Lotus
BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= TM0018.1
         (127 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

RBM8_MOUSE (Q9CWZ3) RNA-binding protein 8A (RNA binding motif pr...    51  5e-07
RBM8_HUMAN (Q9Y5S9) RNA-binding protein 8A (RNA binding motif pr...    51  5e-07
RBM8_DROME (Q9V535) RNA-binding protein 8A (Tsunagi protein)           49  2e-06
PPIE_DROME (Q9V3G3) Peptidyl-prolyl cis-trans isomerase E (EC 5....    38  0.003
PUB1_YEAST (P32588) Nuclear and cytoplasmic polyadenylated RNA-b...    37  0.010
PPIE_MOUSE (Q9QZH3) Peptidyl-prolyl cis-trans isomerase E (EC 5....    36  0.013
PPIE_HUMAN (Q9UNP9) Peptidyl-prolyl cis-trans isomerase E (EC 5....    36  0.013
PAB2_ARATH (P42731) Polyadenylate-binding protein 2 (Poly(A)-bin...    36  0.017
PAB1_RAT (Q9EPH8) Polyadenylate-binding protein 1 (Poly(A)-bindi...    36  0.017
PAB1_MOUSE (P29341) Polyadenylate-binding protein 1 (Poly(A)-bin...    36  0.017
PAB1_HUMAN (P11940) Polyadenylate-binding protein 1 (Poly(A)-bin...    36  0.017
PAB1_BOVIN (P61286) Polyadenylate-binding protein 1 (Poly(A)-bin...    36  0.017
PPIE_SCHMA (Q26548) Peptidyl-prolyl cis-trans isomerase E (EC 5....    35  0.022
NUCL_XENLA (P20397) Nucleolin (Protein C23)                            35  0.022
PAB3_HUMAN (Q9H361) Polyadenylate-binding protein 3 (Poly(A)-bin...    35  0.038
TR2A_MOUSE (Q6PFR5) Transformer-2 protein homolog (TRA-2 alpha)        34  0.065
TR2A_HUMAN (Q13595) Transformer-2 protein homolog (TRA-2 alpha)        34  0.065
RX21_DROME (Q24491) RNA binding protein Rsf1 (RNA binding protei...    34  0.065
PAB4_HUMAN (Q13310) Polyadenylate-binding protein 4 (Poly(A)-bin...    34  0.065
TR2B_RAT (P62997) Arginine/serine-rich splicing factor 10 (Trans...    33  0.085

>RBM8_MOUSE (Q9CWZ3) RNA-binding protein 8A (RNA binding motif
           protein 8A) (Ribonucleoprotein RBM8A)
          Length = 174

 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 2/55 (3%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIR--RKNARHP 53
           GY L+EYE  +EA+ A+E LNG +L+ Q I VDW F  GP     R  R+ +R P
Sbjct: 115 GYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSP 169


>RBM8_HUMAN (Q9Y5S9) RNA-binding protein 8A (RNA binding motif
           protein 8A) (Ribonucleoprotein RBM8A) (RNA-binding
           protein Y14) (Binder of OVCA1-1) (BOV-1)
          Length = 174

 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 2/55 (3%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIR--RKNARHP 53
           GY L+EYE  +EA+ A+E LNG +L+ Q I VDW F  GP     R  R+ +R P
Sbjct: 115 GYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSP 169


>RBM8_DROME (Q9V535) RNA-binding protein 8A (Tsunagi protein)
          Length = 165

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 24/50 (48%), Positives = 34/50 (68%), Gaps = 2/50 (4%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGP--INESIRRK 48
           GYAL+EYE  ++A  A E LNG+E++ Q I VDW F  GP  + +S +R+
Sbjct: 115 GYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEKRR 164


>PPIE_DROME (Q9V3G3) Peptidyl-prolyl cis-trans isomerase E (EC
          5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E)
          (Cyclophilin 33)
          Length = 300

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 18/35 (51%), Positives = 26/35 (73%)

Query: 1  GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWA 35
          G+A IEYE++E+A  AI+N+N SEL  + I V+ A
Sbjct: 48 GFAFIEYEQSEDAAAAIDNMNDSELCGRTIRVNLA 82


>PUB1_YEAST (P32588) Nuclear and cytoplasmic polyadenylated
           RNA-binding protein PUB1 (ARS consensus binding protein
           ACBP-60) (Poly(U)-binding protein) (Poly
           uridylate-binding protein)
          Length = 452

 Score = 36.6 bits (83), Expect = 0.010
 Identities = 13/37 (35%), Positives = 24/37 (64%)

Query: 2   YALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSS 38
           YA +EY ++ +A  A++ LNG ++    + ++WAF S
Sbjct: 116 YAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQS 152



 Score = 30.0 bits (66), Expect = 0.94
 Identities = 9/35 (25%), Positives = 23/35 (65%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWA 35
           GY  + +   ++A+NA++++ G +L  + + ++WA
Sbjct: 203 GYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWA 237


>PPIE_MOUSE (Q9QZH3) Peptidyl-prolyl cis-trans isomerase E (EC
          5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E)
          (Cyclophilin 33)
          Length = 301

 Score = 36.2 bits (82), Expect = 0.013
 Identities = 17/35 (48%), Positives = 25/35 (70%)

Query: 1  GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWA 35
          G+A +E+E AE+A  AI+N+N SEL  + I V+ A
Sbjct: 48 GFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLA 82


>PPIE_HUMAN (Q9UNP9) Peptidyl-prolyl cis-trans isomerase E (EC
          5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E)
          (Cyclophilin 33)
          Length = 301

 Score = 36.2 bits (82), Expect = 0.013
 Identities = 17/35 (48%), Positives = 25/35 (70%)

Query: 1  GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWA 35
          G+A +E+E AE+A  AI+N+N SEL  + I V+ A
Sbjct: 48 GFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLA 82


>PAB2_ARATH (P42731) Polyadenylate-binding protein 2
           (Poly(A)-binding protein 2) (PABP 2)
          Length = 629

 Score = 35.8 bits (81), Expect = 0.017
 Identities = 20/62 (32%), Positives = 28/62 (44%), Gaps = 6/62 (9%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRKNARHPVMNLNIY 60
           GY  ++Y   E A+ AIE LNG  L  + +YV      GP      R +  +     N+Y
Sbjct: 165 GYGFVQYANEESAQKAIEKLNGMLLNDKQVYV------GPFLRRQERDSTANKTKFTNVY 218

Query: 61  FK 62
            K
Sbjct: 219 VK 220



 Score = 30.4 bits (67), Expect = 0.72
 Identities = 18/68 (26%), Positives = 30/68 (43%), Gaps = 6/68 (8%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIR------RKNARHPV 54
           G+  + +E A++A  A+E+LNG +   +  YV  A         +R       K A    
Sbjct: 256 GFGFVNFENADDAARAVESLNGHKFDDKEWYVGRAQKKSERETELRVRYEQNLKEAADKF 315

Query: 55  MNLNIYFK 62
            + N+Y K
Sbjct: 316 QSSNLYVK 323


>PAB1_RAT (Q9EPH8) Polyadenylate-binding protein 1 (Poly(A)-binding
           protein 1) (PABP 1)
          Length = 636

 Score = 35.8 bits (81), Expect = 0.017
 Identities = 16/48 (33%), Positives = 27/48 (55%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRK 48
           G+  + +ER E+A+ A++ +NG EL  + IYV  A         ++RK
Sbjct: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRK 279



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 12/32 (37%), Positives = 19/32 (58%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GY  + +E  E A+ AIE +NG  L  + ++V
Sbjct: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170


>PAB1_MOUSE (P29341) Polyadenylate-binding protein 1
           (Poly(A)-binding protein 1) (PABP 1)
          Length = 636

 Score = 35.8 bits (81), Expect = 0.017
 Identities = 16/48 (33%), Positives = 27/48 (55%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRK 48
           G+  + +ER E+A+ A++ +NG EL  + IYV  A         ++RK
Sbjct: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRK 279



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 12/32 (37%), Positives = 19/32 (58%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GY  + +E  E A+ AIE +NG  L  + ++V
Sbjct: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170


>PAB1_HUMAN (P11940) Polyadenylate-binding protein 1
           (Poly(A)-binding protein 1) (PABP 1)
          Length = 636

 Score = 35.8 bits (81), Expect = 0.017
 Identities = 16/48 (33%), Positives = 27/48 (55%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRK 48
           G+  + +ER E+A+ A++ +NG EL  + IYV  A         ++RK
Sbjct: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRK 279



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 12/32 (37%), Positives = 19/32 (58%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GY  + +E  E A+ AIE +NG  L  + ++V
Sbjct: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170


>PAB1_BOVIN (P61286) Polyadenylate-binding protein 1
           (Poly(A)-binding protein 1) (PABP 1)
          Length = 636

 Score = 35.8 bits (81), Expect = 0.017
 Identities = 16/48 (33%), Positives = 27/48 (55%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRK 48
           G+  + +ER E+A+ A++ +NG EL  + IYV  A         ++RK
Sbjct: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRK 279



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 12/32 (37%), Positives = 19/32 (58%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GY  + +E  E A+ AIE +NG  L  + ++V
Sbjct: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170


>PPIE_SCHMA (Q26548) Peptidyl-prolyl cis-trans isomerase E (EC
          5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E)
          Length = 273

 Score = 35.4 bits (80), Expect = 0.022
 Identities = 15/35 (42%), Positives = 25/35 (70%)

Query: 1  GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWA 35
          G+A +E+E  E+A +AI+N+N SE+  + I V+ A
Sbjct: 12 GFAFVEFEEVEDAMSAIDNMNESEIFGRTIRVNVA 46


>NUCL_XENLA (P20397) Nucleolin (Protein C23)
          Length = 650

 Score = 35.4 bits (80), Expect = 0.022
 Identities = 14/40 (35%), Positives = 29/40 (72%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGP 40
           G+A IE+  AE+AK+A+++ N +E+  ++I ++++   GP
Sbjct: 451 GFAFIEFSSAEDAKDAMDSCNNTEIEGRSIRLEFSQGGGP 490



 Score = 30.4 bits (67), Expect = 0.72
 Identities = 12/34 (35%), Positives = 22/34 (64%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDW 34
           G A +E+   +EA  A+E   G+E+  ++I+VD+
Sbjct: 362 GIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDF 395


>PAB3_HUMAN (Q9H361) Polyadenylate-binding protein 3
           (Poly(A)-binding protein 3) (PABP 3) (Testis-specific
           poly(A)-binding protein)
          Length = 631

 Score = 34.7 bits (78), Expect = 0.038
 Identities = 13/32 (40%), Positives = 22/32 (68%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           G+  + +ER E+A+ A++ +NG EL  + IYV
Sbjct: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263



 Score = 27.3 bits (59), Expect = 6.1
 Identities = 11/32 (34%), Positives = 19/32 (59%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GY  + +E  E A+ AI+ +NG  L  + ++V
Sbjct: 139 GYGFVHFETHEAAERAIKKMNGMLLNGRKVFV 170


>TR2A_MOUSE (Q6PFR5) Transformer-2 protein homolog (TRA-2 alpha)
          Length = 281

 Score = 33.9 bits (76), Expect = 0.065
 Identities = 14/37 (37%), Positives = 25/37 (66%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFS 37
           G+A + +ER +++K A+E  NG EL  + I VD++ +
Sbjct: 159 GFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSIT 195


>TR2A_HUMAN (Q13595) Transformer-2 protein homolog (TRA-2 alpha)
          Length = 282

 Score = 33.9 bits (76), Expect = 0.065
 Identities = 14/37 (37%), Positives = 25/37 (66%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFS 37
           G+A + +ER +++K A+E  NG EL  + I VD++ +
Sbjct: 161 GFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSIT 197


>RX21_DROME (Q24491) RNA binding protein Rsf1 (RNA binding protein
          Rox21)
          Length = 197

 Score = 33.9 bits (76), Expect = 0.065
 Identities = 14/33 (42%), Positives = 23/33 (69%)

Query: 1  GYALIEYERAEEAKNAIENLNGSELLTQNIYVD 33
          G+A +E+E  ++A+ A + LNGSELL   + V+
Sbjct: 44 GFAFVEFEHRDDAEKACDILNGSELLGSQLRVE 76


>PAB4_HUMAN (Q13310) Polyadenylate-binding protein 4
           (Poly(A)-binding protein 4) (PABP 4) (Inducible
           poly(A)-binding protein) (iPABP) (Activated-platelet
           protein-1) (APP-1)
          Length = 644

 Score = 33.9 bits (76), Expect = 0.065
 Identities = 15/48 (31%), Positives = 26/48 (53%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGPINESIRRK 48
           G+  + YE+ E+A  A+E +NG E+  + I+V  A         ++RK
Sbjct: 232 GFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRK 279



 Score = 30.4 bits (67), Expect = 0.72
 Identities = 13/32 (40%), Positives = 19/32 (58%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYV 32
           GYA + +E  E A  AIE +NG  L  + ++V
Sbjct: 139 GYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170


>TR2B_RAT (P62997) Arginine/serine-rich splicing factor 10
           (Transformer-2-beta) (HTRA2-beta) (Transformer 2 protein
           homolog) (RA301)
          Length = 288

 Score = 33.5 bits (75), Expect = 0.085
 Identities = 15/40 (37%), Positives = 24/40 (59%)

Query: 1   GYALIEYERAEEAKNAIENLNGSELLTQNIYVDWAFSSGP 40
           G+A + +E  ++AK A E  NG EL  + I VD++ +  P
Sbjct: 160 GFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRP 199


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.323    0.141    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,176,812
Number of Sequences: 164201
Number of extensions: 582617
Number of successful extensions: 1577
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1365
Number of HSP's gapped (non-prelim): 224
length of query: 127
length of database: 59,974,054
effective HSP length: 103
effective length of query: 24
effective length of database: 43,061,351
effective search space: 1033472424
effective search space used: 1033472424
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)


Lotus: description of TM0018.1