BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0012c.1
(943 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
WDR3_HUMAN (Q9UNX4) WD-repeat protein 3 686 0.0
YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in ch... 563 e-160
DIP2_YEAST (Q12220) DOM34 interacting protein 2 540 e-153
YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466 214 1e-54
YL24_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124 176 2e-43
YS00_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800 173 2e-42
HET1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1 154 8e-37
TUP1_CANAL (P56093) Transcriptional repressor TUP1 125 5e-28
TU12_SCHPO (Q9UUG8) Transcriptional repressor tup12 121 8e-27
RCO1_NEUCR (P78706) Transcriptional repressor rco-1 113 3e-24
WDS_DROME (Q9V3J8) Will die slowly protein 112 6e-24
KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.1.129) (... 109 3e-23
TU11_SCHPO (Q09715) Transcriptional repressor tup11 107 1e-22
TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (... 107 1e-22
TUP1_KLULA (P56094) Transcriptional repressor TUP1 102 4e-21
LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB ... 102 4e-21
LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase I... 102 4e-21
LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase I... 102 4e-21
LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase I... 102 4e-21
LI23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cel... 100 3e-20
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3
Length = 943
Score = 686 bits (1770), Expect = 0.0
Identities = 375/961 (39%), Positives = 561/961 (58%), Gaps = 68/961 (7%)
Query: 1 MVKAYLRYEPAAAFGVIASVDSNITY----DSSGKHLLSPALEKIAVWHVRQGICTKTLT 56
+ K YLRY +A FGVI S NI + G+++ PA E + +W +R+G L
Sbjct: 3 LTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILIL- 61
Query: 57 PPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYN 116
+G VT + +P +A GY DGSIRI G T NGHK A+T L+Y+
Sbjct: 62 -----QGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYD 116
Query: 117 QAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVW 176
Q G LASGSKD D+I+WDV+ E+GL+RL+GH+D +T +FL LV+S KD ++ W
Sbjct: 117 QLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWW 176
Query: 177 DLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKH-------DSVDGAS 229
DLDTQHC + + GH +E+W + + E+ L+TG++D ELR + I + + D
Sbjct: 177 DLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKK 236
Query: 230 VNGGD----------------DSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSGNLLAC 273
+ G D + + R G I R+ +DRV + +K+G +LAC
Sbjct: 237 IKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILAC 296
Query: 274 QVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTH 333
+E++ +L E ++K +++ KK +K K H++ +ED
Sbjct: 297 HGTDSVLELFCILSKKEIQKKMDKKM--KKARKKAKL--------HSSKGEEEDPEV--- 343
Query: 334 GTIETSNPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQ 393
N +++ D + + I+ S KI S S P L + L L NNL+E YS+
Sbjct: 344 ------NVEMSLQDEIQRVTNIKTSAKIKSFDLIHS-PHGELKAVFL-LQNNLVELYSLN 395
Query: 394 SS----ETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSG 449
S + +T I + GHRSDVR+++ SSDN +LS + +++KIWN +T C+RT+
Sbjct: 396 PSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCE 455
Query: 450 YGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGS 509
Y LCS +P ++ ++GTK G +++ D+ SG LE I+AH G+L S++ PD+ FVTG
Sbjct: 456 YALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGG 515
Query: 510 ADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKV 569
AD VKFW++++ + K+L+V RT+++++DVL V+ SP+ K +AV+LLD TVK+
Sbjct: 516 ADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKI 575
Query: 570 HFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDS 629
+VDT KFFLSLYGHKLPV+CMDIS DG LI TGSAD+N+KIWGLDFGDCHKSLFAHDDS
Sbjct: 576 FYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDS 635
Query: 630 VMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSH 689
VM ++FVPK+H F+ GKD ++ WDADKFE + TLEGHH +IWCLA+S GD++V+ SH
Sbjct: 636 VMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSH 695
Query: 690 DRSIRRWDRTEEQFFLEEEKEKRLEEKFEADLDYTSENKYAPKEEIPEEGAVALAGKKTE 749
D+S+R W+RT E LEEE+E E ++E + E++ A E +G GKKT
Sbjct: 696 DKSLRLWERTREPLILEEEREMEREAEYEESV--AKEDQPAVPGE--TQGDSYFTGKKTI 751
Query: 750 ETLTATDLIIERLDIAEAEDKRIAEHQEE-KNNINIAAFQANPLM---NGLSPSDYVLSA 805
ET+ A + I+E +++ E ++ EH+ K +NP++ +SPS YVL
Sbjct: 752 ETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEI 811
Query: 806 FSNVHSNDLEQTLMALPFSDALKLISYLKEWTSYSDKVELVCRIGILLVQTHHNQLFATP 865
F + S++LE++L+ LPFS ++ E+ VEL+CR L++ H Q+ +
Sbjct: 812 FKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQ 871
Query: 866 AAIPLLTALRE--YQCVKEWKDKCGYNLAAMYHMQQMMASNSEAPFHNARSMLLEAKQSK 923
+P++ LRE V + +D G+N+A + ++++ + SE F + LE K+ K
Sbjct: 872 MLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRK 931
Query: 924 R 924
R
Sbjct: 932 R 932
>YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in
chromosome II
Length = 922
Score = 563 bits (1452), Expect = e-160
Identities = 343/976 (35%), Positives = 512/976 (52%), Gaps = 110/976 (11%)
Query: 1 MVKAYLRYEPAAAFGVIASVDSNITYDSSGK-----HLLSPALEKIAVWHVRQGICTKTL 55
MVK+Y RYEP FGVIAS NI S + LE + W ++ G L
Sbjct: 1 MVKSYTRYEPTEFFGVIASSGCNILGQPSSSAKSVGRAIVGGLESVLEWDLKTG----QL 56
Query: 56 TPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRY 115
S VT IA+ + A GY DGSIR+ G TLNGHK AVT + +
Sbjct: 57 LSKWKDSDCSAKVTCIANF--DEMYAVGYADGSIRLWKD--GELLITLNGHKSAVTTMDF 112
Query: 116 NQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFL----------------- 158
++ G+ LASGS D D+I+WD+V ETGLFRLRGH+DQ+T ++F+
Sbjct: 113 DKMGTRLASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPPSKNTAEETVVDTDI 172
Query: 159 ----------SSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVT 208
SS L+S KD F+++WDL QHC++ H EIW++ V P + +T
Sbjct: 173 DSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEIWAMCVSPDAKRCLT 232
Query: 209 GSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSG 268
+++ + I DD++ + + G RQS+DR T+ ++ S
Sbjct: 233 AGTGSDVKVWEISFP----------DDNNFTPTTKAFQQLGTFTRQSRDRPITLAYDVSN 282
Query: 269 NLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDN 328
+ Q + +E++R+ +E ++ RR RKK +
Sbjct: 283 RYVVFQAHDRLLEVFRLRSSAELEKILNRRRRRKKSE----------------------- 319
Query: 329 STVTHGTIETSNPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAGLALSLNNNLLE 388
+ +IT+ D ++ IR + + S+++ P N L SL NN +E
Sbjct: 320 -----------DVSITLKDEYEPFALIRTTARASSVAWIPG---NRTPTLVTSLQNNSIE 365
Query: 389 FYSIQ----------SSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPT 438
Y++ + ++ AI++ GHR+DVR++ LS+++ +LS ++ ++K+WN
Sbjct: 366 VYALDVKSEGSAAPLTERASRISAIEIPGHRADVRTLALSANHDVILSGANGSLKLWNKK 425
Query: 439 TGSCLRTIDSGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAA 498
T SC+RTI+ GY L + + +K + K G +E+ DI S + +E I+AH G++ +A
Sbjct: 426 TTSCIRTIECGYVLAASFINNDKCIVSAYKSGELEVYDIASSSLIERIQAHDGAIWDLAV 485
Query: 499 LPDKNSFVTGSADHDVKFWEYQIKQK--PGQATK--QLAVSNVRTMKMNDDVLVVAISPD 554
D F T SADH VK W + PG K L + R + DDVL V ISPD
Sbjct: 486 GHDGTYFATASADHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQIDFTDDVLAVKISPD 545
Query: 555 AKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGL 614
+++A +LLD+TVKV+++D+ KFFL+LYGHKLPVL MDIS D L+VT SADKN+KIWGL
Sbjct: 546 GRFVAASLLDNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGL 605
Query: 615 DFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWC 674
DFGDCHKS+FAH DS+M V F P T+ F+ KDR V YWD F+ +L L GHH+++W
Sbjct: 606 DFGDCHKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWA 665
Query: 675 LAISNRGDFIVTGSHDRSIRRWDRTEEQFFLEEEKEKRLEEKFEADLDYTSENKYAPKEE 734
LA+ F+V+GSHD SIR W++ ++ FLEEE+E+ LEE++E+ L + EN A E
Sbjct: 666 LAVG--PTFVVSGSHDHSIRLWEQGDDLVFLEEERERELEEQYESTLVSSYENAEADGE- 722
Query: 735 IPEEGAVALAGKKTEETLTATDLIIERLDIA-EAEDKRIAEHQEEKNNINIAAFQANPLM 793
++G VA K+T E+L + I+E + I E D+ I + + A NP++
Sbjct: 723 -VKDGDVAAVTKQTIESLKDGEKILEAITIGIEDLDQEIQYRLDLLKSPGKARGPRNPIL 781
Query: 794 N--GLSPSDYVLSAFSNVHSNDLEQTLMALPFSDALKLISYLKEWTSYSDKVELVCRIGI 851
G+S +YVL+ F + S+ L+ L+ LPF L L ++ W S + LV RI
Sbjct: 782 AHLGVSAEEYVLNTFKKIRSSHLDDALLVLPFEHVLSLFRFIDIWASRKWSIPLVSRIIF 841
Query: 852 LLVQTHHNQLFATPAAIPLLTALRE--YQCVKEWKDKCGYNLAAMYHMQQMMASNSEAPF 909
L++T+H QL T PLL +R ++E + GYN A + +++
Sbjct: 842 FLLRTYHRQLTTTVKMRPLLNNIRSSLRGSLQEERSLIGYNAAGLSYLRHEWELTHNTSL 901
Query: 910 HNARSMLLEAKQSKRS 925
+ S LE KR+
Sbjct: 902 EDIDSTSLEVDGKKRA 917
>DIP2_YEAST (Q12220) DOM34 interacting protein 2
Length = 943
Score = 540 bits (1390), Expect = e-153
Identities = 341/958 (35%), Positives = 522/958 (53%), Gaps = 107/958 (11%)
Query: 1 MVKAYLRYEPAAAFGVIAS--------VDSNITYDSSGKHLLSPALEKIAVWHVRQGICT 52
MVK+Y R+E AAAFGVIAS S + S L++ ALE + +W ++ G
Sbjct: 1 MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLV 60
Query: 53 KTLT---PPPPS--RGPSPA-VTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGH 106
L+ PP S RG PA T + + + L+A GY DG I++ D T NGH
Sbjct: 61 SKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGH 120
Query: 107 KGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKK-LV 165
K A+T L+++ G+ L SGSKD+++I+WD+VGE GL++LR H+D +T F G+ L+
Sbjct: 121 KAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITG--FWCQGEDWLI 178
Query: 166 SSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY--GIKHD 223
S+SKD +++WDL T C++ H E W + V + L+T D +++ + I++D
Sbjct: 179 STSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVK--DDLLITTGTDSQVKIWKLDIEND 236
Query: 224 SVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQF----NKSGNLLACQVAGKT 279
+ G L G ++QSK R ++F + + Q A KT
Sbjct: 237 KMGGK----------------LTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKT 280
Query: 280 VEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETS 339
+E +R+ + E R K+R R KEK +E + + KE S+
Sbjct: 281 IETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSI--------KESYSSF-------- 324
Query: 340 NPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETN- 398
+ TIR+ KI S S+ +T +S L L+ ++N +E+YSI + +
Sbjct: 325 --------ILHPFQTIRSLYKIKSASW--TTVSSSKLELVLTTSSNTIEYYSIPYEKRDP 374
Query: 399 ------KTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGL 452
KT I+LQG R+DVRS+ +S DN L + S+ ++KIWN T C+RT + GY L
Sbjct: 375 TSPAPLKTHTIELQGQRTDVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYAL 434
Query: 453 CSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIE-AHGGSLRSIAALPDKNSFVTGSAD 511
LP ++GT++G +++ D+ S + L+ IE AH ++ S+ D VTGSAD
Sbjct: 435 TCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSAD 494
Query: 512 HDVKFWEYQIKQK--PGQATKQLAVSNVR---TMKMNDDVLVVAISPDAKYIAVALLDST 566
VKFW+++++ PG K L V + T+++ DD+L V +SPD +Y+A++LLD+T
Sbjct: 495 KTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNT 554
Query: 567 VKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAH 626
VKV F+D+ KF+LSLYGHKLPVL +DIS D +I+T SADKN+KIWGLDFGDCHKSLFAH
Sbjct: 555 VKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAH 614
Query: 627 DDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVT 686
DS+M VKF+P++H FS KD V YWD +KFE + L H +++W LA++ G F+V+
Sbjct: 615 QDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVS 674
Query: 687 GSHDRSIRRWDRTEEQFFLEEEKEKRLEEKFEADLDYTSE---NKYAPKEEIPEEGAVAL 743
SHD SIR W+ TE+Q FLEEEKEK LEE++E L + E A K + EG
Sbjct: 675 SSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDE 734
Query: 744 AG---KKTEETLTATDLIIERLDIAEAEDKRIAEHQE-----EKNNINIAAF--QANPLM 793
A K+T E+L A + ++E LD+ AE + + + ++ + A Q N ++
Sbjct: 735 ASGVHKQTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVL 794
Query: 794 NGL--SPSDYVLSAFSNVHSNDLEQTLMALPFSDALKLISY----LKEWTSYSDKVELVC 847
+ +P Y++ + + LE LM +PFS LK + + ++ T + L+C
Sbjct: 795 IAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLIC 854
Query: 848 RIGILLVQTHHNQLFATPAAIPLL------TALREYQCVKEWKDKCGYNLAAMYHMQQ 899
+ +++ +H +L + L T LR +K +D G+N+ + ++Q
Sbjct: 855 KNLFFIIKFNHKELVSQKNEELKLQINRVKTELR--SALKSTEDDLGFNVQGLKFVKQ 910
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466
Length = 1526
Score = 214 bits (544), Expect = 1e-54
Identities = 179/657 (27%), Positives = 289/657 (43%), Gaps = 68/657 (10%)
Query: 67 AVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGS 126
+V ++A +P L A G G +R ++ G T GH V ++ ++Q G +LASGS
Sbjct: 866 SVLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGS 925
Query: 127 KDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQI 186
D V LWD+ L +GH +V VVF + L S S D+ +R+WD+ + C+ I
Sbjct: 926 DDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYI 985
Query: 187 VSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHD------------------SVDGA 228
GH ++SV + L TGS D+ +R + I S DGA
Sbjct: 986 FQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFSSDGA 1045
Query: 229 SVNGGDDSSVSSKWDVL--RLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVL 286
+ G D WD+ +Q + V +V F+ G +LA +G +I R+
Sbjct: 1046 MLASGSDDQTVRLWDISSGNCLYTLQGHTSC-VRSVVFSPDGAMLA---SGGDDQIVRLW 1101
Query: 287 DDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVP 346
D S ++ + L + NG T+ +G+ S+ + +
Sbjct: 1102 DISSGNC-----LYTLQGYTSWVRFLVFSPNG----------VTLANGS---SDQIVRLW 1143
Query: 347 DVF--KLLHTIRASKK-ICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAI 403
D+ K L+T++ + +++F P A LA + + + I SS K L I
Sbjct: 1144 DISSKKCLYTLQGHTNWVNAVAFSPDG-----ATLASGSGDQTVRLWDISSS---KCLYI 1195
Query: 404 DLQGHRSDVRSVTLSSDNSFLLS-TSHNAVKIWNPTTGSCLRTIDSGYGLCSLVL--PTN 460
LQGH S V SV + D S L S +S V++W + CL T + V+ P
Sbjct: 1196 -LQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVVFNPDG 1254
Query: 461 KYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQ 520
G+ D T+ + DI S CL + H + S+A PD + +GS D V+ WE
Sbjct: 1255 SMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEIS 1314
Query: 521 IKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLS 580
++K L T ++ V SPD +A D TV++ + + + +
Sbjct: 1315 -------SSKCLHTFQGHTSWVSS----VTFSPDGTMLASGSDDQTVRLWSISSGECLYT 1363
Query: 581 LYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTH 640
GH V + S DG ++ +GS D+ +++W + G C +L H++ V ++ F P
Sbjct: 1364 FLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGT 1423
Query: 641 YVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D+ V W+ E L TL GH + +A S+ G + +GS D +I+ WD
Sbjct: 1424 LLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWD 1480
Score = 199 bits (505), Expect = 4e-50
Identities = 172/659 (26%), Positives = 281/659 (42%), Gaps = 91/659 (13%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
+++ + GK L S + ++ + +W + G C KT +G + V S+ +P+S ++
Sbjct: 910 NSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTF------KGHTSRVRSVVFSPNSLML 963
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGET 140
A+G D ++R+ D G C GH G V ++ +N GS+LA+GS D V LWD+
Sbjct: 964 ASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQ 1023
Query: 141 GLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVD 200
+ +GH V VVF S G L S S D+ +R+WD+ + +C+ + GH S + SV
Sbjct: 1024 CFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFS 1083
Query: 201 PGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVA 260
P DGA + G D + WD+ G + +
Sbjct: 1084 P------------------------DGAMLASGGDDQIVRLWDISS--GNCLYTLQGYTS 1117
Query: 261 TVQF---NKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATEN 317
V+F + +G LA G + +I R+ D S K T
Sbjct: 1118 WVRFLVFSPNGVTLA---NGSSDQIVRLWDISSKK-------------------CLYTLQ 1155
Query: 318 GHNNNEN----KEDNSTVTHGTIETSNPTITVPDVF--KLLHTIRASKK-ICSISFCPST 370
GH N N D +T+ G+ + T+ + D+ K L+ ++ + S+ F P
Sbjct: 1156 GHTNWVNAVAFSPDGATLASGS---GDQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDG 1212
Query: 371 PKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLS-TSH 429
+ LA ++ + + I SS+ T QGH S V SV + D S L S +S
Sbjct: 1213 -----STLASGSSDQTVRLWEINSSKCLCTF----QGHTSWVNSVVFNPDGSMLASGSSD 1263
Query: 430 NAVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNKYGLVGTKDGTIEIIDIGSGTCLEAIE 487
V++W+ ++ CL T + V P G+ D T+ + +I S CL +
Sbjct: 1264 KTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQ 1323
Query: 488 AHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVL 547
H + S+ PD +GS D V+ W G+ + + V
Sbjct: 1324 GHTSWVSSVTFSPDGTMLASGSDDQTVRLWSIS----SGECLYTF-------LGHTNWVG 1372
Query: 548 VVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADK 607
V SPD +A D TV++ + + K +L GH V + S DG L+ +GS D+
Sbjct: 1373 SVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQ 1432
Query: 608 NLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLE 666
+++W + G+C +L H +SV +V F + S D + WD E + TL+
Sbjct: 1433 TVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVKTGECIKTLK 1491
Score = 171 bits (433), Expect = 8e-42
Identities = 151/644 (23%), Positives = 270/644 (41%), Gaps = 65/644 (10%)
Query: 79 LIAAGYGDGSIRILD-SDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVV 137
+I A + + S+R ++ ++ + G+V + ++ G + A+G V W+
Sbjct: 835 IIGADFTNTSLRCVNFTEANLAYSVFTKILGSVLTVAFSPDGKLFATGDSGGIVRFWEAA 894
Query: 138 GETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSV 197
L +GH V V F GK L S S D+ +R+WD+ + C++ GH S + SV
Sbjct: 895 TGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSV 954
Query: 198 DVDPGERYLVTGSADKELRFYGIKHD------------------SVDGASVNGGDDSSVS 239
P L +GS+D+ +R + I ++DG+ + G
Sbjct: 955 VFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTV 1014
Query: 240 SKWDV--LRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKR 297
WD+ + F Q + V +V F+ G +LA +G + R+ D S
Sbjct: 1015 RLWDISSSQCFYIFQGHT-SCVRSVVFSSDGAMLA---SGSDDQTVRLWDISSGNCLYTL 1070
Query: 298 RVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRA 357
+ H + P A + D+ V I + N L+T++
Sbjct: 1071 QGHTSCVRSVVFSPDGAM------LASGGDDQIVRLWDISSGN----------CLYTLQG 1114
Query: 358 -SKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVT 416
+ + + F P+ LA ++ ++ + I S K LQGH + V +V
Sbjct: 1115 YTSWVRFLVFSPNG-----VTLANGSSDQIVRLWDISS----KKCLYTLQGHTNWVNAVA 1165
Query: 417 LSSDNSFLLSTS-HNAVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNKYGLVGTKDGTIE 473
S D + L S S V++W+ ++ CL + + V+ P G+ D T+
Sbjct: 1166 FSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVR 1225
Query: 474 IIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLA 533
+ +I S CL + H + S+ PD + +GS+D V+ W+ ++K L
Sbjct: 1226 LWEINSSKCLCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDI-------SSSKCLH 1278
Query: 534 VSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDI 593
T +N VA +PD +A D TV++ + + K + GH V +
Sbjct: 1279 TFQGHTNWVNS----VAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTF 1334
Query: 594 SSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNY 653
S DG ++ +GS D+ +++W + G+C + H + V +V F P + S D+ V
Sbjct: 1335 SPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRL 1394
Query: 654 WDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
W + L TL+GH+ + + S G + +GS D+++R W+
Sbjct: 1395 WSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWN 1438
Score = 167 bits (422), Expect = 2e-40
Identities = 142/521 (27%), Positives = 232/521 (44%), Gaps = 78/521 (14%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + S G L S + ++ + +W + G C TL +G + V S+ +P +++A
Sbjct: 1037 SVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTL------QGHTSCVRSVVFSPDGAMLA 1090
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+G D +R+ D G C TL G+ V L ++ G LA+GS D V LWD+ +
Sbjct: 1091 SGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKC 1150
Query: 142 LFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDP 201
L+ L+GH + V V F G L S S D+ +R+WD+ + C+ I+ GH S + SV +P
Sbjct: 1151 LYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFNP 1210
Query: 202 GERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVAT 261
L +GS+D+ +R + I +S G S V+S
Sbjct: 1211 DGSTLASGSSDQTVRLWEI--NSSKCLCTFQGHTSWVNS--------------------- 1247
Query: 262 VQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNN 321
V FN G++LA + KTV ++ + + + +H T GH N
Sbjct: 1248 VVFNPDGSMLASGSSDKTVRLWDI--------SSSKCLH--------------TFQGHTN 1285
Query: 322 NEN----KEDNSTVTHGTIETSNPTITVPDV--FKLLHTIRA-SKKICSISFCPSTPKNS 374
N D S + G + + T+ + ++ K LHT + + + S++F P
Sbjct: 1286 WVNSVAFNPDGSMLASG---SGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTM-- 1340
Query: 375 LAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTS-HNAVK 433
LA ++ + +SI S E T GH + V SV S D + L S S V+
Sbjct: 1341 ---LASGSDDQTVRLWSISSGECLYTFL----GHTNWVGSVIFSPDGAILASGSGDQTVR 1393
Query: 434 IWNPTTGSCLRTIDSGYGLCSLVL--PTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGG 491
+W+ ++G CL T+ ++ P G+ D T+ + +I SG CL + H
Sbjct: 1394 LWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHIN 1453
Query: 492 SLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQL 532
S+RS+A D +GS D +K W+ K G+ K L
Sbjct: 1454 SVRSVAFSSDGLILASGSDDETIKLWDV----KTGECIKTL 1490
Score = 94.0 bits (232), Expect = 2e-18
Identities = 52/164 (31%), Positives = 79/164 (47%)
Query: 541 KMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLI 600
K+ VL VA SPD K A V+ T K L+ GH V + S DG ++
Sbjct: 862 KILGSVLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKML 921
Query: 601 VTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFE 660
+GS D+ +++W + G C K+ H V +V F P + + S D+ V WD E
Sbjct: 922 ASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGE 981
Query: 661 RLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWDRTEEQFF 704
L +GH ++ +A + G + TGS D+++R WD + Q F
Sbjct: 982 CLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCF 1025
Score = 79.7 bits (195), Expect = 3e-14
Identities = 51/207 (24%), Positives = 92/207 (43%), Gaps = 11/207 (5%)
Query: 491 GSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVA 550
GS+ ++A PD F TG + V+FWE K+L +N V
Sbjct: 865 GSVLTVAFSPDGKLFATGDSGGIVRFWE-------AATGKELLTCKGHNSWVNS----VG 913
Query: 551 ISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLK 610
S D K +A D TV++ + + + + GH V + S + ++ +GS+D+ ++
Sbjct: 914 FSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVR 973
Query: 611 IWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHA 670
+W + G+C H V +V F + + D+ V WD + +GH +
Sbjct: 974 LWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTS 1033
Query: 671 DIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ + S+ G + +GS D+++R WD
Sbjct: 1034 CVRSVVFSSDGAMLASGSDDQTVRLWD 1060
Score = 35.4 bits (80), Expect = 0.72
Identities = 23/86 (26%), Positives = 41/86 (46%), Gaps = 7/86 (8%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
+I + G L S + ++ + +W++ G C TL G +V S+A + ++A
Sbjct: 1415 SIVFSPDGTLLASGSDDQTVRLWNISSGECLYTL------HGHINSVRSVAFSSDGLILA 1468
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHK 107
+G D +I++ D G C TL K
Sbjct: 1469 SGSDDETIKLWDVKTGECIKTLKSEK 1494
>YL24_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124
Length = 1683
Score = 176 bits (447), Expect = 2e-43
Identities = 159/650 (24%), Positives = 266/650 (40%), Gaps = 83/650 (12%)
Query: 63 GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVL 122
G V SI+ + IA+G D +I++ D G TLNGH+ AV ++ ++ G +
Sbjct: 1070 GHKDGVISISISRDGQTIASGSLDKTIKLWSRD-GRLFRTLNGHEDAVYSVSFSPDGQTI 1128
Query: 123 ASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQH 182
ASG D + LW T L + GH V +V F GK L S+S D +++WD +
Sbjct: 1129 ASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQ 1188
Query: 183 CMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKW 242
+ ++GH + + +V P + + GS DK ++ + + D ++NG D W
Sbjct: 1189 LLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWH-RQDGKLLKTLNGHQD------W 1241
Query: 243 DVLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRK 302
V ++ F+ G LA A KT++++R+ D K
Sbjct: 1242 ----------------VNSLSFSPDGKTLASASADKTIKLWRIADGKLVK---------- 1275
Query: 303 KEKKHGKEPLEATENGHNNN--------ENKEDNSTVTHGTIETSNPTITVPDVFKLLHT 354
T GHN++ + K S TI+ N + F
Sbjct: 1276 ------------TLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGIELETFT---- 1319
Query: 355 IRASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRS 414
S + +++F P + N +A +L L + I E L G+ S V +
Sbjct: 1320 -GHSGGVYAVNFLPDS--NIIASASLDNTIRLWQRPLISPLEV-------LAGN-SGVYA 1368
Query: 415 VTLSSDNSFLLSTSHNA-VKIWNPTTGSCLRTIDSGYGLCSLVL-PTNKYGLVGTKDGTI 472
V+ D S + + + +++W+ GS L+T+ + + P D T+
Sbjct: 1369 VSFLHDGSIIATAGADGNIQLWHSQDGSLLKTLPGNKAIYGISFTPQGDLIASANADKTV 1428
Query: 473 EIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQL 532
+I + G L+ + H + + PD + + S D+ VK W G+ K L
Sbjct: 1429 KIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVS----DGKFKKTL 1484
Query: 533 AVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMD 592
D+V V+ SPD K IA A D T+++ + SL H V ++
Sbjct: 1485 KGHT-------DEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVN 1537
Query: 593 ISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVN 652
+ DG ++ + SADK +K+W G + H + V + F P Y+ S +D+ V
Sbjct: 1538 FNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVK 1597
Query: 653 YWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWDRTEEQ 702
W D L TL H A + S G +++GS D + + W +Q
Sbjct: 1598 IWQIDG-HLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWRFDSQQ 1646
Score = 165 bits (417), Expect = 6e-40
Identities = 154/602 (25%), Positives = 249/602 (40%), Gaps = 85/602 (14%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++++ G+ + S +K I +W G KT+T G V ++ +P +A
Sbjct: 1118 SVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTIT------GHEQTVNNVYFSPDGKNLA 1171
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+ D SI++ D+ G TL GH V +R++ G +A+GS+D V LW
Sbjct: 1172 SASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKL 1231
Query: 142 LFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDP 201
L L GH+D V + F GK L S+S DK +++W + ++ + GH+ +W V+
Sbjct: 1232 LKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSS 1291
Query: 202 GERYLVTGSADKELRF---YGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDR 258
+ + + S D ++ +GI+ ++ G S GG
Sbjct: 1292 DGKAIASASRDNTIKLWNRHGIELETFTGHS--GG------------------------- 1324
Query: 259 VATVQFNKSGNLLACQVAGKTVEIY-RVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATEN 317
V V F N++A T+ ++ R L V+ G A +
Sbjct: 1325 VYAVNFLPDSNIIASASLDNTIRLWQRPLISPLEVLAGNSGVYAVSFLHDGSIIATAGAD 1384
Query: 318 GHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAG 377
G+ + +D S LL T+ +K I ISF TP+ L
Sbjct: 1385 GNIQLWHSQDGS---------------------LLKTLPGNKAIYGISF---TPQGDL-- 1418
Query: 378 LALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSH-NAVKIWN 436
+A + + ++ + ++ + KTL GH ++V V S D L S S N VK+WN
Sbjct: 1419 IASANADKTVKIWRVRDGKALKTLI----GHDNEVNKVNFSPDGKTLASASRDNTVKLWN 1474
Query: 437 PTTGSCLRTIDSGYGLCSLV--LPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLR 494
+ G +T+ V P K + D TI + D SG ++++ AH +
Sbjct: 1475 VSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVY 1534
Query: 495 SIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLA-VSNVRTMKMNDDVLVVAISP 553
S+ PD + + SAD VK W + G + SNV V + SP
Sbjct: 1535 SVNFNPDGSMLASTSADKTVKLW----RSHDGHLLHTFSGHSNV--------VYSSSFSP 1582
Query: 554 DAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWG 613
D +YIA A D TVK+ +D +L H+ V+ S DG +++GS D KIW
Sbjct: 1583 DGRYIASASEDKTVKIWQIDG-HLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWR 1641
Query: 614 LD 615
D
Sbjct: 1642 FD 1643
Score = 149 bits (377), Expect = 3e-35
Identities = 138/580 (23%), Positives = 244/580 (41%), Gaps = 74/580 (12%)
Query: 144 RLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGE 203
RL GH+D V + G+ + S S DK +++W D + + ++GH ++SV P
Sbjct: 1067 RLEGHKDGVISISISRDGQTIASGSLDKTIKLWSRDGR-LFRTLNGHEDAVYSVSFSPDG 1125
Query: 204 RYLVTGSADKELRFYGIK------------------HDSVDGASVNGGDDSSVSSKWDVL 245
+ + +G +DK ++ + + S DG ++ WD
Sbjct: 1126 QTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTT 1185
Query: 246 --RLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKK 303
+L + S V TV+F+ G +A KTV+++ HR+
Sbjct: 1186 SGQLLMTLTGHSAG-VITVRFSPDGQTIAAGSEDKTVKLW----------------HRQD 1228
Query: 304 EKKHGKEPLEATENGH----NNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRA-S 358
K L T NGH N+ D T+ + + + + D KL+ T++ +
Sbjct: 1229 GK------LLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIAD-GKLVKTLKGHN 1281
Query: 359 KKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLS 418
+ ++F + +A + +N ++ ++ E GH V +V
Sbjct: 1282 DSVWDVNF-----SSDGKAIASASRDNTIKLWNRHGIELE-----TFTGHSGGVYAVNFL 1331
Query: 419 SDNSFLLSTS-HNAVKIWNPTTGSCLRTIDSGYGLCSL-VLPTNKYGLVGTKDGTIEIID 476
D++ + S S N +++W S L + G+ ++ L DG I++
Sbjct: 1332 PDSNIIASASLDNTIRLWQRPLISPLEVLAGNSGVYAVSFLHDGSIIATAGADGNIQLWH 1391
Query: 477 IGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSN 536
G+ L+ + + ++ I+ P + + +AD VK W + + G+A K L +
Sbjct: 1392 SQDGSLLKTLPGN-KAIYGISFTPQGDLIASANADKTVKIW----RVRDGKALKTLIGHD 1446
Query: 537 VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSD 596
K+N SPD K +A A D+TVK+ V KF +L GH V + S D
Sbjct: 1447 NEVNKVN-------FSPDGKTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPD 1499
Query: 597 GDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDA 656
G +I + SADK +++W G+ KSL AH+D V +V F P + S D+ V W +
Sbjct: 1500 GKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRS 1559
Query: 657 DKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRW 696
L T GH ++ + S G +I + S D++++ W
Sbjct: 1560 HDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIW 1599
Score = 139 bits (349), Expect = 5e-32
Identities = 140/544 (25%), Positives = 224/544 (40%), Gaps = 74/544 (13%)
Query: 22 SNITYDSSGKHLLSPALE-KIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
+N+ + GK+L S + + I +W G TLT G S V ++ +P I
Sbjct: 1159 NNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLT------GHSAGVITVRFSPDGQTI 1212
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGET 140
AAG D ++++ G TLNGH+ V +L ++ G LAS S D + LW +
Sbjct: 1213 AAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGK 1272
Query: 141 GLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQI--VSGHHSEIWSVD 198
+ L+GH D V DV F S GK + S+S+D +++W+ +H +++ +GH +++V+
Sbjct: 1273 LVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWN---RHGIELETFTGHSGGVYAVN 1329
Query: 199 VDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDS--SVSSKWD-----VLRLFGEI 251
P + + S D +R + + + V G+ +VS D G I
Sbjct: 1330 FLPDSNIIASASLDNTIRLW--QRPLISPLEVLAGNSGVYAVSFLHDGSIIATAGADGNI 1387
Query: 252 QR-QSKD-----------RVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRV 299
Q S+D + + F G+L+A A KTV+I+RV D K
Sbjct: 1388 QLWHSQDGSLLKTLPGNKAIYGISFTPQGDLIASANADKTVKIWRVRDGKALK------- 1440
Query: 300 HRKKEKKHGKEPLEATENGHNNNENK----EDNSTVTHGTIETSNPTITVPDVFKLLHTI 355
T GH+N NK D T+ + + + V D K T+
Sbjct: 1441 ---------------TLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDG-KFKKTL 1484
Query: 356 RA-SKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRS 414
+ + ++ +SF P +A + L + +S L L H V S
Sbjct: 1485 KGHTDEVFWVSFSPDG--KIIASASADKTIRLWDSFS-------GNLIKSLPAHNDLVYS 1535
Query: 415 VTLSSDNSFLLSTSHN-AVKIWNPTTGSCLRTID--SGYGLCSLVLPTNKYGLVGTKDGT 471
V + D S L STS + VK+W G L T S S P +Y ++D T
Sbjct: 1536 VNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKT 1595
Query: 472 IEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQ 531
++I I G L + H + S PD + ++GS D K W + +Q
Sbjct: 1596 VKIWQI-DGHLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWRFDSQQAKTSQMNT 1654
Query: 532 LAVS 535
L +S
Sbjct: 1655 LVMS 1658
Score = 122 bits (305), Expect = 6e-27
Identities = 123/518 (23%), Positives = 217/518 (41%), Gaps = 76/518 (14%)
Query: 187 VSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLR 246
+ GH + S+ + + + +GS DK ++ + S DG R
Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLW-----SRDG------------------R 1104
Query: 247 LFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKK 306
LF + +D V +V F+ G +A + KT+++++ D + K
Sbjct: 1105 LFRTLNGH-EDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTIT----------- 1152
Query: 307 HGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRA-SKKICSIS 365
G E + N + + + K S + +I+ + T +LL T+ S + ++
Sbjct: 1153 -GHE--QTVNNVYFSPDGKNLASASSDHSIKLWDTTSG-----QLLMTLTGHSAGVITVR 1204
Query: 366 FCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLL 425
F P +A + ++ + Q + KTL GH+ V S++ S D L
Sbjct: 1205 FSPDGQT-----IAAGSEDKTVKLWHRQDGKLLKTL----NGHQDWVNSLSFSPDGKTLA 1255
Query: 426 STSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVLPTN-----KYGLVGTKDGTIEIIDIGS 479
S S + +K+W G ++T+ G V N K ++D TI++ +
Sbjct: 1256 SASADKTIKLWRIADGKLVKTLK---GHNDSVWDVNFSSDGKAIASASRDNTIKLWN-RH 1311
Query: 480 GTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRT 539
G LE H G + ++ LPD N + S D+ ++ W Q+P +S +
Sbjct: 1312 GIELETFTGHSGGVYAVNFLPDSNIIASASLDNTIRLW-----QRP-------LISPLEV 1359
Query: 540 MKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDL 599
+ N V V+ D IA A D +++ +L G+K + + + GDL
Sbjct: 1360 LAGNSGVYAVSFLHDGSIIATAGADGNIQLWHSQDGSLLKTLPGNKA-IYGISFTPQGDL 1418
Query: 600 IVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKF 659
I + +ADK +KIW + G K+L HD+ V V F P + S +D V W+
Sbjct: 1419 IASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDG 1478
Query: 660 ERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ TL+GH +++ ++ S G I + S D++IR WD
Sbjct: 1479 KFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWD 1516
Score = 99.4 bits (246), Expect = 4e-20
Identities = 75/271 (27%), Positives = 118/271 (42%), Gaps = 28/271 (10%)
Query: 41 IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCE 100
I +WH + G KTL + A+ I+ TP LIA+ D +++I G
Sbjct: 1387 IQLWHSQDGSLLKTLPG-------NKAIYGISFTPQGDLIASANADKTVKIWRVRDGKAL 1439
Query: 101 TTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSS 160
TL GH V + ++ G LAS S+DN V LW+V L+GH D+V V F
Sbjct: 1440 KTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPD 1499
Query: 161 GKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGI 220
GK + S+S DK +R+WD + + ++ + H+ ++SV+ +P L + SADK ++ +
Sbjct: 1500 GKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWR- 1558
Query: 221 KHD-------------------SVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVAT 261
HD S DG + + W + Q + V +
Sbjct: 1559 SHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQIDGHLLTTLPQHQAGVMS 1618
Query: 262 VQFNKSGNLLACQVAGKTVEIYRVLDDSEAK 292
F+ G L T +I+R D +AK
Sbjct: 1619 AIFSPDGKTLISGSLDTTTKIWR-FDSQQAK 1648
Score = 95.5 bits (236), Expect = 6e-19
Identities = 93/431 (21%), Positives = 178/431 (40%), Gaps = 57/431 (13%)
Query: 312 LEATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRASKK-ICSISFCPST 370
LE ++G + D T+ G+++ + + +L T+ + + S+SF P
Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLWSRDG--RLFRTLNGHEDAVYSVSFSPDG 1125
Query: 371 PKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLS-TSH 429
+ G ++ ++ + KT+ GH V +V S D L S +S
Sbjct: 1126 QTIASGG-----SDKTIKLWQTSDGTLLKTIT----GHEQTVNNVYFSPDGKNLASASSD 1176
Query: 430 NAVKIWNPTTGSCLRTIDSGYGLCSLVL---PTNKYGLVGTKDGTIEIIDIGSGTCLEAI 486
+++K+W+ T+G L T+ +G+ + + P + G++D T+++ G L+ +
Sbjct: 1177 HSIKLWDTTSGQLLMTL-TGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTL 1235
Query: 487 EAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQL-------------- 532
H + S++ PD + + SAD +K W G+ K L
Sbjct: 1236 NGHQDWVNSLSFSPDGKTLASASADKTIKLWRIA----DGKLVKTLKGHNDSVWDVNFSS 1291
Query: 533 ------AVSNVRTMKM--------------NDDVLVVAISPDAKYIAVALLDSTVKVHFV 572
+ S T+K+ + V V PD+ IA A LD+T+++
Sbjct: 1292 DGKAIASASRDNTIKLWNRHGIELETFTGHSGGVYAVNFLPDSNIIASASLDNTIRLWQR 1351
Query: 573 DTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMA 632
L G+ V + DG +I T AD N+++W G K+L + ++
Sbjct: 1352 PLISPLEVLAGNS-GVYAVSFLHDGSIIATAGADGNIQLWHSQDGSLLKTL-PGNKAIYG 1409
Query: 633 VKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRS 692
+ F P+ + S D+ V W + L TL GH ++ + S G + + S D +
Sbjct: 1410 ISFTPQGDLIASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNT 1469
Query: 693 IRRWDRTEEQF 703
++ W+ ++ +F
Sbjct: 1470 VKLWNVSDGKF 1480
Score = 80.5 bits (197), Expect = 2e-14
Identities = 43/125 (34%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Query: 581 LYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTH 640
L GHK V+ + IS DG I +GS DK +K+W D G ++L H+D+V +V F P
Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLWSRD-GRLFRTLNGHEDAVYSVSFSPDGQ 1126
Query: 641 YVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWDRTE 700
+ S G D+ + W L T+ GH + + S G + + S D SI+ WD T
Sbjct: 1127 TIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTS 1186
Query: 701 EQFFL 705
Q +
Sbjct: 1187 GQLLM 1191
>YS00_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800
Length = 1258
Score = 173 bits (439), Expect = 2e-42
Identities = 149/593 (25%), Positives = 252/593 (42%), Gaps = 64/593 (10%)
Query: 108 GAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSS 167
G + + ++ G +LA+ D V +W+V L RGH + V VVF G+ L S
Sbjct: 643 GNILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASC 702
Query: 168 SKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHDSVDG 227
D+ +++W + C++ ++GH E++SV P L + S DK ++ + I+ DG
Sbjct: 703 GADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQ----DG 758
Query: 228 ASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLD 287
+ L G D V V F+ GN LA A T++++ V
Sbjct: 759 TCLQ--------------TLTGHT-----DWVRCVAFSPDGNTLASSAADHTIKLWDV-- 797
Query: 288 DSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPD 347
++ K R L++ + D T+ G+ + +
Sbjct: 798 ---SQGKCLRT-------------LKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHT 841
Query: 348 VFKLLHTIRASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQG 407
L I + + SI++ P + L + ++ + Q+ KTL G
Sbjct: 842 GECLKTYIGHTNSVYSIAYSPDSKI-----LVSGSGDRTIKLWDCQTHICIKTL----HG 892
Query: 408 HRSDVRSVTLSSDNSFLLSTS-HNAVKIWNPTTGSCLRTI--DSGYGLCSLVLPTNKYGL 464
H ++V SV S D L S +V++WN TG CL+ ++ + L P +
Sbjct: 893 HTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILA 952
Query: 465 VGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQK 524
G+ D T+++ D +G + ++E H + IA PD + + S D V+ W
Sbjct: 953 SGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNIST--- 1009
Query: 525 PGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGH 584
GQ + L ++ D V V P K IA D TVK+ + T + +L H
Sbjct: 1010 -GQCFQIL-------LEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEH 1061
Query: 585 KLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFS 644
+L M S DG L+ + SAD+++++W G C L H + V + F P + +
Sbjct: 1062 SDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIAT 1121
Query: 645 VGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
D+ V WD + + L TL GH ++ +A S G + + SHD+++R WD
Sbjct: 1122 CSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWD 1174
Score = 169 bits (429), Expect = 2e-41
Identities = 168/666 (25%), Positives = 282/666 (42%), Gaps = 95/666 (14%)
Query: 68 VTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSK 127
+ S A +P L+A D +R+ + G GH V + ++ G +LAS
Sbjct: 645 ILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGA 704
Query: 128 DNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIV 187
D +V LW V + L GH +V V F G+ L S+S DK +++WD+ C+Q +
Sbjct: 705 DENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTL 764
Query: 188 SGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLRL 247
+GH + V P L + +AD ++ WDV +
Sbjct: 765 TGHTDWVRCVAFSPDGNTLASSAADHTIKL------------------------WDVSQ- 799
Query: 248 FGEIQRQSKDR---VATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKE 304
G+ R K V +V F+ G LA +T++I+
Sbjct: 800 -GKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNY------------------- 839
Query: 305 KKHGKEPLEATENGHNNN----ENKEDNSTVTHGTIETSNPTITVPDV-----FKLLHTI 355
H E L+ T GH N+ D+ + G+ + TI + D K LH
Sbjct: 840 --HTGECLK-TYIGHTNSVYSIAYSPDSKILVSGS---GDRTIKLWDCQTHICIKTLHG- 892
Query: 356 RASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSV 415
+ ++CS++F P +LA ++L + L ++ ++ + K G+ V
Sbjct: 893 -HTNEVCSVAFSPDG--QTLACVSLDQSVRL---WNCRTGQCLKAW----YGNTDWALPV 942
Query: 416 TLSSDNSFLLSTSHN-AVKIWNPTTGSCLRTIDSG----YGLCSLVLPTNKYGLVGTKDG 470
S D L S S++ VK+W+ TG + +++ YG+ P ++ + D
Sbjct: 943 AFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIA--FSPDSQTLASASTDS 1000
Query: 471 TIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATK 530
++ + +I +G C + + H + ++ P TGSAD VK W GQ K
Sbjct: 1001 SVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNIST----GQCLK 1056
Query: 531 QLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLC 590
L+ + +D +L +A SPD + +A A D +V++ T + L GH V
Sbjct: 1057 TLS-------EHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYS 1109
Query: 591 MDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRR 650
S +G++I T S D+ +KIW G C K+L H + V + F P + S D+
Sbjct: 1110 AIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASASHDQT 1169
Query: 651 VNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD-RTEEQFFLEEEK 709
V WD + + GH + +A S G+ + +GS D+++R W+ +T E L+ +
Sbjct: 1170 VRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGE--CLQILR 1227
Query: 710 EKRLEE 715
KRL E
Sbjct: 1228 AKRLYE 1233
Score = 135 bits (339), Expect = 7e-31
Identities = 88/321 (27%), Positives = 147/321 (45%), Gaps = 18/321 (5%)
Query: 387 LEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHN-AVKIWNPTTGSCLRT 445
++ +S++ KTL GH +V SV D L S S + +K+W+ G+CL+T
Sbjct: 708 VKLWSVRDGVCIKTLT----GHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQT 763
Query: 446 ID--SGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKN 503
+ + + C P D TI++ D+ G CL +++H G +RS+A D
Sbjct: 764 LTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQ 823
Query: 504 SFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALL 563
+ +GS D +K W Y G+ K + + V +A SPD+K +
Sbjct: 824 TLASGSGDRTIKIWNYHT----GECLKTY-------IGHTNSVYSIAYSPDSKILVSGSG 872
Query: 564 DSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSL 623
D T+K+ T +L+GH V + S DG + S D+++++W G C K+
Sbjct: 873 DRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAW 932
Query: 624 FAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDF 683
+ + D + V F P + S D+ V WD + + +LEGH I+ +A S
Sbjct: 933 YGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQT 992
Query: 684 IVTGSHDRSIRRWDRTEEQFF 704
+ + S D S+R W+ + Q F
Sbjct: 993 LASASTDSSVRLWNISTGQCF 1013
Score = 132 bits (333), Expect = 3e-30
Identities = 98/356 (27%), Positives = 161/356 (44%), Gaps = 42/356 (11%)
Query: 378 LALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHN-AVKIWN 436
LA S ++ ++ + + + +TL + H VRSV S+D L S S + +KIWN
Sbjct: 783 LASSAADHTIKLWDVSQGKCLRTL----KSHTGWVRSVAFSADGQTLASGSGDRTIKIWN 838
Query: 437 PTTGSCLRTI----DSGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGS 492
TG CL+T +S Y + P +K + G+ D TI++ D + C++ + H
Sbjct: 839 YHTGECLKTYIGHTNSVYSIA--YSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNE 896
Query: 493 LRSIAALPDKNSFVTGSADHDVKFWEYQ----IKQKPGQATKQLAV------------SN 536
+ S+A PD + S D V+ W + +K G L V SN
Sbjct: 897 VCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILASGSN 956
Query: 537 VRTMKM---------------NDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSL 581
+T+K+ D + +A SPD++ +A A DS+V++ + T + F L
Sbjct: 957 DKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQCFQIL 1016
Query: 582 YGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHY 641
H V + G +I TGSAD +K+W + G C K+L H D ++ + + P
Sbjct: 1017 LEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQL 1076
Query: 642 VFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D+ V WD + L GH ++ S G+ I T S D++++ WD
Sbjct: 1077 LASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWD 1132
Score = 120 bits (300), Expect = 2e-26
Identities = 64/196 (32%), Positives = 103/196 (51%), Gaps = 7/196 (3%)
Query: 24 ITYDSSGKHLLS-PALEKIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAA 82
+ + G+ L S A E + +W VR G+C KTLT G V S+A P +A+
Sbjct: 690 VVFSPDGEILASCGADENVKLWSVRDGVCIKTLT------GHEHEVFSVAFHPDGETLAS 743
Query: 83 GYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGL 142
GD +I++ D GTC TL GH V + ++ G+ LAS + D+ + LWDV L
Sbjct: 744 ASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCL 803
Query: 143 FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPG 202
L+ H V V F + G+ L S S D+ +++W+ T C++ GH + ++S+ P
Sbjct: 804 RTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPD 863
Query: 203 ERYLVTGSADKELRFY 218
+ LV+GS D+ ++ +
Sbjct: 864 SKILVSGSGDRTIKLW 879
Score = 118 bits (295), Expect = 8e-26
Identities = 121/493 (24%), Positives = 202/493 (40%), Gaps = 66/493 (13%)
Query: 24 ITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAA 82
+ + G L S A + I +W V QG C +TL + + V S+A + +A+
Sbjct: 774 VAFSPDGNTLASSAADHTIKLWDVSQGKCLRTL------KSHTGWVRSVAFSADGQTLAS 827
Query: 83 GYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGL 142
G GD +I+I + G C T GH +V ++ Y+ +L SGS D + LWD +
Sbjct: 828 GSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICI 887
Query: 143 FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPG 202
L GH ++V V F G+ L S D+ +R+W+ T C++ G+ V P
Sbjct: 888 KTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPD 947
Query: 203 ERYLVTGSADKELR-------------------FYGIKHDSVDGASVNGGDDSSVSSKWD 243
+ L +GS DK ++ YGI + DSSV W+
Sbjct: 948 RQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSV-RLWN 1006
Query: 244 VL--RLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHR 301
+ + F +I + D V V F+ G ++A A TV+++ + K ++ H
Sbjct: 1007 ISTGQCF-QILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSE---HS 1062
Query: 302 KKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPD--VFKLLHTIRA-S 358
K P D + + + S + + D + + +R S
Sbjct: 1063 DKILGMAWSP---------------DGQLLASASADQS---VRLWDCCTGRCVGILRGHS 1104
Query: 359 KKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLS 418
++ S F P+ +A + ++ + Q + KTL GH + V + S
Sbjct: 1105 NRVYSAIFSPNGEI-----IATCSTDQTVKIWDWQQGKCLKTLT----GHTNWVFDIAFS 1155
Query: 419 SDNSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNKYGLVGTKDGTIEII 475
D L S SH+ V+IW+ TG C L S V P + G++D T+ I
Sbjct: 1156 PDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIW 1215
Query: 476 DIGSGTCLEAIEA 488
++ +G CL+ + A
Sbjct: 1216 NVKTGECLQILRA 1228
Score = 103 bits (258), Expect = 2e-21
Identities = 59/199 (29%), Positives = 99/199 (49%), Gaps = 7/199 (3%)
Query: 24 ITYDSSGKHLLSPALE-KIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAA 82
+ + GK + + + + + +W++ G C KTL+ S + +A +P L+A+
Sbjct: 1026 VVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEH------SDKILGMAWSPDGQLLAS 1079
Query: 83 GYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGL 142
D S+R+ D G C L GH V + ++ G ++A+ S D V +WD L
Sbjct: 1080 ASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCL 1139
Query: 143 FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPG 202
L GH + V D+ F GK L S+S D+ +R+WD++T C I GH + SV P
Sbjct: 1140 KTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPD 1199
Query: 203 ERYLVTGSADKELRFYGIK 221
+ +GS D+ +R + +K
Sbjct: 1200 GEVVASGSQDQTVRIWNVK 1218
Score = 103 bits (256), Expect = 3e-21
Identities = 82/326 (25%), Positives = 135/326 (41%), Gaps = 35/326 (10%)
Query: 403 IDLQGHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGLCSLVLPTNKY 462
+DL G+ D +T+ ++L + + V N C+ T G L + P +
Sbjct: 601 VDLSGY--DFSGLTVWQ--AYLQGVNLHDVDFANSDLSCCVFTETLGNILSAAFSPEGQL 656
Query: 463 GLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQ-- 520
D + + ++ SG L H +R + PD + AD +VK W +
Sbjct: 657 LATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVKLWSVRDG 716
Query: 521 --IKQKPGQATKQLAV------------SNVRTMKM---------------NDDVLVVAI 551
IK G + +V S +T+K+ D V VA
Sbjct: 717 VCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAF 776
Query: 552 SPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKI 611
SPD +A + D T+K+ V K +L H V + S+DG + +GS D+ +KI
Sbjct: 777 SPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKI 836
Query: 612 WGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHAD 671
W G+C K+ H +SV ++ + P + + S DR + WD + TL GH +
Sbjct: 837 WNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNE 896
Query: 672 IWCLAISNRGDFIVTGSHDRSIRRWD 697
+ +A S G + S D+S+R W+
Sbjct: 897 VCSVAFSPDGQTLACVSLDQSVRLWN 922
Score = 94.4 bits (233), Expect = 1e-18
Identities = 68/267 (25%), Positives = 113/267 (41%), Gaps = 35/267 (13%)
Query: 41 IAVWHVRQG----ICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDK 96
+ VW V+ G IC RG S V + +P ++A+ D ++++
Sbjct: 666 VRVWEVKSGKLLLIC----------RGHSNWVRFVVFSPDGEILASCGADENVKLWSVRD 715
Query: 97 GTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVV 156
G C TL GH+ V ++ ++ G LAS S D + LWD+ T L L GH D V V
Sbjct: 716 GVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVA 775
Query: 157 FLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELR 216
F G L SS+ D +++WD+ C++ + H + SV + L +GS D+ ++
Sbjct: 776 FSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIK 835
Query: 217 F-------------------YGIKHDSVDGASVNGGDDSSVSSKWDV-LRLFGEIQRQSK 256
Y I + V+G D ++ WD + +
Sbjct: 836 IWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTI-KLWDCQTHICIKTLHGHT 894
Query: 257 DRVATVQFNKSGNLLACQVAGKTVEIY 283
+ V +V F+ G LAC ++V ++
Sbjct: 895 NEVCSVAFSPDGQTLACVSLDQSVRLW 921
Score = 62.8 bits (151), Expect = 4e-09
Identities = 37/111 (33%), Positives = 58/111 (51%), Gaps = 6/111 (5%)
Query: 39 EKIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGT 98
+ + +W +QG C KTLT G + V IA +P ++A+ D ++RI D + G
Sbjct: 1126 QTVKIWDWQQGKCLKTLT------GHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGK 1179
Query: 99 CETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHR 149
C GH V+++ ++ G V+ASGS+D V +W+V L LR R
Sbjct: 1180 CHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGECLQILRAKR 1230
>HET1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1
Length = 1356
Score = 154 bits (390), Expect = 8e-37
Identities = 100/296 (33%), Positives = 143/296 (47%), Gaps = 14/296 (4%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNK 461
L+GH S V SV S+D + S S + +KIW+ +G+ +T++ G V P +
Sbjct: 837 LEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRE 896
Query: 462 YGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
G+ D TI+I D SGTC + +E HGG ++S+A PD +GS DH +K W+
Sbjct: 897 RVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWD--- 953
Query: 522 KQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSL 581
G T+ L VL VA SPD + +A D T+K+ + +L
Sbjct: 954 -AASGTCTQTLEGHG-------SSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTL 1005
Query: 582 YGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHY 641
GH V + S DG + +GS DK +KIW G C ++L H V +V F P
Sbjct: 1006 EGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQR 1065
Query: 642 VFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
V S D + WDA TLEGH +W +A S G + +GS D +I+ WD
Sbjct: 1066 VASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWD 1121
Score = 154 bits (389), Expect = 1e-36
Identities = 129/508 (25%), Positives = 213/508 (41%), Gaps = 69/508 (13%)
Query: 38 LEKIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKG 97
+ I+V CT+TL G +V S+A + +A+G D +I+I D+ G
Sbjct: 820 ISTISVVEAEWNACTQTL------EGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASG 873
Query: 98 TCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVF 157
T TL GH G+V ++ ++ +ASGS D + +WD T L GH +V V F
Sbjct: 874 TGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAF 933
Query: 158 LSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRF 217
G+++ S S D +++WD + C Q + GH S + SV P + + +GS DK ++
Sbjct: 934 SPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKI 993
Query: 218 YGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAG 277
+ D+ G + S V +V F+ G +A
Sbjct: 994 W----DTASGTCTQTLEGHGGS-------------------VWSVAFSPDGQRVASGSDD 1030
Query: 278 KTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIE 337
KT++I+ + + LE + D V G
Sbjct: 1031 KTIKIWDTASGT------------------CTQTLEGHGGWVQSVVFSPDGQRVASG--- 1069
Query: 338 TSNPTITVPDVFK--LLHTIRA-SKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQS 394
+ + TI + D T+ + S++F P + +A + ++ + S
Sbjct: 1070 SDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQR-----VASGSIDGTIKIWDAAS 1124
Query: 395 SETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTS-HNAVKIWNPTTGSCLRTIDSGYGLC 453
+T L+GH V SV S D + S S +KIW+ +G+C +T++ G
Sbjct: 1125 GTCTQT----LEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWV 1180
Query: 454 SLVL--PTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSAD 511
V P + G+ D TI+I D SGTC + +E HGG ++S+A PD +GS+D
Sbjct: 1181 QSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSD 1240
Query: 512 HDVKFWEYQIKQKPGQATKQLAVSNVRT 539
+ +K W+ G T+ L V + T
Sbjct: 1241 NTIKIWD----TASGTCTQTLNVGSTAT 1264
Score = 153 bits (386), Expect = 2e-36
Identities = 104/344 (30%), Positives = 161/344 (46%), Gaps = 29/344 (8%)
Query: 360 KICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSS 419
++ S++F P + +A +++ ++ + S +TL +GH S V SV S
Sbjct: 927 RVQSVAFSPDGQR-----VASGSDDHTIKIWDAASGTCTQTL----EGHGSSVLSVAFSP 977
Query: 420 DNSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNKYGLVGTKDGTIEIID 476
D + S S + +KIW+ +G+C +T++ G V P + G+ D TI+I D
Sbjct: 978 DGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWD 1037
Query: 477 IGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSN 536
SGTC + +E HGG ++S+ PD +GS DH +K W+ AVS
Sbjct: 1038 TASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWD--------------AVSG 1083
Query: 537 VRTMKMN---DDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDI 593
T + D V VA SPD + +A +D T+K+ + +L GH V +
Sbjct: 1084 TCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAF 1143
Query: 594 SSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNY 653
S DG + +GS D +KIW G C ++L H V +V F P V S D+ +
Sbjct: 1144 SPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKI 1203
Query: 654 WDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
WD TLEGH + +A S G + +GS D +I+ WD
Sbjct: 1204 WDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWD 1247
Score = 145 bits (365), Expect = 6e-34
Identities = 98/296 (33%), Positives = 139/296 (46%), Gaps = 14/296 (4%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL--PTNK 461
L+GH V SV S D + S S + +KIW+ +G+C +T++ G V P +
Sbjct: 879 LEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQ 938
Query: 462 YGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
G+ D TI+I D SGTC + +E HG S+ S+A PD +GS D +K W+
Sbjct: 939 RVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWD--- 995
Query: 522 KQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSL 581
G T+ L V VA SPD + +A D T+K+ + +L
Sbjct: 996 -TASGTCTQTLEGHG-------GSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTL 1047
Query: 582 YGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHY 641
GH V + S DG + +GS D +KIW G C ++L H DSV +V F P
Sbjct: 1048 EGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQR 1107
Query: 642 VFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
V S D + WDA TLEGH + +A S G + +GS D +I+ WD
Sbjct: 1108 VASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWD 1163
Score = 142 bits (359), Expect = 3e-33
Identities = 122/477 (25%), Positives = 202/477 (41%), Gaps = 63/477 (13%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + + G+ + S + +K I +W G T+TL G +V S+A +P +A
Sbjct: 846 SVAFSADGQRVASGSDDKTIKIWDTASGTGTQTL------EGHGGSVWSVAFSPDRERVA 899
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+G D +I+I D+ GTC TL GH G V ++ ++ G +ASGS D+ + +WD T
Sbjct: 900 SGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTC 959
Query: 142 LFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDP 201
L GH V V F G+++ S S DK +++WD + C Q + GH +WSV P
Sbjct: 960 TQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSP 1019
Query: 202 GERYLVTGSADKELRFYGIKHD------------------SVDGASVNGGDDSSVSSKWD 243
+ + +GS DK ++ + S DG V G D WD
Sbjct: 1020 DGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWD 1079
Query: 244 -VLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRK 302
V + D V +V F+ G +A T++I+ +
Sbjct: 1080 AVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGT------------- 1126
Query: 303 KEKKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFK--LLHTIRA-SK 359
+ LE ++ D V G+I+ TI + D T+
Sbjct: 1127 -----CTQTLEGHGGWVHSVAFSPDGQRVASGSID---GTIKIWDAASGTCTQTLEGHGG 1178
Query: 360 KICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSS 419
+ S++F P + +A ++ ++ + S +T L+GH V+SV S
Sbjct: 1179 WVQSVAFSPDGQR-----VASGSSDKTIKIWDTASGTCTQT----LEGHGGWVQSVAFSP 1229
Query: 420 DNSFLLS-TSHNAVKIWNPTTGSCLRTIDSG-YGLCSLVLPTNKYGLVGTKDGTIEI 474
D + S +S N +KIW+ +G+C +T++ G C TN Y + T G I+I
Sbjct: 1230 DGQRVASGSSDNTIKIWDTASGTCTQTLNVGSTATCLSFDYTNAY--INTNIGRIQI 1284
Score = 142 bits (358), Expect = 4e-33
Identities = 103/341 (30%), Positives = 159/341 (46%), Gaps = 25/341 (7%)
Query: 361 ICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSD 420
+ S++F P + +A ++ ++ + S +TL +GH V+SV S D
Sbjct: 886 VWSVAFSPDRER-----VASGSDDKTIKIWDAASGTCTQTL----EGHGGRVQSVAFSPD 936
Query: 421 NSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL---PTNKYGLVGTKDGTIEIID 476
+ S S + +KIW+ +G+C +T++ G+G L + P + G+ D TI+I D
Sbjct: 937 GQRVASGSDDHTIKIWDAASGTCTQTLE-GHGSSVLSVAFSPDGQRVASGSGDKTIKIWD 995
Query: 477 IGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSN 536
SGTC + +E HGGS+ S+A PD +GS D +K W+ G T+ L
Sbjct: 996 TASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWD----TASGTCTQTLEGHG 1051
Query: 537 VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSD 596
V V SPD + +A D T+K+ + +L GH V + S D
Sbjct: 1052 -------GWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPD 1104
Query: 597 GDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDA 656
G + +GS D +KIW G C ++L H V +V F P V S D + WDA
Sbjct: 1105 GQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDA 1164
Query: 657 DKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
TLEGH + +A S G + +GS D++I+ WD
Sbjct: 1165 ASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWD 1205
Score = 139 bits (351), Expect = 3e-32
Identities = 126/499 (25%), Positives = 207/499 (41%), Gaps = 80/499 (16%)
Query: 134 WDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSE 193
W+ +T L GH V V F + G+++ S S DK +++WD + Q + GH
Sbjct: 830 WNACTQT----LEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGS 885
Query: 194 IWSVDVDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQR 253
+WSV P + +GS DK ++ + D++ + L G
Sbjct: 886 VWSVAFSPDRERVASGSDDKTIKIW----------------DAASGTCTQTLEGHG---- 925
Query: 254 QSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLE 313
RV +V F+ G +A T++I+ A + + HG L
Sbjct: 926 ---GRVQSVAFSPDGQRVASGSDDHTIKIW----------DAASGTCTQTLEGHGSSVLS 972
Query: 314 ATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFK--LLHTIRA-SKKICSISFCPST 370
+ D V G+ + TI + D T+ + S++F P
Sbjct: 973 VAFS--------PDGQRVASGS---GDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDG 1021
Query: 371 PKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHN 430
+ +A ++ ++ + S +TL +GH V+SV S D + S S +
Sbjct: 1022 QR-----VASGSDDKTIKIWDTASGTCTQTL----EGHGGWVQSVVFSPDGQRVASGSDD 1072
Query: 431 -AVKIWNPTTGSCLRTIDS-GYGLCSLVL-PTNKYGLVGTKDGTIEIIDIGSGTCLEAIE 487
+KIW+ +G+C +T++ G + S+ P + G+ DGTI+I D SGTC + +E
Sbjct: 1073 HTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLE 1132
Query: 488 AHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDD-- 545
HGG + S+A PD +GS D +K W+ A S T +
Sbjct: 1133 GHGGWVHSVAFSPDGQRVASGSIDGTIKIWD--------------AASGTCTQTLEGHGG 1178
Query: 546 -VLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGS 604
V VA SPD + +A D T+K+ + +L GH V + S DG + +GS
Sbjct: 1179 WVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGS 1238
Query: 605 ADKNLKIWGLDFGDCHKSL 623
+D +KIW G C ++L
Sbjct: 1239 SDNTIKIWDTASGTCTQTL 1257
Score = 128 bits (321), Expect = 8e-29
Identities = 86/266 (32%), Positives = 125/266 (46%), Gaps = 19/266 (7%)
Query: 435 WNPTTGSCLRTIDSGYGLCSLVLPTNKYG---LVGTKDGTIEIIDIGSGTCLEAIEAHGG 491
WN +C +T++ G+G L + + G G+ D TI+I D SGT + +E HGG
Sbjct: 830 WN----ACTQTLE-GHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGG 884
Query: 492 SLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAI 551
S+ S+A PD+ +GS D +K W+ G T+ L R VA
Sbjct: 885 SVWSVAFSPDRERVASGSDDKTIKIWD----AASGTCTQTLEGHGGRVQS-------VAF 933
Query: 552 SPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKI 611
SPD + +A D T+K+ + +L GH VL + S DG + +GS DK +KI
Sbjct: 934 SPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKI 993
Query: 612 WGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHAD 671
W G C ++L H SV +V F P V S D+ + WD TLEGH
Sbjct: 994 WDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGW 1053
Query: 672 IWCLAISNRGDFIVTGSHDRSIRRWD 697
+ + S G + +GS D +I+ WD
Sbjct: 1054 VQSVVFSPDGQRVASGSDDHTIKIWD 1079
Score = 115 bits (288), Expect = 5e-25
Identities = 70/227 (30%), Positives = 104/227 (44%), Gaps = 11/227 (4%)
Query: 471 TIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATK 530
TI +++ C + +E HG S+ S+A D +GS D +K W+ G T+
Sbjct: 822 TISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWD----TASGTGTQ 877
Query: 531 QLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLC 590
L V VA SPD + +A D T+K+ + +L GH V
Sbjct: 878 TLEGHG-------GSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQS 930
Query: 591 MDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRR 650
+ S DG + +GS D +KIW G C ++L H SV++V F P V S D+
Sbjct: 931 VAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKT 990
Query: 651 VNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ WD TLEGH +W +A S G + +GS D++I+ WD
Sbjct: 991 IKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWD 1037
>TUP1_CANAL (P56093) Transcriptional repressor TUP1
Length = 514
Score = 125 bits (314), Expect = 5e-28
Identities = 100/351 (28%), Positives = 156/351 (43%), Gaps = 49/351 (13%)
Query: 387 LEFYSIQSSETNKTLAIDLQ---GHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCL 443
LE+Y + + +K L ID+ H S V V S D F+ + + +++N TTG +
Sbjct: 177 LEYYVLYNPAFSKDLDIDMVHSLDHSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELV 236
Query: 444 --------------RTIDSG--YGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIE 487
T SG Y P K G +D I I D+ + ++ +
Sbjct: 237 AKLIDESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILR 296
Query: 488 AHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVL 547
H + S+ PD + V+GS D V+ W+ + T Q ++ T+ + D V
Sbjct: 297 GHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLR--------TSQCSL----TLSIEDGVT 344
Query: 548 VVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLY--------GHKLPVLCMDISSDGDL 599
VA+SPD K IA LD TV+V + T F + GH+ V + S++G+
Sbjct: 345 TVAVSPDGKLIAAGSLDRTVRV-WDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQ 403
Query: 600 IVTGSADKNLKIWGLDF-----GDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYW 654
I +GS D+ +K+W L+ C + H D V++V P Y+ S KDR V +W
Sbjct: 404 IASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFW 463
Query: 655 DADKFERLLTLEGHHADIWCLAIS--NRG--DFIVTGSHDRSIRRWDRTEE 701
D LL L+GH + +A+S ++G TGS D R W T++
Sbjct: 464 DQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATGSGDCKARIWKWTKK 514
Score = 80.1 bits (196), Expect = 3e-14
Identities = 60/213 (28%), Positives = 102/213 (47%), Gaps = 24/213 (11%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + G L+S + ++ + +W +R C+ TL+ VT++A +P LIA
Sbjct: 304 SLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTLSI-------EDGVTTVAVSPDGKLIA 356
Query: 82 AGYGDGSIRILDSDKGTCETTL-------NGHKGAVTALRYNQAGSVLASGSKDNDVILW 134
AG D ++R+ DS G L NGH+ +V ++ ++ G +ASGS D V LW
Sbjct: 357 AGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLW 416
Query: 135 DVVGE-----TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSG 189
+ G+ T GH+D V V + ++S SKD+ + WD + + + ++ G
Sbjct: 417 HLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLMLQG 476
Query: 190 HHSEIWSVDVDPG----ERYLVTGSADKELRFY 218
H + + SV V E TGS D + R +
Sbjct: 477 HRNSVISVAVSLNSKGTEGIFATGSGDCKARIW 509
Score = 73.6 bits (179), Expect = 2e-12
Identities = 76/306 (24%), Positives = 128/306 (40%), Gaps = 52/306 (16%)
Query: 320 NNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAGLA 379
++NENK+DN+T + D++ I S+ F P LA
Sbjct: 243 SSNENKDDNTTAS-------------GDLY-----------IRSVCFSPDGKL-----LA 273
Query: 380 LSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTS-HNAVKIWNPT 438
+ L+ + + + K L+GH D+ S+ D L+S S +V+IW+
Sbjct: 274 TGAEDKLIRIWDLSTKRIIKI----LRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLR 329
Query: 439 TGSCLRTIDSGYGLCSL-VLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEA-------HG 490
T C T+ G+ ++ V P K G+ D T+ + D +G +E +++ H
Sbjct: 330 TSQCSLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHE 389
Query: 491 GSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVA 550
S+ S+A + +GS D VK W + G++ K+ + V + D VL V
Sbjct: 390 DSVYSVAFSNNGEQIASGSLDRTVKLWHLE-----GKSDKK-STCEVTYIGHKDFVLSVC 443
Query: 551 ISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDG----DLIVTGSAD 606
+PD +YI D V + L L GH+ V+ + +S + + TGS D
Sbjct: 444 CTPDNEYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATGSGD 503
Query: 607 KNLKIW 612
+IW
Sbjct: 504 CKARIW 509
Score = 68.2 bits (165), Expect = 1e-10
Identities = 52/225 (23%), Positives = 92/225 (40%), Gaps = 38/225 (16%)
Query: 106 HKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTD----------- 154
H V +R+++ G +A+G + GE + ++ D
Sbjct: 201 HSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDLYI 260
Query: 155 --VVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSAD 212
V F GK L + ++DK +R+WDL T+ ++I+ GH +I+S+D P LV+GS D
Sbjct: 261 RSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGD 320
Query: 213 KELRFYGIKHD-----------------SVDGASVNGGDDSSVSSKWDVLRLF------- 248
+ +R + ++ S DG + G WD F
Sbjct: 321 RSVRIWDLRTSQCSLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDS 380
Query: 249 -GEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRVLDDSEAK 292
E +D V +V F+ +G +A +TV+++ + S+ K
Sbjct: 381 GNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKK 425
Score = 66.2 bits (160), Expect = 4e-10
Identities = 58/244 (23%), Positives = 99/244 (39%), Gaps = 25/244 (10%)
Query: 5 YLRYEPAAA----FGVIASVDSN-----ITYDSSGKHLLSPALEKIAVWHVRQGICTKTL 55
Y+ Y PA + ++ S+D + + + GK + + + V++V G L
Sbjct: 180 YVLYNPAFSKDLDIDMVHSLDHSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELVAKL 239
Query: 56 TPPPPSRGPSPAVT--------SIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHK 107
+ T S+ +P L+A G D IRI D L GH+
Sbjct: 240 IDESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHE 299
Query: 108 GAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSS 167
+ +L + G L SGS D V +WD+ L D VT V GK + +
Sbjct: 300 QDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTL-SIEDGVTTVAVSPDGKLIAAG 358
Query: 168 SKDKFLRVWDLDTQHCMQIV-------SGHHSEIWSVDVDPGERYLVTGSADKELRFYGI 220
S D+ +RVWD T ++ + +GH ++SV + +GS D+ ++ + +
Sbjct: 359 SLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHL 418
Query: 221 KHDS 224
+ S
Sbjct: 419 EGKS 422
Score = 60.8 bits (146), Expect = 2e-08
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPS-RGPSPAVTSIASTPSSSL 79
+ + GK + + +L++ + VW G + L + G +V S+A + +
Sbjct: 344 TTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQ 403
Query: 80 IAAGYGDGSIRILDSD-----KGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILW 134
IA+G D ++++ + K TCE T GHK V ++ + SGSKD VI W
Sbjct: 404 IASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFW 463
Query: 135 DVVGETGLFRLRGHRDQVTDVVFLSSGKK----LVSSSKDKFLRVW 176
D L L+GHR+ V V + K + S D R+W
Sbjct: 464 DQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATGSGDCKARIW 509
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 584 HKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAH------DDSVMA----- 632
H V C+ S DG I TG +K +++ + G+ L DD+ A
Sbjct: 201 HSSVVCCVRFSRDGKFIATG-CNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDLY 259
Query: 633 ---VKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSH 689
V F P + + +D+ + WD + L GH DI+ L GD +V+GS
Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSG 319
Query: 690 DRSIRRWDRTEEQ 702
DRS+R WD Q
Sbjct: 320 DRSVRIWDLRTSQ 332
>TU12_SCHPO (Q9UUG8) Transcriptional repressor tup12
Length = 586
Score = 121 bits (304), Expect = 8e-27
Identities = 87/332 (26%), Positives = 141/332 (42%), Gaps = 38/332 (11%)
Query: 390 YSIQSSETNKTLAIDLQ-----GHRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLR 444
+++ S+ NK I +Q H S + V S+D FL + + A ++N TG +
Sbjct: 263 WTVTSNVPNKEPPISVQLLHTLEHTSVICYVRFSADGKFLATGCNRAAMVFNVETGKLIT 322
Query: 445 TIDSG--------YGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSI 496
+ Y P KY G +D I I DI + H + S+
Sbjct: 323 LLQEESSKREGDLYVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSL 382
Query: 497 AALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAK 556
D + V+GS D V W+ + A +Q + + +D V V SPD +
Sbjct: 383 DFSKDGKTLVSGSGDRTVCLWDVE-------AGEQKLI-----LHTDDGVTTVMFSPDGQ 430
Query: 557 YIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGL-- 614
+IA LD +++ + + L+GH+ V + S DG +V+GS D +K+W L
Sbjct: 431 FIAAGSLDKVIRI-WTSSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQC 489
Query: 615 ----------DFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLT 664
+ G C ++ H D +++V P ++ S KDR + +W D LT
Sbjct: 490 VSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLT 549
Query: 665 LEGHHADIWCLAISNRGDFIVTGSHDRSIRRW 696
L+GH+ + +A+S G TGS D R W
Sbjct: 550 LQGHNNSVISVAVSPNGHCFATGSGDLRARIW 581
Score = 93.6 bits (231), Expect = 2e-18
Identities = 62/204 (30%), Positives = 98/204 (47%), Gaps = 4/204 (1%)
Query: 19 SVDSNITYDSSGKHLLSPALEKIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSS 78
SV + + + GK L + V++V G L R V S+A +P
Sbjct: 288 SVICYVRFSADGKFLATGCNRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSPDGK 347
Query: 79 LIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVG 138
+A G D IRI D + L GH+ + +L +++ G L SGS D V LWDV
Sbjct: 348 YLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDV-- 405
Query: 139 ETGLFRLRGHRDQ-VTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSV 197
E G +L H D VT V+F G+ + + S DK +R+W + ++ + GH ++SV
Sbjct: 406 EAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIW-TSSGTLVEQLHGHEESVYSV 464
Query: 198 DVDPGERYLVTGSADKELRFYGIK 221
P +YLV+GS D ++ + ++
Sbjct: 465 AFSPDGKYLVSGSLDNTIKLWELQ 488
Score = 92.0 bits (227), Expect = 6e-18
Identities = 85/352 (24%), Positives = 138/352 (39%), Gaps = 46/352 (13%)
Query: 305 KKHGKEPLEATENGHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRASKKICSI 364
K G P A +N N+E+ + P I+V +LLHT+ + IC +
Sbjct: 238 KVSGNPPYPAEIIPTSNVPNREEKDWTVTSNVPNKEPPISV----QLLHTLEHTSVICYV 293
Query: 365 SFCP-----STPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAID--------------- 404
F +T N A + L+ +SS+ L +
Sbjct: 294 RFSADGKFLATGCNRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSPDGKYLATGV 353
Query: 405 ------------------LQGHRSDVRSVTLSSDNSFLLSTS-HNAVKIWNPTTGSCLRT 445
L GH ++ S+ S D L+S S V +W+ G
Sbjct: 354 EDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGEQKLI 413
Query: 446 IDSGYGLCSLVL-PTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNS 504
+ + G+ +++ P ++ G+ D I I SGT +E + H S+ S+A PD
Sbjct: 414 LHTDDGVTTVMFSPDGQFIAAGSLDKVIRIW-TSSGTLVEQLHGHEESVYSVAFSPDGKY 472
Query: 505 FVTGSADHDVKFWEYQ-IKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALL 563
V+GS D+ +K WE Q + K+ + D +L V +SPD K+I
Sbjct: 473 LVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSK 532
Query: 564 DSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLD 615
D T++ D+ L+L GH V+ + +S +G TGS D +IW +
Sbjct: 533 DRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDLRARIWSYE 584
Score = 89.0 bits (219), Expect = 5e-17
Identities = 61/209 (29%), Positives = 98/209 (46%), Gaps = 21/209 (10%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + GK L+S + ++ + +W V G L VT++ +P IA
Sbjct: 381 SLDFSKDGKTLVSGSGDRTVCLWDVEAGEQKLILHT-------DDGVTTVMFSPDGQFIA 433
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDV----- 136
AG D IRI S GT L+GH+ +V ++ ++ G L SGS DN + LW++
Sbjct: 434 AGSLDKVIRIWTSS-GTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSN 492
Query: 137 -----VGETGLFR--LRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSG 189
E G+ + GH+D + V GK ++S SKD+ ++ W D+ H + G
Sbjct: 493 VAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQG 552
Query: 190 HHSEIWSVDVDPGERYLVTGSADKELRFY 218
H++ + SV V P TGS D R +
Sbjct: 553 HNNSVISVAVSPNGHCFATGSGDLRARIW 581
Score = 87.0 bits (214), Expect = 2e-16
Identities = 47/170 (27%), Positives = 87/170 (50%), Gaps = 4/170 (2%)
Query: 530 KQLAVSNVRTMKMNDDVLV--VAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLP 587
K + + + K D+ V VA SPD KY+A + D +++ + + + L GH+
Sbjct: 319 KLITLLQEESSKREGDLYVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQE 378
Query: 588 VLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGK 647
+ +D S DG +V+GS D+ + +W ++ G+ K + DD V V F P ++ +
Sbjct: 379 IYSLDFSKDGKTLVSGSGDRTVCLWDVEAGE-QKLILHTDDGVTTVMFSPDGQFIAAGSL 437
Query: 648 DRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
D+ + W + + L GH ++ +A S G ++V+GS D +I+ W+
Sbjct: 438 DKVIRIWTSSG-TLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWE 486
Score = 57.4 bits (137), Expect = 2e-07
Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 20/171 (11%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
+ + + G+ + + +L+K I +W T + T G +V S+A +P +
Sbjct: 421 TTVMFSPDGQFIAAGSLDKVIRIW-------TSSGTLVEQLHGHEESVYSVAFSPDGKYL 473
Query: 81 AAGYGDGSIRILD------------SDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKD 128
+G D +I++ + + G C+ T GHK + ++ + G + SGSKD
Sbjct: 474 VSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSKD 533
Query: 129 NDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLD 179
+ W L+GH + V V +G + S D R+W +
Sbjct: 534 RTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDLRARIWSYE 584
Score = 55.1 bits (131), Expect = 9e-07
Identities = 43/183 (23%), Positives = 76/183 (41%), Gaps = 29/183 (15%)
Query: 106 HKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE--TGLFRLRGHRD---QVTDVVFLSS 160
H + +R++ G LA+G ++ G+ T L R+ V V F
Sbjct: 286 HTSVICYVRFSADGKFLATGCNRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSPD 345
Query: 161 GKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGI 220
GK L + +D+ +R+WD+ + ++++GH EI+S+D + LV+GS D+ +
Sbjct: 346 GKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCL--- 402
Query: 221 KHDSVDGASVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTV 280
WDV ++ + D V TV F+ G +A K +
Sbjct: 403 ---------------------WDVEAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLDKVI 441
Query: 281 EIY 283
I+
Sbjct: 442 RIW 444
Score = 46.6 bits (109), Expect = 3e-04
Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 588 VLC-MDISSDGDLIVTGSADKNLKIWGLDFGDC------HKSLFAHDDSVMAVKFVPKTH 640
V+C + S+DG + TG ++ ++ ++ G S D V +V F P
Sbjct: 289 VICYVRFSADGKFLATG-CNRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSPDGK 347
Query: 641 YVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
Y+ + +D+++ WD + L GH +I+ L S G +V+GS DR++ WD
Sbjct: 348 YLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWD 404
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1
Length = 604
Score = 113 bits (282), Expect = 3e-24
Identities = 88/316 (27%), Positives = 131/316 (40%), Gaps = 39/316 (12%)
Query: 408 HRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSG--------YGLCSLVLPT 459
H S V V S D ++ + + + +I++ TG L + Y P
Sbjct: 296 HESVVCCVRFSMDGKYVATGCNRSAQIYDVETGEKLCILQDENIDLTGDLYIRSVCFSPD 355
Query: 460 NKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEY 519
KY G +D I + DI S T H + S+ D + +GS D V+ W+
Sbjct: 356 GKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDI 415
Query: 520 QIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTF--KF 577
+ Q N + + D V VAISPD +++A LD +V+V + + +
Sbjct: 416 ETGQ------------NTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAER 463
Query: 578 FLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDF------------GDCHKSLFA 625
GHK V + S DG +V+GS DK +K+W L G C K+
Sbjct: 464 LEGPDGHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEG 523
Query: 626 HDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAI-----SNR 680
H D V++V P + +V S KDR V +WD L L+GH + +A SN
Sbjct: 524 HRDFVLSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSPVTGSNG 583
Query: 681 GDFIVTGSHDRSIRRW 696
+ TGS D R W
Sbjct: 584 VGYFATGSGDMRARIW 599
Score = 86.3 bits (212), Expect = 4e-16
Identities = 47/172 (27%), Positives = 89/172 (51%), Gaps = 5/172 (2%)
Query: 530 KQLAVSNVRTMKMNDDVLV--VAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLP 587
++L + + + D+ + V SPD KY+A D ++V + + + +GH+
Sbjct: 329 EKLCILQDENIDLTGDLYIRSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQD 388
Query: 588 VLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGK 647
+ +D S DG I +GS D+ +++W ++ G + S+ + +D V V P +V +
Sbjct: 389 IYSLDFSRDGRTIASGSGDRTVRLWDIETGQ-NTSVLSIEDGVTTVAISPDKQFVAAGSL 447
Query: 648 DRRVNYWDADKF--ERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
D+ V WD + ERL +GH ++ +A S G +V+GS D++I+ W+
Sbjct: 448 DKSVRVWDMRGYLAERLEGPDGHKDSVYSVAFSPDGRNLVSGSLDKTIKMWE 499
Score = 79.0 bits (193), Expect = 6e-14
Identities = 57/217 (26%), Positives = 98/217 (44%), Gaps = 29/217 (13%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + G+ + S + ++ + +W + G T L+ VT++A +P +A
Sbjct: 391 SLDFSRDGRTIASGSGDRTVRLWDIETGQNTSVLSI-------EDGVTTVAISPDKQFVA 443
Query: 82 AGYGDGSIRILDSDKGTCETTL---NGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVG 138
AG D S+R+ D +G L +GHK +V ++ ++ G L SGS D + +W++
Sbjct: 444 AGSLDKSVRVWDM-RGYLAERLEGPDGHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSA 502
Query: 139 ETGL------------FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQI 186
G+ GHRD V V + ++S SKD+ ++ WD T H +
Sbjct: 503 PRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLM 562
Query: 187 VSGHHSEIWSVDVDP-----GERYLVTGSADKELRFY 218
+ GH + + SV P G Y TGS D R +
Sbjct: 563 LQGHKNSVISVAPSPVTGSNGVGYFATGSGDMRARIW 599
Score = 78.6 bits (192), Expect = 7e-14
Identities = 49/154 (31%), Positives = 77/154 (49%), Gaps = 5/154 (3%)
Query: 68 VTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSK 127
+ S+ +P +A G D IR+ D T T +GH+ + +L +++ G +ASGS
Sbjct: 347 IRSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSG 406
Query: 128 DNDVILWDVVGETGL-FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLD--TQHCM 184
D V LWD+ ETG + D VT V + + + S DK +RVWD+ +
Sbjct: 407 DRTVRLWDI--ETGQNTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERL 464
Query: 185 QIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+ GH ++SV P R LV+GS DK ++ +
Sbjct: 465 EGPDGHKDSVYSVAFSPDGRNLVSGSLDKTIKMW 498
Score = 63.9 bits (154), Expect = 2e-09
Identities = 61/256 (23%), Positives = 109/256 (41%), Gaps = 31/256 (12%)
Query: 461 KYGLVG-TKDGTIEIIDIGSGTCL---EAIEAHGGS-LRSIAALPDKNSFVTGSADHDVK 515
KY G + I ++ G C+ E I+ G +RS+ PD TG+ D ++
Sbjct: 310 KYVATGCNRSAQIYDVETGEKLCILQDENIDLTGDLYIRSVCFSPDGKYLATGAEDKLIR 369
Query: 516 FWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTF 575
W+ Q + + N D+ + S D + IA D TV++ ++T
Sbjct: 370 VWDIQSR----------TIRNT-FHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIETG 418
Query: 576 KFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLD--FGDCHKSLFAHDDSVMAV 633
+ S+ + V + IS D + GS DK++++W + + + H DSV +V
Sbjct: 419 QN-TSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERLEGPDGHKDSVYSV 477
Query: 634 KFVPKTHYVFSVGKDRRVNYWDAD-----------KFERLL-TLEGHHADIWCLAISNRG 681
F P + S D+ + W+ K R + T EGH + +A++
Sbjct: 478 AFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPDS 537
Query: 682 DFIVTGSHDRSIRRWD 697
++++GS DR ++ WD
Sbjct: 538 QWVLSGSKDRGVQFWD 553
Score = 60.5 bits (145), Expect = 2e-08
Identities = 51/207 (24%), Positives = 89/207 (42%), Gaps = 29/207 (14%)
Query: 106 HKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVT------DVVFLS 159
H+ V +R++ G +A+G + ++DV L L+ +T V F
Sbjct: 296 HESVVCCVRFSMDGKYVATGC-NRSAQIYDVETGEKLCILQDENIDLTGDLYIRSVCFSP 354
Query: 160 SGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYG 219
GK L + ++DK +RVWD+ ++ GH +I+S+D R + +GS D+ +R +
Sbjct: 355 DGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWD 414
Query: 220 IK----------HDSVDGASVN--------GGDDSSVSSKWDVLRLFGEIQR---QSKDR 258
I+ D V +++ G D SV WD+ E KD
Sbjct: 415 IETGQNTSVLSIEDGVTTVAISPDKQFVAAGSLDKSV-RVWDMRGYLAERLEGPDGHKDS 473
Query: 259 VATVQFNKSGNLLACQVAGKTVEIYRV 285
V +V F+ G L KT++++ +
Sbjct: 474 VYSVAFSPDGRNLVSGSLDKTIKMWEL 500
Score = 50.4 bits (119), Expect = 2e-05
Identities = 37/133 (27%), Positives = 58/133 (42%), Gaps = 20/133 (15%)
Query: 407 GHRSDVRSVTLSSDNSFLLSTS-HNAVKIWN------------PTTGSCLRTIDS--GYG 451
GH+ V SV S D L+S S +K+W P G C++T + +
Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFV 528
Query: 452 LCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNS-----FV 506
L + P +++ L G+KD ++ D +G ++ H S+ S+A P S F
Sbjct: 529 LSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSPVTGSNGVGYFA 588
Query: 507 TGSADHDVKFWEY 519
TGS D + W Y
Sbjct: 589 TGSGDMRARIWSY 601
>WDS_DROME (Q9V3J8) Will die slowly protein
Length = 361
Score = 112 bits (279), Expect = 6e-24
Identities = 91/361 (25%), Positives = 164/361 (45%), Gaps = 31/361 (8%)
Query: 309 KEPLEATENGHNN---NENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRA-SKKICSI 364
++PL +G N+ N + +T + + ++ +++V + L T+ +K + ++
Sbjct: 19 QQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAV 78
Query: 365 SFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFL 424
F P+ LA S + L++ + + KT++ GH+ + V SSD+ L
Sbjct: 79 KFSPNGE-----WLASSSADKLIKIWGAYDGKFEKTIS----GHKLGISDVAWSSDSRLL 129
Query: 425 LSTSHN-AVKIWNPTTGSCLRTID--SGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGT 481
+S S + +K+W +TG L+T+ S Y C P + + G+ D ++ I D+ +G
Sbjct: 130 VSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK 189
Query: 482 CLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMK 541
CL+ + AH + ++ D + V+ S D + W+ GQ K L +
Sbjct: 190 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD----TASGQCLKTLIDDD----- 240
Query: 542 MNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDIS---SDGD 598
N V V SP+ KYI A LD+T+K+ K + GHK C+ + + G
Sbjct: 241 -NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 299
Query: 599 LIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVG--KDRRVNYWDA 656
IV+GS D + IW L + + L H D+V+ P + + S D+ + W +
Sbjct: 300 WIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKS 359
Query: 657 D 657
D
Sbjct: 360 D 360
Score = 94.4 bits (233), Expect = 1e-18
Identities = 84/325 (25%), Positives = 130/325 (39%), Gaps = 58/325 (17%)
Query: 379 ALSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHNA-VKIWNP 437
A + +N+ S S + N TL L GH V +V S + +L S+S + +KIW
Sbjct: 42 ATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIW-- 99
Query: 438 TTGSCLRTIDSGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIA 497
G DG E + I H + +A
Sbjct: 100 ----------------------------GAYDGKFE----------KTISGHKLGISDVA 121
Query: 498 ALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDD-VLVVAISPDAK 556
D V+GS D +K WE + +++T+K + + V +P +
Sbjct: 122 WSSDSRLLVSGSDDKTLKVWELSTGK------------SLKTLKGHSNYVFCCNFNPQSN 169
Query: 557 YIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDF 616
I D +V++ V T K +L H PV + + DG LIV+ S D +IW
Sbjct: 170 LIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 229
Query: 617 GDCHKSLFAHDDS-VMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCL 675
G C K+L D+ V VKF P Y+ + D + WD K + L T GH + +C+
Sbjct: 230 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 289
Query: 676 AIS---NRGDFIVTGSHDRSIRRWD 697
+ G +IV+GS D + W+
Sbjct: 290 FANFSVTGGKWIVSGSEDNMVYIWN 314
Score = 87.4 bits (215), Expect = 2e-16
Identities = 51/157 (32%), Positives = 77/157 (48%)
Query: 546 VLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSA 605
V V SP+ +++A + D +K+ KF ++ GHKL + + SSD L+V+GS
Sbjct: 75 VSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSD 134
Query: 606 DKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTL 665
DK LK+W L G K+L H + V F P+++ + S D V WD + L TL
Sbjct: 135 DKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTL 194
Query: 666 EGHHADIWCLAISNRGDFIVTGSHDRSIRRWDRTEEQ 702
H + + + G IV+ S+D R WD Q
Sbjct: 195 PAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ 231
Score = 86.3 bits (212), Expect = 4e-16
Identities = 53/199 (26%), Positives = 94/199 (46%), Gaps = 8/199 (4%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
S + + +G+ L S + +K I +W G KT++ G ++ +A + S L+
Sbjct: 76 SAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS------GHKLGISDVAWSSDSRLL 129
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGET 140
+G D ++++ + G TL GH V +N +++ SGS D V +WDV
Sbjct: 130 VSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK 189
Query: 141 GLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQ-IVSGHHSEIWSVDV 199
L L H D V+ V F G +VSSS D R+WD + C++ ++ + + V
Sbjct: 190 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 249
Query: 200 DPGERYLVTGSADKELRFY 218
P +Y++ + D L+ +
Sbjct: 250 SPNGKYILAATLDNTLKLW 268
Score = 82.0 bits (201), Expect = 7e-15
Identities = 60/247 (24%), Positives = 109/247 (43%), Gaps = 21/247 (8%)
Query: 57 PPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYN 116
P PS GP+ + P ++ + + T + TL GH AV+A++++
Sbjct: 23 PTAPS-GPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFS 81
Query: 117 QAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVW 176
G LAS S D + +W + GH+ ++DV + S + LVS S DK L+VW
Sbjct: 82 PNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVW 141
Query: 177 DLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK-----------HDSV 225
+L T ++ + GH + ++ + +P +V+GS D+ +R + ++ D V
Sbjct: 142 ELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPV 201
Query: 226 DGASVNGGDDSSVSSKWDVL-RLFGEIQRQ--------SKDRVATVQFNKSGNLLACQVA 276
N VSS +D L R++ Q V+ V+F+ +G +
Sbjct: 202 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 261
Query: 277 GKTVEIY 283
T++++
Sbjct: 262 DNTLKLW 268
Score = 72.8 bits (177), Expect = 4e-12
Identities = 45/180 (25%), Positives = 85/180 (47%), Gaps = 10/180 (5%)
Query: 39 EKIAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGT 98
E + +W VR G C KTL S V+++ SLI + DG RI D+ G
Sbjct: 178 ESVRIWDVRTGKCLKTLP------AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ 231
Query: 99 C-ETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVF 157
C +T ++ V+ ++++ G + + + DN + LWD L GH+++ +
Sbjct: 232 CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFA 291
Query: 158 ---LSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKE 214
++ GK +VS S+D + +W+L ++ +Q + GH + P E + + + + +
Sbjct: 292 NFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALEND 351
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.1.129)
(MHCK B)
Length = 732
Score = 109 bits (273), Expect = 3e-23
Identities = 92/385 (23%), Positives = 176/385 (44%), Gaps = 30/385 (7%)
Query: 317 NGHNNNENKEDNSTVTHGTIETSNPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLA 376
N +N+N N +NS+++ +E S+ + D + S +++ K+
Sbjct: 370 NNNNSNNNNNNNSSISKSLVEISSGSKERNDRDSPSRQLFVSNDGNTLNTNKERSKSKSI 429
Query: 377 GLA---LSLNNNLLEFYSIQSSETNKTLAIDLQGHRSDVRSVTLSSDNSFLLSTSHNAVK 433
L + +NN E ++++ + +T+ +G+ V S DN S N+++
Sbjct: 430 DLEKPEILINNKKKESINLETIKLIETI----KGYH--VTSHLCICDNLLFTGCSDNSIR 483
Query: 434 IWNPTTGS--CLRTIDSGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGG 491
+++ + + C++T+ G + ++Y G+ D +I++ D+ C+ +E H
Sbjct: 484 VYDYKSQNMECVQTLKGHEGPVESICYNDQYLFSGSSDHSIKVWDLKKLRCIFTLEGHDK 543
Query: 492 SLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAI 551
+ ++ L DK F +GS+D +K W+ + + K S+ R +K +
Sbjct: 544 PVHTVL-LNDKYLF-SGSSDKTIKVWDLKTLE-----CKYTLESHARAVK--------TL 588
Query: 552 SPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKI 611
+Y+ D T+KV + TF+ +L GH V + I G + +GS DK +++
Sbjct: 589 CISGQYLFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICIL--GTNLYSGSYDKTIRV 646
Query: 612 WGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHAD 671
W L +C +L HD V + K +F+ D + WD + TLEGH+A
Sbjct: 647 WNLKSLECSATLRGHDRWVEHMVICDKL--LFTASDDNTIKIWDLETLRCNTTLEGHNAT 704
Query: 672 IWCLAISNRGDFIVTGSHDRSIRRW 696
+ CLA+ +++ SHD+SIR W
Sbjct: 705 VQCLAVWEDKKCVISCSHDQSIRVW 729
Score = 81.3 bits (199), Expect = 1e-14
Identities = 51/146 (34%), Positives = 76/146 (51%), Gaps = 8/146 (5%)
Query: 78 SLIAAGYGDGSIRILD--SDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWD 135
+L+ G D SIR+ D S C TL GH+G V ++ YN L SGS D+ + +WD
Sbjct: 471 NLLFTGCSDNSIRVYDYKSQNMECVQTLKGHEGPVESICYND--QYLFSGSSDHSIKVWD 528
Query: 136 VVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIW 195
+ +F L GH V V L + K L S S DK ++VWDL T C + H +
Sbjct: 529 LKKLRCIFTLEGHDKPVHTV--LLNDKYLFSGSSDKTIKVWDLKTLECKYTLESHARAVK 586
Query: 196 SVDVDPGERYLVTGSADKELRFYGIK 221
++ + +YL +GS DK ++ + +K
Sbjct: 587 TLCI--SGQYLFSGSNDKTIKVWDLK 610
Score = 77.8 bits (190), Expect = 1e-13
Identities = 75/350 (21%), Positives = 147/350 (41%), Gaps = 54/350 (15%)
Query: 303 KEKKHGKEP---LEATENGHNNNENKEDNSTVTHGTIETSNPTITVP---------DVFK 350
KE+ P L + +G+ N NKE + + + I+ P I + + K
Sbjct: 396 KERNDRDSPSRQLFVSNDGNTLNTNKERSKSKS---IDLEKPEILINNKKKESINLETIK 452
Query: 351 LLHTIRASKKICSISFCPSTPKNSLAGLALSLNNNLLEFYSIQSSETNKTLAIDLQGHRS 410
L+ TI+ + C + L ++N + Y +S N L+GH
Sbjct: 453 LIETIKGYHVTSHLCICDNL-------LFTGCSDNSIRVYDYKSQ--NMECVQTLKGHEG 503
Query: 411 DVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYGLVGTKDG 470
V S+ + F S+ H+ +K+W+ C+ T++ VL +KY G+ D
Sbjct: 504 PVESICYNDQYLFSGSSDHS-IKVWDLKKLRCIFTLEGHDKPVHTVLLNDKYLFSGSSDK 562
Query: 471 TIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWE-------YQIKQ 523
TI++ D+ + C +E+H +++++ +GS D +K W+ Y +K
Sbjct: 563 TIKVWDLKTLECKYTLESHARAVKTLCI--SGQYLFSGSNDKTIKVWDLKTFRCNYTLKG 620
Query: 524 KP---------------GQATKQLAVSNVRTMKMN-----DDVLVVAISPDAKYIAVALL 563
G K + V N+++++ + D V + K + A
Sbjct: 621 HTKWVTTICILGTNLYSGSYDKTIRVWNLKSLECSATLRGHDRWVEHMVICDKLLFTASD 680
Query: 564 DSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWG 613
D+T+K+ ++T + +L GH V C+ + D +++ S D+++++WG
Sbjct: 681 DNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKKCVISCSHDQSIRVWG 730
Score = 72.4 bits (176), Expect = 5e-12
Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 17/195 (8%)
Query: 503 NSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVAL 562
N TG +D+ ++ ++Y K + V+T+K ++ V +I + +Y+
Sbjct: 471 NLLFTGCSDNSIRVYDY----------KSQNMECVQTLKGHEGP-VESICYNDQYLFSGS 519
Query: 563 LDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKS 622
D ++KV + + +L GH PV + ++ + +GS+DK +K+W L +C +
Sbjct: 520 SDHSIKVWDLKKLRCIFTLEGHDKPVHTVLLNDK--YLFSGSSDKTIKVWDLKTLECKYT 577
Query: 623 LFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGD 682
L +H +V + Y+FS D+ + WD F TL+GH W I G
Sbjct: 578 LESHARAVKTLCI--SGQYLFSGSNDKTIKVWDLKTFRCNYTLKGHTK--WVTTICILGT 633
Query: 683 FIVTGSHDRSIRRWD 697
+ +GS+D++IR W+
Sbjct: 634 NLYSGSYDKTIRVWN 648
Score = 69.7 bits (169), Expect = 3e-11
Identities = 53/190 (27%), Positives = 92/190 (47%), Gaps = 13/190 (6%)
Query: 31 KHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSI 89
K+L S + +K I VW ++ C TL + AV ++ S + +G D +I
Sbjct: 553 KYLFSGSSDKTIKVWDLKTLECKYTL------ESHARAVKTLCI--SGQYLFSGSNDKTI 604
Query: 90 RILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHR 149
++ D C TL GH VT + G+ L SGS D + +W++ LRGH
Sbjct: 605 KVWDLKTFRCNYTLKGHTKWVTTICI--LGTNLYSGSYDKTIRVWNLKSLECSATLRGHD 662
Query: 150 DQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTG 209
V +V K L ++S D +++WDL+T C + GH++ + + V ++ +++
Sbjct: 663 RWVEHMVICD--KLLFTASDDNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKKCVISC 720
Query: 210 SADKELRFYG 219
S D+ +R +G
Sbjct: 721 SHDQSIRVWG 730
>TU11_SCHPO (Q09715) Transcriptional repressor tup11
Length = 614
Score = 107 bits (268), Expect = 1e-22
Identities = 81/309 (26%), Positives = 130/309 (41%), Gaps = 33/309 (10%)
Query: 408 HRSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSG--------YGLCSLVLPT 459
H S V V S++ +L + + A +++ TG L T+ Y P
Sbjct: 312 HPSVVCCVKFSNNGKYLATGCNQAANVFDVQTGKKLFTLHEESPDPSRDLYVRTIAFSPD 371
Query: 460 NKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEY 519
KY + GT+D I++ D+ + H + S+ + V+GS D + W+
Sbjct: 372 GKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDV 431
Query: 520 QIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFL 579
+ GQ +L + N V +AISP+ ++IAV LD ++V V
Sbjct: 432 ET----GQCILKLEIEN--------GVTAIAISPNDQFIAVGSLDQIIRVWSVSG-TLVE 478
Query: 580 SLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDF------------GDCHKSLFAHD 627
L GHK V + S D ++++GS DK +K+W L G C + H
Sbjct: 479 RLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHT 538
Query: 628 DSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTG 687
D V++V P + + S KDR + +WD + LT +GH + + S G +G
Sbjct: 539 DFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASG 598
Query: 688 SHDRSIRRW 696
S D R W
Sbjct: 599 SGDLRARIW 607
Score = 107 bits (266), Expect = 2e-22
Identities = 64/212 (30%), Positives = 111/212 (52%), Gaps = 4/212 (1%)
Query: 407 GHRSDVRSVTLSSDNSFLLSTSHN-AVKIWNPTTGSCLRTIDSGYGLCSLVL-PTNKYGL 464
GH D+ S+ S + F++S S + ++W+ TG C+ ++ G+ ++ + P +++
Sbjct: 400 GHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIA 459
Query: 465 VGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQK 524
VG+ D I + + SGT +E +E H S+ SIA PD + ++GS D +K WE Q +
Sbjct: 460 VGSLDQIIRVWSV-SGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRS 518
Query: 525 PG-QATKQLAVSNVRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYG 583
G A K + D VL VA+SPD+++ D +++ + T + +L+ G
Sbjct: 519 VGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQG 578
Query: 584 HKLPVLCMDISSDGDLIVTGSADKNLKIWGLD 615
HK V+ + S DG +GS D +IW +D
Sbjct: 579 HKNSVISVCFSPDGRQFASGSGDLRARIWSID 610
Score = 81.6 bits (200), Expect = 9e-15
Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 21/211 (9%)
Query: 23 NITYDSSGKHLLSPALEKIA-VWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + +G+ ++S + ++ A +W V G C L VT+IA +P+ IA
Sbjct: 407 SLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEI-------ENGVTAIAISPNDQFIA 459
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVG--E 139
G D IR+ S GT L GHK +V ++ ++ S+L SGS D + +W++
Sbjct: 460 VGSLDQIIRVW-SVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRS 518
Query: 140 TGLFRLR----------GHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSG 189
GL ++ GH D V V + +S SKD+ ++ WDL T G
Sbjct: 519 VGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQG 578
Query: 190 HHSEIWSVDVDPGERYLVTGSADKELRFYGI 220
H + + SV P R +GS D R + I
Sbjct: 579 HKNSVISVCFSPDGRQFASGSGDLRARIWSI 609
Score = 77.0 bits (188), Expect = 2e-13
Identities = 41/152 (26%), Positives = 74/152 (47%), Gaps = 2/152 (1%)
Query: 546 VLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSA 605
V +A SPD KY+ D +K+ + T K GH+ + +D S +G IV+GS
Sbjct: 363 VRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSG 422
Query: 606 DKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTL 665
D+ ++W ++ G C L ++ V A+ P ++ D+ + W + L
Sbjct: 423 DRTARLWDVETGQCILKL-EIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSG-TLVERL 480
Query: 666 EGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
EGH ++ +A S +++GS D++I+ W+
Sbjct: 481 EGHKESVYSIAFSPDSSILLSGSLDKTIKVWE 512
Score = 76.3 bits (186), Expect = 4e-13
Identities = 49/171 (28%), Positives = 81/171 (46%), Gaps = 14/171 (8%)
Query: 63 GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVL 122
G + S+ + + I +G GD + R+ D + G C L G VTA+ + +
Sbjct: 400 GHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENG-VTAIAISPNDQFI 458
Query: 123 ASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQH 182
A GS D + +W V G T + RL GH++ V + F L+S S DK ++VW+L
Sbjct: 459 AVGSLDQIIRVWSVSG-TLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATR 517
Query: 183 ------------CMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK 221
C +GH + SV V P R+ ++GS D+ ++F+ ++
Sbjct: 518 SVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQ 568
Score = 68.6 bits (166), Expect = 8e-11
Identities = 57/239 (23%), Positives = 103/239 (42%), Gaps = 34/239 (14%)
Query: 106 HKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGH-----RD-QVTDVVFLS 159
H V ++++ G LA+G + ++DV LF L RD V + F
Sbjct: 312 HPSVVCCVKFSNNGKYLATGC-NQAANVFDVQTGKKLFTLHEESPDPSRDLYVRTIAFSP 370
Query: 160 SGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYG 219
GK LV+ ++D+ +++WDL TQ + SGH +I+S+D R++V+GS D+ R +
Sbjct: 371 DGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWD 430
Query: 220 IK----------HDSVDGASVNGGDD-------SSVSSKWDVLRLFGEIQRQSKDRVATV 262
++ + V +++ D + W V E K+ V ++
Sbjct: 431 VETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSI 490
Query: 263 QFNKSGNLLACQVAGKTVEIYRVLDDSEAKRKAKRRVHRKKEKKHGKEPLEATENGHNN 321
F+ ++L KT++++ + +A R V K G +AT GH +
Sbjct: 491 AFSPDSSILLSGSLDKTIKVWEL--------QATRSVGLSAIKPEG--ICKATYTGHTD 539
Score = 68.2 bits (165), Expect = 1e-10
Identities = 66/316 (20%), Positives = 129/316 (39%), Gaps = 38/316 (12%)
Query: 410 SDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYGLVGTKD 469
SD + ++ S+ ++ + +++N + + T++ +C + N L +
Sbjct: 277 SDTEAARKTTSQSWYVTYNPACKRVFNI---NLVHTLEHPSVVCCVKFSNNGKYLATGCN 333
Query: 470 GTIEIIDIGSGTCLEAIEAHGGS------LRSIAALPDKNSFVTGSADHDVKFWEYQIKQ 523
+ D+ +G L + +R+IA PD VTG+ D +K W+
Sbjct: 334 QAANVFDVQTGKKLFTLHEESPDPSRDLYVRTIAFSPDGKYLVTGTEDRQIKLWD----- 388
Query: 524 KPGQATKQLAVSNVRTMKMN--DDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSL 581
L+ VR + D+ + S + ++I D T ++ V+T + L L
Sbjct: 389 --------LSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKL 440
Query: 582 YGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHY 641
V + IS + I GS D+ +++W + G + L H +SV ++ F P +
Sbjct: 441 EIEN-GVTAIAISPNDQFIAVGSLDQIIRVWSVS-GTLVERLEGHKESVYSIAFSPDSSI 498
Query: 642 VFSVGKDRRVNYWDADKFERL------------LTLEGHHADIWCLAISNRGDFIVTGSH 689
+ S D+ + W+ + T GH + +A+S + ++GS
Sbjct: 499 LLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSK 558
Query: 690 DRSIRRWDRTEEQFFL 705
DRS++ WD Q +L
Sbjct: 559 DRSMQFWDLQTGQSYL 574
Score = 62.4 bits (150), Expect = 5e-09
Identities = 42/136 (30%), Positives = 65/136 (46%), Gaps = 13/136 (9%)
Query: 584 HKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFA-HDDS--------VMAVK 634
H V C+ S++G + TG ++ ++ + G K LF H++S V +
Sbjct: 312 HPSVVCCVKFSNNGKYLATG-CNQAANVFDVQTG---KKLFTLHEESPDPSRDLYVRTIA 367
Query: 635 FVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIR 694
F P Y+ + +DR++ WD + GH DI+ L S+ G FIV+GS DR+ R
Sbjct: 368 FSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTAR 427
Query: 695 RWDRTEEQFFLEEEKE 710
WD Q L+ E E
Sbjct: 428 LWDVETGQCILKLEIE 443
Score = 61.6 bits (148), Expect = 9e-09
Identities = 36/129 (27%), Positives = 59/129 (44%), Gaps = 12/129 (9%)
Query: 63 GPSPAVTSIASTPSSSLIAAGYGDGSIRILD------------SDKGTCETTLNGHKGAV 110
G +V SIA +P SS++ +G D +I++ + +G C+ T GH V
Sbjct: 482 GHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFV 541
Query: 111 TALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKD 170
++ + SGSKD + WD+ +GH++ V V F G++ S S D
Sbjct: 542 LSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGD 601
Query: 171 KFLRVWDLD 179
R+W +D
Sbjct: 602 LRARIWSID 610
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1
(Flocculation suppressor protein) (Repressor AER2)
Length = 713
Score = 107 bits (267), Expect = 1e-22
Identities = 91/354 (25%), Positives = 144/354 (39%), Gaps = 53/354 (14%)
Query: 384 NNLLEFYSIQSSETNKTLAID--LQGHRSDV--RSVTLSSDNSFLLSTSHNAVKIWNPTT 439
N + Y + L+ D HR+ + + T S+DN+ + +T+ + T+
Sbjct: 364 NKTTQVYRVSDGSLVARLSDDSAANNHRNSITENNTTTSTDNNTMTTTTTTTITTTAMTS 423
Query: 440 GSCLRTIDSGYGLCS-----------LVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEA 488
+ L S P K+ G +D I I DI + + ++
Sbjct: 424 AAELAKDVENLNTSSSPSSDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQG 483
Query: 489 HGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMKMNDDVLV 548
H + S+ P + V+GS D V+ W+ + GQ + T+ + D V
Sbjct: 484 HEQDIYSLDYFPSGDKLVSGSGDRTVRIWDL----RTGQCSL--------TLSIEDGVTT 531
Query: 549 VAISP-DAKYIAVALLDSTVKVHFVDTFKFFLSL-------YGHKLPVLCMDISSDGDLI 600
VA+SP D KYIA LD V+V +T L GHK V + + DG +
Sbjct: 532 VAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSV 591
Query: 601 VTGSADKNLKIWGL------------DFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKD 648
V+GS D+++K+W L + G C + H D V++V Y+ S KD
Sbjct: 592 VSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKD 651
Query: 649 RRVNYWDADKFERLLTLEGHHADIWCLAISNRG------DFIVTGSHDRSIRRW 696
R V +WD LL L+GH + +A++N + TGS D R W
Sbjct: 652 RGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIW 705
Score = 81.6 bits (200), Expect = 9e-15
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 30/221 (13%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + GK L + A ++ I +W + L +G + S+ PS +
Sbjct: 448 SVCFSPDGKFLATGAEDRLIRIWDIENRKIVMIL------QGHEQDIYSLDYFPSGDKLV 501
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+G GD ++RI D G C TL+ G T G +A+GS D V +WD ETG
Sbjct: 502 SGSGDRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWD--SETG 559
Query: 142 LFRLR---------GHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQH---------- 182
R GH+D V VVF G+ +VS S D+ +++W+L +
Sbjct: 560 FLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNS 619
Query: 183 --CMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK 221
C GH + SV + Y+++GS D+ + F+ K
Sbjct: 620 GTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKK 660
Score = 81.3 bits (199), Expect = 1e-14
Identities = 47/157 (29%), Positives = 80/157 (50%), Gaps = 9/157 (5%)
Query: 549 VAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKN 608
V SPD K++A D +++ ++ K + L GH+ + +D GD +V+GS D+
Sbjct: 449 VCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRT 508
Query: 609 LKIWGLDFGDCHKSLFAHDDSVMAVKFVP-KTHYVFSVGKDRRVNYWDADK---FERLLT 664
++IW L G C +L + +D V V P Y+ + DR V WD++ ERL +
Sbjct: 509 VRIWDLRTGQCSLTL-SIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDS 567
Query: 665 LE----GHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
GH ++ + + G +V+GS DRS++ W+
Sbjct: 568 ENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWN 604
Score = 74.7 bits (182), Expect = 1e-12
Identities = 60/226 (26%), Positives = 104/226 (45%), Gaps = 34/226 (15%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSS-LI 80
++ Y SG L+S + ++ + +W +R G C+ TL+ VT++A +P I
Sbjct: 490 SLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSI-------EDGVTTVAVSPGDGKYI 542
Query: 81 AAGYGDGSIRILDSDKGTCETTLN-------GHKGAVTALRYNQAGSVLASGSKDNDVIL 133
AAG D ++R+ DS+ G L+ GHK +V ++ + + G + SGS D V L
Sbjct: 543 AAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKL 602
Query: 134 WDVVGETGLFRLR------------GHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQ 181
W++ + GH+D V V + + ++S SKD+ + WD +
Sbjct: 603 WNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSG 662
Query: 182 HCMQIVSGHHSEIWSVDV------DPGERYLVTGSADKELRFYGIK 221
+ + ++ GH + + SV V P TGS D + R + K
Sbjct: 663 NPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIWKYK 708
Score = 70.5 bits (171), Expect = 2e-11
Identities = 64/222 (28%), Positives = 102/222 (45%), Gaps = 20/222 (9%)
Query: 68 VTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSK 127
+ S+ +P +A G D IRI D + L GH+ + +L Y +G L SGS
Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505
Query: 128 DNDVILWDVVGETGLFRLR-GHRDQVTDV-VFLSSGKKLVSSSKDKFLRVWDLDTQHCMQ 185
D V +WD+ TG L D VT V V GK + + S D+ +RVWD +T ++
Sbjct: 506 DRTVRIWDL--RTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVE 563
Query: 186 IV-------SGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK--HDSVDGASVNGG--D 234
+ +GH ++SV + +V+GS D+ ++ + ++ ++ D + N G +
Sbjct: 564 RLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCE 623
Query: 235 DSSVSSKWDVLRLFGE-----IQRQSKDRVATVQFNKSGNLL 271
+ + K VL + I SKDR KSGN L
Sbjct: 624 VTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPL 665
Score = 70.1 bits (170), Expect = 3e-11
Identities = 47/177 (26%), Positives = 85/177 (47%), Gaps = 18/177 (10%)
Query: 110 VTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSK 169
+ ++ ++ G LA+G++D + +WD+ + L+GH + + + SG KLVS S
Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505
Query: 170 DKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGE-RYLVTGSADKELRFYGIKHDSVDGA 228
D+ +R+WDL T C +S + +V V PG+ +Y+ GS D+ +R + DS G
Sbjct: 506 DRTVRIWDLRTGQCSLTLS-IEDGVTTVAVSPGDGKYIAAGSLDRAVRVW----DSETGF 560
Query: 229 SVNGGDDSSVSSKWDVLRLFGEIQRQSKDRVATVQFNKSGNLLACQVAGKTVEIYRV 285
V D + S KD V +V F + G + ++V+++ +
Sbjct: 561 LVERLDSENESG------------TGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNL 605
Score = 52.0 bits (123), Expect = 7e-06
Identities = 39/135 (28%), Positives = 60/135 (43%), Gaps = 21/135 (15%)
Query: 407 GHRSDVRSVTLSSDNSFLLSTS-HNAVKIWN------------PTTGSCLRTI--DSGYG 451
GH+ V SV + D ++S S +VK+WN P +G+C T +
Sbjct: 574 GHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFV 633
Query: 452 LCSLVLPTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAAL------PDKNSF 505
L ++Y L G+KD + D SG L ++ H S+ S+A P+ N F
Sbjct: 634 LSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVF 693
Query: 506 VTGSADHDVKFWEYQ 520
TGS D + W+Y+
Sbjct: 694 ATGSGDCKARIWKYK 708
Score = 51.6 bits (122), Expect = 1e-05
Identities = 23/68 (33%), Positives = 40/68 (58%)
Query: 630 VMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSH 689
+ +V F P ++ + +DR + WD + + ++ L+GH DI+ L GD +V+GS
Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505
Query: 690 DRSIRRWD 697
DR++R WD
Sbjct: 506 DRTVRIWD 513
>TUP1_KLULA (P56094) Transcriptional repressor TUP1
Length = 682
Score = 102 bits (255), Expect = 4e-21
Identities = 98/400 (24%), Positives = 165/400 (40%), Gaps = 44/400 (11%)
Query: 340 NPTITVPDVFKLLHTIRASKKICSISFCPSTPKNSLAGLALSLN-NNLLEFYSIQSSETN 398
NP + +L ++ S +C + F S G L+ N + Y + + E
Sbjct: 303 NPALPTDLDVELHKSLEHSSVVCCVRF-------SSDGEFLATGCNKTTQVYKVSTGELV 355
Query: 399 KTLAIDLQGH-RSDVRSVTLSSDNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGLCSLVL 457
L+ D + ++ T++++ S S +A + S T S + S+
Sbjct: 356 ARLSDDSASQPQPQPQNQTVTAETSTSNSNGSSA-EDGTGNQNSAASTASSDLYIRSVCF 414
Query: 458 -PTNKYGLVGTKDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKF 516
P K+ G +D I I D+ + + ++ H + S+ P N V+GS D V+
Sbjct: 415 SPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRI 474
Query: 517 WEYQIKQKPGQATKQLAVSNVRTMKMNDDVLVVAISP-DAKYIAVALLDSTVKVHFVDTF 575
W+ T L T+ + D V VA+SP + K+IA LD TV+V DT
Sbjct: 475 WDLTT------GTCSL------TLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTG 522
Query: 576 KFFLSL-------YGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLD-------FGDCHK 621
L GH+ V + + DG +V+GS D+++K+W L+ +C
Sbjct: 523 FLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEV 582
Query: 622 SLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISN-- 679
+ H D V++V Y+ S KDR V +WD LL L+GH + + ++N
Sbjct: 583 TYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTVANGH 642
Query: 680 ----RGDFIVTGSHDRSIRRWDRTEEQFFLEEEKEKRLEE 715
TGS D R W +++ + K ++E
Sbjct: 643 PLGPEYGVFATGSGDCKARIWKYSKKNSQQNSTQIKEIKE 682
Score = 92.0 bits (227), Expect = 6e-18
Identities = 64/216 (29%), Positives = 100/216 (45%), Gaps = 25/216 (11%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
++ + GK L + A +K I +W + TL +G + S+ PS + +
Sbjct: 411 SVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTL------KGHEQDIYSLDYFPSGNKLV 464
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+G GD ++RI D GTC TL+ G T G +A+GS D V +WD +TG
Sbjct: 465 SGSGDRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWD--SDTG 522
Query: 142 LFRLR---------GHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLD-------TQHCMQ 185
R GHRD V VVF GK +VS S D+ +++W+L+ C
Sbjct: 523 FLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEV 582
Query: 186 IVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK 221
+GH + SV + Y+++GS D+ + F+ K
Sbjct: 583 TYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTK 618
Score = 79.0 bits (193), Expect = 6e-14
Identities = 60/218 (27%), Positives = 104/218 (47%), Gaps = 29/218 (13%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSS-LI 80
++ Y SG L+S + ++ + +W + G C+ TL+ VT++A +P I
Sbjct: 453 SLDYFPSGNKLVSGSGDRTVRIWDLTTGTCSLTLSI-------EDGVTTVAVSPGEGKFI 505
Query: 81 AAGYGDGSIRILDSDKGTCETTLN-------GHKGAVTALRYNQAGSVLASGSKDNDVIL 133
AAG D ++R+ DSD G L+ GH+ +V ++ + + G + SGS D V L
Sbjct: 506 AAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKL 565
Query: 134 WDVVGETGL-------FRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCMQI 186
W++ G +G GH+D V V + + ++S SKD+ + WD + + + +
Sbjct: 566 WNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGNPLLM 625
Query: 187 VSGHHSEIWSVDV------DPGERYLVTGSADKELRFY 218
+ GH + + SV V P TGS D + R +
Sbjct: 626 LQGHRNSVISVTVANGHPLGPEYGVFATGSGDCKARIW 663
Score = 75.9 bits (185), Expect = 5e-13
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 15/217 (6%)
Query: 68 VTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSK 127
+ S+ +P +A G D IRI D + TL GH+ + +L Y +G+ L SGS
Sbjct: 409 IRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSG 468
Query: 128 DNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQHCM--- 184
D V +WD+ T L T V GK + + S D+ +RVWD DT +
Sbjct: 469 DRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERL 528
Query: 185 ----QIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKHDSVDGASVNGGDDSSVSS 240
++ +GH ++SV + +V+GS D+ ++ + + + + G + + + +
Sbjct: 529 DSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNL--NGLSGQKSHAECEVTYTG 586
Query: 241 KWDVLRLFGEIQRQ------SKDRVATVQFNKSGNLL 271
D + Q SKDR KSGN L
Sbjct: 587 HKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGNPL 623
Score = 56.2 bits (134), Expect = 4e-07
Identities = 44/172 (25%), Positives = 72/172 (41%), Gaps = 17/172 (9%)
Query: 30 GKHLLSPALEK-IAVWHVRQGICTKTLTPPPP-SRGPSPAVTSIASTPSSSLIAAGYGDG 87
GK + + +L++ + VW G + L G +V S+ T + +G D
Sbjct: 502 GKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDR 561
Query: 88 SIRILD-------SDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGET 140
S+++ + CE T GHK V ++ Q + SGSKD V+ WD
Sbjct: 562 SVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGN 621
Query: 141 GLFRLRGHRDQVTDVVFLSSGKKL-------VSSSKDKFLRVWDLDTQHCMQ 185
L L+GHR+ V V +++G L + S D R+W ++ Q
Sbjct: 622 PLLMLQGHRNSVISVT-VANGHPLGPEYGVFATGSGDCKARIWKYSKKNSQQ 672
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB
alpha subunit (PAF acetylhydrolase 45 kDa subunit)
(PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
(Lissencephaly-1 protein) (LIS-1)
Length = 409
Score = 102 bits (255), Expect = 4e-21
Identities = 80/318 (25%), Positives = 135/318 (42%), Gaps = 38/318 (11%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHNA-VKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYG 463
L GHRS V V S ++S S +A +K+W+ TG RT+ + +
Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 162
Query: 464 LVGT--KDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
L+ + D TI++ D C+ + H ++ S+A +P+ + V+ S D +K WE Q
Sbjct: 163 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222
Query: 522 KQKPGQATKQLAVSN--VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFL 579
G K VR ++ N D ++A + D TV+V V T +
Sbjct: 223 ----GYCVKTFTGHREWVRMVRPNQDGTLIASCSN---------DQTVRVWVVATKECKA 269
Query: 580 SLYGHKLPVLCMDISSD--------------------GDLIVTGSADKNLKIWGLDFGDC 619
L H+ V C+ + + G +++GS DK +K+W + G C
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC 329
Query: 620 HKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISN 679
+L HD+ V V F ++ S D+ + WD + TL H + L
Sbjct: 330 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 389
Query: 680 RGDFIVTGSHDRSIRRWD 697
++VTGS D++++ W+
Sbjct: 390 TAPYVVTGSVDQTVKVWE 407
Score = 95.9 bits (237), Expect = 4e-19
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 27/218 (12%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
S++ +G H++S + +K I +W V+ G C KT T G V + +LI
Sbjct: 195 SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT------GHREWVRMVRPNQDGTLI 248
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRY--------------------NQAGS 120
A+ D ++R+ C+ L H+ V + + + G
Sbjct: 249 ASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308
Query: 121 VLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDT 180
L SGS+D + +WDV L L GH + V V+F S GK ++S + DK LRVWD
Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Query: 181 QHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+ CM+ ++ H + S+D Y+VTGS D+ ++ +
Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406
Score = 89.4 bits (220), Expect = 4e-17
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 53 KTLTPPPPSR----GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKG 108
K P PP + G VT + P S++ + D +I++ D + G E TL GH
Sbjct: 91 KEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD 150
Query: 109 AVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSS 168
+V + ++ +G +LAS S D + LWD G + + GH V+ V + +G +VS+S
Sbjct: 151 SVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 210
Query: 169 KDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+DK +++W++ T +C++ +GH + V + + + S D+ +R +
Sbjct: 211 RDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 260
Score = 83.6 bits (205), Expect = 2e-15
Identities = 61/221 (27%), Positives = 105/221 (46%), Gaps = 27/221 (12%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
+I++D SGK L S + + I +W + C +T+ G V+S+A P+ I
Sbjct: 154 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTM------HGHDHNVSSVAIMPNGDHIV 207
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+ D +I++ + G C T GH+ V +R NQ G+++AS S D V +W V +
Sbjct: 208 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 267
Query: 142 LFRLRGHRDQVTDVVFL-----------------SSGKK---LVSSSKDKFLRVWDLDTQ 181
LR H V + + SGK L+S S+DK +++WD+ T
Sbjct: 268 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 327
Query: 182 HCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKH 222
C+ + GH + + V G +++++ + DK LR + K+
Sbjct: 328 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Score = 75.5 bits (184), Expect = 6e-13
Identities = 37/118 (31%), Positives = 61/118 (51%)
Query: 580 SLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKT 639
+L GH+ PV + ++V+ S D +K+W + GD ++L H DSV + F
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161
Query: 640 HYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D + WD FE + T+ GH ++ +AI GD IV+ S D++I+ W+
Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219
Score = 71.2 bits (173), Expect = 1e-11
Identities = 55/234 (23%), Positives = 93/234 (39%), Gaps = 33/234 (14%)
Query: 485 AIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMK-MN 543
A+ H + + P + V+ S D +K W+Y+ RT+K
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFE------------RTLKGHT 149
Query: 544 DDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTG 603
D V ++ K +A D T+K+ F+ +++GH V + I +GD IV+
Sbjct: 150 DSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSA 209
Query: 604 SADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLL 663
S DK +K+W + G C K+ H + V V+ + S D+ V W E
Sbjct: 210 SRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKA 269
Query: 664 TLEGHHADIWCLA--------------------ISNRGDFIVTGSHDRSIRRWD 697
L H + C++ G F+++GS D++I+ WD
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD 323
Score = 50.1 bits (118), Expect = 3e-05
Identities = 26/98 (26%), Positives = 48/98 (48%)
Query: 80 IAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE 139
+ +G D +I++ D G C TL GH V + ++ G + S + D + +WD +
Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369
Query: 140 TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWD 177
+ L H VT + F + +V+ S D+ ++VW+
Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB
alpha subunit (PAF acetylhydrolase 45 kDa subunit)
(PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
(Lissencephaly-1 protein) (LIS-1)
Length = 409
Score = 102 bits (255), Expect = 4e-21
Identities = 80/318 (25%), Positives = 135/318 (42%), Gaps = 38/318 (11%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHNA-VKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYG 463
L GHRS V V S ++S S +A +K+W+ TG RT+ + +
Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 162
Query: 464 LVGT--KDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
L+ + D TI++ D C+ + H ++ S+A +P+ + V+ S D +K WE Q
Sbjct: 163 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222
Query: 522 KQKPGQATKQLAVSN--VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFL 579
G K VR ++ N D ++A + D TV+V V T +
Sbjct: 223 ----GYCVKTFTGHREWVRMVRPNQDGTLIASCSN---------DQTVRVWVVATKECKA 269
Query: 580 SLYGHKLPVLCMDISSD--------------------GDLIVTGSADKNLKIWGLDFGDC 619
L H+ V C+ + + G +++GS DK +K+W + G C
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC 329
Query: 620 HKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISN 679
+L HD+ V V F ++ S D+ + WD + TL H + L
Sbjct: 330 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 389
Query: 680 RGDFIVTGSHDRSIRRWD 697
++VTGS D++++ W+
Sbjct: 390 TAPYVVTGSVDQTVKVWE 407
Score = 95.9 bits (237), Expect = 4e-19
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 27/218 (12%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
S++ +G H++S + +K I +W V+ G C KT T G V + +LI
Sbjct: 195 SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT------GHREWVRMVRPNQDGTLI 248
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRY--------------------NQAGS 120
A+ D ++R+ C+ L H+ V + + + G
Sbjct: 249 ASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308
Query: 121 VLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDT 180
L SGS+D + +WDV L L GH + V V+F S GK ++S + DK LRVWD
Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Query: 181 QHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+ CM+ ++ H + S+D Y+VTGS D+ ++ +
Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406
Score = 89.4 bits (220), Expect = 4e-17
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 53 KTLTPPPPSR----GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKG 108
K P PP + G VT + P S++ + D +I++ D + G E TL GH
Sbjct: 91 KEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD 150
Query: 109 AVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSS 168
+V + ++ +G +LAS S D + LWD G + + GH V+ V + +G +VS+S
Sbjct: 151 SVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 210
Query: 169 KDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+DK +++W++ T +C++ +GH + V + + + S D+ +R +
Sbjct: 211 RDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 260
Score = 83.6 bits (205), Expect = 2e-15
Identities = 61/221 (27%), Positives = 105/221 (46%), Gaps = 27/221 (12%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
+I++D SGK L S + + I +W + C +T+ G V+S+A P+ I
Sbjct: 154 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTM------HGHDHNVSSVAIMPNGDHIV 207
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+ D +I++ + G C T GH+ V +R NQ G+++AS S D V +W V +
Sbjct: 208 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 267
Query: 142 LFRLRGHRDQVTDVVFL-----------------SSGKK---LVSSSKDKFLRVWDLDTQ 181
LR H V + + SGK L+S S+DK +++WD+ T
Sbjct: 268 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 327
Query: 182 HCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKH 222
C+ + GH + + V G +++++ + DK LR + K+
Sbjct: 328 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Score = 75.5 bits (184), Expect = 6e-13
Identities = 37/118 (31%), Positives = 61/118 (51%)
Query: 580 SLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKT 639
+L GH+ PV + ++V+ S D +K+W + GD ++L H DSV + F
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161
Query: 640 HYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D + WD FE + T+ GH ++ +AI GD IV+ S D++I+ W+
Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219
Score = 71.2 bits (173), Expect = 1e-11
Identities = 55/234 (23%), Positives = 93/234 (39%), Gaps = 33/234 (14%)
Query: 485 AIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMK-MN 543
A+ H + + P + V+ S D +K W+Y+ RT+K
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFE------------RTLKGHT 149
Query: 544 DDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTG 603
D V ++ K +A D T+K+ F+ +++GH V + I +GD IV+
Sbjct: 150 DSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSA 209
Query: 604 SADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLL 663
S DK +K+W + G C K+ H + V V+ + S D+ V W E
Sbjct: 210 SRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKA 269
Query: 664 TLEGHHADIWCLA--------------------ISNRGDFIVTGSHDRSIRRWD 697
L H + C++ G F+++GS D++I+ WD
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD 323
Score = 50.1 bits (118), Expect = 3e-05
Identities = 26/98 (26%), Positives = 48/98 (48%)
Query: 80 IAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE 139
+ +G D +I++ D G C TL GH V + ++ G + S + D + +WD +
Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369
Query: 140 TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWD 177
+ L H VT + F + +V+ S D+ ++VW+
Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB
alpha subunit (PAF acetylhydrolase 45 kDa subunit)
(PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
(Lissencephaly-1 protein) (LIS-1)
Length = 409
Score = 102 bits (255), Expect = 4e-21
Identities = 80/318 (25%), Positives = 135/318 (42%), Gaps = 38/318 (11%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHNA-VKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYG 463
L GHRS V V S ++S S +A +K+W+ TG RT+ + +
Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 162
Query: 464 LVGT--KDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
L+ + D TI++ D C+ + H ++ S+A +P+ + V+ S D +K WE Q
Sbjct: 163 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222
Query: 522 KQKPGQATKQLAVSN--VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFL 579
G K VR ++ N D ++A + D TV+V V T +
Sbjct: 223 ----GYCVKTFTGHREWVRMVRPNQDGTLIASCSN---------DQTVRVWVVATKECKA 269
Query: 580 SLYGHKLPVLCMDISSD--------------------GDLIVTGSADKNLKIWGLDFGDC 619
L H+ V C+ + + G +++GS DK +K+W + G C
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC 329
Query: 620 HKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISN 679
+L HD+ V V F ++ S D+ + WD + TL H + L
Sbjct: 330 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 389
Query: 680 RGDFIVTGSHDRSIRRWD 697
++VTGS D++++ W+
Sbjct: 390 TAPYVVTGSVDQTVKVWE 407
Score = 95.9 bits (237), Expect = 4e-19
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 27/218 (12%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
S++ +G H++S + +K I +W V+ G C KT T G V + +LI
Sbjct: 195 SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT------GHREWVRMVRPNQDGTLI 248
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRY--------------------NQAGS 120
A+ D ++R+ C+ L H+ V + + + G
Sbjct: 249 ASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308
Query: 121 VLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDT 180
L SGS+D + +WDV L L GH + V V+F S GK ++S + DK LRVWD
Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Query: 181 QHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+ CM+ ++ H + S+D Y+VTGS D+ ++ +
Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406
Score = 89.4 bits (220), Expect = 4e-17
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 53 KTLTPPPPSR----GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKG 108
K P PP + G VT + P S++ + D +I++ D + G E TL GH
Sbjct: 91 KEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD 150
Query: 109 AVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSS 168
+V + ++ +G +LAS S D + LWD G + + GH V+ V + +G +VS+S
Sbjct: 151 SVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 210
Query: 169 KDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+DK +++W++ T +C++ +GH + V + + + S D+ +R +
Sbjct: 211 RDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 260
Score = 83.6 bits (205), Expect = 2e-15
Identities = 61/221 (27%), Positives = 105/221 (46%), Gaps = 27/221 (12%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
+I++D SGK L S + + I +W + C +T+ G V+S+A P+ I
Sbjct: 154 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTM------HGHDHNVSSVAIMPNGDHIV 207
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+ D +I++ + G C T GH+ V +R NQ G+++AS S D V +W V +
Sbjct: 208 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 267
Query: 142 LFRLRGHRDQVTDVVFL-----------------SSGKK---LVSSSKDKFLRVWDLDTQ 181
LR H V + + SGK L+S S+DK +++WD+ T
Sbjct: 268 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 327
Query: 182 HCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKH 222
C+ + GH + + V G +++++ + DK LR + K+
Sbjct: 328 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Score = 75.5 bits (184), Expect = 6e-13
Identities = 37/118 (31%), Positives = 61/118 (51%)
Query: 580 SLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKT 639
+L GH+ PV + ++V+ S D +K+W + GD ++L H DSV + F
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161
Query: 640 HYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D + WD FE + T+ GH ++ +AI GD IV+ S D++I+ W+
Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219
Score = 71.2 bits (173), Expect = 1e-11
Identities = 55/234 (23%), Positives = 93/234 (39%), Gaps = 33/234 (14%)
Query: 485 AIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVRTMK-MN 543
A+ H + + P + V+ S D +K W+Y+ RT+K
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFE------------RTLKGHT 149
Query: 544 DDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTG 603
D V ++ K +A D T+K+ F+ +++GH V + I +GD IV+
Sbjct: 150 DSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSA 209
Query: 604 SADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLL 663
S DK +K+W + G C K+ H + V V+ + S D+ V W E
Sbjct: 210 SRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKA 269
Query: 664 TLEGHHADIWCLA--------------------ISNRGDFIVTGSHDRSIRRWD 697
L H + C++ G F+++GS D++I+ WD
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD 323
Score = 50.1 bits (118), Expect = 3e-05
Identities = 26/98 (26%), Positives = 48/98 (48%)
Query: 80 IAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE 139
+ +G D +I++ D G C TL GH V + ++ G + S + D + +WD +
Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369
Query: 140 TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWD 177
+ L H VT + F + +V+ S D+ ++VW+
Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB
alpha subunit (PAF acetylhydrolase 45 kDa subunit)
(PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
(Lissencephaly-1 protein) (LIS-1)
Length = 409
Score = 102 bits (255), Expect = 4e-21
Identities = 80/318 (25%), Positives = 135/318 (42%), Gaps = 38/318 (11%)
Query: 405 LQGHRSDVRSVTLSSDNSFLLSTSHNA-VKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYG 463
L GHRS V V S ++S S +A +K+W+ TG RT+ + +
Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSGK 162
Query: 464 LVGT--KDGTIEIIDIGSGTCLEAIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQI 521
L+ + D TI++ D C+ + H ++ S+A +P+ + V+ S D +K WE Q
Sbjct: 163 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222
Query: 522 KQKPGQATKQLAVSN--VRTMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFL 579
G K VR ++ N D ++A + D TV+V V T +
Sbjct: 223 ----GYCVKTFTGHREWVRMVRPNQDGTLIASCSN---------DQTVRVWVVATKECKA 269
Query: 580 SLYGHKLPVLCMDISSD--------------------GDLIVTGSADKNLKIWGLDFGDC 619
L H+ V C+ + + G +++GS DK +K+W + G C
Sbjct: 270 ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC 329
Query: 620 HKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISN 679
+L HD+ V V F ++ S D+ + WD + TL H + L
Sbjct: 330 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 389
Query: 680 RGDFIVTGSHDRSIRRWD 697
++VTGS D++++ W+
Sbjct: 390 TAPYVVTGSVDQTVKVWE 407
Score = 95.9 bits (237), Expect = 4e-19
Identities = 62/218 (28%), Positives = 101/218 (45%), Gaps = 27/218 (12%)
Query: 22 SNITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLI 80
S++ +G H++S + +K I +W V+ G C KT T G V + +LI
Sbjct: 195 SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT------GHREWVRMVRPNQDGTLI 248
Query: 81 AAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRY--------------------NQAGS 120
A+ D ++R+ C+ L H+ V + + + G
Sbjct: 249 ASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308
Query: 121 VLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDT 180
L SGS+D + +WDV L L GH + V V+F S GK ++S + DK LRVWD
Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Query: 181 QHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+ CM+ ++ H + S+D Y+VTGS D+ ++ +
Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406
Score = 89.4 bits (220), Expect = 4e-17
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 53 KTLTPPPPSR----GPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCETTLNGHKG 108
K P PP + G VT + P S++ + D +I++ D + G E TL GH
Sbjct: 91 KEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD 150
Query: 109 AVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLRGHRDQVTDVVFLSSGKKLVSSS 168
+V + ++ +G +LAS S D + LWD G + + GH V+ V + +G +VS+S
Sbjct: 151 SVEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 210
Query: 169 KDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFY 218
+DK +++W++ T +C++ +GH + V + + + S D+ +R +
Sbjct: 211 RDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 260
Score = 83.6 bits (205), Expect = 2e-15
Identities = 61/221 (27%), Positives = 105/221 (46%), Gaps = 27/221 (12%)
Query: 23 NITYDSSGKHLLSPALEK-IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIA 81
+I++D SGK L S + + I +W + C +T+ G V+S+A P+ I
Sbjct: 154 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTM------HGHDHNVSSVAIMPNGDHIV 207
Query: 82 AGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETG 141
+ D +I++ + G C T GH+ V +R NQ G+++AS S D V +W V +
Sbjct: 208 SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 267
Query: 142 LFRLRGHRDQVTDVVFL-----------------SSGKK---LVSSSKDKFLRVWDLDTQ 181
LR H V + + SGK L+S S+DK +++WD+ T
Sbjct: 268 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 327
Query: 182 HCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIKH 222
C+ + GH + + V G +++++ + DK LR + K+
Sbjct: 328 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368
Score = 74.7 bits (182), Expect = 1e-12
Identities = 37/118 (31%), Positives = 61/118 (51%)
Query: 580 SLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKT 639
+L GH+ PV + ++V+ S D +K+W + GD ++L H DSV + F
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSG 161
Query: 640 HYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVTGSHDRSIRRWD 697
+ S D + WD FE + T+ GH ++ +AI GD IV+ S D++I+ W+
Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219
Score = 71.2 bits (173), Expect = 1e-11
Identities = 66/296 (22%), Positives = 116/296 (38%), Gaps = 55/296 (18%)
Query: 485 AIEAHGGSLRSIAALPDKNSFVTGSADHDVKFWEYQIKQ---------------KPGQAT 529
A+ H + + P + V+ S D +K W+Y+ +
Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSG 161
Query: 530 KQLAVSN---------------VRTMKMND-DVLVVAISPDAKYIAVALLDSTVKVHFVD 573
K LA + +RTM +D +V VAI P+ +I A D T+K+ V
Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 221
Query: 574 TFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAV 633
T + GH+ V + + DG LI + S D+ +++W + +C L H+ V +
Sbjct: 222 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281
Query: 634 KFVPKTHY--------------------VFSVGKDRRVNYWDADKFERLLTLEGHHADIW 673
+ P++ Y + S +D+ + WD L+TL GH +
Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341
Query: 674 CLAISNRGDFIVTGSHDRSIRRWDRTEEQFFLEEEKEKRLEEKFEADLDYTSENKY 729
+ + G FI++ + D+++R WD ++ K E F LD+ Y
Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCM----KTLNAHEHFVTSLDFHKTAPY 393
Score = 50.1 bits (118), Expect = 3e-05
Identities = 26/98 (26%), Positives = 48/98 (48%)
Query: 80 IAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE 139
+ +G D +I++ D G C TL GH V + ++ G + S + D + +WD +
Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369
Query: 140 TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWD 177
+ L H VT + F + +V+ S D+ ++VW+
Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LI23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell
lineage protein 23)
Length = 665
Score = 99.8 bits (247), Expect = 3e-20
Identities = 98/383 (25%), Positives = 160/383 (41%), Gaps = 53/383 (13%)
Query: 420 DNSFLLSTSHNAVKIWNPTTGSCLRTIDSGYGLCSLVLPTNKYGLVGTKDGTIEIIDIGS 479
D+ + N +KIW+ SC R + G + N+ + G+ D T+ + D+ +
Sbjct: 232 DDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVET 291
Query: 480 GTCLEAIEAHGGSLRSIAALPDKNS-FVTGSADHDVKFWEYQIKQKPGQATKQLAVSNVR 538
G C++ + H ++ L N VT S D + W+ P T +R
Sbjct: 292 GECIKTLIHH---CEAVLHLRFANGIMVTCSKDRSIAVWD---MVSPRDIT-------IR 338
Query: 539 TMKMNDDVLVVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGD 598
+ + V + D +YI A D T+KV +DT +F +L GH+ + C+ G
Sbjct: 339 RVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYR--GR 396
Query: 599 LIVTGSADKNLKIWGLDFGDCHKSLFAHDDSVMAVKFVPKTHYVFSVGKDRRVNYWDADK 658
L+V+GS+D +++W + G C + L H++ V ++F K + S D ++ WD
Sbjct: 397 LVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKR--IVSGAYDGKIKVWD--- 451
Query: 659 FERLLTLEGHHADI-WCLAISNRG--------DF-IVTGSHDRSIRRWDRTEEQFFLEEE 708
+ L ++I C + + G DF IV+ SHD +I WD FL+
Sbjct: 452 LQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWD------FLDAP 505
Query: 709 KEKRLEEKFEADLDYTSENKYAPKEEIPEEGAVALAGKKTEETLTATDLIIERLD--IAE 766
S A E+P + AVA A E A IER D + E
Sbjct: 506 PS-----------GLPSSTNRATLPELPNQAAVARAQMLFE---MAARREIERRDREVVE 551
Query: 767 AEDKRIAEHQEEKNNINIAAFQA 789
R + ++N +IAA A
Sbjct: 552 EPALRPRANAARRHNADIAAAAA 574
Score = 73.6 bits (179), Expect = 2e-12
Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 45/191 (23%)
Query: 548 VVAISPDAKYIAVALLDSTVKVHFVDTFKFFLSLYGHKLPVLCMDISSDGDLIVTGSADK 607
V + D I L D+T+K+ + L GH VLC+ D +I++GS+D
Sbjct: 225 VYCLQYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDA 282
Query: 608 NLKIWGLDFGDCHKSLFAHDDSVMAVKFV--------------------PK--------- 638
+++W ++ G+C K+L H ++V+ ++F P+
Sbjct: 283 TVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLV 342
Query: 639 ------------THYVFSVGKDRRVNYWDADKFERLLTLEGHHADIWCLAISNRGDFIVT 686
Y+ S DR + W D E + TL GH I CL RG +V+
Sbjct: 343 GHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACL--QYRGRLVVS 400
Query: 687 GSHDRSIRRWD 697
GS D +IR WD
Sbjct: 401 GSSDNTIRLWD 411
Score = 72.0 bits (175), Expect = 7e-12
Identities = 57/210 (27%), Positives = 103/210 (48%), Gaps = 18/210 (8%)
Query: 41 IAVWHVRQGICTKTLTPPPPSRGPSPAVTSIASTPSSSLIAAGYGDGSIRILDSDKGTCE 100
I +W + C++ L+ G + +V + + +I +G D ++R+ D + G C
Sbjct: 244 IKIWDRKDYSCSRILS------GHTGSVLCLQY--DNRVIISGSSDATVRVWDVETGECI 295
Query: 101 TTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGETGLFRLR---GHRDQVTDVVF 157
TL H AV LR+ A ++ + SKD + +WD+V + R GHR V V F
Sbjct: 296 KTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDF 353
Query: 158 LSSGKKLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRF 217
+ +VS+S D+ ++VW +DT ++ ++GH I + R +V+GS+D +R
Sbjct: 354 --DDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQY--RGRLVVSGSSDNTIRL 409
Query: 218 YGIKHDSVDGASVNGGDDSSVSSKWDVLRL 247
+ I H V + G ++ ++D R+
Sbjct: 410 WDI-HSGVCLRVLEGHEELVRCIRFDEKRI 438
Score = 68.6 bits (166), Expect = 8e-11
Identities = 44/144 (30%), Positives = 77/144 (52%), Gaps = 9/144 (6%)
Query: 80 IAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVGE 139
I +G D +I+I D +C L+GH G+V L+Y+ V+ SGS D V +WDV
Sbjct: 235 IVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYD--NRVIISGSSDATVRVWDVETG 292
Query: 140 TGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWDLDTQH---CMQIVSGHHSEIWS 196
+ L H + V + F + +V+ SKD+ + VWD+ + +++ GH + +
Sbjct: 293 ECIKTLIHHCEAVLHLRFANG--IMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNV 350
Query: 197 VDVDPGERYLVTGSADKELRFYGI 220
VD D +RY+V+ S D+ ++ + +
Sbjct: 351 VDFD--DRYIVSASGDRTIKVWSM 372
Score = 46.2 bits (108), Expect = 4e-04
Identities = 32/108 (29%), Positives = 51/108 (46%), Gaps = 13/108 (12%)
Query: 79 LIAAGYGDGSIRILDSDKGTCETTLNGHKGAVTALRYNQAGSVLASGSKDNDVILWDVVG 138
L+ +G D +IR+ D G C L GH+ V +R+++ V SG+ D + +WD+
Sbjct: 397 LVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIV--SGAYDGKIKVWDLQA 454
Query: 139 ---------ETGLFRLRGHRDQVTDVVFLSSGKKLVSSSKDKFLRVWD 177
E L L H +V + F ++VSSS D + +WD
Sbjct: 455 ALDPRALSSEICLCSLVQHTGRVFRLQF--DDFQIVSSSHDDTILIWD 500
Score = 41.2 bits (95), Expect = 0.013
Identities = 17/59 (28%), Positives = 34/59 (56%), Gaps = 2/59 (3%)
Query: 163 KLVSSSKDKFLRVWDLDTQHCMQIVSGHHSEIWSVDVDPGERYLVTGSADKELRFYGIK 221
K+VS +D +++WD C +I+SGH + + D R +++GS+D +R + ++
Sbjct: 234 KIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYD--NRVIISGSSDATVRVWDVE 290
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.315 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,153,955
Number of Sequences: 164201
Number of extensions: 4906939
Number of successful extensions: 27856
Number of sequences better than 10.0: 533
Number of HSP's better than 10.0 without gapping: 377
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 19321
Number of HSP's gapped (non-prelim): 4188
length of query: 943
length of database: 59,974,054
effective HSP length: 120
effective length of query: 823
effective length of database: 40,269,934
effective search space: 33142155682
effective search space used: 33142155682
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)
Lotus: description of TM0012c.1