BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0010.2
(370 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ROR_HUMAN (O43390) Heterogeneous nuclear ribonucleoprotein R (hn... 161 3e-39
ROQ_RAT (Q7TP47) Heterogeneous nuclear ribonucleoprotein Q (hnRN... 160 5e-39
ROQ_MOUSE (Q7TMK9) Heterogeneous nuclear ribonucleoprotein Q (hn... 160 5e-39
ROQ_HUMAN (O60506) Heterogeneous nuclear ribonucleoprotein Q (hn... 158 2e-38
PAB2_ARATH (P42731) Polyadenylate-binding protein 2 (Poly(A)-bin... 99 2e-20
NUCL_XENLA (P20397) Nucleolin (Protein C23) 96 1e-19
PAB5_ARATH (Q05196) Polyadenylate-binding protein 5 (Poly(A)-bin... 95 3e-19
NUCL_CHICK (P15771) Nucleolin (Protein C23) 94 7e-19
NUCL_HUMAN (P19338) Nucleolin (Protein C23) 92 3e-18
NUCL_MESAU (P08199) Nucleolin (Protein C23) 91 5e-18
NUCL_RAT (P13383) Nucleolin (Protein C23) 90 1e-17
PABP_YEAST (P04147) Polyadenylate-binding protein, cytoplasmic a... 87 9e-17
PAB4_HUMAN (Q13310) Polyadenylate-binding protein 4 (Poly(A)-bin... 86 2e-16
NUCL_MOUSE (P09405) Nucleolin (Protein C23) 84 6e-16
PABP_SCHPO (P31209) Polyadenylate-binding protein (Poly(A)-bindi... 83 1e-15
PABX_ARATH (Q9ZQA8) Probable polyadenylate-binding protein At2g3... 82 2e-15
NSR1_YEAST (P27476) Nuclear localization sequence binding protei... 80 6e-15
PAB3_HUMAN (Q9H361) Polyadenylate-binding protein 3 (Poly(A)-bin... 80 8e-15
TIAR_HUMAN (Q01085) Nucleolysin TIAR (TIA-1 related protein) 78 3e-14
PAB1_RAT (Q9EPH8) Polyadenylate-binding protein 1 (Poly(A)-bindi... 78 3e-14
>ROR_HUMAN (O43390) Heterogeneous nuclear ribonucleoprotein R (hnRNP
R)
Length = 633
Score = 161 bits (407), Expect = 3e-39
Identities = 95/307 (30%), Positives = 165/307 (52%), Gaps = 16/307 (5%)
Query: 22 PPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELAS 81
P +EV++G I ++ E++L + G + ++R+M SG+ +GYAF+ F KE A
Sbjct: 161 PGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQ 220
Query: 82 QAIEELNNSEFK-GKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLK 140
+A++ ++ E + GK + S A +RLF+G+IPK T E++ + + V G++ + L
Sbjct: 221 EAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYH 280
Query: 141 DLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP-RNSESSAVSQV 199
+NRGF F+EY +H A +R+++ + K+ N TV WA+P + +++V
Sbjct: 281 QPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKV 340
Query: 200 KAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALK 259
K ++V+NL +T++ L+K F GK+ +V ++ + FVHF DR +A+KA+
Sbjct: 341 KVLFVRNLATTVTEEILEKSFSEFGKLERV--------KKLKDYAFVHFEDRGAAVKAMD 392
Query: 260 NTEKYEIDGKNLECSLAKP---EADQRSSGTSNSQKPVVLPTY---PHRLGYGMVGGAYG 313
EI+G+ +E LAKP + +R + S+ Y P R+ + G G
Sbjct: 393 EMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRG 452
Query: 314 GIGAGYG 320
G GYG
Sbjct: 453 GGRGGYG 459
>ROQ_RAT (Q7TP47) Heterogeneous nuclear ribonucleoprotein Q (hnRNP
Q) (hnRNP-Q) (Synaptotagmin binding, cytoplasmic RNA
interacting protein) (Liver regeneration-related protein
LRRG077) (Ab2-339)
Length = 533
Score = 160 bits (405), Expect = 5e-39
Identities = 85/272 (31%), Positives = 151/272 (55%), Gaps = 10/272 (3%)
Query: 22 PPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELAS 81
P +E+++G I ++ E++L + G + ++R+M +G +GYAFV F TKE A
Sbjct: 68 PSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQ 127
Query: 82 QAIEELNNSEFK-GKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLK 140
+A++ NN E + GK I S A +RLF+G+IPK T E + + + V G+ + L
Sbjct: 128 EAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYH 187
Query: 141 DLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP-RNSESSAVSQV 199
+NRGF F+EY +H A +R+++ + K+ N TV WA+P + + +++V
Sbjct: 188 QPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKV 247
Query: 200 KAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALK 259
K ++V+NL +T++ L+K F GK+ +V ++ + F+HF +R A+KA++
Sbjct: 248 KVLFVRNLANTVTEEILEKSFSQFGKLERV--------KKLKDYAFIHFDERDGAVKAME 299
Query: 260 NTEKYEIDGKNLECSLAKPEADQRSSGTSNSQ 291
+++G+N+E AKP +R + Q
Sbjct: 300 EMNGKDLEGENIEIVFAKPPDQKRKERKAQRQ 331
>ROQ_MOUSE (Q7TMK9) Heterogeneous nuclear ribonucleoprotein Q (hnRNP
Q) (hnRNP-Q) (Synaptotagmin binding, cytoplasmic RNA
interacting protein) (Glycine-and tyrosine-rich RNA
binding protein) (GRY-RBP) (NS1-associated protein 1)
(pp68)
Length = 623
Score = 160 bits (405), Expect = 5e-39
Identities = 85/272 (31%), Positives = 151/272 (55%), Gaps = 10/272 (3%)
Query: 22 PPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELAS 81
P +E+++G I ++ E++L + G + ++R+M +G +GYAFV F TKE A
Sbjct: 158 PSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQ 217
Query: 82 QAIEELNNSEFK-GKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLK 140
+A++ NN E + GK I S A +RLF+G+IPK T E + + + V G+ + L
Sbjct: 218 EAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYH 277
Query: 141 DLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP-RNSESSAVSQV 199
+NRGF F+EY +H A +R+++ + K+ N TV WA+P + + +++V
Sbjct: 278 QPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKV 337
Query: 200 KAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALK 259
K ++V+NL +T++ L+K F GK+ +V ++ + F+HF +R A+KA++
Sbjct: 338 KVLFVRNLANTVTEEILEKSFSQFGKLERV--------KKLKDYAFIHFDERDGAVKAME 389
Query: 260 NTEKYEIDGKNLECSLAKPEADQRSSGTSNSQ 291
+++G+N+E AKP +R + Q
Sbjct: 390 EMNGKDLEGENIEIVFAKPPDQKRKERKAQRQ 421
>ROQ_HUMAN (O60506) Heterogeneous nuclear ribonucleoprotein Q (hnRNP
Q) (hnRNP-Q) (Synaptotagmin binding, cytoplasmic RNA
interacting protein) (Glycine-and tyrosine-rich RNA
binding protein) (GRY-RBP) (NS1-associated protein 1)
Length = 623
Score = 158 bits (400), Expect = 2e-38
Identities = 84/272 (30%), Positives = 150/272 (54%), Gaps = 10/272 (3%)
Query: 22 PPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELAS 81
P +E+++G I ++ E++L + G + ++R+M +G +GYAFV F TKE A
Sbjct: 158 PSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQ 217
Query: 82 QAIEELNNSEFK-GKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLK 140
+A++ NN E + GK I S A +RLF+G+IPK T E + + + V G+ + L
Sbjct: 218 EAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYH 277
Query: 141 DLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP-RNSESSAVSQV 199
+NR F F+EY +H A +R+++ + K+ N TV WA+P + + +++V
Sbjct: 278 QPDDKKKNRSFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKV 337
Query: 200 KAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALK 259
K ++V+NL +T++ L+K F GK+ +V ++ + F+HF +R A+KA++
Sbjct: 338 KVLFVRNLANTVTEEILEKAFSQFGKLERV--------KKLKDYAFIHFDERDGAVKAME 389
Query: 260 NTEKYEIDGKNLECSLAKPEADQRSSGTSNSQ 291
+++G+N+E AKP +R + Q
Sbjct: 390 EMNGKDLEGENIEIVFAKPPDQKRKERKAQRQ 421
>PAB2_ARATH (P42731) Polyadenylate-binding protein 2
(Poly(A)-binding protein 2) (PABP 2)
Length = 629
Score = 98.6 bits (244), Expect = 2e-20
Identities = 74/271 (27%), Positives = 134/271 (49%), Gaps = 18/271 (6%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
++ +Y+G + NV++ L +G V VR+ + + GY +V F + A++AI
Sbjct: 35 NTSLYVGDLDFNVTDSQLFDAFGQMGTVVTVRVCRDLVTRRSLGYGYVNFTNPQDAARAI 94
Query: 85 EELNNSEFKGKKIKCSSS--------QAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISI 136
+ELN GK I+ S +FI N+ + + + + G ++S
Sbjct: 95 QELNYIPLYGKPIRVMYSHRDPSVRRSGAGNIFIKNLDESIDHKALHDTFSSFG-NIVSC 153
Query: 137 ELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAV 196
++ D SSG+++G+ F++Y N A+ + +K+ + L + V R S
Sbjct: 154 KVAVD--SSGQSKGYGFVQYANEESAQKAIEKL--NGMLLNDKQVYVGPFLRRQERDSTA 209
Query: 197 SQVK--AVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSR-FGFVHFSDRSS 253
++ K VYVKNL E+ T D LK F +GKIT V+ K G+ KS+ FGFV+F +
Sbjct: 210 NKTKFTNVYVKNLAESTTDDDLKNAFGEYGKITSAVV--MKDGEGKSKGFGFVNFENADD 267
Query: 254 AMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
A +A+++ ++ D K A+ ++++ +
Sbjct: 268 AARAVESLNGHKFDDKEWYVGRAQKKSERET 298
Score = 81.6 bits (200), Expect = 3e-15
Identities = 76/330 (23%), Positives = 143/330 (43%), Gaps = 32/330 (9%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
+ ++I + ++ + L S G + ++ SG+ KGY FV + +E A +AI
Sbjct: 123 AGNIFIKNLDESIDHKALHDTFSSFGNIVSCKVA-VDSSGQSKGYGFVQYANEESAQKAI 181
Query: 85 EELNNSEFKGKKI-----------KCSSSQAKH-RLFIGNIPKKWTVEDMKKVVADVGPG 132
E+LN K++ ++++ K +++ N+ + T +D+K + G
Sbjct: 182 EKLNGMLLNDKQVYVGPFLRRQERDSTANKTKFTNVYVKNLAESTTDDDLKNAFGEYGK- 240
Query: 133 VISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNF------------KLENNA 180
+ S ++KD G+++GF F+ + N A + + ++ F K E
Sbjct: 241 ITSAVVMKD--GEGKSKGFGFVNFENADDAARAVESLNGHKFDDKEWYVGRAQKKSERET 298
Query: 181 PTVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEK 240
E E++ Q +YVKNL +I+ + LK++F G +T + +G K
Sbjct: 299 ELRVRYEQNLKEAADKFQSSNLYVKNLDPSISDEKLKEIFSPFGTVTSSKVMRDPNGTSK 358
Query: 241 SRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQ--RSSGTSNSQKPVVL-P 297
GFV F+ A +A+ I+ K L ++A+ + D+ R + +PV + P
Sbjct: 359 GS-GFVAFATPEEATEAMSQLSGKMIESKPLYVAIAQRKEDRRVRLQAQFSQVRPVAMQP 417
Query: 298 TYPHRLGYGMVGGAYGGIGAGYGAAGFAQV 327
+ R+ GG G YG A A +
Sbjct: 418 SVGPRMPVYPPGGPGIGQQMFYGQAPPAMI 447
Score = 33.9 bits (76), Expect = 0.68
Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 2/114 (1%)
Query: 178 NNAPTVSWAEPRNSESSAVSQV--KAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAK 235
N + + P S + +Q ++YV +L N+T L F G + V +
Sbjct: 12 NGSTAAVTSAPATSGGATATQFGNTSLYVGDLDFNVTDSQLFDAFGQMGTVVTVRVCRDL 71
Query: 236 SGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSN 289
+ +G+V+F++ A +A++ + GK + + + R SG N
Sbjct: 72 VTRRSLGYGYVNFTNPQDAARAIQELNYIPLYGKPIRVMYSHRDPSVRRSGAGN 125
>NUCL_XENLA (P20397) Nucleolin (Protein C23)
Length = 650
Score = 95.9 bits (237), Expect = 1e-19
Identities = 88/331 (26%), Positives = 154/331 (45%), Gaps = 49/331 (14%)
Query: 7 NDEVEKKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGER 66
N E KK + S +++ I + + E+L+ ++ ++RI K+ G
Sbjct: 312 NKTAENKKERD-------SRTLFVKNIPYSTTVEELQEIFENA---KDIRIPTGKD-GSN 360
Query: 67 KGYAFVAFKTKELASQAIEELNNSEFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVV 126
KG A+V F ++ A++A+EE +E +G+ I + K + GN KK D K +V
Sbjct: 361 KGIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDFTGEKSQNS-GN--KKGPEGDSKVLV 417
Query: 127 ADVGPGVISIELLKDL----------QSSGRNRGFAFIEYYNHACAEYSRQKMSN-SNFK 175
+ + + L+++ Q+ GR +GFAFIE+ + AE ++ M + +N +
Sbjct: 418 VNNLSYSATEDSLREVFEKATSIRIPQNQGRAKGFAFIEF---SSAEDAKDAMDSCNNTE 474
Query: 176 LENNAPTVSWAE---PRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLP 232
+E + + +++ P+ +Q K ++V+ L E+ T+++LK+ F+ G + ++
Sbjct: 475 IEGRSIRLEFSQGGGPQGGGRGGSAQSKTLFVRGLSEDTTEETLKEAFD--GSVNARIVT 532
Query: 233 PAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSNSQK 292
+G K FGFV FS A A + E EIDG + AKP+ D + G
Sbjct: 533 DRDTGASKG-FGFVDFSTAEDAKAAKEAMEDGEIDGNKVTLDFAKPKGDSQRGG------ 585
Query: 293 PVVLPTYPHRLGYGMVGGAYGGIGAGYGAAG 323
R G+G GG GG G G G
Sbjct: 586 ---------RGGFGRGGGFRGGRGGRGGGGG 607
Score = 67.0 bits (162), Expect = 7e-11
Identities = 63/285 (22%), Positives = 126/285 (44%), Gaps = 39/285 (13%)
Query: 28 VYIGGIANNVSEEDLR-----VFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQ 82
++IG + + ++L+ F + + ++RI G K + +V F ++E +
Sbjct: 234 IFIGNLNSTKEFDELKDALREFFSKKNLTIQDIRI------GNSKKFGYVDFSSEEEVEK 287
Query: 83 AIEELNNSEFKGKKIKCSSSQA--------------KHRLFIGNIPKKWTVEDMKKVVAD 128
A++ L + G ++K + A LF+ NIP TVE+++++ +
Sbjct: 288 ALK-LTGKKILGTEVKIEKAMAFDKNKTAENKKERDSRTLFVKNIPYSTTVEELQEIFEN 346
Query: 129 VGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP 188
I I KD G N+G A++E+ N A + ++ + + + + +
Sbjct: 347 AKD--IRIPTGKD----GSNKGIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDFTGEKS 400
Query: 189 RNS--ESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFV 246
+NS + K + V NL + T+DSL+++FE K T + + P G+ K F F+
Sbjct: 401 QNSGNKKGPEGDSKVLVVNNLSYSATEDSLREVFE---KATSIRI-PQNQGRAKG-FAFI 455
Query: 247 HFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSNSQ 291
FS A A+ + EI+G+++ ++ Q ++Q
Sbjct: 456 EFSSAEDAKDAMDSCNNTEIEGRSIRLEFSQGGGPQGGGRGGSAQ 500
Score = 33.1 bits (74), Expect = 1.2
Identities = 20/77 (25%), Positives = 34/77 (43%), Gaps = 1/77 (1%)
Query: 187 EPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFV 246
E + +++ S+ ++++ NL D LK + + + G K +FG+V
Sbjct: 219 EAKKTKTDTASEGLSIFIGNLNSTKEFDELKDALREFFSKKNLTIQDIRIGNSK-KFGYV 277
Query: 247 HFSDRSSAMKALKNTEK 263
FS KALK T K
Sbjct: 278 DFSSEEEVEKALKLTGK 294
>PAB5_ARATH (Q05196) Polyadenylate-binding protein 5
(Poly(A)-binding protein 5) (PABP 5)
Length = 668
Score = 94.7 bits (234), Expect = 3e-19
Identities = 79/277 (28%), Positives = 133/277 (47%), Gaps = 16/277 (5%)
Query: 16 AELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFK 75
AE L P+SS +Y+G + +V+E L V V +R+ + + GYA+V F
Sbjct: 36 AEALQTHPNSS-LYVGDLDPSVNESHLLDLFNQVAPVHNLRVCRDL-THRSLGYAYVNFA 93
Query: 76 TKELASQAIEELNNSEFKGKKIKCSSSQ--------AKHRLFIGNIPKKWTVEDMKKVVA 127
E AS+A+E LN + + + I+ S K +FI N+ + + + +
Sbjct: 94 NPEDASRAMESLNYAPIRDRPIRIMLSNRDPSTRLSGKGNVFIKNLDASIDNKALYETFS 153
Query: 128 DVGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNS--NFKLENNAPTVSW 185
G ++S ++ D+ GR++G+ F+++ A+ + K++ N K V
Sbjct: 154 SFGT-ILSCKVAMDVV--GRSKGYGFVQFEKEETAQAAIDKLNGMLLNDKQVFVGHFVRR 210
Query: 186 AEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGF 245
+ SES AV VYVKNLP+ IT D LKK F +G I+ V+ +SG +S FGF
Sbjct: 211 QDRARSESGAVPSFTNVYVKNLPKEITDDELKKTFGKYGDISSAVVMKDQSGNSRS-FGF 269
Query: 246 VHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQ 282
V+F +A A++ + L A+ ++D+
Sbjct: 270 VNFVSPEAAAVAVEKMNGISLGEDVLYVGRAQKKSDR 306
Score = 79.3 bits (194), Expect = 1e-14
Identities = 71/299 (23%), Positives = 132/299 (43%), Gaps = 46/299 (15%)
Query: 64 GERKGYAFVAFKTKELASQAIEELNNSEFKGKKI--------------KCSSSQAKHRLF 109
G KGY FV F+ +E A AI++LN K++ + + + ++
Sbjct: 169 GRSKGYGFVQFEKEETAQAAIDKLNGMLLNDKQVFVGHFVRRQDRARSESGAVPSFTNVY 228
Query: 110 IGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKM 169
+ N+PK+ T +++KK G + S ++KD SG +R F F+ + + A + +KM
Sbjct: 229 VKNLPKEITDDELKKTFGKYGD-ISSAVVMKD--QSGNSRSFGFVNFVSPEAAAVAVEKM 285
Query: 170 SNSNFKLENNAPTVSWAEPRNS---------ESSAVSQVKAV-----YVKNLPENITQDS 215
+ L + V A+ ++ E +S+ + + Y+KNL +++ +
Sbjct: 286 NG--ISLGEDVLYVGRAQKKSDREEELRRKFEQERISRFEKLQGSNLYLKNLDDSVNDEK 343
Query: 216 LKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSL 275
LK++F +G +T + G + FGFV +S+ A+ A+K I K L +L
Sbjct: 344 LKEMFSEYGNVTSCKVMMNSQGLSRG-FGFVAYSNPEEALLAMKEMNGKMIGRKPLYVAL 402
Query: 276 AKPEADQ-----------RSSGTSNSQKPVVLPTYPHRLGYGMVGGAYGGIGAGYGAAG 323
A+ + ++ RS GT S P + + H G + G + + G+ G
Sbjct: 403 AQRKEERQAHLQSLFTQIRSPGTM-SPVPSPMSGFHHHPPGGPMSGPHHPMFIGHNGQG 460
Score = 38.9 bits (89), Expect = 0.021
Identities = 21/80 (26%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 26 SEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIE 85
S +Y+ + ++V++E L+ G V+ ++M + G +G+ FVA+ E A A++
Sbjct: 328 SNLYLKNLDDSVNDEKLKEMFSEYGNVTSCKVMMNSQ-GLSRGFGFVAYSNPEEALLAMK 386
Query: 86 ELNNSEFKGKKIKCSSSQAK 105
E+N K + + +Q K
Sbjct: 387 EMNGKMIGRKPLYVALAQRK 406
>NUCL_CHICK (P15771) Nucleolin (Protein C23)
Length = 694
Score = 93.6 bits (231), Expect = 7e-19
Identities = 83/319 (26%), Positives = 151/319 (47%), Gaps = 46/319 (14%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
+++ + V+E++++ ++ EVR++ KE G KG A++ FKT+ A +A+EE
Sbjct: 373 LFVKNLPYRVTEDEMKNVFENA---LEVRLVLNKE-GSSKGMAYIEFKTEAEAEKALEEK 428
Query: 88 NNSEFKGKKI--------------KCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGV 133
+E G+ + K + L + N+ + E ++++
Sbjct: 429 QGTEVDGRAMVIDYTGEKSQQESQKGGGERESKTLIVNNLSYAASEETLQELFKKA---- 484
Query: 134 ISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSN-SNFKLENNAPTVSWAEPR--- 189
SI++ ++ Q GR +G+AF+E+ AE +++ +++ +N ++E A + ++ P
Sbjct: 485 TSIKMPQNNQ--GRPKGYAFVEF---PTAEDAKEALNSCNNTEIEGRAIRLEFSSPSWQK 539
Query: 190 ---NSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFV 246
N+ Q K ++V+ L E+ T+++L++ FE G I+ ++ +G K FGFV
Sbjct: 540 GNMNARGGFNQQSKTLFVRGLSEDTTEETLRESFE--GSISARIVTDRDTGSSKG-FGFV 596
Query: 247 HFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEAD-QRSSGTSNSQKPVVLPTYPHRLGY 305
FS A A + E EIDG + AKP+ + QR G + R G
Sbjct: 597 DFSSPEDAKAAKEAMEDGEIDGNKVTLDFAKPKGEFQRGGGFGGG--------FGGRGGR 648
Query: 306 GMVGGAYGGIGAGYGAAGF 324
G GG GG G G GF
Sbjct: 649 GGRGGGRGGFGGRGGGRGF 667
Score = 58.9 bits (141), Expect = 2e-08
Identities = 43/181 (23%), Positives = 84/181 (45%), Gaps = 27/181 (14%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S + + ++ SEE L+ + + M G KGYAFV F T E A +A+
Sbjct: 460 SKTLIVNNLSYAASEETLQELFKKATSIK----MPQNNQGRPKGYAFVEFPTAEDAKEAL 515
Query: 85 EELNNSEFKGKKIKCSSS----------------QAKHRLFIGNIPKKWTVEDMKKVVAD 128
NN+E +G+ I+ S Q LF+ + + T E +++
Sbjct: 516 NSCNNTEIEGRAIRLEFSSPSWQKGNMNARGGFNQQSKTLFVRGLSEDTTEETLRESF-- 573
Query: 129 VGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP 188
G IS ++ D + +G ++GF F+++ + A+ +++ M + +++ N T+ +A+P
Sbjct: 574 --EGSISARIVTD-RDTGSSKGFGFVDFSSPEDAKAAKEAMEDG--EIDGNKVTLDFAKP 628
Query: 189 R 189
+
Sbjct: 629 K 629
Score = 54.7 bits (130), Expect = 4e-07
Identities = 46/208 (22%), Positives = 91/208 (43%), Gaps = 24/208 (11%)
Query: 85 EELNNSEFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQS 144
E N S + KK K + + LF+ N+ E+++ + + K+LQ
Sbjct: 260 EMANKSAPEAKKKKTETPASAFSLFVKNLTPTKDYEELRTAIKEFFGK-------KNLQV 312
Query: 145 S----GRNRGFAFIEYYN----HACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAV 196
S G ++ F ++++ + + + +K+ KLE S E + +
Sbjct: 313 SEVRIGSSKRFGYVDFLSAEDMDKALQLNGKKLMGLEIKLEKAKSKESLKENKKERDA-- 370
Query: 197 SQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMK 256
+ ++VKNLP +T+D +K +FE+ ++ V+ K G K ++ F + A K
Sbjct: 371 ---RTLFVKNLPYRVTEDEMKNVFENALEVRLVL---NKEGSSKG-MAYIEFKTEAEAEK 423
Query: 257 ALKNTEKYEIDGKNLECSLAKPEADQRS 284
AL+ + E+DG+ + ++ Q S
Sbjct: 424 ALEEKQGTEVDGRAMVIDYTGEKSQQES 451
>NUCL_HUMAN (P19338) Nucleolin (Protein C23)
Length = 706
Score = 91.7 bits (226), Expect = 3e-18
Identities = 74/287 (25%), Positives = 139/287 (47%), Gaps = 38/287 (13%)
Query: 51 EVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEELNNSEFKGKKIKC--SSSQAKHRL 108
+ +E+R++ + G+ KG A++ FKT+ A + EE +E G+ I + + +++
Sbjct: 414 DAAEIRLVS--KDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQD 471
Query: 109 FIGNIPKKWTVEDMKKVVADVGPGVISIELLKDL-----------QSSGRNRGFAFIEYY 157
+ G W+ E V++++ E L+++ +G+++G+AFIE+
Sbjct: 472 YRGGKNSTWSGESKTLVLSNLSYSATE-ETLQEVFEKATFIKVPQNQNGKSKGYAFIEF- 529
Query: 158 NHACAEYSRQKMSNSNFK-LENNAPTVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSL 216
A E +++ +++ N + +E A + PR S ++ K ++VK L E+ T+++L
Sbjct: 530 --ASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETL 587
Query: 217 KKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLA 276
K+ F+ G + ++ ++G K FGFV F+ A +A+ E EIDG + A
Sbjct: 588 KESFD--GSVRARIVTDRETGSSKG-FGFVDFNSEEDAKEAM---EDGEIDGNKVTLDWA 641
Query: 277 KPEADQRSSGTSNSQKPVVLPTYPHRLGYGMVGGAYGGIGAGYGAAG 323
KP+ + G R G+G GG GG G G+G G
Sbjct: 642 KPKGEGGFGGRGGG-----------RGGFGGRGGGRGGRG-GFGGRG 676
Score = 61.2 bits (147), Expect = 4e-09
Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 25/201 (12%)
Query: 75 KTKELASQAIEELNNSEFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGP--- 131
+ KE+A Q E K +K++ + LF+GN+ + ++K ++DV
Sbjct: 279 RKKEMAKQKAAP----EAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKND 334
Query: 132 -GVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRN 190
V+ + + G R F ++++ + AE + + + K+ N + +P+
Sbjct: 335 LAVVDVRI-------GMTRKFGYVDFES---AEDLEKALELTGLKVFGNE--IKLEKPKG 382
Query: 191 SESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSD 250
+S + + KNLP +TQD LK++FE +I V +K G+ K ++ F
Sbjct: 383 KDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV----SKDGKSKG-IAYIEFKT 437
Query: 251 RSSAMKALKNTEKYEIDGKNL 271
+ A K + + EIDG+++
Sbjct: 438 EADAEKTFEEKQGTEIDGRSI 458
Score = 56.6 bits (135), Expect = 1e-07
Identities = 41/175 (23%), Positives = 86/175 (48%), Gaps = 24/175 (13%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S + + ++ + +EE L Q V E + + ++G+ KGYAF+ F + E A +A+
Sbjct: 484 SKTLVLSNLSYSATEETL----QEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL 539
Query: 85 EELNNSEFKGKKIKC----------SSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVI 134
N E +G+ I+ + SQ LF+ + + T E +K+ G +
Sbjct: 540 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESF----DGSV 595
Query: 135 SIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPR 189
++ D + +G ++GF F+++ + E +++ M + +++ N T+ WA+P+
Sbjct: 596 RARIVTD-RETGSSKGFGFVDFNSE---EDAKEAMEDG--EIDGNKVTLDWAKPK 644
>NUCL_MESAU (P08199) Nucleolin (Protein C23)
Length = 713
Score = 90.9 bits (224), Expect = 5e-18
Identities = 74/300 (24%), Positives = 139/300 (45%), Gaps = 34/300 (11%)
Query: 36 NVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEELNNSEFKGK 95
N++E++L+ + + E+R++ + G+ KG A++ FK++ A + +EE +E G+
Sbjct: 403 NITEDELKEVFE---DALEIRLVS--QDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGR 457
Query: 96 KIKCSSSQAK-HRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSS--------- 145
+ + K R W+ E V++++ L + + +
Sbjct: 458 SVSLYYTGEKGQRQERTGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQ 517
Query: 146 -GRNRGFAFIEYYNHACAEYSRQKMSNSN-FKLENNAPTVSWAEPRNSESSAVSQVKAVY 203
G+++G+AFIE+ A E +++ +++ N ++E + PR S ++ K ++
Sbjct: 518 QGKSKGYAFIEF---ASFEDAKEALNSCNKMEIEGRTIRLELQGPRGSPNARSQPSKTLF 574
Query: 204 VKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEK 263
VK L E+ T+++LK+ FE G + ++ ++G K FGFV F+ A A + E
Sbjct: 575 VKGLSEDTTEETLKESFE--GSVRARIVTDRETGSSKG-FGFVDFNSEEDAKAAKEAMED 631
Query: 264 YEIDGKNLECSLAKPEADQRSSGTSNSQKPVVLPTYPHRLGYGMVGGAYGGIGAGYGAAG 323
EIDG + AKP+ + G R G+G GG GG G+G G
Sbjct: 632 GEIDGNKVTLDWAKPKGEGGFGGRGGG-----------RGGFGGRGGGRGGGRGGFGGRG 680
Score = 65.1 bits (157), Expect = 3e-10
Identities = 54/211 (25%), Positives = 103/211 (48%), Gaps = 18/211 (8%)
Query: 91 EFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRG 150
E K +K++ S S LFIGN+ +V ++K +++ P + + D+++ G NR
Sbjct: 292 EAKKQKVEGSESTTPFNLFIGNLNPNKSVAELKVAISE--PFAKNDLAVVDVRT-GTNRK 348
Query: 151 FAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVSQVKAVYVKNLPEN 210
F ++++ + AE + + + K+ N + +P+ +S V + + KNL N
Sbjct: 349 FGYVDFES---AEDLEKALELTGLKVFGNE--IKLEKPKGRDSKKVRAARTLLAKNLSFN 403
Query: 211 ITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKN 270
IT+D LK++FE +I V ++ G+ K ++ F + A K L+ + EIDG++
Sbjct: 404 ITEDELKEVFEDALEIRLV----SQDGKSKG-IAYIEFKSEADAEKNLEEKQGAEIDGRS 458
Query: 271 LECSLA-----KPEADQRSSGTSNSQKPVVL 296
+ + E ++S S K +VL
Sbjct: 459 VSLYYTGEKGQRQERTGKNSTWSGESKTLVL 489
Score = 60.5 bits (145), Expect = 7e-09
Identities = 41/175 (23%), Positives = 86/175 (48%), Gaps = 21/175 (12%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S + + ++ + +EE L Q V E + + + G+ KGYAF+ F + E A +A+
Sbjct: 484 SKTLVLSNLSYSATEETL----QEVFEKATFIKVPQNQQGKSKGYAFIEFASFEDAKEAL 539
Query: 85 EELNNSEFKGKKIKC----------SSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVI 134
N E +G+ I+ + SQ LF+ + + T E +K+ G +
Sbjct: 540 NSCNKMEIEGRTIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESF----EGSV 595
Query: 135 SIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPR 189
++ D + +G ++GF F+++ + A+ +++ M + +++ N T+ WA+P+
Sbjct: 596 RARIVTD-RETGSSKGFGFVDFNSEEDAKAAKEAMEDG--EIDGNKVTLDWAKPK 647
>NUCL_RAT (P13383) Nucleolin (Protein C23)
Length = 712
Score = 89.7 bits (221), Expect = 1e-17
Identities = 78/301 (25%), Positives = 141/301 (45%), Gaps = 37/301 (12%)
Query: 36 NVSEEDLR-VFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEELNNSEFKG 94
N++E++L+ VF +V E+R++ + G KG A++ FK++ A + +EE +E G
Sbjct: 406 NITEDELKEVFEDAV----EIRLVS--QDGRSKGIAYIEFKSEADAEKNLEEKQGAEIDG 459
Query: 95 KKIKCSSSQAK-HRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSS-------- 145
+ + + K R W+ E V++++ L + + +
Sbjct: 460 RSVSLYYTGEKGQRQERTGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQN 519
Query: 146 --GRNRGFAFIEYYNHACAEYSRQKMSNSN-FKLENNAPTVSWAEPRNSESSAVSQVKAV 202
G+++G+AFIE+ A E +++ +++ N ++E + PR S ++ K +
Sbjct: 520 PHGKSKGYAFIEF---ASFEDAKEALNSCNKMEIEGRTIRLELQGPRGSPNARSQPSKTL 576
Query: 203 YVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTE 262
+VK L E+ T+++LK+ FE G + ++ ++G K FGFV F+ A A + E
Sbjct: 577 FVKGLSEDTTEETLKESFE--GSVRARIVTDRETGSSKG-FGFVDFNSEEDAKAAKEAME 633
Query: 263 KYEIDGKNLECSLAKPEADQRSSGTSNSQKPVVLPTYPHRLGYGMVGGAYGGIGAGYGAA 322
EIDG + AKP+ + G R G+G GG GG G G+G
Sbjct: 634 DGEIDGNKVTLDWAKPKGEGGFGGRGGG-----------RGGFGGRGGGRGGRG-GFGGR 681
Query: 323 G 323
G
Sbjct: 682 G 682
Score = 63.5 bits (153), Expect = 8e-10
Identities = 53/211 (25%), Positives = 99/211 (46%), Gaps = 18/211 (8%)
Query: 91 EFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRG 150
E K +KI+ S LFIGN+ +V ++K ++++ +L +G NR
Sbjct: 295 EAKKQKIEGSEPTTPFNLFIGNLNPNKSVAELKVAISEL---FAKNDLAAVDVRTGTNRK 351
Query: 151 FAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVSQVKAVYVKNLPEN 210
F ++++ + AE + + + K+ N + +P+ +S V + + KNL N
Sbjct: 352 FGYVDFES---AEDLEKALELTGLKVFGNE--IKLEKPKGRDSKKVRAARTLLAKNLSFN 406
Query: 211 ITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKN 270
IT+D LK++FE +I V ++ G+ K ++ F + A K L+ + EIDG++
Sbjct: 407 ITEDELKEVFEDAVEIRLV----SQDGRSKG-IAYIEFKSEADAEKNLEEKQGAEIDGRS 461
Query: 271 LECSLA-----KPEADQRSSGTSNSQKPVVL 296
+ + E ++S S K +VL
Sbjct: 462 VSLYYTGEKGQRQERTGKNSTWSGESKTLVL 492
Score = 58.9 bits (141), Expect = 2e-08
Identities = 41/175 (23%), Positives = 85/175 (48%), Gaps = 21/175 (12%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S + + ++ + +EE L Q V E + + G+ KGYAF+ F + E A +A+
Sbjct: 487 SKTLVLSNLSYSATEETL----QEVFEKATFIKVPQNPHGKSKGYAFIEFASFEDAKEAL 542
Query: 85 EELNNSEFKGKKIKC----------SSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVI 134
N E +G+ I+ + SQ LF+ + + T E +K+ G +
Sbjct: 543 NSCNKMEIEGRTIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESF----EGSV 598
Query: 135 SIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPR 189
++ D + +G ++GF F+++ + A+ +++ M + +++ N T+ WA+P+
Sbjct: 599 RARIVTD-RETGSSKGFGFVDFNSEEDAKAAKEAMEDG--EIDGNKVTLDWAKPK 650
>PABP_YEAST (P04147) Polyadenylate-binding protein, cytoplasmic and
nuclear (Poly(A)-binding protein) (PABP) (ARS consensus
binding protein ACBP-67) (Polyadenylate tail-binding
protein)
Length = 576
Score = 86.7 bits (213), Expect = 9e-17
Identities = 74/291 (25%), Positives = 134/291 (45%), Gaps = 18/291 (6%)
Query: 4 NHTNDEVEKKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKES 63
N +D+ + +E ++ S+ +Y+G + +VSE L +G VS +R+ + +
Sbjct: 15 NIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAIT 74
Query: 64 GERKGYAFVAFKTKELASQAIEELNNSEFKGKKIKCSSSQ---AKHRLFIGNIPKKWTVE 120
GYA+V F E +AIE+LN + KG+ + SQ + + GNI K
Sbjct: 75 KTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHP 134
Query: 121 DM-KKVVAD---VGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKL 176
D+ K + D V ++S ++ D +G+++GF F+ + A ++ + N L
Sbjct: 135 DIDNKALYDTFSVFGDILSSKIATD--ENGKSKGFGFVHFEEEGAA---KEAIDALNGML 189
Query: 177 ENN-----APTVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVL 231
N AP +S E + + +YVKN+ T + ++LF G I L
Sbjct: 190 LNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASL 249
Query: 232 PPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQ 282
G+ K FGFV++ A+KA++ E++G+ L A+ + ++
Sbjct: 250 EKDADGKLKG-FGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 299
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/288 (26%), Positives = 135/288 (46%), Gaps = 35/288 (12%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S ++I + ++ + L G++ +I E+G+ KG+ FV F+ + A +AI
Sbjct: 124 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIA-TDENGKSKGFGFVHFEEEGAAKEAI 182
Query: 85 EELNNSEFKGKKI--------KCSSSQAKH------RLFIGNIPKKWTVEDMKKVVADVG 130
+ LN G++I K SQ + L++ NI + T E +++ A G
Sbjct: 183 DALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 242
Query: 131 PGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRN 190
P ++S L KD + G+ +GF F+ Y H A + + +++S +L V A+ +N
Sbjct: 243 P-IVSASLEKD--ADGKLKGFGFVNYEKHEDAVKAVEALNDS--ELNGEKLYVGRAQKKN 297
Query: 191 S--------------ESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKS 236
E A Q ++VKNL +++ + L++ F +G IT + ++
Sbjct: 298 ERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN 357
Query: 237 GQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
G+ K FGFV FS A KA+ + + GK L ++A+ + +RS
Sbjct: 358 GKSKG-FGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRS 404
Score = 33.5 bits (75), Expect = 0.88
Identities = 22/123 (17%), Positives = 58/123 (46%), Gaps = 5/123 (4%)
Query: 167 QKMSNSNFKLENNAPTVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKI 226
+++ N N + ++ + +E ++ E+S+ S +YV +L ++++ L +F G +
Sbjct: 9 EQLENLNIQ-DDQKQAATGSESQSVENSSAS----LYVGDLEPSVSEAHLYDIFSPIGSV 63
Query: 227 TKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSG 286
+ + + + + +V+F+D + KA++ I G+ ++ + R G
Sbjct: 64 SSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKG 123
Query: 287 TSN 289
+ N
Sbjct: 124 SGN 126
>PAB4_HUMAN (Q13310) Polyadenylate-binding protein 4
(Poly(A)-binding protein 4) (PABP 4) (Inducible
poly(A)-binding protein) (iPABP) (Activated-platelet
protein-1) (APP-1)
Length = 644
Score = 85.9 bits (211), Expect = 2e-16
Identities = 76/295 (25%), Positives = 139/295 (46%), Gaps = 37/295 (12%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
V+I + ++ + L + G + +++ E+G KGYAFV F+T+E A +AIE++
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVV-CDENGS-KGYAFVHFETQEAADKAIEKM 158
Query: 88 NN----------SEFKGKKIKCSSSQAKHR----LFIGNIPKKWTVEDMKKVVADVGPGV 133
N FK +K + + AK + ++I N ++ E +K++ + G
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGK-T 217
Query: 134 ISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNF------------KLENNAP 181
+S+++++D +G+++GF F+ Y H A + ++M+ K+E A
Sbjct: 218 LSVKVMRD--PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAE 275
Query: 182 TVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKIT--KVVLPPAKSGQE 239
E E + Q +Y+KNL + I + L+K F G IT KV+L +S
Sbjct: 276 LKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRS--- 332
Query: 240 KSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSNSQKPV 294
FGFV FS A KA+ + K L +LA+ + ++++ T+ + V
Sbjct: 333 -KGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRV 386
Score = 83.2 bits (204), Expect = 1e-15
Identities = 71/272 (26%), Positives = 123/272 (45%), Gaps = 21/272 (7%)
Query: 26 SEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIE 85
+ +Y+G + ++V+E L G V +R+ + + GYA+V F+ A +A++
Sbjct: 11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 86 ELNNSEFKGKKIKCSSSQAKHRL--------FIGNIPKKWTVEDMKKVVADVGPGVISIE 137
+N KGK I+ SQ L FI N+ K + + + G ++S +
Sbjct: 71 TMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFG-NILSCK 129
Query: 138 LLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVS 197
++ D S +G+AF+ + A+ + +KM N L N+ E A
Sbjct: 130 VVCDENGS---KGYAFVHFETQEAADKAIEKM---NGMLLNDRKVFVGRFKSRKEREAEL 183
Query: 198 QVKA-----VYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRS 252
KA VY+KN E + +SLK+LF GK V + +G+ K FGFV +
Sbjct: 184 GAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG-FGFVSYEKHE 242
Query: 253 SAMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
A KA++ EI GK + A+ + ++++
Sbjct: 243 DANKAVEEMNGKEISGKIIFVGRAQKKVERQA 274
Score = 62.0 bits (149), Expect = 2e-09
Identities = 51/208 (24%), Positives = 89/208 (42%), Gaps = 32/208 (15%)
Query: 12 KKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAF 71
K++ AEL A + VYI V +E L+ G+ V++M+ +G+ KG+ F
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMR-DPNGKSKGFGF 235
Query: 72 VAFKTKELASQAIEELNNSEFKGKKIKCSSSQAK------------------------HR 107
V+++ E A++A+EE+N E GK I +Q K
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295
Query: 108 LFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQ 167
L+I N+ E ++K + G SI K + GR++GF F+ + + E + +
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFG----SITSAKVMLEDGRSKGFGFVCF---SSPEEATK 348
Query: 168 KMSNSNFKLENNAPTVSWAEPRNSESSA 195
++ N ++ + P R E A
Sbjct: 349 AVTEMNGRIVGSKPLYVALAQRKEERKA 376
>NUCL_MOUSE (P09405) Nucleolin (Protein C23)
Length = 706
Score = 84.0 bits (206), Expect = 6e-16
Identities = 76/299 (25%), Positives = 139/299 (46%), Gaps = 37/299 (12%)
Query: 36 NVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEELNNSEFKGK 95
N++E++L+ + + E+R++ + G+ KG A++ FK++ A + +EE +E G+
Sbjct: 404 NITEDELKEVFE---DAMEIRLVS--QDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGR 458
Query: 96 KIKCSSSQAK-HRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSS--------- 145
+ + K R W+ E V++++ L + + +
Sbjct: 459 SVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFIKVPQNP 518
Query: 146 -GRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVSQVKAVYV 204
G+ +G+AFIE+ A E +++ +++ N K+E T+ ++ S S K ++V
Sbjct: 519 HGKPKGYAFIEF---ASFEDAKEALNSCN-KMEIEGRTIRLELQGSNSRSQPS--KTLFV 572
Query: 205 KNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKY 264
K L E+ T+++LK+ FE G + ++ ++G K FGFV F+ A A + E
Sbjct: 573 KGLSEDTTEETLKESFE--GSVRARIVTDRETGSSKG-FGFVDFNSEEDAKAAKEAMEDG 629
Query: 265 EIDGKNLECSLAKPEADQRSSGTSNSQKPVVLPTYPHRLGYGMVGGAYGGIGAGYGAAG 323
EIDG + AKP+ + G R G+G GG GG G G+G G
Sbjct: 630 EIDGNKVTLDWAKPKGEGGFGGRGGG-----------RGGFGGRGGGRGGRG-GFGGRG 676
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/200 (25%), Positives = 96/200 (48%), Gaps = 15/200 (7%)
Query: 91 EFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRG 150
E K +K++ S LFIGN+ +V ++K ++++ +L +G NR
Sbjct: 293 EAKKQKVEGSEPTTPFNLFIGNLNPNKSVNELKFAISEL---FAKNDLAVVDVRTGTNRK 349
Query: 151 FAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVSQVKAVYVKNLPEN 210
F ++++ + AE + + + K+ N + +P+ +S V + + KNL N
Sbjct: 350 FGYVDFES---AEDLEKALELTGLKVFGNE--IKLEKPKGRDSKKVRAARTLLAKNLSFN 404
Query: 211 ITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKN 270
IT+D LK++FE +I V ++ G+ K ++ F + A K L+ + EIDG++
Sbjct: 405 ITEDELKEVFEDAMEIRLV----SQDGKSKG-IAYIEFKSEADAEKNLEEKQGAEIDGRS 459
Query: 271 LECSLA--KPEADQRSSGTS 288
+ K + +R+ TS
Sbjct: 460 VSLYYTGEKGQRQERTGKTS 479
Score = 60.1 bits (144), Expect = 9e-09
Identities = 39/163 (23%), Positives = 81/163 (48%), Gaps = 13/163 (7%)
Query: 33 IANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEELNNSEF 92
+ +N+S + + V E + + G+ KGYAF+ F + E A +A+ N E
Sbjct: 489 VLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEI 548
Query: 93 KGKKIKC------SSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSG 146
+G+ I+ S SQ LF+ + + T E +K+ G + ++ D + +G
Sbjct: 549 EGRTIRLELQGSNSRSQPSKTLFVKGLSEDTTEETLKESF----EGSVRARIVTD-RETG 603
Query: 147 RNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPR 189
++GF F+++ + A+ +++ M + +++ N T+ WA+P+
Sbjct: 604 SSKGFGFVDFNSEEDAKAAKEAMEDG--EIDGNKVTLDWAKPK 644
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/81 (28%), Positives = 43/81 (52%), Gaps = 3/81 (3%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S +++ G++ + +EE L+ +S RI+ +E+G KG+ FV F ++E A A
Sbjct: 567 SKTLFVKGLSEDTTEETLK---ESFEGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAK 623
Query: 85 EELNNSEFKGKKIKCSSSQAK 105
E + + E G K+ ++ K
Sbjct: 624 EAMEDGEIDGNKVTLDWAKPK 644
>PABP_SCHPO (P31209) Polyadenylate-binding protein (Poly(A)-binding
protein) (PABP)
Length = 653
Score = 82.8 bits (203), Expect = 1e-15
Identities = 73/274 (26%), Positives = 124/274 (44%), Gaps = 22/274 (8%)
Query: 23 PHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQ 82
P S+ +Y+G + +V+E L S+G V+ +R+ + + GYA+V F E +
Sbjct: 77 PTSASLYVGELDPSVTEAMLFELFNSIGPVASIRVCRDAVTRRSLGYAYVNFHNMEDGEK 136
Query: 83 AIEELNNSEFKGKKIKCSSSQAKHRL--------FIGNIPKKWTVEDMKKVVADVGPGVI 134
A++ELN + KG+ + SQ L FI N+ + + + G ++
Sbjct: 137 ALDELNYTLIKGRPCRIMWSQRDPSLRKMGTGNVFIKNLDPAIDNKALHDTFSAFGK-IL 195
Query: 135 SIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPT-VSWAEPRNSES 193
S ++ D G +G+ F+ + + E + + + N L N+ V R
Sbjct: 196 SCKVAVD--ELGNAKGYGFVHFDS---VESANAAIEHVNGMLLNDKKVYVGHHVSRRERQ 250
Query: 194 SAVSQVKA----VYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSR-FGFVHF 248
S V +KA VY+KNL IT+ LF G+IT + L K +K R FGFV++
Sbjct: 251 SKVEALKANFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSL--VKDQNDKPRGFGFVNY 308
Query: 249 SDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQ 282
++ A KA+ E GK L A+ + ++
Sbjct: 309 ANHECAQKAVDELNDKEYKGKKLYVGRAQKKHER 342
Score = 62.8 bits (151), Expect = 1e-09
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 28/169 (16%)
Query: 12 KKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAF 71
+++ +++ AL + + VYI + ++E++ GE++ + ++K ++ + +G+ F
Sbjct: 247 RERQSKVEALKANFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSLVK-DQNDKPRGFGF 305
Query: 72 VAFKTKELASQAIEELNNSEFKGKKIKCSSSQAKH------------------------R 107
V + E A +A++ELN+ E+KGKK+ +Q KH
Sbjct: 306 VNYANHECAQKAVDELNDKEYKGKKLYVGRAQKKHEREEELRKRYEQMKLEKMNKYQGVN 365
Query: 108 LFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRGFAFIEY 156
LFI N+ + E +K + G + S +++ D Q G+++GF F+ Y
Sbjct: 366 LFIKNLQDEVDDERLKAEFSAFGT-ITSAKIMTDEQ--GKSKGFGFVCY 411
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/101 (27%), Positives = 51/101 (49%), Gaps = 5/101 (4%)
Query: 9 EVEKKKHAELLALPPHSS----EVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESG 64
E E +K E + L + ++I + + V +E L+ + G ++ +IM E G
Sbjct: 343 EEELRKRYEQMKLEKMNKYQGVNLFIKNLQDEVDDERLKAEFSAFGTITSAKIM-TDEQG 401
Query: 65 ERKGYAFVAFKTKELASQAIEELNNSEFKGKKIKCSSSQAK 105
+ KG+ FV + T E A++A+ E+N GK + + +Q K
Sbjct: 402 KSKGFGFVCYTTPEEANKAVTEMNQRMLAGKPLYVALAQRK 442
Score = 33.1 bits (74), Expect = 1.2
Identities = 26/114 (22%), Positives = 46/114 (39%), Gaps = 5/114 (4%)
Query: 181 PTVSWAEPRNSESSAVSQVKA-----VYVKNLPENITQDSLKKLFEHHGKITKVVLPPAK 235
P+ S + P N+ S A A +YV L ++T+ L +LF G + + +
Sbjct: 56 PSESTSTPTNASSVATPSGTAPTSASLYVGELDPSVTEAMLFELFNSIGPVASIRVCRDA 115
Query: 236 SGQEKSRFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSN 289
+ + +V+F + KAL I G+ ++ + R GT N
Sbjct: 116 VTRRSLGYAYVNFHNMEDGEKALDELNYTLIKGRPCRIMWSQRDPSLRKMGTGN 169
>PABX_ARATH (Q9ZQA8) Probable polyadenylate-binding protein
At2g36660 (Poly(A)-binding protein At2g36660) (PABP)
Length = 609
Score = 82.0 bits (201), Expect = 2e-15
Identities = 64/278 (23%), Positives = 129/278 (46%), Gaps = 27/278 (9%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
V++ + +V+ L+ + G + ++ E G+ +GY FV F+ ++ A AI+ L
Sbjct: 114 VFVKNLPESVTNAVLQDMFKKFGNIVSCKVATL-EDGKSRGYGFVQFEQEDAAHAAIQTL 172
Query: 88 NNS----------EFKGKKIKCSSSQAKHRLFIGNIPKKWTVEDMKKVVADVGPGVISIE 137
N++ +F K + + L++ N+ + + +++ A+ G ++S+
Sbjct: 173 NSTIVADKEIYVGKFMKKTDRVKPEEKYTNLYMKNLDADVSEDLLREKFAEFGK-IVSLA 231
Query: 138 LLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNF------------KLENNAPTVSW 185
+ KD + RG+AF+ + N A + + ++ + F K E
Sbjct: 232 IAKD--ENRLCRGYAFVNFDNPEDARRAAETVNGTKFGSKCLYVGRAQKKAEREQLLREQ 289
Query: 186 AEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGF 245
+ ++ E +++V +YVKN+ +T++ L+K F G IT L + G+ K FGF
Sbjct: 290 FKEKHEEQKMIAKVSNIYVKNVNVAVTEEELRKHFSQCGTITSTKLMCDEKGKSKG-FGF 348
Query: 246 VHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQR 283
V FS A+ A+K GK L ++A+ + D++
Sbjct: 349 VCFSTPEEAIDAVKTFHGQMFHGKPLYVAIAQKKEDRK 386
Score = 69.7 bits (169), Expect = 1e-11
Identities = 63/272 (23%), Positives = 123/272 (45%), Gaps = 22/272 (8%)
Query: 23 PHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQ 82
P ++ +Y+G + +V+E L ++ VR+ K SG Y + F +++ A+
Sbjct: 21 PVTASLYVGDLHPSVTEGILYDAFAEFKSLTSVRLCKDASSGRSLCYGYANFLSRQDANL 80
Query: 83 AIEELNNSEFKGKKIKCSSS--------QAKHRLFIGNIPKKWT---VEDMKKVVADVGP 131
AIE+ NNS GK I+ S +F+ N+P+ T ++DM K ++
Sbjct: 81 AIEKKNNSLLNGKMIRVMWSVRAPDARRNGVGNVFVKNLPESVTNAVLQDMFKKFGNIVS 140
Query: 132 GVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNS 191
+ L+D G++RG+ F+++ A + Q + NS + + + +
Sbjct: 141 --CKVATLED----GKSRGYGFVQFEQEDAAHAAIQTL-NSTIVADKEIYVGKFMK-KTD 192
Query: 192 ESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSR-FGFVHFSD 250
+ +Y+KNL ++++D L++ F GKI + + AK R + FV+F +
Sbjct: 193 RVKPEEKYTNLYMKNLDADVSEDLLREKFAEFGKIVSLAI--AKDENRLCRGYAFVNFDN 250
Query: 251 RSSAMKALKNTEKYEIDGKNLECSLAKPEADQ 282
A +A + + K L A+ +A++
Sbjct: 251 PEDARRAAETVNGTKFGSKCLYVGRAQKKAER 282
Score = 50.1 bits (118), Expect = 9e-06
Identities = 29/94 (30%), Positives = 49/94 (51%), Gaps = 2/94 (2%)
Query: 12 KKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAF 71
K+KH E + S+ +Y+ + V+EE+LR G ++ ++M E G+ KG+ F
Sbjct: 291 KEKHEEQKMIAKVSN-IYVKNVNVAVTEEELRKHFSQCGTITSTKLM-CDEKGKSKGFGF 348
Query: 72 VAFKTKELASQAIEELNNSEFKGKKIKCSSSQAK 105
V F T E A A++ + F GK + + +Q K
Sbjct: 349 VCFSTPEEAIDAVKTFHGQMFHGKPLYVAIAQKK 382
Score = 35.4 bits (80), Expect = 0.23
Identities = 24/104 (23%), Positives = 43/104 (41%)
Query: 186 AEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGF 245
A +S S+ ++YV +L ++T+ L F +T V L S +G+
Sbjct: 10 AADASSSGSSSPVTASLYVGDLHPSVTEGILYDAFAEFKSLTSVRLCKDASSGRSLCYGY 69
Query: 246 VHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSN 289
+F R A A++ ++GK + + D R +G N
Sbjct: 70 ANFLSRQDANLAIEKKNNSLLNGKMIRVMWSVRAPDARRNGVGN 113
>NSR1_YEAST (P27476) Nuclear localization sequence binding protein
(P67)
Length = 414
Score = 80.5 bits (197), Expect = 6e-15
Identities = 62/259 (23%), Positives = 117/259 (44%), Gaps = 27/259 (10%)
Query: 77 KELASQAIEELNNSEFKGKKIKCSSSQAKHRLFIGNIPKKWTVED--MKKVVADVGPGVI 134
K+ S+ EE + E KK K ++ +F+G + W+++D +KK +G GVI
Sbjct: 139 KKRKSEDAEEEEDEESSNKKQKNEETEEPATIFVGRL--SWSIDDEWLKKEFEHIG-GVI 195
Query: 135 SIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNS-------NFKLENNAPTVSWAE 187
++ + + + R+RG+ ++++ N + AE + Q+M N + + P +
Sbjct: 196 GARVIYE-RGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDR 254
Query: 188 PRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVH 247
+ + +++ NL N +D++ +LF HG++ V +P ++ FG+V
Sbjct: 255 AKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQ 314
Query: 248 FSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRSSGTSNSQKPVVLPTYPHRLGYGM 307
FS+ A KAL + ID + + + P + G S+ G+G
Sbjct: 315 FSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPN-NDGGRGGSR------------GFGG 361
Query: 308 VGGAYGGIGAGYGAAGFAQ 326
GG GG G+G G A+
Sbjct: 362 RGGGRGG-NRGFGGRGGAR 379
Score = 51.2 bits (121), Expect = 4e-06
Identities = 36/181 (19%), Positives = 84/181 (45%), Gaps = 23/181 (12%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
+++G ++ ++ +E L+ + +G V R++ + + +GY +V F+ K A +AI+E+
Sbjct: 170 IFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEM 229
Query: 88 NNSEFKGKKIKCSSSQAK-------------------HRLFIGNIPKKWTVEDMKKVVAD 128
E G+ I C S +K LF+GN+ + + ++ A
Sbjct: 230 QGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAK 289
Query: 129 VGPGVISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEP 188
G V+S+ + ++ + +GF ++++ N A+ + + ++N + ++ P
Sbjct: 290 HGE-VVSVRIPTHPETE-QPKGFGYVQFSNMEDAKKALDALQGE--YIDNRPVRLDFSSP 345
Query: 189 R 189
R
Sbjct: 346 R 346
Score = 36.6 bits (83), Expect = 0.10
Identities = 19/81 (23%), Positives = 37/81 (45%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
S +++G ++ N + + GEV VRI E+ + KG+ +V F E A +A+
Sbjct: 266 SDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKAL 325
Query: 85 EELNNSEFKGKKIKCSSSQAK 105
+ L + ++ S +
Sbjct: 326 DALQGEYIDNRPVRLDFSSPR 346
>PAB3_HUMAN (Q9H361) Polyadenylate-binding protein 3
(Poly(A)-binding protein 3) (PABP 3) (Testis-specific
poly(A)-binding protein)
Length = 631
Score = 80.1 bits (196), Expect = 8e-15
Identities = 65/272 (23%), Positives = 121/272 (43%), Gaps = 19/272 (6%)
Query: 25 SSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAI 84
++ +Y+G + +V+E L G + +RI + + YA+V F+ + A A+
Sbjct: 10 TASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHAL 69
Query: 85 EELNNSEFKGKKIKCSSSQAKHRL--------FIGNIPKKWTVEDMKKVVADVGPGVISI 136
+ +N KGK ++ SQ L F+ N+ K + + V+ G ++S
Sbjct: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFG-NILSC 128
Query: 137 ELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAV 196
++ D S +G+ F+ + H AE + +KM + L V + R + +
Sbjct: 129 NVVCDENGS---KGYGFVHFETHEAAERAIKKM--NGMLLNGRKVFVGQFKSRKEREAEL 183
Query: 197 ----SQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRS 252
+ VY+KN E++ + LK LF G V + +SG+ K FGFV F
Sbjct: 184 GARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG-FGFVSFERHE 242
Query: 253 SAMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
A KA+ E++GK + A+ + ++++
Sbjct: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQT 274
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/283 (22%), Positives = 123/283 (42%), Gaps = 33/283 (11%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
+++ + +++ + L + G + ++ E+G KGY FV F+T E A +AI+++
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVV-CDENGS-KGYGFVHFETHEAAERAIKKM 158
Query: 88 NNSEFKGKKIKCSSSQAKHR--------------LFIGNIPKKWTVEDMKKVVADVGPGV 133
N G+K+ +++ ++I N + E +K + GP
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPA- 217
Query: 134 ISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNF------------KLENNAP 181
+S++++ D SG+++GF F+ + H A+ + +M+ K+E
Sbjct: 218 LSVKVMTD--ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTE 275
Query: 182 TVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKS 241
E + QV +YVKNL + I + L+K F G IT + G
Sbjct: 276 LKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKV--MMEGGRSK 333
Query: 242 RFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
FGFV FS A KA+ + K L +LA+ + ++++
Sbjct: 334 GFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQA 376
Score = 60.1 bits (144), Expect = 9e-09
Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 12 KKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAF 71
K++ AEL A VYI ++ +E L+ G V++M ESG+ KG+ F
Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVM-TDESGKSKGFGF 235
Query: 72 VAFKTKELASQAIEELNNSEFKGKKIKCSSSQAK------------------------HR 107
V+F+ E A +A++E+N E GK+I +Q K
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 295
Query: 108 LFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRGFAFI 154
L++ N+ E ++K + G +I K + GR++GF F+
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFG----TITSAKVMMEGGRSKGFGFV 338
>TIAR_HUMAN (Q01085) Nucleolysin TIAR (TIA-1 related protein)
Length = 375
Score = 78.2 bits (191), Expect = 3e-14
Identities = 74/331 (22%), Positives = 140/331 (41%), Gaps = 44/331 (13%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
+Y+G ++ +V+E + +G +++ S + Y FV F A+ A+ +
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
Query: 88 NNSEFKGKKIKCS-----SSQAKH-----RLFIGNIPKKWTVEDMKKVVADVGPGVISIE 137
N + GK++K + SSQ K +F+G++ + T ED+K A G +
Sbjct: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK-ISDAR 127
Query: 138 LLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNS---NFKLENNAPTVSWAEPRNSESS 194
++KD+ ++G+++G+ F+ +YN AE + M ++ N T P++++ +
Sbjct: 128 VVKDM-ATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
Query: 195 AVSQVK-------------AVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKS 241
Q++ VY + +T +++ F G+I ++ + P K
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKG----- 241
Query: 242 RFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAK--PEADQRSSGTSNSQKPVVLPTY 299
+ FV FS SA A+ + I+G ++C K P+ + SQ Y
Sbjct: 242 -YSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY 300
Query: 300 --PHRLGYGMVGG----AYGGIGAGYGAAGF 324
P + G M G YG G + GF
Sbjct: 301 GNPQQYGQYMANGWQVPPYGVYGQPWNQQGF 331
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 23 PHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQ 82
P + VY GGIA+ ++++ +R G++ E+R+ KGY+FV F T E A+
Sbjct: 202 PKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFP------EKGYSFVRFSTHESAAH 255
Query: 83 AIEELNNSEFKGKKIKC 99
AI +N + +G +KC
Sbjct: 256 AIVSVNGTTIEGHVVKC 272
>PAB1_RAT (Q9EPH8) Polyadenylate-binding protein 1 (Poly(A)-binding
protein 1) (PABP 1)
Length = 636
Score = 78.2 bits (191), Expect = 3e-14
Identities = 67/272 (24%), Positives = 121/272 (43%), Gaps = 21/272 (7%)
Query: 26 SEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIE 85
+ +Y+G + +V+E L G + +R+ + + GYA+V F+ A +A++
Sbjct: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
Query: 86 ELNNSEFKGKKIKCSSSQAKHRL--------FIGNIPKKWTVEDMKKVVADVGPGVISIE 137
+N KGK ++ SQ L FI N+ K + + + G ++S +
Sbjct: 71 TMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFG-NILSCK 129
Query: 138 LLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNFKLENNAPTVSWAEPRNSESSAVS 197
++ D S +G+ F+ + AE + +KM N L N+ E A
Sbjct: 130 VVCDENGS---KGYGFVHFETQEAAERAIEKM---NGMLLNDRKVFVGRFKSRKEREAEL 183
Query: 198 QVKA-----VYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKSRFGFVHFSDRS 252
+A VY+KN E++ + LK+LF G V + +SG+ K FGFV F
Sbjct: 184 GARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKG-FGFVSFERHE 242
Query: 253 SAMKALKNTEKYEIDGKNLECSLAKPEADQRS 284
A KA+ E++GK + A+ + ++++
Sbjct: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQT 274
Score = 77.8 bits (190), Expect = 4e-14
Identities = 74/309 (23%), Positives = 131/309 (41%), Gaps = 43/309 (13%)
Query: 28 VYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAFVAFKTKELASQAIEEL 87
++I + ++ + L + G + +++ E+G KGY FV F+T+E A +AIE++
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVV-CDENGS-KGYGFVHFETQEAAERAIEKM 158
Query: 88 NN----------SEFKGKKIKCSSSQAKHR----LFIGNIPKKWTVEDMKKVVADVGPGV 133
N FK +K + + A+ + ++I N + E +K++ GP
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPA- 217
Query: 134 ISIELLKDLQSSGRNRGFAFIEYYNHACAEYSRQKMSNSNF------------KLENNAP 181
+S++++ D SG+++GF F+ + H A+ + +M+ K+E
Sbjct: 218 LSVKVMTD--ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTE 275
Query: 182 TVSWAEPRNSESSAVSQVKAVYVKNLPENITQDSLKKLFEHHGKITKVVLPPAKSGQEKS 241
E + Q +YVKNL + I + L+K F G IT + G
Sbjct: 276 LKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKV--MMEGGRSK 333
Query: 242 RFGFVHFSDRSSAMKALKNTEKYEIDGKNLECSLAKPEAD----------QRSSGTSNSQ 291
FGFV FS A KA+ + K L +LA+ + + QR +
Sbjct: 334 GFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVP 393
Query: 292 KPVVLPTYP 300
PV+ P P
Sbjct: 394 NPVINPYQP 402
Score = 60.5 bits (145), Expect = 7e-09
Identities = 44/167 (26%), Positives = 74/167 (43%), Gaps = 29/167 (17%)
Query: 12 KKKHAELLALPPHSSEVYIGGIANNVSEEDLRVFCQSVGEVSEVRIMKAKESGERKGYAF 71
K++ AEL A + VYI ++ +E L+ G V++M ESG+ KG+ F
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVM-TDESGKSKGFGF 235
Query: 72 VAFKTKELASQAIEELNNSEFKGKKIKCSSSQAK------------------------HR 107
V+F+ E A +A++E+N E GK+I +Q K
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN 295
Query: 108 LFIGNIPKKWTVEDMKKVVADVGPGVISIELLKDLQSSGRNRGFAFI 154
L++ N+ E ++K + G +I K + GR++GF F+
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFG----TITSAKVMMEGGRSKGFGFV 338
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.316 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,430,465
Number of Sequences: 164201
Number of extensions: 1798701
Number of successful extensions: 9315
Number of sequences better than 10.0: 383
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 7835
Number of HSP's gapped (non-prelim): 1135
length of query: 370
length of database: 59,974,054
effective HSP length: 112
effective length of query: 258
effective length of database: 41,583,542
effective search space: 10728553836
effective search space used: 10728553836
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Lotus: description of TM0010.2