/45 (59%), Gaps = 4/45 (8%)

Query: 157 IHWSKHD-SYFWF---QKGWKEFVKYYSLDHGHLVLFEFKDASHF 197
           +HW++H+ S +WF   +K W E  KY  L++ HLV+    +  +F
Sbjct: 175 LHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNF 219


>PHPA_PLACH (Q02752) Acidic phosphoprotein precursor (50 kDa
           antigen)
          Length = 441

 Score = 35.4 bits (80), Expect = 0.29
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 204 NSTLEIEYPSNENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRP----CKKLRTGKSKDV 259
           N   E     NEN+GE+   +  G++    KK K KS   +        KK +  + K  
Sbjct: 345 NENQENVKKGNENEGEQKGNENEGEQKGKKKKAKEKSKKKVKNKPTMTTKKKKKKEKKKK 404

Query: 260 GKSPELRKRKKVQVE 274
            K  E +K KKV+VE
Sbjct: 405 KKEKEKKKEKKVKVE 419


>KMLS_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC
           2.7.1.117) (MLCK) [Contains: Telokin]
          Length = 1147

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 28/95 (29%), Positives = 44/95 (45%), Gaps = 7/95 (7%)

Query: 214 NENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKSPELRKRKKVQV 273
           +E + + H+P Q+    +L KK  PK+P+    P  K  T   + V     L  +KK+  
Sbjct: 17  SEEERKVHSPQQVDFRSVLAKKGTPKTPVPEKAPPPKPATPDFRSV-----LGSKKKLPA 71

Query: 274 EGGEPSSLGPHFTAQGEARKYTPKNPSFTVSLKPV 308
           E G  ++   +  A  E+ K     P  + SLKPV
Sbjct: 72  ENGSSNAEALNVKAT-ESPKLVGNAP-LSGSLKPV 104


>NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa
           neurofilament protein) (Neurofilament heavy polypeptide)
           (NF-H)
          Length = 1026

 Score = 32.7 bits (73), Expect = 1.9
 Identities = 30/137 (21%), Positives = 54/137 (38%), Gaps = 3/137 (2%)

Query: 206 TLEIEYPSNENQGEEHN---PDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKS 262
           TL+++ P  +   +E      D+  ++   P K + KSP     P K+      K++ K 
Sbjct: 764 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 823

Query: 263 PELRKRKKVQVEGGEPSSLGPHFTAQGEARKYTPKNPSFTVSLKPVIKLAYRPPVPISFI 322
            E++   K + +  E     P   A+ E    TPK      S K        P   +   
Sbjct: 824 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 883

Query: 323 REYLNEKKQTIKLKIEE 339
           +E   EK +  K++ ++
Sbjct: 884 KEPAVEKPKESKVEAKK 900


>GYRB_RICCN (Q92H87) DNA gyrase subunit B (EC 5.99.1.3)
          Length = 807

 Score = 32.7 bits (73), Expect = 1.9
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 149 APDNTSWEIHWSKHDS---YFWFQKGWKEFVKYYSLDHGHLVLFEFKDASHFGVHIFDNS 205
           +PD T+WE+   KH++   +F F +G KE      L    L  FEF   S F + IFD  
Sbjct: 650 SPDKTNWEV--LKHENKIEFFRFSRGLKESK---ILLKEQLESFEFVQISKFALTIFDIF 704

Query: 206 TLEIEYPSNENQGEEHNPDQIGDEIL 231
           + +++      + +   P Q+ + I+
Sbjct: 705 SKQLKLIVKSQEFDILTPSQLLNTII 730


>NIA_NEUCR (P08619) Nitrate reductase [NADPH] (EC 1.7.1.3) (NR)
          Length = 982

 Score = 32.3 bits (72), Expect = 2.5
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 15/125 (12%)

Query: 203 DNST-----LEIEYPSNENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSK 257
           DNST     +   + SN N      P  I    L     KP  P  L  P  +L T    
Sbjct: 78  DNSTTLETSVNYSHSSNTNTNTSCPPSPITSSSL-----KPAYP--LPPPSTRLTTILPT 130

Query: 258 DVGKSPE--LRKRKKVQVEGGEPSSLGPHFTAQGEARKYTPKNPSFTVSLKPVIKLAYRP 315
           D+ K+P+  +R  + +++ G  P ++ P  TA  E    TP+N  +  +  P+      P
Sbjct: 131 DL-KTPDHLIRDPRLIRLTGSHPFNVEPPLTALFEHGFLTPQNLHYVRNHGPIPSSVATP 189

Query: 316 PVPIS 320
           P  I+
Sbjct: 190 PATIN 194


>NXF1_MOUSE (Q99JX7) Nuclear RNA export factor 1 (Tip associating
           protein) (Tip-associated protein) (mRNA export factor
           TAP)
          Length = 618

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 9/92 (9%)

Query: 4   VSCFVQKLPNAFTRKYSGDNMSNPVFLKPLDNISWEINWSKQ--------DSDIWLQNVW 55
           +S  VQK PN  T   SG+ +     L  +  +  E  W  +        D   ++  + 
Sbjct: 282 MSSIVQKAPNLKTLNLSGNELKTERELDKIKGLKLEELWLDRNPMCDNFGDQSSYISAIR 341

Query: 56  EEFVKLYYLDQGHMVWHLVLFEFKGPSKFEVC 87
           E F KL  LD GH +   + F+ + P+    C
Sbjct: 342 ERFPKLLRLD-GHELPPPISFDVEAPTMLPPC 372


>NUCL_MESAU (P08199) Nucleolin (Protein C23)
          Length = 713

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 6/76 (7%)

Query: 208 EIEYPSNENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKSPELRK 267
           E+E  S + +  E   D  G+E+++P+K   K   + + P KK+   ++K V        
Sbjct: 22  EVEEDSEDEEMSEEEDDSSGEEVVIPQK---KGKKATATPAKKVVVSQTKKVAVP---TP 75

Query: 268 RKKVQVEGGEPSSLGP 283
            KK  V  G+ ++  P
Sbjct: 76  AKKAAVTPGKKAAATP 91


>CCAF_MOUSE (Q9JIS7) Voltage-dependent L-type calcium channel alpha-1F
            subunit (Voltage-gated calcium channel alpha subunit
            Cav1.4)
          Length = 1985

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 22/69 (31%), Positives = 35/69 (49%), Gaps = 6/69 (8%)

Query: 215  ENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKK-----LRTGKSKDVGKSPELRKRK 269
            E +  E+NP+   D I    +++  S +S+S P K+     L TG S D G +P  R+  
Sbjct: 1659 EEEEAENNPEPYKDSIDSQPQSRWNSRISVSLPVKEKLPDSLSTGPSDDDGLAPNSRQPS 1718

Query: 270  KVQVEGGEP 278
             +Q  G +P
Sbjct: 1719 VIQA-GSQP 1726


>ARFU_ARATH (Q9C8N9) Putative auxin response factor 21
          Length = 606

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 15/49 (30%), Positives = 23/49 (46%)

Query: 330 KQTIKLKIEENLWPVEFIYYPEHGSGKLSKGWIQFAKESKLVGGDVCVF 378
           ++ + + + +N W     Y        L+ GW +F    KLV GDV VF
Sbjct: 164 QEILAIDLHDNQWRFRHNYRGTPQRHSLTTGWNEFITSKKLVKGDVIVF 212


>ARFQ_ARATH (Q84WU6) Auxin response factor 17
          Length = 585

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 21/82 (25%), Positives = 32/82 (38%), Gaps = 12/82 (14%)

Query: 304 SLKPVIKLAYRPPVPISFIREYLNEKKQTIKLKIEENLWPVEFIYYPEHGSGKLSKGWIQ 363
           S+ P++     PPV   ++ +            I   +W    IY        L+ GW +
Sbjct: 143 SVFPLLNFQIDPPVQKLYVTD------------IHGAVWDFRHIYRGTPRRHLLTTGWSK 190

Query: 364 FAKESKLVGGDVCVFELINKDE 385
           F    KL+ GD  VF   + DE
Sbjct: 191 FVNSKKLIAGDSVVFMRKSADE 212


>ARFP_ARATH (Q93YR9) Auxin response factor 16
          Length = 670

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 331 QTIKLK-IEENLWPVEFIYYPEHGSGKLSKGWIQFAKESKLVGGDVCVF 378
           QTI  K +  ++W    IY        L+ GW  F  + KLV GD  VF
Sbjct: 158 QTILAKDVHGDVWKFRHIYRGTPRRHLLTTGWSNFVNQKKLVAGDSIVF 206


>NXF1_RAT (O88984) Nuclear RNA export factor 1 (Tip associating
           protein) (Tip-associated protein) (mRNA export factor
           TAP)
          Length = 618

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 9/92 (9%)

Query: 4   VSCFVQKLPNAFTRKYSGDNMSNPVFLKPLDNISWEINWSKQ--------DSDIWLQNVW 55
           +S  VQK PN      SG+ + +   L  +  +  E  W  +        D   ++  + 
Sbjct: 282 MSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIR 341

Query: 56  EEFVKLYYLDQGHMVWHLVLFEFKGPSKFEVC 87
           E F KL  LD GH +   + F+ + P+    C
Sbjct: 342 ERFPKLLRLD-GHELPPPIAFDVEAPTMLPPC 372


>LECI_HUMAN (P07307) Asialoglycoprotein receptor 2 (Hepatic lectin
           H2) (ASGP-R) (ASGPR)
          Length = 311

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 4/49 (8%)

Query: 153 TSWEIHWSKHD-SYFWFQ---KGWKEFVKYYSLDHGHLVLFEFKDASHF 197
           T   ++W +H  S +WF    K W E  KY  L++ HLV+    +   F
Sbjct: 175 TCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKF 223


>JPH2_MOUSE (Q9ET78) Junctophilin 2 (Junctophilin type 2) (JP-2)
          Length = 696

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 23/71 (32%), Positives = 32/71 (44%), Gaps = 6/71 (8%)

Query: 212 PSNENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKSPELRKRKKV 271
           P     G E+   ++  EIL        S   L  P + L TG  +   +SP+L +R+  
Sbjct: 418 PDFYQPGPEYQKRRLLQEIL------ENSESLLEPPERGLGTGLPERPRESPQLHERETP 471

Query: 272 QVEGGEPSSLG 282
           Q EGG PS  G
Sbjct: 472 QPEGGPPSPAG 482


>DYNA_CHICK (P35458) Dynactin 1 (150 kDa dynein-associated
           polypeptide) (DP-150) (DAP-150) (p150-glued)
          Length = 1224

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 27/108 (25%), Positives = 41/108 (37%), Gaps = 9/108 (8%)

Query: 233 PKKTKPKSPMSLSRPCKKLRTGKSKDVGKSPELRKRKKVQVEGGEPSSLGPHFTAQGEAR 292
           PKKT  + P     P     +G +   G +            GGE SS  P   AQ    
Sbjct: 136 PKKTTARRPKPTRTPTSAPSSGTAGPSGSA---------SASGGEMSSSEPSTPAQTPLV 186

Query: 293 KYTPKNPSFTVSLKPVIKLAYRPPVPISFIREYLNEKKQTIKLKIEEN 340
                +PS T  + P++    +    +      L EK +T+K+K  E+
Sbjct: 187 APVIPSPSLTSPVAPMVPSPTKEEENLRSQVRDLEEKLETLKIKRNED 234


>CHD4_MOUSE (Q6PDQ2) Chromodomain helicase-DNA-binding protein 4
           (CHD-4)
          Length = 1915

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 35/138 (25%)

Query: 204 NSTLEIEYPSNENQGEEHNPDQIGDEILLPKKTKPKSPMSLSRPCKKLRTGKSKDVGKSP 263
           N++L   +P NE   +E   +   +   L KK KPK P                   + P
Sbjct: 25  NNSLPPPHPENEEDPDEDLSE--AETPKLKKKKKPKKP-------------------RDP 63

Query: 264 ELRKRKKVQVEGGEPSSLGPHFTAQGE--ARKYTPKNPSFTVSLKPVIKLAYRPPVPISF 321
           ++ K K+ + E G+ S  GP F  + E  A +   +   +T   K   KL  +       
Sbjct: 64  KIPKSKRQKKELGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPK------- 116

Query: 322 IREYLNEKKQTIKLKIEE 339
                 EKK   K K EE
Sbjct: 117 -----KEKKSKSKRKEEE 129


>RLUF_ECOL6 (Q8FB47) Ribosomal large subunit pseudouridine synthase
           F (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 290

 Score = 31.2 bits (69), Expect = 5.6
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 245 SRPCKKLRTGKSKDVGKSPELRKRKKVQVEGGEPSSLGPHFTAQGEARK 293
           S   K     K K VG    + K +K   +GG P+S G  FT+ G  +K
Sbjct: 240 SSEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKK 288


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.138    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,129,164
Number of Sequences: 164201
Number of extensions: 2716580
Number of successful extensions: 5659
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5638
Number of HSP's gapped (non-prelim): 45
length of query: 441
length of database: 59,974,054
effective HSP length: 113
effective length of query: 328
effective length of database: 41,419,341
effective search space: 13585543848
effective search space used: 13585543848
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)