BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0017.9
(387 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RA50_ARCFU (O29230) DNA double-strand break repair rad50 ATPase 48 4e-05
CENE_HUMAN (Q02224) Centromeric protein E (CENP-E protein) 48 4e-05
RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase 47 6e-05
SMC4_MOUSE (Q8CG47) Structural maintenance of chromosomes 4-like... 47 8e-05
RA50_AQUAE (O67124) Probable DNA double-strand break repair rad5... 47 8e-05
SMC4_MICAR (Q9ERA5) Structural maintenance of chromosomes 4-like... 47 1e-04
RA50_SULAC (O33600) DNA double-strand break repair rad50 ATPase 47 1e-04
SMC4_HUMAN (Q9NTJ3) Structural maintenance of chromosomes 4-like... 46 1e-04
RA50_PYRHO (O58687) DNA double-strand break repair rad50 ATPase 46 1e-04
EEA1_MOUSE (Q8BL66) Early endosome antigen 1 (Fragment) 45 2e-04
TPM2_YEAST (P40414) Tropomyosin 2 45 4e-04
SCP1_HUMAN (Q15431) Synaptonemal complex protein 1 (SCP-1 protein) 45 4e-04
RA50_METJA (Q58718) DNA double-strand break repair rad50 ATPase 45 4e-04
KTN1_HUMAN (Q86UP2) Kinectin (Kinesin receptor) (CG-1 antigen) 45 4e-04
USO1_YEAST (P25386) Intracellular protein transport protein USO1 44 5e-04
KTN1_VULVU (O97961) Kinectin 44 7e-04
MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper prote... 44 0.001
MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B) 44 0.001
MYS2_DICDI (P08799) Myosin II heavy chain, non muscle 44 0.001
MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (S... 44 0.001
>RA50_ARCFU (O29230) DNA double-strand break repair rad50 ATPase
Length = 886
Score = 48.1 bits (113), Expect = 4e-05
Identities = 38/139 (27%), Positives = 78/139 (55%), Gaps = 20/139 (14%)
Query: 249 FVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
F+ QE Q K++I + +K +ES LR L E N+E ++ +E++
Sbjct: 178 FLSQEEQIKRQKEEKKAEIERISEEIKSIES-------LREKLSEEVRNLE--SRLKELE 228
Query: 309 AAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSML 368
K+ +ESLR+Q S ++ + E+++ +++K++ E+ +R+++LE K+ E+++ L
Sbjct: 229 EHKSR----LESLRKQESSVLQEVRGLEEKLRELEKQLKEVVERIEDLEKKAKEVKE--L 282
Query: 369 SSKSEVENLHRKSLIDELL 387
K+E R S++++LL
Sbjct: 283 KPKAE-----RYSILEKLL 296
Score = 40.4 bits (93), Expect = 0.008
Identities = 36/152 (23%), Positives = 76/152 (49%), Gaps = 22/152 (14%)
Query: 251 VQELQSDSIMHLTKSK--INELVAILKDVESAQLRVAWLRSALDEIAENV-EVINQHQEV 307
V++ + DSI+ +S+ I + ++D E+A + + L+ E + E ++Q +++
Sbjct: 126 VRQGEIDSIIRDDESRERIIRQITRIEDYENAWKNLGAVIRMLEREKERLKEFLSQEEQI 185
Query: 308 DAAKANTDREMESLREQLESEMESLAEK-EQEVADIKKRIPEISD--------------- 351
K E+E + E+++S +ESL EK +EV +++ R+ E+ +
Sbjct: 186 KRQKEEKKAEIERISEEIKS-IESLREKLSEEVRNLESRLKELEEHKSRLESLRKQESSV 244
Query: 352 --RLKELELKSAELEQSMLSSKSEVENLHRKS 381
++ LE K ELE+ + +E+L +K+
Sbjct: 245 LQEVRGLEEKLRELEKQLKEVVERIEDLEKKA 276
Score = 39.7 bits (91), Expect = 0.013
Identities = 31/128 (24%), Positives = 59/128 (45%), Gaps = 11/128 (8%)
Query: 264 KSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLRE 323
K+ + E +K + + + L E E VE + QE E+++L
Sbjct: 450 KNIMAEYTREMKRIAEELAKADEIEKKLKERLEKVEKALEKQETVLKYRQMVDELKALEN 509
Query: 324 QLES-EMESLAEKEQEVADIKKRIPEI----------SDRLKELELKSAELEQSMLSSKS 372
+L S + E L+ + +E +K+R+ + + R+KEL+ E+E+++ + +S
Sbjct: 510 ELSSHDAEKLSAESEEYRKVKERLDGLRGQQKILLSSASRIKELKSSLREIEEALKNVES 569
Query: 373 EVENLHRK 380
E LHRK
Sbjct: 570 ERGELHRK 577
Score = 34.7 bits (78), Expect = 0.42
Identities = 22/120 (18%), Positives = 60/120 (49%), Gaps = 1/120 (0%)
Query: 239 LRSYYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENV 298
LR +Y + + E + +S + + +E+ + +E A + +R +DE+ +
Sbjct: 596 LRPFYNKWLELKDAESRLESELKRREKLEDEISEAIAKLEEANGKAEEIRGQIDELLR-I 654
Query: 299 EVINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELEL 358
+H+ + +E+ L+ +LE+ ESL E+++ +++++ ++ + K++E+
Sbjct: 655 YSEEEHRRLSDEHLRKSKELAGLKSRLETLRESLQSAEKDLKFLEEQLAKMDEYRKKVEV 714
>CENE_HUMAN (Q02224) Centromeric protein E (CENP-E protein)
Length = 2663
Score = 48.1 bits (113), Expect = 4e-05
Identities = 37/144 (25%), Positives = 73/144 (50%), Gaps = 13/144 (9%)
Query: 257 DSIMHLTKSKINELVAILKDVESAQ-------LRVAW-LRSALDEIAENVEVINQHQEVD 308
D + + K NE+ + KD+E + L++ LR A + E E I++ + +
Sbjct: 1738 DKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV 1797
Query: 309 AAK----ANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELE-LKSAEL 363
+ K +N +++E+ +L+ +++ L E ++ +KK + E ++ E+E LK
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIK 1857
Query: 364 EQSMLSSKSEVENLHRKSLIDELL 387
+QS+ SK E+ENL+ + E L
Sbjct: 1858 DQSLTLSKLEIENLNLAQELHENL 1881
Score = 41.6 bits (96), Expect = 0.003
Identities = 27/110 (24%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
Query: 268 NELVAILKDVESAQLRVAWLRSALDEIAENV-EVINQHQEVDAAKANTDREMESLREQLE 326
+E+ ++ K+ + Q L+S D++ EN+ E++ +H E + ++ E +
Sbjct: 1435 DEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETIN 1494
Query: 327 SEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM-LSSKSEVE 375
+L+EKE E++ I+K++ I+D+L+ + E E+ + + SEV+
Sbjct: 1495 ELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQ 1544
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/135 (25%), Positives = 66/135 (47%), Gaps = 28/135 (20%)
Query: 255 QSDSIMHLTKSKINELVAILKDV--ESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKA 312
Q I L + K NEL +L+ V E QL+ ++ EN+E+ ++QE
Sbjct: 1041 QQRKIFSLIQEK-NELQQMLESVIAEKEQLKT--------DLKENIEMTIENQE------ 1085
Query: 313 NTDREMESLREQLESEMESLAE-------KEQEVADIKKRIPEISDRLKELELKSAELEQ 365
E+ L ++L+ + E +A+ KE E++ R+ E+ ++LKE + E +Q
Sbjct: 1086 ----ELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQ 1141
Query: 366 SMLSSKSEVENLHRK 380
+L+ + E+ + +K
Sbjct: 1142 QLLNVQEEMSEMQKK 1156
Score = 38.1 bits (87), Expect = 0.038
Identities = 56/295 (18%), Positives = 112/295 (36%), Gaps = 45/295 (15%)
Query: 131 EEDQQKNGVEHLANPIQTKQEDKTASDVHPGEGLATTFKGGSIDFSFSGIIPQGNEDNDD 190
E DQ K + KQE+ +H E T K I + I +D +
Sbjct: 1701 ERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760
Query: 191 KGDT---ESVVSESRVPVGKYHVKES------FASILESILDKYGDIGASCHLESLVLRS 241
D + + + + + H+KE I+ DK ++ + L+
Sbjct: 1761 SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820
Query: 242 YYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLR----SALDEIAEN 297
E Q + ++ T+ K++E+ + K ++ L ++ L + E+ EN
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHEN 1880
Query: 298 VEVI--------NQHQEVDAAKANTDREMESLRE------QLESEM-------------- 329
+E + N + + K D+ ESL+E +++ E+
Sbjct: 1881 LEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETV 1940
Query: 330 ----ESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
E ++EK +++DI+K + + D L++ + + E +L K +V H+K
Sbjct: 1941 DKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK 1995
Score = 35.0 bits (79), Expect = 0.32
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 16/115 (13%)
Query: 287 LRSALDEIAENVEVINQHQEVDAAK-----------ANTDREMESLREQLESEMESLAEK 335
LR DE+ + E++ Q + K A + +++ +QL+ + + L
Sbjct: 1087 LRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNV 1146
Query: 336 EQEVADIKKRIPEISD-----RLKELELKSAELEQSMLSSKSEVENLHRKSLIDE 385
++E+++++K+I EI + + KEL L+ E E+ L+ K KS+ E
Sbjct: 1147 QEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKE 1201
Score = 33.1 bits (74), Expect = 1.2
Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 38/155 (24%)
Query: 251 VQELQSDSI--------MHLTKSKINELVAILKDVE-----SAQLRVAWLRSALDEIAEN 297
+QELQ + ++++ KINE+ + K E ++ L L E E
Sbjct: 1972 IQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESLEE 2031
Query: 298 VEVINQHQEV-----DAAKANTDREMESLREQLESE--------------------MESL 332
+ ++ + ++ ++ K D+ + +LRE + + MESL
Sbjct: 2032 IRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMESL 2091
Query: 333 AEKEQEVADIKKRIPEISDRLKELELKSAELEQSM 367
EK + ++ KR E+ D + L S +LE+ +
Sbjct: 2092 REKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEI 2126
Score = 33.1 bits (74), Expect = 1.2
Identities = 40/209 (19%), Positives = 87/209 (41%), Gaps = 19/209 (9%)
Query: 190 DKGDTESVVSESRVPVGKYHVKESFASILESIL------DKYGDIGASCHLESLVLRSYY 243
++ T+ + +R+ + + + E F E I D I + ++ L+ +
Sbjct: 1313 EQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHI 1372
Query: 244 IECVCFVVQELQSDSIMHLT-KSKINELVAILKDVESAQLR-VAWLRSALDEIAENVEVI 301
E + +QE QS L K K NE I+ ++E + + A LR ++ + + +
Sbjct: 1373 RETLA-KIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ 1431
Query: 302 NQHQEVDAAKANTD----------REMESLREQLESEMESLAEKEQEVADIKKRIPEISD 351
H E+ + D E + L+E ++ + E E+E+ + E +
Sbjct: 1432 ESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEE 1491
Query: 352 RLKELELKSAELEQSMLSSKSEVENLHRK 380
+ EL + +E E + + + ++E ++ K
Sbjct: 1492 TINELRVNLSEKETEISTIQKQLEAINDK 1520
Score = 32.3 bits (72), Expect = 2.1
Identities = 29/144 (20%), Positives = 70/144 (48%), Gaps = 16/144 (11%)
Query: 250 VVQELQSDSIMHLTKSKINELVAILKDVESA------QLRVAWLRSALDEIAENVEVINQ 303
V++ELQ +++ + L ++++E+ +L++A + L E E ++ + +
Sbjct: 1204 VLKELQKSF-----ETERDHLRGYIREIEATGLQTKEELKIAHIH--LKEHQETIDELRR 1256
Query: 304 HQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELEL--KSA 361
A+ +++E +L+ E+ L E+++ + ++KK + E + + ELEL + +
Sbjct: 1257 SVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKK-VSETQETMNELELLTEQS 1315
Query: 362 ELEQSMLSSKSEVENLHRKSLIDE 385
+ S ++ E+E L E
Sbjct: 1316 TTKDSTTLARIEMERLRLNEKFQE 1339
Score = 32.3 bits (72), Expect = 2.1
Identities = 24/136 (17%), Positives = 69/136 (50%), Gaps = 9/136 (6%)
Query: 253 ELQSDSIMH-LTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAK 311
+L+ D + L ++K +L I +++++A++ + +D++ E + E
Sbjct: 1902 KLERDQLKESLQETKARDL-EIQQELKTARMLSKEHKETVDKLREKIS------EKTIQI 1954
Query: 312 ANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSK 371
++ ++++ +++L+ +++ L +KE ++ +K+ + ++ E+E + E + L K
Sbjct: 1955 SDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEPNYL-CK 2013
Query: 372 SEVENLHRKSLIDELL 387
E++N + E L
Sbjct: 2014 CEMDNFQLTKKLHESL 2029
Score = 32.0 bits (71), Expect = 2.7
Identities = 19/61 (31%), Positives = 33/61 (53%)
Query: 317 EMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVEN 376
EME L+EQLE+ L E+E I +++ + + +K L + +L+Q S + E +
Sbjct: 888 EMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947
Query: 377 L 377
L
Sbjct: 948 L 948
>RA50_SULSO (Q97WH0) DNA double-strand break repair rad50 ATPase
Length = 864
Score = 47.4 bits (111), Expect = 6e-05
Identities = 40/151 (26%), Positives = 77/151 (50%), Gaps = 15/151 (9%)
Query: 245 ECVCFVVQ-ELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAE-NVEVIN 302
E +++Q EL + + K NEL I ++ A + + ++ + N E+ N
Sbjct: 444 EAKSYILQLELNKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLNEEIEN 503
Query: 303 QHQEVDAAKANTDREMESLREQLES------EMESLAEKEQEVADIKKRIPEISDRLKEL 356
H E+++ K N D E++ + E+++ E L++ +E D KKR+ +L E+
Sbjct: 504 LHSEIESLK-NIDEEIKKINEEVKELKLYYEEFMRLSKYTKEELD-KKRV-----KLDEM 556
Query: 357 ELKSAELEQSMLSSKSEVENLHRKSLIDELL 387
+ K E+E+ M +SE++ L RK+L ++L
Sbjct: 557 KKKKEEIEKEMRGLESELKGLDRKALESKIL 587
Score = 32.0 bits (71), Expect = 2.7
Identities = 25/102 (24%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 266 KINELVAILKDVESAQLRVA-WLRSALDEIAENV-EVINQHQEVDAAKANTDREMESL-R 322
KINE V LK +R++ + + LD+ + E+ + +E++ + E++ L R
Sbjct: 520 KINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDEMKKKKEEIEKEMRGLESELKGLDR 579
Query: 323 EQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELE 364
+ LES++ L K ++ ++KK+ + D +++++L E++
Sbjct: 580 KALESKILDLENKRVKLDEMKKKKGILEDYIRQVKLLQEEVK 621
Score = 32.0 bits (71), Expect = 2.7
Identities = 33/176 (18%), Positives = 76/176 (42%), Gaps = 36/176 (20%)
Query: 189 DDKGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVC 248
D + TE + ++ P+ + A+++ + ++K I L ++++R ++ +
Sbjct: 85 DIRSTTEDRLIRNQFPIARS------ATVVSNEIEKILGIDKDIALSTIIVRQGELDKIL 138
Query: 249 FVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
QE+ KI +L I K ++S R + E +N+E
Sbjct: 139 ENFQEIMG---------KILKLELIEKLIDS--------RGPIVEFRKNLE--------- 172
Query: 309 AAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELE 364
N RE++ + + + +++ EK V ++KK ++ D +K LE + +++
Sbjct: 173 ----NKLRELDRIEQDYNNFKKTVEEKRARVLELKKDKEKLEDEIKNLEKRIKDIK 224
Score = 30.8 bits (68), Expect = 6.1
Identities = 29/127 (22%), Positives = 51/127 (39%), Gaps = 14/127 (11%)
Query: 266 KINELVAILKDVESAQLRV-AWLRSALDEIAENVEVINQHQEVDAA-------------K 311
K+N L +++ QL + A L I+E E+IN +V+ K
Sbjct: 379 KVNSLEQKVEETRKKQLNLRAQLAKVESLISEKNEIINNISQVEGETCPVCGRPLDEEHK 438
Query: 312 ANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSK 371
+E +S QLE L E+ +++ + +I RL + + + +
Sbjct: 439 QKIIKEAKSYILQLELNKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLN 498
Query: 372 SEVENLH 378
E+ENLH
Sbjct: 499 EEIENLH 505
>SMC4_MOUSE (Q8CG47) Structural maintenance of chromosomes 4-like 1
protein (Chromosome-associated polypeptide C) (XCAP-C
homolog)
Length = 1286
Score = 47.0 bits (110), Expect = 8e-05
Identities = 29/130 (22%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAK 311
+E + + + S E + K+ E + + +++E +EV ++ ++
Sbjct: 451 REKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSR 510
Query: 312 ANTD-REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
NT ++ +E L + E+L E++ + DI ++P+ LKE E + +L Q ++
Sbjct: 511 HNTAVSQLSKAKEALITASETLKERKAAIKDINTKLPQTQQELKEKEKELQKLTQEEINL 570
Query: 371 KSEVENLHRK 380
KS V +L +K
Sbjct: 571 KSLVHDLFQK 580
Score = 32.7 bits (73), Expect = 1.6
Identities = 23/115 (20%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 264 KSKINELVAILKDVESAQLRVAWLRSALDEIAENV-EVINQHQEVDAAKANTDREMESLR 322
+++I L + D+ + +L+ ++ LD I + + E + + A DR ++ +
Sbjct: 879 EAEIKRLHNTIIDINNRKLKAQ--QNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQ 936
Query: 323 EQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENL 377
+ + + + + E+E+ D+K + I D+ +E+ + E S+ + E NL
Sbjct: 937 DSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNL 991
>RA50_AQUAE (O67124) Probable DNA double-strand break repair rad50
ATPase
Length = 978
Score = 47.0 bits (110), Expect = 8e-05
Identities = 40/141 (28%), Positives = 68/141 (47%), Gaps = 25/141 (17%)
Query: 260 MHLTKSKINELVAILKDV-------------ESAQLRVAWLRSALDEIAENVEVINQH-Q 305
+ L K KI E ++K+ ES + + ++ S L EI E + + +H +
Sbjct: 608 LELLKEKIREKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQEIEEKEKKLRKHFE 667
Query: 306 EVDAAKANTDREMESLREQLESEMESLAEKEQEVADI------KKRIPEI--SDRLKELE 357
E+ + K+ + E+ +L E + S E EK +E+A+I + + E+ D+ ELE
Sbjct: 668 ELSSRKSKLEGELSALNESINSLEEERKEKLKELANIYEVAKSPREVVELYLGDKEAELE 727
Query: 358 LKSAELEQSMLS---SKSEVE 375
K E E+S S KSE+E
Sbjct: 728 RKIKEFEESFQSLKLKKSEIE 748
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/157 (22%), Positives = 68/157 (43%), Gaps = 33/157 (21%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALD---EIAENVEVINQHQEVD 308
QEL+ + +++++V LK++E+ + V LR L+ ++A V + + +E+D
Sbjct: 228 QELKKAEEKDSLERELSQVVTKLKELENLEKEVEKLREKLEFSRKVAPYVPIAKRIEEID 287
Query: 309 -------AAKANTDREMESLREQL-----------------------ESEMESLAEKEQE 338
K +E+ L+++L E E+E +K QE
Sbjct: 288 KKLTELKVRKNKLTKELAVLKDELSFAQEELNRIEAEKEKFKEEKEREKELEHRLKKLQE 347
Query: 339 VADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVE 375
+ +I K + ++S LKE E + + +Q VE
Sbjct: 348 IKEILKELSQLSSSLKEKEREYEQAKQEFEDLSERVE 384
Score = 38.5 bits (88), Expect = 0.029
Identities = 29/129 (22%), Positives = 65/129 (49%), Gaps = 14/129 (10%)
Query: 260 MHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREME 319
+ + K+K+ + +A+LKD +++ + L+ I E + +E + + ++++
Sbjct: 293 LKVRKNKLTKELAVLKD------ELSFAQEELNRIEAEKEKFKEEKEREKELEHRLKKLQ 346
Query: 320 SLRE---QLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM-----LSSK 371
++E +L SL EKE+E K+ ++S+R+++ + AE E+ + L S+
Sbjct: 347 EIKEILKELSQLSSSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKLEKIKELFSE 406
Query: 372 SEVENLHRK 380
E +L K
Sbjct: 407 EEYTSLKMK 415
Score = 37.0 bits (84), Expect = 0.085
Identities = 35/149 (23%), Positives = 69/149 (45%), Gaps = 15/149 (10%)
Query: 233 HLESLVLRSYYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRV-------- 284
H E L R +E + E +S+ K K+ EL I + +S + V
Sbjct: 665 HFEELSSRKSKLEGELSALNE-SINSLEEERKEKLKELANIYEVAKSPREVVELYLGDKE 723
Query: 285 AWLRSALDEIAENVEVIN-QHQEVDAAKANTD--REMESLREQLESEMESLAEKEQEVAD 341
A L + E E+ + + + E++ + RE+ ++ + ES L EK +++ +
Sbjct: 724 AELERKIKEFEESFQSLKLKKSEIEEKLKEYEGIRELSDIKGEYESVKTQLEEKHKKLGE 783
Query: 342 IKKRIPEISDRLK---ELELKSAELEQSM 367
+K+ + + +RLK EL+ + +ELE+ +
Sbjct: 784 VKRELEHLGERLKRKEELQKEISELEKKL 812
Score = 37.0 bits (84), Expect = 0.085
Identities = 31/116 (26%), Positives = 58/116 (49%), Gaps = 10/116 (8%)
Query: 275 KDVESAQLRVAWLRSALD----EIAENVEVINQHQEVDAAKANTDREMESLREQLESEME 330
K E AQ ++ ++ L+ +I E ++ + +E+ + D E ESL+E++
Sbjct: 592 KQKEEAQAKLHKAQTELELLKEKIREKSRLVKEFKELYRVERLEDYE-ESLKEEINYINS 650
Query: 331 SLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRKSLIDEL 386
L E E++ ++K E+S R +LE + + L +S+ S + E RK + EL
Sbjct: 651 KLQEIEEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEE-----RKEKLKEL 701
Score = 32.7 bits (73), Expect = 1.6
Identities = 24/83 (28%), Positives = 45/83 (53%), Gaps = 13/83 (15%)
Query: 303 QHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPE-ISDRLKELELKSA 361
+ +E+D +++ SL+E++E + EV +++K IPE + +R+K+LE
Sbjct: 519 EEREIDTTLKLYAQKINSLKEEME-------KLRNEVEELRKEIPENLKERIKKLE--EL 569
Query: 362 ELEQSMLSSKSEVENLHRKSLID 384
+E+ L K N +RK+L D
Sbjct: 570 RIEKEKLEHKL---NKYRKALED 589
>SMC4_MICAR (Q9ERA5) Structural maintenance of chromosomes 4-like 1
protein (Chromosome-associated polypeptide C) (XCAP-C
homolog) (Fragment)
Length = 1243
Score = 46.6 bits (109), Expect = 1e-04
Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAK 311
+E + + + S E + K+ E + + +++E +EV ++ ++
Sbjct: 408 KEKEEKKLKEVMDSLKQETQGLQKEKEDQEKELMGFNKSVNEARSKMEVAQSELDIYLSR 467
Query: 312 ANTD-REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
NT ++ +E L + E+L E++ + +I ++P+ LKE E + +L Q ++
Sbjct: 468 HNTAVSQLSKAKETLITASETLKERKAAIGEINTKLPQTQQELKEKEKELQKLTQEEINL 527
Query: 371 KSEVENLHRK 380
KS V +L +K
Sbjct: 528 KSLVHDLFQK 537
Score = 33.9 bits (76), Expect = 0.72
Identities = 25/118 (21%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 260 MHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREME 319
+H T +IN + +++ Q ++ + LDE A + + A DR +
Sbjct: 842 LHDTIIEINN-----RKLKAQQNKLDMINKQLDECASAIT------KAQVAIKTADRNLI 890
Query: 320 SLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENL 377
++ + + + + E+E D+K + I D+ +E+ K+ E+S+ + E NL
Sbjct: 891 KAQDSVVRTEKEIKDTEKETNDLKAELKAIEDKAEEVIKKTNAAEESLPEIQKEHRNL 948
>RA50_SULAC (O33600) DNA double-strand break repair rad50 ATPase
Length = 886
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/132 (25%), Positives = 70/132 (52%), Gaps = 14/132 (10%)
Query: 260 MHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQ-------EVDAAKA 312
+ + KI E+ LKD E + R + + + E+ EN E IN ++D+ K+
Sbjct: 250 LSVVNKKIEEIALRLKDFEEKEKRYNKIETEVKELDENREKINTISSFKSILVQIDSLKS 309
Query: 313 N---TDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLK---ELELKSAELEQS 366
+ +++ +E+L+ + E L EKE++ +I+KR E+ ++ K E+E + + ++
Sbjct: 310 QINVVENDLKRKKEKLKRKKE-LEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKN 368
Query: 367 MLSSKSEVENLH 378
+ K+E+E L+
Sbjct: 369 IERQKNEIEKLN 380
Score = 37.4 bits (85), Expect = 0.065
Identities = 35/139 (25%), Positives = 67/139 (48%), Gaps = 13/139 (9%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAW-LRSALDEIAENVEVINQHQEVDA 309
VQ L+ + + +++IN L+ +++E+ + ++ L+ E + + Q ++
Sbjct: 458 VQLLELNKQITALQARINSLIKEREELEATRNKLQLELQKRSKEKGIYEAKLKELQRLEE 517
Query: 310 AKANTDREMESLREQLESEMESLAEKEQEVAD-----------IKKRIPEISDRLKELEL 358
K E+ SL E E++AEKE+E+ D +++ I E RL EL
Sbjct: 518 EKNKLQNEILSLLSY-HQEFENIAEKEKELIDYHEEYLKNSDILEEDIQEQEQRLNELNS 576
Query: 359 KSAELEQSMLSSKSEVENL 377
K +ELE+S K++ + L
Sbjct: 577 KLSELEKSYNDYKAKYQFL 595
Score = 31.2 bits (69), Expect = 4.7
Identities = 25/116 (21%), Positives = 58/116 (49%), Gaps = 7/116 (6%)
Query: 258 SIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIA---ENVEVINQHQEVDAAKANT 314
S++ + +I L +I ++ + + L+ ++EI EN+E + +E + + NT
Sbjct: 172 SLIKVLTDRIRSLQSIKDILKREEAEIDRLKKEIEEIKVKLENIEREAKEKEDELNQYNT 231
Query: 315 D----REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQS 366
+ +E++ + L E+ + +K +E+A K E R ++E + EL+++
Sbjct: 232 EFNRIKEIKVQYDILSGELSVVNKKIEEIALRLKDFEEKEKRYNKIETEVKELDEN 287
>SMC4_HUMAN (Q9NTJ3) Structural maintenance of chromosomes 4-like 1
protein (Chromosome-associated polypeptide C) (hCAP-C)
(XCAP-C homolog)
Length = 1288
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 1/130 (0%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAK 311
+E + + + S E + K+ ES + + +++E ++V ++ ++
Sbjct: 453 KEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSR 512
Query: 312 ANTD-REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
NT ++ +E L + E+L E++ + DI+ ++P+ LKE E + +L Q +
Sbjct: 513 HNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNF 572
Query: 371 KSEVENLHRK 380
KS V +L +K
Sbjct: 573 KSLVHDLFQK 582
>RA50_PYRHO (O58687) DNA double-strand break repair rad50 ATPase
Length = 879
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/130 (23%), Positives = 62/130 (46%), Gaps = 12/130 (9%)
Query: 249 FVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
++V++ + + + + +++ E+ +KD ES R+ W+ L EI E + +
Sbjct: 308 YLVKKNELEKRLGILSNRLQEVKRKIKDAESKVARIRWIEERLKEIQEKIMKLEPRVREF 367
Query: 309 AAKANTDREMESLREQLES-EMESLAEK-----------EQEVADIKKRIPEISDRLKEL 356
+MESL+ +L E E + EK E+E+ I ++I E++ R K+
Sbjct: 368 EDAMRLKAQMESLKSKLGGLEPEKINEKLLYLENRKKELEEEIDKITRKIGELNQRSKDR 427
Query: 357 ELKSAELEQS 366
L EL+++
Sbjct: 428 RLAIIELKKA 437
Score = 38.9 bits (89), Expect = 0.022
Identities = 29/129 (22%), Positives = 61/129 (46%), Gaps = 8/129 (6%)
Query: 254 LQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVI----NQHQEVDA 309
+++++I L +++ +L ++ + + LR L+ I E V+ + N E+
Sbjct: 189 MKTENIEDLIRTQEKSFTEVLNEIRNISSNLPRLRRELEGIKEEVKTLEATFNSITELKL 248
Query: 310 AKANTDREMESLRE---QLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQS 366
+ + L E QLES +E +K +E+ ++ K +PE+ + E + E +
Sbjct: 249 RLGELNGKKGRLEERIRQLESGIEEKRKKSKELEEVVKELPELEKKETEYR-RLIEFKDE 307
Query: 367 MLSSKSEVE 375
L K+E+E
Sbjct: 308 YLVKKNELE 316
Score = 38.9 bits (89), Expect = 0.022
Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 23/184 (12%)
Query: 209 HVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFVVQELQSDSIMHLTKSKIN 268
HV E+ + S +D+ I + L ++ +R I+ + L+SD T+ KI
Sbjct: 107 HVTETSMESVSSFIDRI--IPYNVFLNAIYVRQGQIDAI------LESDE----TRDKIV 154
Query: 269 ELVAILKDVESAQLRVAWLRS----ALDEI------AENVEVINQHQEVDAAKA-NTDRE 317
+ + L +E A + +R +++E EN+E + + QE + N R
Sbjct: 155 KEILNLDKLEKAYDNLGKIRKYIKYSIEEKEKFIMKTENIEDLIRTQEKSFTEVLNEIRN 214
Query: 318 MESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENL 377
+ S +L E+E + E+ + + I E+ RL EL K LE+ + +S +E
Sbjct: 215 ISSNLPRLRRELEGIKEEVKTLEATFNSITELKLRLGELNGKKGRLEERIRQLESGIEEK 274
Query: 378 HRKS 381
+KS
Sbjct: 275 RKKS 278
Score = 38.1 bits (87), Expect = 0.038
Identities = 40/158 (25%), Positives = 73/158 (45%), Gaps = 25/158 (15%)
Query: 238 VLRSYYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAEN 297
+LR Y +E + + +E+Q K+ +L A + VE+ R++ L++ D+I E
Sbjct: 456 LLRKYSLE-LSSIEKEIQE------AKALERQLRAEFRKVENELSRLSSLKTIADQIIEI 508
Query: 298 VEVINQHQEVDAAKANTDREM-ESLREQLESEMESLAEKEQEVAD--------------I 342
E +++ D + + E+ +S +L+ E+ESL ++ E+ D
Sbjct: 509 RERLSKINLEDLKRDKEEYELLKSESNKLKGEVESLKKEVNELNDYKNESTKLEIEIDKA 568
Query: 343 KKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
KK + EI DRL L K+ + + E+E H K
Sbjct: 569 KKELSEIEDRLLRLGFKTID---ELSGRIRELEKFHNK 603
Score = 31.6 bits (70), Expect = 3.6
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 209 HVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFVVQELQSDSIMHLTKSKIN 268
+ ++ ILES+ D+ ++ + E L IE V + ELQ + K
Sbjct: 609 NAEKELRDILESLKDEREELDKA--FEELAKIETDIEKVTSQLNELQRKFDQKKYEEKRE 666
Query: 269 ELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLESE 328
+++ + +++ + ++ L DEI +E + + ++ RE + E
Sbjct: 667 KMMKLSMEIKGLETKLEELERRRDEIKSTIEKLKEERKE--------------RESAKME 712
Query: 329 MESLAEKEQEVADIKKRIPEISDRLKELEL-KSAELEQSMLS 369
+E L + + +++ +I E +KE L K E+ + S
Sbjct: 713 LEKLNIAIKRIEELRGKIKEYKALIKEEALNKIGEIASEIFS 754
Score = 31.6 bits (70), Expect = 3.6
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 185 NEDNDDKGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYI 244
+E N KG+ ES+ E V + + ++ ++ LE +DK + L L I
Sbjct: 532 SESNKLKGEVESLKKE----VNELNDYKNESTKLEIEIDKAKKELSEIEDRLLRLGFKTI 587
Query: 245 ECVCFVVQELQSDSIMHL-TKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQ 303
+ + ++EL+ ++ K+ EL IL+ ++ + + L +I ++E +
Sbjct: 588 DELSGRIRELEKFHNKYIEAKNAEKELRDILESLKDEREELDKAFEELAKIETDIEKVTS 647
Query: 304 H-----QEVDAAKANTDRE-MESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELE 357
++ D K RE M L +++ L E E+ +IK I ++ + KE E
Sbjct: 648 QLNELQRKFDQKKYEEKREKMMKLSMEIKGLETKLEELERRRDEIKSTIEKLKEERKERE 707
Query: 358 LKSAELEQSMLSSKSEVENLHRK 380
ELE+ ++ K +E L K
Sbjct: 708 SAKMELEKLNIAIK-RIEELRGK 729
Score = 30.4 bits (67), Expect = 8.0
Identities = 25/114 (21%), Positives = 51/114 (43%), Gaps = 13/114 (11%)
Query: 264 KSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLRE 323
K ++ L A + +LR+ L + E + + E K +E+E + +
Sbjct: 230 KEEVKTLEATFNSITELKLRLGELNGKKGRLEERIRQLESGIE---EKRKKSKELEEVVK 286
Query: 324 QL------ESEMESLAEKEQEVA----DIKKRIPEISDRLKELELKSAELEQSM 367
+L E+E L E + E +++KR+ +S+RL+E++ K + E +
Sbjct: 287 ELPELEKKETEYRRLIEFKDEYLVKKNELEKRLGILSNRLQEVKRKIKDAESKV 340
>EEA1_MOUSE (Q8BL66) Early endosome antigen 1 (Fragment)
Length = 790
Score = 45.4 bits (106), Expect = 2e-04
Identities = 45/202 (22%), Positives = 89/202 (43%), Gaps = 25/202 (12%)
Query: 191 KGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFV 250
KG + +++ K K+ + LE +K+ + AS L ++C
Sbjct: 138 KGSINELTQKNQNLTEKLQKKDLDYTHLE---EKHNEESASRKTLQASLHQRDLDCQQLQ 194
Query: 251 VQELQSDSIMHLTKSKINE-------LVAILKDVESAQLRVAWLRSALDEIAENVEVINQ 303
+ S+S + + +++E L L++VES + L+ + ++ + E Q
Sbjct: 195 ARLTASESSLQRAQGELSEKAEAAQKLREELREVESTRQH---LKVEVKQLQQQREEKEQ 251
Query: 304 H--------QEVDAAKANTDREMES----LREQLESEMESLAEKEQEVADIKKRIPEISD 351
H ++ T+R++ L+EQ + E L EKEQ+VAD++ ++ + +
Sbjct: 252 HGLQLQGEVSQLHCKLLETERQLGEAHGRLKEQRQLSSEKLMEKEQQVADLQLKLSRLEE 311
Query: 352 RLKELELKSAELEQSMLSSKSE 373
+LKE S EL+ + SK +
Sbjct: 312 QLKEKVTNSTELQHQLEKSKQQ 333
Score = 34.3 bits (77), Expect = 0.55
Identities = 49/239 (20%), Positives = 106/239 (43%), Gaps = 25/239 (10%)
Query: 172 SIDFSFSGIIPQGNEDNDD--------KGDTESVVS-ESRVPVGKYHVKESFASILESIL 222
S++ S S + Q NE + K TE ++S E+ + ++ + ++
Sbjct: 462 SLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKAAQRADLQNHLDTAQHALQ 521
Query: 223 DKYGDIG-ASCHLESLVLRSYYIECVCFVVQE-LQSDSIMHLT-KSKINELVAILKDVES 279
DK ++ S L+ L + + C ++ L+ HL+ + K+ +L +K +E+
Sbjct: 522 DKQQELNKVSVQLDQLTAKFQEKQEHCIQLESHLKDHKEKHLSLEQKVEDLEGHIKKLEA 581
Query: 280 AQLRV-AWLRSALDEIAE-----------NVEVINQHQEVDAAKANTDREMESLREQLES 327
L V A AL + + N E+ + QE + + T ++++ E LE+
Sbjct: 582 DALEVKASKEQALQSLQQQRQLSTDLELRNAELSRELQEQEEVVSCTKLDLQNKSEILEN 641
Query: 328 EMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRKSLIDEL 386
++L +KE+E +K+ ++S K + + Q+ ++ + V+ + +L+ EL
Sbjct: 642 IKQTLTKKEEENVVLKQEFEKLSQDSKTQHKELGDRMQAAVTELTAVK-AQKDALLAEL 699
Score = 33.5 bits (75), Expect = 0.94
Identities = 18/81 (22%), Positives = 40/81 (49%)
Query: 305 QEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELE 364
Q++ A ++ ++ + +L + E+ + +E+ +++ + +K+L+ + E E
Sbjct: 191 QQLQARLTASESSLQRAQGELSEKAEAAQKLREELREVESTRQHLKVEVKQLQQQREEKE 250
Query: 365 QSMLSSKSEVENLHRKSLIDE 385
Q L + EV LH K L E
Sbjct: 251 QHGLQLQGEVSQLHCKLLETE 271
Score = 32.7 bits (73), Expect = 1.6
Identities = 21/113 (18%), Positives = 51/113 (44%), Gaps = 8/113 (7%)
Query: 275 KDVESAQLRVAWLRSALDEIAENVEVIN--------QHQEVDAAKANTDREMESLREQLE 326
+ V QL+++ L L E N + QHQE A + + ++ + LE
Sbjct: 297 QQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSATAKLREAQNDLE 356
Query: 327 SEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHR 379
+ + +K+Q++ +++ + + + + LE + +L + + + E L++
Sbjct: 357 QVLRQIGDKDQKIQNLEALLQKGKESVSLLEKEREDLYAKIQAGEGETAVLNQ 409
>TPM2_YEAST (P40414) Tropomyosin 2
Length = 161
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 23/140 (16%)
Query: 260 MHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAE-NVEVINQHQEVDAAKANTDREM 318
M K K+N L + ES Q + LR L E+ + N E N+ + + A D E+
Sbjct: 1 MEKIKEKLNSLKL---ESESWQEKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEV 57
Query: 319 ESLREQLESEMESLAEK------------------EQEVADIKKRIPEISDRLKELELKS 360
E L QL S+ + LAE EQ++ D + ++ E D+LKE +L S
Sbjct: 58 EKLESQL-SDTKQLAEDSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNS 116
Query: 361 AELEQSMLSSKSEVENLHRK 380
++ + +++ + E + +K
Sbjct: 117 EQMGRRIVALEEERDEWEKK 136
>SCP1_HUMAN (Q15431) Synaptonemal complex protein 1 (SCP-1 protein)
Length = 976
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/116 (26%), Positives = 62/116 (52%), Gaps = 5/116 (4%)
Query: 273 ILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLESEMESL 332
+LK +E+ Q LR+ L+ + E E+ + EV ++ +LR+Q+E++ + +
Sbjct: 558 MLKQIENLQETETQLRNELEYVRE--ELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYI 615
Query: 333 AEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSK---SEVENLHRKSLIDE 385
E +QE +KK+ S +L E+K +LE + S+K E+ + ++K + D+
Sbjct: 616 EELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDK 671
Score = 31.2 bits (69), Expect = 4.7
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Query: 281 QLRVAWLRSALD---EIAENVEVINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQ 337
+LRV S L+ ++ E+ E I QH E + K D+E +Q+ + + EKE
Sbjct: 227 ELRVQAENSRLEMHFKLKEDYEKI-QHLEQEYKKEINDKE-----KQVSLLLIQITEKEN 280
Query: 338 EVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRKSLID 384
++ D+ + E D++ +LE K+ +L+ L E ++ K L D
Sbjct: 281 KMKDLTFLLEESRDKVNQLEEKT-KLQSENLKQSIEKQHHLTKELED 326
Score = 30.8 bits (68), Expect = 6.1
Identities = 16/84 (19%), Positives = 42/84 (49%)
Query: 298 VEVINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELE 357
+E+ NQ ++++ K +R ++ + E+E + E E ++K++ E+ +L + E
Sbjct: 539 LELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSE 598
Query: 358 LKSAELEQSMLSSKSEVENLHRKS 381
L + + + +E L +++
Sbjct: 599 ENCNNLRKQVENKNKYIEELQQEN 622
>RA50_METJA (Q58718) DNA double-strand break repair rad50 ATPase
Length = 1005
Score = 44.7 bits (104), Expect = 4e-04
Identities = 23/90 (25%), Positives = 51/90 (56%), Gaps = 3/90 (3%)
Query: 268 NELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLES 327
N+++ + K++ + R++++ LDEI N E +H+++ N +E++++REQ
Sbjct: 756 NKILEVNKEINDIEERISYINQKLDEINYNEE---EHKKIKELYENKRQELDNVREQKTE 812
Query: 328 EMESLAEKEQEVADIKKRIPEISDRLKELE 357
+ +++V +K R+ E+S+ KE E
Sbjct: 813 IETGIEYLKKDVESLKARLKEMSNLEKEKE 842
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/179 (23%), Positives = 85/179 (47%), Gaps = 10/179 (5%)
Query: 218 LESILDKYGDIGASCHLESLVLRSYYIECVCFVVQELQSDSIMHLTK-----SKINELVA 272
LE+ ++K + + +ES+ IE V++ LQ + I K S+I L
Sbjct: 431 LETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKIELNKKLGEINSEIKRLKK 490
Query: 273 ILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLESEMESL 332
IL +++ + + ++ +DE + +E+INQH+ K E+ ++E ++E L
Sbjct: 491 ILDELKEVEGKCPLCKTPIDE-NKKMELINQHKTQLNNKYTELEEINKKIREIEKDIEKL 549
Query: 333 A---EKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVEN-LHRKSLIDELL 387
+KE+ + +K E +++ELELK ++ + ++ N + +DE+L
Sbjct: 550 KKEIDKEENLKTLKTLYLEKQSQIEELELKLKNYKEQLDEINKKISNYVINGKPVDEIL 608
Score = 34.3 bits (77), Expect = 0.55
Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Query: 269 ELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLESE 328
E + +L++ +S + + L + ++++ E + I+ ++ K E + + E L+ E
Sbjct: 413 EYITLLQEKKSIEKNINDLETRINKLLEETKNIDIESIENSLKEI--EEKKKVLENLQKE 470
Query: 329 MESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM-LSSKSEVENLHRKSL 382
L +K E+ KR+ +I D LKE+E K + + + K E+ N H+ L
Sbjct: 471 KIELNKKLGEINSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQL 525
Score = 30.4 bits (67), Expect = 8.0
Identities = 25/108 (23%), Positives = 52/108 (48%), Gaps = 14/108 (12%)
Query: 249 FVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
+V+ D I+ KS++N+ SA V++L S +E + N+ +E++
Sbjct: 597 YVINGKPVDEILEDIKSQLNKFKNFYNQYLSA---VSYLNSVDEE-----GIRNRIKEIE 648
Query: 309 AAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKEL 356
+ ++E + E+ L E E+E+ +K ++ E+ ++ KEL
Sbjct: 649 NIVSGWNKE------KCREELNKLREDEREINRLKDKLNELKNKEKEL 690
>KTN1_HUMAN (Q86UP2) Kinectin (Kinesin receptor) (CG-1 antigen)
Length = 1357
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/127 (25%), Positives = 69/127 (53%), Gaps = 5/127 (3%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAA 310
V+EL ++ + +K EL AI + S V L++ ++ ++ + ++V
Sbjct: 747 VEELLETGLIQVA-TKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHE 805
Query: 311 KANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
K D +++S+ E LE+E+ +A KE+ V D+K+ I + + + ++L+ A+ + S+ S
Sbjct: 806 K---DGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQ-QLSITSK 861
Query: 371 KSEVENL 377
E++NL
Sbjct: 862 VQELQNL 868
Score = 32.7 bits (73), Expect = 1.6
Identities = 61/287 (21%), Positives = 118/287 (40%), Gaps = 61/287 (21%)
Query: 132 EDQQKNGVEHLANPIQTKQED-KTASDVHPGEGLATTFKGGSIDFSFSGIIPQGNEDNDD 190
E K+ VE + IQ K E KT ++ ++ + + E N
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEEL--------------LETGLIQVATKEEELNAI 768
Query: 191 KGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFV 250
+ + S+ E + K + + SFAS++E ++ H + ++S V
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVE-------ELKKVIHEKDGKIKS--------V 813
Query: 251 VQELQSDSIMHLTKSKI-----NELVAILKDVESAQLRVAWLRSALDEIAENVEVIN-QH 304
+ L+++ + K K E+ A+ +++ + QL A S ++ E ++ +
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 305 QEVDAAKANTDREMESLR------EQLESEMESLAEKEQEVADIKKRIPEISDRLKELEL 358
++++ KA + + + L + L+ E ESL QEVA + + + +ELE+
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 359 KSAELE-------------QSMLSSKSEV------ENLHRKSLIDEL 386
E E +S LSSK+++ EN KS I++L
Sbjct: 934 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQL 980
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/129 (22%), Positives = 61/129 (46%), Gaps = 20/129 (15%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVA-WLRSALDE---IAENVEVINQHQE 306
VQELQ+ ++ + ++N + A+L++ E WL+ +E + +V+ + QH
Sbjct: 862 VQELQN--LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNL 919
Query: 307 VDAAKA--------------NTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDR 352
+A+ A N + +E++ ++ ES++ S + Q+V D K ++
Sbjct: 920 KEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQ 979
Query: 353 LKELELKSA 361
LK+ + A
Sbjct: 980 LKQQNYQQA 988
Score = 31.6 bits (70), Expect = 3.6
Identities = 65/302 (21%), Positives = 125/302 (40%), Gaps = 38/302 (12%)
Query: 66 EPPVVAGAVPAAKVEAIQKSNASSPISNHSEIKKVESRNDDHNHSVPVSGQIHVPLPVPD 125
E ++ A ++ AI+ N+S E++ ++++ +D Q+ V +
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLT----KEVQDLKAKQND---------QVSFASLVEE 798
Query: 126 VKHV-HEEDQQKNGVEHL--ANPIQTKQEDKTASDVHPGEGLATTFKGGSIDFSFSGIIP 182
+K V HE+D + VE L A ++ ++KT D+ E A + G++
Sbjct: 799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQ-EIKALKEEIGNVQL------- 850
Query: 183 QGNEDNDDKGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSY 242
E T V + GK + ++LE + G L+ L +
Sbjct: 851 ---EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGK--WLQDLQEEN- 904
Query: 243 YIECVCFVVQELQSDSIMHLTK-SKINELVAILKDVESAQLRV-AWLRSALDEIAENVEV 300
E + VQE+ ++ + S+ EL +LK+ E+ R+ A L+ +++ ++
Sbjct: 905 --ESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQL 962
Query: 301 INQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELE-LK 359
+ Q+V ++E L++Q + S E+ + I +R EIS EL+ LK
Sbjct: 963 L---QDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLK 1019
Query: 360 SA 361
A
Sbjct: 1020 DA 1021
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 44.3 bits (103), Expect = 5e-04
Identities = 41/146 (28%), Positives = 78/146 (53%), Gaps = 16/146 (10%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVE------SAQLRVAWLRSALDEIAENVEVINQHQ 305
+++Q + TK ++N L A L+ +E +AQL+ + A E N E+ +
Sbjct: 1125 EKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLND 1184
Query: 306 EVDAAKANTDREMESLR---EQLESEMESLAEKEQEVADIKK-RIPEISDRLKELELKSA 361
E+ +T +E ES++ ++LE E++++ +E +++KK I ++ ++KEL+ K+
Sbjct: 1185 EI----TSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNE 1240
Query: 362 ELEQSMLSSKSEVEN--LHRKSLIDE 385
E S+L S VE+ + K L DE
Sbjct: 1241 TNEASLLESIKSVESETVKIKELQDE 1266
Score = 38.9 bits (89), Expect = 0.022
Identities = 41/146 (28%), Positives = 76/146 (51%), Gaps = 29/146 (19%)
Query: 263 TKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQE-VDAAKANTDREMESL 321
T+S++ E V++ D E + + ++S DEI + I ++ E + + + + R++ESL
Sbjct: 1411 TRSEL-EKVSLSND-ELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESL 1468
Query: 322 REQLESEMES-------LAEKEQEVADIKKRIPEISDRLKEL---------ELKSA---- 361
+EQL + ES L + E+E + K + + + +K+L ELKS+
Sbjct: 1469 KEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETI 1528
Query: 362 -----ELEQSMLSSKSEVENL-HRKS 381
+LEQS S++ +++NL H KS
Sbjct: 1529 RKSDEKLEQSKKSAEEDIKNLQHEKS 1554
Score = 38.5 bits (88), Expect = 0.029
Identities = 37/138 (26%), Positives = 68/138 (48%), Gaps = 17/138 (12%)
Query: 257 DSIMHLTKSKIN---ELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKAN 313
+ I LTK++ EL A + ++ AL E+ EN E + + K
Sbjct: 1075 NKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEE------KIQ 1128
Query: 314 TDREMESLREQLES---EMESLAEKEQE--VADIKKRIPEISDRLKELELKSAELEQSML 368
++E ++QL S +ESL EKE E A +KK +I+++ ++ + ++L +
Sbjct: 1129 LEKEATETKQQLNSLRANLESL-EKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEIT 1187
Query: 369 SSKSEVENLHRKSLIDEL 386
S++ E E++ +K+ DEL
Sbjct: 1188 STQQENESIKKKN--DEL 1203
Score = 35.8 bits (81), Expect = 0.19
Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Query: 261 HLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQE-----VDAAKANTD 315
H++K ELV +S VA L L +A N + + E V+ +K +
Sbjct: 938 HISK----ELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESS 993
Query: 316 REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVE 375
++ +L+ +++S + + E I+K I ++ + +LE E+ SSK E E
Sbjct: 994 IQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYE 1053
Query: 376 NLHRKSLIDELL 387
+ + SL+ E L
Sbjct: 1054 S--QISLLKEKL 1063
Score = 34.7 bits (78), Expect = 0.42
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 11/135 (8%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAA 310
+Q +SD I + +S+ KD+E + ++ + E+ + +N QE
Sbjct: 1549 LQHEKSDLISRINESE--------KDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRI 1600
Query: 311 KANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
A + ++S E +E E++ +K+ E+ ++ ++ RLKELE + +Q S
Sbjct: 1601 NAEENTVLKSKLEDIERELK---DKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKS 1657
Query: 371 KSEVENLHRKSLIDE 385
+ E RK +++
Sbjct: 1658 EEERRAEVRKFQVEK 1672
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 7/119 (5%)
Query: 264 KSKINELVAILKDVESAQLRVAWLR-SALDEIAENVEVINQHQEVDAAKANTDREMESLR 322
K K +EL +K ++S + L+ S +D + ++ + + E + A +ES++
Sbjct: 1197 KKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASL-----LESIK 1251
Query: 323 EQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRKS 381
+ESE + E + E +K + E+ D+LK E K+++ + S+ E L K+
Sbjct: 1252 S-VESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKT 1309
>KTN1_VULVU (O97961) Kinectin
Length = 1330
Score = 43.9 bits (102), Expect = 7e-04
Identities = 32/127 (25%), Positives = 69/127 (54%), Gaps = 5/127 (3%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAA 310
V+EL ++ + +K EL AI + S V L++ ++ ++ + ++V
Sbjct: 747 VEELLETGLIQVA-TKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHE 805
Query: 311 KANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
K D +++S+ E LE+E+ +A KE+ + D+K+ I + + + ++L+ A+ + S+ S
Sbjct: 806 K---DGKIKSVEELLEAEVLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQ-QLSITSQ 861
Query: 371 KSEVENL 377
E++NL
Sbjct: 862 IQELQNL 868
Score = 40.0 bits (92), Expect = 0.010
Identities = 31/123 (25%), Positives = 67/123 (54%), Gaps = 13/123 (10%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVES-AQLRVAWLRSALDE---IAENVEVINQHQE 306
+QELQ+ ++ + ++N + +L++ E R WL+ +E + +++ + QH
Sbjct: 862 IQELQN--LLKGKEEQMNTMKTVLEEKEKDLASRGKWLQDLQEENESLKTHIQEVAQHNL 919
Query: 307 VDAAKANTDREMESLREQLESEMES----LAEKEQEVADIKKRIPEISDRLKELELKSAE 362
+A A+ E+E++ ++ E+EM+ L E+E +++ K + E+ D E +L +E
Sbjct: 920 KEACSASRLEELETVLKEKENEMKRIETILKERENDLSSKIKLLQEVQD---ENKLFKSE 976
Query: 363 LEQ 365
+EQ
Sbjct: 977 IEQ 979
Score = 32.7 bits (73), Expect = 1.6
Identities = 60/260 (23%), Positives = 108/260 (41%), Gaps = 42/260 (16%)
Query: 121 LPVPDVKHVHEEDQQKNGVEHLANPIQTKQED-KTASDVHPGEGLATTFKGGSIDFSFSG 179
L V ++ + E K+ VE + IQ K E KT ++ ++
Sbjct: 712 LEVQKLQILVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL--------------LETGLIQ 757
Query: 180 IIPQGNEDNDDKGDTESVVSESRVPVGKYHVKESFASILES----ILDKYGDIGASCHL- 234
+ + E N + + S+ E + K + + SFAS++E I +K G I + L
Sbjct: 758 VATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Query: 235 ESLVLRSYYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEI 294
E+ VL+ E +Q+L+ E+ A+ +++ + QL A S +I
Sbjct: 818 EAEVLKVANKEKT---IQDLKQ------------EIEALKEEIGNIQLEKAQQLSITSQI 862
Query: 295 AENVEVIN-QHQEVDAAKANTDREMESLR------EQLESEMESLAEKEQEVADIKKRIP 347
E ++ + ++++ K + + + L + L+ E ESL QEVA +
Sbjct: 863 QELQNLLKGKEEQMNTMKTVLEEKEKDLASRGKWLQDLQEENESLKTHIQEVAQHNLKEA 922
Query: 348 EISDRLKELELKSAELEQSM 367
+ RL+ELE E E M
Sbjct: 923 CSASRLEELETVLKEKENEM 942
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein)
(Myosin II) (Non-muscle MHC)
Length = 2057
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/116 (27%), Positives = 57/116 (48%), Gaps = 9/116 (7%)
Query: 265 SKINELVAILKDVESAQLR---VAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESL 321
+K+ L+ + K E + + +R LD +A+N QE + E +L
Sbjct: 923 TKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNT------QEYERKYQQALVEKTTL 976
Query: 322 REQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENL 377
EQL++E+E AE E+ + + R E+ D ++ELE + E E+ +L+ E + L
Sbjct: 977 AEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKL 1032
Score = 37.4 bits (85), Expect = 0.065
Identities = 29/132 (21%), Positives = 64/132 (47%), Gaps = 8/132 (6%)
Query: 253 ELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQH-QEVDAAK 311
EL++ + + + ++L + +E + L S L +I E + + +E D AK
Sbjct: 1384 ELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAK 1443
Query: 312 ANTDR-------EMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELE 364
N +R +M+ ++++ E + + E E+ + K I + ++KEL ++ L+
Sbjct: 1444 RNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLD 1503
Query: 365 QSMLSSKSEVEN 376
+S +SE+E+
Sbjct: 1504 KSKKKIQSELED 1515
Score = 37.4 bits (85), Expect = 0.065
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 23/147 (15%)
Query: 262 LTKSKINELVAILKDVESAQLRVAWLRS----ALDEIAENVEVINQH-QEVDAAKANTDR 316
L + + N+L L + E +A L++ + E+ E + Q QE D +K +
Sbjct: 1087 LLEERANDLSQTLAEEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIET 1146
Query: 317 EMESLREQLES------EMES-LAEKEQEVADIKKRIPEIS-------DRLKELELKSAE 362
E+ L+EQL EM++ LA++E+E+ RI E S +ELE + AE
Sbjct: 1147 EVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAE 1206
Query: 363 LEQSMLSSK---SEVENLHRKSLIDEL 386
+++ + + K ++ E + R+ L +EL
Sbjct: 1207 IQEDLEAEKAARAKAEKV-RRDLSEEL 1232
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/121 (19%), Positives = 63/121 (51%), Gaps = 9/121 (7%)
Query: 261 HLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMES 320
H ++N + L+++ A+ + + L+ AEN ++ + + V++++ DR +
Sbjct: 1283 HKHSQELNSINDQLENLRKAKTVLEKAKGTLE--AENADLATELRSVNSSRQENDRRRKQ 1340
Query: 321 LREQLESEMESLAEKEQEVADIKKRIPE-------ISDRLKELELKSAELEQSMLSSKSE 373
Q+ LAE E+ ++++++ + I+++L+E ELK++ +S + +S+
Sbjct: 1341 AESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQ 1400
Query: 374 V 374
+
Sbjct: 1401 L 1401
Score = 35.8 bits (81), Expect = 0.19
Identities = 23/70 (32%), Positives = 39/70 (54%), Gaps = 7/70 (10%)
Query: 315 DREMESLREQLESEMES-------LAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM 367
+ E E+L+EQLE + E+ LAE ++ +IKK+ E +D KELE L + +
Sbjct: 1426 ESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDI 1485
Query: 368 LSSKSEVENL 377
+ + +V+ L
Sbjct: 1486 EALERQVKEL 1495
Score = 35.4 bits (80), Expect = 0.25
Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 291 LDEIAENVEVINQHQEV-DAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEI 349
L+ I + +E + + + V + AK + E L +L S S E ++ + +I E+
Sbjct: 1289 LNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAEL 1348
Query: 350 SDRLKELELKSAELEQSMLSSKSEVENL 377
+L E+E +EL++ + E EN+
Sbjct: 1349 QVKLAEIERARSELQEKCTKLQQEAENI 1376
Score = 34.7 bits (78), Expect = 0.42
Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 260 MHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREME 319
M K K E + K++E + R+ AL+ + E+I Q+ +D +K E+E
Sbjct: 1457 MQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVK--ELIAQNDRLDKSKKKIQSELE 1514
Query: 320 SLREQLESEMESLAEKEQEVADIKKRIPE---ISDRLKE----LELKSAELEQSMLSSKS 372
+LE++ + E E++ + K + E IS+++ + E ++ E E +LS
Sbjct: 1515 DATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSR 1574
Query: 373 EVENLHRK 380
E++ K
Sbjct: 1575 ELDEAFDK 1582
Score = 31.2 bits (69), Expect = 4.7
Identities = 33/139 (23%), Positives = 62/139 (43%), Gaps = 9/139 (6%)
Query: 244 IECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQ 303
IE + +++ D++ H K + ++ L+D E A+ L++ E V+ +
Sbjct: 1713 IETTMEMHNKVKEDALKHAKKLQA-QVKDALRDAEEAKAAKEELQALSKEADGKVKAL-- 1769
Query: 304 HQEVDAAKANTD-REMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAE 362
E + + D E R E+E + LAE E+A+ + + D + LE + A
Sbjct: 1770 --EAEVLQLTEDLASSERARRAAETERDELAE---EIANNANKGSLMIDEKRRLEARIAT 1824
Query: 363 LEQSMLSSKSEVENLHRKS 381
LE+ + +S E L +S
Sbjct: 1825 LEEELEEEQSNSEVLLDRS 1843
Score = 30.8 bits (68), Expect = 6.1
Identities = 25/111 (22%), Positives = 59/111 (52%), Gaps = 13/111 (11%)
Query: 266 KINELVAILKDVESAQLRV-AWLRSALDEI-AENVEVINQHQEVDAAKANTDR---EMES 320
++ EL+A ++ ++ ++ + L A E+ A+ +V+ E++ + N D+ E ++
Sbjct: 1491 QVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVL----ELEKKQKNFDKILAEEKA 1546
Query: 321 LREQLESEMES----LAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM 367
+ EQ+ E ++ EKE +V + + + E D++++LE K L+ +
Sbjct: 1547 ISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNEL 1597
>MYSB_CAEEL (P02566) Myosin heavy chain B (MHC B)
Length = 1966
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/204 (19%), Positives = 88/204 (42%), Gaps = 36/204 (17%)
Query: 201 SRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFVVQELQSDSIM 260
+ V G +S + ++ + D+ G+ G S H ++R E++ + +
Sbjct: 1504 AEVVEGLRRENKSLSQEIKDLTDQLGEGGRSVHEMQKIIRRL----------EIEKEELQ 1553
Query: 261 HLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMES 320
H L A V AQ+ V+ +RS +++ + E +E + + N R +ES
Sbjct: 1554 HALDEAEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKE-----EEFENTRKNHARALES 1608
Query: 321 LREQLESEMESLAE------------KEQEV---------ADIKKRIPEISDRLKELELK 359
++ LE+E + AE E E+ AD +K + ++++EL+L+
Sbjct: 1609 MQASLETEAKGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQ 1668
Query: 360 SAELEQSMLSSKSEVENLHRKSLI 383
E +++ ++ + N +++ +
Sbjct: 1669 VEEEQRNGADTREQFFNAEKRATL 1692
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/115 (26%), Positives = 63/115 (54%), Gaps = 12/115 (10%)
Query: 266 KINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQL 325
KIN+ V L+D + + + LR L+E + +++ + K + +ES + QL
Sbjct: 863 KINDKVKALEDSLAKEEK---LRKELEE--SSAKLVEE-------KTSLFTNLESTKTQL 910
Query: 326 ESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
E LA+ E + D K++ E++D+L + E ++A+++++ ++EVE L ++
Sbjct: 911 SDAEERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKKQ 965
Score = 33.9 bits (76), Expect = 0.72
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 20/135 (14%)
Query: 265 SKINELVAILKDVESAQLRVAWLRSALDEIAENV-----EVINQHQEVDAAKANTDRE-- 317
S+ +LV L+D ES ++ L+S L E E + Q V A N E
Sbjct: 1294 SENGDLVRQLEDAESQVNQLTRLKSQLTSQLEEARRTADEEARERQTVAAQAKNYQHEAE 1353
Query: 318 --MESLREQLESEMESLAEKEQEVADIKK-----------RIPEISDRLKELELKSAELE 364
ESL E++E + E L + + ADI++ + E+ D + K EL+
Sbjct: 1354 QLQESLEEEIEGKNEILRQLSKANADIQQWKARFEGEGLLKADELEDAKRRQAQKINELQ 1413
Query: 365 QSMLSSKSEVENLHR 379
+++ ++ S+ +L +
Sbjct: 1414 EALDAANSKNASLEK 1428
Score = 31.2 bits (69), Expect = 4.7
Identities = 30/131 (22%), Positives = 59/131 (44%), Gaps = 16/131 (12%)
Query: 260 MHLTKSKINELVAILKDVESAQL----RVAWLRS----ALDEIAENVEVINQHQ-EVDAA 310
+ + K + EL + +D+E A + ++ LR A+ E+ + ++ +N+ + +V+
Sbjct: 1173 VEVNKKREAELAKLRRDLEEANMNHENQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKD 1232
Query: 311 KANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSS 370
KA R+ E L QL+ E E K + +L EL+ K+ E + +
Sbjct: 1233 KAQAVRDAEDLAAQLDQETSGKLNNE-------KLAKQFELQLTELQSKADEQSRQLQDF 1285
Query: 371 KSEVENLHRKS 381
S LH ++
Sbjct: 1286 TSLKGRLHSEN 1296
Score = 31.2 bits (69), Expect = 4.7
Identities = 31/128 (24%), Positives = 64/128 (49%), Gaps = 10/128 (7%)
Query: 250 VVQELQSDSIMHLTKSKIN-ELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
++++LQS+ ++K+ +L L D+E + R R+ LD+ VE E+
Sbjct: 1018 LMEDLQSEEDKGNHQNKVKAKLEQTLDDLEDSLEREKRARADLDKQKRKVE-----GELK 1072
Query: 309 AAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSML 368
A+ N D ES R++ + E +L +KE E+ + R+ + + +L+ + + + +
Sbjct: 1073 IAQENID---ESGRQRHDLE-NNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRIS 1128
Query: 369 SSKSEVEN 376
+ E+EN
Sbjct: 1129 ELEEELEN 1136
>MYS2_DICDI (P08799) Myosin II heavy chain, non muscle
Length = 2116
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/118 (26%), Positives = 58/118 (48%), Gaps = 4/118 (3%)
Query: 263 TKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVIN-QHQEVDAAKANTDREMESL 321
TK K+N+ A E + A L +DE+ +E + + D +K + E+++L
Sbjct: 1823 TKYKLNDEAATKTQTE---IGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNL 1879
Query: 322 REQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHR 379
R Q+E E + E+E ++ + E+ + ++E E +E EQS + E+E+ R
Sbjct: 1880 RAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARR 1937
Score = 38.9 bits (89), Expect = 0.022
Identities = 29/112 (25%), Positives = 59/112 (51%), Gaps = 8/112 (7%)
Query: 277 VESAQLRVAWLRSALDEIAENVE-VINQHQEVDAAKANTDREMESLREQLESEMESLAEK 335
+ +++ ++ L + +DE+ E +E I ++ AK + E+E +R+QLE E +S +E
Sbjct: 1666 LNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSEL 1725
Query: 336 EQ-------EVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
E EV DIKK+ ++ +L+ +L + + K ++E+ +K
Sbjct: 1726 EDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKK 1777
Score = 38.9 bits (89), Expect = 0.022
Identities = 51/231 (22%), Positives = 101/231 (43%), Gaps = 33/231 (14%)
Query: 169 KGGSIDFSFSGIIPQGNEDNDDKGDTESVVSESRVPVG--KYHVKESFASILESILDKYG 226
K G+++ F I + + + DD +ESR+ K + ++ FA + + +
Sbjct: 1526 KSGTVNVEF---IRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQR 1582
Query: 227 DIGASCHLESLVLRSYYIECVCFVVQELQSDSIMHLTKSKINELVAILKDVESAQLRVAW 286
++ L+ L S I+ + E +S + +K K+ + +A + E +
Sbjct: 1583 EVVTIDRLKKK-LESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSK--- 1638
Query: 287 LRSALDEIAENVEVINQHQEVDAAKANTDRE-----------------MESLREQLESEM 329
+A +EI + V QEVD +A D E ++ ++EQLE E+
Sbjct: 1639 --AADEEIRKQV-----WQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEI 1691
Query: 330 ESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
+ + + ++ + E+ D+L+E E +ELE S +EVE++ +K
Sbjct: 1692 LAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKK 1742
Score = 33.9 bits (76), Expect = 0.72
Identities = 34/129 (26%), Positives = 65/129 (50%), Gaps = 23/129 (17%)
Query: 263 TKSKINELVAILKDVESAQ-LRVAWLRSALDEIAENVEVINQH-QEVDAAKANTDREMES 320
TKS++++ K+V S Q +++ L L E+ +E ++ AK + +ES
Sbjct: 1435 TKSELDDA----KNVSSEQYVQIKRLNEELSELRSVLEEADERCNSAIKAKKTAESALES 1490
Query: 321 LREQLESEMESLAEKEQEVADIKKRIPEISDRLKELELKSAELEQSM--LSSKSEVENLH 378
L++++++ + A+ E+ + KELE++ AELE+S+ S VE +
Sbjct: 1491 LKDEIDAANNAKAKAER--------------KSKELEVRVAELEESLEDKSGTVNVEFIR 1536
Query: 379 RKSL-IDEL 386
+K ID+L
Sbjct: 1537 KKDAEIDDL 1545
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/140 (21%), Positives = 68/140 (48%), Gaps = 29/140 (20%)
Query: 253 ELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDA--- 309
+++ +S M +++I+EL + + +E ++S L+ EV E++A
Sbjct: 1145 KVKQESDMEALRNQISELQSTIAKLEK-------IKSTLEG-----EVARLQGELEAEQL 1192
Query: 310 AKANTDREMESLREQLESEMESLAEK--------------EQEVADIKKRIPEISDRLKE 355
AK+N +++ + + LE + LAE+ EQE+++++ ++ E +++
Sbjct: 1193 AKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVN 1252
Query: 356 LELKSAELEQSMLSSKSEVE 375
+ + LE S + K E+E
Sbjct: 1253 SDSTNKHLETSFNNLKLELE 1272
Score = 32.0 bits (71), Expect = 2.7
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 7/91 (7%)
Query: 281 QLRVAWLRSALDE---IAENVEVINQHQEVDAAKANTDREMESLREQLESEMESLAEK-E 336
++RV + S LDE EN++ NQ + V+ + + E++ ++L + +E L +K E
Sbjct: 897 EIRVEDMESELDEKKLALENLQ--NQKRSVEEKVRDLEEELQE-EQKLRNTLEKLKKKYE 953
Query: 337 QEVADIKKRIPEISDRLKELELKSAELEQSM 367
+E+ ++K+ SD + LE EL++ +
Sbjct: 954 EELEEMKRVNDGQSDTISRLEKIKDELQKEV 984
Score = 31.2 bits (69), Expect = 4.7
Identities = 32/120 (26%), Positives = 58/120 (47%), Gaps = 15/120 (12%)
Query: 266 KINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAA---KANTDREMESLR 322
K N V +VE ++ L S L +A N E+ + + DA K D +E ++
Sbjct: 1074 KFNSEVTARSNVEKSKKT---LESQL--VAVNNELDEEKKNRDALEKKKKALDAMLEEMK 1128
Query: 323 EQLES---EMESL----AEKEQEVADIKKRIPEISDRLKELELKSAELEQSMLSSKSEVE 375
+QLES E +SL ++E ++ ++ +I E+ + +LE + LE + + E+E
Sbjct: 1129 DQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELE 1188
Score = 30.8 bits (68), Expect = 6.1
Identities = 32/143 (22%), Positives = 68/143 (47%), Gaps = 23/143 (16%)
Query: 260 MHLTKSKINELVAILKDVES-------AQLRVAWLRSALDEIAENV-----EVINQHQEV 307
++ ++ KI LVA + +V+ A+ ++ + AL+ E V E + E+
Sbjct: 1666 LNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSEL 1725
Query: 308 DAAKANTDREMESLREQLESEME---SLAEKEQEVAD----IKKRIPEISDRLKELELKS 360
+ +K E+E ++++ ++E+E L E ++++ D +KK++ + +L E E
Sbjct: 1726 EDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAK 1785
Query: 361 AELEQS----MLSSKSEVENLHR 379
LE + +EV+N R
Sbjct: 1786 KRLESENEDFLAKLDAEVKNRSR 1808
Score = 30.4 bits (67), Expect = 8.0
Identities = 26/143 (18%), Positives = 66/143 (45%), Gaps = 20/143 (13%)
Query: 253 ELQSDSIMHLTKSKINELVAILKDVESAQL-RVAWLRSALDEIAENVE------------ 299
EL+++ + K + V + + +SAQL + ALD++ + +E
Sbjct: 1186 ELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSE 1245
Query: 300 VINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRLKEL--- 356
N++ D+ + + +L+ +LE+E ++ E++ ++ + ++++L+E
Sbjct: 1246 ANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQ 1305
Query: 357 ----ELKSAELEQSMLSSKSEVE 375
E + +LE+ + K ++E
Sbjct: 1306 KESNEKRKVDLEKEVSELKDQIE 1328
Score = 30.4 bits (67), Expect = 8.0
Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 12/133 (9%)
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAA 310
+ EL+S+ T+ ++L LKD ES V L+ L E ++ + + DA
Sbjct: 837 ILELKSNLTDSTTQK--DKLEKSLKDTES---NVLDLQRQLKAEKETLKAM--YDSKDAL 889
Query: 311 KANTDREMESLREQLESEME----SLAEKEQEVADIKKRIPEISDRLKELELKSAELEQS 366
+A RE+E E +ESE++ +L + + +++++ ++ + L+E + LE+
Sbjct: 890 EAQK-RELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKL 948
Query: 367 MLSSKSEVENLHR 379
+ E+E + R
Sbjct: 949 KKKYEEELEEMKR 961
>MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 43.5 bits (101), Expect = 0.001
Identities = 34/144 (23%), Positives = 65/144 (44%), Gaps = 17/144 (11%)
Query: 251 VQELQS------------DSIMHLTKSKINELVAILKDVESAQLR----VAWLRSALDEI 294
VQELQS + +H ++++ + +L + E ++ VA L S L +
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 295 AENV-EVINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIKKRIPEISDRL 353
E + E Q V + E SL++QL+ EME+ E+ ++ + ++ + +L
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 354 KELELKSAELEQSMLSSKSEVENL 377
++ LE+ + E+ENL
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENL 1404
Score = 40.0 bits (92), Expect = 0.010
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 14/136 (10%)
Query: 254 LQSDSIMHLTKSKINELVAILK-----DVESAQLRVAWLRSALDEIAENVEVINQHQEVD 308
L S + ++K + V +LK + S + +V +R + E E+ Q ++
Sbjct: 1159 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE--ELTEQLEQFK 1216
Query: 309 AAKANTDREMESLREQ---LESEMESLAEKEQEVADIKKR----IPEISDRLKELELKSA 361
AKAN D+ ++L ++ L E+ L + +QEV KK+ + E+ + + E A
Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276
Query: 362 ELEQSMLSSKSEVENL 377
EL + ++EVE++
Sbjct: 1277 ELNDKVHKLQNEVESV 1292
Score = 37.0 bits (84), Expect = 0.085
Identities = 29/125 (23%), Positives = 60/125 (47%), Gaps = 17/125 (13%)
Query: 265 SKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQ 324
+K+ L+ + + E Q + L+ + + N+ +E++ + E L+EQ
Sbjct: 839 TKVKPLLQVTRQEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQ 895
Query: 325 LESEME----------SLAEKEQEVADI----KKRIPEISDRLKELELKSAELEQSMLSS 370
L++E E LA K+QE+ +I + R+ E DR ++L+ + ++ Q ML
Sbjct: 896 LQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 371 KSEVE 375
+ ++E
Sbjct: 956 EEQLE 960
Score = 34.7 bits (78), Expect = 0.42
Identities = 33/152 (21%), Positives = 69/152 (44%), Gaps = 29/152 (19%)
Query: 253 ELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEI----------AENVEV-I 301
ELQ+DS + + I +L + ++ Q + R++ DEI A+++E +
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
Query: 302 NQHQE----VDAAKANTDREMESLREQLESEMES--------------LAEKEQEVADIK 343
Q QE + A+ D E E L E+L S + +A+ E+E+ + +
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 344 KRIPEISDRLKELELKSAELEQSMLSSKSEVE 375
+ +SDR+++ ++ +L + + +S +
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
Score = 32.0 bits (71), Expect = 2.7
Identities = 25/97 (25%), Positives = 43/97 (43%), Gaps = 5/97 (5%)
Query: 284 VAWLRSALDEIAENVEVINQHQEVDAAKANTDREMESLREQLESEMESLAEKEQEVADIK 343
V L+ ALDE + E Q A+A +E L EQLE + A ++ ++
Sbjct: 1176 VTVLKKALDEETRSHEAQVQEMRQKHAQA-----VEELTEQLEQFKRAKANLDKNKQTLE 1230
Query: 344 KRIPEISDRLKELELKSAELEQSMLSSKSEVENLHRK 380
K +++ L+ L E+E +++V+ L K
Sbjct: 1231 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1267
Score = 31.6 bits (70), Expect = 3.6
Identities = 31/148 (20%), Positives = 66/148 (43%), Gaps = 25/148 (16%)
Query: 252 QELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQHQEVDAAK 311
QEL+ I+H ++++ E + +++ + ++A L+E E E Q +++
Sbjct: 918 QELEE--ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 975
Query: 312 ANT-------------------DREMESLREQLESEMESLAEKEQEVADIKKRIPEISDR 352
A +E + L E++ +LAE+E++ ++ K +
Sbjct: 976 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1035
Query: 353 LKELELKSAELEQSMLSSKSEVENLHRK 380
+ ELE++ + E+ S+ E+E L RK
Sbjct: 1036 ISELEVRLKKEEK----SRQELEKLKRK 1059
Score = 31.6 bits (70), Expect = 3.6
Identities = 39/195 (20%), Positives = 84/195 (43%), Gaps = 23/195 (11%)
Query: 191 KGDTESVVSESRVPVGKYHVKESFASILESILDKYGDIGASCHLESLVLRSYYIECVCFV 250
K ES++SE V + K +E LE + K + H + L++ E
Sbjct: 1029 KNKHESMISELEVRLKK---EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE---LK 1082
Query: 251 VQELQSDSIMHLTKSKINELVAILKDVESAQLRVAWLRSALDEIAENVEVINQ-HQEVDA 309
+Q + + + +++++ +A +A ++ L + ++ E+++ + +
Sbjct: 1083 MQLAKKEEELQAALARLDDEIA---QKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Query: 310 AKANTDREMESLREQLESEMESLA-------EKEQEVADIKKRIPEISDRLKELELKSAE 362
K + E+E+L+ +LE ++S A ++EQEV +KK + E E A+
Sbjct: 1140 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE------ETRSHEAQ 1193
Query: 363 LEQSMLSSKSEVENL 377
+++ VE L
Sbjct: 1194 VQEMRQKHAQAVEEL 1208
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.308 0.126 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,840,987
Number of Sequences: 164201
Number of extensions: 1952030
Number of successful extensions: 13043
Number of sequences better than 10.0: 882
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 662
Number of HSP's that attempted gapping in prelim test: 10011
Number of HSP's gapped (non-prelim): 3033
length of query: 387
length of database: 59,974,054
effective HSP length: 112
effective length of query: 275
effective length of database: 41,583,542
effective search space: 11435474050
effective search space used: 11435474050
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Lotus: description of TM0017.9