BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0026.7
         (303 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

VAL1_TYLCU (P38609) AL1 protein (C1 protein)                           33  0.67
AXN1_MOUSE (O35625) Axin 1 (Axis inhibition protein 1) (Fused pr...    31  3.3
NU42_YEAST (P49686) Nucleoporin NUP42 (Nuclear pore protein NUP42)     31  4.3
ATRX_MOUSE (Q61687) Transcriptional regulator ATRX (X-linked nuc...    31  4.3
RGE2_MOUSE (Q8CHG7) Rap guanine nucleotide exchange factor 2 (PD...    30  7.4
MSN2_YEAST (P33748) Zinc finger protein MSN2 (Multicopy suppress...    30  7.4
AGRN_DISOM (Q90404) Agrin (Fragment)                                   30  7.4
VAL1_PYMVV (P27258) AL1 protein                                        30  9.6
MM12_MOUSE (P34960) Macrophage metalloelastase precursor (EC 3.4...    30  9.6
HEM2_RAT (P06214) Delta-aminolevulinic acid dehydratase (EC 4.2....    30  9.6
HEM2_MOUSE (P10518) Delta-aminolevulinic acid dehydratase (EC 4....    30  9.6
AXN1_RAT (O70239) Axin 1 protein (Axis inhibition protein 1) (rA...    30  9.6

>VAL1_TYLCU (P38609) AL1 protein (C1 protein)
          Length = 359

 Score = 33.5 bits (75), Expect = 0.67
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 5/79 (6%)

Query: 125 ETLLRLLLPLNDKVQWTSHNVASSEPPTLPQSEHFTGPFNRLRSRSLTELTTQIAPPNKN 184
           E LL+L  P N K       +     P L     F G FN   +R        +  P ++
Sbjct: 30  EQLLQLQTPTNKKYIKICRELHEDGQPHLHMLIQFEGKFNCKNNRFF-----DLVSPTRS 84

Query: 185 GHAPPHIESRKSSQSVNPY 203
            H  P+I+  KSS  V  Y
Sbjct: 85  AHFHPNIQGAKSSSDVKSY 103


>AXN1_MOUSE (O35625) Axin 1 (Axis inhibition protein 1) (Fused
           protein)
          Length = 863

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 13/125 (10%)

Query: 109 SSSMRDDNDSSAGSPTETLLRLLLP-LNDKVQWTSHNVASSEPPTLPQSEHFTGPFNRLR 167
           S S +  +D S+GS T   +   LP LN+  +W     A  +    P       P +RL 
Sbjct: 215 SESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPL------PPSRLT 268

Query: 168 SRSLTELTTQIAPPNKNGHAPPHIESRKSSQSVNPYYVWTCCSSFINPRISPLTMKYECP 227
            + L E     AP ++  +    +      + VNPYYV +         ++P T   +  
Sbjct: 269 QKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNS------GYALAPATSANDSE 322

Query: 228 QLSLS 232
           Q SLS
Sbjct: 323 QQSLS 327


>NU42_YEAST (P49686) Nucleoporin NUP42 (Nuclear pore protein NUP42)
          Length = 430

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 10/94 (10%)

Query: 104 RISLRSSSMRDDNDSSAGSPTETLLRLLLPLNDKVQWTSHNVASSE----PPTLPQSEHF 159
           + ++ SSS+ + N+S+ G+ + T L    P     Q  S N +S+      PT   + + 
Sbjct: 154 KTAIPSSSVSNSNNSAFGAASNTPLTTTSPFGSLQQNASQNASSTSSAFGKPTFGAATNT 213

Query: 160 TGPFNRLRSRSLTELTTQIAP-----PNKNGHAP 188
             PF  +++ S T   T ++P      N N  +P
Sbjct: 214 QSPFGTIQNTS-TSSGTGVSPFGTFGTNSNNKSP 246


>ATRX_MOUSE (Q61687) Transcriptional regulator ATRX (X-linked nuclear
            protein) (Heterochromatin protein 2) (HP1
            alpha-interacting protein) (HP1-BP38 protein)
          Length = 2476

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 31/136 (22%), Positives = 55/136 (39%), Gaps = 11/136 (8%)

Query: 48   RSATEDASLDYNSDALGDRFSWWALPGRRALNLMASGATCVQRLNGSRDSAIHTKYRISL 107
            R+  E  S   +SDA G          +R      +G T  ++ N  R +    +  I+ 
Sbjct: 1123 RNTKEVKSASSSSDAEGSSEDNKKQKKQRTSAKKKTGNTKEKKRNSLRATPKRKQVDITS 1182

Query: 108  RSSSMRDDNDSSAGSPTETLLRLLLPLNDKVQWTSHN----------VASSEPPTLPQSE 157
             SS + DD+ +SAG  +    + + P+ + +   SH           ++ S P T+   +
Sbjct: 1183 SSSDIGDDDQNSAGEESSDEQK-IKPVTENLVLPSHTGFCQSSGDEALSKSVPATVDDDD 1241

Query: 158  HFTGPFNRLRSRSLTE 173
                P NR+  + L E
Sbjct: 1242 DDNDPENRIAKKMLLE 1257


>RGE2_MOUSE (Q8CHG7) Rap guanine nucleotide exchange factor 2 (PDZ
           domain containing guanine nucleotide exchange factor 1)
           (PDZ-GEF1) (Fragment)
          Length = 1138

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 31/123 (25%), Positives = 45/123 (36%), Gaps = 12/123 (9%)

Query: 10  STQVSKHAETARAAIHNHGSGHNGALTLSGAPF--------QGTWARSATEDASLDYNSD 61
           ST+   H +  RA++    SG     + S            Q +W          DY+  
Sbjct: 866 STEELSHDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYS-- 923

Query: 62  ALGDRFSWWALPGRRALNLMASGATCVQRLNGSRDSAIHTKYRISLRSSSMRDDNDSSAG 121
             GD  S WA  G     + +  +T   R N SR+S    + R S  SS+     DS   
Sbjct: 924 --GDAASIWASGGHMDQMMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGD 981

Query: 122 SPT 124
           + T
Sbjct: 982 TGT 984


>MSN2_YEAST (P33748) Zinc finger protein MSN2 (Multicopy suppressor
           of SNF1 protein 2)
          Length = 704

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 115 DNDSSAGSPTETLLRLLLPLNDKVQWTSHNVASSEPPTLPQSEHFTGPFNRLRSRSLTEL 174
           +N S +G+   T L    P+ND +   ++ + S  P ++PQ+     P N   +      
Sbjct: 116 NNASGSGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTINPPINTASNE----- 170

Query: 175 TTQIAPPNKNGH 186
            T ++P   NG+
Sbjct: 171 -TNLSPQTSNGN 181


>AGRN_DISOM (Q90404) Agrin (Fragment)
          Length = 1328

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 40/164 (24%), Positives = 61/164 (36%), Gaps = 11/164 (6%)

Query: 140 WTSHNVASSEPPTLPQSEHFTGPFNRLRSRSLTELTTQIAPPNKNGHAPPHIESRKSSQS 199
           W   ++ SSEPP L  S  F+G  +   S +L     +    N++   PP     + S  
Sbjct: 327 WPPSSLTSSEPPDLSGSGDFSGDTDLEASGNLEGSGVEPMGFNESSTGPPTPVPNERSTC 386

Query: 200 VNPYYVWTCCSSFINPRISPLTMKYECPQLSLSIITPMPKAKTIGKERI-ASKRDEPTGE 258
            N  +   CCS    P +        CP   L     +   +  G+E     + D+P  E
Sbjct: 387 DNTEF--GCCSDGKTPSVD--GEGSNCPPTKL-FQGVLIVEEVEGQELFYTPEMDDPKSE 441

Query: 259 HQRQTDRPNPRSNYELFNCNNLNIRYWSWNYRGCWHQTCSPMDP 302
              +T R    +  ELF  +N+   + S    G       P DP
Sbjct: 442 LFGETARSIENALNELFGNSNVKKDFKSVRVHG-----LGPSDP 480


>VAL1_PYMVV (P27258) AL1 protein
          Length = 361

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 20/77 (25%), Positives = 31/77 (39%), Gaps = 5/77 (6%)

Query: 127 LLRLLLPLNDKVQWTSHNVASSEPPTLPQSEHFTGPFNRLRSRSLTELTTQIAPPNKNGH 186
           L  L +P+N K       +  +  P L     F G +N   +R        +  P ++ H
Sbjct: 32  LQNLTIPVNKKFIKICRELHENGEPHLHVLIQFEGKYNCTNNRLF-----DLVSPTRSTH 86

Query: 187 APPHIESRKSSQSVNPY 203
             P+I+  KSS  V  Y
Sbjct: 87  FHPNIQGAKSSSDVKSY 103


>MM12_MOUSE (P34960) Macrophage metalloelastase precursor (EC
           3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12)
          Length = 462

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 17/45 (37%), Positives = 21/45 (45%), Gaps = 5/45 (11%)

Query: 65  DRFSWWALPGRRALNLMASGATCVQRLNGSRDSAIHTKYRISLRS 109
           D F WW LPG  A N+     T +  +  S  SAI   Y I  R+
Sbjct: 296 DWFFWWKLPGSPATNI-----TSISSIWPSIPSAIQAAYEIESRN 335


>HEM2_RAT (P06214) Delta-aminolevulinic acid dehydratase (EC
           4.2.1.24) (Porphobilinogen synthase) (ALADH)
          Length = 330

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 23/78 (29%), Positives = 33/78 (41%), Gaps = 3/78 (3%)

Query: 5   QADARSTQVSKHAETARAAIHNHGSGHNGALTLSGAPFQGTWARSATEDASLDYNSDALG 64
           Q  A S  +    E  +AA+  HG G+  ++    A F   +     + A    +S A G
Sbjct: 163 QVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAKFASCFYGPFRDAAQ---SSPAFG 219

Query: 65  DRFSWWALPGRRALNLMA 82
           DR  +   PG R L L A
Sbjct: 220 DRRCYQLPPGARGLALRA 237


>HEM2_MOUSE (P10518) Delta-aminolevulinic acid dehydratase (EC
           4.2.1.24) (Porphobilinogen synthase) (ALADH)
          Length = 330

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 23/78 (29%), Positives = 33/78 (41%), Gaps = 3/78 (3%)

Query: 5   QADARSTQVSKHAETARAAIHNHGSGHNGALTLSGAPFQGTWARSATEDASLDYNSDALG 64
           Q  A S  +    E  +AA+  HG G+  ++    A F   +     + A    +S A G
Sbjct: 163 QVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAKFASCFYGPFRDAAQ---SSPAFG 219

Query: 65  DRFSWWALPGRRALNLMA 82
           DR  +   PG R L L A
Sbjct: 220 DRRCYQLPPGARGLALRA 237


>AXN1_RAT (O70239) Axin 1 protein (Axis inhibition protein 1)
           (rAxin)
          Length = 827

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 13/125 (10%)

Query: 109 SSSMRDDNDSSAGSPTETLLRLLLP-LNDKVQWTSHNVASSEPPTLPQSEHFTGPFNRLR 167
           S S +  +D S+GS T   +   LP LN+  +W     A  +          + P +RL 
Sbjct: 215 SESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADED------DGRDSVPPSRLT 268

Query: 168 SRSLTELTTQIAPPNKNGHAPPHIESRKSSQSVNPYYVWTCCSSFINPRISPLTMKYECP 227
            + L E     AP ++  +    +      + VNPYYV +         ++P T   +  
Sbjct: 269 QKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNS------GYALAPATSANDSE 322

Query: 228 QLSLS 232
           Q SLS
Sbjct: 323 QQSLS 327


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.314    0.128    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,167,946
Number of Sequences: 164201
Number of extensions: 1517798
Number of successful extensions: 3531
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3529
Number of HSP's gapped (non-prelim): 13
length of query: 303
length of database: 59,974,054
effective HSP length: 110
effective length of query: 193
effective length of database: 41,911,944
effective search space: 8089005192
effective search space used: 8089005192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)