BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0034b.2
         (494 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

GRLF_CANFA (P83509) Glucocorticoid receptor DNA binding factor 1...    34  0.99
Y553_HUMAN (Q9UKJ3) Hypothetical protein KIAA0553                      33  1.3
SHK1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains prot...    32  2.9
KRP1_SCHPO (Q09175) Dibasic processing endoprotease precursor (E...    32  2.9
HLH4_CAEEL (P34555) Helix-loop-helix protein 4                         32  2.9
GRLF_MOUSE (Q91YM2) Glucocorticoid receptor DNA binding factor 1...    32  2.9
GLI3_XENLA (Q91660) Zinc finger protein GLI3 (Neural specific DN...    32  2.9
RLM1_YEAST (Q12224) Transcription factor RLM1                          32  4.9
GAG_SFV3L (P27400) Gag polyprotein (Core polyprotein)                  32  4.9
YKU2_YEAST (P36042) Hypothetical 21.2 kDa protein in TOR2-MNN4 i...    31  6.4
GRLF_HUMAN (Q9NRY4) Glucocorticoid receptor DNA binding factor 1...    31  6.4
NFC2_MOUSE (Q60591) Nuclear factor of activated T-cells, cytopla...    31  8.4
ATX2_MOUSE (O70305) Ataxin-2 (Spinocerebellar ataxia type 2 prot...    31  8.4

>GRLF_CANFA (P83509) Glucocorticoid receptor DNA binding factor 1 (Rho
            GAP p190A) (p190-A)
          Length = 1500

 Score = 33.9 bits (76), Expect = 0.99
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 12/71 (16%)

Query: 66   TSISLFLRNRHFPFHNRPIVRSNSPLHATHLPKTIMTSNLPHASNTRHPSSFSP------ 119
            T I LF++   F FHNRPI   + P  AT    + + S +P  ++T   S  SP      
Sbjct: 1424 TIIELFIQQCPFFFHNRPI---SEPPGATPSSPSAVASTVPFLTSTPVTSQPSPPQSPPP 1480

Query: 120  ---SPIKTLLP 127
               SP++ LLP
Sbjct: 1481 TPQSPMQALLP 1491


>Y553_HUMAN (Q9UKJ3) Hypothetical protein KIAA0553
          Length = 1089

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/139 (25%), Positives = 61/139 (42%), Gaps = 28/139 (20%)

Query: 52   LYPPHVAAPRDASVTSISLF---LRNRH-------FPFHNRPIVRSNSPLHATHLPKTIM 101
            L P H+  P  AS TSI+     +   H          H  P  +  + +H  H+P+  +
Sbjct: 943  LQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVH--HIPQPHL 1000

Query: 102  T----SNLPHASNTRHPSSFSPSPIKTLLP----HSHPFL------RPLFTSLIAYQTPS 147
            T    S+L H+    HP++F  S    ++P    H  PF         L+ +L+A +  +
Sbjct: 1001 TPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGPFTFHPVPHAALYPTLLAPRPAA 1060

Query: 148  AHFRSGAVAYHPFRYPLFT 166
            A   + A+  HP  +P+F+
Sbjct: 1061 A--AATALHLHPLLHPIFS 1077


>SHK1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains protein 1
            (Shank1) (Somatostatin receptor interacting protein)
            (SSTR interacting protein) (SSTRIP)
          Length = 2161

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 20/53 (37%), Positives = 25/53 (46%), Gaps = 11/53 (20%)

Query: 200  PTSPNHSSSSSGSD-----------PDATAAGGLRLEAPEIPPYRLKTYATLP 241
            PTSP  S + +G+D           P A  AGG     PE+PP  L T + LP
Sbjct: 1782 PTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASCLP 1834


>KRP1_SCHPO (Q09175) Dibasic processing endoprotease precursor (EC
           3.4.21.-) (KEX2-related protease)
          Length = 709

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 81  NRPIVRSNSPLHATHLPKTIMTSNLPHASNTRHPSSFSPSPIKTLLPHSHPFLRPLFTSL 140
           N  +  S++ L  T    T  T      S T  P+S S  PI T+LP + P L P +  +
Sbjct: 615 NSDLTNSSTLLSPTSTSFTSYT-----VSATATPTSTSHIPIPTVLPPTQPVLEPSYREI 669

Query: 141 IAYQT 145
           +A+ T
Sbjct: 670 VAFIT 674


>HLH4_CAEEL (P34555) Helix-loop-helix protein 4
          Length = 205

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 18/51 (35%), Positives = 25/51 (48%), Gaps = 2/51 (3%)

Query: 212 SDPDATAAGGLRLEAPEIPPYRLKTYATLPLPVQIAPTHEAIDQPSIFQNS 262
           S PD   +  +R  AP +P  R +TY   P+    AP H  +D  S F +S
Sbjct: 90  SKPDTVISQPIRPLAPVLP--RHETYLPAPIAATCAPDHSLVDYRSTFASS 138


>GRLF_MOUSE (Q91YM2) Glucocorticoid receptor DNA binding factor 1
            (Fragment)
          Length = 1337

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 66   TSISLFLRNRHFPFHNRPIVRSNSPLHATHLPKTIMTSNLPHASNTRHPSSFSPSPIKTL 125
            T I LF++   F F+NRPI   + P  A     + M   +P  ++T  P++  PSP ++ 
Sbjct: 1261 TIIELFIQQCPFFFYNRPI---SEPPGAAPGSPSAMAPTVPFLTST--PATSQPSPPQSP 1315

Query: 126  LPHSHPFLRPLFTS 139
             P     ++PL +S
Sbjct: 1316 PPTPQSPMQPLLSS 1329


>GLI3_XENLA (Q91660) Zinc finger protein GLI3 (Neural specific DNA
           binding protein XGLI3) (XGLI-3)
          Length = 1569

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 33/145 (22%)

Query: 34  PYSGEAFRAFP-------YFKTLLNLYPP-HVAAPRDASVTSISLFLRNRHFPFHNRPIV 85
           PY G  F   P       ++++ L+L+P  H   P DA         R+    +H  P  
Sbjct: 103 PYRGTVFAMDPRNGYIDPHYRSDLDLFPAFHPPVPIDA---------RHHEGRYHYEP-- 151

Query: 86  RSNSPLHATHLPKTIMTS----NLP--HASNTRHPSSFSPSPIKTLLPHSHPFLRPLFTS 139
              +P+   H+P  + +S    +LP    S  R+P+S S SP        HP++ P    
Sbjct: 152 ---TPIPPLHVPTALASSPTYPDLPFFRISPHRNPASASDSPFSP----PHPYISPYMDY 204

Query: 140 LIA-YQTPSAHFRSGAVAYHPFRYP 163
           + + + +PS    S A    P   P
Sbjct: 205 IRSLHSSPSLSMISAARGLSPTDVP 229


>RLM1_YEAST (Q12224) Transcription factor RLM1
          Length = 676

 Score = 31.6 bits (70), Expect = 4.9
 Identities = 16/81 (19%), Positives = 40/81 (48%)

Query: 199 NPTSPNHSSSSSGSDPDATAAGGLRLEAPEIPPYRLKTYATLPLPVQIAPTHEAIDQPSI 258
           N + P HSS  + + P ++++    ++ P++P ++  ++   P P+ I+P   +    + 
Sbjct: 213 NISRPYHSSMYNLNQPSSSSSSPSTMDFPKLPSFQNSSFNGRPPPISISPNKFSKPFTNA 272

Query: 259 FQNSDLIVQFVNSLGGLSNDD 279
              +      +N+ G  +ND+
Sbjct: 273 SSRTPKQEHKINNSGSNNNDN 293


>GAG_SFV3L (P27400) Gag polyprotein (Core polyprotein)
          Length = 643

 Score = 31.6 bits (70), Expect = 4.9
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 11/82 (13%)

Query: 193 LLKMASNPTSPNHSSSSSGSDPDATAAGGLRLEAPEIPPYRLKTYATLPLPVQIAPTHEA 252
           L ++A NP  P  S  S GS P            P  PP  L +  +LP PV   P  + 
Sbjct: 227 LSRVAYNPFLPGSSDGSGGSIP----------VQPSAPPAVLPSLPSLPAPVS-QPIIQY 275

Query: 253 IDQPSIFQNSDLIVQFVNSLGG 274
           + QP +     + +Q + ++ G
Sbjct: 276 VAQPPVPAPQAIPIQHIRAVTG 297


>YKU2_YEAST (P36042) Hypothetical 21.2 kDa protein in TOR2-MNN4
           intergenic region
          Length = 193

 Score = 31.2 bits (69), Expect = 6.4
 Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 9/66 (13%)

Query: 83  PIVRSNSPLHA-----THLPKTIMTSNLPHASNTRHPSSFSPSPIKT---LLPHSHPFLR 134
           P++RS+S LH       HL  +     LP +S+   PSSFSP P  +   LLP     L 
Sbjct: 80  PLLRSSSFLHLHSSYFLHLHSSSFLL-LPASSSLLLPSSFSPLPPASSFLLLPSFSSLLL 138

Query: 135 PLFTSL 140
           P F+SL
Sbjct: 139 PSFSSL 144


>GRLF_HUMAN (Q9NRY4) Glucocorticoid receptor DNA binding factor 1
            (Glucocorticoid receptor repression factor 1) (GRF-1)
            (Rho GAP p190A) (p190-A)
          Length = 1513

 Score = 31.2 bits (69), Expect = 6.4
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 5/82 (6%)

Query: 66   TSISLFLRNRHFPFHNRPIVRSNSPLHATHLPKTIMTSNLPHASNTRHPSSFSPSPIKTL 125
            T I LF++   F F+NRPI     P  A     + + S +P  ++T  P +  PSP ++ 
Sbjct: 1423 TIIELFIQQCPFFFYNRPI---TEPPGARPSSPSAVASTVPFLTST--PVTSQPSPPQSP 1477

Query: 126  LPHSHPFLRPLFTSLIAYQTPS 147
             P     ++PL  S +    P+
Sbjct: 1478 PPTPQSPMQPLLPSPLHPHRPT 1499


>NFC2_MOUSE (Q60591) Nuclear factor of activated T-cells,
           cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT
           pre-existing subunit) (NF-ATp)
          Length = 1064

 Score = 30.8 bits (68), Expect = 8.4
 Identities = 27/115 (23%), Positives = 46/115 (39%), Gaps = 3/115 (2%)

Query: 203 PNHSSSSSGSDPDATAAGGLRLEAPEIPPYRLKTYATLPLPVQIAPTHEAIDQPSIFQNS 262
           P   SSS G+    + A  L    P   P R ++ +  P P  +AP  ++I  P+ +  +
Sbjct: 243 PASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSP-HVAPQDDSI--PAGYPPT 299

Query: 263 DLIVQFVNSLGGLSNDDEFSAKLRIWICSPGDRPWLHKPDGDVKRSHFFFAYEYM 317
                 +++L  L+ D       +IW  SP   P    P       H +   E++
Sbjct: 300 AGSAVLMDALNTLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPTVEFL 354


>ATX2_MOUSE (O70305) Ataxin-2 (Spinocerebellar ataxia type 2 protein
            homolog)
          Length = 1285

 Score = 30.8 bits (68), Expect = 8.4
 Identities = 18/53 (33%), Positives = 27/53 (49%), Gaps = 1/53 (1%)

Query: 108  ASNTRHPSSFSPSPIKTLLPHSHPFLRPLFTS-LIAYQTPSAHFRSGAVAYHP 159
            ASNT+ P S  P+  +T+       ++P +T+       P AH +SG V  HP
Sbjct: 1181 ASNTQSPQSSFPAAQQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHP 1233


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.322    0.138    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,195,790
Number of Sequences: 164201
Number of extensions: 2799236
Number of successful extensions: 6163
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 6156
Number of HSP's gapped (non-prelim): 19
length of query: 494
length of database: 59,974,054
effective HSP length: 114
effective length of query: 380
effective length of database: 41,255,140
effective search space: 15676953200
effective search space used: 15676953200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)